Updated: 02/19/2018

Contrave Review - 11 Things You Need to Know


This review is what happened after I obsessed for weeks over Contrave. We decided to take an in-depth look at the prescription diet pill, side effects, ease of acquiring and clinical research. Additionally, we examined hundreds of dieter comments and testimonials. Then, we summarized and refined to give you the info you need.

Contrave can be purchased through Amazon.

Contrave Readers: Click here to find out why we're giving away samples of our product, Burn HD.

What is Contrave?

To start, Contrave is a prescription weight-loss medicine for individuals who have a BMI of 30 or greater or a BMI of 27 or greater with a medical condition related to their weight. This prescription drug (it must be doctor recommended) is designed to fight your appetite and to ultimately help you lose weight.

The ingredients are:

  • Bupropion HCI
  • Naltrexone HCI

Contrave claims to be weight-loss medicine designed to help dieters with both weight loss and weight management.

Contrave was approved by the U.S. Food and Drug Administration (“FDA”) in September 2014. [1]

If you have a tendency to rapidly gain weight, Contrave may help you keep it off.

Or, if you’ve been trying to lose weight the old-fashioned way or with another weight-loss pill, but to no avail, then Contrave may be the next step to try for results.

Contrave doesn’t treat medical problems like Type-2 Diabetes.

But, dropping weight may improve the condition. Studies show that there is an inextricable relationship between genes, weight and diabetes – among some other medical conditions. [2]


Contrave Competitors

Burn HD (Sample offer)read

Contrave Quick Facts


Takeda Pharmaceuticals USA, Inc, which is an offshoot of the biggest pharmaceutical company in Asia, Takeda Pharmaceuticals, and among the top 15 pharmaceutical companies globally.


In 2015, a lawsuit was filed against Orexigen, “a biopharmaceutical company focused on the development of pharmaceutical product candidates for the treatment of obesity, including Contrave, which it claims ‘regulates appetite and energy expenditure through [central nervous system] activity’.

“Orexigen was required to conduct a new, randomize-blind, placebo-controlled study to evaluate the effects of long-term treatment with Contrave on the incidents of major adverse cardiac events.

“On March 3, 2015, Orexigen disclosed detailed interim results of its study.”

In June 2015, Orexigen Therapeutics, Inc. and Takeda Pharmaceuticals filed a lawsuit against several companies collectively known as Actavis for infringement of the Contrave patent. [3] [4]


  • Revenue: ¥1,557,267 million (FY 2012)
  • Total assets ¥3,955,599 million (FY 2012)

Money back?

You can’t return Contrave.

Contrave Success Rates

Consumer Reports states that, “One of the largest clinical trials to date of Contrave shows obese and overweight people who took the drug for up to 56 weeks lost an average of 12 pounds (or about 5 percent of their body weight), compared with an average of 3 pounds (or 1 percent of their body weight) among those who took a placebo.

“Both groups were also put on a reduced calorie diet, exercised, and received behavioral counseling.

“In another study, obese and overweight people who took Contrave for up to a year shed an average of 18 pounds (or 8 percent of their body weight) while the placebo group lost 11 pounds (5 percent of their body weight).

“Both groups were also put on a reduced calorie diet, exercised, and received behavioral counseling. The result is that Contrave contributed to losing an additional 7 pounds.”

The report also clarifies that findings were even worse for diabetics: “Overweight people with that disorder who took Contrave for up to a year dropped an average of 9 pounds or 4 percent of their body weight, while those who took a placebo lost 4 pounds or 2 percent of their body weight. In that case, Contrave helped people lose only 5 additional pounds.” [5]

Does Contrave Work?

WebMD, on Contrave’s weight-loss effectiveness, reports: “In clinical trials that studied more than 4,500 people, the drug helped people keep off weight for up to a year, the length of the studies, according to Orexigen.

On average, those who took Contrave for 6 months and combined it with a weight-management program lost 25 pounds, the company says in a statement.

Those who were on placebo and the weight-management program averaged a 17-pound loss.” [6]

Professional Testimonials About Contrave

In the Journal of the American Medical Association (JAMA), Joshua Shafstein, who is the former FDA deputy director, and researcher Bruce Psaty have called for Contrave’s use to be restricted when Orexigen prematurely said it benefits the heart despite the fact that just 25% of the clinical trial was done (see “Lawsuits” above). [7]

Dr. Pieter Cohen, assistant professor of medicine at Harvard Medical School, researching the effects of dietary supplements, noted that Contrave would require a long-term commitment for very little weight-loss and studies are scarse on Contrave’s long-term effects:

“Even before thinking about the safety of the drug, it’s interesting to take a look at whether or not it’s going to be beneficial.

“The problem with Contrave is that we’re, first off, just talking about a very small amount of weight loss — just over 4 percent in clinical trials. So if you’re 225 pounds, we’re talking about losing less than 10 pounds if you took this for an entire year. If you stopped after a year of taking Contrave, you would very likely gain the weight right back.

“So if you wanted to keep that 10 pounds off for a long period of time, you have to take the medicine for presumably the rest of your life. And we don’t have any safety data regarding its long-term health effects.”
Dr Cohen was also critical of one of the two drugs that make up Contrave: “So the bupropion, which has been widely used to treat depression…is well known to cause seizures.

“In the pharmaceutical [company] supported studies that are being used as evidence that this medication is effective, more patients who received the drug experienced seizures than patients who received placebo. [8]

In addition, the findings of Lisa M. Schwartz, M.D., of Dartmouth College’s Geisel School of Medicine and the Institute for Health Policy and Clinical Practice, said, “The studies show that Contrave caused many people to feel sick”. Nearly 1 in 4 people in clinical trials stopped taking Contrave because of common side effects like nausea, vomiting, and headaches. [5]


Contrave Ingredients

To better understand Contrave, our research team took a closer look at the two main ingredients.

Bupropion Hydrochloride

Bupropion is also marketed as Wellbutrin and Zyban, among a few other names. It’s often prescribed as an antidepressant but when used in conjunction with other drugs its effects are different.

For example, it can be used to help you stop smoking and to prevent the effects of withdrawal. [9][10]

This ingredient is an appetite reducing drug that is meant to restore brain chemical imbalances and to keep users from overeating.

The Annals of Internal Medicine published an up-to-date meta-analysis showing that over a period of 6-12 weeks, patients may experience weight loss of 2.7 kg over placebo. [11]

While this may seem like good news, it’s worth mentioning that the effects of this drug on weight loss were similar to that of other drugs, like orlistat and sibutramine.

Naltrexone Hydrochloride

Naltrexone is classified as an “opiate antagonist.” That means it stops the activity of opioids and ultimately decreases the desire for opiates and alcohol. It’s marketed under trade names Revia and Vivitrol.

Naltrexone works together with bupropion on different parts of the user’s brain to decrease their desire for food, much like some other appetite suppressants.

Research from Pharmacy & Therapeutics concluded with, “Contrave may serve as a valuable treatment adjunct to lifestyle modifications by promoting satiety, reducing feeding, enhancing energy expenditure, and ultimately helping patients achieve weight loss goals.” [12]

In trials, nearly 50% of patients following the Contrave diet lost at least 5% of their body weight. So, if a patient weighs 300 lbs. (136 kg), 5% of that weight is 15 lbs. (6.8 kg).

On its own, that doesn’t sound like a lot, but compared to the placebo group, only about 20% of participants lost that amount of weight. [13]

RXlist reports that each tablet also each contains these inactive ingredients:

  • Microcrystalline cellulose
  • Hydroxypropyl cellulose
  • Lactose anhydrous
  • L-cysteine hydrochloride
  • Crospovidone [14]

It’s stressed that if you have any pre-existing health conditions or take over-the-counter or prescription medication to talk with your doctor before taking Contrave. This includes:

  • Any mental illness, including depression
  • Suicidal thoughts or behaviors
  • A head injury
  • Diabetes or low blood sugar
  • Liver or kidney disease
  • High blood pressure or heart disease
  • Drug or alcohol addiction

You should not take Contrave while pregnant or breastfeeding.

There have not been any reports of Contrave being addictive, but the issue that it would probably have to be a long-term drug to maintain the weight-loss makes this a moot point anyway.


Contrave Dosage

Contrave dosing usually starts small and increases over time at your doctor’s discretion. This is to lower the risk of seizures and other medical complications and side effects. Your dosage depends on several factors, including:

  • Medical conditions at the start of the treatment
  • The user’s response to the treatment
  • Other medications you may be taking

When you first start out taking Contrave, the doctor might prescribe just one pill to be taken in the morning, in order to acclimate your body to the new drug. Usually, around the second or third week you can start taking two pills: one in the morning and one in the evening – until you can handle taking four pills a day.

More specifically, Drugs.com says: “Contrave should be taken by mouth in the morning and in the evening. The tablets should not be cut, chewed, or crushed. Total daily doses greater than 32 mg/360 mg per day (two tablets twice daily) are not recommended.

“In clinical trials, Contrave was administered with meals. However, Contrave should not be taken with a high-fat meal because of a resulting significant increase in bupropion and naltrexone systemic exposure.” [15]

Most Contrave users seem to agree that the weight loss pill is best taken during a meal. [16] [17]

You should never change your Contrave dosing on your own. Do not stop, start, increase, or decrease the amount of Contrave you are taking without first consulting your doctor.


Contrave vs….

Drug Interactions

Contrave Drug Interactions

Alright, now is a good time to talk a bit about drug interactions.

A prescription weight loss medication like Contrave comes with warnings and potential interactions.

When following the Contrave diet, you should watch out for medications that may react negatively to the drug.

Your doctor should be able to fill you in on what you can and cannot take with Contrave.

There are several prescription and over-the-counter drugs that may affect or interfere with Contrave in the body, as well as change how effective Contrave and the other drug(s) are in the long run.

Some of these products include:

  • Narcotics such as codeine
  • Cough medicines
  • Diarrhea medications
  • MAO inhibitors

This last bit is very important. Because both MAOIs and Contrave affect a number of chemicals in the brain in different and overlapping ways, this can lead to a serious or even fatal reaction.

Taking both MAOIs and Contrave could be likened to starting a war—in the end, one of them is going to launch an atomic bomb in your brain.

The warnings for Contrave drug interactions also extend to other substances, such as recreational drugs e.g. marijuana and/or alcohol.

If you take Contrave with alcohol, you increase your risk of seizures.

The same is true if you drink alcohol regularly and suddenly stop in order to take Contrave.

You should talk with your doctor about changing the amount you drink before starting a Contrave or other weight loss pill regimen.

Side Effects

Contrave Side Effects

As if the incredible list of interactions and warning weren’t enough – let’s talk about the known side effects of Contrave. Contrave’s insert warns of potential side effects like manic episodes, visual problems and seizures.

Contrave side effects aren’t certain, but still worth considering. They include:

  • Dry mouth
  • Insomnia
  • Headache
  • Dizziness
  • Constipation
  • Diarrhea
  • Nausea
  • Vomiting
  • Chest tightness
  • Gas
  • Nightmares
  • Itching
  • Sleep disruption and insomnia
  • Mood and emotions affected (Contrave make you feel less hopeful and focused but more nervous)

Serious risks

  • Liver damage and hepatitis
  • Heart risks
  • Can affect hormonal balance
  • Suicidal thoughts or behaviors
  • Visual problems (symptoms include eye pain, changes in vision, swelling or redness in or around the eye)
  • Seizures

If you experience an allergic reaction to Contrave, stop taking it immediately and contact your doctor.

You could be allergic to either bupropion, naltrexone or both.



Contrave Benefits

Contrave offers a pretty sizable list of benefits, which include:

  • Weight loss
  • Weight management
  • More energy
  • Better overall health
  • Underlying conditions easier to detect and treat

As mentioned in the list, Contrave gives you energy.

Because the drug affects your central nervous system, it makes you feel restless, which could make you want to move around and keep busy.

This condition contributes to the insomnia side effect – often helped by activity or exercise.

Contrave gives you energy so that you will be able to burn more calories, reducing your weight and cravings for food.


Contrave Cost

For many people looking into life-improving products, the cost is an important factor in determining which supplement to go with.

The Contrave price depends on the number of pills you are taking. As time goes on, your doctor should slowly increase the amount of Contrave, so you’ll have to pay more.

The overall Contrave cost ranges from $55 per month to $200 per month.

It all depends on the amount, location (due to shipping costs), and insurance coverage you have.

However, Contrave gives the opportunity to sign up for a discount coupon plan for people whose health insurance does not cover the drug and those without insurance.

You could pay no more than $3 daily for a monthly prescription with this savings card. [21]

Bottom Line

The Bottom Line on Contrave

So here we are again. Staring into the face of a potential weight-loss solution and trying to figure out whether it’s even worth the money, time, or side effects. The ingredients are well-researched and shown to be effective – although not by much. A few issues we couldn’t escape include:

  • The list of warning and possible interactions are just frightening
  • It can become very expensive
  • Possible side effects are a bit too much for me

If you want to slim down and increase your energy levels, there are other supplements out there.

One of the best supplements out there is called Burn HD. It’s a proprietary blend of four ingredients, shown in published scientific studies to boost metabolism, increase energy and curb hunger. Our research team found positive reviews.

Additionally, we’re so confident that you’ll see results, there’s a 2-Week Sample going on so you can try it out for yourself.

Learn More About Burn HD »
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What are the side effects of taking Contrave?

Contrave side effects are dry mouth, headache, nausea and/or vomiting, diarrhea, constipation, dizziness and insomnia.

What are the ingredients in Contrave?

Contrave ingredients are bupropion HCL and naltrexone HCL.

How do I know if Contrave is right for me?

Choosing the right product is the #1 question asked by DietSpotlight readers. We recommend trying any product before buying it and know that finding a product with a sample offer is near impossible - so we created our own product, Burn HD, with scientifically backed ingredients.

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Does Contrave work?

Yes, Contrave has been clinically proven and FDA approved.

How much does Contrave cost?

Contrave costs around $300 a month. The price could change after insurance.

How should I take Contrave?

You take one Contrave capsule in the morning for the first week. Then, one in the morning and one in the evening the second week. The third week you take two in the morning and one in the evening. Finally, by week four, you take two in the morning and two in the evening.

Where can I buy Contrave?

Contrave can be purchased through Amazon.

Who uses Contrave?

Individuals that are considered overweight or obese use Contrave. Your BMI has to be more than 27.

Can I stop Contrave on my own?

No, you can’t stop Contrave on your own. You will need to contact your healthcare provider prior to stopping this medication because of the potential for withdrawal symptoms.

What should I avoid while taking Contrave?

You should avoid using alcohol on Contrave.

What is the generic for Contrave?

There is no generic for Contrave.

Is Contrave a controlled substance?

No. Contrave is not currently a controlled substance.


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Contrave Ingredients

Contrave is a prescription weight-loss medication that contains an anti-depressant. It is not unheardof for these drugs to be used for a variety of reasons like weight-loss and smoking cessation. You cannot purchase this formula in stores or online without a prescription.

Contrave Ingredients and Supplement Facts

Serving Size: Varies
Serving Per Container: Varies
Amount per Serving % DV
Buproprion Hydrochloride * *
Naltrexone Hydrochloride * *

Other Ingredients: None

We dug deep into the Contrave ingredients to give you the details you need.

Bupropion Hydrochloride

Bupropion hydrochloride is a prescription medication that goes by the names of Aplenzin and Wellbutrin XL.

What is it Supposed to Do?

It is used to treat depression and prevent seasonal affective disorder. There are other uses, including the treatment of attention deficit hyperactivity disorder[1] (ADHD), and smoking cessation. It may also be used with other mood stabilizers to treat bipolar disorder, and may be used to treat anxiety in people with depression. [2]

Clinical Research

There are a number of clinical studies available on this medicine, because it has been tested for FDA approval. One of the main side effects associated with Bupropion is weight-loss.

Naltrexone Hydrochloride

This medication is available by prescription only, and may also be marketed under the name Revia. It’s designed to treat opiate addiction, and used as part of a more comprehensive treatment program. The medication may also be used to treat alcohol abuse.

What is it Supposed to Do?

It works in the brain to prevent the affects of opiates – pain relief and feelings of well-being from taking place. It also works to decrease the desire to use opiates.

Clinical Research

There are a number of studies on this medication, though none are directly tied to weight-loss. According to a study published in Journal of Clinical Pyschopharmacology, “Although both groups showed decreases in smoking urge scores through treatment, the reductions were larger in the naltrexone group, with an average Brief Questionnaire of Smoking Urge scale score decrease of 13.6 ± 1.17 points in the naltrexone group compared with 9.58 ± 1.39 points in the placebo group (β [SE] = −4.37 [2.05], P < 0.05).”

Clinical research is an important part of the equation when it comes to choosing a diet supplement. You may want to take a look at a product like Dietspotlight Burn, which is formulated with clinically tested ingredients, and available without a prescription. Click above to learn more.

Contrave Scientific Abstracts

Bupropion Hydrochloride

Regarding both conduct issues as well as hyperactivity, there was a significant effect visible in the Conners 10 and 39-item teacher’s checklist as early as the third day. On day 28, there were significant visible effects on both conduct issues as well as restless-impulsive behavior (93-item parent’s questionnaire).  The results were found to be smaller regarding the parent ratings compared to teacher ratings. There had been substantial effects with treatment on both Continuous Performance Test as well as memory retrieval test. The magnitude of the consequences of bupropion and placebo were smaller within parent and teacher ratings than in standard drugs used in the treatment of ADDH. Bupropion had been found to be well tolerated in children, for the most part. Bupropion could be a helpful addition to treatments for ADDH, with an urge for further comparative trials using methylphenidate to solidify bupropion’s clinical merit. [1]

Bupropion blocks the re-uptake of dopamine and norepinephrine neurotransmission minus significant direct activities on serotonin neurotransmission. Bupropion has proven its effects as an antidepressant with comparable efficacy to other antidepressants. It is considered to be well tolerated for both short and long-term treatments with a headache, nausea, dry mouth, constipation, dizziness, and insomnia being the most common negative reactions. Some allergic reactions and seizures were reported, but rare. Bupropion has shown to have the lowest reports of sexual dysfunction, somnolence and weight gain in comparison to newer antidepressants on the market in the US. Bupropion is and will be a crucial part of major depressive disorder treatment in adults, among other related disorders. [2]

Naltrexone Hydrochloride

Any clinical data which backs up its use is extremely preliminary, suggesting further research before treatment can be recommended on a broad scale. Analysis from a plethora of basic and clinical research indicates that LDN has promising potential for being a treatment for chronic pain involving inflammatory activities. Dosing and other relevant parameters still require refinement. LDN could find itself emerging as the first glial cell modulators used in the treatment of chronic conditions, with the development of more certain medications in the future. [3]

Article Sources
Summer Banks Dietspotlight Author
About the Author:

Summer Banks, Director of Content at Dietspotlight, has researched over 5000 weight-loss programs, pills, shakes and diet plans. Previously, she managed 15 supplement brands, worked with doctors specializing in weight loss and completed coursework in nutrition at Stanford University. full bio.

171 Contrave Reviews

  • When should pill be taken

    Should the pill be taken with food? When I take the pill at night what time should I take it? How early can I take it before bed?

    • Marsha

      I take my evening pill no later than 5 pm. I took it once at 8 pm and was up all night. My morning pill I take on an empty stomach at 6 am. I don’t have breakfast until around 7:15 am. Hope this helps.

    • Maribel (Editor)

      Hi Jennifer. The recommendation is to slowly increase your dose over time to help you adjust to the medication.You should take one Contrave capsule in the morning the first week, one pill in the morning and another in the evening the second week (the exact time you take it is optional). On the third week, you will consume two in the morning and one in the evening. The fourth week and beyond, you will take two in the morning and two in the evening. Also, its best to consume with food or immediately after eating (yet, not with high fat meals).

  • Joenesha

    I am getting ready to start Contrave next week. I am nervous about side effects. I am wondering if anyone has suggestions on meal plans?

    • Kacey

      Patients should find out what their basal metabolic rate is and eat at least that many calories in a day. Eating less is not always the answer in many cases eating more may be the answer. Talking to a nutritionist or dietitian about caloric intake would be the best option.

      • Lorraine

        I don’t count calories. I will only eat when my body signals me to eat. So I disagree with forcing food just to get the right amount of cslories

        • Lisa

          I agree, Lorraine. I only eat when I’m hungry. Me forcing food is what got me in the shape I’m in now. I’m a food addict so forcing food would defeat the purpose of me taking the Contrave.

    • Maribel (Editor)

      Hello Joenesha. To reduce the risk of side effects, Contrave is prescribed on a step-up program. You start out low and work up to the full dose.

      If you are not able to acquire a prescription, you might want to try other weight-loss products that contain natural ingredients; make sure to check out Dietspotlight Burn.

  • Lillian Ramsey

    I have diabetes and high blood pressure and eye problems will contrive be a problem for me to take?

    • Anna (Editor)

      Hi Lillian! The list of contraindications for Contrave is long and detailed. The only person who can discuss possible issues with current medical conditions is your doctor. Sorry we couldn’t help more.

  • Contrave
    Claudia (Verified User)

    i am on week one and no side effects. Wondering if I’m going to be able to sleep when I take it at night? Has anyone changed the dose to 2 in the am and none at night?

    • Holliep

      It does not keep me awake, it actually makes me sleepy.

      • Maribel (Editor)

        Hi Claudia. Quite the contrary. Users have expressed feely sleepy when taking Contrave. Regarding the dose, its best to follow the product’s instructions thoroughly.

  • Gegee

    I have been off of Contrave for about 2 weeks because I was under the weather, can I start back up do I have to start my doses over?

    • Glenn (Editor)

      Hi Gegee. If you started at a lower dose and worked up to the dose you were taking before you were ill, give your doctor a call to see where you should start this time.

  • When will Contrave be available?
    Lori Groleau

    When will Contrave be available? I am very interested n finding out if it is right for me.

    • Glenn (Editor)

      Hi Lori, Contrave is currently available but you would need a prescription from a doctor. However, if you prefer a product that you wouldn’t need a prescription for, you might want to check out Dietspotlight Burn. It contains clinically-tested ingredients and has been shown to help accelerate metabolism and boost fat loss.

  • annette

    I would like to try it but don’t know how much and is it worth it

    • Summer (Editor)

      With the coupon from Contrave, you’ll spend about $3 a day. That’s $90 a month. If your insurance companies covers it, the cost will likely be lower.

      Is Contrave worth it? As a prescription medication it must be proven to work before the FDA will approve it. Contrave is a tool to help you stay on track and reach your goals. If that’s the kind of help you want, you can talk to your doctor.

  • NOT FOR ME!!
    JANELL Eaker (Verified User)

    I was given this medicine had HORRIBLE side effects ended up in emergency room on new years day, my legs was twitching so badly they wouldn’t hold still, had a hot feeling all over me , couldn’t do anything but throw up, this was the 1st tablet and ONLY tablet I’m taking never again! Janell Washington, IN.

  • Stopped Working
    Jean (Verified User)

    I have been taking Contrave for 90 days now. First 30 days i lost 14lbs, next 30 only 4lbs, and this last 30 days I lost NONE. I still don’t have much of an appetite and get full quickly. But it seems to have stopped working. Any ideas as to why or suggestions? At this point I am very discouraged. I kick box 3 days a week, so I am getting exercise. HELP 🙁

  •   Great luck with Contrave!
    Sharon (Verified User)

    I have been on Contrave for a year and have lost 35 pounds. I have exercised regularly the entire time and have had no issues keeping the weight off. My only noticeable side effect at the full dose of four a day was not sleeping well. I currently only take two Contrave in the morning and no longer have sleep issues. Contrave worked well for me and may not work for everyone but it’s definitely worth a try.

  • If stopped this, will I again gain weight ?
    Idalia (Verified User)

    I’ve been taking it for quite some time. Maybe 5 or 6 months and I’ve lost weight but that’s because I workout as well. My question is, once I get to my goal weight and I stop taking it, will I gain the weight back if I stop working out? I enjoy working out anyway, so I will continue but Im afraid of gaining all I lost back…does anyone know if this will happen? Thanks

    • Summer (Editor)

      Hi Idalia. There is a good chance if you stop taking Contrave and you stop working out that you will gain back at least some of the weight. Contrave is prescribed as a helpful tool you can use on a path to making life-long changes.

  •   kim (Verified User)

    I just started week three of contrave. I’ve lost 5 lbs. so far. I’m not really exercising (I know I should) and the only real side effects for me has been a little nausea when I take the morning dose, head aches if I don’t drink a lot of water and constipation. It does do wonders for appetite control. Maybe a little too good, because I have to remind myself to eat.

  • Ani

    anyone try just one pill a day at lunch? It makes me spacey and dizzy in the am.

    • Karen

      Ani, I felt spacey and dizzy in the am as well. I have been eating before I take it, and I have felt 10x better! Hope this helps!

  •   Contrave is not for me.
    Yvonne (Verified User)

    I took my first pill this morning and am very dizzy, nauseated, vomited once so far, shaky, clammy, and feel absolutely awful. I am praying all of this wears off very soon. I’m at work and hope I get better before I leave at 5 to drive my 40 miles home. 🙁 I won’t take this medication again.

  •   Soulmaiden (Verified User)

    I have been on Contrave for 3 weeks now, and have lost 15 pounds. The sides effects were a bit hard to handle at first, but I got used to them and really don’t have them now. My only concern is how this medicine with with the kidneys. I have stage 3 kidney disease and worry it will cause a serious problem.

    • Montana (Editor)

      Hi Soulmaiden. Contrave is a prescription medication. Your doctor would have to know about the stage 3 kidney disease before it was prescribed. If you didn’t tell the doctor, please call the office immediately and talk with the physician about any possible medical problems taking Contrave could cause.

  • Kim Dekenipp

    I’ve been taking contracts for 2 weeks, not really seeing results yet. My question is can I take HCG with it? Also recommend a diet please . Thank you

    • Andrew (Editor)

      Hi Kim. HCG is only available by prescription and it is not prescribed for weight loss. Any HCG supplement that claims to contain real HCG is not telling the truth.

      If you’re looking for diet recommendations, we work with people all the time to create personalized meal plans. Customer service can help you with that.

  •   I think it works wonderfully.
    jonathan bowen (Verified User)

    my dr. prescribed contrave for me and I have been taking it for one month with no adverse side affects. and I am losing weight while on the meds. it does cut your appetite. I don’t even think of eating my wife has to remind me to eat. I think it works wonderfully.

    • Sony

      How are you doing now? I just got prescription and afraid of having seizures and side effects.

  • Paula

    I have been on contrive for about 2 months, the first month I took it on and off not so good but then in the last 7 weeks I have lost 17.6lbs also doing weight watchers to keep me in control. I don’t think I have any side affects except If I eat a greasy meal I get bad stomach pains and in the bathroom Has this happen to anyone else?? Today I ate out with my nephew and I had an egg scramble with veggies and I think bacon was in it not sure what else. I had whole wheat toast.
    ever since I have eaten that I have been sick.

    • Tammy

      HI Paula,
      I’ve been on Contrave for about 6 weeks and I’ve lost 17.6 pounds. I had the opposite problem; it keeps me constipated to the point that I have to take a laxative every other day. Other than that, I haven’t experienced any of the other side effects that I’ve read about. Has anyone else had a problem with constipation, and if so, how are you combating the problem?

      • Kim

        I had problems with constipation but I started eating prunes and that resolved my issue.

    • Mel

      I’m on day 3 of Contrave and I too have experienced upset stomachs with this pill to the point that I have to run to the bathroom because I’m not sure I’ll make it. I was googling reviews on this to see if anyone else has experienced this and found yours. Besides this the only other side effect is feeling sleepy. I can deal with these side effects for now wondering what I have to look forward to as I increase my dosage. So far in these 3 days I have noticied a decrease in appetite.

  •   Antideprssant
    Sandee J (Verified User)

    I was on the 52 week trail. I went from 190 to 129 & was advised to gain at least 6 back. shoud be 135 to 140. I am now 180 after being on an antideprssant. I can’t wait until it is approved so I can go back on it. IT WAS GREAT.

    • cindy

      What was the name of the diet pill you used and how did you get ahold of it?

    • Sarah

      How long did it take to lose the bulk of your weight

    • Summer (Editor)

      Constipation is one of the more common Contrave side effects. Others include nausea, dizziness, headache, dry mouth and diarrhea.

      The natural way to fight constipation is with fiber, green leafy vegetables and water.

    • Lisa

      what was the name of the antidepressant and how did you get it?

  • I would like to try Contrave when it becomes available.

    I would like to try Contrave when it becomes available.

  • Amy

    Has anyone noticed while taking Contrave their hair thinning?

    • Paula


  • Leslie Doty

    I have lost 30 pounds in a year and have kept it off. I have Fibromyalgia and it has lessoned and I do not have to take the prescription medicine prescribed for it as Contrave has helped with it (you could say two for the price of one). On the downside, the cost of Contrave is high even and after the trial period, I was paying about $60.00 and now I am paying $92.05 a month and my Insurance doesn’t cover Weight Loss. I am very Please with Contrave, but I haven’t lost anymore for several months.

    • Brenda

      I also have taken Contrave for over a year now. I was losing abut a pound a month, but now that I am in my 14th month, I haven’t lost any weight. I don’t know what to do. Should I stop taking it.
      Leslie I also have to pay $92.05 and my insurance will not cover it.
      Any suggestions would be very helpful, I am thinking about stopping it since I am not seeing any results. I have actually gained a couple of pounds in the last couple of months and that scares me.

  • Tina

    My Dr. advised me that I will not lose any weight the first month. I did. That may have been in part that I told her I would walk at least two miles a day. I average five pounds lost per month. I have a waist line I haven’t seen in years. I had mild nausea the first few weeks on only a few occasions. I took a tums or nauzene. I have not had any side effects past that.

    With my Rx, my Dr. gave me a card for Contrave. The card gave me a discount each month. I paid 99/one month or 291/three months. They asked if I wanted to join a program called scaledown, which they pay for. I received a very nicer digital scale, weigh myself daily, and then I receive encouraging text messages. Once a week I receive an email with my weekly and overall results.

    I now find myself walking 4 miles a day on average. I walk during my one hour lunch and in the evenings. You can’t just take a pill, you have to commit to helping it work.

  • Tab

    I have been taking contrave for almost 3 weeks. When I increased from 1 to 2 pills in the AM I started having bouts of itching. On my hands and feet mostly, now it’s the back of my neck. The itching isn’t constant but it is bothersome nonetheless. Anyone have this issue and if so what to do?

    • M Love

      Leave a comment…Sounds like an allergic reaction, stop taking the med and see your doctor immediately

    • Chris

      Yes, when I started the two pills I started itching after about 3 hrs later. After that my bottom lip started swelling. I took a Benadryl,didn’t work. I ended up seeing the doctor for a steroid shot .

  • Cosmo

    I also had problems with the insurance company not accepting it at first; they wanted my doctor to call a special phone number so I was reimbursed the 98$ dollars for a supply of 120 tabs. The approval for the medication is good until April, but my doctor will have to request the refill.

  • Cosmo

    I began Contrave last week. By the third day, I decided to take one in the a.m. and one by 2 p.m. I’m on day 7 and I’m up to three (mind you I’ve had to balance my Wellbutrin dosage to make what I was taking). Here’s what I’ve found- the first two days I had nausea, but only mildly and felt like I was “less” hungry. I’m also on the “Lose It” app as suggested by the doctor (the basic app is free). She’s not worried about my calories as much as my carb. intake, but the holidays were tough. I have no excuses now, today I’m ravenous and craving carbs. I don’t think I’ve lost any weight at all in the first week, but I’ve ramped up my intake from 1-3 in that short time. It’s very frustrating because my doctor says Zyrtec makes me gain weight and Klonopin doesn’t help my situation either. The Klonopin will be harder to wean off of, but I feel like I need it or I’ll never sleep. So everything is relative. I’d like to have success with this medication as I’m the one who researched it to match my Wellbutrin intake. I will give it two more weeks before I see her again to determine if this is right for me, but I just don’t know after one week and no results.



    • Summer (Editor)

      Ann, the only person that can answer a medical question like this is the doctor who prescribed the Cymbalta. Contrave contains bupropion – an anti-depressant. Have a great day!

    • Tracey

      Ann my DR prescribed Contrave for me and I take 60 mg Cymbalta. Everyone’s different tho.

  • Lynn

    If your Dr. prescribes it at 2 different prescriptions….Wellbutrin/naltrexone, It doesn’t look like it is being used for weight loss, since my insurance doesn’t pay for anything weight loss related this works for me. I actually pay nothing for it 🙂

    • Charlene

      Leave a comment… did this work the same as Contrave for you?

    • deb

      I was wondering if I continued with the Wellbutrin I am currently taking if I could just add the naltrexone. What amount of naltrexone did your dr. add for you?

  • Dorothy

    This is my second day of taking this drug, I was really worried about taking it because I don’t like taking any drug. The first day was fine but I did feel a little out of it, today I had no appetite at all I had to make myself eat something so I could take my morning drugs, so this evening I made myself something to eat because I haven’t eaten all day, well that was a mistake, I started feeling sick and so full like I hadn’t eaten a meal in a week. Because it’s the holidays I won’t be able to contact my doctor so I’m going to wait until the holiday’s are over before I take any more. Also the cost is really high my insurance will not cover it so I only brought 21 tablets and it was $45. At this point I’m going to see how it goes after the holidays and talk to my doctor about the side effects I don’t need any more problems.

    • Summer (Editor)

      How are you doing Dorothy? Did Contrave work for you? We’d like to hear how your story has progressed.

  • Your Name

    I have been taking Contrave for 6 months and have lost 25 lbs. I paid 70. per month Now I am told I have to re enroll. I emailed the company and was told I could not register because I have Medicare. The cost with Commercial Insurance is 30.00 per month, the cash price if no insurance is 90.00 per month– but since I have Medicare I have to pay 228.05 per month and was told I can’t pay cash and get that cash price.. I am being penalized because being over 65 I have to have Medicare. Has any one else heard of this and what has happened to our free country?


      Leave a comment…I just paid for my 1st prescription and it cost me $349.00 with private ins.
      i am looking into ways to lower this cost.

  • Libby

    today is Oct 6, i started taking Contrave May 12 weighing 200 lbs, 66 yrs old, female. I have lost 30 lbs with no ill side effects. All of a sudden, i want to snack. I want potato chips! I have never been a chip eater! I am up now at 2:00 am wanting and craving chips. Im fighting the urge, but it is hard! Im loosing sleep over this. I thought maybe it was my body telling me i needed salt! But i dont think so now! I have not lost any weight in 2 weeks (since ive started this potato chip craving). I didnt have any cravings since ive been on contrave–why now after ive been doing so well?

    • Susanne

      This is in response to “Libby” who suddenly had potato chip cravings…I had to laugh. I too have never been a ‘chip’ eater and for reasons unknown to me…suddenly crave potato chips.

      • Lisa

        Libby , Had to reply to this. I to have been having bad craving for potato chips. Never had I craved chips before. Before. Contrave, I was a big on sweets (chocolate). No more.

  • Your NameYEAH

    I have been on contrive since mar 2015, lost from size 16 to 8 in about 6 mnts. the 1st 3 weeks I lost 11 lbs, but I did walk every day or every other day and watched my eating (no craving sweets at all, so I did not try, because this is a good thing), weight just started falling off fast. I started with the high mg and was not feeling well, contacted dr and he put me on their other lower mg 8/90 mg.. and I take 2 pills am and 1 pm ( I do not do the 2 and 2)No side effects at all. I have been able to stay at my weight gaining 4 lbs loosing them back, so my body plays with 5 lbs.. but the price in 2015 until sep 2016 was $70, then down to $58.00 a month, now it’s $93.00 (their new prices I was told) and this do not go down, it stays at $93.00 a month.. a little to expensive.. so after this month I will be going off the product, my question is if I keep up doing my exercise and eating as I know do, will the weight stay off or will it come back like other weight controls ..

    • Keegan

      Proud of you – amazing. Hope you keep up walking and I need to do the same. You guys have really got me thinking….

    • Summer (Editor)

      Yes….if you eat the same and workout the same you will likely stay the same weight or continue losing. Contrave helps fight hunger, though. So, you could notice an increase in hunger when you stop the medication.

      Never stop a medication without first talking to your doctor to be safe.

  • Jonelle

    I’ve only been taking Contrave for four days and I’ve gained two pounds. No side effects just a little dry mouth. I will continue taking the correct dose. If I gain any more or at least don’t lose some weight then I will stop taking it.

  •   Donna (Verified User)

    I have a question. I told Contrave for about 6 months and lost 27 lbs. I had absolutely no side affects. I went off of it because I had to revisit doctor for another prescription. I was off of it about 3 months. Now that I have started taking it again, I am not really seeing that it is as affective as it was before. Are there any other reports of this?

  • Marie

    I started Contrave in February, as of today I have lost 51 pounds. I would have lost more but a bad accident got in the way. I stopped taking it and I did not gain any weight back. I am very thankful for Contrave.

    • Luz

      I would like to pick your brain about your experience. Would you mind emailing me at lplasencia1@aol.com? Thanks so much!

    • Lisa

      February of 2016?

  • Laura

    I have been on contrave for 33 days and I have lost 20 lbs. I have no craving for snacks, sweets, or anything fried. I am now so motivated to exercise that I walk 2 miles a day. I had no side effects. I still have about 20 I’d like to lose. Contrave has changed my life.

    • julie

      What dosage were you taking when you lost the 20lbs in 33 days?

    • Summer (Editor)

      Amazing outcome Laura. Are you still taking Contrave or are you maintaining with diet and exercise?

  • Terri

    I am taking contrave and i am taking it once around seven in the morning and the other at one or two in evening so by time i go to bed i sleep fine and it is working for me no side effects

  •   It does its job of reducing apetite!
    Rosalind (Verified User)

    I’ve been on Contrave for a little over a month now. I have never had any of the side effects that are reported. It definitely does its job, which is to reduce your appetite. Within a week, I noticed that my eyes were definitely bigger than my stomach, and I’ve had to learn how to adjust my ordering out. I’ve lost about 10 lbs with not necessarily a healthy diet and working out about 3 times a week. I saw lots of up and down results, until the past 2 weeks, which was a steady loss. You definitely have to ride it out and see if it works for you. Listen to your body and stop when it’s full. This isn’t a fat burner pill, that just magically helps you lose weight, so when you do stop taking it, you won’t necessarily gain all of that back.

  •   8 days feeling horrible !
    Rachel (Verified User)

    i started taking Contrave 8 days ago and I just can’t get passed the side effects. I have felt horrible. Between the headaches, excessive tiredness, dizziness, and Nausea I have decided to stop taking this medication. I was trying to see if I just stop since I only took it for 8 days or if I have to do something else. I just can’t feel like this all the time.

    • Barb Rall

      I just took 1 week and to start on 2nd. I need to stop how do I do that?

    • Summer (Editor)

      Hey Rachel. Give your doctor a call. The Contrave dosage you’re on could be too high. If Contrave doesn’t come in a lower dose, doctors can prescribe the two ingredients separately. Hope this helps.

  •   Will start again soon !
    Heidi (Verified User)

    I started using Contrave last September, but stopped taking it after I got up to the recommended dosage of 4 per day. I lost weight, but once I was up to 4X’s per day, I started having horrible nightmares and quit taking it. I’ve since talked to my doctor about it and he recommended that I just take 1 per day. I will hopefully be able to start again soon.

  • Kim W

    I started taking Contrave yesterday and in the early evening I felt nauseated and had an upset stomach.
    Is this normal?

    • Victoria (Editor)

      Hello Kim. These are two of the most common Contrave side effects.

  •   It did not worked !
    M.T (Verified User)

    I have been taking contrave every since the first part of Jan.I have not lose a pound.I notices I have gain

    • C.P.

      I have been taking contrave for 4 weeks and I too have gained weight. Fortunately, I have not had any of the side effects I’ve read about. I do find that I am extremely sleepy sometimes.

    • Diane Patton

      I am on my 3rd week of Contrave and did not experience any side effects but have actually gained weight. I am going to stop taking Contrave. Now I have to work harder to lose the extra weight. Very disappointed!

  • Just started, feel nausiatic !
    Brianna (Verified User)

    I just started today April 28,2016 I feel a little difference right away my head kind of hurts, feel a little nausea , don’t feel hungry at all, I’ll post any updates on my journey taking this medication

    • Summer (Editor)

      We can’t wait for an update Brianna!

  • Week 3 - no major results !

    Starting my 3rd week – first week I lost 2 lbs along with eating proper along little exercise. The second week I gained it back with no exercise and my old eating habits. Im beginning to think week one was proper diet and exercise, not the pills. I wll see what week 3 brings. If no major results, I will stop taking it.

    • Kris

      I just wrote s big reply that ddnt go through for some reason, so I will keep this short. It is not an appetite suppressant or a stimulate. It’s designed to help you make better choices. Some people will be affected by the drug and some people. Some it will take longer to work and for some it starts working the first day no matter what, though, the math is still the same for us all, to achieve weight loss we must burn more calories than we consume, and we must be honest with ourselves about our exercise and our diet.

  • Judy porter

    Hello I’ve been on contravene almost 3 months , started out 184 now I’m 168 , but I’ve now started not being able to eat 1/2 my food , diarrhea , stomach cramps , feeling sick every time I eat , anyone else having these problems ?
    Now nothing taste good , I’ll order 4 different things just because my taste is off , and it was working so good .
    Also I’m on wellbrutin, does anyone know if that’s to much of what’s in contrave , did not want to tell my family dr. I was on contrave that was prescribe by another dr., Just trying to figure out if that’s to much of what’s in contrave & wellbrutin? And what would be the side effects ? Thank you judy

    • Anna (Editor)

      Judy, you must tell the doctor prescribing Wellbutrin that you’re on Contrave. Contrave contains bupropion, the generic name for Wellbutrin.

      Too much Wellbutrin can cause seizures. It can be very dangerous to take the two together unless carefully being watched by a doctor.

  • Theresa (Verified User)

    I will be starting week 5 tomorrow & while I really don’t have any side effects I have only lost about 1 lb. Does it take longer in some people? I am trying to stay within a 1200 calorie intake per day. I am getting a bit discouraged.

    • Adam

      Im on day 5 of Contrave, and combined with my nutritionists recommended diet, and exercise I have lost 12.5 pounds!!!! I feel great. I do have a bit of the nausea side effects but it’s worth it to me!

    • Kacey

      Theresa, I would definitely talk to your doctor about your daily intake. 1200 seems extremely low and may be the reason why you are not losing any weight. You should figure out what your basal metabolic rate is (the calories you burn sleeping or not moving just breathing). You need to eat at least this many calories for your body to survive and not going into survival mode or (hang onto every calorie mode). Hope this helps 🙂

  •   I have noticed difference in my cravings.
    natnurse (Verified User)

    2 week weigh in. I’m down 12 lbs. I just increased to 3 pills a day. I noticed some foginess but that subsided. I have definitely noticed a difference in my cravings. I was notorious for binge eating. I simply don’t have the cravings.

    Roberta (Verified User)

    I just began my second week on Contrave and am hungrier than ever. My stomach growls and no matter what I eat I am not satisfied. I wasn’t this hungry before taking the medication. Does anyone have any suggestions?

    Nichole (Verified User)

    I’ve been on Contrave for a month and a half. My side effects have been i get irriatable very easily. I’ve lost 18.9 pounds.

  • linda Mushen

    I have been taking contrave since late Jan 2016 I started out fine, no issues but now I have nausea all day and feel sick. What can I take for the Nausea its horrible, I have lost 13 pounds but and going to stop taking pill if I cant get relief , I do sometimes feel sick too when eating something in healthy or greasy or any sugar.


      Ginger is a natural cure for nausea

  • Sara

    I started my first pill today. About two hours in a started to feel very hot and sick to my stomach , my pupils are very small and alittle light headed

  • Dana Lee

    I don’t like Contrave first it cost to much and it is not helping me at All I am gain weight instead of loosing , I did have hot flashes and trouble with my bowels it don’t t work at I would like to get my money back, I am not satisfied the this product and dry mouth, I have been on it for 3 weeks

  • Bev

    For the first few weeks in taking this medicine I had some side effects like agitation and strange dreams and almost stopped taking it, but stuck with it and the bad side effects subsided and was replaced with a good side effect which was “lack of appetite”. In 4 months I lost 40 lbs., but took a month off and gained 5 back. I just went back on it again this past week and lost 1.5 of those pounds.

  • I take my pills and I get dizzy
    Cecilia (Verified User)

    My hands shake when I take my pills and I get dizzy. Is this normal?

  •   the worse thing ever that happens
    Ricado (Verified User)

    first week terrible headache and waking up many times during the night with weird dreams, then headache went away the second week my mood went down the toilet I couldn’t Perform at work and really irritable with little things , got hungry and craving sweets , constipation , the 3rd week at 2 pills in the morning and 1 in the afternoon at the 3rd day I had enough , became a different person and had to stop in other words I got depressed that never happens to me ever , this med work totally the opposite with me , the worse thing ever that happens to me

  • Your gail homer

    Tell us your thoughts about Contrave.it seems very expensive an has a lot of side effect

  •   Helped me a lot !
    Laura (Verified User)

    I started Contrave 3/14/16. I had slight nausea but I would eat a cracker and it would go away. I had headaches but would take Excedrin and it would go away. Contrave has helped me a lot. I have lost 15 pounds, I have gained 2-3 pounds but I believe it was due to monthly female issues. I was craving sweets that week but today I do not have the sweets craving. I am looking forward to continuing this medication and losing weight.

  •   pretty awesome i feel great
    Remy (Verified User)

    Started using contrave on 1/8/2016 i was 259 pounds as of today 1/20/16 i weigh 239, which is pretty awesome i feel great first day side effects was throwing up but that went away quick

  • Savannah

    I started taking Contrave on April 26th of this year. As of today(7/13), I have lost a total of 33lbs! I exercise moderately and eat a healthy diet, which I did before starting Contrave. I also paired the use of Contrave with the ScaleDown program that is made available for those taking Contrave. In addition to my weight loss, I have also been able to quit smoking in the process! The worst side effect I have experienced was severe stomach cramps. They weren’t constant, and usually happened in the middle of the night. After speaking to my doctor about it, we concluded that the cramps were mostly present when I didn’t eat as much as I should for that day. I must admit, before I began taking Contrave, I was incredibly nervous because all of the potential side effects were terrifying! The key here is to know that you have a doctor who knows you and your medical history well and who is also familiar with Contrave and how it’s side effects could potentially apply to you.

  •   Product was not good for me
    Michelle (Verified User)

    Was on it for 3 mo. Im in my mid forties, go to the gym 4 days a week. 5 ft 5 190. Healthy ithet than needing to lose some weight. The fatigue on this drug wqs incredible. I almost fell asleep at the wheel twice. The last few weeks I was irritable, slightly depressed, a little manic and became almost hostile. Ive never had a history of depression. The nausea and dizziness came and went here and there but the neurological side effects were too much for me. If it works for you great for me it couod have been deadly

  • Anyone having the same eye effect?
    Cheryl (Verified User)

    I am giving this 3 stars because I only started Contrave a week ago. I think I lost about 3 lbs. I’m definitely less hungry. Hasn’t yet curbed the cravings. I woke up this weekend with a subconjunctival hemorrhage (bloody spot on my eye). Has this happened to anyone else. I have never had one in my 48 years

  •   So far feels great
    Carol Bailey (Verified User)

    I just started Conrtave on September 5,2015 no side effects, eating less food, no sweets and feeling great.

  • Wants to have a free sample
    Your Name

    Me too! I would like free samples as well. My doctor had me on phentermine for a month, and I lost 12 lbs! I loved it, but now I may have to switch to contrave & I’m a little weary.

  •   Working good so far
    Greg (Verified User)

    Took contrave for 3 months lost 80 pounds, almost 1 pound a day. Had to stop for a month to ck elevated liver enzyme, also stopped Lipitor had an ultrasound everything good. Started back 6 days ago with 2 pills a day, not the 4 I was taking. I was off contrave for a month during that time I fluctuated between 243 and 248 still walking 3 to 5 miles aday but kept falling off the wagon, gain some weight lose it gain it back. After July 4 went to 250 then July 6 252.2 called doctor for ultrasound results. After the good news asked to start contrave again he said yes but 2 pills a day not 4. This morning 237, 91 pounds lost” working for me. I had more reaction to the drug starting back than when starting contrave the first time. The first 2 days starting again had 2 very sleepless nights 1 headache day but everything good last few days. Have more work to do another 50 pounds but in so much better shape now blood pressure very good.

    • Carmen

      Oh Greg! I know how you feel!! I started Contrave the first week in May 2015 and had very little side effects. Started week two with 1 at night, 1 in morning and the nausea was awful!!! I honestly felt that the reason I was losing weight was because of the insane nausea. It did come and go in waves but was awful when it hit!! So instead of increasing to three the next week after, I took two pills for 2 weeks then started my 3 pills a day without trouble. Was very happy about that! Then I began week four….OMG! The ringing in my ears….the dizziness….felt terrible!!!! Vertigo was unreal. For nausea I was taking Dramamine which became a daily med for me to combat the nausea so I tried Bonine to combat the vertigo without any relief. I immediately went back to 3 pills and was doing great! My weight went from 211 to 176.00 by November 2015. I was eating a very low-fat diet and walking daily for 30-45 min. I was feeling great! Then Dec.10th I tore my left hamstring. Massive pain! That day I had to stop Contrave immediately because I was put on a codeine based med which you cannot take with It. My weight ballooned up to 198 but by March my hamstring healed and began my regimen of pills in April after the necessary two week break from pain meds. My Lord, this second time has been HORRIBLE!!!! I had no idea just how sick to my stomach this med makes me but quickly remembered when attempting my two pills a day. Now not only did I get shaky but very, very nauseous with just two!!! The break from this medication what’s necessary for me but I just wish I didn’t have to have stopped then begin again. It’s really not a good feeling… However, I did lose weight, did adjust after the first go-round and used Dramamine for nausea because phone regain is contraindicated with this medication. The hard time I’m having now may be that I’m not following a completely low-fat diet right now and it is May 2016 and I haven’t walked regularly since December 2015. I’m going to give it another go because I backed down to only 1 pill a day now. So I may want to ease back into it. My recommendation is to exercise by walking at least 30 minutes a day, eat a low fat diet and use Dramamine if nauseated. It helps so much. Oh! And keep those liver enzymes in check…no alcohol! I pray I can continue on with this medicine!!! One HUGE benefit was that it totally took away my cravings for food….many a day I had to force myself to eat!! But there again, the nausea played a role in that as well….*sigh. Good Luck!!!

  • Should I increase the dosage?
    New2Contrave (Verified User)

    I just started taking Contrave 1 week ago today. My DR prescribed me to start 2/day, but in fear of the side effects, I started out only taking 1/day. I have not noticed ANY benefit. It hasn’t helped curb my appetite at all and I find myself even over-eating more than normal. Will the medicine work better when I increase my dosage to 2/day?! I hope so!! I was on Phentermine for 4 months and lost 30 lbs. I wish you could take that long term. It worked wonderfully.

    • Ckew

      There is a prescription discount card that comes with your Rx. It is from Contrave. If your insurance does not cover. Your first 2 refills are $70. The 3rd on, it is $60.

      • Your Name

        Depends on what insurance you have i didnt qualify for the discount card i had to pay $220.00

        • Ashley

          Everyone gets the discount. You have to go to the contrive website and register/download your contrive card. it will bring the medication down to either $70, or $55 for the first 2 months. Then it drops $10 after the 3rd month.

          • Lisa

            I went to website I registered n got my discount card but still was charged $90.

            • Linda Lee

              I had the card and downloaded it, too. But I still had to pay $90. That’s expensive.

            • Mary Lou

              I paid $90 dollars also. Been on for two days and I am never hungry so make myself eat. I am being very careful about fatty foods. Protein, veggies and fruit. Also potatoes even though I know it would be better to stay away from them. I have lost a couple of pounds but I attribute that to water. Hoping for good results.

              • Krystal

                I just bought it yesterday and paid $90

    • Your Name


      • jackie

        I went to the web site and printed the paper! No discount for me …has to be 70 pills Dr will only give 30
        Day supply??! Where is the discount card please!

  • Have lost 12 lbs.
    Jeff (Verified User)

    Have been on Contrave for 3 weeks. Have lost 12 lbs. Cravings are gone for food and alcohol. Eating is becoming something that takes up my time and would rather not do.

  • eat really healthy and no fast foods

    I’ve only lost 10 lbs in 2 and half months is that normal? I eat really healthy and no fast foods or pops I walk 3 to 4 miles a day and do yoga

    • Adrian (Editor)

      Hello Rina. All dieters have different weight loss results. Some users lose weight faster/slower than others.

  • had to force myself to eat something

    I just started today 1pill week1 2-wk2 i was afraid to start because I had been on an opiate.but day 1 went fine.No side affects and no appetite.had to force myself to eat something.

  •   ramping up the dose
    BeachGirlNC (Verified User)

    I have been ramping up the dose from 1/day to 4/day over the last 4 weeks. I have been nauseous with a headache for at least 5 days following each added pill. I want to stop nearly every day but have hopes that now that I am on the full dose that my body will adjust and I will feel better. As I read these reviews I want to know how many people started with the full dose and who ramped up like me. I have not lost any weight nor have I had any added energy. My only appetite suppression is due to my nausea. I feel positive in seeing other reviews and hope the next week brings some improvements.

    • Marcia Hartgrove

      I have been on for 3 months & have lost 18 lbs. I talked to my Dr. yesterday about the nausea which seems to have gotten worse with the increase in dosage. She told me it was ok to cut back to only 3 a day to see if that helps. I noticed others have stayed on a lower dosaage. If it does not work on the lower dosage, I can add another one.

      • Sara

        I just started today and the nausea was horrible. I told my dr she said to stay with the 1 pill until that side effect is gone.

  •   Highly recommended product
    Doris (Verified User)

    Hello, I’m on week 2 of Contrave and it really does work I don’t crave for sweets I focus better I felt dizzy only one day, all because I had no appetite and did not eat but after I consumed food I felt find. You really get full faster….. I recommend this pill

  •   contrave for two weeks
    natalina (Verified User)

    I’ve been on contrave for two weeks still taking 1+1. the dizziness still hasn’t gone away. I’ve lost 8 lbs. in the two weeks with diet and exercise. im kind of scared to take the recommended dose of 2+2. any advice?

    • Adrian (Editor)

      Hello Natalina. If you continue to have these side effects, please consult with your physician before continuing this diet.

    • Nicole

      Hello~ I was doing very well on the 1&1 dose, lost 11 pounds since march 14th. The day after I increased my dose per the dosing schedule to 2 & 1 I woke up with an allergic reaction. Red bumps on my arms, legs, stomach and red around the eyes. I went back to the 1:1.

  •   no side effects except for some days
    Melyssa (Verified User)

    I’ve been taking contrave for almost 5 weeks now and have lost 17 pounds, I have no side effects except for some days I’m a little tireder then others. but other then that this pill has been my wonder blue pill and I have been very pleased with the results. Oh yeah I do spin classes 6 days a week and watch my food intake, although I’m not very hungry with the pill. Hope my experience helps.. 🙂

  •   This product did not work for me.
    Kathy VonSeggern (Verified User)

    I’ve been on Contrave over 2 moths I still weigh same
    I drink 2 was water minumim a day
    Ever size every day 20 min cardio
    30 min weights

  • having problems with light headed

    I have been on it for almost a month, I was having problems with light headed and dizzy increased my water intake and it seems to have subsided. Good luck

  • Cyn

    I started taking it since easter 2016, I weighted 150lbs, 5″6, it’s been 1.5 months and lost about 12 lbs (138lbs now). I stoped for a week since I went to Vegas.

  •   So far, so good.
    Amy G (Verified User)

    So far, so good. I am just finishing up week 2, 1 + 1… No side effects and I am beginning to notice a decrease in appetite and cravings, I think!

  • absolutely sickened me
    Irene Hecht (Verified User)

    I have been on Contrave two weeks. I have had to stop taking it because it absolutely sickened me. The most foul metallic taste in the mouth coupled with constant nausea was more than I could bear. It reminded me of my bout with chemotherapy. In fact the side effects were so similar. I am truly sorry and disappointed since I truly had high hopes of being successful with the help of this medication.

  • Just picked, excited start !

    Just picked up my prescription yesterday. My co-pay was only $15 for 120 pills. I’m excited to start these.

  • How long it take to lose weight?

    Lisa, how long did it take to lose the bulk of your weight

  • Lisa, how long did you lose 40lbs?

    Hi Lisa for hw long did you lose 40 pound

  •   Product work but quite expensive
    M R (Verified User)

    I have been for five weeks now I have not experienced any side effects and I have lost 23 pounds. Of course diet and exercise Is very important. Contrave helped curb the appetite and took the cravings away I can very easily choose to say no thank you to A piece of cake. And yes without insurance it is quite expensive . I wish insurance companies would understand people losing weight and less money will go into keeping them healthy.

  • I hope it works for me.
    Tanya (Verified User)

    Mines is 57 a month ..just got it today …I hope it works

    • Sarah

      Hi I just sent off for mine 2 days ago, how are you doing on yours?

      • laurie

        How is it going so far my Dr just prescribed this for me but have not received it yet

      • valsab

        I have started 10 days ago and I’m still fighting side effects (nausea, diarrhea, dizziness mainly). No effect I can see yet but I’m only taking 1+1 right now. How are y’all doing?

      • VTobar

        I started two days ago and have felt very Dizzy!!! and throwing up to the point that im in tears…just wondering if your side effects have gone away?

        • Jamie

          I am relieved to hear that I am not the only one who has had the dizziness and feel g very shaky and nauseated. I am on week three and have lost 12 pounds. It is very important to remember to eat, I also do not feel hungry most of the time and when mealtimes come along I eat way less than I used too. 12 pounds down so far!

    • Patti

      Where did you get contrave for 57 a month? How are you doing on it?


        Ask your Dr. for the coupon I paid $55

      • Your Name

        My cost is $30/month as my insurance covers it.

  • i am not on medications

    i would like to try concave .wold like to loose some weight i am not on medications i dont have high blood pressure dont have heart disorders .I do exercise and my thyroid is great dont know y i cannot loose i eat healty and small portions

  • before it hits the market.
    Cindy Johnson

    Please keep me in mind if you are looking for volunteers to try Contrave before it hits the market.

  • high blood pressure,
    Kathy Schwab

    I would like to know about Warfarin and this product, along with medication for diabetics, high blood pressure, pain meds for chronic lower back pain, Effexor RX, acid reflux med., and about 180 LBS. needed to lose

  • new chack with your Dr,

    it s on today but can t find much more still new chack with your Dr, asap

  • side effects vs my psychological state
    Barbara (Verified User)

    I began Contrave a week before I had a traumatic experience and suffered from severe depression and PTSD — so I’m not quit sure what to consider side effects vs my psychological state. I vomited once a day for the first 2 weeks (likely contrave). I was hungry, but just didn’t feel like eating (could be either – likely both). I had some irrational behavior that was very much out of character. But now it’s been 10 months, my mood is better and stable, I still vomit once every few weeks. My appetite is back (more cravings than hunger), I lost 25 pounds and the first few months, and a total of 38 pounds over the 10 months (24% of my body weight). My weight has been stable for months +/- a pound. For me it was worth whatever side effects could be contributed to the med. My self-esteem is so much improved. Not only was I dieting and exercising before the med and not losing weight — I was continuing to gain. This was my salvation.

  • Shawn

    What is Contrave prescribed for?

  •   I too was in the study
    Renee (Verified User)

    I too was in the study. It was wonderful. I could look at something temping (like cookies, candy ect. and say no thank you.) Trust me, that has never happened in my life! I lost 30 lbs and never gained it back. I still can’t wait for it to come out. I still have a lot of weight to loose.

  • Julie Byrd

    I owuld be interested in being a part of the clinical trial also.

  • I think it's too late

    I am very interested in being part of the clinical trial too but I think it’s too late. So I just want to know when it will be available on the market. Thanx 🙂

  • Trial study
    Fred Reeves

    interested in being part of trial study

    • connie

      Great so far!! Yeah i hope they do put me in study…when my scales.get.here

  • Had work

    let me know when it come out cuz i try everything and nothing had work…thank you

  • I am hoping this product will work

    Great news ! I would also like to be part of the clinical trial. I used Phen-Phen and lost the weight but gained back when stopped. I am really hoping this product will work for me and be also safe, I am so very tired of being overweight, I am trapped in this big body when inside I’m thin, healthy and happy…