Fucoxanthin Review - 20 Things You Need to Know
The results of my research into Fucoxanthin were somewhat surprising. What is the benefits of brown seaweed? Can you lose weight with fucoxanthin? Our research team got to work picking apart the ingredients or components, potential side effects and
Fucoxanthin can be purchased through Amazon.
What is Fucoxanthin?
Fucoxanthin is a carotenoid pigment contained in brown seaweed and other types of seaweed. It is said to have the capability of absorbing higher amounts of light in deep water hence its survival in deeper seas. For more than thousands of years, ancestors who lived in the coastal areas sought herbal medicines from the sea.
Brown seaweed was also used as an herbal remedy for inflammatory conditions. It is also known to have fat burning properties, anti-cancer properties, anti-nociceptive properties, and antioxidant properties.
Chemically Fucoxanthin is categorized under Xanthophylls and its chemical structure is considered unique. Its chemical formula is C42H58O6. It contains 5, 6-monoepoxide and an extraordinary allenic bond which is responsible for its unique structure.
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How Did Fucoxanthin Start?
Even though Fucoxanthin was not known to man as a separate chemical which has multiple health benefits, brown seaweed was used for millennia by mainly the people living in coastal areas.
Ancient Chinese people used seafood and seaweed extensively in their day to day diet and their herbal medical remedies.
Seaweed is traditionally used for many health-related purposes in many countries. For example, in Korea, following childbirth mothers are fed with “mieok,” a soup made of a type of seaweed which is thought to provide the lost vitamins and minerals during pregnancy. 
Fucoxanthin supplement products are available in different product names and brands. These products claim to be effective in some health conditions and are said to promote weight loss. They also claim that these Fucoxanthin supplement products are effective in bringing about weight loss by way of burning fat and it is a reliable and steady effect.
According to what these product descriptions say, Fucoxanthin extract has cholesterol lowering and triglyceride absorption reducing actions resulting in improvements in cardiovascular health. It is also said that Fucoxanthin supplement aids in controlling your blood pressure levels.
Unlike other carotenoids, it is claimed that Fucoxanthin can scavenge oxygen free radicals. Also, it is said to have a skin protective action, especially from the harmful UV rays.
Many fucoxanthin supplement products also claim that these benefits are brought about without any side effects like sleep disturbances or jitteriness. However, all these claims are yet to be 100% proven by scientific studies.
Sources Of Fucoxanthin
Brown seaweed is considered the most abundant source of Fucoxanthin. However, there are other varieties of microalgae that contain high amounts of Fucoxanthin as well.
This seaweed and microalgae extracts are found in many Fucoxanthin supplement products. Some of the microalgae and seaweed species are:
- Laminaria japonica (Ma-Kombu)
- Turbinaria turbinate
- Fucus vesiculosus (Bladderwrack)
- Phaeodactylum tricornutum (Microalgae form)
- Ecklonia cava, Odontella aurita (Microalgae form)
- Sargassum family (coreanum, hemiphyllum, fulvellum, horneri)
Nutritional Value Of Seaweed
Seaweeds absorb an abundance of minerals and naturally occurring elements from the sea. This makes them a very rich source of most of the vitamins and minerals required for nutrition.
Seaweed is thought to be one of the best sources of Calcium. It is said that a serving of seaweed contains more Calcium than a cup of fresh milk. Also, seaweeds contain potassium, magnesium, zinc, and iron as minerals.
Fucoxanthin supplements usually come as an ingredient in combination with other compounds. These supplement products usually contain:
- Brown Seaweed extract containing Fucoxanthin
- Green tea extract
- Vegetable Stearate
In addition to these ingredients, these products also claim to be free of:
- Starch preservatives
- Salt and sugar
- Artificial colors and flavors
Does Fucoxanthin Work?
Brown seaweed extract containing Fucoxanthin is known to have potent weight loss promoting properties. It has been used for other health benefits for a very long time as well.
Some research and some user reviews suggest that Fucoxanthin supplement might be of use as a weight loss promoting agent.
However, to validate it as a scientifically proven product, there is no sufficient conclusive scientific research using human subjects.
Another mice study concluded that there is a nutritional and biochemical basis for the usage of Fucoxanthin supplements as an agent that promotes weight loss and prevents diabetes and obesity-related disease conditions. 
Another mice study conducted in 2010 noted that Fucoxanthin extracts taken from seaweed improved cholesterol and lipid metabolism and suppressed weight gain even in mice fed with high-fat diets. 
Fucoxanthin Benefits And Results
Fucoxanthin extract is known to have a multitude of health benefits. These include; anti-obesity and weight loss effects, anti-diabetic effects, skin protective effects, and gastric and hepatic protective effects.
Fucoxanthin supplement decreases the weight added by adipose tissue in a significant way and also regulates blood glucose levels. These effects have been shown to be beneficial in controlling and preventing obesity, diabetes, and metabolic syndrome.
Fucoxanthin also has skin protective effects. Fucoxanthin extracted from the seaweed species L. japonica is known to inhibit the activity of tyrosinase in guinea pig irradiated with UVB and suppress melanogenesis in mice who were irradiated with UVB.
Also, oral ingestion of Fucoxanthin supplement has been associated with reduced expression of skin mRNA in melanogenesis.
Furthermore, Fucoxanthin is observed to have a photo-protective action in fibroblast cells through improved antioxidant action and suppression of DNA damage.
All these studies draw the conclusion that oral Fucoxanthin supplement may minimize or get rid of the negative outcomes of UV radiation.
Fucoxanthin extract is known to be effective in Liver disease as well. It has been shown to be effective especially in Liver carcinomas. The mechanism by which Fucoxanthin exerts its Liver protective properties were studied at a molecular level using human hepatoma cell lines (HepG2).
This study showed that the viability of HepG2 cells could be reduced by Fucoxanthin. Sometimes, even low amounts of Fucoxanthin were sufficient to suppress the phosphorylation of retinoblastoma proteins which is essential for the proliferation of the cancer cells.
Details On Fucoxanthin And Weight Loss
Fucoxanthin extract is known to break down fat in the adipose tissue store of the human body. There are several mechanisms which are thought to be responsible for the fat burning action of Fucoxanthin.
The first is by way of increasing Adiponectin levels in the blood. A mice study showed that by consuming a diet supplemented with Fucoxanthin, there was a significant rise in Adiponectin (a hormone responsible for the breakdown of fat).
Also, researchers have noticed an elevation in the number of beta 3 adrenergic receptors of the rats that were given Fucoxanthin. When this happens, there is an increase in the mitochondrial respiration which elevates the metabolic rate of the body.
This, in turn, results in reduced fat stores in the body leading to weight loss.
Other mechanisms responsible for the weight loss properties of Fucoxanthin extract are through altering enzymes that regulate lipid levels (Glucose-6-Phosphate Dehydrogenase, Malic Enzyme, Fatty Acid Synthetase), elevated expression of phosphorylated ACC and phosphorylated AMPK levels are noted in animals who were administered with Fucoxanthin which causes increased fatty acid oxidation hence weight loss, and Fucoxanthin is also known to suppress adipocyte differentiation thereby reducing the fat content of the body. 
Fucoxanthin And Diabetes
Fucoxanthin extract has shown to be effective in lowering blood glucose levels. This is by way of catalyzing the secretion of DHA (docosahexaenoic acid) which increases the sensitivity of Insulin. It is also believed to regulate the Insulin levels in the blood and helps to control food and sugar cravings.
It is also thought that Fucoxanthin extract exerts its anti-diabetic action with a decrease in blood glucose levels by enhancing the uptake of glucose from the skeletal muscles via increasing the expression of GLUT4 receptor action.
Fucoxanthin And Cancer
Some studies have shown that Fucoxanthin extract has tumor-suppressing effects. It is thought that its anti-tumor property is useful in controlling the growth of liver, gastric, and prostatic cancers and Hodgkin’s & Burkitt’s lymphomas. Fucoxanthin achieves this control over cancer cells by inhibiting the action of certain proteins responsible for the proliferation of cancer cells. 
Fucoxanthin And Inflammatory Conditions
Seaweeds, especially the brown ones are known to have anti-inflammatory properties since ancient times and it has been used as an herbal remedy in many traditional medical practices.
Fucoxanthin is the chemical compound which is responsible for this effect of the seaweeds. LPS (Lipopolysaccharides) induced inflammatory responses are what Fucoxanthin is most effective against. It is shown to bring about these effects by increasing the secretion of nitric oxide and cytokines.
Fucoxanthin is thought to be effective and potent as Prednisone in very high concentrations.
Fucoxanthin And Bone Metabolism
Out of the Fucoxanthin containing seaweeds, Sargassum fusiforme is believed to increase the formation of osteoblasts (bone forming cells) and suppress the differentiation of osteoclasts (bone-destroying cells). This results in an increase in bone density which is helpful in conditions like osteoporosis.
General Consumer Impression On Fucoxanthin
As with any other supplement, Fucoxanthin extract too has attracted widespread praise mainly as a weight loss promoting agent while getting some negative feedback in the meantime.
Many consumers have had concerns over the six week period which the Fucoxanthin supplement takes to start giving results. So, a lot of them have discontinued using the Fucoxanthin supplement after using it for two or three weeks and not have desired results.
In the meantime, there have been satisfied consumers who have not only lost weight but also felt energetic and refreshed.
Although the Fucoxanthin supplement is considered safe and side effect free, a few consumers have noted some changes like disturbances in bowel movements, stomach pains & gastrointestinal disturbances, headaches, etc.
So, as with any product, Fucoxanthin too has had positive and negative remarks owing to the reason that the individual factors, environmental and genetic factors can come into play when producing the outcome of Fucoxanthin therapy.
How To Use (Take) Fucoxanthin
Approximately 2.4-8 mg of 100% Fucoxanthin has proven to be effective in a few human studies conducted by researchers. However, higher doses than that have not been studied extensively and there is no sufficient data to comment on the safety or effectiveness.
But, practically, small dosages of 100% Fucoxanthin is not accurately measurable. Therefore a 25% Fucoxanthin extract is available to be taken in a 9.6-32 mg dosage.
Taking 20 mg a day is considered a healthy starting dose. It is shown that there is increased absorption of Fucoxanthin when taken along with fatty acids (fish oil) or Linoleic acid in its conjugated form.
Potential Fucoxanthin Side Effects
The only known side effect of Fucoxanthin supplement is the risk of thyroid function disorders caused by increased levels of Iodine.
Iodine is ingested into the body in excessive amounts when people consume lots of seaweed since there is no pure Fucoxanthin available.
It is always better to refrain from taking increased amounts of seaweed because of the above risk. Also, for people who have had allergies and hypersensitivities to Iodine, it is advised to refrain from seaweed.
Apart from this, there have been reports of minor side effects experienced by some users. These include:
- Gastric problems
Fucoxanthin extract is known to interact with nutrients in the diet like fatty acids and some chemical compounds. Only one human study has been published with no conclusive data, so we urge caution.
The inclusion of fish oil and other medium chain triglycerides have shown to increase the percentage of absorption into the blood stream. Linoleic acid in its conjugated form is proven to have an assistive effect on the anti-obesity action on mice. 
Fucoxanthin Product Warnings
When using Fucoxanthin supplement products, even though minimal side effects have been reported, it is advisable to proceed with some degree of caution, especially if you have other coexisting medical conditions like hypertension, liver disorders, uncontrolled diabetes, and respiratory diseases.
Also, it is important to consider any medications that you are currently taking and any drug or food allergies that you have had in the past.
Consulting your doctor or your pharmacist is recommended in the above situations. Also, it is advisable to refrain from taking Fucoxanthin supplement products during pregnancy and lactation as there is no sufficient scientific evidence or information to prove its safety.
Although Fucoxanthin is thought to be contained in higher amounts in Brown seaweed and Brown seaweed extract is thought to be the go-to source for Fucoxanthin, there are many other alternative sources of Fucoxanthin as well.
Ma-Kombu (Laminaria japonica) is a healthy alternative to brown seaweed as a source of Fucoxanthin. It grows in tropical climates and is famously grown in Japan and Korea. It is a salty flavored algae which can grow up to 80 meters in height.
The whole plant is used in herbal medical remedies and it is known as a rich source of Sodium, Calcium, and dietary fiber as well.
Ma-Kombu is considered effective in treating some disease conditions and health issues.
As a source of Fucoxanthin extract, it obviously is effective in anti-obesity treatment.
Apart from that, it is also known to be effective in improving anemia, lung cancer and other cancer types, thyroiditis, high blood pressure, acid reflux disorder, amnesia and Alzheimer’s disease.
Turbinaria turbinate is a form of algae which is known to be an effective alternative source of Fucoxanthin extract. It is a marine carotenoid with a central column with triangular blades in its branches.
It is brownish cream in color and has dark brown spots all over. It commonly grows in shallow seas and found extensively in the Bahamas, the Caribbean island, and Florida.
Fucus vesiculosus (Bladderwrack) is another alternative plant source of Fucoxanthin extract. It is also known as a rich source of Iodine hence its use in thyroid-related disorders. I
n addition to Fucoxanthin and Iodine, Bladderwrack also contains algin which has laxative properties making it a good choice for people with constipation to attain sufficient bowel movement.
Bladderwrack is known to be beneficial in arthritis, arteriosclerosis (hardening of arteries), digestive disorders, bronchitis, urinary tract disorders, anxiety, and of course, obesity. 
What Users Are Saying
“I’ve only been taking Fucoxanthin for three weeks now. I know that it takes a whole six weeks to completely kick in for weight loss, but I’m starting to feel a lot more energetic. I am able to wake up refreshed and feel awake the entire day! That’s amazing. Hopefully this, along with my proper diet and exercise, will help me lose some excess weight too. I would definitely recommend this product.”
“I’ve used it as instructed, but don’t see much difference.”
“This done nothing fo is to give me energy. I waited for BETTER results. But I appear more tired than usual. I’m very disappointed!!!”
The Bottom Line on Fucoxanthin
So, the moment you’ve been waiting for: our final thoughts on Fucoxanthin. Well, we like that it’s readily available and that we found some favorable customer comments, but the lack of research supporting the weight-loss claims leaves us a bit concerned.
If you want to burn fat and lose weight, we suggest going with a supplement doing both, with the help of some clinically-tested ingredients.
Among the best supplements we’ve researched this year is one called Burn HD. The product contains some clinically-tested ingredients and has been shown to help accelerate metabolism and jump start fat loss. People are talking about seeing great results and no one is mentioning negative side effects.
Also, the company that makes Burn HD is so confident in their supplement; they’re offering customers a 2-Week Sample.Learn More About Burn HD »