Updated: 04/11/2017 - Site operated by Leptigen
By Summer Banks Mar 29, 2017

In the diet industry, don’t mistake marketing for effectiveness. We decided to put the spotlight on Metabo Up side effects, ingredients, and clinical studies. Additionally, we investigated user comments and reviews. We then summarized and condensed to give you the info you need.

Metabo Up Readers: Click here to find out why we're giving away samples of our product, Leptigen.

What is Metabo Up?

First off, Metabo Up is a thermogenic supplement from Lipozene. The ingredients are green tea, guarana seed, caffeine, oolong tea leaf, kola nut extract, cayenne fruit, and B-vitamins. When you take two capsules per day, supposedly that will help boost energy levels and ignite metabolism. A benefit is that you can take the product on-the-go.

Metabo Up was introduced in 2003 by Obesity Research Institute. It’s available to purchase on the official website and through various retailers. We do like the money-back guarantee and longevity of the company but read on…

MetaboUp Side Effects – “Stomach Turning?”

The first thing that could cause an issue is Metabo Up side effects. “Dieters expect increased energy, a boost to metabolism and more from a diet pill,” says our Research Editor. “What they don’t expect is to feel terrible after taking the product.”

“I have had diarrhea most nights with bloating of my stomach,” said one dieter.

“Bad stomach cramps and diarrhea and no weight loss. Took for 2 months, if anything I have gained weight and a bloated stomach,” offered a consumer.

While side effects may be rare, some users didn’t experience adverse reactions.

I can’t say that its given me any bad side effects,”said a customer.

Ineffectiveness – “No Results”

After reviewing forum posts, the same issues came up time and again, Metabo Up doesn’t work. Many dieters have tried it for months and haven’t noticed results. “Over the two month period my wife lost no weight. She may as well have been taking powdered sugar pills,” reported a consumer.

“Didn’t lose a pound and I took it exactly as the directions specified,” stated a user.

“Does nothing at all that I can see. No extra energy, no extra weight loss, NOTHING! Save your $$,” commented a customer.

On the other hand, we found that some dieters did notice changes. “It gives me that boost I need after lunch and helps me eat less of a supper at night,” reported a customer.

“Does exactly what it claims. It gives that little boost when you need it the most,” reported another.

We found throughout our research that any part of a supplement deemed concerning, such as ineffectiveness, the chances of long-term success are slim. If Metabo Up doesn’t produce results, there are concerns.

The Science – “What Does Research Say?”

According to the website, the Metabo Up ingredients are “clinically proven” to boost energy and metabolism. There’s solid science backing green tea and caffeine, but it doesn’t point toward this formula. Also, no studies are showing this one is a more efficient fat burner than a comparable one on the market. At DietSpotlight, we believe if there’s no science, why would a dieter want to invest any money?

Also: read our Leptigen Weight-Loss Kit review »

The Bottom Line – Does MetaboUp Work?

Hmmm, our look into Metabo Up was kind of interesting, ya know? There are some highlights like the longevity in the industry and a few positive customer comments, but we can’t recommend it because the weight-loss claims aren’t supported by published clinical research. We also have concerns about the FDA advisory, reports of negative side effects and lack of results.

If you’d like to rock your best body, we suggest going with a supplement with ingredients backed by published clinical research that’s not connected to harmful side effects.

Among the best products we’ve seen this year is our product called Leptigen. The formula consists of a four-ingredient blend, all clinically-tested with results found in studies from The American Journal of Clinical Nutrition and the journal Obesity.

Also, we’re so confident that you’ll love our supplement that we’re offering a Special Trial Offer, which is a good sign.

Previous Metabo Up Review (Updated March 6, 2014):

What You Should Know about Metabo Up

There is an official website for the weight loss product Metabo Up which tells us that the ingredients in Metabo Up are made up of a proprietary blend consisting of amino acids, and herbs such as Taurine, Arginine, Ginseng, and Theobromine. The website tells us that these ingredients will work together in Metabo Up to increase a user's metabolism and energy.

Metabo Up Ingredients

The ingredients in Metabo Up consist of a "proprietary blend" containing Taurine, Arginine, Ginseng and Theobromine.

Product Features

The official website for Metabo Up tells us that it comes in a powder stick form. Just like Meta Slim, only without a topical cream and not as expensive! We are told that if you just wish to lose a few pounds then you should mix one stick pack with eight to ten ounces of cold water. Not-so-coincidentally, other metabolism boosters like Ubervita w700 is also taken daily and blended with water. We are further told that if you wish to lose more weight in less time that you should take two sick packs of Metabo Up mixed in water. Each pack of Metabo Up consists of fourteen stick packs. The website gives a telephone number to call if you wish to order this product. Oddly, It cannot be ordered directly from the website, denoting poor service like Meta Boost. The website does not give any details on the price of Metabo Up. There is, however, a 100% money back guarantee if the product is returned within thirty days. It is difficult to undertake a proper assessment of Metabo Up as we are not given details of the exact ingredients in the product, but are only told a few of the ingredients in Metabo Up.

Advantages of Metabo Up

  • There is an official website for the weight loss product Metabo Up.
  • There is a 100% money back guarantee if the product is returned within thirty days.
  • There are details given on the official website including a telephone number for customer service.

Disadvantages of Metabo Up

  • The official website does not give a full ingredients list, but only lists some of the ingredients that are present in Metabo Up.
  • We are given no details of the price of the product on the official website.
  • You cannot order directly from the website but only by telephone.
  • We are not told what differentiates Metabo Up from other similar weight loss products for sale.


Competition amongst the manufacturers of weight loss products is tough. Heck, even competition between types of supplements is high, as Metabolite clearly shows. Consumers are information-hungry, and if there is an official website for a product they expect this website to give details regarding the price of the product and also allow curious, potential consumers to see a full product ingredients list. It's always a let-down when companies don't reveal all active ingredients; It's like Meta Ignite all over again. Unfortunately, the official website for Metabo Up, gives no price details and the information given on the product ingredients is far from satisfactory. It is impossible to make a proper assessment of this product when such essential information is lacking. We cannot therefore at the moment see why Metabo Up should be your pick above other weight loss products for sale.

Metabo Up User Tips:

7 Top User Tips

Over the years, we’ve seen that Metabo Up users have a lot to say. After carefully reading thousands of reviews and comments we put together some of the best tips to help you learn more about this product.


“Warning, do not take before going to work unless you have your own private bathroom.” Kaley


“It took months for me to really see any results, it isn’t a quick fix.” Jeff


“I had to take this with Lipozene to see any changes.” Lawrence


“You have to exercise and eat healthy to lose weight. This will help but it won’t just make the pounds fall off.” Misha


“This works ok for me but it does work slowly. You won’t lose a ton of weight overnight or even in the first few months.” Joe


“I recommend starting with half a dose to see how your body handles it. It can really make you go to the restroom.” Valerie


“I have to take this with food or it makes me wicked sick to my stomach.” Whitney

Metabo Up Side Effects:

Weight-loss supplements made with all-natural ingredients don’t guarantee safety. Even natural formulas have the ability to cause an adverse reaction. While Metabo Up side effects are rare for most users, some do experience a negative reaction.

Upset Stomach

Usually, an unclassified stomach ache is known as an upset stomach. It may not be serious enough to call it nausea yet and you may not vomit just because of an upset stomach. An upset stomach usually feels like a general icky feeling and there may not be much you can do until the germs or bacterial pass through your system. [1]

What causes upset stomach?

An upset stomach may be caused by a number of things from a common stomach bug to something you ate. It’s one of the most common side effects of supplements, herbs and medications. While it may not be serious, it may turn into something serious if your upset stomach becomes nausea or vomiting.


When you feel bloated it may be an intense feeling of fullness. However, you may feel full of air instead of food. It may also present itself at a feeling of fullness from liquid. Regardless, bloating is an uncomfortable feeling and may come along with a protruding belly.

What causes bloating?

Bloating may be cause by something you ate or something you took, such as a supplement or medication. It may also be caused by swallowing too much air or drinking too much alcohol. Many common illnesses cause the discomfort of bloating, as well.


When you cannot get to sleep or you don’t get good, regular sleep, you may be suffering from insomnia. Even if you’re able to fall asleep, if you wake up too early, wake up feeling tired or you can’t get back to sleep after waking up, you may suffer from insomnia.

What causes insomnia?

There are two types of insomnia with different causes: Acute and Chronic. Acute insomnia is usually temporary and caused by life stress, such as a death, moving, divorce or job loss. It may also be caused by illness, medications or interruptions to your normal sleep schedule. Chronic insomnia isn’t temporary and it’s far more serious. It’s usually caused by anxiety, depression, regular stress or a more serious illness causing discomfort or pain at night. [2]


Loose, liquid stools happening more than three times in a one-day period is known as diarrhea. It may be a sign of something serious or just a temporary illness.

What causes diarrhea?

Stomach viruses, bacterial infections, food poisoning and many medications may cause diarrhea. It’s usually not a sign of something serious, but if it becomes severe diarrhea (more than 10 times in one day), it may be a symptom of a serious illness. Diarrhea may also cause dehydration, which can become very serious.

Metabo Up side effects are rather uncommon, but users have reported experiencing an upset stomach, bloating, insomnia and diarrhea. It’s always important to consult with a physician before starting any new supplements, especially if you suffer from a current medical condition, are on prescription drugs, are under 18 years of age or if you’re pregnant or nursing.

MetaboUP promises a blend of "clinically proven" ingredients. The formula is all natural, but you won't find the label on the official website. Just a description of each and what they are supposed to do for your body.

Metabo Up Ingredients and Supplement Facts

Serving Size: 2 Tablets
Serving Per Container: 30
Amount per Serving % DV
Vitamin B6 600mcg 30%
Vitamin B12 15mcg 250%
Proprietary Blend 952mg *
- Green Tea Leaf Extract * *
- Guarana Seed Extract * *
- Caffeine 120mg *
- Oolong Tea Leaf * *
- Kola Nut Extract * *
- Cayenne * *
- Platycodon Root Extract * *

Other Ingredients: None

We took a close look at the Metabo Up ingredients so we could provide the important facts and specifics.

Green Tea Leaf Extract

This is an unfermented tea that is often consumed for its health benefits. Green tea has been linked to heart health, cancer prevention, low cholesterol levels and weight reduction. It is found in a number of herbal diet pills as well.

What is it Supposed to Do?

Green tea contains EGCG (antioxidants)[1] and caffeine (a stimulant)[2]. These ingredients work together to help boost metabolism and aid with fat loss. This herb also helps increase immune system health/strength.

Clinical Research

“Clinical studies suggest that green tea extract may boost metabolism and help burn fat. One study found that the combination of green tea and caffeine improved weight-loss and maintenance in people who were overweight and moderately obese,” says the University of Maryland Medical Center.

Guarana Seed Extract

Sometimes called Paullinia cupana or Brazilian cocoa, this is a tropical plant that grows in the rainforests of Brazil. It’s often found in weight-loss supplements, and is sometimes used to treat fatigue, poor athletic performance, anxiety, headaches, malaria and lack of concentration.

What is it Supposed to Do?

Guarana contains caffeine, which is a stimulant that may help boost concentration/focus, elevate energy levels, reduce fatigue and stimulate metabolism.

Clinical Research

“A study of weight and fat loss in 67 persons taking guarana and ma huang was conducted by the Obesity Research Center at St. Luke’s-Roosevelt Hospital Center and Department of Medicine. Lead author C.N. Boozer reported the results in the March 2001 issue of International Journal of Obesity and Related Metabolic Disorders. Forty-eight people completed the study, which ran for eight weeks. The active group lost more weight and body fat than the placebo group.”


Caffeine is a stimulant that’s found in many sodas, energy drinks, diet pills, coffee beverages and teas. It is natural, and comes from plant sources such as coffee seeds, tea leaves, yerba mate and guarana.

What is it Supposed to Do?

Caffeine is used in weight-loss supplements to help boost metabolism, increase energy levels, improve focus and reduce fatigue. It may help the body burn off more calories.

Clinical Research

According to PubMed.gov, one study showed that, “High caffeine consumers reduced weight, fat mass, and waist circumference more than low caffeine consumers.”

One that contains clinically-tested ingredients and has caught out eye is one called Leptigen. Want to learn more? Click above,

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Dietspotlight Author
About the Author:

Summer Banks, a content strategist at Leptigen, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 3.8. From 74 votes.
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How Does Metabo Up Compare?

User Comments (46)


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bethany hotl

I had a drug screening and the metabolte showed cocaine l nearly lost my job

Your Name

I took two pills of this and two pills of lipozene. I took a drug test for a job and it stated I was positive for 6-MAM and notriptyline. Never took drugs other than what my Dr. Prescribed. I was mortified.

Your Name

Are you being serious. Stop doing cocaine

Wanda smith

What’s the risk if you take 3/4 metaboup in a w4 hr period

Hello. All users are different and can experience different side effects; please make sure to consult with your physician before taking this product within a 4 hour time period.


I just bought this a week ago. I feel more drained than ever and have had headaches and up set stomach…Today I was throwing up all day and my stomach has Ben ” turning” I DO NOT recommend taking these

Ventura Serna

I like the product,but have a concern,will I test positive on a dot urine test

Cameron (Editor)

One dieter warned he tested positive for 6-MAM and notriptyline.

Cameron (Editor)

You would definitely have to take this product’s ingredients to your primary doctor; only they would be able to assess your risks.


im confused. am I supposed to take the metoup with the lipozene?

Candace (Editor)

It can be taken independently.

BethAnn Strauss

Does it cause constipation? I’ve been on it and am now backed up…Just curious….

Cameron (Editor)

Well, Ms. Strauss, some dieters do report upset stomach and diarrhea. The formula doesn’t contain laxatives, however.


Did you drink plenty of water I drink water all day with taking them and exercise lost 10 pounds

Linda roughan

I bought several bottles on a good special. I have carried on eating normally while taking these pills twice daily. I have not lost any weight and I have had diarrhoea most nights with bloating of my stomach. I feel these have been a total,waste of money for me.

Your Name

Yes they are I have Ben throwing up all day and have has head aches and up set stomach for a week now


dose these pills has side effect, if yes what are the side effect

Cameron (Editor)

Hey, Julianah, dieters sometimes report upset stomach, mild nausea and sometimes diarrhea.


do i need to take MetaboUP and lipozene together

Cameron (Editor)

No, you don’t. If your doctor approves you can combine it with another more suitable fat burner.

Maria morales

I been trying this product for about 2 weeks know and I have ser some changes in my body it defenetly gives me more energy and I sweet much more and faster I would totally recommend it I’m also staring to see some pounds dropped of course you have to try ur best and do exercise I do zumba in my home whenever I hv Time and it works !!


I would like to now if your able to take this product if you have diabetis and what could happen if I do. If i take it for a while till i loose some weight would that be ok. Thx


Metaboup weight loss guide…pg4. 40/40/20….and then you give meal options, nice. However, the meal options list calories only. If you are serious about people using your product and losing weight wouldn’t it be most advantageous to list protein, carbs and fat per meal options?? Makes sense to me.. ..educate your customers. Am I wrong??


what happens if u take 3 a day


I have a question do I take one capsules with the lipozene pill or take them one by one as long as it’s two pills

Cameron (Editor)

Hi ,Tabatha. When you take two capsules, once per day, the company states the product will help you lose more weight


Metabo Up plus-it DOESN’T WORK…I’m so disappointed

Your Name

I know how u feel. I get bad stomach cramps and diarrhoea and no weight loss. I have taken these for 2 months if anything I have gained wright and a bloated stomach


It really works if you really follow instructions I love it.


If I take this medication will I pass a drug screen

Stephen (Editor)

Keisha, some dieters confirm they did come up positive on tests.

loretta null

I have the pill form how many is suggested daily

Cameron (Editor)

Two capsules, once per day, Loretta.


Does it really work igot. Iam just wondering. How fast u see results


MetaboUp is for extra energy…I love it and find it works for me smile all products are diffrrent for different people. GI’ve it a try and see! I’d suggest buying at Wal-Mart though…not online smile I got a free trial offer of this and Lipozene from mt dr and I’m hoping for good results. I also workout every othrr day and drink about 3 litres of water daily.


Omg I love these also they work good. Gives energy. And I’ve lost weight in a week. just what I was looking for