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BiphedAdrene Review - 23 Things You Need to Know

Claiming to promote weight loss through appetite suppression, BiphedAdrene isn’t your grandmother’s diet product. But with ingredients like Mate Leaf Extract that are not clinically proven to help with weight loss, we were immediately skeptical.

Our team of researchers was too. They looked deep into the full ingredient list, any possible side effects, and available scientific research while we looked into hundreds of customer testimonials. We’ve refined and condensed that information here for you today, to give you the Bottom Line on BiphenAdrene.

BiphedAdrene Readers: Noom is offering our readers a free trial, for a limited time. Click here for this special offer!

What is BiphedAdrene?

BiphedAdrene is a brand of diet pills aiming to promote weight loss. Generix Laboratories, the manufacturer, claims that it works by suppressing appetite, boosting energy levels and stamina, and improving the overall mood. It comes in two capsules, a purple and yellow one, which users need to take together.

BiphedAdrene promotes fat-burning through thermogenic processes, thus accelerating the body’s natural fat-burning. Its reviews suggest that you should only use BiphedAdrene for significant weight loss. Those who are looking to lose five to six pounds should not take this product.

Generix Laboratories claim that BiphedAdrene is a two-part system: an aggressive thermogenic compound to boost stamina and burn fat, and a “complex phenylethylamine provisional” to improve customers’ mood and energy while decreasing their appetite.

Products Similar to BiphedAdrene


How Did BiphedAdrene Start?

Generix Laboratories Ip Holdings LLC registered BiphedAdrene in October 2012, according to the United States Patent & Trademark Office. BiphedAdrene’s active ingredient is a central nervous system stimulant, a class that includes mainly veterinary and medical preparations and pharmaceuticals.

BiphedAdrene appears to be Generix Laboratories’ primary product. We know little about the production of BiphedAdrene except that the company makes it in Salt Lake City, and that they introduced it to the market in 2012.

Over the past decade, there has been a surge in the number of products that promise cheaper, quicker, and less painful weight loss. According to Bio-Medicine, in 2008, Americans spent about $55 billion on weight-loss products and services.

This means that competition is quite fierce and that customers will always favor any product that makes stronger claims than the alternatives. This explains the popularity of BiphedAdrene, as Americans search for an easy way to lose weight, while still enjoying their favorite meals.

BiphedAdrene Customer Testimonials

BiphedAdrene Ingredients

BiophedAdrene #1 (purple)

  • Trimethylxanthine
  • Paulinia
  • Arbutin
  • Phenylethylamine
  • Theobromine
  • Microcrystalline
  • Cellulose
  • Croscarmellose sodium
  • Stearic acid
  • Magnesium stearate
  • Polyvinyl
  • Polyethylene
  • Aluminum lake talc
  • Titanium dioxide
  • Caffeine

BiophedAdrene #2 (yellow)

  • Ilex paraguariensis extract
  • Guarana
  • Methylxanthine
  • Turnera
  • Capsaicin
  • Serotonin
  • L-dopa
  • Gelatin
  • Rice flour
  • Stearic acid
  • Magnesium stearate
  • Titanium dioxide
  • Silicon dioxide
  • FD&C Yellow

BiphedAdrene Claims

Generix Laboratories claims that BiphedAdrene can help suppress the appetite, which in turn promotes weight loss. A mood-enhancing effect and energy boosting properties support this. Although BiphedAdrene contains ingredients that have health benefits, there is no scientific research into the company’s specific claims.

biphedadrene claim

Mate Leaf Extract

BiphedAdrene’s main ingredient is mate leaf extract, which allegedly helps with weight loss. According to the journal Nutrients, people also use it as a stimulant to fight mental and physical fatigue, as well as to promote heart health. Some also use a mate to treat urinary tract infections (UTIs).

Notwithstanding mate’s health benefits, we do not currently understand how it might affect the complex processes that lead to weight loss.

Damiana Leaf Extract

The Mayans of Mexico used this ingredient as an aphrodisiac. People have also used it as a treatment for headaches, and constipation, and research has shown that damiana can promote weight loss.

You should note that, thankfully, the Food & Drug Administration (FDA) has approved damiana for human consumption and has given it a reasonable GRAS rating.

Cayenne Pepper

Cayenne pepper is another key ingredient in BiphedAdrene. According to studies by the journal Bioscience Reports, the oral administration of cayenne pepper leads to a short burst of heat, which boosts the metabolism and burns more calories.

Information on the exact amount of these ingredients in BiphedAdrene, though, is lacking. This makes it hard to link the studies supporting the efficacy of these ingredients to BiphedAdrene. This is because these ingredients may not be present in sufficient amounts for BiphedAdrene to act as an effective weight loss supplement. Likewise, there need to be some scientific studies to examine the before and after effects of BiphedAdrene.

biphedadrene ingredients

Does BiphedAdrene Work?

We found no scientific studies testing BiphedAdrene to determine its efficacy. Although there is research demonstrating the usefulness of individual components, there has yet to be any study that examines them in combination.

According to Nutrients, mate contains caffeine and other active ingredients that can stimulate the brain and other organs. This could improve metabolism, promoting weight loss.

A study by the McCormick Spice Company and National Institute of Health showed that cayenne pepper could help curb the appetite and burn calories. This is especially true for those who are not used to eating it, and thus may have a lower tolerance. According to the study, when they swallowed half a teaspoon of cayenne pepper in capsule form or with food, adults with normal weight burned extra calories over four hours.

We need further studies to examine if BiphedAdrene has a similarly short life.

Benefits and Results

BiphedAdrene Benefits and Results

According to the Cleveland Clinic, diet pills can help you shed some pounds, but the results won’t last long. This is further complicated for BiphedAdrene reviews, as it is unclear if the positive results are just due to BiphedAdrene or the result of lifestyle and diet changes. However, there is some research that shows how some of the ingredients work. Damiana can effectively enhance users’ sex life, and there are claims that mate is an effective treatment for some conditions. Overall, we require further research.

Regardless, the benefits of using BiphedAdrene, before and after meals, allegedly are:

  • Controlling hunger by suppressing the appetite
  • Mood enhancement
  • A unique combination, making it an exceptional diet pill
  • Thermogenic compounds that quickly burn fat

biphedadrene weight loss

BiphedAdrene and Weight Loss

To date, there are no scientific studies on how BiphedAdrene affects weight loss. However, some studies have shown that its ingredients do have weight loss-promoting properties. For example, damiana can improve physical stamina and mate contains caffeine, which acts as a stimulant. The only ingredient, though, shown to have a direct link with weight loss is cayenne pepper. These links, while useful, do not help evaluate the positive customer reviews of BiphedAdrene, as there is no breakdown of the quantities of the ingredients in BiphedAdrene, which means that you cannot judge the specific impact of the supplement.


How to Take BiphedAdrene

The instructions on how to take BiphedAdrene depends on why you are taking it. Adults using the product to promote weight loss should take one yellow and one purple tablet with a full glass of water fifteen minutes before meals. For those who want to use BiphedAdrene to boost their energy levels, one yellow and one purple tablet should only be taken as required. Customers are also warned to not exceed three servings of each tablet within a twenty-four-hour period. Generix Laboratories also recommends that BiphedAdrene use is combined with a sensible diet and healthy exercise program.

Side Effects

BiphedAdrene Side Effects

One possible adverse effect of using a product that contains caffeine is the possibility of addiction. The lack of data on the long-term effects of prolonged use of the product also makes it hard to judge if BiphedAdrene works. It is common knowledge that, in the pharmaceutical world, any product with positive results can be rejected if its long-term effects are sufficiently negative.

Mate is also known to be very high in caffeine, which is problematic, as it is unknown how much mate is in BiphedAdrene. Guarana has also been linked to dizziness and nausea. The damiana in BiphedAdrene may also affect sugar levels in the bloodstream.

Even though cayenne pepper has been known to promote weight loss, due to its thermogenic properties, it is unknown how strong the effect is. The fact that there may only be a small amount of it in BiphedAdrene also means that it may not offer the fast-acting effects as claimed by the manufacturers. As with all supplements, you should consult your doctor before using BiphedAdrene, especially if you are taking any other pills or if you suffer from any ailments.

Product Warnings

BiphedAdrene Product Warnings

BiphedAdrene comes with a series of warnings from the manufacturer, written on the packaging. The first, and strictest warning is not to exceed the suggested daily serving size. Users are also advised not to consume more than one yellow and one purple tablet within four hours. Individuals under eighteen years of age and pregnant or nursing women should also not take BiphedAdrene. As it contains a significant amount of caffeine in each 300-mg serving, it should also be avoided by those who are allergic to caffeine or who use other stimulants.

Generix Laboratories advises potential consumers to consult their physician before taking BiphedAdrene if they are sensitive to stimulants or have a history of:

  • Seizures
  • Recurrent headaches

They also advise that you should immediately consult a physician if, while taking BiphedAdrene, you experience a severe headache, rapid heartbeat, shortness of breath, or similar symptoms. Generix Laboratories stresses that it is important not to exceed the daily dosage or take BiphedAdrene more frequently than instructed, as this may result in adverse side effects.

It is also claimed that those sensitive to niacin, or nicotinic acid, may experience flushing of the skin.


Any BiphedAdrene Lawsuits?

We checked online but did not find any lawsuits pending against BiphedAdrene or Generix Laboratories. Historically, the FDA has been quite strict on supplements and their manufacturers if they have been viewed as potentially unsafe. The fact that there have been no lawsuits, or FDA action against BiphedAdrene to date, is a good sign.

BiphedAdrene Alternatives

The truth of these diet pills is that they often lighten the customer’s wallets more than their body. Manufacturers’ assertions are often unverified, and they sometimes do not work as claimed. Despite the wide variety of supplements available in the marketplace, many of them do not contain the same ingredients as BiphedAdrene. This means it is not possible to directly replace BiphedAdrene, but some of the best alternatives are:

Where to Buy

Where Can I Buy BiphedAdrene?

BiphedAdrene can be purchased on the websites of other major third-party retailers, such as GNC and Walmart. Those who prefer to buy their supplements in stores can find BiphedAdrene in GNC stores.

biphedadrene buy

BiphedAdrene Money Back Guarantee

According to Walmart, GNC, and Amazon, whenever you buy BiphedAdrene, you get a 30-day money back guarantee so that, if you are not 100% satisfied with the product, you can get a refund. However, some customers complained that the details of the money-back guarantee were confusing, as there is no explanation of exactly where the customer should return it to get their money back. Also, customers point out that there is no information available on this 30-day, money-back guarantee on the official website. To this end, the third-party retailers have posted more information about the details on their websites.

Is BiphedAdrene FDA Approved?

The FDA has been known to pull drugs, such as Fen-Phen and Ephedra, from the market due to safety concerns. To date, there has been no attempt to remove BiphedAdrene from the market. The only FDA statement about BiphedAdrene is to warn that the claims made about the product have not been scientifically evaluated.


BiphedAdrene Price

The price of BiphedAdrene depends on where it is being sold. Here are the common prices are given for BiphedAdrene:

  • BiphedAdrene.com: $135
  • Amazon: $71.25
  • GNC: $59.99

How Many Tablets Are Contained in a Pack of BiphedAdrene?

Each packet of BiphedAdrene contains 120 tablets, covering the recommended dosage for a thirty-day course. This is broken down into:

  • 60 tablets of the complex phenylethylamine provisional
  • 60 capsules of the aggressive thermogenic compound

BiphedAdrene Discounts

Biphedadrene.com offers huge discounts to consumers, with the savings increase with the amount purchased. When you buy two packs of BiphedAdrene from the website, you get one free, meaning you save $135. This means you save more through the website, although the third-party retailers have some deals. When buying through GNC, you get free shipping; meanwhile, you get 5% off through Amazon.com.

When to Take BiphedAdrene

According to the manufacturers, BiphedAdrene is best taken with a full glass of water, before meals. Users should take one capsule each of the aggressive thermogenic compound and the complex phenylethylamine provisional.

What Makes BiphedAdrene Unique?

The manufacturers claim that BiphedAdrene is unique, as it contains a unique combination of ingredients. It is hard to substantiate this claim as the exact quantities of the ingredients are not specified. However, other weight loss pills contain similar ingredients, perhaps even in similar ratios.

When Will BiphedAdrene Begin to Work?

Most positive reviews claim that BiphedAdrene worked quite quickly, but there is no real understanding of the timeline. The lack of scientific backing for these claims also makes it hard to judge how long BiphedAdrene takes to work.

What Users Are Saying

What Users Are Saying

“I have been taking this for a couple years and love it….. I don’t use it for weight loss…I use it for the energy boost and the mood elevator…I take 1 tablet and break it in half….take 1/2 when I get to work and the other 1/2 after lunch….I have low blood pressure and it gives me the boost I need to get through the day and keeps me in a pretty good place mentally, and being in customer service it can get trying…Please bring it back….”

“I took these for quite awhile and did not notice a difference in my weight.”

“It works for me as I work long hours.”

BiphedAdrene Ingredients
Bottom Line

The Bottom Line on BiphedAdrene

Well now, what can we say about BiphedAdrene? We like the favorable BBB rating and the money-back guarantee, but we have doubts about recommending it because of the lack of scientific research supporting the weight-loss claims. Plus, customer reviews are talking about negative side effects and limited results.

If you’d like to lose the fat, we recommend going with a product delivering great results and clinical support.

Among the best products we’ve seen this year is one called Noom. The idea behind the doctor-created app is to combine what works into one app so you don’t have to search everywhere for the support you need. This includes human coaching and a completely personalized weight-loss plan.

Also, the company behind Noom is so confident in the program; they’re offering a free trial, which is a good choice.

Learn More About Noom »
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What are the side effects of BiphedAdrene?

Biphed’s (short for BiphedAdrene) potential side effects may include jitteriness, nervousness, sleeplessness, muscle spasms, irritability, anxiety, upset stomach, nausea, increased heart palpitations and vomiting, according to some people who’ve tried it. 

What is in Biphed?

BiphedAdrene ingredients are trimethylxanthine, caffeine, α-phenylethylamine, β-phenylethylamine, phenethylamine, theobromine, microcrysalline cellulose, stearic acid, magnesium stearate, silicon dioxide, croscarmellose sodium, polyvinyl alcohol, polyethylene glycol, erythrosine aluminum lake, talc, titanium dioxide, fd&c blue #1 aluminum lake, fd&c #2 carmine aluminum lake, ilex paraguariensis, guarana, methylxanthine, tumera, capsaicin, seratonin, l-dopa, gelatin, rice flour, titanium dioxide, fd&c yellow #5 and fd&c yellow #6.

What is the active ingredient in BiphedAdrene?

The active ingredient in Biphed is caffeine.

Does BiphedAdrene work?

There’s no science to back the claims that BiphedAdrene is a more effective weight-loss supplement than others that are stimulant-based. There are studies into caffeine,  but that is found everywhere and doesn’t relate to this formula.

How much does a bottle of BiphedAdrene cost?

A bottle of BiphedAdrene costs $135 for a 60-day supply.

How do you take BiphedAdrene?

You should take one purple and one yellow BiphedAdrene capsule prior to your main meal. Each box contains a 60-day supply. The company recommends not exceeding four capsules in a 24-hour period.

Can I still drink coffee on BiphedAdrene?

No, you can’t drink coffee on BiphedAdrene. The company recommends not consuming additional caffeine while taking this supplement.

How much caffeine does BiphedAdrene contain?

Each serving of BiphedAdrene contains 260mg of caffeine.

Does Biphed come with a guarantee?

Yes, BiphedAdrene comes with a guarantee. You have 30 days to return the supplement for a full refund.

When searching for weight-loss supplements that are truly effective and not gimmicks, search for clinically tested ingredients from a company that offers amazing results. Dietspotlight Burn is one we’ve speculated and works efficiently.

19 BiphedAdrene Reviews

  • I'm going back to gnc to return this, it's not worth my health.
    Bri (Verified Purchase)

    This is my third day taking the pills and I’m seriously considering calling it quits. You feel the energy boosts after 15 minutes which is great. However, sleep has been difficult and now my symptoms include my limbs tingling (like when circulation suddenly rushes through) and my fingers started moving involuntarily for 5 minutes. I’m 22 years old 5′ 7″ and 200lb. I’m going back to gnc to return this, it’s not worth my health

    • Montana (Editor)

      Hi Bri. We’re sorry you suffered from such bad side effects! You may want to think about switching to a weight loss supplement that comes with little side effects, like Dietspotlight Burn.

  • Body is reacting differently
    anika (Verified Purchase)

    My heart starts palpitating, i start getting shortness of breath! i cut my intake down to one serving per a day. i’m so freaked out.

  • It will show good results after two weeks.
    Ali (Verified Purchase)

    I was introduced to biphedadrene by my roommate she gave me 40 pills (20 purple and 20 yellow) I lost 30 lbs in a month. I look so good. It’s not just taking the pills that will get you results you need to diet and exercise. I was hitting the gym 6 days a week for about 3-4 hours at a time. I was also running every morning. My diet was poor not because I was eating bad food but because I wasn’t eating enough to give my body the protein it needed for my muscles with all that work I was doing. Negative side of effect for sure is my insomnia. I can seem to be able to sleep for a couple nights and then one day I’m so exhausted I just crash sleeping for hours in the middle of the day. But I go to the gym late around 10pm and leave at 2 or 3 am. I stopped taking them for a couple months but just bought a new box a couple days ago. I just take the pills right before I work out once a day that’s it so they last me a good amount of time. I’m a college student living on my own paying my own bills with a 2 jobs and I can afford them. They’re worth it!!! But give it 2 weeks to start seeing results and a month for others to see it. Exercise and diet or else you won’t progress as dramatically

    • Your Name

      Lost 30 lbs in a month. Ok!

    • Your Name

      Pretty sure it was hitting the gym and running 6 days a week that made u lose weight not the stupid pills.

  • I love it !
    Ben (Verified Purchase)

    I love it its like adderall to me I have tons of clean energy energy from it .. It also reminds me of the old redlines vpx drinks

  • 2 weeks no results !
    Tammy (Verified Purchase)

    Paid over 100. For this cause of advertisements been talking it for over 2 weeks haven’t lost a pound and I walk allot I also have hypothyroidism tale medicine for that haven’t had any side effects at all days money back guarantee on box hope it’s true still have receipt from gnc so now what

  • Facing side effects.
    kathy (Verified Purchase)

    i just started taking biphedarene 2 days ago.i need to lose 80 pounds. i’m going to be pissed if this doesn’t work. i paid 100.00 at gnc for this. i pray it works without giving me headaches.

  • Never felt better
    Sarina (Verified Purchase)

    So far I would like to say that these pills work. I mean as long as you’re taking as directed you shouldnt have a problem. I started taking these two days ago and I’m already seeing a difference in my appetite, weight, and even my mood. I am not wanting to eat as much and I have lost like 3 pounds already. I went from 203 lbs. to 200 lbs. and it makes you energized and wanting to do something all day. Honestly I’ve never felt better about myself than I do now. I’m hoping I don’t have any reactions to the Biphederene but you never know because it really doesn’t help that they won’t give out all the ingredients in this product. I wish the best for anyone who is taking it. I am 18 going on 19 and I take the pills once daily and eat portion sized meals 3 times a day and I also try to exercise more than an hour a day. It seems to be helping me so I would probably recommend it.

  • domino 88 asia

    whoah this blog is great i like studying your articles. Keep up the great paintings! You recognize, lots of individuals are hunting around for this information, you can aid them greatly.

  • Can someone provide more feedback?
    Deana Payne

    Hello im Deana Payne i would love to here from some one thats tryed this becouse im a 47 year old femaleand im 5ft/4in tall and kind of top heavy but between us i weight 178lb thats a lot im taking thynoid meds and more then a few outhers dut i still need some thing to help me get fid of about 35-40lbs around ther

    • Brandy Bueno

      Deana, I am 40 yes old & we are the same height & weight. I just keep getting bigger! I have no energy therefore I don’t exercise. My question for you is have you tried the Biphedadrene yet? I don’t want to waste more money on more lies. Please let me know what you think


    • Anonymous

      Not a good idea on thyroid meds. U have to be really careful with strong diet pills and thyroid. My opinion, not worth the risk for you. Try to find something more natural.

  • How to use it?
    virginia weaver (Verified Purchase)

    I got my box of biphedadren on may 24th 2013 and have been taking it like it said but I would like to know how long it will be before I start to see weight loss.. I did not get any book telling me what to expect from taking these diet pill’s.

    • jaytee404

      I took this for I think two months with moderate exercise and diet. I didn’t take it seriously but by the end of two months I had lost alot of weight. I started to notice my jeans very loose they weren’t holding onto my body anymore, everybody was in shock and when I got on the scale, I was weighing 124lbs from my usual 143lbs. Love it

  • Loved the product.
    Evy Vaudrin (Verified Purchase)

    This is my first day trying BiphedAdrene. Wth all the bad reviews I’ve seen from a few websites, it almost completely discouraged me from getting this product, but i have to say that i’m loving it so far, after taking the first dose yesterday morning it started to work in 15 mins! i felt the rush of energy that made me want to get out of my pj’s and exercise, instead of lounge around sitting in front of the tv watching re-runs of gossip girl. I’m 5’6 and 100lbs over weight and i’ve been wanting to lose it but had no energy and always felt down, but i feel great! which contributes to me want to be more active and is definately a plus. My appetite has decreased and im not constantly thinking about food, i did noticed that i’ve been super thirsty and have been drinking more water which i normally don’t do, so that’s another plus. i started this with my sis-in-law and she feels the same, that this is working! the only downfall about it is that its very costly, but i’m glad i can purchase it through Amazon and i can take advantage of the prime thing and get the shipping for free and that they are super quick too! so heres’s my 1 vs 1000 great review!! so i’d say give it a try and if doesn’t work for you.. then move on!

    • lorraine

      drink more water

  • Loved the product.
    Alyssa (Verified Purchase)

    I’ve been on it 3 days. No negative side effects. Lost 4 lbs in that amount of time and I’m a lot more energized and seemed to put me in a more positive mood. I take it twice a day and I have zero problem sleeping. I would recommend it so far.