Updated: 06/14/2016 - Website operated by Leptigen

Alphamine Review - Does This Thermogenic Powder Really Work? Are dangerous ingredients and side effects deal breakers?

Editor's Review: 3.5 / 5.0
Alphamine Review

Bottom Line: You want to lose weight with a product that works, not just says it will work. In my never-ending search to discover the best diet product, this week I reviewed Alphamine. We did some serious research and took an in-depth look, examining the side effects, ingredients, scientific studies and level of customer care. We also took a look at plenty of user comments from around the web. Finally, we summed up all the facts and dieter responses to give you the info you need.

EDITOR'S TIP: Substitute Alphamine with a proven fat burner such as Leptigen for better results.

What is Alphamine?

To start, Alphamine is a “powerful thermogenic powder” that is made by Physique Enhancing Science. The ingredients are choline bitartrate, alpha-hydroxyisocaproic acid, eucommia ulmoides extract, olive leaf, caffeine anhydrous, nelumbo nucifera seed, yohimbe bark and higenamine. It is available in flavors such as cherry lemonade, fruit punch and raspberry lemonade. Put simply, it is intended to increase fat loss and function as a powerful stimulant. You add one scoop to 4-5 ounces of water and consume 15-30 minutes prior to breakfast. A second dose can be taken five hours later if needed.

From what we gathered, Alphamine has been available since 2012. This supplement is for sale through several online stores and plenty of customer reviews are posted on the web. Furthermore, this product contains some natural plant extracts, but read on…

Questionable Ingredients – “Proceed With Caution?”

The first thing we considered with Alphamine ingredients was the potential for health issues. “After taking a close look at the label for the powder, we noticed that this supplement contains some questionable elements such as higenamine, which can lead to heart problems, in some cases,” says our Research Editor.

  • One customer revealed, “This stuff makes me feel like what I imagine smoking a whole bunch of crack would make you feel like.”
  • “The side effects, specifically nausea, are simply too severe for me,” said another user.

Reported Side Effects – “Something to Notice”

According to the customer feedback we found on distributor websites like Amazon, there are certainly cause some Alphamine side effects.

  • One user stated, “This stuff gave me a voracious appetite. The first week I used it – I gained 4 pounds.”
  • Another dieter commented, “Made me having a nervous cracked out type of feeling even at lowest recommended dosage. Would not recommend this product.”

Our research has shown that if one aspect of a fat-loss supplement or weight-loss program is significantly concerning (questionable ingredients, serious side effects, unpleasant taste) the odds of long-term success are slim. This means if Alphamine does lead to adverse reactions in a lot of people, this could be a serious dilemma.

The Science – “Clinical Proof?”

We at DietSpotlight prefer to see published clinical science that back a diet product and its ingredients. However, we were unable to find any studies that support Alphamine for fat loss and weight reduction. What we did find is an extensive warning label on the bottle, which is a concern.

The Bottom Line – Does Alphamine Work?

So, is it time to run out and but this supplement? Even though Alphamine is available in a few different flavors and is easy to purchase online, we have doubts recommending this one for safe and effective weight-loss. Not only does it contain potentially dangerous ingredients, but there are also numerous negative user reviews posted on the web. These factors should not be overlooked.

If you would like to drop some serious fat and rock your best body, we recommend you choose a diet formula that contains safe ingredients, does not lead to side effects and is clinically proven.

Among the best products we’ve seen in 2016 is one called Leptigen. This weight-loss pill contains a proprietary blend of four unique ingredients that have been proven in documented scientific research to encourage fat loss and kick-start metabolism. We did not pinpoint any customer complaints concerning harmful adverse effects and dieter feedback posted on the web reveals people are seeing solid results.

Also, the makers of Leptigen are so confident in their product they’re offering a Special Trial Offer, which is a good sign.

Leptigen is available around the world with reliable, fast worldwide shipping. For customers in Australia, the UK, and others, simply choose your country from the drop down menu on the order page. That’s it – simple!

Learn More About Leptigen »
GD Star Rating

How Does Alphamine Compare?

Previous Alphamine Review (Updated June 16, 2014):

What You Should Know

Click Here To See Our Highest Rated Review

Stores like GNC offer all kinds of health supplements, multivitamins, energy bars, muscle building powders, and diet pills. Nowadays you can even access GNC online. One product you will find on this website is Alphamine powder. It goes for a retail price of $59.99, but may be on sale. It is one of various weight loss supplements available at this point. It comes in fruit punch flavor, and is simply mixed with a glass of water, and then consumed. A single container is a one-month supply.


  • Alphamine FIT Matrix 1567.00 mg
  • Citric Acid
  • Natural and Artificial Flavors
  • Silicon Dioxide
  • Sucralose
  • Acesulfame-K
  • Beet Juice Concentrate Powder

Product Features

Alphamine is touted as a fat igniting technology. This powder formula can be used daily to assist with weight loss, appetite suppression, and improving mood. It is described as an innovative stimulant system with a LBM preservation system. It contains “revolutionary” hardening agents, and works as a selective beta-agonist. With regular use, this formula is supposed to improve thermo genesis, so your body will burn off calories and fat more rapidly. There is no mention of a refund guarantee with Alphamine powder.

The ingredients for Alphamine powder are not really elaborated on. However, it is revealed that this supplement contains an Alphamine FIT Matrix of 1567.00 milligrams. This matrix assists by increasing thermo genesis, enhancing mood, and suppressing hunger. As far as other key ingredients are concerned, there are none. Just so you are aware, Alphamine could lead to some side effects. For instance, some people have experienced rapid heartbeat and jitteriness. Therefore you might want to speak with a professional before trying this type of supplement.

See Our Featured


  • Some user testimonials are posted on the GNC website.
  • Minimal ingredients appear to be used in Alphamine powder.
  • This product comes in fruit punch flavor, which some people will appreciate.


  • Very minimal information is provided on Alphamine.
  • This product does not suppress appetite.
  • The cost of this powder formula is $59.99.
  • Unfortunately this product may cause unwanted side effects.
  • There are more convenient pill formulas available to assist with weight loss.


After reviewing a few different websites that offer Alphamine powder, it is clear that some people have found this supplement useful for weight loss or toning up. It is nice to see that there are some customer testimonials out there supporting this product. Then again, this does not mean Alphamine is safe and effective for everyone. As you may have noticed, this powder contains an Alphamine FIT Matrix, which is a little vague. After all, this matrix could contain all kinds of stimulants and other substances. This is why it is wise to proceed with caution.

Alphamine Questions & Answers:

We sorted through hundreds of user reviews about Alphamine to craft this useful FAQ.

What are the side effects of Alphamine?

Alphamine side effects may include increased appetite, anxiety and nervousness, and insomnia.

What are the ingredients in Alphamine?

Alphamine ingredients include choline bitartrate, alpha-hydroxyisocaproic acid, eucommia ulmoides extract, olive leaf, caffeine anhydrous, nelumbo nucifera seed, yohimbe bark and higenamine.

Does Alphamine work?

There aren’t any clinical studies to support the idea that Alphamine works for weight-loss.

If you’re looking for a supplement with clinically tested ingredients, you may want to take a gander at Leptigen.

How much does Alphamine cost?

You’ll spend $59.99 on a container with 84 servings.

What is Alphamine’s BBB rating?

This company is not accredited by the BBB.

How should I take Alphamine?

Add a single scoop to four to five ounces of water. Drink 15 to 30 minutes before breakfast. If needed, repeat five hours later.

Can I take Alphamine if I have a health condition?

If you have a health condition, talk with your doctor to make sure you are healthy enough to use this supplement.

What do users like about Alphamine?

Users like that you can find it in multiple flavors.

What do users NOT like about Alphamine?

Some users complained about Alphamine’s taste, even though there were multiple flavors to choose from. Others worried about side effects.

How do I contact the Alphamine customer service department?

You can get in touch with the Alphamine customer service department by phone at 1-888-885-0195. They are available between the hours of 9 am to noon EST and 1pm to 4pm EST. You can also fill out the contact form.

Is Alphamine available in multiple flavors?

Yes. You can find it in cherry lemonade, raspberry lemonade, and fruit punch flavors.

Is a blender required?

No, you don’t need to use a blender.p>

Does Alphamine come with a guarantee?

Yes. If you are not happy with the product, there is a 100% money-back guarantee.

Do you know of any special deals or discounts on Alphamine?

We couldn’t find any deals or discounts on Alphamine, but for anyone who is interested, there is a Special Trial Offer of Leptigen. It a weight-loss supplement made with clinically tested ingredients. Click here to give it a try.

Alphamine Ingredients:

We dug deep into the Alphamine ingredients to give you the details you need.

Caffeine Anhydrous

Caffeine anhydrous is a dehydrated form of caffeine.

What is it Supposed to Do?

It is a stronger version of the stimulant caffeine.

Clinical Research

According to a study published in Journal of Thermal Analysis, “Caffeine has been found to display a low-temperatureβ- and a high-temperatureα-modification.”

Clinical research is an important part of the equation when it comes to choosing a diet supplement. You may want to take a look at a product like Leptigen, which is formulated with clinically tested ingredients.

Yohimbe Bark

The bark of a tree native to Western Africa, it is commonly used in medicine and supplements.

What is it Supposed to Do?

It is supposed to help support sexual function, and serve as a treatment for erectile dysfunction., while also helping to improve athletic performance.

Clinical Research

According to a study published in Phytopharmacy: An Evidence-Based Guide to Herbal Medical Products, “Clinical evidence, pre-clinical evidence, mechanisms of action, interactions, contraindications, information about adverse effects and dosage of Yohimbe (Pausinystalia johimbe). Yohimbe is recommended for erectile dysfunction (ED) in males and loss of libido in females; it has also been advocated as an aid to weight loss and to enhance exercise tolerance and muscle development in bodybuilders.”

Olive Leaf

This is the leaf of the olive tree.

What is it Supposed to Do?

It is supposed to help address blood sugar levels and enhance insulin activity.

Clinical Research

According to a study published in Planta Medica, “The hypoglycemic activity of this compound may result from two mechanisms: (a) potentiation of glucose-induced insulin release, and (b) increased peripheral uptake of glucose.”

Choline Bitartrate

Choline is similar to the B vitamins, and can be made in the liver. IT can also be found in foods, including muscle meats, liver, wheat germ, eggs, peas, nuts, and beans.

What is it Supposed to Do?

It is used to treat a number of conditions, but athletes use it to delay fatigue in endurance sports.


This is a chemical found in a number of plant species.

What is it Supposed to Do?

It is a stimulant that’s thought to be the next ephedra, and as such it’s thought to boost the metabolism so it is easier to lose weight.

Nelumbo Nucifera Seed

These are lotus flower seeds.

What is it Supposed to Do?

It has anti-obesogenic properties, and anti-diabetic properties, but does not necessarily help the body burn more fat.

Alpha-Hydroxyisocaproic Acid

This is the end product of leucine metabolism in muscle and connective issue.

What is it Supposed to Do?

It is supposed to help delay the onset of muscle soreness after physical activity.

Eucommia Ulmoides Extract

This comes from a plant traditionally used in Traditional Chinese Medicine.

What is it Supposed to Do?

Though there are no human trials, there animal evidence suggests this supplement may help lower the blood pressure.

Is There Anything Out There That TRULY Works?

We have our eye on a supplement that fits the bill. Leptigen, which is formulated with ingredients that HAVE been clinically tested, may be a good option. All customers can take advantage of a Special Trial Offer, currently available. Click here to give it a try.

Have a comment or question about Alphamine?