I just read that prescription Duromine can “promote weight loss when used for a short time.”
Admittedly, a prescription weight-loss pill sounds a bit scary, so I’m asking:
How does this stuff work?
First of all, Duromine is meant to be taken by obese or significantly overweight individuals. It works as an appetite suppressant, using its active ingredient to affect specific parts of the nervous system. Its active ingredient can also cause increased energy levels.
But we’ll get to that in a bit.
Read these 5 things you HAVE to know before talking to your doctor about Duromine.
Let’s get started…
What is Duromine?
Firstly, Duromine is a prescription appetite suppressant that contains:
- Phentermine 
You take the medication once daily, or as directed by your physician. It only works to help you eat less,  it doesn’t boost metabolism or increase calorie burn. It is portable, so there’s no issue taking it on the go.
Valeant Pharmaceuticals is a division of iNova Pharmaceuticals.The company behind Duromine was established in 2001. You can purchase it in Australian pharmacies and online with a prescription.
We like the fact that the business has been around for quite a while and there are positive reviews of the medication, but read on…
Duromine Side Effects – “Watch Out!”
Our first concern deals with Duromine side effects,  something all dieters should consider. “This is something of an issue with prescription medications,” says our Research Editor. “You have to weigh the pros against the cons to see if the outcome is worth a try.”
A dieter reports, “I just started taking Duromine…and my body is shaking and I have a headache.”
“I have been taking [Duromine] tablets for three days now, I woke up [last] night and could not stop vomiting,” says another user.
“The side effects [are too] severe and I can’t cope with feeling depressed. Headaches, pressure on my chest, muscle cramps…nausea, insomnia, loss of concentration. It’s not worth it,” one dieter claims.
Price – “A Serious Concern”
We found dieters in forums complaining about the price of Duromine. You can expect to pay a minimum of $100 a month for your prescription. That cost is in addition to the initial doctor’s visit expense and subsequent appointments.
“I just got Duromine…today and it costs a fortune,” one dieter reports.
Another buyer claims, “Duromine is EXPENSIVE – I nearly fell off my seat when I found out it was around $3 per pill.”
When there are issues with a diet pill, our research shows a hiccup in long-term success. If the dieter does suffer side effects with Duromine,  or if the price is too high, that could be a problem.
Are Duromine Results Clinically Proven?
Claims of Duromine results are based on clinically testing, proving it can reduce appetite. That’s what you’d expect from a prescription medication. But, there is also proof that side effects  are a serious consideration.
We also believe that appetite suppression is only one part of the equation. You need to spark metabolism, so you lose fat – plain and straightforward.
The Bottom Line – Does Duromine Work?
Are we talking to our doctor right now about a Duromine prescription? We like that some dieters lose weight while taking the drug. But, with the potential side effects and high cost, we don’t feel comfortable recommending the product.
For dieters who’d like to melt away the pounds, DietSpotlight suggests a supplement that comes at a price that doesn’t break the wallet. It’s always good if the ingredients are tested and customers consistently report some amazing results.
Among the best products we’ve seen this year is a product called Dietspotlight Burn. There are just four ingredients, all clinically-tested and shown to help people with metabolism, fat loss and hunger. We’ve heard from tons of users who’ve achieved lasting weight-loss and noticed amazing results.
Plus, there’s a great confidence behind the formula, so the company is offering a Special Trial Offer, which is a good sign.
Previous Duromine Review (Updated July 3, 2014):
What You Should Know - Duromine FactsDuromine is the popular name-brand formula for controversial diet supplement Phentermine, usually prescribed to morbidly obese patients. Duromine is usually only available with a doctor's prescription, although it can be purchased over the Internet without one. Duromine's main function? To suppress appetite, which is its only purpose. Duromine is one of the few diet supplements the FDA recognizes as a suitable diet aid for morbidly obese patients, but this also means that it must be taken under direct doctor supervision to avoid severe or fatal consequences. Duromine, although proven scientifically effective, also comes with numerous side effects, which is why it is highly recommended Duromine should be taken under doctor supervision. Currently Duromine is only available in Australia and its surrounding countries. Duromine is available in three strengths -- 15mg, 30mg, and 40mg. A doctor will recommend the appropriate strength depending on your health history. Duromine is also free of gluten and preservatives, although it contains gelatin. Because it is a FDA-approved drug, money-back guarantees are served on a case-by-case basis. A doctor may allow you to try free samples if you request it and meet the requirements. Unlike other diet supplements, Duromine has strict requirements and is only recommended for short-term weight loss. Usage should not exceed 12 weeks.
IngredientsPhentermine, Titanium Dioxide, Magnesium, Carbon Black, Lactosevliquid Paraffin, Gelatin, Brilliant Blue FCF, Iron Oxide Yellow. Duromine's 30mg capsules contain Brilliant Blue FCF and Iron Oxide Yellow. Their 40mg capsules contain Erythrosine and Sunset Yellow FCF.
Product FeaturesDuromine is a prescription-only supplement, only available to patients with a BMI Index over 27 and a history of obesity-related illnesses, such as high blood pressure and diabetes. Phentermine, its main ingredient, alters brain chemistry and helps suppress appetite. These claims are medically backed by numerous groups and organizations, including the FDA. Combined with diet and exercise, Duromine claims that it helps morbidly obese patients lower their BMI Index, although the amount of weight loss varies from person to person. Numerous studies conducted on Duromine back up these results. Unfortunately, Phentermine is highly addictive. Duromine only recommends taking the product for up to 12 weeks. Some patients are ineligible for Duromine if they have a history of addiction or prescription abuse. Phentermine also has numerous side effects, including impotence and diarrhea.
- Duromine is FDA approved for quality, truthfulness, and dependability.
- It is clinically proven to suppress appetite.
- Duromine is gluten and preservative free.
- It is only legally prescribed to patients meeting strict criteria.
- There are numerous side effects, some of which are fatal or severe.
- It is only intended for short weight loss - taking it too long might result in addiction.
- Currently, it is only available through manufacturers in Australia and its surrounding countries.
ConclusionAlthough Duromine is a FDA approved drug, it is not completely safe. Numerous side effects should discourage casual dieters, as should the product's strict guidelines. Duromine is only an option for morbidly obese people with obesity-related illnesses and is not recommended for other body types. A doctor can only recommend and approve this drug for use, and it is very dangerous - and unethical - to take Duromine without a prescription. It does appear to be a viable solution for obese patients who need a short term fix, however.
Duromine is a brand name for phentermine. The product is not available in the United States. You can find it in countries like Australia and New Zealand.
Duromine Ingredients and Supplement Facts
Serving Per Container: Varies
|Amount per Serving||% DV|
Other Ingredients: None
We really dug deep and took a close look at the Duromine ingredients in order to provide you with the important details and facts you need.
Also known as brand names like Adipex, Qsymia, Suprenza, Oby-Cap and Zantryl, Phentermine is a prescription weight-loss medication. This drug is similar to an amphetamine, and it is generally prescribed along with diet and exercise.
What is it Supposed to Do?
Phentermine is supposed to help suppress your appetite. This way you eat less food, which means fewer calories. Over time, this can help you lose weight.
There is some documented research that supports this drug for weight-loss. For instance, WebMD states, “Phentermine is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight. It is used by certain overweight people, such as those who are obese or have weight-related medical problems. It may work by decreasing your appetite, increasing the amount of energy used by your body, or by affecting certain parts of the brain. This medication is an appetite suppressant and belongs to a class of drugs called sympathomimetic amines.” 
Liquid paraffin is basically a highly-refined mineral oil. It is commonly used in pharmaceuticals, cosmetics, dietary supplements, and even for machine lubrication.
What is it Supposed to Do?
Often liquid paraffin is used to treat constipation or intestinal obstructions. Since it is not easily absorbed by the body, this substance simply passes through the digestive tract.
There is no correlation between paraffin and fat loss or appetite suppression. On the other hand, this component can be used as a laxative or stool softener. According to Pediatrics International, “Liquid paraffin is more effective in the treatment of children with constipation. Patients treated with liquid paraffin responded more rapidly than patients responding to lactulose and showed fewer side-effects.” 
Magnesium stearate is a common chemical compound that is often used in cosmetics, pharmaceuticals, supplements, baby formulas, and hard candies. It works as a lubricant and binding agent.
What is it Supposed to Do?
Magnesium stearate is often used in dietary supplements and pharmaceuticals as a lubricant or anti-adherent. It helps prevent other ingredients or substances from sticking to the manufacturing equipment.
There is no direct link between magnesium stearate and weight-loss. However, research has shown that this substance functions well as an inactive ingredient in pharmaceuticals and dietary supplements. It essentially helps prevent active ingredients from sticking to machinery, so they can flow smoothly.
These ingredients are clinically proven, but there are also proven risks of side effects that can affect overall health and wellness. Science is out there for natural supplements too. Read more about Dietspotlight Burn to see what we’re talking about.
- 1. Drugs & Medications: Adipex-P (Not Listed). WebMD. October 5, 2016.
- 2. A comparative study: the efficacy of liquid paraffin and lactulose in management of chronic functional constipation. (2005). Pediatrics International. May 31, 2016.
Duromine Scientific Abstracts:
The US FDA (Food and Drug Administration) has approved a fixed-dose (mid-2012) mixture of topiramate extended-release and phentermine immediate release for the treatment of overweight or obese human patients. The new drug has displayed strong weight-loss capabilities in comparison to placebo for a time frame of up to 2 years. 
Phentermine has been approved for the short-term treatment of overweight and obese humans in partnership with lifestyle modifications. Topiramate, which has been approved for treatment of epilepsy and prevention of migraines, also helps with weight-loss. Cardiovascular data linked to long-term use of topiramate extended-release and phentermine indicate that the combination may be an effective, as well as safe, choice in decreasing weight in obese patients at low-to-intermediate cardiovascular risk. 
There was an 84% completion rate in the study. During week #108, controlled-release phentermine and topiramate (PHEN/TPM CR) was linked with substantial and sustained weight-loss (intent-to-treat with last observation carried forward; P < 0.0001 compared to those who consumed placebo). Least-squares MP (mean percentage) shifts from baseline in body weight were –1.8%, –9.3%, and –10.5% for the placebo group, 7.5/46, and 15/92. There had been a substantial weight-loss comparison in PHEN/TPM CR–treated participants compared to placebo (P < 0.001). In conclusion, the controlled-release phentermine and topiramate in conjunction with lifestyle modification could offer an efficient and well-tolerated alternative for sustained treatment of obesity complicated by cardiometabolic disease. 
Liquid paraffin and lactulose were administered to 40 children volunteers with chronic functional constipation. There were improvements in stool consistency and frequency during the first four weeks of trials. Frequency was significantly higher in liquid (P < 0.01 and P < 0.05, respectively) than the paraffin group. There was a substantial increase in some stool per week with liquid paraffin for the duration of the last four weeks (P < 0.05). The compliance rates had averaged 95% in those who ingested the liquid paraffin and 90% in those who took lactulose during the four-week study, and 90% for liquid paraffin and 60% in the lactulose group for the final four weeks (chi(2) = 4.8, SD = 1, P = 0.02. It was concluded that liquid paraffin is more efficient regarding the treatment of children who suffer from constipation. The effects were more rapid in those who took the liquid paraffin than the lactulose and showed fewer side effects as well. 
- 1. Phentermine-topiramate: First combination drug for obesity (2015). International Journal of Applied & Basic Medical Research. October 19, 2016.
- 2. Cardiovascular effects of phentermine and topiramate: a new drug combination for the treatment of obesity (2014). Journal of Hypertension. October 19, 2016.
- 3. Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study (2012). The American Journal of Clinical Nutrition. October 19, 2016.
- 4. A comparative study: the efficacy of liquid paraffin and lactulose in management of chronic functional constipation (2005). Pediatrics International: Official Journal of the Japan Pediatrics Society. October 19, 2016.