Updated: 11/17/2015 - Sponsored by Leptigen

DNPX Review - Does This Fat Burner Work? Are ineffectiveness and side effects deal breakers?

Editor's Review: 3.5 / 5.0

dnpx-product-image97% of dieters just want a product that works. Yeah, we can’t figure out the other 3%, either. There’s a lot of curiosity surrounding DNPX, so we dug deep into the ingredients, side effects, clinical research and customer support. We took the time to read hundreds of comments and reviews. We then summarized and refined to give you the info you need.

EDITOR'S TIP: Substitute DNPX with a proven fat burner such as Leptigen for better results.

What You Need to Know

First off, DNPX is a fat burner containing 1,3-dimethylamylamine, caffeine, tannins, vasicinone, casicine, vasicinol, phytoterols, mucins, yohimbine, 3,5-diiodo-l-thyronine, white willow bark extract and black tea extract. The recommended serving is one capsule per day, which supposedly increases weight-loss. One of the benefits is ease of use.

The supplement, introduced as a fat burner in 2010 by Pro Supps, includes a few natural ingredients, a good choice. Customers can purchase the product on the official website and through other online stores. We do like that we found some positive comments, but read on…

Ineffectiveness – “Does it Work?”

The first problem we have is that DNPX ingredients don’t work, according to users. “Dieters take fat burners typically to speed up weight-loss,” said our Research Editor. “If you take the time and money to try out a new product and it doesn’t work, why go back for more of the same?”

“Well crap, took 1 cap this morning at 9:00 on an empty stomach. Felt nothing, what-so-ever. No raise in body temp, no raise in heart rate, nothing,” said a consumer.

“More expensive and less effective than real DNP,” said a customer.

Scroll below for one of the best products we’ve seen in 2015.

FDA Investigation

On April of 2015, Pro Supps was investigated by the Food and Drug Administration. The company had supplements on the premises that contained more of an active ingredient than the label reported. The FDA has also banned DMAA from products due to potential side effects. DNPX continues to use it in the formula.

Side Effects – “Feeling Bad!”

According to numerous customer comments, DNPX side effects are a problem. “I made the mistake of taking it before cardio and had to stop after 10 minutes on the trail and lay down to get my heart rate down,” says one comment.

“I had a 30 min long hot flash, pounding head ache and was shaking,” reported a user.

“After finishing the bottle (30 day supply) I felt extremely tired and fatigued. The fatigue was so bad that the only thing I can compare it to is like when you take a sleeping pill – I felt drugged,” said a dieter.

Our research shows that if something about a supplement is deemed troublesome, like adverse side effects, the likelihood of long-term success is off the table. If DNPX causes negative reactions, there is a call for concern.

The Science – “Evidence?”

The official website makes the case that DNPX will improve focus, eliminate fat and suppress appetite, but we can’t find any published clinical studies linking the formula to weight-loss. We found an FDA page warning dieters about the dangers of using DMAA, an ingredient in this product. For us at DietSpotlight, locating scientific research supporting claims is imperative. If a company can’t produce the science, we don’t see the purpose.

The Bottom Line – Does DNPX Work?

Well, ladies and gentlemen, what do we say on this one? After thoroughly digging into DNPX, we’ve come to a conclusion. There are some positives, like we found a few supportive customer comments and the favorable BBB rating, but we have trouble getting behind it because the weight-loss claims are not supported by published clinical research. Plus, we’re concerned about the FDA findings, ineffectiveness and negative reactions.

If you’d like to shed those extra pounds, we recommend going with a product that’s proven to give you the weight-loss results you desire, without having to worry about harmful side effects.

Among the best products we’ve seen in 2015 is one called Leptigen. The formula contains a four-ingredient proprietary blend, which has been shown in published scientific studies to help speed up fat loss and ignite metabolism. There’s no one talking about negative side effects and reviews say dieters are seeing great results.

The makers of Leptigen, showing confidence in the supplement, are offering a Special Trial Offer, which is a good choice.

Learn More About Leptigen »
GD Star Rating

How Does DNPX Compare?

Previous DNPX Review (Updated May 23, 2014):

What You Should Know

Click Here To See Our Highest Rated Review

DNPX is a thermogenic supplement designed for bodybuilders. Bodybuilders tend to take higher concentrations of stimulants like caffeine, which means the supplements designed for bodybuilders are often stronger than those designed for the average dieter. In some cases, bodybuilding supplement can be dangerous for the average dieter. Check the label of all stimulant supplements before choosing to start a new fat burner. Learn about each ingredient and make sure that none of the ingredients could cause negative side effects of interfere with current medications or illnesses.

DNPX contains caffeine, which we expected, but there is also quite the proprietary blend in the mix. The proprietary blend includes some dangerous ingredients that may not be safe for all dieters. We suggest dieters choose a different product that does not contain ingredients with potentially life-threatening side effects.

List of Ingredients


  • Caffeine
  • 3, 5-Diiodo-L-Thyronine
  • Tannins
  • Vasicinone
  • Casicine
  • Casicinol
  • Phytosterols
  • Mucins
  • White Willow
  • O-Methoxy Phenylethylamine
  • Beta Phenylethylamine
  • 4-Hydroxyphenylethylamine
  • N-Dimethyl-Hydroxyphenylethylamine
  • Black Tea
  • Cocoa Extract
  • Thiamine Propyl Disulfide
  • Thiamine Disulfide
  • Thiamine Tetrahydrofurfuryl Disulfide
  • 5-HTP
  • Alpha Yohimbine HCL

Product Features

DNPX is not a diet supplement that we'd suggest for the dieter looking for a supplement they can take to boost metabolism and lose weight. The ingredient list is packed with stimulants and mood-boosters. We did not notice any ingredients that made this supplement different from other fat burners or unique to the bodybuilding industry, but we did notice some dangerous ingredients.

First, there is too much caffeine per serving. Taking 200 mg of caffeine is not necessary to increase energy and metabolism. Paired with the huge dose of caffeine is PEA - a mood booster that works similarly to some street drugs to boost mood. If DNPA removed this ingredient the formula would be rather good.

Black tea and 3, 5-Diiodo are both proven to boost metabolism and increase weight loss when taken with a reduced calorie diet and exercise program.

The product description for DNPX mentions the formula contains ephedra. We did not see ephedra on the ingredient list. Ephedra is banned and regulated in the US. If this supplement contains ephedra it is either illegal or it contains a legal extract of ephedra.

See Our Featured


  • All of the ingredients are listed online.
  • The supplement contains multiple proven ingredients.


  • There is too much caffeine in the formula.
  • PEA alters mood and may affect how prescription drugs work.


DNPX claims to be a bodybuilding fat burner, but that's not what we see in the product description. There is a ton of caffeine and a few proven ingredients packed with PEA, a potentially dangerous ingredient. We don't particularly like the fact that this supplement could cause negative side effects for dieters with mental health issues.

5 User Reviews About DNPX

Leave comments below
  • 1

    Does this has Amp-Citrate in it?…


  • 2
    Allegra Renee

    I personally really like the contributor posts but I also love reading your more personal posts too so I think the balance is just right! It’s really down to what you see this blog evolving into at the end of the day and that’s a tough decision. You really are one of the view bloggers who I keep coming back to…


  • 3
    Chiara Walther

    I loved DNPX so much i’ve lost 7kg by taking every day one pill.
    (My partner used it too and my friend too so the box was empty and I haven’t finished my diet)
    I wonder why I couldn’t buy it anymore, it’s so hard without it, and I’m a student and I’m often stressed and then I would eat something but DNPX made that I even forget that I could eat something, I could work without thinking ‘oh something to eat now would be great’ in the gym I had everywhere progress and now the progress is away, I’m so sad, I gained weight and lost muscles.
    DNPX is the best supplement! My mother is a pharmacist and she made herself sooo many good diet supplements but she said this one is the best she ever tried!
    Tell me please that I could buy more of it, because I love it.

    (I’m sorry for my really bad english I’m not very good in the english classes, but I hope you understand my problem)

    Best wishes
    Chiara Walther



    Hi I don’t where u from but we sell at Sunshine Health Food store in Tupelo,MS


  • 4

    200 mg of caffeine is rather light in my opinion. It’s less than a cup of Starbucks coffee.


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