Updated: 01/11/2018

Dexedrine Review - 6 Things You Need to Know


A diet product’s worth depends on whether it actually helps people lose weight. Let’s find out if Dexedrine really works. We dug deep and created a comprehensive review, examining the side effects, ingredients, level of customer service and clinical research. Plus we scrutinized dozens of user responses and comments that are posted online. At last, we summed up all of the facts and feedback to give you the bottom line.

Dexedrine Readers: Click here to find out why we're giving away samples of our product, Burn HD.

What You Need To Know

First off, Dexedrine ingredients include dextroamphetamine sulfate. Put simply, this is an FDA-regulated controlled substance. It’s classified as an amphetamine. Furthermore, it works as a stimulant to affect the central nervous system. Typically this drug is prescribed to patients with ADHD or sleep disorders like narcolepsy. This is because it helps improve attention span. However, it is sometimes used to treat obesity. Unlike over-the-counter weight-loss supplements, this product must be acquired through a licensed physician. Also, it must be taken in accordance with your doctor’s directions.

The company behind Dexedrine is Smith Kline. It was first released in the US back in 1952. This drug may help reduce appetite and boost energy levels. Furthermore, it is regulated by the FDA, which means clinical studies have been conducted, but read on…

Side Effects – “Is It Safe?”

The first concern was the adverse reactions reported by customers. According to our Research Editor, “Dexedrine side effects include fast heartbeat, dry mouth, tremors, upset stomach, dizziness, headache and trouble sleeping. Some people even experience more severe effects such as seizures, blurred vision and allergic reactions. This is stated clearly on the official website.”

One user stated, “I have been taking 15mg of Dexedrine for weight-loss for two weeks now. The last three days I have had sore eyes, tightness in my face and a plugged feeling in my ears. Had a hard time sleeping last night. I am concerned.”

Then again, a different person said this, “Definitely helps reduce my appetite.”

Another commented, “It keeps me alert. Not sure about the weight-loss yet.”

User Complaints – “Uh Oh”

There are certainly some user complaints posted on the web for Dexedrine. One person reported, “This drug is not worth the side effects. Too extreme. It does reduce my appetite, but can’t stand the heart palpitations and anxiety.”

On the other hand, not all users complain about Dexedrine. One customer posted, “I have already lost a few pounds. It does give you a boost and reduce hunger.”

Another revealed, “If you can stand some side effects, it will help you shed some pounds.”

The extensive research we’ve done has shown if there is a specific part of a diet pill that is quite concerning, like causing negative reactions, the likelihood of long-term success is slim. This means if Dexedrine does in fact lead to unpleasant adverse effects in a lot of people, this might be a deal breaker.

The Science – “Solid?”

There is some clinical research presented on Dexedrine. After all, this is a controlled substance that is regulated by the FDA. Moreover, some studies have shown that it can help treat obesity on some level. However, you must keep in mind that this diet pill is not suitable for everyone. Furthermore, the side effects may outweigh the benefits.

What Users Are Saying

“”This is a great product! It helps me maintain concentration without making me feel jittery. The best part is that it is natural.””

“”Do they help you focus? Sort of. All they really do is wake you up a bit.””

“”While I did not have very high expectations from the beginning, I am disappointed that it did not produce at least a noticeable improvement on my memory, concentration or energy.””

The Bottom Line – Does Dexedrine Work?

Now the moment you’ve been waiting for. This is our bottom line on Dexedrine. First off, we appreciate that this drug has been clinically tested. It’s also refreshing to see that this weight-loss aid is regulated by the FDA. On the other hand, we’re leery about this product because it can lead to several unpleasant side effects. Furthermore, there are some user complaints posted on the web. Not to mention, many people will not be able to get a prescription for this obesity drug.

If you really want to drop more pounds, then we encourage you to choose a diet product that contains clinically tested ingredients for weight-loss, does not cause any unpleasant side effects and is easy to purchase online.

Among the best products we’ve seen this year is one called Burn HD. This supplement contains a proprietary blend of four key ingredients. Some of which have been shown in published clinical research to help boost metabolism and increase fat loss. We can’t find any discouraging remarks at all, and comments around the web indicate people are seeing great results.

The makers of Burn HD are so excited about their product they’re offering a 2-Week Sample, which is very reassuring.

Learn More About Burn HD »
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What are the ingredients in Dexedrine?

Dextroamphetamine sulfate is the main ingredient in Dexedrine. Other ingredients include but are not limited to artificial coloring, silicon dioxide, and sugar.

What are the side effects of Dexedrine?

Side effects include but are not limited to;

How do I know if Dexedrine is right for me?

Choosing the right product is the #1 question asked by DietSpotlight readers. We recommend trying any product before buying it and know that finding a product with a sample offer is near impossible - so we created our own product, Burn HD, with scientifically backed ingredients.

Click here to get your sample of our powerful fat burner today.

Does Dexedrine work?

Not all controlled substances work for every person. That being said, studies done at the University of Wisconsin-Madison proves that Dexedrine affects the prefrontal cortex in the brain.

What is the price of Dexedrine?

$54.00 to $117.00

Where can I buy Dexedrine?

At pharmacies with an accompanying prescription.

How should I take Dexedrine?

Always read the medication information that comes with your prescription. If taking the capsule or pill form, take with or without food, one to three times daily. Take in four to six-hour intervals if prescribed more than three pills daily. Take at the same time every day. Avoid taking at bedtime. When using the liquid form of, use the enclosed measuring spoon. Don’t stop taking the medicine abruptly, you will experience withdrawal.

How do I contact Dexedrine customer service?

The manufacturer of Dexedrine is, Impax Laboratories, Inc. The customer service number is (732) 595-4600.

Can I return Dexedrine?

No, the law dictates that prescriptions may not be returned.

What are the most common complaints about Dexedrine?

Too many extreme side effects and the medicine not helping adequately.


Previous Dexedrine Review (Updated December 8, 2008):

What You Should Know

Dexedrine is one of the most popular brand names for the drug dextroamphetamine. Dextroamphetamine is a central nervous system stimulant that increases wakefulness and concentration. It is one of the drugs currently used in a popular medication for ADHD.

Dexedrine was developed by Smith Kline in 1937 and has since been used to treat depression, attention disorders, narcolepsy, depression, and obesity. Dexedrine is currently being used on an experimental basis for physiotherapy patients to improve their stamina, reducing fatigue in cancer patients undergoing chemotherapy and radiation and as an anti-depressant for HIV and AIDS patients.

Because of its habit-forming properties and its potential for abuse, Dexadrine was added to the controlled substances list in 1970. Withdrawal from the drug can be accompanied by fatigue, anxiety, depression, and even psychosis. Dexedrine can only be legally obtained through a physician's prescription. Illegal traffic in Dexedrine and other amphetamines can bring huge fines and jail terms. Because of Dexedrine's potential for adverse reaction it is one of the most regulated drugs in the country.


Not really available.

Product Features

Dexedrine is often prescribed in obesity cases where weight loss is not occurring through other means and continued obesity is dangerous. It should not be prescribed lightly as a weight loss aid and should never be purchased through non-physician channels.

Dexedrine can assist in weight loss by stimulating the central nervous and suppressing appetite. Stimulants also tend to increase activity which also helps to burn calories. The correct dosage of Dexedrine may need to be fine-tuned as too much may cause anxiety, euphoria, and increased aggression in some people. Although Dexedrine can be helpful in extreme cases of obesity, it is not a "magic pill" for weight loss.


  • May be able to increase activity and concentration levels
  • May suppress appetite in extreme cases of obesity.


  • It is a habit-forming drug.
  • May cause a slew of adverse side-effects.
  • Should not to be used for regular weight loss.


Dexedrine has been a useful multi-purpose drug for over 70 years. Dexedrine is an important tool that physicians can use to combat dangerous cases of obesity but it is certainly not a drug to be taken lightly. For those looking to lose weight and burn fat, there are many over-the-counter weight loss aids that contain non-prescription stimulants (such as caffeine and green tea extract) that have been clinically-proven to increase metabolism and burn fat. Those who are morbidly obese should consult with a physician before starting any weight loss regimen. A physician can assess whether he or she feels that Dexedrine may help on a case-by-case basis.

Summer Banks Dietspotlight Author
About the Author:

Summer Banks, Director of Content at Dietspotlight, has researched over 5000 weight-loss programs, pills, shakes and diet plans. Previously, she managed 15 supplement brands, worked with doctors specializing in weight loss and completed coursework in nutrition at Stanford University. full bio.

18 Dexedrine Reviews

  • Would dexedrine help with hypersommina

    Would dexedrine help with hypersommina?

    • Maribel (Editor)

      Hello Karen, because of possible interactions with Hypersommina, please make sure to consult with your physician before taking this product.

  • Is it safe for good health?

    Is Dexedrine safe to take for weight loss if you are in good health and take it like your supposed to?

    • Maribel (Editor)

      Hello Tammy. There are positive and negative feedback out there. Some have mentioned experiencing adverse reactions, while others have said it to reduce appetite and keep them alert. So, the truth is, everyone reacts differently. Using it as instructed and it in good health definitely helps. Another product to explore is Dietspotlight Burn. It’s known to be safe and is backed by clinical research and happy customers.

  •  It works for me.
    Matt (Verified User)

    I have been on this since I was 5. I am 31 and it still kills my appetite although I use it for hyperactivity. I take 60-90 mg per day though and I am thinner… when I move, doctors make me go through the adderall, vyvanse, ritalin nightmare before going back on dexedrine again. I take the immediate release, the long acting made me not eat and go nuts… they are marketing it for ADHD under zenzedi and I had hopes it came in 2.5 mg to 30 mg like adderall. It is a pain to have to get 270 pills every month and I tried the desoxyn (rx meth) route as a teen and only for 2 months. it had to be ordered but the rx was sent out for that amount and my mom used to get the third degree and everything and it used to come in 15 mg long acting and now it is only 5 mg ir ones… plus it is more neurotoxic so I am set with the dextroamphetamine… it has never let me down. Adderall made me feel like god, I was hooked on that, Ritalin was worthless, focalin made me demented… even with ADHD, these meds are serious business… I skip one dose and I act like a hyper, obnoxious 15 year old.

  • Is this safe for my daughter?

    My 5yr old was just prescribed dexatrine for ADHD.She’s very active and has a diffucult time in school.She’s only 47lbs and Ive heard so much abt this med suppressing the appetite.She was given 5mg per day.Should I be worried?

  • information
    lajeana durham

    I was told from a pharmacist gloskosmith and kline sold patent to dexadrine and company tols me the drug could be purchased for approximately at 500.00 the illinois pharmacy stated it is sold to amedra and sales for 2000.00 is the information correct haha

  • badr abbad alotiby

    I want buy dexedrine drug, can you send to me?

    • Maribel (Editor)

      Hi! Sorry that we cannot send you…we’re not associated with the company. However, we do know there’s a 15-day sample from Dietspotlight Burn. It’s known to boost your metabolism and energy, plus helps burn fat.

  •  Loved the product but little side effect.
    carol (Verified User)

    i have been taking 15mg of dexedrine for weight loss for two weeks now. I noticed results the first day, less cravings and more energy. The last three days I have had sore eyes and tightness in my face and a plugged feeling in my ears. Had a hard time sleeping last night. I am concerend of this side affect, Carol

    • Christina

      Sounds like you should talk to you doctor Carol!! I’ve been taking Dexedrine for about a year for ADHD and I have not felt anything like that. AND I am on 60mg per day!

  • I want to know something
    kathy foley (Verified User)

    I have just started taking Dexadrine for ADD and find that I am constantly trying to take a deep breath and yawning, and not always quite getting the deep breath. Is this a normal reaction, and if so, will it eventually go away?

    • Anita

      Try taking nuvigil 100mgs, every eight hours apart. The self-samed as the dextrine. My Christian friend. Your automately see improving result expeacially on cognitive conscience awareness. I have nomore cluttered thoughts nor a messes home.I write like a scholar should write along with my ominiscience memory

    • erin

      sounds like classic anxiety. this used to happen to me all the time when i was younger… always had some problems with anxiety. Dexedrine can increase anxiety… I recently began taking it and this side effect started happening again but i immediately recognized it as anxiety. I was in exams so it made sense. your dose might be too high or you’re just stressed.

      • Anonymous

        Actually you are experiencing metabolic acidosis. Your lungs are actually trying to pull in more oxygen to offset the acidic effect that the amphetamine is having on your stomach. Try taking an antacid when you experience these symptoms.

        • Anonymous

          I wouldn’t advise taking an antacid, as amphetamines absorb better in a basic stomach. The antacid would make your stomach more basic, and the same dose that causes minor anxiety normall could make you full-on *speed-wired* when taken with antacids.

          I speak from personal experience (what an afternoon THAT was), as well as a lot of anecdotal and some scientific (PubMed, etc.) reports.

          Acidosis is highly unlikely, because Dexedrine (dextroamphetamine sulfate) is taken at maximum in 30 mg doses, and 30 mg of a sulphate salt is not significant enough to really throw off your stomach’s very adjustable pH balance.

          As far as anxiety goes, I found that if my heart rate broke 90 bpm (my normal healthy rate is 80 bpm; apparently I have a pre-Whoville-event-Grinch-sized heart) I’d get super nervous about it, and obsessively check it. Ruined my day! I’d worry about whether I’d be taken off the medication, I’d worry about whether it was hurting my cardiovascular health, etc. I’d also end up taking a lot of deep breaths as my dose was wearing off, but they’d actually be pretty satisfying. Only downside was it annoyed my girlfriend, whose head was resting on my chest at the time.

          It’s probably not in your head – there are sound physiological reasons for these side-effects – but you can control it somewhat with your mighty brain power. Just sit back with a cool, suger-and-caffeine-free beverage, play some of your favourite smooth music, and chill *all the way* out.

          And for heaven’s sake, tell your doctor first chance you get. The Internet is not your friend. I could easily be lying right now. I’m not lying, but I could be. And it’s hard to decipher liars via black text on a white background.

  • Could dex be the problem?
    Buddy Love

    I am tking dexz 5 miligrams 4 times a day.I am a performer and have had 2 major concerts since taking the medicine and have had an incredible attack of what I think is anxiety.There are voices in my head that seem to want to make me mess up the performance so I spend most of the time reasoning with this voice in my head. But i feel it coming on about 2/3 hours prior to the concert and during the concert it is the most uncomfortable unpleasant experience I have ever had in my life. I have not had performance problems in the past.Could dex be the problem? I am taking it for depression along with wellbutrin.

    • Leslie

      I am not a doctor, but if you are hearing voices, you definitely need to speak to your doctor about that and all the other side effects to in your post.

      I needed adderall when I was younger and switched over to Dex a few years ago and have never had side effects that harsh. Also, I knew a ton of people in college taking ADD meds and never heard anyone complain of voices, so hopefully if you haven’t already, you will talk to your doctor to make sure you are comfortable and safe.

      Are you seeing a psychiatrist or a General Practioner? I am only asking because I noticed you are also on Welbutrin, which in addition to helping with depression/amxiety, also helps with focus like an ADD med. I was prescrible Welbutrin in college and had a horrible experience; I felt like I was out of my mind, anxious, depressed, catatonic yet paranoid (most side effect I had never experienced before.) My doctor prescribed The Welbutrin to try to get a one in all type medicine to help with my ADHD, anxiety and depression in one. BAD MISTAKE!

      I know everyone is different, but for me, Welbutrin was hell on earth. I have never felt so low.

      Immediately my doctor pulled me off Welbutrin and switched me over to the following:
      1) Celexa 20mg for anxiety & depression(switched to Lexapro in 2005, but no complatins about celexa)
      2) Adderoll 20mg 2/day for ADHD (Last year switched over to Dex, but that is another conversation – Good decision for me though.)
      3) Xanax .5mg 1-2 tablets as needed for panic attacks (this is also very good if you are having a hard time in the evening winding down to prepare for bed…you know feeling like you just drank 10 cappuccinos and your mind is running, but your body is too tired physically and mentally to do anything productive at this point.)
      4) Ambien 10mg 1-2 tablets as needed at bedtime for insomnia (I find this extremely useful, especially if the ADHD/ADD meds are still in your system and you have an early morning.

      In summary, maybe ask your doctor why he is prescribing Dex on top of Welbutrin. I have had no problems with Adderoll or Dex, but I have with Welbutrin. Maybe you could ask him to talk to you about Celexa or Lexapro for the depression/anxiety, Adderoll vs Dex ( My doc & I prefer Dex becasue it is shorter acting and you have more control of your dosing schedule during the day, but Adderoll is just a combination of 4 amphetamine salts including dex, so the different salts wear off at tapered times in hope to reduce as much crash effect as possible. The half life of adderoll is also longer, which most people like, but I am partial to dex because it is just pure dextroamphetamine that comes into your system quickly and leaves quickly giving you more control to decide when you want it to wear off… ie: leaving work early to join a family function or knowing in advance you will be at work not 10 hours today, but you need to finalize a project and you will be working until 10pm at the office with your colleagues. Adderoll would last longer than dex, so I wouldn’t have the option of taking another in the late afternoon so I could be my most productive with the team that night.

      Hope I didn’t go off tangent too much! And I hope this kinda helps!