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Active-PK Review - 14 Things You Need to Know

Active-PK is a “revolutionary new formula designed to help you fight abdominal fat.” It claims to help you shed extra pounds through the process of AMPK activation; the so-called cellular “master switch.” There’s actually some science there, but does this formula have the correct dose of ingredients?

Our research team stepped in; tracking current studies on the effective ingredients. Most of the science cited on the Active-PK website indicates clinical results with higher doses than the Active-PK formula provides. Let’s see if Active-PK can live up to the promises.

Active-PK can be purchased through their Official Site.

Active-PK Readers: Noom is offering our readers a risk-free trial, for a limited time. Click here for more information!

What is Active-PK?

Active PK is a weight loss formula designed by LCR Health to fight against abdominal fat build-up. According to the manufacturer, Active PK’s goal is to help you feel healthier and stronger in your body (of course, while you lose the weight).

It attributes this weight-loss feature to a formula known as AMPK activation. Further research on AMPK reveals it’s an enzyme “warning” your body against storing fat. It, however, tells the body to make a useful conversion of the fat into energy. Hence the stronger-body result.

This means you get to kiss persistent fatigue and unsolicited cravings goodbye. You also get to throw your arms open to higher energy levels and, wait for it, a smaller waist circumference.

  • Biomedicine and Pharmacotherapy – There is tons of research on Berberine. There’s some indication that doses of 300mg and up can work on cholesterol and gut health in human results.
  • Obesity (Silver Spring) – With 12 weeks of supplementation, research shows reduced weight and BMI in study participants using gynostemma. The research states, “These results suggest that [gynostemma pentaphyllum] supplementation may be effective for treating obese individuals.”
  • DMSO: Targets and Therapy – “The current evidence suggests that quercetin intake did not show a notably favorable effect on weight loss.”

Active-PK Competitors

AMPK Activator
Beyond Tangy Tangerine

How Did Active PK Start?

Active-PK was designed and formulated by a team of biochemical and nutritional experts from the Los Angeles-based manufacturing company, LCR (Live Cell Research) Health. This team features one of America’s finest doctors in regenerative health, Dr. Rand McClain.

Along with his team, Dr. McClain created the Active-PK formula as a medium to help individuals achieve fast and realistic goals in weight loss. He aimed to develop a supplement not only helpful in the whole process of losing weight but also beneficial to the overall health at the cellular level.

Other LCR Health Products

  • Telegenesis
  • GP-Slim
  • Prime ATP
  • QL-5
  • Midogen
  • UltimateH2
  • Master Cell
  • Sirtogen
  • Active Stem
  • Advanced Joint Support
  • Pro Krill 1000

Active PK Claims

LCR Health claims that active-PK can help fight against abdominal fat for a healthier and stronger body from the information given on its website. It utilizes a formula activating the AMPK in the body to cut back on cravings, reduce fatigue, and clear foggy minds.

Male Extra claims

It also claims Active-PK provides a slimmer waistline with regular use.

LCR Health has also declared Active-PK safe, although it didn’t state to what degree it is secure. It is suitable for vegans, contains no caffeine or dairy products, and has doesn’t have synthetic additives.

Oh yeah, the website also had the clause “…third-party tested for safety and purity.” But don’t worry; we’ll take you through our findings so you can decide for yourself the veracity of these claims.

Active-PK also boasts a three-ingredient blend promoting weight loss. We think LCR’s strength lies in its components’ supposed power to do the weight loss job. Hence, it makes a proud offer of a 90-day full refund on every Active-PK supplement’s purchase. It is so confident in Active-PK’s efficacy that LCR Health offers a 90-day, 100% refund if you don’t see Active-PK results.

PXL ingredients


Active PK Ingredients

Active PK ingredients include:

  • Berberine
  • Gynostemma Pentaphyllum
  • Quercetin Dihydrate


The U.S. National Library of Medicine states that berberine is a chemical found in several kinds of plants.

According to Metabolism, “Berberine has been shown to regulate glucose and lipid metabolism in vitro and in vivo.”

Gynostemma Pentaphyllum

According to Alternative Therapies in Health and Medicine, gynostemma may have a role in weight loss.

Quercetin Dihydrate

According to the NCI, quercetin is a polyphenolic acid that can be found in multiple plant sources. Specifically, it can be found in onions, cherries, broccoli, and cherries, per Pharmacognosy Review

Nutrients found that quercetin can have beneficial effects on inflammation and immunity.


Does Active-PK Work?

Active PK doesn’t have scientific evidence to prove its efficacy. However, there’s research relating to Berberine, gynostemma pentaphyllum, and quercetin dihydrate. One may see the significant role AMPK plays in fat reduction and energy production in the body. Remember, results vary from person-to-person. Let’s see what results are supposed to look like.


Active PK Benefits and Results

LCR Health states Active-PK benefits include:

  • Energy boost
  • Decrease abdominal fat
  • Clear brain fog
  • Support a healthy body

Qsymia benefits

Active-PK Reviews

Active-PK reviews are telling us the supplement didn’t work for some. One of the complaints was related to the ineffectiveness of the supplement. However, the positive reports, which outnumber the negative ones, seem to put Active-PK in a good light.

One customer said she took Active-PK for ten days and saw a weight loss of 5 pounds with fat reductions in her arms, mid-section, chin, and neck and a significant improvement in her sleeping pattern – although not related to Active-PK.

Another customer said she lost a full waist size and 28 pounds in 3 months of using the weight loss supplement.

While another customer who happens to be on the big side said his cognitive functions became sharper, energy levels increased, and cravings dropped significantly. He said he didn’t see any significant weight loss but will continue with the product because of the other benefits he gained.

Details on Active PK and Weight Loss

Active-PK is primarily a weight loss pill claiming to take advantage of the body’s enzyme balance to induce weight loss via a natural and biochemical process. It is formulated with an AMPK activator to increase the AMPK levels in the body.

Prebiotics and weight loss

In turn, the AMPK increase helps break down fat, which then produces energy by speeding up the body’s fat breakdown.

What’s more? Clinical trials reveal how AMPK can slow down the rate of response to appetite. Thus, making dieting relatively easier as dieters can now take it slow on caloric intake.


How to Take Active PK

The manufacturer advises taking two capsules of Active-PK with a glass of water. Please note, you take Active-PK with or without food. The ingredients go to work around the clock as soon as the body digests the capsules.

Side Effects

Potential Active PK Side Effects

While there are no mentions of side effects from Active-PK, there’s a chance some may notice side effects from Active-PK ingredients, based on research on its ingredients from sources like the Journal of the American Heart Association.

Gynostemma Pentaphyllum

When taken in the short term (less than five months), all indications show Gynostemma Pentaphyllum is possibly safe when taken orally. Some users may experience:

  • Increased bowel movements
  • Nausea


As long as it is just for a short period, all indications point to Berberine being safe to apply to the skin or taken by mouth. Berberine warnings and precautions include:

  • Never give Berberine to newborns.
  • Avoid use if you are pregnant.
  • Avoid use if you are breastfeeding.

Quercetin Dihydrate

Quercetin is a plant pigment found in many well-known plants like green tea, onions, berries, and apples. You can also find it in red wine, Gingko Biloba, and St. John’s wort.

  • Headache
  • Nausea
  • Tingling with oral use

Any Active-PK Lawsuits or BBB Complaints?

LCR Health, the Active-PK creators, are accredited by the Better Business Bureau and have an A+ rating.

The company has 46 customer reviews and 20 complaints.

Active-PK Alternatives

Ultimately, when it comes to finding the right weight loss supplements, there are a million and one bottles of capsules on the market pining for your attention – each one with one reason or another why you should go for it.

We know the task of finding the right one may be nerve-grating and time-consuming, and honestly, we haven’t brought you permanent relief.

The best way to know if a particular weight loss supplement is right for you and will work for you is to check with your doctor and also give him or her a load down of your medical history.


Active-PK Pricing

  • 1 bottle: $89.95
  • 3 bottles: $242.85
  • 6 bottles: $455.70

What Users Are Saying

“Have to take first thing, preferably on empty stomach.- Since I’ve taken this product. I have found a difference when taking it and when I don’t. I have maintained my weight loss gains.”

“Didn’t noted any change after taking this product for one month, I think I paid a high price for nothing, HONEST.”

“I don’t buy this for weight loss although the first time I used it, I did lose weight. What I like about it is that it dropped my cholesterol 40 points, and it is good to help control your sugar, too. I am not diabetic, but although my sugar is still in the normal range, it was increasing some, and this got it back under 100. I do think it is too expensive, though.”

Bottom Line

The Bottom Line on Active-PK

Will Active-PK get rid of your excess body fat? Based on the active ingredients, there’s a chance you’ll see positive results. We like the formula, research supporting the claims, as well as positive customer experiences. There are no concerns with this one, considering all of the positive backing the supplement.

We’re living in a world where lifestyle changes are necessary for weight loss. But it can be extremely hard to lose weight with these types of changes without help. That’s where technology has brought us an answer research proves works.

Among the best weight-loss apps we’ve seen in years is Noom. Unlike so many others, Noom comes with human coaching, not just some advice thrown together off the internet. It also provides users with meal plans and exercise tracking, so you can stick with the changes for good.

Dietspotlight readers are currently able to sign up for a free trial offer of Noom just for reaching our site.

Learn More About Noom »
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What is an AMPK Activator?

The AMPK Activator switches on the Adenosine Monophosphate-Activated Protein Kinase. The enzyme works as the master regulating switch for the human body. An increase level of AMPK activity assists in the revitalization of aging cells. It also helps to further production of mitochondria and it prevents many factors damaging and tied to the aging process.

What is an AMPK gene?

An AMP activated protein kinase (AMPK) is 5′ and is also referred to as a 5′ adenosine monophosphate-activated protein kinase. It is an enzyme of the type EC, and it performs a vital function in the process of cellular energy homeostasis. It is comprised of three different proteins, or subunits, resulting in a working enzyme conserved from yeast all the way to humans.

What is the Active PK supplement?

Active-PK is a dietary supplement sold by LCR Health. This product claims to help promote AMPK activation.

What is Active PK used for?

Active-PK claims it can be used for boosting the metabolism, increasing energy, and reduce food cravings.

22 Active-PK Reviews

    M&H GRANT (Verified Purchase)

    First do you must commit to taking the capsules every morning. If you cannot commit to just that, then you probably will fail.
    ACTIVE PK, it works!!

  • keeping fingers crossed

    Have been taking for ten days now and have seen no results. Going to give it more time and hope to see some results.

    • Gerald

      Same here

    • Gerald

      Same here , no results

  • Debbie geritano

    Love it. Seen a real improvement after 2 months in my stomach area

    • Elio

      Go get that fat Debbie! Best Wishes

  • it works
    ken snavely (Verified Purchase)

    it works for me my second order 28 lbs and one full waist size in 3 months I’m sold I feel better every time I exercise

  • Ingredients
    J Northrop

    Is active pk gluten free?

    • Dan

      Yes states it on their website

  • I do not recommend
    Martha (Verified Purchase)

    Already taking it daily for a month , but my weight is not going down. I gained 2 pounds even thou I exercise regularly and eat healthy. I don’t recommend this product.

    • Victoria (Editor)

      Hi Martha! Have you looked into other fat burners? You might want to check out Dietspotlight Burn!

    • Elio

      My body, historically, replaces fat with water after awhile, and i see more weight… Then seemingly over night, i start losing the water, and tremendous amounts of weights coming off…

  • Rose (Verified Purchase)

    it did not work for me. Nothing, Nothing, for 3 months.

  • No Positive Results
    Bruce Tetreault (Verified Purchase)

    Not working for me. I have taken the product for almost 3 months and my weight is the same. I do not feel any increase in energy . Different people may get better results. I am planning to return the 3 empty bottles to see if the guarantee refund really works. I have given this product a fair chance.

  • Rose (Verified Purchase)

    I have been taking Active-Pk for about a month now. I started out with 2 caps in the morning, but was getting sick to my stomach and nauseas so I do one a day. Feel I can handle it better, not sure on weight loss yet, but I realty was interested in the liver information, I was diagnosed with a fatty liver and also when I was about 8 or 9 I had hepatitis.

    • Debi

      How’s it going? I too have a fatty liver.

      • Irma

        Leave a comment…Did or is this Active-PK working on your fatty liver? Did it reduce the fat on your liver?

  • Active PK ..A team effort
    Elio (Verified Purchase)

    I’ve been taking it for 3 weeks and i’m encouraged!
    Of course, i’m not doing pizza, nor tons of bread; and i have changed my eating habits…I thank my girlfriend for a Croc-pot she bought me a few years ago-I’m finally using it..
    Recently, i was able to endure 10 hours without a meal(too much at work) and cravings didnt do me in. I even faced a snack machine, and I left it alone…
    I really want to loose the weight I need to loose…I want a clean liver!!!!

  • Manuel

    Wonder how it goes with damaged liver

  • Try It!

    I’ve been taking Active PK for about 10 days and I’ve seen improvement. I’ve lost 5 lbs., and fat loss around my midsection, chin, arms and neck. I sleep better also. Not sure if that is due to the supplement, or if the loss in fat around my midsection makes my sleeping more comfortable.

    • Barbara

      I’ve been taking it for nearly 2 months with absolutely no results either in weight loss or visible fat reduction. What a disappointment. I’m afraid it’s just another s am.

    • Lisa in Texas

      This supplement will not do this. You ae probably cutting calories out of your diet.