Updated: 04/11/2017 - Site operated by Leptigen
By Summer Banks Mar 25, 2017

In the dietary supplement industry, don’t mistake marketing for effectiveness. We at DietSpotlight did one of our comprehensive reviews on Anatabloc, examining the side effects, ingredients, clinical studies and level of customer care. We also read numerous user comments from the internet. Lastly, we compacted and summarized to give you the info you need.

Anatabloc Readers: Click here to find out why we're giving away samples of our product, Leptigen.

What is Anatabloc?

First off, Anatabloc is an anti-inflammatory formula and it’s actually the brand name version of anatabine, which is an alkaloid compound that is found in tobacco plants. This product can be taken up to six times daily (a maximum of 12 tablets) and it may help reduce the symptoms of pain linked to arthritis, chronic inflammation, Alzheimer’s disease, Crohn’s disease and other body aches. Specifically, it claims to address and treat cellular inflammation. It is sold in stores such as GNC. It costs around $100 (300 tablets). The amount needed daily really just depends on your body weight.

From what we gathered, Anatabloc is manufactured by Star Scientific Inc. (Rock Creek Pharmaceuticals). It has been available since 2012. This formula is fine for both women and men alike and unlike most pills and capsules, it dissolves in the mouth, which some people will appreciate. Also, you can easily purchase this product online, but read on…

Mild Side Effects – “A Consideration?”

Our first concern we had with Anatabloc is the mild side effects that some people experience. “There are some complaints about mild adverse reactions, such as excessive burping, weak urine flow and nausea,” says our Research Editor.

“Since taking Anatobloc, I have been burping uncontrollably every time I eat or drink now,” commented one user.

“I’ve noticed the product causes my urination flow to become very weak and also a burning sensation while urinating,” said another person.

User Reviews of Anatabloc – “Some Negative”

There are some negative customer reviews posted on the web for Anatabloc. For instance, one individual stated, “The exorbitant cost alone will keep many from even trying this product.”

“I cannot sleep when I take this product!,” mentioned another user.

The intensive research we’ve done has shown that if there is a certain aspect of a dietary supplement or health product that is quite bothersome (mild side effects, negative user reviews, steep price) the probability of long-term success is slim. In other words, if Anatabloc does in fact lead to unhappy customers, this could be a serious dilemma.

Is There Any Real Science?

We were able to find some clinical research that supports the key ingredient used in Anatabloc, which is anatabine. Some studies have shown that this substance does help reduce inflammation. This is good to see, because we at DietSpotlight like to see some actual clinical studies that support the product we are reviewing. Unfortunately, there is no direct connection to weight-loss, unless you consider the pain relief in terms of performing exercise.

The Bottom Line – Does Anatabloc Work?

Now the moment you’ve been waiting for – our bottom line on Anatabloc. First of all, we appreciate that there’s research supporting the ingredient and it’s easy to purchase online. However, we have some reservations because some users have complained of negative side effects. There’s also the fact that it is not proven to have an effect on weight-loss.

If you are interested in shedding excess pounds of fat, then we encourage you to choose a product that is backed by solid clinical research, does not lead to any unpleasant adverse effects and sells at a reasonable price.

Among the best products we’ve seen this year is our product called Leptigen. This supplement contains four ingredients, all clinically-tested and seen in publications such as The Journal of Clinical Nutrition.

Also, we’re so confident that you’ll love our supplement, that we’re offering a Special Trial Offer, which is a great sign.

Previous Anatabloc Review (Updated July 19, 2012):

What You Should Know

Anatabloc is an anti-inflammatory supplement in lozenge form. The supplement contains just one active ingredient. We found some support for this ingredient in terms of smoking cessation and the company behind Anatabloc produces a smoking cessation supplement CiGRX with this same active ingredient. However, the clinical study needed to support using anatabine to reduce inflammation does not exist. Rock Creek Pharmaceuticals is working with the Roskamp Institute to study the effects of anatabine on inflammation. Currently, the only information on the Roskamp Institute website relating to this ingredient is associated with inflammation and Alzheimer's disease, not typical inflammation.

List of Ingredients


  • Vitamin A
  • Vitamin D3
  • Anatabine

Product Features

In November 2011, some forum posts popped up regarding a clinical trial of Anatabloc for chronic inflammation associated with some diseases, like Crohn's disease. According to one user's reaction, anatabine worked to reduce or eliminate much of the inflammation and pain associated with the condition. Not all doctors are sold on the effect, however. There is little clinical research on Anatabloc or anatabine. We found a few news stories about the current research results, but each quoted the same user over and over again. If the company wants to tout the positive clinical research, we need to hear from more than one user in the study.

There is no connection between the clinical research and basic inflammation associated with being overweight or obese. .The study concentrates on inflammation as a symptom of a disease process. Obesity is considered a condition of inflammation, but the symptoms are relieved by weight loss, not supplementation.

Anatabloc sells for $100 per 20 day supply. This is much more expensive than other weight loss and natural supplements for improved overall health. Without the clinical research to back up the supplement, we have little faith the company will sell many boxes until they can prove the supplement works for everyone suffering inflammation.


  • We found the list of ingredients on the official Anatabloc website.
  • There is a clinical study on the effects of Anatabloc on inflammation.
  • May relieve inflammation caused by the disease process.


  • Not all doctors are convinced Anatabloc works.
  • Not tested on overweight and obese dieters suffering inflammation separate from a disease process.
  • Only one testimonial is associated with the clinical trial.


Anatabloc could prove extremely beneficial for dieters who suffer inflammation, but there is just not enough data to support the supplement. Further research, or at least a more comprehensive explanation of the current studies results, is needed before this supplement can be supported.

Anatabloc Questions & Answers:

We narrowed down hundreds of user comments about Anatabloc into this helpful FAQ.

What are the side effects of Anatabloc?

The potential Anatabloc side effects, based on consumer reviews, include headache, muscle and joint pain, as well as upset stomach.

What are the ingredients in Anatabloc?

The Anatabloc ingredients are vitamin A, vitamin D3 and anatabine.

Does Anatabloc work?

There’s mention of one clinical study relating to the active ingredient in Anatabloc, anatabine. After further review, the findings were based on a questionnaire survey, not an actual clinical trial. The information also didn’t link the formula to weight-loss.

If you’re looking to lose weight, you may want to consider a supplement like Leptigen, which contains ingredients backed by published scientific research and proven to work.

How much does Anatabloc cost?

The cost of Anatabloc is $100, when it was still available for sale.

How should I take Anatabloc?

You should take one Anatabloc capsule per day.

Can I take Anatabloc if I have a health condition?

Those taking prescription medications, anyone with health conditions, people under 18 years of age or women who are pregnant or nursing should consult with a healthcare professional prior to using a dietary supplement of any kind, including Anatabloc.

What do users like about Anatabloc?

Some users liked the joint relief experienced with Anatabloc.

What do users NOT like about Anatabloc?

Based on customer comments, the majority didn’t like the high price tag of Anatabloc.

How do I contact the Anatabloc customer service department?

You can contact the Anatabloc customer service department by mailing letters to Rock Creek Pharmaceuticals 2040 Whitfield Ave. Suite 300 Sarasota, FL 34243, using the feedback form or by calling 1-804-527-1970.

Why was Anatabloc pulled from the market?

Anatabloc was pulled from the market because the company made claims not backed by research and didn’t contact the Food and Drug Administration for approval.

Do the makers of Anatabloc still sell supplements?

Yes, Anatabloc still sells supplements, but concentrates on research and development.

Does Anatabloc come with a guarantee?

There’s no guarantee with Anatabloc, considering the supplement is no longer for sale.

Do you know of any special deals or discounts on Anatabloc?

There are no deals or discounts on Anatabloc. The supplement is no longer available through the parent company or trusted retailers. However, our readers have been going wild over the last few months taking advantage of Leptigen’s Special Trial Offer, which is simply the cost of shipping and handling. Click here to give it a go.

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Dietspotlight Author
About the Author:

Summer Banks, a content strategist at Leptigen, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 3.9. From 96 votes.
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How Does Anatabloc Compare?

User Comments (60)


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My mom suggested this product because she saw it on tv. At the time, I had been suffering from several herniated discs down my spine. I truly believe this helped me to heal because therapy sure wasn’t working prior to taking it. I felt like my overal health was improved. I felt lighter, more youthful, healthy nails, hair & even had more muscle tone (a defined 6 pack with no exercise). I didn’t realize just how great this product worked when taking the appropriate dose, until after it went off market. The fact that it’s no longer available tells me it was monumental. We’ll never get a product like that again. It will be tweaked to not be as effective & sold at a ridiculous price. So sad when clearly, based on these comments, it helped so many who really needed the help. SMH!


best product ever for reducing and eliminating pain, period! Bring it back!!!!!

Neal shumate

This was the only thing that helped my joint pain my dr said there was nothing in it that would hurt me




I had a shoulder condition for about a year, seemed to be deep in the joint area of my left shoulder, it hurt all the time all the way down to my elbow, weakened the shoulder I would guess about 80% or more, could not sleep on that side at all, lifting with my left harm was painful, since most of these kind of conditions are inflamatory in nature I started looking for a natural anti- inflammatory to try rather than Advil or Tylenol, etc. I ran across Anatabloc in a extended search on line and decided to give it a try for a month, what did I have to lose, it was natural . Within 2 week the pain was half of what it was, within a month the pain was gone and the strength in the shoulder was back, have not had a problem since! So it was either one hell of a coincidence or it really worked, I choose the later!


Anatabloc keeps me able to use a knee previously too painful. I have been taking it for over 2 years & am now devastated to be told it is unavailable. I would have to stop all activity & would put on masses of weight. Is it possible to get any anywhere please?

christine filas

I have been taking Anatabloc for two years now. It has eliminated the joint pain caused by auto-immune hypothyroidism. I will never stop taking it.It has changed my quality of life.

ken ghronister

so far so good on it a month i’m a cohns patient since 1971 i have notice almost no joint pain. i’m avid pool player have been able to break a rack since last winter last night 7/13/14 broke aleast six racks slept the whole night through no pain more energy than i’ve had in years soon to be 66yrs old i would recomend to anyone.thanks ken

Alex Scott

I have suffered from inflamation pain for 30 years. I’ve tried everything to reduce inflammation and it’s side effects of pain. Nothing has worked for me, nothing. Until I tried this product. It works. Really works. I feel almost normal for the fist time in my adult life. I am 62 and very active physically. I finally have hope. I am going to buy this for my son who seems to have my symptoms I had in my early 20s. Going to get it for my
brother and sister who suffer from arthitis like myself. I’m sold!!!!

Pat kiland

I am delighted with the reduction of inflammation in my knees, shoulders, etc. been on this anatabloc for
One month and am very pleased with it. Hopefully, it will help others.


I heard about Antabloc from a stock trading buddy of mine. He said he had been taking it for pain and was buying stock in the company because it worked so well for him. So I ordered and tried for myself. I never seemed to be able to get into a regimen of taking the recommended dose, but took it more on the days when I was feeling more painful. It still worked for me and relieved the pain and stiffness in my hips, knees, neck and shoulders. I ordered the CigRx for my husband but it didn’t help him stop smoking. I didn’t experience any weight loss but I didn’t expect to since I wasn’t taking it regularly but just as needed. I don’t remember having any issues with sleep. I did have a bout of high blood pressure and dizziness once but I didn’t make the connection between the Antabloc and my one experience with those symptoms. I wonder if it is any better for your liver than the NSAIDS but I’m assuming it is. If I am taking the Antabloc then I don’t have to take the Advil or the Aleve.

ken chronister

p.s. forgot , almost 0 zero heart burn that saves me 20.00 couple $ a month.thanks again ken

Terez Kesmarki

I’ve been taking Anatabloc neerly 2 years. I don’t have any inflamation or pain anymore, but my blood preasure raised very high and I’ve lost 15kg. I’me very skinny right now and I have a very bad general state of health.

Tony Harris

since taking anatobloc I have been burping uncontrollably every time I eat or drink now … I think I am about to go to the doctor on this. I never have had indigestion before ever.


Taking the recommended dosage for my weight I’ve noticed the product causes my urination flow to become very weak and also a burning sensation while urination.

Michelle D

I was recommended to this product from my specialist and not sure if I am bowing out before it would kick in. I have the mint lozenges and have noticed a metallic taste in my mouth for the past few days. I am wondering if anyone else had this experience. Thanks for your feedback and happy to see so many who have benefited from this product!

Bruce Huff

Does this product elevate heart rate? I have A-Fib and must be aware of this.


My doctor recommended Anatabloc to me for overall achiness since i have a sensitive stomach with meds. After 6 days i woke with no pain in my feet upon standing up out of bed. My feet felt different, like they were on a thin cushion. I was expecting some kind of relief in my neck, which came a week or so later. Last year, I injured a hamstring which took months to get through. When bending to pick something up off the floor, I must do it slow and easy. After one month with Anatabloc, I can bend down with 70 % less restriction. I’m amazed. On the flip side, I seem to have developed bright red, somewhat irritating bumps on my neck, back, hip and upper thigh. ( 6 in all- – over 1 month’s time ) Is this common ?


how does anatabloc work with blood thinners.

vittorio romeo

Anatabloc helps my joints pain.But I have a metallic artificial mytrovalve and I need to take the perfect amount of blood thinners daily.Does Anatabloc interfere with blood thinners?Does Anatabloc effect blood thickness?

ellen brown

does anatabloc cause any itching or bumps on hands and feet?