I just read, “In a world full of unhealthy options, Calotren stands alone.”
While this sounds great, I still want to know:
What sets this supplement apart from the competition?
Let’s find out: Calotren claims to have safe and natural ingredients, where others simply do not. They claim that they have “side benefits” where others only have side effects. They say that they employ a full staff of medical professionals, and to top it all off, they have been around for over 20 years.
So what’s the problem? The answer might surprise you.
Read these 5 facts you NEED to know about Calotren.
Let’s jump right in…
What is Calotren?
Firstly, Calotren is a weight-loss supplement. The ingredients are:
- Collagen Hydrolate
Take four capsules at bedtime with eight ounces of water and supposedly helps your body burn off sugars and fat. One benefit is that healthy eating is encouraged. 
Top of the World Distributors released Calotren in 2010. The company was founded in 1997. You can buy the product through trusted retailers. This supplement doesn’t contain any stimulants and no special diet is required, but read on…
No Real Clinical Evidence – “A Problem?”
Our first concern with Calotren ingredients is a lack of clinical support.“There is no actual evidence presented on the formula regarding weight-loss or fat reduction,” said our Research Editor. “While this supplement may help with protein absorption, this could be why some customers didn’t see results.” 
One user said, “I tried Calotren for a month and received no results. Worked out, cut back food in-take and didn’t eat after 7pm every night. Didn’t feel any different health wise either.”
Another stated, “Well it don’t work for my wife, and she’s not very happy about this product. I think she gained weight instead of losing.”
Negative Customer Reviews – “Not Good”
While we were able to find a few customer testimonials posted online for Calotren, there are also negative user reviews. One dieter said, “If you are at all sensitive to taking pills, don’t do this! I followed the instructions, waited the 3 hours after eating before taking it, and then barely slept all night. It says “no stimulants” but something kept me awake and feeling sick all night.” 
“I tried Calotren for three months. Did not loose any weight. It was a waste of my money. Would not recommend it to anyone,” claims a buyer
Our research has proven if a specific part of a weight-loss product or diet formula is especially problematic (a painful/difficult exercise routine, no clinical research, too many customer complaints) the likelihood of real success, for the long run, is slim. If Calotren does in fact fail to produce results and leads to bad reactions, as reported by some customers, this could be a major issue.
The Science of Calotren – “Nothing Available?”
There is no scientific research presented for Calotren. For us at DietSpotlight, we need to see documented clinical support for the supplement and its ingredients. While this product is claimed to produce great results, there is simply no real evidence to support fat loss or weight management. Also: read our Burn HD Weight-Loss Kit review »
The Bottom Line – Does Calotren Work?
Let’s take a closer look at our results, shall we? Calotren is an interesting weight management supplement and it does contain some intriguing ingredients. However, we can’t recommend this diet product because there is no published clinical data to support this formula. Furthermore, Calotren is quite pricey at $69.95 per bottle. Not to mention, there are no customer testimonials about the product. 
For dieters who need to slim down and shed pounds more quickly, we suggest you to go with a weight-loss supplement that is both affordable and backed by real scientific studies and supportive customer reviews.
Among the best products we’ve seen this year is our product called Dietspotlight Burn. This proprietary blend of four ingredients is clinically-tested with results often found in studies published in The American Journal of Clinical Nutrition.
Plus, we’re so confident that you’ll love our supplement, that we’re offering a Special Trial Offer, which is a good sign.
Previous Calotren Review (Updated February 6, 2014):
What You Should Know about CalotrenThe weight loss product Calotren is a protein supplement manufactured and distributed by Top of the World Distributors. Calotren seems to claim to be a metabolic supplement that is suitable for both overweight users and users looking to improve their metabolic health. Interestingly, Calotren seems to come in both liquid and capsule form. A 30-day supply of the supplement retails from the manufacturer for approximately $65.00, making it a moderately expensive regimen to maintain. Instructions for Calotren use indicate that a full course of the supplement is intended to last 90 days, yielding weight loss and a more toned physique. If this is out of your budget, you might want to consider Addrena as it's a dietary supplement used to boost energy levels and enhance metal focus while encouraging fat loss. Both the liquid and capsule forms of Calotren are protein-based formulations. The product contains no ephedra or caffeine, both of which have been found to over-stimulate the metabolism and potentially cause rapid heart-rate and "jitters." The official product website goes out of its way to point out that Calotren does not "stimulate, starve or trick" your body. While that does sound appealing, the further product claims are a bit ambiguous, implying that Calotren acts as a "support" for the body's natural fat burning cycle, while also boosting stamina in non-overweight users. This ambiguity, both as to the product's applications and its active ingredients, strikes us as a bit off. The mysterious Calotren protein also claims to benefit wrinkled skin.
List of Calotren IngredientsThe active ingredients of liquid Calotren are: Oxygenated water, Collagen Hydrolysate (Bovine Source), Aloe Vera, Glycerin, Potassium Sorbate, Natural Raspberry Flavoring, Methyl Paraben. The active ingredients in capsule Calotren are: Collagen Hydrolysate (Bovine or Marine Source - your choice), Aloe Vera, Vegetable Glycerin. Inactive ingredients in both forms of the product: Gelatin, Magnesium Stearate, Stearic Acid and Microcrystalline Cellulose.
Product FeaturesCalotren is intended to be taken once per day. Take either a single tablespoon or four pills of Calotren in the evening before going to sleep. For most effective results, do not eat anything three hours prior to taking the product and, if taking the pills, use only a glass of water to wash them down. This is so that your body can begin using the Calotren while you sleep. Top of the World Distributors also claim that taking Calotren in the morning or before exercising will give users increased energy. Calotren is laced with Aloe Vera, which has been known to transform fat and carbohydrates into energy, rather than storing them in the body.
Advantages of Calotren
- Product is available from manufacturer online.
- Product does not contain caffeine or ephedrine.
Disadvantages of Calotren
- Product claims are very broad, making it sound like an all-around "miracle" supplement. We'd prefer a product that focuses specifically on weight loss.
- Reading the ingredient list, we see no proprietary ingredients that separate this product from others.
- No free sample.
ConclusionWhile we certainly appreciate that Calotren does not contain caffeine or other potentially harmful stimulants, like Animal Pak, but we're not really impressed by what it does contain. We are also weary of any product that claims to help with weight loss, boost energy and clear up wrinkles, all in one package. With so many proprietary products on the market for the same price, we'd hold out for something that can offer more sophisticated lab research and an approach that is specifically targeted towards weight loss.
Calotren is a weight-loss supplement from Top of the World Distributors. According to the company, customers have reported decreased joint pain, improved sleep and increased energy. There is a liquid and a capsule with the program. The ingredient lists don't show anything with strong clinical support, in terms of weight-loss.
Calotren Ingredients and Supplement Facts
Serving Per Container: 30
|Amount per Serving||% DV|
|Calotren Advanced Capsules||*||*|
|- Collagen Hydrolysate||*||*|
|- Aloe Vera Leaf Extract||*||*|
|- Collagen Hydrolysate||*||*|
|- Aloe Vera||*||*|
Other Ingredients: May include: filtered water, gelatin, vegetable magensium stearate, vegetable glycerin, natural and artificial raspberry flavor, potassium sorbate, citric acid, sodium benzoate
We examined the Calotren ingredients in order to give you the facts you need.
Collagen hydrolysate is an amino acid, in which high amounts of glycine, lysine, and proline, which are not often found in other protein supplements. 
What Is It Supposed To Do?
Collagen hydrolysate is often used as an extra nutritional aspect in dietary supplements.
According to a study published in Current Medical Research and Opinion, “e results of this study have implications for the use of collagen hydrolysate to support joint health and possibly reduce the risk of joint deterioration in a high-risk group. Despite the study’s size and limitations, the results suggest that athletes consuming collagen hydrolysate can reduce parameters (such as pain) that have a negative impact on athletic performance.” However, nothing was said connecting it to weight-loss.
Aloe vera is a plant composed primarily of water. However, it contains many minerals that can be beneficial to the body.
What Is It Supposed To Do?
Aloe vera has many benefits to the body, including aiding in digestion, fighting disease, and helping the immune system.
In an article published in Herbal Medicine: Biomolecular and Clinical Aspects: 2nd Edition, “Despite its long history of use, there remains a lack of consistent scientific evidence to support many of the therapeutic claims for Aloe vera.”
Filtered water is just regular water that has been pushed through a filter, where it becomes cleaner.
What Is It Supposed To Do?
Though water is generally essential for any life, filtered water can prove to have some benefits, including activated carbon, aeration, cation exchange, distillation, reverse osmosis, and UV disinfection.
In a study published in Nutrition Reviews, “Both studies reported more rapid weight loss among pre-meal water drinkers.” This does not count for supplement because this study was conducted with the consumption of water before meals.
Vegetable glycerin is a clear liquid that has a sweet taste. It is used commercially for cosmetics and food.
What Is It Supposed To Do?
Vegetable glycerin is used for solvents, sweeteners, antifreeze, soaps, cosmetics, and more.
In a study published in Metabolism: Clinical and Experimental, researchers noted, “Glycerol [another name for vegetable glycerin] did not differ from an equicaloric dose of glucose in its effect on hunger ratings, diet compliance or overall weight loss. We conclude that oral glycerol is not a useful adjunct to weight reduction programs.” 
Scientific research is critical to the review process, so one that’s caught our attention is one called Dietspotlight Burn. It contains clinically-tested ingredients and has been shown to work. Click above to learn more.
- 1. Amino Acids to Produce Collagen (2015). LiveStrong. March 19, 2013.
- 2. Effect of glycerol on weight loss and hunger in obese patients. (1980). National Center for Biotechnology Information. September 4, 2012.
Calotren Scientific Abstracts:
Following a 24-week-long trial of athletes that were given a collagen hydrolysate supplement findings conclude that collagen hydrolysate could be used to encourage joint health and probably decrease the chance of weakening joints in a high-risk group. Results recommend that athletes that ingest collagen hydrolysate could reduce negative limitations on performance. 
While not scientifically proven, it has been suggested that collagen weight loss products can enhance lean muscle mass and encourage fat burning. It was noted that a hydrolyzed collagen product would demonstrate effective weight reduction in 50 overweight people. The same study that was conducted by Essentially Yours Industries Corp. Office of Product research concluded that when consumed daily in one tablespoon increments a collagen hydrolysate product generated weight loss of an average of 10 pounds in a three-month span. 
When used as a component in protein supplements or meal substitutes, ProHydrolase that was created to construct muscle mass and speed up muscle healing. Through clinical studies, it has been found to process protein in a bio-useable structure while gaining the accessibility of vital amino acids for building muscle and better muscle recovery. It was found to be successful with whey, casein, soy, egg, and pea and hemp proteins. It has been shown through two different studies ProHydrolase’s ability to boost amino acids in the blood by 20 percent, aiding in muscle mass building and enhancing the recovery of muscles when it is paired with a protein supplement.
Aloe Vera Leaf Extract
Aloe vera, a common healing plant that is well known for taking care of skin wounds, has been around and used for thousands of years. Aside from being good for the skin, there are many other health benefits of aloe vera. It possesses antioxidant and antibacterial properties. It’s most common use is as a topical medicine for lesions and burns. Studies show that also vera may assist in decreasing the time it takes a wound to heal by nine days compared to other medications. Studies found that using aloe vera as a mouth rinse was as successful as the common ingredient in mouthwash chlorhexidine at eliminating plaque bacteria and yeast in the mouth. Aloe vera has been strongly studied and proven to speed up the curing of mouth ulcers. Another study showed that while aloe vera sped up mouth ulcer recovery, it also decreased the pain that comes with them.
Aloe vera has been said to help with constipation when using the latex form; the main compound aloin is what contains the laxative impact. Since 2002, aloe vera latex has not been accessible as an over the counter drug due to safety alarms linked to consistent use. It has not been found that aloe vera is successful against digestive illnesses like irritable bowel syndrome (IBS) or inflammatory bowel syndrome (IBD). Some initial findings show that aloe vera gel can slow down the skin’s aging process. It was found through a 90-day study that aloe vera gel applied to the skin increases collagen construction and enhanced the elasticity of the skin. Aloe has been said to lower the blood sugar levels in people with diabetes. Hopeful results were found from ingesting aloe vera extract through many studies of type 2 diabetics, although the quality of these studies is weak. 
- 1. 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activity-related joint pain. (2008). Current Medical Research and Opinion. October 13, 2016.
- 2. Hydrolyzed Collagen for Weight Loss (2013). Livestrong. November 2, 2016.
- 3. Systematic Review of Herbs and Dietary Supplements for Glycemic Control in Diabetes (2003). American Diabetes Association: Diabetes Care. October 7, 2016.