Updated: 04/18/2017 - Site operated by Leptigen
By Summer Banks Apr 17, 2017

If you haven’t heard the whispers, there’s a weight loss system for 2017 that’s got executives in the diet industry interested. Out of the more than 300 products we’ve reviewed this past year, our premium supplement, a weight-control product called Leptigen, is worth a close look.

Attention: Frustrated Dieters

Leptigen delivers powerful results with safe ingredients backed by science, instead of the usual fillers found in other products.

Leptigen is produced in San Diego in a GMP-certified facility and contains a blend of these clinically proven ingredients:

  • Meratrim – an eight-week clinical study published in the journal Obesity showed Meratrim led to significant reduction in weight compared to placebo. [1] Subjects taking Meratrim also experienced smaller waist circumference, according to a study in Lipid World. [2] [3]
  • ChromeMate (chromium polynicotinate) – Research in the Journal of Medicine shows ChromeMate supports healthy blood-sugar and glucose levels. [4] ChromeMate does not claim to directly support weight loss, but research shows that a common symptom of blood sugar swings is hunger. [5] [6]
  • Green Tea Extract – shown in numerous studies, including one published in the American Journal of Clinical Nutrition, to result in moderate weight loss, when combined with a healthy diet and exercise. [7]

Leptigen also contains a small amount of caffeine (less than a cup of coffee) to stimulate the metabolism of fatty acids, but without an unpleasant jittery feeling. [8]

Leptigen Ingredients Supported by Science = Weight Loss Success!

Above graph was part of study presented at 58th Annual Meeting of American College of Nutrition, 11/12/15, Orlando FL

Meratrim, the main active ingredient in Leptigen, is produced by InterHealth, a California-based company founded in 1987 whose 15 branded ingredients are backed by 251 research publications.

According to multiple clinical studies, Meratrim can help you lose significantly more weight than with diet and exercise alone. In fact, one study on Meratrim reported dieters saw results after just two months. After eight weeks, weight was reduced by an average of 11.5 pounds and waist and hip circumference were reduced by an average of 4.7 inches and 2.4 inches, respectively, compared to placebo. Clinical research into the weight loss benefits are on-going. [9]

Give It Up For Nature

What also sets Leptigen apart is the purity of its ingredients. The product doesn’t contain artificial ingredients, fillers or binders. Also, it is gluten-free, non-GMO and made in the USA. To push Leptigen’s commitment to integrity, each ingredient has been third-party tested for purity and potency.

Each bottle contains a one-month supply of 60 capsules, and with two easy-to-swallow capsules per day some users start seeing positive results within the first several days. Many hit significant weight loss goals within that first month. Women and men both equally enjoyed these types of results.

Also, we were happy to see users experiencing results without many reports of negative side effects.
Leptigen Review

The People Behind the Formula

Our success with Leptigen comes from the high level of trust we maintain with the 400,000+ customers we’ve served over 7 years. We spent years researching thousands of products. With this knowledge, we created a “best of the best” product that not only works, but contains ingredients backed by real science.

Also, unboxing Leptigen is a nice experience. The 6-piece kit (Leptigen plus 5 free gifts) comes in an elegant branded box with custom compartments holding each item. The free gifts, which include a pedometer and 28-page glossy manual packed with expert weight-loss tips, shows our passion for supporting customers.

What’s The Deal With Leptigen? Drum Roll Please…

Our conclusion? Well, as it turns out, unlike some other weight-control supplements when used in conjunction with healthy diet and exercise, Leptigen helps you:

  • Lose more weight
  • Increase fat burn
  • Boost metabolism
Also: claim your sample of Leptigen »

Bottom Line: The Sample Is Worth It.

We are so confident in our product we’re giving away samples for a limited-time. This includes a 15-day supply of Leptigen, plus a pill case and a 33-page 21 Cheat Foods Guide. Sign up today to take advantage of same-day, worldwide shipping.

Click here if you’re interested in a 15-day sample of Leptigen. The sample has been in hot demand lately. So if you’re not able to order online now, you can check back in a few weeks to see if supplies have been replenished.

Leptigen Questions & Answers:

We scoured the internet for reviews on Leptigen to create this helpful FAQ.

What are the Leptigen side effects?

Leptigen side effects were not mentioned in any customer review or experience we found.

What is in Leptigen?

Leptigen ingredients are Meratrim, ChromeMate, caffeine and green tea extract.

What is the active ingredient in Leptigen?

The active ingredient in Leptigen is both Meratrim and ChromeMate.

Does Leptigen work?

Based on the clinical testing we found for Leptigen ingredients, you may just see some benefit. The formula may work to boost metabolism and spark fat loss. There’s also some caffeine [1] and green tea in the mix, so energy should increase as well.

How much does Leptigen cost?

A bottle of Leptigen costs $109.95 for a one-month supply, but the company offers a Special Trial Offer. One bottle supplies 60 capsules.

What is Leptigen’s BBB rating?

The Better Business Bureau (BBB) rating for the company behind Leptigen is a B.

How should I take Leptigen?

You take one capsule in the morning and another in the afternoon. You are supposed to take each serving about 30 minutes before meals.

Can I take Leptigen if a I have a health condition?

We’d love for everyone to take advantage of Leptigen’s proven ingredients, but it’s important to talk with your doctor before starting it or any other weight-loss supplement. This is especially important if you are under the age of 18, taking prescription medications, have a medical condition, are pregnant, nursing or planning on becoming pregnant.

What do users like about Leptigen?

According to Leptigen reviews, users like that they felt increased energy and saw weight-loss results in as little as two weeks to one month.

What do users NOT like about Leptigen?

The only thing we found that users did not like about Leptigen was that sometimes there was a wait when calling customer service during the busiest time of day.

Will the caffeine in Leptigen make me jittery?

There is 75 mg of caffeine in Leptigen. This is far less than you’d find in other weight-loss supplements, but just enough to be clinically proven. If you drink caffeine throughout the day and add this formula to that, there is a chance you could feel a difference [2], but jitters is not a common side effect.

Can I return my Leptigen order?

We’ve found customers that did send back their Leptigen order. According to the returns policy, you have 120 days to request a return.

How do I contact Leptigen customer service?

Leptigen customer service is available by phone at 1-800-555-3951. You can email a representative at info@leptigen.com or send a message via the contact form.

Can I contact Leptigen through social media?

Yes, you can contact Leptigen through Facebook and Twitter.

Does Leptigen come with a guarantee?

Yes, there is a 120-day money-back guarantee.

Leptigen User Tips:

Leptigen is a supplement that’s made with clinically tested ingredients that have been shown to help spark metabolism. There are always issues with every product. This is why it’s important to take note of user tips.


“Lepitigen does what it is suppose to do but it’s good to do your part also surrounding what you actually eat.”     Davell


“Anyone with a medical condition should consult with their doctor before taking any weight loss product.”       Melissa


“Hydration is important in addition to eating healthier.”       Donna


“You must follow the instructions on when to take it however.”       Ramona


“As long as you eat right, and exercise and drink plenty of water. IT will work!”       Lillian


“The first night I had trouble sleeping. I started taking it exactly 1 hour after breakfast after that, no later.”       Rola


Leptigen Side Effects:

Nowadays, weight-loss supplements are playing an important role in more and more lives, but it should be emphasized that natural alternatives don’t necessarily mean the safest avenue to travel. With any supplement there can be a side effect, and while Leptigen side effects are few and far between, each individual is different.


Restlessness can be characterized in a variety of different ways, but most commonly it’s described as a fidgety or anxious sensation with the inability to achieve relaxation, sit still, or rest.

What causes restlessness?

Restlessness can be caused by a number of pre-existing conditions like anxiety, attention deficit disorder, bi-polar disorder, or insomnia. [1] Some direct causes may include an irregular caffeine intake, or specific medications.

Increased heart rate

Increased heart rate is the speeding of the heart to 100 beats per minute or more. Also known as Tachycardia, it will typically begin in the lower ventricles of the heart, and is known to cause shortness of breath, dizziness, lightheadedness, and chest pain.

What causes increased heart rate?

Increased heart rate can be brought on by an existing health condition such as high blood pressure (hypertension), poor blood supply to the heart, muscle disease (cardiomyopathy), infections or tumors. Emotional stress, alcohol and caffeine intake are some direct causes of this symptom.


Nausea is an inclination to vomit through a sick feeling in your stomach, often times coupled with sweating, diarrhea, faintness, or fever.

What causes nausea?

Some causes of nausea include systemic illnesses (influenza for example), inner ear disease, medications, or acute gastritis (direct irritation of the stomach lining). [2] Other possible causes are motion sickness, stomach infection, or food poisoning. Your forehead may feel damp and clammy in addition to numbness of the fingers and hands.


Insomnia is the inability to fall asleep or to stay asleep during a time when sleeping is necessary. People with insomnia can become unsatisfied with their sleep routine, feeling fatigued and moody throughout the day, or generally unable to focus.

What causes insomnia?

Insomnia can be brought on by any number of factors including psychiatric disorders, anxiety, certain medications, chronic pain or unhealthy sleeping habits. Inability to sleep may leave your body feeling weak and unable to function.

Leptigen side effects are extremely rare, but that doesn’t mean they are nonexistent. There have been some reports of insomnia, increased heart rate, and restlessness, among others. Before you start any supplemental diet you should always contact a physician in an effort to avoid any potential side effects or medical issues. If you are under 18, pregnant, nursing, have a pre-existing medical condition, or are already taking medication you should seek advice from you’re your physician before taking any supplements.




We’ve never found a weight-loss supplement that didn’t cause at least a mild side effect in some users. With Leptigen, the amount of caffeine is just right to get your metabolism moving, but if the user is extremely sensitive to this stimulant, they could experience a reaction of some sort.


“It gave me a headache.”    Chelsy


“It gave me [a] stomach ache.”    Anthony


“Made me…nauseous.”    Shirley


“I do have experiences [with] mild headaches and mild stomach upset sometimes.”    Margarita


All of the Leptigen side effects we found mention of can be attributed to the caffeine. Though there is only 75mg per dose, that’s enough to cause some issues in people who are sensitive to stimulants. Over time, the body tends to get used to it and the reactions can fade away.

Leptigen is packed with ingredients with strong clinical support. They've been shown to help curb appetite, boost metabolism and increase fat loss - all supporting weight-loss. Research published in peer-reviewed journals is available.

Leptigen Ingredients and Supplement Facts

Serving Size: 1 Capsule
Serving Per Container: 60
Amount per Serving % DV
Green Tea Extract (standardized to 70% EGCG) 200mg *
Meratrim (sphaeranthus indicus flower and garcinia mangostana fruit rind) 400mg *
ChromeMate (chromium polynicotinate) 100mcg *
Natural Caffeine USP 75mg *

Other Ingredients: Gelatin, cellulose, sillicon dioxide, magnesium stearate (vegetable source)

We searched high and low through verified science to give you these facts about Leptigen ingredients.


Meratrim is a combination of sphaeranthus indicus flower heads and garcinia mangostana fruit rind.

What is it Supposed to Do?

According to research, Meratrim works to “affect…pathways involved in fat cell formation and breakdown.” You take supplements containing the ingredient twice daily. There are no safety concerns to speak of. The Food and Chemical Toxicity journal says, “the results presented herein, when combined with tolerability in the human trials demonstrate the broad-spectrum safety of Meratrim.”

Clinical Research

There are multiple studies showing the benefit of Meratrim. According to the Journal of Medicinal Food, “The primary outcome was reduction in body weight. Secondary outcomes were reduction in BMI and in waist and hip circumference.” [1] We found no reports of possible side effects.


ChromeMate is a niacin-bound chromium used in some weight-loss supplements.

What is the Supposed to Do?

ChromeMate is proven to help support healthy cholesterol levels and control levels of blood glucose. There’s also evidence it can help with weight-loss, when combined with exercise.

Clinical Research

We found support for ChromeMate in the journal Medicine & Science in Sports & Exercise. The study said, “exercise training combined with chromium nicotinate supplementation resulted in several potentially beneficial changes, including significant weight loss and a lower insulin response to an oral glucose load.” [2]

Green Tea Extract

Green tea is a variety typically grown in China or Japan. It is a form of tea that is unfermented.

What is it Supposed to Do?

There are two active elements in green tea extract that can help with weight-loss. The first is caffeine. The amount of this stimulant will differ from one supplement to the next. The second element is EGCG or epigallocatechin gallate. This polyphenol has been shown to induce thermogenesis.

Clinical Research

According to Paula Martinac, who’s earned a Master’s degree in Science and Health nutrition, “Obtaining EGCG from green tea also promotes weight loss by promoting diet-induced thermogenesis and fat oxidation.” She goes on to note that a study in the American Journal of Clinical Nutrition found, “Only the EGCG and caffeine group experienced significant energy expenditure, leading the researchers to conclude that the polyphenol has greater potential than the caffeine in green tea for promoting weight loss.”


Caffeine is the most popular stimulant in the world. It is found in sodas, coffee and some foods.

What is it Supposed to Do?

Stimulants like caffeine increase energy and promote a faster metabolism.

Clinical Research

The Mayo Clinic offers, “Caffeine may stimulate thermogenesis — one way your body generates heat and energy from digesting food.” They go on to say, “Caffeine may reduce your desire to eat.”

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Dietspotlight Author
About the Author:

Summer Banks, a content strategist at Leptigen, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 3.8. From 5676 votes.
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User Comments

87 Comments on "Leptigen Review"


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I just recieved the leptigen! I’m very excited to start it. I do have some questions, 1) Should I be taking one pill before breakfast? 2) Is just eating some fruit for breakfast okay or would you recommend something else? 3) The paper said to eat 5 small meals, I really have a hard time eating 3 meals a day. I find myself just not being hungry will that be an issue? Sorry for all the questions !

Don’t apologize for the questions Bianca. The suggested use for Leptigen is one at least 30 minutes before breakfast and the same before lunch. We advocate eating a well-balanced diet packed with healthy nutrients. That looks different for everyone. If you’re going to choose just fruit for breakfast, we’d say one with natural fiber would be a good choice.

As for the 5 small meals. We’ve heard this problem from many people. Eating smaller meals can help keep hunger at bay – so you don’t get famished and then overeat. If you don’t have trouble with hunger between meals, eating just three meals a day could be the right option for you.


I just started taking this product.and I am also going to exercise at least 20 minutes a day while taking it- as it suggests….I will update with more at the end of my trial. I will do the trial and see if it works.




Lepitigen does what it is suppose to do but it’s good to do your part also surrounding what you actually eat. Very great product. I would recommend to try.


i bought leptigen a while back, forgot i had it, i guess nows a good time to try it.

kimber lee

I have type 2 diabetes and am on Metformin and Glipizide. Will there be a problem taking this medication? I’m also on Thyroid meds.

Hi! Because of possible interactions with medications, please make sure to consult with your physician before taking this product.


I took every product you could name..ex fucoxanthin,green coffee bean extract,garcinia cambogia,fat blocker,dexatra max,alli.lymphaid,metaboup plus and this is just the beginning nothing work. I was 200lbs. Then I read about Leptigen…after 2 years of dieting and exercising nothing until 2 weeks ago I added Leptigen to my diet and started seeing a difference. I couldn’t believe it worked. Try it you will be satisfied.


I’ve been using for two weeks and haven’t noticed much of a difference yet, but will keep at it

Hey Kristal. Keep at it. The studies on the ingredients in Leptigen suggest you need to take the product for at least 6 weeks to experience significant results.

Thomas F Drury

Do you have to purchase online or is there any place I can go buy it in a store?

Hi Thomas. Right now, the only place to order Leptigen is online. However, in the future, it will be available in stores. If you’re interested in trying Leptigen, the offer here is exclusive to DietSpotlight.


Does your product offer any cleansing benefits that a probiotic might?

Hey there Jody. No, there are no ingredients in Leptigen that would “cleanse” per se. But, Leptigen does offer a cleansing product that could be what you’re looking for. Give customer service a call at 1-800-555-3951 and the success team can help you with that.

Maria khalid

I’m using it for the first time …please guide me

Welcome Maria. Leptigen is simple to use. As the label says, it is suggested you take one at least 30 minutes before breakfast and another before lunch. It is ideal to partner the powerful ingredients in Leptigen with a healthy diet and exercise program.


Hi im wondering, I’m taking some other medicine for acne is this okay for me to use still? I’m 5’0 & weigh 132 trying to go down to a 110

Hello. All users are different and can experience different side effects; please make sure to consult with your physician before taking this product.

Hi! Because of possible interactions, please make sure to consult with your physician before taking this product.


Hi, I’d like to try this but I am sensitive to caffeine. I can’t drink much coffee or tea, but chocolate doesn’t effect me (figures lol). How would you rate the strength of the caffiene? Thanks!

Tom (Editor)

Leptigen contains less caffeine than a single cup of coffee. We hardly ever see users complaining of side effects related to the caffeine. From time to time we do see comments from people especially sensitive to caffeine who say they experience mild jitters, but that’s rare.


I tried this product 2 bottles and I called them to stop my shipments. Not cause it was a bad product but because it just did not work for me . Thank you Leptigen for trying to help me . Maybe it was because I am not over over weight and I am on the tiny side so again I am so glad it works for some it just did not for me.


I am 58 years old and work out 5 days a week. I seem to be getting thicker instead of losing any weight or inches. Does anything really work for someone my age? thanks

Tom (Editor)

Hi Karen- the studies backing the ingredients in Leptigen show the product works for adults of any age. Also, we see a lot of comments from people over 60 experiencing success with the product.


I just started my sample of Leptigen about a week ago and I can tell a noticeable difference in how I feel overall. I had a problem of retaining water (edema) in my legs, and since taking Leptigen that has gone down significantly. I have also noticed that I feel more motivated & energized and am more active without thinking about it. I haven’t noticed any side effects and don’t even feel like I’ve taken anything. I can’t wait to see what a difference Leptigen makes paired up with a change in my diet and exercise!

Dee Mabuhay

Does Leptigen offer products that does not have caffeine. I cannot have caffeing because of my heart condition (AFIB). I wanted so much to lose weight but most lose weight products contain caffeine.

Welcome Dee. There is a caffeine-free version of Leptigen. Give the success team a call at 1-800-555-3951.


just placed an order for the free sample and am very excited to receive it after reading up on many reviews. I am not excessively overweight, but it wouldn’t hurt to lose a few pounds. I started a basic workout regimen about two weeks ago, and I am hoping that adding leptigen will aid in toning my body. Wish me luck!

Rich (Editor)

Good luck, Kaitlyn!


I have tried every pill on the market, gym and everything I haven’t lost any weight just money and my self-esteem . How would I know this would work

Fortuna – we’re thrilled you’re interested in Leptigen. We’ve chosen Leptigen as our Editor’s Choice because the science is there and the reviews from customers are consistently positive. There’s no fluff in there and no promises of losing 30 pounds in a week. Check out the Science and Ingredient tabs at the top. We’ve collected research there for you to read over.


How long did it take for the sample offer to arrive?

Tom (Editor)

The sample ships within 1 business day and typically takes 1-3 days to arrive.

Tom (Editor)

Excelentes resultados! Comencé Leptigen el 07/23 pesando 156.8 lbs, hoy pesé 150.0lbs!!! Perdí 6.8lbs en 12 días!!! También estoy haciendo Focus T-25 y comiendo lo más saludable posible. No he tenido ningún efecto secundario hasta el momento.

The 15 day sample is offered to help you make sure the product works with your body and also allows you to experience initial results. Fact is, over 75% of people who take the sample go on to purchase additional product from us.