Thyrene Review

Editor's Review: 3.5 / 5.0

What You Should Know

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Thyrene is a product from Metabolic Nutrition that claims to boost fat loss by stimulating the thyroid. There are no stimulants in this formula, which could mean no fat loss or increased metabolism. We are not fond of thyroid stimulating supplements that make huge claims without any support for those claims. We know that 3, 5 Diido-L-Thyronine has some clinical support, but Metabolic Nutrition fails to use that support to validate this supplement.

Dieters looking to boost weight loss with a safe and effective supplement may wish to choose a different product. We could find no clinical studies supporting this supplement and one of the ingredients is available only from Metabolic Nutrition with no information about what it is or what it does listed on the website.

List of Ingredients


  • Folate
  • Vitamin B12
  • Calcium
  • Iodine
  • Potassium
  • Vitamin B6
  • Phosphorus
  • L-Tyrosine
  • Coleus Forskohlii
  • Guggulsterones
  • Di Potassium Phosphate
  • Calcium Phosphate
  • Sodium Phosphate
  • 3, 5 Diido-L-Thyronine
  • Kelp
  • Meridextrine

Product Features

Losing weight is about burning more calories than you consume. The thyroid plays an important role in the rate of your metabolism, but not many natural supplements have an effect on thyroid function, despite the outrageous claims of some companies. Thyrene makes those same outrageous claims, but at least one ingredient has been tested with positive weight loss results – 3, 5 Diido-L-Thyronine. Metabolic Nutrition does not list the available clinical support for this ingredient, however. That could be because the weight loss associated with the ingredient is not that remarkable.

The other ingredients in the Thyrene formula are commonly found in other weight loss supplements. None of them have a significant impact on metabolism as none have stimulant properties.

The instructions for taking the supplement are more confusing than some other products. The dieter is supposed to start off by taking one capsule three times a day. Then, after gauging how the body reacts, up the dose to two capsules three times a day. There is no description of the possible feelings the dieter could have or how to gauge if the supplement is too strong and since there are no stimulant ingredients we’re unsure how the dieter is supposed to know when to up the dose.

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  • We easily found the ingredients online.
  • No stimulants so the supplement can be taken multiple times a day.


  • The dieter is left to choose when to take the maximum dose.
  • No stimulants means no increase in metabolism.
  • No appetite suppressants included in the formula.


Thyrene could be considered a safe supplement, but there is one problem. Meridextrine is an unknown ingredient found in most Metabolic Nutrition supplements. We’ve said throughout that this supplement contains no stimulants, but that may not be completely true. There is a chance that Meridextrine is a stimulant and if that is the case, some dieters may feel negative side effects.

GD Star Rating

3 User Reviews About Thyrene
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  • 1

    You totally jacked the instructions. Take one tablet for the first 3 days not 1 tablet 3 times a day!


  • 2

    I have been an avid fan of Cellucor (although I know its expensive) I have been using CLK & Super HD (8 weeks on 3 weeks off) for about 2 years!… However, after I was given a sample of Synadrex (*The New Formula is amazing!!) about a week ago I have decided to start a new stack using Synadrex, Thyrene, Phenolox, & a simple Multi-vitamin (and cellucor CLK).
    My plan is to alternate Synadrex and Phenolox (Synadrex on Monday and Phenolox on Tuesday *1pill a day) then add Thyrene after a week (*1pill a day) and continue taking CLK (up to 6 pills a day but I usually only take 3)
    One thing people need to understand is that there are no miracle pills on the market… if there were, the government would paten it, classify it as a controlled substance and only give it to the soldiers in the army 😛 lol

    On a more serious note: (*I can not rate this product yet) As far as Thyrene goes…. states:
    Due to the strength of THYRENE, please assess your tolerance by initially taking only 1 capsule upon awakening for the first 3 days. After assessment, if effects last longer than 15 hours, consider altering dosage to every other day. With caution, you may increase up to 1 capsule in the AM and 1 capsule at Noon. DO NOT exceed more than 2 capsules daily or 12 hours prior to desired bedtime.
    Only Synedrex, Phenolox and Hydravax may be combined with THYRENE for a more customized weight loss solution. DO NOT combine with other non approved supplements or medications.


  • 3
    simone manoo

    on d first day i took one pill i started feeling pins sticking me through my skin y is tht an a pain in my stomach should i stop it


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