Updated: 09/12/2017
By Summer Banks Sep 04, 2017

This review is what happened after I obsessed for weeks over Contrave. We decided to take an in-depth look at the prescription diet pill, side effects, ease of acquiring and clinical research. Additionally, we examined hundreds of dieter comments and testimonials. Then, we summarized and refined to give you the info you need.

Contrave Readers: Click here to find out why we're giving away samples of our product, Burn HD.

What is Contrave?

To start, Contrave is a prescription weight-loss medication for individuals who have a BMI [1] of 30 or greater or a BMI of 27 or greater with medical condition related to their weight [2]. The ingredients are bupropion hydrochloride and naltrexone hydrochloride. You’ll take one tablet each morning for the first week. The second week you’ll use one in the morning and another in the evening. By the third week, it’s two tablets, twice per day. Dosage depends on the prescription received from your physician. [3]

Contrave [4], approved by the FDA and hit the market in 2014. Orexigen Therapeutics makes the medicine; which affects the appetite and reward center of the brain. We like that we found some positive dieter comments and that a healthy lifestyle is encouraged, but read on…

Contrave High Cost – “Too Expensive?”

The first concern relating to Contrave ingredients is the high price tag. “The cost of this medication varies, depending on your insurance coverage,” said our Research Editor. “Some dieters have reported spending upwards of $200 for a 30-day supply.” [5]

One dieter stated, “Without insurance, my scrip would be $299 per month.”

According to another user, “It was $142 without insurance.” [6]

We found some Contrave reviews that didn’t mention the cost.

“Yes, it’s pricey, but I notice results,” said a consumer.

Contrave Side Effects – “Not Good!”

There is a list of Contrave side effects [7] available on the official website. One user commented, “I started two days ago and have felt very dizzy and throwing up to the point that I’m in tears.”

“I have started 10 days ago and I’m still fighting side effects (nausea, diarrhea, dizziness mainly),” said another.

According to some Contrave reviews, side effects are rare.

“I did have some of the side effects initially. I had dry mouth, dizziness, hot flashes and headaches. They all went away in the first two weeks,” stated a user.

“I have been on this Medicine for exactly 7 days. None of the side effects everyone talks about,” reported another. [8]

According to our research, if there is a small issue or problem with a weight-loss product, like side effects, that can negatively affect result and long-term dedication to a program. The official website openly published the potential risks of taking Contrave. As is the case with all prescription medications, the risks need to be weighed against the rewards.

The Science – “Clinically-Proven?”

There’s clinical studies conducted with the two key ingredients in Contrave. They’re proven effective in the medical treatment of depression [9], smoking cessation [10], weight-loss and other conditions. However, there are a couple roadblocks. You have to have a prescription and there are strict guidelines doctor’s have to follow before prescribing. Taking everything into consideration, we believe Contrave could be beneficial for some patients who are overweight or obese. Regular medical visits will be necessary during treatment.

The Bottom Line – Does Contrave Work?

Well now, what about this prescription medication for weight-loss? We like that Contrave is regulated by the FDA and that we found some favorable customer comments. We are concerned about customer comments relating to the high cost and negative side effects.

If you’re looking to slim down, we always suggest a supplement made with clinically tested ingredients shown to have the effect you’re looking for. It’s also nice if you don’t need a prescription or a loan from the bank.

Among the best products we’ve seen this year is one called Dietspotlight Burn. This supplement contains four clinically-tested ingredients, which have been shown to help accelerate fat loss and increase metabolism. Also, there’s no talk of harmful side effects and dieter reviews around the web show people are seeing solid results.

Plus, the makers of Dietspotlight Burn are so confident in their supplement, that they’re offering a Special Trial Offer.

Previous Contrave Review (Updated August 12, 2014):

Contrave: What You Should Know

2/2/2011 UPDATE: Today, the FDA rejected Orexigen Therapeutics Inc.'s Contrave pill, citing fears that the pill may increase heart risk. The FDA has not approved a new weight loss medication in ten years. The agency says it will evaluate Contrave again after Orexigen undertakes a costly new study examining possible links to heart risk. A spokesman for Contrave said that the company is evaluating next steps and deciding whether they will go through with the expensive study. Sorry, bad news for everyone who was looking to try this promising new drug.


12/9/2010 UPDATE: Today, the Endocrine and Metabolic Drugs Advisory Committee, a division of the FDA, has voted to recommend Contrave as a weight loss aid. However, the FDA still has to give the drug final approval before it can be distributed by physicians. The FDA takes sub-panel decisions such as this into consideration before approving any pharmaceutical drug. Like, the FDA will decide on approving Contrave for weight loss in January, 2011. However, the panel also recommends additional cardiovascular studies of patients prior to beginning sales based on case study findings, indicating that this product still may not be suitable for those with heart conditions. We will continue to update our review as more information becomes available.


Contrave is still in the testing stages, but it seems to offer great promise as a medication that will actually reduce the risk factors associated with obesity. Currently, this drug is in its third stage of clinical trials to assess the "safety, tolerability and efficacy", according to the company website. The company that is responsible for Contrave is Orexigen Therapeuticals, a biopharmaceutical company that is focused on creating drugs that treat central nervous system disorders, including obesity. Current studies are showing that Contrave can effectively reduce metabolic syndrome in many patients. Metabolic syndrome is a combination of risk factors that may increase the incidence of obesity, which can also increase the risk of heart disease and diabetes. This medication takes a whole new approach to weight loss, by focusing on neurological causes of obesity rather thansuppressing appetite or altering metabolic function. Opposite to the focusing on the mind, Phentermine suppresses the appetite, tricking the mind that the body isn't hungry.

List of Ingredients in Contrave

The two main ingredients that are being studied in the Contrave formula include Naltrexone and Bupropion. On the other hand an alternate product, Jadera Diet Pills concentrates on a bitter orange, cassia seed and mulberry leaf said to boost the metabolism and burn fat. Naltrexone has been used in the United States to treat opioid addiction since 1984, and in 1995 it began to be used to treat alcoholism as well. This drug inhibits the reinforcement of addictive substances by blocking opioid receptors to the brain, according to the Orexigen website. Naltrexone has also been shown to alter the taste of foods in numerous clinical studies. Aside from Contrave, IdealShape is a weight-loss system consisting of meal replacement shakes, snacks and supplements, and when paired with exercise there’s a good chance for weight-loss. Aside from this product, Neon Sport Thermo Rev is a thermogenic metabolism booster used to increase energy and promote weight loss.

Bupropion has been used to treat depression since 1985, and in 1997 trials were begun that experimented with the use of Bupropion as an aid to help quit smoking. This drug appears to be effective at suppressing appetite and increasing energy levels, and is the most prescribed antidepressant in the United States at the time of this review. One side effect that has been noted with Bupropion is weight loss; an attractive side effect for many indeed.

Product Features

Since this medication is still in the clinical trial stage, there are few product features to report. It is suspected that this medication will only be available by prescription, since it contains potent ingredients with potentially dangerous side effects. There is no pricing or customer testimonials at this time; however, ample clinical data is provided on the Orexigen website, and this info is comprehensive and professionally displayed. Aside from Contrave, some clinical research found with BiphedAdrene show rapid weight loss results from increased energy endurance.

Advantages of Contrave

  • The ingredients in Contrave may be effective in suppressing appetite and promoting weight loss.
  • Many clinical studies have been done on this product and are continuing at this time.
  • The company website contains ample information on the developmental progress of this product.

Disadvantages of Contrave

  • This product is not yet available to the general public at the time of this review.
  • The ingredients in Contrave may have potentially serious side effects for some. (See Contrave Side Effects).
  • May interact badly with other prescription medications.

Conclusion About Contrave

Contrave is worth keeping an eye out for, since the initial clinical studies have been promising and plenty of research is being conducted on the product. However, Contrave will not be the right choice for everyone, due to the possible side effects and medication interactions that may occur. Also, it definitely appears that Contrave will be prescription only, and will most likely be used to treat clinical obesity. It is important to talk to your doctor about whether Contrave would be a good choice for you.

Contrave is a prescription weight-loss medication that contains an anti-depressant. It is not unheardof for these drugs to be used for a variety of reasons like weight-loss and smoking cessation. You cannot purchase this formula in stores or online without a prescription.

Contrave Ingredients and Supplement Facts

Serving Size: Varies
Serving Per Container: Varies
Amount per Serving% DV
Buproprion Hydrochloride**
Naltrexone Hydrochloride**

Other Ingredients: None

We dug deep into the Contrave ingredients to give you the details you need.

Bupropion Hydrochloride

Bupropion hydrochloride is a prescription medication that goes by the names of Aplenzin and Wellbutrin XL.

What is it Supposed to Do?

It is used to treat depression and prevent seasonal affective disorder. There are other uses, including the treatment of attention deficit hyperactivity disorder[1] (ADHD), and smoking cessation. It may also be used with other mood stabilizers to treat bipolar disorder, and may be used to treat anxiety in people with depression. [2]

Clinical Research

There are a number of clinical studies available on this medicine, because it has been tested for FDA approval. One of the main side effects associated with Bupropion is weight-loss.

Naltrexone Hydrochloride

This medication is available by prescription only, and may also be marketed under the name Revia. It’s designed to treat opiate addiction, and used as part of a more comprehensive treatment program. The medication may also be used to treat alcohol abuse.

What is it Supposed to Do?

It works in the brain to prevent the affects of opiates – pain relief and feelings of well-being from taking place. It also works to decrease the desire to use opiates.

Clinical Research

There are a number of studies on this medication, though none are directly tied to weight-loss. According to a study published in Journal of Clinical Pyschopharmacology, “Although both groups showed decreases in smoking urge scores through treatment, the reductions were larger in the naltrexone group, with an average Brief Questionnaire of Smoking Urge scale score decrease of 13.6 ± 1.17 points in the naltrexone group compared with 9.58 ± 1.39 points in the placebo group (β [SE] = −4.37 [2.05], P < 0.05).”

Clinical research is an important part of the equation when it comes to choosing a diet supplement. You may want to take a look at a product like Dietspotlight Burn, which is formulated with clinically tested ingredients, and available without a prescription. Click above to learn more.

Contrave Side Effects:

As us true with all diet supplements, there is a chance of adverse side effects. In the case of Contrave, users have reported several troubling effects that should be considered prior to usage.


Nausea is a sensation of uneasiness that is triggered by the brain and centered in the stomach or abdomen Nausea is not itself a an illness but is a sensation that is felt. It occurs when the brain sends a message to the abdominal region that something may be awry. Nausea is nearly always linked to vomiting. [1]

What causes nausea?

Nausea can be caused by both slight and serious conditions. Nausea can occur due to motion sickness or from stress or anxiety. It can be brought about by medications, supplements or alcohol. It can also be a result of a problem within the brain or the circulatory system.


Every person has diarrhea from time to time. Diarrhea is watery, loose and frequent bowel movements. Diarrhea is often associated with nausea and vomiting. Diarrhea is when the intestines empty themselves in a defensive manner over concern for its contents. Excessive diarrhea leads to dehydration and can become life-threatening. [2]

What causes diarrhea?

Diarrhea can be caused by food poisoning, alcohol, medications, supplements, food allergies and lactose intolerance. Stress and anxiety can also be contributors. More serious causes include ulcers, cancer, obstructed bowel and IBS.


Dizziness is the sensation that you cannot steady yourself. It’s the feeling that either you or your surroundings are spinning or in motion. Dizziness comes from the brain and is a message that all is not right. The brain is crying foul and telling the body to shut down immediately. Typically, dizziness occurs in conjunction with nausea and vomiting.

What causes dizziness?

There can be many causes of dizziness including head injuries, brain tumors, or other debilitating diseases. Less severe causes can be the flu, food poisoning, alcohol, or adverse reactions to medications or supplements.

As always, consult your physician before taking any weight-loss product. In the case of Contrave, there are many side-effects that should be considered.

In the weight-loss market there are some prescription medications that require a deeper look, like Contrave. We took this opportunity to pore through Contrave side effects via ingredients and clinical research. We also found hundreds of comments and reviews to take into consideration. Then, we condensed and refined to give you the bottom line.

What You Need to Know

First off, Contrave is a prescription weight-loss medication comprised of naltrexone and bupropion. You start with one tablet in the morning and eventually move to two, twice a day. The formula is supposed to help dieters lose more weight. The pills are relatively small as is the bottle so you can take it with you during the day.

The medication, approved by the FDA in September 2014, is proven to help dieters lose weight, a good thing. You need a prescription to buy it at a pharmacy or online. We like that some users have seen positive results, but read on…

“Holy Warning Label!”

The first issue we have with Contrave side effects is the warning label. Common issues include nausea, dizziness, constipation, trouble sleeping, dry mouth, headache, diarrhea and vomiting. “When you choose a prescription medication for weight-loss there is a trade off,” says our Research Editor. “You have to work closely with your physician to decide whether or not the pros outweigh the cons.”

“Feeling tired, some nausea and dizziness. hope this will go away soon,” says a user.

“I have been on Contrave for over two months, I’m sick everyday. I can’t eat anything,” explains a dieter.

Some reported side effects were severe, “Second day made me seriously ill. Nauseous,twilight zone, dizzy and suicidal thoughts. NEVER will I take this again!!!!”

Contraindications -“We’ll Be Here a While!”

One of the scariest parts of Contrave side effects is that there are so many potential interactions and contraindications. When working through the positives and negatives of the medication you have to take these into consideration.

According to the Contrave prescribing information the medication “is contraindicated in people with hypertension…seizure disorder…alcohol or opiate addiction.” There’s also concern in patients with mental illness, suicidal thoughts, diabetes, high blood pressure, coronary issues of any kind and glaucoma.

Specific medications that interact with Contrave are lorcaserin, bupropion, phentermine, tramadol, trazodone and lisdexamfetamine. It is important to check with your physician if you are on anything before starting this treatment.

We’ve found through research, a connection between seemingly small issues, like contraindications, and a lesser chance of long-term success. If Contrave side effects and negative interactions make taking the pill worrisome for the dieter, it may not be the best option.

The Science

The FDA makes sure medications are tested on animals and humans before being approved for sale. Contrave side effects are also clinically proven. Though this drug is relatively new on the market, bupropion (one ingredient in the formula) has been around since 1989 so the potential reactions are well documented.

The Bottom Line

If you’re ready to shed those extra pounds, we recommend trying a product that offers clinically proven results without the side effects.

Among the best supplements we’ve encountered this year is Dietspotlight Burn. The formula is made up of a four-ingredient proprietary blend that’s clinically proven to help spark metabolism and accelerate fat loss. There are no reports of negative side effects, but we found numerous dieters speaking of excellent results.

The company behind Dietspotlight Burn is confident enough in the formula to be offering a Special Trial Offer, which is impressive.

  • References
  • 1. Nausea (2005). WebMD. November 1, 2016.
  • 2. Diarrhea (2016). Mayo Clinic. November 1, 2016.

Contrave Scientific Abstracts:

Bupropion Hydrochloride

Regarding both conduct issues as well as hyperactivity, there was a significant effect visible in the Conners 10 and 39-item teacher’s checklist as early as the third day. On day 28, there were significant visible effects on both conduct issues as well as restless-impulsive behavior (93-item parent’s questionnaire).  The results were found to be smaller regarding the parent ratings compared to teacher ratings. There had been substantial effects with treatment on both Continuous Performance Test as well as memory retrieval test. The magnitude of the consequences of bupropion and placebo were smaller within parent and teacher ratings than in standard drugs used in the treatment of ADDH. Bupropion had been found to be well tolerated in children, for the most part. Bupropion could be a helpful addition to treatments for ADDH, with an urge for further comparative trials using methylphenidate to solidify bupropion’s clinical merit. [1]

Bupropion blocks the re-uptake of dopamine and norepinephrine neurotransmission minus significant direct activities on serotonin neurotransmission. Bupropion has proven its effects as an antidepressant with comparable efficacy to other antidepressants. It is considered to be well tolerated for both short and long-term treatments with a headache, nausea, dry mouth, constipation, dizziness, and insomnia being the most common negative reactions. Some allergic reactions and seizures were reported, but rare. Bupropion has shown to have the lowest reports of sexual dysfunction, somnolence and weight gain in comparison to newer antidepressants on the market in the US. Bupropion is and will be a crucial part of major depressive disorder treatment in adults, among other related disorders. [2]

Naltrexone Hydrochloride

Any clinical data which backs up its use is extremely preliminary, suggesting further research before treatment can be recommended on a broad scale. Analysis from a plethora of basic and clinical research indicates that LDN has promising potential for being a treatment for chronic pain involving inflammatory activities. Dosing and other relevant parameters still require refinement. LDN could find itself emerging as the first glial cell modulators used in the treatment of chronic conditions, with the development of more certain medications in the future. [3]

Learn More About Burn HD »
Summer Banks Dietspotlight Author
About the Author:

Summer Banks, Director of Content at Dietspotlight, has researched over 5000 weight-loss programs, pills, shakes and diet plans. Previously, she managed 15 supplement brands, worked with doctors specializing in weight loss and completed coursework in nutrition at Stanford University. full bio.

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What are the side effects of taking Contrave?

Contrave side effects are dry mouth, headache, nausea and/or vomiting, diarrhea, constipation, dizziness and insomnia.

What are the ingredients in Contrave?

Contrave ingredients are bupropion HCL and naltrexone HCL.

How do I know if Contrave is right for me?

Choosing the right product is the #1 question asked by DietSpotlight readers. We recommend trying any product before buying it and know that finding a product with a sample offer is near impossible - so we created our own product, Burn HD, with scientifically backed ingredients.

Click here to get your sample of our powerful fat burner today.

Does Contrave work?

Yes, Contrave has been clinically proven and FDA approved.

How much does Contrave cost?

Contrave costs around $300 a month. The price could change after insurance.

How should I take Contrave?

You take one Contrave capsule in the morning for the first week. Then, one in the morning and one in the evening the second week. The third week you take two in the morning and one in the evening. Finally, by week four, you take two in the morning and two in the evening.

Who uses Contrave?

Individuals that are considered overweight or obese use Contrave. Your BMI has to be more than 27.

Can I stop Contrave on my own?

No, you can’t stop Contrave on your own. You will need to contact your healthcare provider prior to stopping this medication because of the potential for withdrawal symptoms.

What should I avoid while taking Contrave?

You should avoid using alcohol on Contrave.

What is the generic for Contrave?

There is no generic for Contrave.

Is Contrave a controlled substance?

No. Contrave is not currently a controlled substance.


If you’re looking for a weight loss supplement with a real guarantee, you might want to check out Dietspotlight Burn. It comes with a 120-Day guarantee and includes clinically researched ingredients.

Contrave Reviews

Leave a comment or review

  When should pill be taken

Should the pill be taken with food? When I take the pill at night what time should I take it? How early can I take it before bed?

Maribel (Editor)

Hi Jennifer. The recommendation is to slowly increase your dose over time to help you adjust to the medication.You should take one Contrave capsule in the morning the first week, one pill in the morning and another in the evening the second week (the exact time you take it is optional). On the third week, you will consume two in the morning and one in the evening. The fourth week and beyond, you will take two in the morning and two in the evening. Also, its best to consume with food or immediately after eating (yet, not with high fat meals).


I take my evening pill no later than 5 pm. I took it once at 8 pm and was up all night. My morning pill I take on an empty stomach at 6 am. I don’t have breakfast until around 7:15 am. Hope this helps.


I am getting ready to start Contrave next week. I am nervous about side effects. I am wondering if anyone has suggestions on meal plans?

Maribel (Editor)

Hello Joenesha. To reduce the risk of side effects, Contrave is prescribed on a step-up program. You start out low and work up to the full dose.

If you are not able to acquire a prescription, you might want to try other weight-loss products that contain natural ingredients; make sure to check out Dietspotlight Burn.


Patients should find out what their basal metabolic rate is and eat at least that many calories in a day. Eating less is not always the answer in many cases eating more may be the answer. Talking to a nutritionist or dietitian about caloric intake would be the best option.


I don’t count calories. I will only eat when my body signals me to eat. So I disagree with forcing food just to get the right amount of cslories

Lillian Ramsey

I have diabetes and high blood pressure and eye problems will contrive be a problem for me to take?

Victoria (Editor)

Hi Lillian! The list of contraindications for Contrave is long and detailed. The only person who can discuss possible issues with current medical conditions is your doctor. Sorry we couldn’t help more.

Claudia (Verified User)

i am on week one and no side effects. Wondering if I’m going to be able to sleep when I take it at night? Has anyone changed the dose to 2 in the am and none at night?


It does not keep me awake, it actually makes me sleepy.

Maribel (Editor)

Hi Claudia. Quite the contrary. Users have expressed feely sleepy when taking Contrave. Regarding the dose, its best to follow the product’s instructions thoroughly.


I have been off of Contrave for about 2 weeks because I was under the weather, can I start back up do I have to start my doses over?

Richard (Editor)

Hi Gegee. If you started at a lower dose and worked up to the dose you were taking before you were ill, give your doctor a call to see where you should start this time.

When will Contrave be available?
Lori Groleau

When will Contrave be available? I am very interested n finding out if it is right for me.

Glenn (Editor)

Hi Lori, Contrave is currently available but you would need a prescription from a doctor. However, if you prefer a product that you wouldn’t need a prescription for, you might want to check out Dietspotlight Burn. It contains clinically-tested ingredients and has been shown to help accelerate metabolism and boost fat loss.


I would like to try it but don’t know how much and is it worth it

  If stopped this, will I again gain weight ?
Idalia (Verified User)

I’ve been taking it for quite some time. Maybe 5 or 6 months and I’ve lost weight but that’s because I workout as well. My question is, once I get to my goal weight and I stop taking it, will I gain the weight back if I stop working out? I enjoy working out anyway, so I will continue but Im afraid of gaining all I lost back…does anyone know if this will happen? Thanks

kim (Verified User)

I just started week three of contrave. I’ve lost 5 lbs. so far. I’m not really exercising (I know I should) and the only real side effects for me has been a little nausea when I take the morning dose, head aches if I don’t drink a lot of water and constipation. It does do wonders for appetite control. Maybe a little too good, because I have to remind myself to eat.


anyone try just one pill a day at lunch? It makes me spacey and dizzy in the am.


Ani, I felt spacey and dizzy in the am as well. I have been eating before I take it, and I have felt 10x better! Hope this helps!

Soulmaiden (Verified User)

I have been on Contrave for 3 weeks now, and have lost 15 pounds. The sides effects were a bit hard to handle at first, but I got used to them and really don’t have them now. My only concern is how this medicine with with the kidneys. I have stage 3 kidney disease and worry it will cause a serious problem.

Montana (Editor)

Hi Soulmaiden. Contrave is a prescription medication. Your doctor would have to know about the stage 3 kidney disease before it was prescribed. If you didn’t tell the doctor, please call the office immediately and talk with the physician about any possible medical problems taking Contrave could cause.

Kim Dekenipp

I’ve been taking contracts for 2 weeks, not really seeing results yet. My question is can I take HCG with it? Also recommend a diet please . Thank you

Richard (Editor)

Hi Kim. HCG is only available by prescription and it is not prescribed for weight loss. Any HCG supplement that claims to contain real HCG is not telling the truth.

If you’re looking for diet recommendations, we work with people all the time to create personalized meal plans. Customer service can help you with that.

  I think it works wonderfully.
jonathan bowen (Verified User)

my dr. prescribed contrave for me and I have been taking it for one month with no adverse side affects. and I am losing weight while on the meds. it does cut your appetite. I don’t even think of eating my wife has to remind me to eat. I think it works wonderfully.


How are you doing now? I just got prescription and afraid of having seizures and side effects.


I have been on contrive for about 2 months, the first month I took it on and off not so good but then in the last 7 weeks I have lost 17.6lbs also doing weight watchers to keep me in control. I don’t think I have any side affects except If I eat a greasy meal I get bad stomach pains and in the bathroom Has this happen to anyone else?? Today I ate out with my nephew and I had an egg scramble with veggies and I think bacon was in it not sure what else. I had whole wheat toast.
ever since I have eaten that I have been sick.


HI Paula,
I’ve been on Contrave for about 6 weeks and I’ve lost 17.6 pounds. I had the opposite problem; it keeps me constipated to the point that I have to take a laxative every other day. Other than that, I haven’t experienced any of the other side effects that I’ve read about. Has anyone else had a problem with constipation, and if so, how are you combating the problem?


I had problems with constipation but I started eating prunes and that resolved my issue.

Sandee J (Verified User)

I was on the 52 week trail. I went from 190 to 129 & was advised to gain at least 6 back. shoud be 135 to 140. I am now 180 after being on an antideprssant. I can’t wait until it is approved so I can go back on it. IT WAS GREAT.


How long did it take to lose the bulk of your weight


What was the name of the diet pill you used and how did you get ahold of it?

I would like to try Contrave when it becomes available.

I would like to try Contrave when it becomes available.


Has anyone noticed while taking Contrave their hair thinning?



Victoria (Editor)

We checked the Contrave prescribing information and hair thinning wasn’t listed. If youy’re having this and believe it is a side effect of Contrave.

Leslie Doty

I have lost 30 pounds in a year and have kept it off. I have Fibromyalgia and it has lessoned and I do not have to take the prescription medicine prescribed for it as Contrave has helped with it (you could say two for the price of one). On the downside, the cost of Contrave is high even and after the trial period, I was paying about $60.00 and now I am paying $92.05 a month and my Insurance doesn’t cover Weight Loss. I am very Please with Contrave, but I haven’t lost anymore for several months.


My Dr. advised me that I will not lose any weight the first month. I did. That may have been in part that I told her I would walk at least two miles a day. I average five pounds lost per month. I have a waist line I haven’t seen in years. I had mild nausea the first few weeks on only a few occasions. I took a tums or nauzene. I have not had any side effects past that.

With my Rx, my Dr. gave me a card for Contrave. The card gave me a discount each month. I paid 99/one month or 291/three months. They asked if I wanted to join a program called scaledown, which they pay for. I received a very nicer digital scale, weigh myself daily, and then I receive encouraging text messages. Once a week I receive an email with my weekly and overall results.

I now find myself walking 4 miles a day on average. I walk during my one hour lunch and in the evenings. You can’t just take a pill, you have to commit to helping it work.


I have been taking contrave for almost 3 weeks. When I increased from 1 to 2 pills in the AM I started having bouts of itching. On my hands and feet mostly, now it’s the back of my neck. The itching isn’t constant but it is bothersome nonetheless. Anyone have this issue and if so what to do?


Yes, when I started the two pills I started itching after about 3 hrs later. After that my bottom lip started swelling. I took a Benadryl,didn’t work. I ended up seeing the doctor for a steroid shot .

M Love

Leave a comment…Sounds like an allergic reaction, stop taking the med and see your doctor immediately


I also had problems with the insurance company not accepting it at first; they wanted my doctor to call a special phone number so I was reimbursed the 98$ dollars for a supply of 120 tabs. The approval for the medication is good until April, but my doctor will have to request the refill.


I began Contrave last week. By the third day, I decided to take one in the a.m. and one by 2 p.m. I’m on day 7 and I’m up to three (mind you I’ve had to balance my Wellbutrin dosage to make what I was taking). Here’s what I’ve found- the first two days I had nausea, but only mildly and felt like I was “less” hungry. I’m also on the “Lose It” app as suggested by the doctor (the basic app is free). She’s not worried about my calories as much as my carb. intake, but the holidays were tough. I have no excuses now, today I’m ravenous and craving carbs. I don’t think I’ve lost any weight at all in the first week, but I’ve ramped up my intake from 1-3 in that short time. It’s very frustrating because my doctor says Zyrtec makes me gain weight and Klonopin doesn’t help my situation either. The Klonopin will be harder to wean off of, but I feel like I need it or I’ll never sleep. So everything is relative. I’d like to have success with this medication as I’m the one who researched it to match my Wellbutrin intake. I will give it two more weeks before I see her again to determine if this is right for me, but I just don’t know after one week and no results.




Ann my DR prescribed Contrave for me and I take 60 mg Cymbalta. Everyone’s different tho.


If your Dr. prescribes it at 2 different prescriptions….Wellbutrin/naltrexone, It doesn’t look like it is being used for weight loss, since my insurance doesn’t pay for anything weight loss related this works for me. I actually pay nothing for it 🙂


I was wondering if I continued with the Wellbutrin I am currently taking if I could just add the naltrexone. What amount of naltrexone did your dr. add for you?


Leave a comment… did this work the same as Contrave for you?


This is my second day of taking this drug, I was really worried about taking it because I don’t like taking any drug. The first day was fine but I did feel a little out of it, today I had no appetite at all I had to make myself eat something so I could take my morning drugs, so this evening I made myself something to eat because I haven’t eaten all day, well that was a mistake, I started feeling sick and so full like I hadn’t eaten a meal in a week. Because it’s the holidays I won’t be able to contact my doctor so I’m going to wait until the holiday’s are over before I take any more. Also the cost is really high my insurance will not cover it so I only brought 21 tablets and it was $45. At this point I’m going to see how it goes after the holidays and talk to my doctor about the side effects I don’t need any more problems.


I have been taking Contrave for 6 months and have lost 25 lbs. I paid 70. per month Now I am told I have to re enroll. I emailed the company and was told I could not register because I have Medicare. The cost with Commercial Insurance is 30.00 per month, the cash price if no insurance is 90.00 per month– but since I have Medicare I have to pay 228.05 per month and was told I can’t pay cash and get that cash price.. I am being penalized because being over 65 I have to have Medicare. Has any one else heard of this and what has happened to our free country?


Leave a comment…I just paid for my 1st prescription and it cost me $349.00 with private ins.
i am looking into ways to lower this cost.


today is Oct 6, i started taking Contrave May 12 weighing 200 lbs, 66 yrs old, female. I have lost 30 lbs with no ill side effects. All of a sudden, i want to snack. I want potato chips! I have never been a chip eater! I am up now at 2:00 am wanting and craving chips. Im fighting the urge, but it is hard! Im loosing sleep over this. I thought maybe it was my body telling me i needed salt! But i dont think so now! I have not lost any weight in 2 weeks (since ive started this potato chip craving). I didnt have any cravings since ive been on contrave–why now after ive been doing so well?


This is in response to “Libby” who suddenly had potato chip cravings…I had to laugh. I too have never been a ‘chip’ eater and for reasons unknown to me…suddenly crave potato chips.


Libby , Had to reply to this. I to have been having bad craving for potato chips. Never had I craved chips before. Before. Contrave, I was a big on sweets (chocolate). No more.

Your NameYEAH

I have been on contrive since mar 2015, lost from size 16 to 8 in about 6 mnts. the 1st 3 weeks I lost 11 lbs, but I did walk every day or every other day and watched my eating (no craving sweets at all, so I did not try, because this is a good thing), weight just started falling off fast. I started with the high mg and was not feeling well, contacted dr and he put me on their other lower mg 8/90 mg.. and I take 2 pills am and 1 pm ( I do not do the 2 and 2)No side effects at all. I have been able to stay at my weight gaining 4 lbs loosing them back, so my body plays with 5 lbs.. but the price in 2015 until sep 2016 was $70, then down to $58.00 a month, now it’s $93.00 (their new prices I was told) and this do not go down, it stays at $93.00 a month.. a little to expensive.. so after this month I will be going off the product, my question is if I keep up doing my exercise and eating as I know do, will the weight stay off or will it come back like other weight controls ..


Proud of you – amazing. Hope you keep up walking and I need to do the same. You guys have really got me thinking….


I’ve only been taking Contrave for four days and I’ve gained two pounds. No side effects just a little dry mouth. I will continue taking the correct dose. If I gain any more or at least don’t lose some weight then I will stop taking it.


I started Contrave in February, as of today I have lost 51 pounds. I would have lost more but a bad accident got in the way. I stopped taking it and I did not gain any weight back. I am very thankful for Contrave.


February of 2016?


I would like to pick your brain about your experience. Would you mind emailing me at lplasencia1@aol.com? Thanks so much!