Updated: 04/18/2017 - Site operated by Leptigen

MethylHex 4,2 Review - Does This Fat Burner Work?

  • 2 User Comments
  • Rating: 3.5. From 42 votes.
By Summer Banks Apr 18, 2017

My love of diet products is bested only by my passion for reviewing them 🙂 We’ve heard a lot of talk about MethylHex 4,2, so our attention turned toward ingredients, side effects, scientific research and quality of customer service. Plus, we read hundreds of testimonials and user reviews. Then, we summarized and condensed it all to give you the info you need.

MethylHex 4,2 Readers: Click here to find out why we're giving away samples of our product, Leptigen.

What is MethylHex 4,2?

Firstly, MethylHex 4,2 ingredients are caffeine anhydrous, kola nut seeds powder, yohimbe bark extract, l-alanine, bacopa monnieri extract, beta alanine, cayenne fruit powder, choline bitartrate, d-aspartic acid (daa), dmae, green tea leaf powder, guanidino propionic acid, hordenine, jaborandi leaf powder, sodium pyruvate, theobromine, white willow bark extract and yerba mate leaf powder. You’ll take one capsule in the morning and another mid-day.

MethylHex 4,2 is a fat burner introduced in 2012 by N.V.E. Pharmaceuticals; the makers of Stacker. You can purchase the supplement on the official website and through trusted retailers. We like that we found some positive customer comments and that it contains a few natural ingredients,  but read on…

Side Effects – “From the Main Ingredient?”

The first concern was MethylHex 4,2 side effects caused by the main ingredient. “This formula contains multiple stimulants,” said our Research Editor. “There’s no doubt it may boost energy levels, but the real concern is the presence of negative side effects.”

“After the first pill, I was shaky and my heart felt like it was beating out of my chest,” said a dieter.

“I used it yesterday, and you do feel as if you can workout forever, the down side is a rapid acceleration in your heart rate.” stated a customer.

On the other hand, some didn’t experience negative side effects. “It does give you a boost of energy without the effects other stimulants give you,” reported a consumer.

Lack of Results – “Losing Weight?”

Based on customer comments, MethylHex 4,2 ingredients may not help you lose weight. One dieter stated, “I needed a little boost and bought it…man I was wrong. No energy or appetite suppressant.”

“Tried it and had to stop taking. Didn’t see any changes,” reported another.

We did find some dieters that noticed results while using MethylHex 4,2.

“Lost a few pounds and inches. Pretty solid profile,” commented a customer.

“I take it before meals and I have to convince myself to eat. The appetite suppressant in this one is good,” said a user.

Our research indicates that if there’s part of a dietary supplement that’s difficult, like not producing results, long-term success is limited. If MethylHex 4,2 doesn’t help you lose weight, it could lead to a number of problems for users.

The Science – “Any Proof?”

MethylHex 4,2 claims to help users suppress appetite, burn fat and lose weight. How? There are studies showing some of the ingredients, such as caffeine and green tea, could promote weight-loss. Unfortunately, the research doesn’t relate to this formula.  In fact, there’s evidence that some of the components could lead to negative side effects. For us at DietSpotlight, a critical part of the review process is locating solid science used to support a supplement. We raise the red flag when there are no studies used to back up the available information.

The Bottom Line – Does MethylHex 4,2 Work?

Is MethylHex 4,2 the best fat burner out there? Well, we like that it contains a few natural ingredients and that we found some favorable customer comments, but we’re concerned about this one because there’s no connection between the ingredients and you losing weight. Plus, we’re skeptical about giving this one the green light because customers are talking about not seeing results and experiencing harmful side effects.

If you’d like to slim down, we suggest going with a supplement that delivers results by using proven ingredients, not connected to harmful side effects and supported by positive customer comments.

Among the best products we’ve seen this year is one called Leptigen. The supplement promotes weight-loss by featuring four clinically-tested ingredients that have been shown to help ignite fat loss and accelerate metabolism. There’s no chatter about harmful side effects, but people are excited about sharing their great results.

Also, the makers of Leptigen are so confident in their product, they’re giving new customers a Special Trial Offer, which we like to see.

Previous MethylHex 4,2 Review (Updated October 16, 2014):

What You Should Know

Do not let the world of diet products and weight loss supplements fool you. There are effective weight reduction products on the market today that can assist you with reaching your goal weight. The trick is finding the supplement, shake, liquid, or powder formula that really works for you. In this piece, we are going to examine MethylHex 4,2, which is one over-the-counter supplement for weight loss. The cost of MethylHex 4,2 is $59.99 for a bottle of 60 capsules. Just so you are aware, this dietary supplement does not come with a solid refund guarantee. Ingredients:
  • Caffeine Anhydrous
  • Green Tea Extract
  • Kola Nut
  • 4 Methylhexan 2 Amine
  • Choline Bitartrate
  • DMAE
  • Sodium Pyruvate
  • Hordenine
  • White Willow Bark
  • L-Alanine
  • Corynanthe Extract
  • Yerba Mate
  • L-Arginine
  • Capsicum

Product Features

According to online dealers, MethylHex 4,2 is supposed to help you burn away unwanted fat, suppress hunger, increase your energy levels, and even improve your mood. Like most weight loss pills, this formula is directed to be taken daily with water. However, there is no stringent diet plan or workout program recommended with MethylHex 4,2. As for user reviews, there are both positive and negative reviews posted online by dieters. A number of ingredients are revealed for MethylHex 4,2. The primary ones are Caffeine Anhydrous and Green Tea Extract. These are both sources of caffeine, which is a stimulant and diuretic. Caffeine is claimed to boost your energy levels, improve your mental focus, and help you burn off calories more rapidly. Some appetite suppressants found in this diet pill are Yerba Mate, Hordenine, and Sodium Pyruvate. Some side effects may occur if any additional caffeine is taken with MethylHex 4,2.


  • This product can be purchased with ease through online dealers.
  • MethylHex 4,2 may help improve mental focus and mood.
  • The key ingredients are explained online.


  • This weight loss product is more expensive than many others.
  • Large doses of Caffeine are found in MethylHex 4,2.
  • There are some negative dieter reviews posted online for this supplement.
  • You cannot get your money back once you buy this weight loss pill.
  • There are alternative diet products with proven ingredients.


When it comes down to it, we do not recommend MethylHex 4,2 for healthy weight reduction. First of all, this supplement appears to mostly be caffeine. This stimulant and diuretic can unfortunately lead to negative side effects like nervousness, jitters, insomnia, and dehydration. You should also consider the $60 price tag on MethylHex 4,2, and the fact that it is not sold with any kind of refund guarantee. It is prudent to investigate the weight loss market a little more, and see what else is available.

MethylHex 4,2 Side Effects:

We bring you the lowdown on MethylHex 4,2 side effects. We’ve compiled this list based on reviews by real users.


When you’re anxious, you feel frustrated, nervous, on-edge. Sometimes, you don’t know the cause of the anxiety. You feel perfectly fine one moment when all of a sudden you’re down in anxiety. Other times, the anxiety is greater than the circumstance would seem to merit. You get overwhelmed by things that are seemingly small and inconsequential. Symptoms of anxiety include shortness of breath and paliptations.

What causes anxiety?

There are many disorders that cause anxiety: general anxiety disorder, panic disorder, and stress disorders. Abnormal heart rhythms, overactive thyroid, and heart abnormalities are also known to cause anxiety.

Rapid Heart Rate

It can be dangerous when your heart beats too fast. A rapid heart rate keeps blood from flowing properly throughout your body. You typically feel your heart beating at an irregular rate. You may experience shortness of breath, dizziness, chest pain, and even fainting.

What causes rapid heart rate?

High blood pressure, overactive thyroid, and heart tissue damage can make your heart beat too fast. [1] Alcohol abuse and fever also contribute to rapid heart rate.


Jittering is when you shake and tremble spontaneously. Jittering is also associated with feelings of nervousness an anxiousness.

What causes jittering?

Many people suffer from jittering due to excessive caffeine consumption. If you have the jitters, try cutting down on beverages like coffee and tea. You may also want to review your supplements, as many of these have very high caffeine levels. Extreme stress can also cause jittering. Try reducing the amount of stress in your life in order to alleviate jittering.


Being unable to sleep properly at night can really take a toll on your health. During the day, you’re tired, irritable, and unable to focus. Insomnia includes being unable to fall asleep and having a hard time staying asleep. You may feel pain and discomfort as you lie in bed.

What causes insomnia?

Insomnia is a symptom of many conditions, including neurological disorders, arthritis, allergy, asthma, and chronic pain. [2] You may also need to adjust your nightly ritual. Habits like eating late at night and watching TV right before bed make it harder to fall asleep. Most people didn’t have any issues when using MethylHex4,2. However, you should still proceed with caution. Cease use if you begin to have side effects. Talk with your doctor about how the ingredients in this product might affect your health.

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Dietspotlight Author
About the Author:

Summer Banks, a content strategist at Leptigen, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 3.5. From 42 votes.
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User Comments (2)


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It works!! I lost 50 pounds!! Want to keep using it!!


I loved i lose10kl