Updated: 04/26/2016 - Website operated by Leptigen

Phentremine Review - Does This Meal Replacement System Work? Are cost and harmful side effects deal breakers?

Editor's Review: 3.5 / 5.0
Phentremine Review

Why is it that so few diet products are backed by science? Let’s find out if Phentremine is one of the good ones. This supplement has been billed as an alternative to Phentermine, which is a medication that requires a prescription. We did an in-depth review on Phentremine looking at the ingredients, side effects, customer service and clinical research. We also looked at the consumer experiences on dozens of websites and compiled and refined to give you the bottom line.

EDITOR'S TIP: Combine Phentremine with a proven fat burner such as Leptigen for better results.

What You Need to Know

To start, Phentremine contains caffeine, synephrine, phenylalanine, theobromine and copper sulfate, in a proprietary blend designed to help you lose weight quickly. We did not find any information on how often you take the supplement, but we suspect it is once or twice daily. The capsules are convenient and can be taken on the go.

Phentremine has been around since 2006, so they’re still fairly new to the industry, but it seems to have some staying power. It can be purchased from a variety of sources online without a prescription and there are some positive reviews claiming significant weight-loss within just a few months, but read on…

Cost– “Yee-Ouch?”

Our first issue with Phentremine ingredients is the cost. The first 30 day supply is only $65-80, but it reportedly signs you up for automatic renewal, which bills your card $80 a month until you cancel it. “There are many complaints online about the auto-subscription of Phentremine, which re-orders and charges your credit card each month,” said our Research Editor. “Many reviews claim that the auto-subscription is difficult to cancel and impossible to get a refund for.”

“They charged me $80 extra, and I didn’t even finish the ‘free’ trial period,” said one disgruntled user.

“I’m not sure if these pills work or not, but the auto-subscription has me worried. Stay far, far away from Phentremine,” said another.

Scroll below for one of the best products we’ve seen over the last year.

Harmful Side Effects – “Troublesome”

The next glaring concern was the potential for adverse reactions associated with Phentremine. “I was going to try Phentremine, but the long list of side effects make this an easy decision,” said one customer.

“My sister recently started taking Phentremine, and she’s now in the hospital with severe heart palpitations,” said another.

Throughout our research into diet supplements and weight-loss products, we’ve learned that any time there is a negative aspect (painful exercise, negative side effects, cost, taste etc.) the likelihood of long-term success is minimal. If Phentremine really does have a long list of common adverse reactions, this could make it difficult for many customers to lose weight and keep it off.

Is There Any Science?

The lack of science behind Phentremine is concerning. It seems as though the manufacturers hope that it will be confused with Phentermine and users will buy their product by mistake. The ingredients they use have some scientific research backing their effectiveness, but the formula that Phentremine uses has never been studied and proven to aid in safe, effective weight-loss. Here at DietSpotlight, we think it’s important to have published data behind your claims, so without proof what they’re saying is true, we can’t trust it.

The Bottom Line – Does Phentremine Work?

So, we’re at the end of this one – ready for the final take? There was some initial optimism when reviewing Phentremine. The product is easy to purchase, has some positive reviews and has been around for almost 10 years, but that’s where the positives end. Because of the lack of scientific research behind Phentremine’s claims, we have reservations recommending it as a weight-loss supplement. We also have serious concerns about the long list of side effects and the company’s unethical practice of auto-subscribing customers.

If you’d like a product that will help you lose weight without the high price tag or lifetime of side effects, we suggest one that supports weight-loss with an ingredient list that is backed by published clinical studies.

Among the best products we’ve seen in 2015 is one called Leptigen. This innovative, proprietary blend of four ingredients has been supported by numerous scientific studies and has been used in published clinical trials to show its effectiveness at helping boost metabolism and spark fat loss. Users have seen great results with Leptigen without the side effects and it’s affordable and convenient for any lifestyle.

Leptigen’s makers are so confident that you’ll love their product, that they’re currently offering a Special Trial Offer for new customers.

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How Does Phentremine Compare?

Previous Phentremine Review (Updated January 1, 1970):

What You Should Know

Click Here To See Our Highest Rated Review

As a dieter in this day and age, there is a lot to learn before simply acquiring the first weight loss pill, shake, or supplement you encounter. After all, you certainly want a product that assists you with fat reduction, but is harmless to your body as well. The good news is there are plenty to select from. One of these dietary supplements is Phentremine. It may be able to help some adults lose that extra five or fifteen pounds in a timely fashion.

Among the ingredients offered in Phentremine, you will find L-Phenylalanine (regulates the user’s blood sugar levels), Theorbromine (speeds up the metabolism and increases thermo genesis), Caffeine (boosts energy levels), and Synephrine (helps by suppressing hunger). Unfortunately there are no testimonials presented on the official website to support Phentremine as an effective diet supplement.

List of Ingredients

A Proprietary Blend of L-Phenylalanine, Theorbromine, Caffeine, Synephrine, and Copper Sulfate.

Product Features

Phentremine is a dietary supplement that is claimed to assist dieters with reaching their weight loss goals. Unlike some other formulas for fat reduction on the market today, this one appears to be primarily geared toward women. Not only does it aim to suppress hunger and burn off unwanted fat and calories, but it additionally works to heighten thermo genesis, boost energy levels, and increase the user’s metabolism. Phentremine does not require a prescription, and it is available online via an official website. A 30-day supply sells for $64.99. There are no returns accepted after 30 days of purchase, and there is no money-back guarantee for Phentremine, unless the bottle is unopened. Fortunately there is a helpful FAQ section provided on the primary website to assist dieters.

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  • This diet drug may increase the user’s energy levels.
  • Phentremine may assist with mental awareness and focus.


  • There are several warnings posted online pertaining to Phentremine.
  • There is no satisfaction guarantee provided with this diet product.
  • The cost is pretty high at $65.
  • Some users may experience upset stomach, headache and dizziness.
  • No research is provided to support weight loss claims made about Phentremine.


It can be tricky locating the right diet product for real weight reduction. This is why it is imperative to do your research in the beginning. As far as Phentremine is concerned, there are not many reasons to choose this diet product. While it does endeavor to burn off fat and improve thermo genesis, there is really no data to support these claims. Furthermore, there is no money-back guarantee or refund option with Phentremine if you open it and try it. On the bright side, many other weight loss supplements out there today do come with a satisfaction guarantee.

Phentremine Ingredients:

We dug deep into the Phentremine ingredients in order to provide the details you need.

Vitamin B-12

Also called cyanocobalamin, this is a vitamin that’s found in foods like fish, dairy and meat products. Vitamin B-12 plays an important role in the metabolism of proteins. Also, it helps the body produce red blood cells, which is crucial for overall health.

What is it Supposed to Do?

Firstly, there are many supplements and multivitamins that provide vitamin B-12. Typically when it’s used in diet products, it’s claimed to increase energy levels and help with weight-loss. However, there is really no evidence to support this.

Clinical Research

According to WebMD, “vitamin B12 is effective when it comes to treating conditions like pernicious anemia.” It is administered through injections or by mouth. However, there is no scientific research that suggests it will help with weight-loss.

Clinical testing is crucial when it comes to selecting the right diet product. Therefore you may want to check out a product like Leptigen. This supplement actually contains clinically tested ingredients.

Chromium Picolinate

Chromium picolinate is often used as an alternative medicine. It’s essentially a supplemental form of chromium, the mineral, which is important for food digestion. You will find this ingredient in all sorts of diet products and supplements available in stores and online.

What is it Supposed to Do?

Well, it’s intended to aid with weight-loss and type 2 diabetes. This ingredient can help manage blood glucose levels by enhancing insulin activity. It may reduce appetite. Also, it assists the body with metabolizing carbohydrates.

Clinical Research

A number of clinical studies have been conducted with chromium. Many of these concern diabetes and/or weight-loss effects. In fact, according to AHC Media, one study reported that people experienced, “Increased fat-free body mass and decreased body fat after chromium supplementation.”

Hoodia Gordonii

There are many natural herbs used in over-the-counter diet pills. Hoodia gordonii, for instance, is one of them. It’s a cactus-like plant, and it grows in the Kalahari Desert of South Africa. The extract from this cactus is often found in weight-loss supplements available online.

What is it Supposed to Do?

Hoodia gordonii contains an active molecule called P57. This component is claimed to suppress appetite. It essentially works by tricking the brain into believing the stomach is full. This in turn aids with weight-loss.

Clinical Research

There have been some clinical trials done with hoodia gordonii extract. For instance, the National Institutes of Health conducted a weight-loss study. It showed that, “energy intakes and body weights did not differ significantly between the hoodia gordonii and placebo-treatment groups.” While this cactus extract did not help with weight reduction, it did not cause any side effects, either.

Is There Anything Out There That We Think TRULY Works?

We have noticed a supplement that shows real promise. Leptigen, which is formulated with clinically tested ingredients, is a good option. All customers can take advantage of a Special Trial Offer, currently available. Click here to give it a try.

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