Updated: 05/17/2016 - Website operated by Leptigen

Biphedadrene Review - Does This Fat Burner Work? Are ineffectiveness and side effects deal breakers?

Editor's Review: 3.5 / 5.0
Biphedadrene Review

Biphedadrene isn’t your grandmother’s diet product. We delved into the ingredients, side effects, scientific research and customer service. Furthermore, we scrutinized hundreds of consumer comments and reviews. We then refined and condensed to give you the info you need.

EDITOR'S TIP: Combine Biphedadrene with a proven fat burner such as Leptigen for better results.

What You Need to Know

First off, Biphedadrene is a fat burner containing yerba mate extract, caffeine, arbutin extract, phenylethylamine, damiana leaf extract, methylantine, cayenne powder, cutch tree extract, 5HTP, l dopa and theobromine. The recommend dose is one capsule per day, which supposedly aids in weight-loss. One of the benefits of the supplement is that it’s easy to use.

There is no available information as to when Generix Laboratories introduced Biphedadrene. We noticed that the supplement is available on the official website, a good choice. You can also buy the product on trusted retail websites. We do like that there are some positive customer comments and the company has a favorable BBB rating, but read on…

Ineffectiveness – “No Weight-Loss?”

The first negative pertains to Biphedadrene ingredients being ineffective. “When a company promises rapid weight-loss the dieter expects to see results,” says our Research Editor. “In the case of this supplement, the effects are just not what the buyer wants them to be.”

“I used this along with my diet and exercise program. I saw no difference the 1 month I took BiphedAdrene. I lost more weight without this product,” said a customer.

“I took this pill as directed and I gained weight. I found myself to be hungrier than ever! I cut out carbs and left food on my plate even though I was still hungry and I still gained. I was working out and tried so hard thinking that it will work. Never did,” commented a dieter.

Though some people did not see the loss they were looking for, others saw a few changes. As one put it, “Can I still eat? Sure. But I don’t have the urge to overdo it.”

One dieter said, “It did suppress my hunger and I have lots of energy. ”

Side Effects – “Watch Out!”

According to numerous comments, Biphedadrene side effects are quite troublesome. “I have been using this product for 4 days now, and I have been experiencing bad headaches, jittery, nausea and sleeplessness,” reported a customer.

“I feel bad. My heart starts racing,” said a consumer.

During our research we also came across some people who didn’t have any issues. One customer claimed, “It does not make me jittery or nervous.”

One more user offered, “I stress no side effect so far.”

Based upon our research, if a supplement causes a single problem, like side effects, this could impede long-term success. If Biphedadrene causes reactions, there are concerns.

The Science – “Is it Legit?”

According to the official website, Biphedadrene will boost energy, improve mood and control appetite, but there’s no published clinical research linking the formula to weight-loss. At DietSpotlight, we deal in science to prove claims. If there are no studies, we walk away.

The Bottom Line – Does Biphedadrene Work?

Well now, what can we say about this supplement? After taking an exhaustive look at Biphedadrene, we reached a decision. There are some positives, like the favorable BBB rating and the money-back guarantee, but we have doubts about recommending it because of the lack of scientific research supporting weight-loss claims. Plus, there is limited information about the company and some customer reviews are less than stellar.

If you’d like to lose the fat, we recommend going with a product delivering good results and a great price. It’s also important to choose a supplement with no reported side effects.

Among the best products we’ve seen in 2016 is one called Leptigen. The four-ingredient proprietary blend, has been shown in studies to help ignite metabolism and promote fat loss. There’s no talk about negative side effects and reviews on the web show that people are seeing exceptional results.

Also, the company behind Leptigen is so confident in the supplement, they’re offering a Special Trial Offer, which is a good choice.

Learn More About Leptigen »
GD Star Rating

How Does Biphedadrene Compare?

Previous Biphedadrene Review (Updated November 5, 2014):

What You Should Know

Click Here To See Our Highest Rated Review

Biphedadrene is a weight loss pill on that has made a miraculous return to the market in recent months. The product apparently disappeared for a while due to an “overwhelming demand” for it on shelves. If you are looking for a product to help you burn fat and suppress your appetite while you are following a diet and exercise routine to help you reach your weight loss goals even faster, read this review to find out how this product compares to others on the market today.

List of Ingredients

Not available.

Product Features

Biphedadrene does not provide a full ingredient listing on their website to help people analyze what they are getting before they buy it. They advertise it to be an amphetamine like compound, which means it will boost your metabolism to help you burn more fat and suppress your appetite, but it could have some side effects, such as insomnia, increased blood pressure and heart rate, and jitters. There is an extreme warning listed on the product, that says you should use caution while using this product as part of a balanced diet and exercise routine. While we do like that it promotes a healthy diet and exercise program, we tend to shy away from it because it indicates it may not be safe. A 60 capsule 15 day supply of this supplement will cost you $75 plus shipping and handling costs, where a 30 day supply will cost you $135. A 60 day supply will cost you $270, and give you an additional month’s supply for free, thus saving you $135.

See Our Featured


  • Biphedadrene has ingredients that will help you burn fat and suppress the appetite.
  • This product seems like it has the potential to have very negative side effects.


  • Biphedadrene is an expensive product for many people.
  • This product does not provide a free trial.
  • There is not a full list of ingredients available for review.
  • We are not able to find any evidence of clinical research to support this product.
  • There are no customer testimonials to support this product.


Biphedadrene may very well produce weight loss results, but individual results will vary based on the type of diet followed, the amount of exercise you do, and the overall amount of weight you have to lose. Given that we are not able to closely examine the ingredient list, and there is an extreme word of caution right there on the product packaging, we advise you to proceed with caution when using this supplement. It is definitely not safe for women who are pregnant, nursing, or trying to become pregnant. It is not safe for children under the age of 18, and likely is not a good option for those who have heart or other health conditions.

Biphedadrene Questions & Answers:

We refined hundreds of user comments about Biphedadrene into this helpful FAQ.

What are the side effects of Biphedadrene?

The potential Biphedadrene side effects may include jitteriness, nervousness, sleeplessness, muscle spasms, irritability, anxiety, upset stomach, nausea, increased heart palpitations and vomiting, according to some people who’ve tried it.

What are the ingredients in Biphedadrene?

Biphedadrene ingredients are trimethylxanthine, caffeine, α-phenylethylamine, β-phenylethylamine, phenethylamine, theobromine, microcrysalline cellulose, stearic acid, magnesium stearate, silicon dioxide, croscarmellose sodium, polyvinyl alcohol, polyethylene glycol, erythrosine aluminum lake, talc, titanium dioxide, fd&c blue #1 aluminum lake, fd&c #2 carmine aluminum lake, ilex paraguariensis, guarana, methylxanthine, tumera, capsaicin, seratonin, l-dopa, gelatin, rice flour, titanium dioxide, fd&c yellow #5 and fd&c yellow #6.

Does Biphedadrene work?

There’s no science to back the claims that Biphedadrene is an effective weight-loss supplement. There are studies into caffeine, but that is found everywhere.

You may want to consider replacing Biphedadrene with a supplement like Leptigen, which is made with clinically tested ingredients.

How much does Biphedadrene cost?

Biphedadrene costs $135 for a 60-day supply.

How should I take Biphedadrene?

You should take one purple and one yellow Biphedadrene capsule prior to your main meal. Each box contains a 60-day supply. The company recommends not exceeding four capsules in a 24-hour period.

Can I take Biphedadrene if I have a health condition?

Women who are pregnant or nursing, those taking prescription medications, those under 18 years of age and people with health conditions should contact a physician before using a weight-loss supplement, including Biphedadrene.

What do users like about Biphedadrene?

Some users liked that Biphedadrene was available on the official website.

What do users NOT like about Biphedadrene?

We found that users didn’t like the high price tag on Biphedadrene and the side effects.

How do I contact the Biphedadrene customer service department?

You can contact the Biphedadrene customer service department by mailing letters to BiphedAdrene 5742 West Harold Gatty Dr. Salt Lake City, UT 84116, calling a representative at 1-800-648-5642 or by using the customer feedback.

Can I still drink coffee on Biphedadrene?

No, you can’t drink coffee on Biphedadrene. The company recommends not consuming additional caffeine while taking this supplement.

How much caffeine does Biphedadrene contain?

Each serving of Biphedadrene contains 260mg of caffeine.

Does Biphedadrene come with a guarantee?

Yes, Biphedadrene comes with a guarantee. You have 30 days to return the supplement for a full refund.

Do you know of any special deals or discounts on Biphedadrene?

The only mention of a special deal or discount is if you purchase two boxes of Biphedadrene. You will save $135 on your purchase. However, our readers have been going off the chain taking advantage of Leptigen’s Special Trial Offer, which is just the cost of shipping and handling. Click here to give it a go.

Biphedadrene Ingredients:

We dug deep into the Biphedadrene ingredients to give you the details you need.

Yerba Mate Extract

Yerba mate is a plant, and the leaves are used to make the extract, which is used in a number of medicinal applications. In Brazil and Argentina, it is used to make a popular tea.

What is it Supposed to Do?

According to WebMD, yerba mate is used “a stimulant to relieve mental and physical tiredness (fatigue), as well as chronic fatigue syndrome (CFS). It is also used for heart-related complaints including heart failure, irregular heartbeat, and low blood pressure. Some people use mate to improve mood and depression; to relieve headache and joint pains; to treat urinary tract infections (UTIs), and bladder and kidney stones; for weight loss; and as a laxative.”

Clinical Research

According to a study published in Medicinal and Aromatic Plant Science and Biotechnology, “Yerba mate has been shown to inhibit the formation of advanced glycation end products (AGEs), with an effect comparable to that of two pharmaceutical grade AGE inhibitor drugs.”

When it comes to choosing a weight-loss supplement, clinical research is vital. You may want to take a look at a product like Leptigen, which is formulated with 100% clinically tested ingredients.


A chemical byproduct of the L-Tryptophan amino acid, this is also produced commercially, using the seeds of an African plant.

What is it Supposed to Do?

According to WebMD, “It works in the brain and central nervous system to increase serotonin. This chemical can affect sleep, appetite, temperature, sexual behavior, and pain sensation.” It is used for sleep disorders, anxiety and depression, migraine and tension headaches, obesity, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), and attention deficit hyperactivity disorder (ADHD).

Clinical Research

According to a study published in the American Journal of Clinical Nutrition “A reduction in carbohydrate intake and a consistent presence of early satiety were also found. These findings together with the good tolerance observed suggest that 5-HTP may be safely used to treat obesity.”

Damiana Leaf Extract

Damiana is a wild plant that grows in parts of Mexico, Central America, and the West Indies. The leaves and stems are used to make medicine. Historically, it was used mostly as an aphrodisiac, to increase libido.

What is it Supposed to Do?

We found information that said damiana is used for “headache, bedwetting, depression, nervous stomach, and constipation; for prevention and treatment of sexual problems; boosting and maintaining mental and physical stamina.”

Clinical Research

According to a study published in the Journal of Human Nutrition and Dietetics, Damaina may help with weight-loss. “The herbal preparation, YGD capsules, significantly delayed gastric emptying, reduced the time to perceived gastric fullness and induced significant weight loss over 45 days in overweight patients treated in a primary health care context.” However, the supplement used in the study combined damiana with yerba mate and guarana.


Caffeine is a stimulant found in coffee, tea, and soda. It can also be found in supplement form.

What is it Supposed to Do?

Caffeine is supposed to increase mental alertness and boost metabolism.

Arbutin Extract

Also known as bearberry extract, this is a natural skin lightener.

What is it Supposed to Do?

By reducing melanin production, this extract lightens the skin. It is used to treat age spots, freckles, sun spots, and can help even a blotchy skin tone.


Phenylethylamine is a chemical that occurs naturally within the body. It can also be made in a laboratory.

What is it Supposed to Do?

Phenylethylamine is supposed to improve athletic performance, help depression, help weight-loss, and improve mood and attention. It is not suggested in people who have a mental condition of any kind. Experts also agree that it can interfere with surgery.


Methylantine is a caffeine compound.

What is it Supposed to Do?

Methylantine is supposed to increase mental alertness and boost metabolism.

Cayenne Powder

Made from the red cayenne chili pepper, this adds spicy heat to food.

What is it Supposed to Do?

Cayenne pepper is supposed to boost metabolism.

Cutch Tree Extract

This comes from the seeds and bark of an Asian tree.

What is it Supposed to Do?

The product labeling suggests this is supposed to boost serotonin levels, but we found no clinical evidence to support the claim.


This is a precursor to the dopamine neurotransmitter responsible for a good mood. It is derived from the velvet bean, which grows in Africa, India, and the Caribbean.

What is it Supposed to Do?

L-Dopa is supposed to help elevate mood.


This is a chemical found in chocolate. Dark chocolate has more of this chemical than milk chocolate.

What is it Supposed to Do?

It is supposed to produce a stimulant effect similar to caffeine.

Is There Anything Out There That TRULY Works?

If you’re looking for something that fits the bill, we have one for you. Leptigen, which is formulated with ingredients that HAVE been clinically tested, may be a good option. All customers can take advantage of a Special Trial Offer. Click here to give it a shot.

24 User Reviews About Biphedadrene

Leave comments below
  • 1

    $135 for nothing…
    Been taking this 3x a day for 2 weeks….gained 4 pounds and all I want to do is sleep!!! What a rip off!!!😬😬😬


  • 2

    i just started taking biphedarene 2 days ago.i need to lose 80 pounds. i’m going to be pissed if this doesn’t work. i paid 100.00 at gnc for this. i pray it works without giving me headaches.


  • 3

    This is my third day taking the pills and I’m seriously considering calling it quits. You feel the energy boosts after 15 minutes which is great. However, sleep has been difficult and now my symptoms include my limbs tingling (like when circulation suddenly rushes through) and my fingers started moving involuntarily for 5 minutes. I’m 22 years old 5′ 7″ and 200lb. I’m going back to gnc to return this, it’s not worth my health


  • 4
    Your LisaName

    I would like to know if you can take this if you are on medication. Thanks Lisa Anderson


    Cameron (Editor)

    Hi, Lisa. Use caution if you are on blood pressure medication. Ask you doctor if this formula would interfere with your prescriptions.


  • 5

    So far I would like to say that these pills work. I mean as long as you’re taking as directed you shouldnt have a problem. I started taking these two days ago and I’m already seeing a difference in my appetite, weight, and even my mood. I am not wanting to eat as much and I have lost like 3 pounds already. I went from 203 lbs. to 200 lbs. and it makes you energized and wanting to do something all day. Honestly I’ve never felt better about myself than I do now. I’m hoping I don’t have any reactions to the Biphederene but you never know because it really doesn’t help that they won’t give out all the ingredients in this product. I wish the best for anyone who is taking it. I am 18 going on 19 and I take the pills once daily and eat portion sized meals 3 times a day and I also try to exercise more than an hour a day. It seems to be helping me so I would probably recommend it.


  • 6
    Sonja Roche

    I just bought biphedadrene and I will be starting to work in the hospital here but I didn’t want to show up dirty on a drug test because of it. BUt I seriously need to lose about 90-100 lbs. does anybody know if this could happen if I start taking biphedadrene before my drug test


    Stephen (Editor)

    We’ve not encountered reports like this for Biphedadrene.


  • 7

    I was introduced to biphedadrene by my roommate she gave me 40 pills (20 purple and 20 yellow) I lost 30 lbs in a month. I look so good. It’s not just taking the pills that will get you results you need to diet and exercise. I was hitting the gym 6 days a week for about 3-4 hours at a time. I was also running every morning. My diet was poor not because I was eating bad food but because I wasn’t eating enough to give my body the protein it needed for my muscles with all that work I was doing. Negative side of effect for sure is my insomnia. I can seem to be able to sleep for a couple nights and then one day I’m so exhausted I just crash sleeping for hours in the middle of the day. But I go to the gym late around 10pm and leave at 2 or 3 am. I stopped taking them for a couple months but just bought a new box a couple days ago. I just take the pills right before I work out once a day that’s it so they last me a good amount of time. I’m a college student living on my own paying my own bills with a 2 jobs and I can afford them. They’re worth it!!! But give it 2 weeks to start seeing results and a month for others to see it. Exercise and diet or else you won’t progress as dramatically


    Your Name

    Lost 30 lbs in a month. Ok!


  • 8
    virginia weaver

    I got my box of biphedadren on may 24th 2013 and have been taking it like it said but I would like to know how long it will be before I start to see weight loss.. I did not get any book telling me what to expect from taking these diet pill’s.



    I took this for I think two months with moderate exercise and diet. I didn’t take it seriously but by the end of two months I had lost alot of weight. I started to notice my jeans very loose they weren’t holding onto my body anymore, everybody was in shock and when I got on the scale, I was weighing 124lbs from my usual 143lbs. Love it


  • 9
    Evy Vaudrin

    This is my first day trying BiphedAdrene. Wth all the bad reviews I’ve seen from a few websites, it almost completely discouraged me from getting this product, but i have to say that i’m loving it so far, after taking the first dose yesterday morning it started to work in 15 mins! i felt the rush of energy that made me want to get out of my pj’s and exercise, instead of lounge around sitting in front of the tv watching re-runs of gossip girl. I’m 5’6 and 100lbs over weight and i’ve been wanting to lose it but had no energy and always felt down, but i feel great! which contributes to me want to be more active and is definately a plus. My appetite has decreased and im not constantly thinking about food, i did noticed that i’ve been super thirsty and have been drinking more water which i normally don’t do, so that’s another plus. i started this with my sis-in-law and she feels the same, that this is working! the only downfall about it is that its very costly, but i’m glad i can purchase it through Amazon and i can take advantage of the prime thing and get the shipping for free and that they are super quick too! so heres’s my 1 vs 1000 great review!! so i’d say give it a try and if doesn’t work for you.. then move on!



    drink more water


  • 10

    I’ve been on it 3 days. No negative side effects. Lost 4 lbs in that amount of time and I’m a lot more energized and seemed to put me in a more positive mood. I take it twice a day and I have zero problem sleeping. I would recommend it so far.


  • 11

    did you lose any weight or did the serious side effects made you quit before you could lose weight



    Carla Istarted taking around oct 6 2012 I weighed myself toward mid end of dec n had lost 15 pounds as I stated before if it makes u jittery take half purple n whole yellow n eat within 15 min of taking it. Also limit caffeine intake . I called them n got that info from an operator and it worked.


  • 12

    this pill is serious hell when i take it i feel like i’m about to die!!!! my heart starts palpitating, i start getting shortness of breath! and worst of all while i’m sleeping i stop breathing at times waking up with rapid heart beating. i cut my intake down to one serving per a day. i’m so freaked out. now i’ve quit!!


  • 13
    Deana Payne

    Hello im Deana Payne i would love to here from some one thats tryed this becouse im a 47 year old femaleand im 5ft/4in tall and kind of top heavy but between us i weight 178lb thats a lot im taking thynoid meds and more then a few outhers dut i still need some thing to help me get fid of about 35-40lbs around ther


    Brandy Bueno

    Deana, I am 40 yes old & we are the same height & weight. I just keep getting bigger! I have no energy therefore I don’t exercise. My question for you is have you tried the Biphedadrene yet? I don’t want to waste more money on more lies. Please let me know what you think




    Not a good idea on thyroid meds. U have to be really careful with strong diet pills and thyroid. My opinion, not worth the risk for you. Try to find something more natural.


  • 14

    Would biphedadrene cause a positive for amphetamine on court ordered random UA’s or mouth swab?



    I would hope not, considering that would make it a “controlled substance” which would be a schedule 2 narcotic.


    Evy Vaudrin

    i work in a clinic and have access to urine drug screening tests and haven’t come positive for amphetamine.


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