Updated: 05/23/2017
By Luis Miguel Apr 10, 2017

A supplement supporting leptin production, fat-loss and weight-loss. We took an in-depth look into LeptiBurn ingredients, any relevant side effects and clinical research. Additionally, we dissected hundreds of verified comments. Then, we summarized everything to give you just the information you need.

LeptiBURN Readers: Click here to find out why we're giving away samples of our product, Dietspotlight Burn.

What is LeptiBURN?

First off, LeptiBURN is a fat-burner. The ingredients are green tea extract, irvingia gabonensis, 5-Hydroxytryptophan and aframomum melegueta seed. You take two pills, twice a day. With regular use, you’re supposed to notice improvements in fat-loss, while breaking through weight-loss plateaus.

Biotrust Nutrition, founded in 2012, makes LeptiBURN 2.0. The official website sells the supplement, as well as trusted online retailers. We like the good BBB rating and that we located a few positive customer comments, but read on…

Weight-Loss Ingredients – “Effective”

The first thing we looked at was the effectiveness of Biotrust LeptiBURN ingredients. “It’s promising when a supplement contains researched ingredients,” said our Research Editor. “That means there’s a chance dieters will notice results.”

A dieter reported, “Been using this for three months and the weight loss has been paced and steady.”

“I lost weight using this product. I also do aerobic exercises everyday for one hour and thought that would be helpful especially after the “cheat” day,” commented another.

One said, “It’s not a miracle product there are things you must do i.e., exercise, eat right, and if you do, it works!”

According to another dieter, “It does seem to reduce hunger pangs and give you more energy, but I have not lost weight yet.”

Biotrust LeptiBURN Side Effects – “Positive Reactions”

We took a close look at LeptiBurn side effects. “After taking LeptiBurn for 2 days I had a headache. I wasn’t hydrating my body,” reported a customer.

One says, “No side effects experienced.”

Another stated, “I have been on LeptiBurn for about 2 months, and have no side effects at all. ”

Based on our research, users notice long-term success when there’s no chance of harmful side effects. There’s a benefit to dieters when they don’t experience adverse reactions while using LeptiBurn.

The Science – “Any Evidence?”

The official LeptiBURN website states the ingredients are added in “scientific amounts”. Studies on the website are not as supportive as we’d like to see, but we do know the caffeine and green tea [5] are two of the better additions to the formula. In total, there are more than 25 studies listed to support the benefits of the key elements. At DietSpotlight, research is a critical part of choosing the best product.

The Bottom Line – Does LeptiBurn Work?

Will LeptiBurn help you lose those pounds? There’s a chance. We like the longevity of the company and that it uses some natural ingredients. We also like that there’s research supporting the key elements in the formula.

If you want to improve weight-loss, you may want to consider adding a supplement to your regimen containing ingredients supported by research and positive reviews.

Among the best products we’ve seen this year is called Dietspotlight Burn. The formula is a proprietary blend of four ingredients that science and studies say can help increase metabolism, decrease hunger and boost fat loss. The testimonials we’ve encountered across the web show just how well people do.

Also, the people who make Dietspotlight Burn don’t want you to take their word for it, so they’re offering a Special Trial Offer, which is a good sign.

LeptiBURN Ingredients and Supplement Facts

Serving Size: 2 Capsules
Serving Per Container: 60
Amount per Serving % DV
Green Tea Extract (45% EGCG) 500mg *
Irvingia Gabonensis Extract (IGOB131) 150mg *
5-Hydroxytryptophan 100mg *
Aframomum Melegueta Seed 40mg *

Other Ingredients: Gelatin, rice flour, magnesium stearate, sililcon dioxide

We thoroughly researched the Leptiburn ingredients to give you the important facts.

Green Tea Extract

Unlike black and oolong varieties, green tea is unfermented. This herb is well known for its health benefits. In fact, it has been used to lower blood pressure, treat high cholesterol levels, boost immune system health and assist with obesity. It’s also called camellia sinensis, and is used in many dietary supplements.

What is it Supposed to Do?

Often green tea is said to help boost metabolism and reduce body fat. It contains EGCG (antioxidants) and the stimulant caffeine. This tea may also increase energy levels and improve mental focus.

Clinical Research

Some research has linked green tea to heart disease prevention. For instance, a 2006 study published in the Journal of the American Medical Association concluded that, “Green tea consumption is associated with reduced mortality due to all causes and due to cardiovascular disease but not with reduced mortality due to cancer.” [1]

Irvingia Gabonensis Seed Extract

Commonly known as African mango fruit, irvingia gabonensis is a tree that grows in Central and West Africa. The seeds of this fruit are often used for medicine. This plant has been used to treat obesity, diabetes, and high cholesterol levels.

What is it Supposed to Do?

The claim is that irvingia gabonensis helps promote a feeling of satiety, while lowering fat and cholesterol levels. Often this extract is used in over-the-counter diet supplements. It’s sometimes combined with other herbs to promote weight-loss.

Clinical Research

According to NCBI.gov, “Irvingia gabonensis induced a decrease in weight after two weeks and after one month. Although the percentage of body fat was not significantly reduced with both placebo and IG, the waist circumference and hip circumference were significantly reduced by Irvingia gabonensis.”


Commonly called 5HTP, 5-hydroxytryptophan is a byproduct of l-tryptophan. It is sometimes used to treat depression, sleep disorders, anxiety, insomnia, headaches, PMS symptoms, down syndrome and even obesity.

What is it Supposed to Do?

5-Hydroxytryptophan is often added to diet products and weight-loss supplements to help elevate mood. This can potentially aid with weight reduction, since it may help prevent stress eating.

Clinical Research

WebMD states that, “Some clinical research shows that taking 5-HTP by mouth improves symptoms of depression. Several studies have found that doses of 150-3000 mg daily for 2-4 weeks can improve symptoms of depression. Some early research shows that 5-HTP might be as beneficial as conventional antidepressant therapy for some people.” [2]

Aframomum Melegueta Seed

To begin, aframomum melegueta is also known as grains of paradise. It is a spice, and is similar to ginger. This herb grows in West Africa, and is often used in cooking or food preparation. However, this component is also used in some supplements.

What is it Supposed to Do?

Well, aframomum melegueta may help reduce excess body fat and treat obesity. However, it appears that more clinical studies are needed to determine this.

Clinical Research

Some research revealed that, “Aframomum melegueta appears to have some anti-diabetic and anti-obese mechanisms, although neither are remarkable (the one human study conducted in humans has confirmed an increase in metabolic rate, but required both cold exposure as well as brown fat on the person in question as prerequisites).”

LeptiBURN Questions & Answers:

We combed through hundreds of user comments and experiences to offer you this helpful FAQ.

What are the side effects of Biotrust Leptiburn?

The side effects of Leptiburn mentioned by customers include mild reactions, especially those sensitive to caffeine.

What is in Biotrust?

Biotrust Leptiburn ingredients are olive leaf extract, brown seaweed, irvingia gabonensis, panax notoginseng, green tea and yerba mate.

What is the active ingredient in Biotrust Leptiburn?

The active ingredient in Leptiburn is green tea.

Does Biotrust Leptiburn work?

The official website for Biotrust Leptiburn provides research supporting the claims.  Green tea, has been shown to boost metabolism and energy, but the effectiveness isn’t specific to this formula.

How much does one bottle of Biotrust Leptiburn cost?

One bottle of Leptiburn costs $69. If you order three, the price drops to $64 each. You can earn a further discount to $59 if you purchase six.

How do you take Biotrust Leptiburn?

You should take two Biotrust capsules twice daily. Each bottle contains 60 servings so it will last one month. You may want to drink a full glass of water with each serving.

Can I take Biotrust Leptiburn if I have a health condition?

If you’re pregnant or nursing, those with health conditions, anyone taking prescription medications or those under 18 years of age should contact a licensed physician prior to taking any dietary supplement.

What do users like about Leptiburn ?

Some users like that the company has been around for a number of years and there is the strong Better Business Bureau (BBB) rating.

What do users NOT like about Biotrust Leptiburn?

We found users didn’t like not finding Leptiburn sooner.

Is Leptiburn safe for vegetarians?

Yes, there are no animal products in the formula, and the capsules are made with vegetarian-friendly ingredients.

How long before I can expect to see results with Leptiburn ?

The official website recommends using the product for at least 60 days to see optimal results.

Who makes Leptiburn?

BioTRUST Nutrition is the makers of Leptiburn.

How do I contact Leptiburn customer service?

You can contact Biotrust Leptiburn customer service by emailing support@biotrust.com through the official website, calling 1-800-766-5086 or by mailing letters to BioTRUST Nutrition 111 Congress Ave. Suite 400 Austin, TX 78701.

Can I contact Biotrust through social media?

Yes, you can contact Biotrust through Facebook and Twitter.

Does Leptiburn offer any special deal or discounts?

Yes, Leptiburn offers deals and discounts. If you purchase three bottles, you receive a 7% discount. Purchasing six bottles and you receive a 14% savings. Another supplement we’re keeping our eye on is one called Dietspotlight Burn. Want to learn more? Click above.

Previous LeptiBURN Review (Updated February 6, 2014):

Biotrust Leptiburn - What You Should Know

LeptiBurn is a weight loss supplement from Biotrust Nutrition supplement line. According to co-founder Josh Benzoni, leptin works as the dominant hormone controlling functions of all other weight loss hormones. Increasing leptin production and restoring leptin sensitivity would, in theory, promote weight loss and help dieters break through weight loss plateaus. There is little doubt that leptin is significantly intertwined with appetite and weight control, but can an herbal formula alter leptin levels and leptin sensitivity to promote weight loss? While you think about that question, we'd like to point out Metabo Matrix is another weight loss supplement used to help dieters lose up to 30 pounds in a month.

List of Ingredients: Biotrust Leptiburn

  • Olive Leaf Extract
  • Brown Seaweed Extract
  • Irvingia Gabonensis Extract
  • Panax Notoginseng Extract
  • Green Tea Extract
  • Yerba Mate Extract

Product Features

BioTrust Nutrition does a fantastic job of breaking down the LeptiBurn formula and supporting how the ingredients promote weight loss with clinical research on its official site. Several of these ingredients are found in other diet products Meta Ignite, but also some that are unique to this formulation. There’s even a dedicated page with a long list of clinical references for consumers with questions about the efficacy of the supplement. We decided to do a little research of our own to see if the ingredients in LeptiBurn are as effective as BioTrust Nutrition claims them to be.

Olive leaf extract has some clinical support as an antibiotic, antioxidant and anti-hypertensive, but BioTrust Nutrition focuses on the extract’s ability to stimulate GLP-1 (glucagon peptide-1). We were able to locate a study by Eamon P. Rafferty, et al published in Scientia Pharmaceutica in 2011 supporting this claim. The study reported a 48% increase in plasma GLP-1 in rats given olive leaf extract. GLP-1 is associated with insulin sensitivity and decreased appetite, but ileal cells release GLP-1 when nutrients like carbohydrates, proteins and fats hit the small intestine. LeptiBurn is taken on an empty stomach thus the effects could help signal a feeling of fullness before the morning and afternoon meals essentially reducing the amount of food intake to promote weight loss. Another product that BioTrust offeres to help with weight-loss is BioTrust Low Carb Protein Powder.

Brown seaweed extract is a good source of fucoxanthin and iodine. Fucoxanthin has been named in numerous clinical studies on weight loss – most of which use rats as the study group – with positive results. Human studies are not as readily available, but we were able to find one study on obese, non-diabetic women with normal liver fat levels and no indication of non-alcoholic fatty liver disease that showed fucoxanthin, when paired with pomegranate seed oil, promoted weight loss. LeptiBurn does not contain pomegranate seed oil. Biotrust Nutrition mentions a study claiming fucoxanthin decreases leptin levels. If LeptiBurn increases leptin levels why add an ingredient that decreases leptin levels?

Irvingia gabonensis is an excellent source of fiber. Fiber is commonly added to weight loss supplements to slow digestion and promote satiety. There is some evidence the seed extract can help lower high cholesterol, but weight loss studies are not as conclusive, and not to the extent Cholestoff would. BioTrust Nutrition mentions a study that shows irvingia gabonensis increases leptin sensitivity by reducing C-reactive protein. We found the study published in the journal Lipids in Health and Disease. According to the study, participants were given 3,150 mg of irvingia gabonensis extract daily as 1,050 mg three times a day. LeptiBurn supplies just 300 mg of the extract taken as 150 mg twice daily. There is no comparison between the clinical study and the amount of extract supplied by LeptiBurn – there is simply not enough irvingia gabonensis.

Panax Notoginseng, also known as panax pseudoginseng, is not the same as panax ginseng. Clinical animal studies have shown panax notoginseng significantly reduces bleeding time. The extract may also have liver protective qualities. BioTrust Nutrition quotes a study published in the Journal of Ethnopharmacology in 2010 claiming panax notoginseng produces an anti-hyperglycemic effect as a result of improved leptin sensitivity. The study administered 200 mg/kg of panax notoginseng saponins by injection to lab rats genetically prone to diabetes. In a 200-lb human the amount of panax notoginseng required to produce comparable results would be more than 18,000 mg. Saponins are secondary metabolites found in panax notoginseng. Panax notoginseng was not injected as a whole extract.

Green tea extract and yerba mate extract are, in our opinion, the best ingredients in LeptiBurn. Both are clinically supported in human weight loss. At times, when diet supplement products are combined with healthy meal plans and programs, similar to Military Diet, they can help aid in weight loss. Other fat burning products with similar ingredients are Phytodren and Shred Jym. Green tea extract is an excellent source of caffeine and EGCG and yerba mate is a source of caffeine. BioTrust Nutrition mentions these ingredients supply caffeine, but the total amount of caffeine supplied is not noted. Dieters sensitive to caffeine may need to exercise caution when taking LeptiBurn or any supplement containing caffeine. A similar product, Zantrex, also contains Caffeine to help boost metabolism, but is unclear with how much caffeine is actually in the product.

Advantages with Leptiburn

  • All ingredients and amounts in LeptiBurn are listed online.
  • Green tea and yerba mate may promote metabolism and weight loss.

Disadvantages with Leptiburn

  • The total amount of caffeine supplied per serving is not listed.


BioTrust Nutrition claims that LeptiBurn will increase leptin levels, promote leptin sensitivity and help the dieter lose more weight. The company offers clinical-evidence for some of the ingredients. We like their satisfactory BBB rating, the strong dose of green tea extract and the addition of caffeine.
Learn More About Dietspotlight Burn »
Dietspotlight Author
About the Author:

Luis Miguel is a dedicated health writer whose mission is to help people live stronger, happier lives. At Diet Spotlight, he gets the scoop on the latest weight loss supplements to make it easier for readers to decide which ones are worth their time and money. Luis currently lives in South Florida with his wife and children. full bio

Rating: 3.8. From 618 votes.
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User Comments

111 Comments on "LeptiBURN Review"


Does this affect someone with IBS_D?

Victoria (Editor)

Hi Jeani! Because of possible interactions, please make sure to consult with your physician before taking this product.

Beth neff

Would this product be a heathy choice for a obese person with diabetes ?

Rich (Editor)

Hi Beth we have a few concerns about the product’s effectiveness and science. As far as diabetes, only your doctor can advise you on such matters.

Victoria (Editor)

Hello Beth. Please consult with your physician before taking any dietary supplement to make sure it is safe for you to use.

Chad Patel

How much caffeine is indeed in Leptiburn……and, what happens if accidentally taken less than 6…..six…..hours….before going to bed?!

Rich (Editor)

Chad, though the exact amount isn’t listed there is caffeine in both the green tea and Yerba Mate Extract.

Michelle Marshall

My question is – how many tablets are in each bottle ?
Thank you,



Victoria (Editor)

Hello Michelle. Each bottle comes with 120 capsules.

Margaret Shepherd

How does it affect Asthma and Diabetes?


I’ve been overweight all of my life, and at the advice of my brother, I started Leptiburn.

Victoria (Editor)

Hello. If you continue to have these side effects, please consult with your physician before continuing to take any dietary supplement.


I am a diabetic on insulin. How will that react to my bony. Or any bad side effects?

Richard (Editor)

Hi Elsie. Your questions are best answered by a licensed physician.

Victoria (Editor)

Hello Elsie. Please consult with your physician before taking leptiburn to make sure it is safe for you to use.

Carla nunziante

How can l order leptiburn?

Rich (Editor)

We placed Leptiburn’s info in the Q&A section

Erika smith

Are there bad side effects with leptiburn hormone support?


Need to give it time to work , i have been on weightwatchers.com for 12 months and lost 32 lbs , with this it is help me lost fat not lbs so people if you want a quit fix , stop eating cause you can lost over night because it took you more to gain it got it


I started to take the pills today.

If you feel uncomfortable with that change – good idea. There may be too much stimulant in there. We like Dietspotlight Burn because there’s just enough caffeine to get things moving.

Victoria (Editor)

Hello Erika. Please consult with your physician before taking any dietary supplement to make sure it is safe for you to use with other products.


I have taken Leptiburn for 10 days. I developed light- headedness when I get up from sitting and indigestion, as in belching incessantly. I eat super clean autoimmune paleo style. This means that I eat wild fish, grass-fed meats, vegetables, a little fruit and natural fats. I was initially more energetic due to the caffeine, but my weight loss has been minimal despite rigorous attention to weight watcher quantities, over 10,000 steps a day and 30 minutes six days a week of a progressive Jillian Michael’s program.


That was a very helpful review, thank you!


how long and how many bottles can one take to reduce the fat in the body?


yes you are right, the lazyness is the worst thing to have. Be active and stop worrying of what we have to eat each time.

Victoria (Editor)

Hello. All dieters have different weight loss results and need more of the product than others.

Brenda Stevens

Should Leptiburn be ingested on it’s own or combination with IC-5 and Why ?
Looking forward to your reply..

Victoria (Editor)

Hello Brenda. For detailed product instructions please refer to the official leptiburn website for more information.

Robert Weedon

I am currently on medications, warfarin, pregabalin, baclofen and others. How much information is available about drug interaction before signing up for a free sample and course

Victoria (Editor)

Hi! Because of possible interactions with medications, please make sure to consult with your physician before taking this product.

Alan Bird

I haven’t actually purchased any yet because I must first discover if Leptiburn has adverse effects on blood pressure. Could you by any chance let me know?

Rich (Editor)

Alan, some dieters reports side affects including fatigue and jitters. You may want to consider contacting a physician before you continue using Leptiburn.

Victoria (Editor)

Hello Alan. Please consult with your physician before taking any dietary supplement to make sure it is safe for you to use.


I have been taking Leptiburn for a month now and the plateau I had been sitting on for so long immediately disappeared and I lost 5kgs in the first month taking it. I am so happy as I had been unable to lose weight for years despite a very strict diet and workout routine. I am so pleased with this product I intend to keep using it until I get down to my perfect weight. I also have experienced no side effects .


I’ve been taking leptin burn for 2 days now and feel really really energetic and active. Been feeling more positive and less depressed. These are my honest opinions by the way


I have list three stone since mid November, that’s just over four months so I am well pleased and this is the longest I have stuck to a duet. I feel a major factor is giving up wheT products which I love but leptiburn seems to have taken away my craving for them which i alwYs experienced in the past


You have to use Leptiburn correctly for it to work. Sure it does have caffeine, but I just lowered the dose. It does help to lose fat IF YOU ARE working out and eating a proper diet. I work out and eat a mainly vegan diet, but once I started taking the pill I noticed it was A LOT easier and faster to see results. I take one to two pills per day. I think what this pill does is activates your metabolism and makes your fat more susceptible for being burned away. No pill is going to MAKE you lose weight, they can only assist you.


People are going to lose weight because of a diet plan and the pill.


Ive been using this product for over a month and ive lost 16 lbs using it. Along with IC-5 it’s really helped me tremendously. Yes it does work and Ive not had any bad side effects.


You have workout in order to lose weight ! You can’t just take this and expect the weight to fall off! Common sense here people! I have had NO side effects with this pill!

Your Name

Exactly!!!!! Thank You….


Wow, this is shocking, all of this. I have no ties to Biotrust other than my use of Leptiburn. Last year I started taking Leptiburn in February. I had no side effects to speak of and from February until August I lost two pounds each month. I stopped taking it because I was down to 108 lbs, (2lbs less than my target weight) and really didn’t want to loose anymore. Over the winter I gained back 5 lbs. I started taking it again in March. I only lost 1 lb in March but I lost 4 lbs in April. I really don’t want to loose too much more so I am going to continue with it at half the recommended dose. I can take at 8 Pm if I eat dinner late and I can sleep if I choose to or I can stay up. However, I did not expect to take these supplements and be lazy and eat like a pig. I have decreased my intake, especially snacking between dinner and bedtime as it does decrease my appetite. I am also exercising 3 to 5 days a week. So, it is not a miracle drug but I have had great results – no hair loss, no heart problems. But then again, I also do not suffer from a thyroid imbalance nor am I a cardiac patient.