If you’ve been looking into supplements for rapid weight loss, perhaps you’ve come across a product called Fastin-XR. Fastin-XR, also known as Fastin, is a high-level weight loss intensifier made by a company called Hi-Tech Pharmaceuticals. If you’ve heard of Fastin but are overwhelmed by the amount of information available, fear not: we’ve researched the ingredients, side effects, and science behind Fastin so that you can make an informed decision before purchasing the product. As always, we will give you our thoughts as well as the bottom line on the product.
What is Fastin?
Fastin is a proprietary compound and pharmaceutical-grade weight loss formula. While Fastin-XR is available over-the-counter (OTC), the formula was designed to be administered to obese people to achieve medically-necessary weight loss.
The name Fastin of the supplement alludes to its function: Fastin can assist the user with rapid weight loss.
Fastin is made by a company called Hi-Tech Pharmaceuticals, based in Norcross, Georgia. The CEO of the company is named Jared Wheat.
Hi-Tech Pharmaceuticals manufactures some weight-loss products including CarniSlim, CoffeeTrim, and SadieTrim. They also have several other formulations in development, including Fastin for Her and a weight-loss product called Black Pirahna.
As of now, Fastin-XR appears to be Hi-Tech’s signature weight-loss formula. It distinguishes itself from the original formula by being more potent. The “XR” stands for “extended release.” Compared to their other products, Fastin-XR is probably the most-aggressive blend of stimulants, while products such as CarniSlim and CoffeeTrim are touted as “weight-loss support.”
As with many weight loss products, people tend to ask, “Does it work in the long term?” Fastin is a somewhat-unproven product, and most of the available information on Fastin would confirm this. We’ll see the latest data on Fastin in full later in the article. The million-dollar question, as with most any weight loss product is, “Is Fastin right for me?”
We’ll answer these questions and more in more detail in the paragraphs below. Keep reading for a full overview on Fastin and its potential as a weight loss product.
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Fastin-RX uses an extensive list of ingredients. As with many fat-burners and weight-loss pills, Fastin leans heavily on caffeine. Here are some of the other ingredients in Fastin-RX, along with the science behind each:
For metabolic and blood pressure regulations, Thermo-RX is commonly used. It primarily assists in blood pressure elevation. 
2. Phenylethylamine HCL
Phenylethylamine HCL helps to regulate the thyroid glands in the body. An overactive or under-active thyroid gland is never a good thing. The studies behind this one have seen mixed results. 
3. Methylsynephrine HCL
This compound is thermogenic. It rapidly elevates heart rate and metabolism. Some evidence has shown initial negative results. Further studies are necessary, especially as they may relate to the long-term benefits and effects of Methylsynephrine HCL. 
4. Theobromine Anhydrous
This assists in mental health, primarily neurological disorders. Unlike most forms of caffeine, it contains far less concentrated amounts, and the dosage or intake can be monitored much more accurately. Theobromine has also been reported to clear the mind when repeatedly taken throughout the day. To date, the results and opinions in the health community have been mixed. 
Because Fastin contains caffeine, the dosing benefits of including theobromine are somewhat mitigated.
5. 1,3-Dimethylamine HCL
The fat-burning and lipolytic potential here are unique. 3-Dimethylamine HCL is contained in many dietary supplements. 
6. Synephrine HCL
Keep two things in mind in the case of Synephrine HCL: while it has promoted weight loss and successfully achieved it in some individuals, in numerous cases, it has caused adverse side effects. 
We suggest you exercise caution before consuming products containing Synephrine HCL.
7. Yohimbine HCL
Yohimbine is often used as an erectile dysfunction prescription drug or testosterone booster but has many other uses. The positive and potentially-negative effects of Yohimbine are well-documented. 
8. N-methyl-b-phenylethylamine HCL
This ingredient primarily consists of antidepressants and stimulates beta receptor activity. It also slows down one’s heartbeat, a major concern noted among those who have used it.
Aside from the concerns over slowing down heart rate, another thing we don’t like about this compound is its potential for addiction. 
Educate yourself and consult with your doctor before taking products containing N-methyl-b-phenylethylamine HCL or any compound that has the potential to slow your heart rate or promote addiction. 
Caffeine is a staple in weight-loss and fat-loss supplements, and Fastin is no different. Fastin contains 150-200 milligrams of caffeine, depending on the formulation, and one cup of regular coffee contains about 95 mg.
Too much caffeine can, of course, be a problem, and many people tend to take in excessive amounts by not monitoring their caffeine intake closely. 
Fastin was introduced around 2010 from Hi-Tech Pharmaceuticals. The supplement is sold through the official website and established retailers. We like a few of the ingredients and that we found some positive customer comments, but read on…
What is Beta-methylphenethylamine?
The key ingredient that deserves special consideration is beta-methylphenethylamine.
Also known as BMPEA, beta-methylphenethylamine is a member of the phenethylamine family of chemicals, which also includes amphetamines and hallucinogens like mescaline. firth
According to University of California San Diego professor of chemistry Dionicio Siegel, who studies phenethylamines, this class of substances can target some brain receptors controlling energy, but also have LSD-like effects. 
There are serious health concerns regarding BMPEA. From an NBC News report:
BMPEA has never been tested in people for safety or efficacy.
BMPEA has been shown to raise blood pressure and heart rates in dogs and cats. It is classified as a doping agent by the World Anti-Doping Agency because it is closely related to amphetamine.
Hi-Tech Pharmaceuticals, a manufacturer of supplements containing BMPEA and a supplier to other supplement makers, says it has conducted a clinical trial of a supplement containing it on ten men. According to the results, the subjects’ heart rates increased by 11 beats per minute, and systolic blood pressure rose 22 points. Hi-Tech paid for that study.
We would advise extreme caution before taking any product that contains BMPEA. There is simply not enough clinical evidence that BMPEA is safe.
Fastin Nutrition Facts
Fastin comes in a 245-375 mg per tablet dose, depending on the formulation.
There are no minimum daily values for any of the ingredients in Fastin, and there are no vitamins or minerals.
Given the relatively high dose of caffeine in each Fastin pill, we think it would be wise to assess your caffeine tolerance before ingesting a tablet. The “Fastin How to Use” section includes information on how to assess your tolerance.
What Does Fastin Do?
Fastin claims to boost metabolism, and given the lengthy list of stimulants in the ingredients list, we think it probably works as a potent energy booster in many people. There is not a lot of hard data available to back this claim.
Hi-Tech Pharmaceuticals advertises Fastin as an energy booster and an appetite suppressant, and we believe that’s true in fashion. Our concern is jitters and “false energy,” as there is nothing within the formula that specifically burns fat and preserves lean muscle. For example, Yohimbine is often put into testosterone-boosting supplements and reputed as a libido booster, and but Yohimbine’s direct effect on body composition and fat loss is less well-established.
One study on the body composition and exercise performance of men’s soccer players  found the following:
The athletes (20 top-level male soccer players) were allocated to two randomly assigned trials. Subjects in the yohimbine group orally ingested tablets that contains yohimbine at a dose of 20 milligrams per day in two equal doses for 21 days. Subjects in the placebo group ingested an equal number of identical-looking pills that contained cellulose.
No subject reported any side effects from yohimbine. The results of the current study indicate that supplementation with yohimbine combined with resistance training does not significantly alter the body mass, muscle mass, or performance indicators in professional soccer players.
Based on this study, it appears Yohimbine does have an impact on fat loss. But this study was conducted on professional soccer players without account for their massive energy deficits. Professional soccer players account for a fractional portion of the population. This study is not without merit, but it was done on a statistically-tiny portion of the population.
And even if Yohimbine is an effective ingredient, given the list of ingredients with adverse side effects, we would be reluctant to give Fastin our full endorsement.
While this potent stimulant cocktail might give a sluggish metabolism a kick in the seat of the pants, anyone using Fastin or a similar formulation needs to be concerned about the considerable list of potential side effects. We cover those in detail below.
Does Fastin Work?
In our review, we have determined that like many weight-loss products, Fastin can be effective if used properly. But this assumes a number of things and ignores the fact that a significant number of users have had problems with Fastin.
It should go without saying that there is no such thing as a miracle pill that will allow you to lose body fat with no changes to your diet, exercise plan, and lifestyle. Those factors are the most important, and supplements can be viewed as a finishing touch on an otherwise sound weight-loss plan.
Reviews on Fastin have been notably mixed.
In clinical settings, when combined with controlled calorie and carbohydrate intakes, Fastin has proven to be successful in helping obese people lose substantial amounts of weight. But the effectiveness of the dietary approaches themselves also needs to be taken into account.  
How Does Fastin Work?
Fastin is otherwise known by the generic name phentermine. Phentermine is an amphetamine-like prescription medication primarily used to suppress appetite. This is the main mechanism through which people lose weight while using Fastin or phentermine, in conjunction with an intelligent weight loss program. 
Fastin also features some ingredients that may individually have fat-burning effects. As noted above, you can find studies which connect Yohimbine with fat loss. Caffeine is well-known for its metabolic and thermogenic properties.
But we suspect Fastin works on the flawed premise that “more” equates “better.” There is very little science linking the fat-burning properties of phenylethylamine and theobromine, for example. Given the lack of science, it appears that some compounds with fat-burning or thermogenic potential were simply mixed. Thus, it’s hard to determine which compounds are effective for fat loss or weight loss and which are not.
Furthermore, and this will be addressed in full below, but some of the compounds within Fastin – such as Methylsynephrine HCL – have a litany of adverse side effects. 
This is from the release by the FDA (Food and Drug Administration) on Methlsynephrine:
In recent years, FDA has identified some sports products that are marketed as dietary supplements but contain substances that don’t qualify as dietary ingredients and may pose health risks to consumers.
Methylsynephrine has joined the list of substances that are the subject of FDA warning letters to marketers of sports products.
The FDA explained further on a webpage linking to the warning letters:
“Methylsynephrine is not approved as a food additive or prior sanctioned for use in dietary supplements,” FDA stated in the warning letters. “Further, FDA’s review of this substance does not identify a basis to conclude that the substance is GRAS [generally recognized as safe] for use in food.”
The takeaway from this is to be very careful with the supplements you select. Many manufacturers try to pass off unsafe ingredients as safe to consume. We recommend that you always talk to your doctor before considering any supplement with effects this potent.
Lastly, it goes without saying that no weight loss supplement works without a smart, calorie-controlled diet plan. We like diets such as the Paleo Diet and the Ketogenic Diet, both of which encourage more natural food choices and less processed sugar.
Does Fastin Have Side Effects?
Fastin does have some reported side effects. Here are some specific concerns, broken down into key categories:
Tolerance to the anorectic effect, or almost complete loss of appetite, usually develops within a few weeks of phentermine use. When this occurs, the recommended dose should not be exceeded in an attempt to increase the effect; rather, the drug should be discontinued. 
Two commonly reported side effects of Phentermine are tachycardia (rapid heart rate) and elevated blood pressure.
Other reported side effects include regurgitant cardiac valvular disease, primary pulmonary hypertension, palpitations, precordial pain, ischemic events, angina, myocardial infarction, and even cardiac arrest and failure.
Central Nervous System
Phentermine is intended to stimulate the Central Nervous System (CNS), the perceived and actual levels of stimulation vary greatly from user to user. Some have claimed improved focus and energy, while others have reported severe jitters, trembling, and blurred vision.
Overstimulation is a common occurrence with the use of stimulant cocktails such as Fastin-XR. When an individual is said to be overstimulated, he or she has trouble focusing and completing routine tasks. Fastin’s similarity to amphetamines has led many users and clinicians to report overstimulation in both regular and extreme cases. 
In this vein, hyperreflexia is a concern. As the name implies, one’s reflexes become hyperactive. While quick reflexes are desirable, particularly in sports, a chronically-overstimulated nervous system is not desirable. Stimulant blends such as Fastin-XR can burn out motor neurons and condition a person to rely upon stimulants for normal CNS response. 
Another one of the most commonly-reported side effects of Fastin-XR is insomnia and difficulty getting to sleep.  From the Phentermine website:
Throughout the day, phentermine stimulates the brain to be more efficient and alert, increasing energy levels and concentration, but these enhanced levels of alertness can then interfere with your body’s ability to sleep, often despite feelings of tiredness. Some people believe that phentermine may inhibit the release of melatonin, the hormone which is released by the onset of darkness to bring about sleep. However, this is not thought to be the cause of insomnia from phentermine. Instead, it is more likely that the enhanced alertness which phentermine causes by stimulating the central nervous system inhibits the ability to sleep, despite the release of melatonin.
Lastly, Tachyphylaxis is the continued or repeated exposure to a drug that may lead to a weak pharmacological response. This is particularly true in drugs such as phentermine, which targets the CNS. 
Phentermine has been reported to cause some gastrointestinal problems including vomiting, nausea, and even gastrointestinal bleeding. 
Phentermine itself is not a common allergen, but any of the ingredients can trigger an allergic response in a person. Phentermine is known to cause tingling and skin flushing in some individuals. Urticaria (hives) is a reported side effect in some cases.
Phentermine has been reported to induce loss of libido and cause impotence in some individuals. 
The full list of side effects associated with Fastin is quite long. 
Depression and Psychological
There are no clinical trials examining the link between Fastin and depression. However, Phentermine is chemically-similar to amphetamine, and abuse of amphetamines and related drugs may be associated with intense psychological dependence. There are reports of patients who have increased the dosage to many times that recommended. Abrupt cessation following prolonged high dosage administration can result in extreme fatigue and depression. 
Dysphoriais a general dissatisfaction with life. While no clinical trials have linked phentermine or Fastin to dysphoria, stimulants – particularly potent ones like phentermine – should not be used to deal with general unhappiness. Using Fastin or any phentermine product as a mood booster is a recipe for disaster.
We recommend that you talk to your doctor about Fastin before taking it or any powerful supplement.
Fastin Health Risks
The FDA contacted Hi-Tech Pharmaceuticals in 2015, warning them about falsifying Nutrition Label information in statement dismissing Methylsynephrine as a dietary ingredient. 
There are always health risks associated with excessive caffeine intake. One 245 mg tablet of Fastin contains about a cup and half of coffee. If someone were to take Fastin 3-4 times per day, their caffeine intake could quickly spiral out of control.
A study was conducted by the U.S. National Library of Medicine to examine the cardiovascular risks of phentermine specifically. 
Here are some of the findings from the study:
Phentermine (Fastin) is approved for short-term obesity treatment in conjunction with lifestyle modifications, but is commonly used chronically. Cardiovascular data associated with long-term use of phentermine and topiramate extended-release indicate that this combination may be a safe and effective option for reducing weight in overweight/obese patients at low-to-intermediate cardiovascular risk.
This review showed that combining low doses of phentermine and topiramate for the treatment of obesity minimized side effects while maintained weight loss efficacy. The side effects were tingling, taste changes and dry mouth.
This study brings up three important points:
- Phentermine was developed as a treatment for obesity, not for moderately-overweight people
- It was determined to be safe in a controlled setting in which low doses were administered
- The participants did not have any preexisting cardiovascular factors such as family history, hypertension, etc.
The health risks concern the average person wanting to lose five or ten pounds using a product made to treat obesity, with indiscriminate dosing, and without considering personal risk factors such as family medical history.
Fastin and Pregnancy
Fastin-XR also poses a specific health risk for pregnant women. Studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk outweighs any possible benefit.
Fastin Drug Test
Phentermine can give a false-positive for an amphetamine. . If you are subject to drug-testing, this is something you need to consider.
Fastin falls into the class of stimulants banned by the NCAA. If you are a college athlete, you absolutely should not take Fastin or Phentermine in an attempt to drop weight. 
What is the Cost of Fastin?
Approximately $19.99 for 30-ct container or $29.99 for a 45-ct container of the original formula though most retailers. Fastin also includes a money-back guarantee (MBG) if the user is dissatisfied.
A 90-ct bottle of Fastin-XR is advertised at $69.95 on the Hi-Tech Pharmaceuticals website.
Where to Buy Fastin?
Fastin can be purchased at GNC, Wal-Mart, Jet.co, eSupplements.com, or almost anywhere supplements are sold. It can also be purchased directly from the Hi-Tech Pharmaceuticals website.
For those combating obesity, the directions are to ingest one capsule at approximately 2 hours after breakfast for appetite control. Late evening medication should be avoided because of the possibility of resulting insomnia.
The directions from Hi-Tech Pharmaceuticals are to take one-two tablets in the morning and 1 tablet after lunch. These directions also say not exceed four tablets daily. This comes from the 245 mg tablet bottle.
As the user acclimates to the product, the temptation may be to take more than the recommended dose. We cannot discourage this strongly enough. Fastin-XR is extremely potent, and as the dosage increases so does the potential for adverse and even dangerous side effects.
The dosing from Hi-Tech seems very high compared to the dosing suggestions that came from the doctors that formulated Fastin for obese patients. Additionally, the dosing recommendations from Hi-Tech do not account for a person’s size; it seems illogical to recommend a same dose to a 120 lb and a 320 lb person.
Fastin Diet Plan
There is not a specific diet plan associated with Fastin because it is primarily an appetite suppressant. We like safe, smart diets such as the Mediterranean Diet. You will likely cultivate your diet plan with time and experience, but we do not recommend that you use Fastin as a crutch for a diet filled with junk food.
Fastin Calorie Content
No calories or carbs are found in the product.
Fastin: Does It Work?
In clinical settings, Fastin has been shown to promote rapid weight loss in obese people in conjunction with an appropriate diet. Effective findings in the non-obese population have been far less consistent.
What Users Are Saying
“I have lost 20 pounds since April and that is splurging on Friday nights (one night a week).”
“You do need to do your part though and increase your activity and decrease your junk food intake.”
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“… the first time I took it, I went from a size 12 to a size 5/6. I was ecstatic. Then the formula changed and did nothing but make my heart race and feel sick.”
The Bottom Line on Fastin
Fastin may be effective in clinical settings to treat obesity, but the list of side effects makes us nervous. We cannot, without hesitation, suggest Fastin as the best or safest product on the market.
If you’re researching Fastin because you want to lose weight, we understand. Our suggestion is to find one with tested ingredients and few, if any, reported side effects.
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