Updated: 11/17/2015 - Sponsored by Leptigen

Appethyl Review - Does This Dietary Supplement Work? Are cost and efficacy deal breakers?

Editor's Review: 3.5 / 5.0

Appethyl is a brand new dietary supplement that has really started making a name for itself, so we did one of our in-depth reviews to examine how it might fit into your budget and health; we included customer service, side effects, ingredients, and clinical research in our study. Our last step involved gathering customer reviews from around the web, and then we condensed all that information right here.

EDITOR'S TIP: Substitute Appethyl with a proven fat burner such as Leptigen for better results.

What You Need to Know

Appethyl isn’t a meal replacement plan, but it is designed specifically to suppress the appetite. The product supports weight loss by utilizing thylakoids, small organelles found inside green plant cells that can slow down the digestion process. Appethyl is easy to take; all you need to do is mix one scoop of the powder with water and take it before a meal high in fat. Only one serving is necessary per day. There is also a capsule option, which works as a nice alternative to the grainy powder. For the faint of heart, there is a berry-flavored option to help get the product down.

Appethyl, which was introduced in 2013, won the award for “Best New Functional Ingredient” at the 2013 NutraCon conference, and it is now available in health stores, on its official website, and online on Amazon and similar retailers. We like the natural ingredient (thylakoids) used in Appethyl, and it seems like a fairly easy product to take, but read on…

Price–“Awfully high for one active ingredient!”

As can be expected from any dynamic new product, the cost is rather high. “You will likely see some appetite reduction if you take Appethyl as directed,” said our research editor, “but it costs almost $60.00 for a month’s supply. That’s a lot for a product with only one active ingredient.” Is there any reason to believe that Appethyl is that much better than a number of other appetite suppressants?

“Very expensive product for the results I got,” one user said.

Further review of other appetite suppressants yielded the fact that there are many popular suppressants available for around $20.00. If there is a specific reason that Appethyl costs significantly more than many other suppressants, we weren’t able to find it on the website. Users also need to be careful not to sign up for the autoship feature unless they want to be billed every month.

Scroll below for one of the best products we’ve seen in 2015.

Efficacy– Another Concern

As with most dietary supplements, the promised results don’t always come true for everybody. Upon sampling user reviews, we started noticing a theme. “I’ve been taking Appethyl faithfully as directed. My appetite has not changed, nor has the fat started shrinking as it promises.”

“I know everyone is different, but I didn’t have that much luck,” said another. After further reading, it seems these negative reactions don’t stand alone..

Although Appethyl shows a lot of promise, even one drawback to the product can hurt its long-term success. In this case, the pricing demands a significant commitment on the part of the user to continue using Appethyl for a long period of time. If the cost sits too high for most people to commit to for very long, the chances of it helping them keep weight off aren’t great.

The Science–Is It Solid?

The whole concept of thylakoids is rooted in science, and it appears that the effect of thylakoids on human appetites is rooted in science as well. Several studies, including clinical endeavors at Lund University in Sweden and the Pennington Biomedical Research Center at LSU, point to the fact that thylakoids, when extracted from spinach, slow down the digestive process and lead to a longer feeling of fullness.

Humans are not naturally able to extract thylakoids from green plants during digestion, which is why Appethyl is based on pre-extracted thylakoids from spinach.

Scientific research is not an issue here, but the relationship of Appethyl to weight loss might be. Appetite suppression is only one small part of weight loss, and someone spending money on Appethyl may also need to find a fat burning supplement to stack with it.

The Bottom Line: Does Appethyl Work?

Appethyl is certainly an exciting new product, and we are looking forward to seeing how it’s used in the future. For now, though, the product only focuses on appetite suppression, which is a relatively small slice of the pie. Furthermore, Appethyl is quite expensive and doesn’t work for everyone.

We recommend two things in a supplement if you still need to shed some pounds: first, a good value for your money. Second, a good collection of clinical data to back the product up.

Leptigen is a great new product that we have come across this year. Its proprietary blend of four ingredients boosts metabolism and helps you burn fat, and the ingredients have been clinically verified to do so. It doesn’t have harmful side effects, and user reviews look great so far.

Check out the special trial offer; it’s always reassuring when a company stands behind their product.

Learn More About Leptigen »
GD Star Rating

How Does Appethyl Compare?

Previous Appethyl Review (Updated June 25, 2012):

What You Should Know

Click Here To See Our Highest Rated Review

Appethyl is an ingredient most dieters will not be familiar with because it has not yet hit the market. Green Medical AB is the company behind the ground-breaking spinach extract. The extract was honored to be named one of the finalists for the NutraCon NutrAward as of February 2013. Green Medical Abs official website explains the extract as a derivative of spinach that decreases appetite, reduce waist size and improve glucose and cholesterol levels. There is mention of clinical studies, but no links to such studies. We were able to find some studies on the active portion of Appethyl and appetite.

List of Ingredients

  • Thylakoids

Product Features

Thylakoids are nothing new. When we researched the spinach derivative we found studies from the 1970s, but current studies are also available. According to one study completed in 2009, thylakoids added to one high-fat meal sparked changes in the body that helped ease hunger after the meal. The changes took effect between two and six hours after the meal was consumed. Insulin levels were also affected in a positive manner – reducing insulin reaction to the meal. We found additional, similar studies from 2007. For a relatively unknown weight loss ingredient, thylakoids have a strong clinical history. We are unsure why this ingredient has not been promoted as an appetite suppressant to date, but Appethyl is poised to break the market and make lots of money as the primary source of this (soon-to-be) patented ingredient.

See Our Featured


  • Clinically proven to suppress appetite.
  • Works hours after consumption.
  • Derived from all-natural spinach.
  • Patents pending.
  • Fills a gap in the weight loss market.


  • Not currently used in any weight loss supplements as of February 2013.
  • Does not address increasing metabolism.
  • No large-scale clinical studies have been completed.


Appethyl is an amazing ingredient that could be the answer to weight loss issues for millions of people. Hormonal changes in the brain sparked by Appethyl suppress appetite. The ingredient works as a prebiotic and helps maintain healthy insulin levels. When this ingredient hits the weight loss market, we can expect a long list of new supplements touting the weight loss benefits of Appethyl, but controlling hunger is just one aspect of supplemental weight loss. The best formulas will contain other clinically proven ingredients like caffeine and green tea. We’ll have to wait and see just how the Appethyl story ends or, in this case, begins.

13 User Reviews About Appethyl

Leave comments below
  • 1

    It seems to work for hunger and sweets BUT I seem to have a ache in my side
    for a long time since taking the Appethyl upon test they say I have a fatty liver and every time I drink the Appethyl I notice the ache in my side .
    has anyone else experienced any side affects?


  • 2

    I heard appethyl tablets reviewed on the radio yesterday by a Dr. so I started searching online I can’t seem to find the tablets anywhere. Can you tell me where I can purchase


  • 3

    Where can I buy appethyl tablets


    Your Name

    ProSpinach.com has capsules


  • 4

    i live in a very remote place so i need to know where they sell appethyl


  • 5

    GNC has appidex. They claim that it has appethyl in it. I read the first mag article. I’m going to make the spinach smoothie and add the appidex and yogurt. I just found the hydroxycut appetite control at Walgreens. It is a powder. I am on my way to pick it up. My birthday is in March and I want to have dropped 2 dress sizes. Of course I’ll work out, eat right and yada-yada-yada but for right now this is my motivation!


  • 6
    Debi Bainter

    You need to update as new report out and it came back as being like a gastric bypass without surgery from “FIRST” 1/19/15. Great report out of Sweden. Hydroxycut Appetite Control. Can’t wait to try!!!!!!



    Do you appeythl is like the gastric bypass ?


  • 7

    Is there a trial offer available and if not how/where can I order it?


  • 8
    Kris omakkey

    Will it be in US soon?


  • 9

    When will app ethyl become available here? I read an article that it is available in Scandinavia now. Is there some way to purchase it from a company there?



    Now available in walgreens



    Is Appethyl available in Canada yet?


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