Update July 28, 2017: Dietspotlight has discontinued the sale of their product, Leptigen. Leptigen was replaced by Dietspotlight Burn.
We’re constantly listening to the market whispers looking for the next popular diet trend and that’s how we developed Leptigen. We dug deep into the companies behind the available weight-loss products, tons of tested ingredients and customer reviews from third-party sites and forums. Here’s all the information on the best supplement you’re looking for.
What is Leptigen?
First off, Leptigen is a weight-loss supplement developed and sold by Dietspotlight. It is formulated with four ingredients that have good support in the research community. It’s been shown to helpmany people burn more fat and have less of an appetite. A bottle of Leptigen comes with 60 capsules; a one-month supply. You take two capsules daily – one at least 30 minutes before breakfast and lunch.
The ingredients in the formula are:
- Meratrim (400mg): Meratrim is a combination of sphaeranthus indicus flower and Garcinia mangostana fruit. If you look at research, there is some support with participants seeing a shrinking in waist and hip circumference. 
- ChromeMate (100mcg): ChromeMate is a brand of chromium polynicotinate. This is not to be confused with chromium picolinate, which is commonly used in weight-loss products. What’s interesting about this ingredient is that its primary function can support a secondary effect of weight-loss by helping keep glucose levels under control. 
- Green Tea Extract (200mg): Green tea extract is probably one of the most well-researched ingredients used in the weight-loss industry. It’s been shown to help with weight loss. This effect improves when you pair green tea with exercise.  
- Caffeine (75mg): There is a long list of benefits of caffeine, including improved motor function, increased energy and weight loss. Caffeine is a common ingredient, but Leptigen contains less than other, similar products, which could reduce the risk of side effects.
Leptigen Ingredients = Success?
We only use ingredients with a strong, direct connection to results. When Dietspotlight developed Leptigen, we had that in mind. There are numerous clinical studies on Meratrim and based on the research, the formula can help you achieve substantially more weight-loss (as compared to changes in just diet and exercise) and science hasn’t finished researching Meratrim just yet. 
Leptigen Reviews – What are Users Saying?
It used to surprise us how reviews of a product can vary so greatly, but we’ve grown accustomed to it now. There are users that lose weight and there are those that don’t – just like every other product.
This is even the case with Leptigen – Dietspotlight’s very own product.
Sarah Jo says, “I don’t usually make comments but I just had to because unfortunately there really aren’t many reviews on Leptigen from legitimate customers. I loved it. I lost 15 pounds in a month and I was lightly active with an average diet.”
Later, Dina came back to thank Sarah Jo for helping combat side effects. “Thank you so much for writing this review! It makes me feel more confident that it won’t make me sick, if I just remember to eat after taking it.”
But, there are always two sides to the story. Not all users were thrilled they tried Leptigen.
James said, “…kept me up all night with my heart pounding. I almost went to the ER. They need to make people more aware of this.”
A side effect like this is not common. Caffeine lasts about 10 hours in the body. So, if Leptigen, which contains 75mg of caffeine, is taken at 12PM, by 5PM there is 37.5mg left in the body and by 10PM there’s a good chance none is left. 
Who are the People Behind Leptigen?
The company behind Leptigen is Green Bracket, LLC – the owner of Dietspotlight.com.
What Users Are Saying
"I didn’t notice the weight loss because I forgot to keep track… but I definitely noticed a high increase in energy! Felt SO good taking this… except first couple days I had trouble sleeping.. once my body adjusted to it, I was hopping around like a rabbit (not in a crazy noticeable way, lol! And getting things done much quicker."
"Bought for my new workout regimen. Great so far"
Also: read our Burn HD Weight-Loss Kit review »
"I’m sorry, but the only thing that lost weight with this was my wallet."
Bottom Line – Is the Leptigen Sample a Keeper?
So what’s the final word on Leptigen? Well, there’s really nothing to dislike about the product. All ingredients are generally considered safe, according to WebMD. And there are both negative and positive reviews (a sign that real people who’ve tried it are willing to speak up). The only reservation we have is that 75mg of caffeine is not going to be enough for some people They may take that as the product not working when the other ingredients could be working well.
After discontinuing Leptigen, Dietspotlight developed Dietspotlight Burn. All ingredients have been clinically tested with some pretty fantastic results, and, like Leptigen, it is made in the USA.
To make it easier for people to try Dietspotlight Burn, there’s a Special Trial Offer to jumpstart weight loss.
Leptigen Ingredients and Supplement Facts
Serving Per Container: 60
|Amount per Serving||% DV|
|Green Tea Extract (standardized to 70% EGCG)||200mg||*|
|Meratrim (sphaeranthus indicus flower and garcinia mangostana fruit rind)||400mg||*|
|ChromeMate (chromium polynicotinate)||100mcg||*|
|Natural Caffeine USP||75mg||*|
Other Ingredients: Gelatin, cellulose, sillicon dioxide, magnesium stearate (vegetable source)
ChromeMate is a combination of chromium and niacin, combined to create a unique mineral complex.
What is it supposed to do?
ChromeMate assists in the balancing of cholesterol and blood sugar levels. It plays an important role in energy production and synthesis of glucose, fatty acids, and amino acids. Reports have been mixed, with some studies showing chromium to be an effective additive to a weight-loss regimen.
The International Journal of Obesity wrote that “For body weight, a significant differential effect was found for chromium picolinate.” It goes on to conclude that their meta-analysis indicated “a relatively small effect of chromium picolinate compared with placebo for reducing body weight.” A publication from Harvard Medical School stated, “A new study reports a link between chromium levels and heart attack risk: the lower the levels, the higher the risk.”
Meratrim is a unique dietary ingredient made from the extracts of the flower Garcinia mangostana and the herb sphaeranthus indicus.
What is it supposed to do?
Meratrim is said to decrease waist and hip circumference while reducing BMI (body mass index) and promoting weight-loss by preventing fat cells from multiplying. It is extremely well-tolerated, as pointed out by Food and Chemical Toxicology, “These results, combined with the tolerability of Meratrim in the human clinical trials, demonstrate the broad spectrum safety of Meratrim.”
In a systematic review using 12 randomized clinical trials, Journal of Obesity stated, “Garcinia extracts generate weight-loss on the short term.” Going on to explain that the magnitude of the effects were small and that, “Future trials should be more rigorous, longer in duration, and better reported.” The supplement is well-tolerated with no major negative side effects reported.
An extremely popular plant-based stimulant, caffeine is typically found in soft drinks, coffee beans, chocolate, teas, and some pain relievers.
What is it supposed to do?
Stimulating the central nervous system, caffeine can have a temporary energetic effect on the body, making you feel more awake and energetic.
We found a study from The American Journal of Clinical Nutrition which wrote, “Caffeine ingestion stimulates both lipolysis and energy expenditure.” It was concluded that most of caffeine’s effects are mediated through the sympathetic nervous system and that caffeine’s effects on lipid mobilization in resting conditions could be looked at in two different ways: “lipid mobilization alone is insufficient to drive lipid oxidation or large increments in lipid turnover result in small increments in lipid oxidation.”
Green Tea Extract
Green tea extract derives from a typically Asian-grown tea leaf called Camellia sinensis.
What is it supposed to do?
Green tea is packed full of powerful antioxidants called catechins. Catechins are water-soluble polyphenols that boost metabolism and assist in the burning of fat. The most important of these catechins (due to their effect on metabolism) are called Epigallocatechin gallate, or EGCG.
A report published by Chinese Medicine stated that “Long-term consumption of tea catechins could be beneficial against high-fat-diet-induced obesity and type II diabetes and could reduce the risk of coronary disease.” The report also touched on the increasing attention of green tea on diabetes and obesity, concluding that “EGCG alone has the potential to increase fat oxidation in men and may thereby contribute to the antiobesity effects of green tea.”
- 1. The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials. (2011). Journal of Obesity. January 25, 2017.
- 2. Metabolic effects of caffeine in humans: lipid oxidation or futile cycling? (2004). American Journal of Clinical Nutrition. March 9, 2017.
Leptigen Side Effects:
These days, there is an increasing number of weight-loss supplements being produced and playing important roles in more and more individual’s lives. Even though the natural alternatives may seem like the safer choice, with any supplement, there is a chance for an adverse side effect. While Leptigen side effects are relatively uncommon, individuals may have different experiences.
Restlessness is typically described as an anxious or “fidgety” feeling accompanied with the inability to relax, sit still, or even sleep.
What causes restlessness?
Restlessness is triggered by a variety of pre-existing conditions such as ADD (attention deficit disorder), insomnia and bipolar disorder. Another main cause of restlessness is anxiety. Certain medications can also trigger this symptom, as well as excessive caffeine or alcohol consumption.
Increased Heart Rate
Increased heart rate (or tachycardia) is when the human heart reaches 100 bpm (beats per minute) or more. This usually begins within the heart’s lower ventricles and has been documented causing dizziness, shortness of breath chest pain, and lightheadedness.
What causes increased heart rate?
Pre-existing health condition like hypertension, muscle disease, insufficient blood supply to the heart, tumors, and infections could cause increased heart rate, as well as alcohol consumption, caffeine consumption, and anxiety.
Nausea is the uncomfortable feeling in your stomach, typically preceding the act of vomiting. This symptom is usually accompanied by diarrhea, fever, faintness, and sweating.
What causes nausea?
Nausea can be triggered by systemic disease, acute gastritis, alcohol consumption or inner ear disease. Some other potential causes of this symptom include gallstones, food poisoning, and medicine such as nonsteroidal anti-inflammatories, aspirin, digitalis, antibiotics, and narcotics. Nausea may cause your fingers and hands to feel numb and tingly, while your forehead will usually become clammy and damp.
Insomnia is chronic sleeplessness or the inability to fall or stay asleep, usually during a period where sleep should be occurring. Individuals suffering from insomnia may become dissatisfied with their sleep habits, find it difficult to focus, and could experience feelings of fatigue and mood swings throughout the day.
What causes insomnia?
There are a large number of causes including psychiatric and medical conditions. Depression and anxiety could be a cause of insomnia, as well as medical conditions like arthritis or other such ailments that cause intense pain and discomfort. In some cases, insomnia could be triggered by specific neurotransmitters in the brain known to be linked with sleep and wakefulness.
Although Leptigen side effects are few and far between, it doesn’t necessarily mean they don’t exist for some users. Individuals have reported increased heart rate, restlessness, insomnia, and others. Before taking any supplement, it’s always best practice to consult a physician to steer yourself clear of any potential negative side effects.
If you are under the age of 18, have a pre-existing medical condition, are pregnant or nursing, or are currently taking medication, you should seek the advice of a doctor before consuming any supplement.
Leptigen Scientific Abstracts:
Green Tea Extract
Green Tea, also known as Camellia sinensis, is an unfermented variety that contains both catechins (EGCG or epigallocatechin-3-gallate) and some caffeine. Several studies have linked this plant extract to various health benefits in both humans and animals. Such benefits include cancer prevention, protection against degenerative diseases, reduced blood pressure, lessening the effects of type 2 diabetes, stronger immune system health, and even the treatment of obesity (EGCG increases fat oxidation). “Recent data from human studies indicate that the consumption of green tea and green tea extracts may help reduce body weight, mainly body fat, by increasing postprandial thermogenesis and fat oxidation.” 
Meratrim is a blend of both garcinia mangostana fruit rinds and sphaeranthus indicus flower heads. Research has been conducted to better determine the health benefits of this herbal substance. In fact, some studies have demonstrated that Meratrim is effective for the treatment of weight management in obese individuals (healthy overweight subjects). “Sixty participants with a mean BMI of 28.3 kg/m2 were randomized into two groups receiving either 400 mg of Meratrim twice daily or two identical placebo capsules for 16 weeks. At study conclusion, statistically significant reductions in body weight (5.09 vs. 1.1 kg; p < 0.0001), BMI (1.91 vs. 0.43 kg/m2; p < 0.0001). Additionally, a significant change in serum LDL (−14.79 vs. 6.25 mg/dL; p < 0.0001), triglycerides (−43.62 vs. -13.68 mg/dL; p < 0.001) and total cholesterol (−20.0 vs. -0.75 mg/dL; p = 0.0002).” 
ChromeMate (chromium polynicotinate)
ChromeMate is essentially a combination of two minerals, niacin, and chromium. A thorough analysis of this ingredient has shown that it may help lower body weight while maintaining healthy cholesterol and blood sugar levels. For instance, “One randomized, double-blind, placebo-controlled study involved subjects taking chromium or a placebo. Researchers then measured their levels of HbA1c, a marker for blood sugar levels over a period of months. 20 subjects taking 300 mcg/day chromium had significantly lower fasting blood sugar levels, as determined by HbA1c, while the placebo group saw no change.” 
“Another study, published in Physiology Genomics, was conducted with Leprdb mice, which are born obese and diabetic. The Leprdb mice typically suffer from abnormally high blood glucose and lipid profiles beginning at 30 days of life. Researchers investigated the effects of chromium polynicotinate versus placebo on the subcutaneous fat tissue of the animals using Gene Microarray Analysis, using more than 45,000 sets of the mouse genome. Chromium polynicotinate up-regulated (activated) the expression of four muscle-specific genes within the subcutaneous fat. These genes provide the signal for pre-adipocytes (fat precursor cells) to produce muscle instead of fat cells. These findings corroborate earlier studies showing that ChromeMate enhances the production of lean body mass.” 
Natural Caffeine USP
Natural Caffeine USP is high-quality caffeine taken directly from coffee beans. It is a stimulant and mild diuretic. It works by affecting the central nervous system. Some research has demonstrated that caffeine can help, “increase energy levels/physical performance, improve alertness and boost thermogenesis (the way your body generates heat and energy from digesting food).”  Also, “A series of four trials was carried out to investigate the effects of caffeine and coffee on the metabolic rate and substrate utilization in normal weight and obese individuals. Metabolic rate increased significantly during the three hr after caffeine ingestion. In conclusion caffeine/coffee stimulates the metabolic rate in both control and obese individuals; however, this is accompanied by greater oxidation of fat in normal weight subjects.” 
- 1. Beneficial effects of green tea: A literature review (2010). Chinese Medicine. May 1, 2017.
- 2. Efficacy and tolerability of Meratrim for weight management: a randomized, double-blind, placebo-controlled study in healthy overweight human subjects (2016). Lipids in Health and DIsease. May 1, 2017.
- 3. Efficacy and toxicological assessment of a novel, niacin-bound chromium in ameliorating metabolic disorders (2004). Human Clinicals. May 1, 2017.
- 4. Transcriptome of the subcutaneous adipose tissue in response to oral supplementation of type 2 Leprdb obese diabetic mice with niacin-bound chromium (2006). Physiological Genomics. May 1, 2017.
- 5. Does caffeine help with weight loss? (2017). Mayo Clinic. May 1, 2017.
- 6. Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals (1980). The American Journal of Clinical Nutrition. May 1, 2017.