Updated: 05/23/2017
By Luis Miguel Apr 18, 2017

You’re at the point where you want to shed that extra weight without fighting through another failed attempt. We took an in-depth look at Duromine side effects, ingredients and clinical research. We read through hundreds of forum posts, online discussions, and comments. Then, we summarized to give you the bottom line.

EDITOR'S TIP: Substitute Duromine with a safe and proven fat burner such as Leptigen (reliable shipping to Australia & New Zealand) for better results.

What is Duromine?

Firstly, Duromine is a branded prescription appetite suppressant that contains phentermine,[1] which is only available while under a doctor’s care. You take the medication once daily, or as directed by your physician. It only works to help you eat less,[2] it doesn’t boost metabolism or increase calorie burn. It is portable, so there’s no issue taking it on the go.

Valeant Pharmaceuticals is a division of iNova Pharmaceuticals.The company behind Duromine was established in 2001. You can purchase it in Australian pharmacies and online with a prescription. We like the fact that the business has been around for quite a while and there are positive reviews of the medication, but read on…

Duromine Side Effects – “Watch Out!”

Our first concern deals with Duromine side effects, [3] something all dieters should consider. “This is something of an issue with prescription medications,” says our Research Editor. “You have to weigh the pros against the cons to see if the outcome is worth a try. Some of the adverse reactions can be harsh, and you’re not getting that kick to metabolism available from some weight-loss supplements.”

  • A dieter reports, “I just started taking Duromine…and my body is shaking and I have a headache.”
  • “I have been taking [Duromine] tablets for three days now, I woke up [last] night and could not stop vomiting,” says another user.
  • “The side effects [are too] severe and I can’t cope with feeling depressed. Headaches, pressure on my chest, muscle cramps…nausea, insomnia, loss of concentration. It’s not worth it,” one dieter claims.

Price – “A Serious Concern”

We found dieters in forums complaining about the price of Duromine. You can expect to pay a minimum of $100 a month for your prescription. That cost is in addition to the initial doctor’s visit expense and subsequent appointments. Plus, you don’t have access to a guarantee or return policy like you would with a diet supplement from a trusted company.

  • “I just got Duromine…today and it costs a fortune,” one dieter reports.
  • Another buyer claims, “Duromine is EXPENSIVE – I nearly fell off my seat when I found out it was around $3 per pill.”

When there are issues with a diet pill, our research shows a hiccup in long-term success. If the dieter does suffer side effects with Duromine, [4] or if the price is too high, that could be a problem.

The Science – “Any Clinical Support?”

The Duromine ingredient has been clinically tested and proven to reduce appetite. That’s what you’d expect from a prescription medication. But, there is also proof that side effects [5] are a serious consideration. We also believe that appetite suppression is only one part of the equation. You need to spark metabolism, so you lose fat – plain and straightforward.

Does Duromine Work?

Are we talking to our doctor right now about a Duromine prescription? We like that some dieters lose weight while taking the drug and the company has been in business for quite some time. But, with the potential side effects and high cost, we don’t feel comfortable recommending the product.

For dieters who’d like to melt away the pounds, DietSpotlight suggests a supplement that comes at a price that doesn’t break the wallet. It’s always good if the ingredients are tested and customers consistently report some amazing results.

Among the best products we’ve seen this year is a product called Dietspotlight Burn. There are just four ingredients, all clinically-tested and shown to help people with metabolism, fat loss and hunger. We’ve heard from tons of users who’ve achieved lasting weight-loss and noticed amazing results.

Plus, there’s a great confidence behind the formula, so the company is offering a Special Trial Offer, which is a good sign.

Duromine is a brand name for phentermine. The product is not available in the United States. You can find it in countries like Australia and New Zealand.

Duromine Ingredients and Supplement Facts

Serving Size: Varies
Serving Per Container: Varies
Amount per Serving % DV
Phentermine * *

Other Ingredients: None

We really dug deep and took a close look at the Duromine ingredients in order to provide you with the important details and facts you need.


Also known as brand names like Adipex, Qsymia, Suprenza, Oby-Cap and Zantryl, Phentermine is a prescription weight-loss medication. This drug is similar to an amphetamine, and it is generally prescribed along with diet and exercise.

What is it Supposed to Do?

Phentermine is supposed to help suppress your appetite. This way you eat less food, which means fewer calories. Over time, this can help you lose weight.

Clinical Research

There is some documented research that supports this drug for weight-loss. For instance, WebMD states, “Phentermine is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. It may work by decreasing your appetite, increasing the amount of energy used by your body, or by affecting certain parts of the brain. This medication is an appetite suppressant and belongs to a class of drugs called sympathomimetic amines.” [1]

Liquid Paraffin

Liquid paraffin is basically a highly-refined mineral oil. It is commonly used in pharmaceuticals, cosmetics, dietary supplements, and even for machine lubrication.

What is it Supposed to Do?

Often liquid paraffin is used to treat constipation or intestinal obstructions. Since it is not easily absorbed by the body, this substance simply passes through the digestive tract.

Clinical Research

There is no correlation between paraffin and fat loss or appetite suppression. On the other hand, this component can be used as a laxative or stool softener. According to Pediatrics International, “Liquid paraffin is more effective in the treatment of children with constipation. Patients treated with liquid paraffin responded more rapidly than patients responding to lactulose and showed fewer side-effects.” [2]

Magnesium Stearate

Magnesium stearate is a common chemical compound that is often used in cosmetics, pharmaceuticals, supplements, baby formulas, and hard candies. It works as a lubricant and binding agent.

What is it Supposed to Do?

Magnesium stearate is often used in dietary supplements and pharmaceuticals as a lubricant or anti-adherent. It helps prevent other ingredients or substances from sticking to the manufacturing equipment.

Clinical Research

There is no direct link between magnesium stearate and weight-loss. However, research has shown that this substance functions well as an inactive ingredient in pharmaceuticals and dietary supplements. It essentially helps prevent active ingredients from sticking to machinery, so they can flow smoothly.

These ingredients are clinically proven, but there are also proven risks of side effects that can affect overall health and wellness. Science is out there for natural supplements too. Read more about Dietspotlight Burn to see what we’re talking about.

Duromine Side Effects:

In today’s weight-loss society, it’s easy to think the natural solution is one without side effects. Each formula is different, and in turn, could have a different affect on each individual user. While Duromine side effects are fairly uncommon, it doesn’t mean they don’t exist for some.


The shakes are uncontrollable trembling, shivering, or jittering. Effects are most common in withdrawals; feeling as if you can’t relax or sit still for any given amount of time. Shakes are sometimes referred to as tremors, which are also effects of the nervous system and could be caused by a more serious medical condition.

What causes the shakes?

Shakes are typically caused by an ingested substance like nicotine, alcohol, caffeine, or toxins. These elements can cause neurological issues, which could cause shaking. These symptoms are common in the hands and legs primarily.


Insomnia is the inability to sleep or stay asleep when given the time to rest. Insomnia can cause you to feel dissatisfied with your nightly sleep, feeling weak, drowsy, and unable to concentrate. There are two types of insomnia, acute and chronic.

What causes insomnia?

Medical illness, pain, anxiety, or other substances such as tobacco or recreational drugs can cause insomnia. [1] Over activity, travel, and depression can also be causes for insomnia, preventing the body from getting the rest it needs.

Dry Mouth

Dry Mouth is a sticky and dry feeling in your mouth, tongue and throat. Dry mouth can cause sores, cracked lips, bad breath, and increased risk of tooth decay.

What causes dry mouth?

Dry mouth is caused by salivary glands in the mouth not performing properly. Stress, nervousness, some medications, and autoimmune disorders can cause dry mouth, as well as basic aging.


Diarrhea is a common digestive disorder in which watery or loose feces are expelled from the bowels at an irregularly frequent rate. This effect can cause bloating, nausea, and stomach pains as well as increased sweating and cramping of the abdomen.

What causes diarrhea?

All diarrhea is either infectious or osmotic. [2] Infectious can be bacteria or virus-related, disrupting the process of gastrointestinal absorption. Parasites from raw food can be a factor, as well as improper cleansing of the hands.

Duromine side effects are fairly rare, but there have been some reports of diarrhea, dry mouth, and insomnia, among others. In order to protect yourself from any unforeseen negative issues, it’s always best to consult a physician before taking any supplement. This especially goes for people who are pregnant or nursing, under the age of 18, have a pre-existing medical condition, or are taking any prescription medications.

Without a doubt, with Duromine you have the chance for clinically proven side effects. That’s a risk you take with prescription medications of any kind. Before jumping in to something like this, you may want to take a look at Dietspotlight Burn.

Duromine Questions & Answers:

We boiled down hundreds of user comments about Duromine into this helpful FAQ.

What are the side effects of Duromine?

Duromine side effects reported by iNova Pharmaceuticals, include increased heart rate, sleeplessness, restlessness, dizziness, nausea, diarrhea, constipation and stomach cramps. [1]

What are the ingredients in Duromine?

Duromine ingredients include phentermine, lactose, paraffin, magnesium stearate, titanium dioxide and iron oxide.

Does Duromine work?

Yes, Duromine works, considering the product is a prescription medication. But, something to think about is the possible occurrence of side effects.

How much does Duromine cost?

Duromine costs about $100 for a 30-day supply. You’ll need to check with your local pharmacy for exact pricing details.

How should I take Duromine?

You should take Duromine according to the instructions provided by your physician. The company behind Duromine states to not use the medication late in the day to avoid sleeplessness.

Can I take Duromine if I have a health condition?

Women who are pregnant or nursing, those with health conditions of any kind, people under 18 years of age or anyone taking prescription medication should consult with a licensed healthcare professional prior to using any type of medication, including Duromine. [2]

What do users like about Duromine?

Some users liked the boost in energy while taking Duromine.

What do users NOT like about Duromine?

We found some users didn’t like the Duromine side effects or the cost.

How do I contact the Duromine customer service department?

You can contact the Duromine customer service department by sending messages through the feedback form on the official website, mailing correspondence to iNova Pharmaceuticals Level 10 12 Help St. Chatswood NSW 2067 Australia, emailing customerservice@inovapharma.com or by calling an agent at +61 2 8918 6322.

Can I contact Duromine through social media?

Yes, you can contact Duromine through Facebook and Twitter.

When is the best time to take Duromine?

The best time to take Duromine should be determined by the physician who prescribed the medication, although the company that makes the supplement suggests using in the morning.

What are the strengths of Duromine?

Duromine is available in three strengths, 15mg, 30mg or 45mg.

Does Duromine come with a guarantee?

Duromine doesn’t come with a guarantee.
We have heard from thousands of dieters over the years that want a solution to weight-loss without the expense of medications like Duromine. There is science out there that supports Dietspotlight Burn, so take a look.

Previous Duromine Review (Updated July 3, 2014):

What You Should Know - Duromine Facts

Duromine is the popular name-brand formula for controversial diet supplement Phentermine, usually prescribed to morbidly obese patients. Duromine is usually only available with a doctor's prescription, although it can be purchased over the Internet without one. Duromine's main function? To suppress appetite, which is its only purpose. Duromine is one of the few diet supplements the FDA recognizes as a suitable diet aid for morbidly obese patients, but this also means that it must be taken under direct doctor supervision to avoid severe or fatal consequences. Duromine, although proven scientifically effective, also comes with numerous side effects, which is why it is highly recommended Duromine should be taken under doctor supervision. Currently Duromine is only available in Australia and its surrounding countries. Duromine is available in three strengths -- 15mg, 30mg, and 40mg. A doctor will recommend the appropriate strength depending on your health history. Duromine is also free of gluten and preservatives, although it contains gelatin. Because it is a FDA-approved drug, money-back guarantees are served on a case-by-case basis. A doctor may allow you to try free samples if you request it and meet the requirements. Unlike other diet supplements, Duromine has strict requirements and is only recommended for short-term weight loss. Usage should not exceed 12 weeks.


Phentermine, Titanium Dioxide, Magnesium, Carbon Black, Lactosevliquid Paraffin, Gelatin, Brilliant Blue FCF, Iron Oxide Yellow. Duromine's 30mg capsules contain Brilliant Blue FCF and Iron Oxide Yellow. Their 40mg capsules contain Erythrosine and Sunset Yellow FCF.

Product Features

Duromine is a prescription-only supplement, only available to patients with a BMI Index over 27 and a history of obesity-related illnesses, such as high blood pressure and diabetes. Phentermine, its main ingredient, alters brain chemistry and helps suppress appetite. These claims are medically backed by numerous groups and organizations, including the FDA. Combined with diet and exercise, Duromine claims that it helps morbidly obese patients lower their BMI Index, although the amount of weight loss varies from person to person. Numerous studies conducted on Duromine back up these results. Unfortunately, Phentermine is highly addictive. Duromine only recommends taking the product for up to 12 weeks. Some patients are ineligible for Duromine if they have a history of addiction or prescription abuse. Phentermine also has numerous side effects, including impotence and diarrhea.

Duromine Advantages

  • Duromine is FDA approved for quality, truthfulness, and dependability.
  • It is clinically proven to suppress appetite.
  • Duromine is gluten and preservative free.

Duromine Disadvantages

  • It is only legally prescribed to patients meeting strict criteria.
  • There are numerous side effects, some of which are fatal or severe.
  • It is only intended for short weight loss - taking it too long might result in addiction.
  • Currently, it is only available through manufacturers in Australia and its surrounding countries.


Although Duromine is a FDA approved drug, it is not completely safe. Numerous side effects should discourage casual dieters, as should the product's strict guidelines. Duromine is only an option for morbidly obese people with obesity-related illnesses and is not recommended for other body types. A doctor can only recommend and approve this drug for use, and it is very dangerous - and unethical - to take Duromine without a prescription. It does appear to be a viable solution for obese patients who need a short term fix, however.

Duromine Scientific Abstracts:


The US FDA (Food and Drug Administration) has approved a fixed-dose (mid-2012) mixture of topiramate extended-release and phentermine immediate release for the treatment of overweight or obese human patients. The new drug has displayed strong weight-loss capabilities in comparison to placebo for a time frame of up to 2 years. [1]

Phentermine has been approved for the short-term treatment of overweight and obese humans in partnership with lifestyle modifications. Topiramate, which has been approved for treatment of epilepsy and prevention of migraines, also helps with weight-loss. Cardiovascular data linked to long-term use of topiramate extended-release and phentermine indicate that the combination may be an effective, as well as safe, choice in decreasing weight in obese patients at low-to-intermediate cardiovascular risk. [2]

There was an 84% completion rate in the study. During week #108, controlled-release phentermine and topiramate (PHEN/TPM CR) was linked with substantial and sustained weight-loss (intent-to-treat with last observation carried forward; P < 0.0001 compared to those who consumed placebo). Least-squares MP (mean percentage) shifts from baseline in body weight were –1.8%, –9.3%, and –10.5% for the placebo group, 7.5/46, and 15/92. There had been a substantial weight-loss comparison in PHEN/TPM CR–treated participants compared to placebo (P < 0.001). In conclusion, the controlled-release phentermine and topiramate in conjunction with lifestyle modification could offer an efficient and well-tolerated alternative for sustained treatment of obesity complicated by cardiometabolic disease. [3]

Liquid Paraffin

Liquid paraffin and lactulose were administered to 40 children volunteers with chronic functional constipation. There were improvements in stool consistency and frequency during the first four weeks of trials. Frequency was significantly higher in liquid (P < 0.01 and P < 0.05, respectively) than the paraffin group. There was a substantial increase in some stool per week with liquid paraffin for the duration of the last four weeks (P < 0.05). The compliance rates had averaged 95% in those who ingested the liquid paraffin and 90% in those who took lactulose during the four-week study, and 90% for liquid paraffin and 60% in the lactulose group for the final four weeks (chi(2) = 4.8, SD = 1, P = 0.02. It was concluded that liquid paraffin is more efficient regarding the treatment of children who suffer from constipation. The effects were more rapid in those who took the liquid paraffin than the lactulose and showed fewer side effects as well. [4]

Learn More About Dietspotlight Burn »
Dietspotlight Author
About the Author:

Luis Miguel is a dedicated health writer whose mission is to help people live stronger, happier lives. At Diet Spotlight, he gets the scoop on the latest weight loss supplements to make it easier for readers to decide which ones are worth their time and money. Luis currently lives in South Florida with his wife and children. full bio

Rating: 3.7. From 479 votes.
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User Comments

982 Comments on "Duromine Review"

Gideon Boakye

Please should i keep on taking the medicine when it get finished or i can stop when it gets finish and continue with an exercise?

Victoria (Editor)

Hi Gideon! For detailed product and usage instructions, please refer to the Duromine official website for more information.


I would like to try it – what do I have to do to qualify? Do you deliver in South Africa?


You do get it in south Africa

Victoria (Editor)

Hi! For more information on where to purchase this product, please refer to the Duromine official website.


Kindly advise should i take Duromine morning before or after breakfast ?


I take it at 6am when I wake up.


I love them…..They really do wonders for me….The only side effect that I get with Duromine is sleeplessness, and this is happens only during my first week of taking them..Otherwise I don’t get any other side effect..I used them 4 years ago when I was turning 40 and losteoporosis around 10kg in 4 months…I am a very active person..I am a spinning and aerobics fanatic .So they give me a lot of energy.So i use them in conjunction with gym…..They help me eat less and only healthy food….With Duromine , i never experience craving for wrong food like chocolates and fatty or sugarry things ….I maintained that sexy weight until this year.I am now 44 years old and have regained that weight …..I have just started using Duromine again 4 days ago…..I have a prescription for 3 months, so I hope I will be slimmer and sexy by December…..then will stop them and maintain my weight.

Victoria (Editor)

Hi Karen! For detailed product and usage instructions, please refer to the Duromine official website for more information.

Ms. M

I use to use it a couple of years ago – Where can I buy them – Nothing I’ve used worked as good I’ve been trying to get some for quite a while – I use to get them from a friend who obviously never gave me her connect and her and I are no longer friends – Please advise if you still have some – Thanks so much

You need a prescription to purchase Duromine. You can opt for a product that doesn’t require a prescription and is clinically shown to help spark metabolism for weight-loss. We like Dietspotlight Burn.


Can u use it when breastfeeding

Stephen (Editor)

Hi Zara! Because of possible interactions, please make sure to consult with your physician before taking this product.


Hi everyone, are there any issues related to drinking alcohol while on Duromine? I want to start taking it tomorrow, but i have my birthday and work christmas party coming up soon so just want to know if it will be ok to have a few drinks on those days or if i should rather wait until after they are done


Hi Michelle, have you talk to your doctor if alcohol is ohk to drink while you’re on the tablets?


what ever you do , don’t drink on them . i made that mistake when i took then a few years and after 2 shots i was in hospital and i’m a heavy weight drinker

Victoria (Editor)

Hi! Because of possible interactions, please make sure to consult with your physician before taking this product with alcohol.


I used duromine 30g about 3years ago I had very perfect results than even what i expected but recently I have gained too much weight again and I just want to know if I can take it again. Thank you and hope to hear from you

Victoria (Editor)

Hi! Please make sure to consult with your physician before starting a weight-loss program or product.


Can I use Duromine whilst on a cronic medication, e.g Epilim – controlling epilepsy?

Candace (Editor)

Only your doctor could approve of your use of multiple medications with Duromine.


Have been on duromine for 2 months and lost 14kg. It stopped me from eating chocolate, I ended up eating yoghurt instead of sweet snacks. You HAVE to drink lots of water all day. One some days I ate an apple and a few walnuts. On other days, all I could eat was a small yoghurt. A side effect could be constipation, so I then introduced high fibre bran every morning immediately after taking the duromine. My energy levels were amazing, I could work all day and my concentration was enhanced. However, I did feel drops in energy during the day (which seemed to normal for me).


Sounds very nice. Would like to try it. Where can i buy it?

Stephen (Editor)

Hey, Estelle. Duromine is a prescription drug and cannot be purchased over the counter.


Hi so I,ve looked online and see theres sites that sell duromine would you recommend purchasing this.

Devon (Editor)

We don’t recommend purchasing it without a trusted doctor’s prescription. Some sites, we found during our research, promise they’ll send Duromine only for customers to later discover a knock-off or altogether different product shipped to them.


I have an underactive thyroid…..duromine wont work that well for me..will it?


I “played” with it and umine during my I’ll spent youth. Stupid. I don’t recommend it at all for under active thyroid. I too have this. It has taken years to get the dosage right but levothyroxene is finally working. I put on close to 20kgs and kept it on for good 10 years. It happened really fast too I also lost it really fast once correct dosage was found. This has been the worst part as now I am this wrinkly mess so I suggest exercise, even just walking regularly. I feel for you as it’s one of those things people can see,like a broken arm, so you get very little support. Weight gain isn’t the only thing with under active thyroid either. Hang in there chickie tho cos there is light at the end of the tunnel

Your Name

I have an under active thyroid., menopause. I have gained 30kg. I have been taking Duromine for 2 weeks and have lost 6kg. I have more energy and feel great. I take it at 6:30am and sleep well. I hope this helps.. I do have a dry mouth some days, I drink more water and I need to urinate a lot more. Tell us your thoughts about Duromine.

Stephen (Editor)

Sally, your doctor will go over your options with you once you ask for the prescription. Only (s)he will be able to tell you accurately.

Your Name

Normally people with more weight to loose looses faster that someone who is not that overweight. Is that the same with Duromine or will I see fast results?

Cameron (Editor)

Hello. All users are different and can experience different weight-loss results, but exercise in conjunction with a healthy diet and supplements have shown to help with weight-loss.

your name

i want to try it but i am scared

Victoria (Editor)

Hi! Please make sure to consult with your physician before starting a new weight-loss program or product.

Mary grace

How Can I buy duromine

Cameron (Editor)

It must be prescribed by your doctor.


Starting day one tomorrow, thanks this post really helped me.


I am about to start my duromine experience tomorrow, what time is best to start taking it in the morning??? Thanks, any tips appreciated to get best results, water work out is already happening ?

Victoria (Editor)

Hi! For detailed product and usage instructions, please refer to the Duromine official website for more information.


I take mine at 4am every morning and go back to sleep. When I wake up in the morning at 7am I am ready to go for the day and then its worn off by bed time!


I just started using Duromine today,i have read all the side effects Im worried about the heart beating fast because I attent gym wouldnt it be contradictory?

Victoria (Editor)

Hello Andy! All users are different and can experience different side effects; please make sure to consult with your physician before taking this product.


I’m 40 weight 110 I want to lose weight badly I think duromine will work for me

Jané Stapelberg

Goodday, I would like to find out if a child of 14 years can take Duromine? Will it be safe with all the side effects?


Just picked up my pack from the chemist. The printout that was given to me by them stated “Do not give this medicine to a child under the age of 12 years” i would take said child to the doctor and talk to them about the situation …. maybe there is a better one suited for children.

Cameron (Editor)

Hi Jané, these products are intended for adults 18 or older. Please consult with your physician.


I’m 15 years old and want to take duromine but scared and nervous I don’t know if I should use it I’ve tried to lose weight and do a diet but it just won’t work. I am 85kg and hoping to lose weight. My mum got duromine 40mg but don’t know is if it’s suitable. Help

Victoria (Editor)

Hi Angella! Please make sure to consult with your physician before starting a new weight-loss program or product.


Does duromine go by a persons weight or their diet? Can you overdose on taking a higher mg but staying within the recommended intake per day?

Stephen (Editor)

Your doctor will assess your need for it when you ask for a prescription (though commonly prescribed to those suffering from obesity). You, too, must never exceed the recommended dosage as outlined by your doctor (either 15mg, 30mg, or 40mg).