Updated: 07/18/2017
By Summer Banks Jul 14, 2017

We’re all searching for the right diet product. We dug deep and wrote an in-depth review. We put the spotlight on MRM CLA 1250 side effects, ingredients, scientific research and level of customer service. Furthermore, we examined hundreds of dieter comments and forum posts. Then, we condensed and summarized to give you the info you need.

MRM CLA 1250 Readers: Click here to find out why we're giving away samples of our product, Dietspotlight Burn.

What is MRM CLA 1250?

First off, MRM CLA 1250 is a “high-potency” fat burner. The ingredients are conjugated linoleic acid from safflower oil, purified water, black carrot powder, glycerin and gelatin. [1]  Supposedly it helps speed up fat loss, reduce fat storage and retain lean muscle tissue. [2] The suggested serving is one/two capsules, three times per day.

MRM CLA 1250 was released in 2011 by Metabolic Research Modifiers. You can buy the product on the official website and through trusted retailers. We like that it provides antioxidant protection and that we found some positive customer comments, but read on…

Weight-Loss – “Lack of Real Results?”

The first thing that came up with MRM CLA 1250 ingredients was the fact that they may not work as claimed. “After doing some research on CLA, it’s clear that it has not been proven to promote weight-loss,” says our Research Editor. “If that’s the case, why is the dieter giving it a try?” [3]

One customer revealed, “Does this product do anything? Doubtful. I did lose weight on my diet and exercise regimen. So can I chalk that up to these silly pills?”

Other MRM CLA 1250 reviews stated the opposite.

“Strength and endurance baby. I sweat like an animal on this stuff and I like it,” said a user.

MRM CLA 1250 Customer Testimonials

Customer Complaints About MRM CLA 1250 – “Concerned?”

We certainly noticed a lot of user complaints posted online regarding MRM CLA 1250. In fact, one customer said, “If I were you, I would NEVER try this product. Only after 2 hours of taking ONE pill, the sorbitol added into the pills gave me diarrhea w/ anal bleeding and tightness in my chest. I can’t believe I wasted 17 dollars on this piece of crap.” [4]

“Did not notice any changes or anything at all after taking the whole bottle. Would cause me to have a slightly upset stomach after taking them but it was not enough to make me quit,” claims another user.

While some users complained about MRM CLA 1250, we found more positive experiences online. [5]

“CLA is really great to add for overall health and especially getting results regardless cutting or packing on size,” reported a customer.

“Weight stayed about the same but definitely helped my abs to show a little bit more,” offered another.

According to the research, if customer complaints are connected to any part of a supplement, long-term success could be reduced. If users have a negative perception of MEM CLA 1250, is it worth your money?

The Science – “Clinically Proven?”

At DietSpotlight, the review process relies on science and any connection to weight-loss. Regarding MRM CLA 1250, there’s no research presented on the official website. This is unfortunate, considering conjugated linoleic acid has been shown to help with the fat burning process. [6] [7] Without a direct link to you losing weight or igniting fat loss, we start to have concerns.

Also: read our Dietspotlight Burn Weight-Loss Kit review »MRM CLA 1250 Ingredients

The Bottom Line – Does MRM CLA 1250 Work?

Can MRM CLA 1250 help you lose weight? Well, we like that it contains natural ingredients and that we found some favorable customer comments, but the lack of research connecting it the weight-loss leaves us a bit concerned. [8] Also, reviews pointing toward the lack of results and negative multiple customer complaints makes us hesitant about giving this one the green light.

You deserve a supplement with your best interests in mind, so we suggest going with a product containing ingredients that promote weight-loss, not connected to harmful side effects and supported by positive customer comments.

Among the best products we’ve seen this year is our supplement called Dietspotlight Burn. This formula contains four ingredients, all clinically-tested and results often found in journal such as Obesity and the Journal of Medicine.

Also, we’re so confident that you’ll love our supplement that we’re offering a Special Trial Offer, which is a good sign.

Previous MRM CLA 1250 Review (Updated January 1, 1970):

MRM CLA 1250: What You Should Know

If you are getting frustrated with dieting and weight loss efforts, do not throw in the towel just yet. Dietary supplements and weight loss programs are becoming more advanced and effective. At this point, pretty much anyone can lose weight if they get on the right track. The key is being consistent and healthy. One thing you should never do is sacrifice your health to drop pounds. Knowledge will assist you with getting the body you have dreamed of, and remaining healthy for the long haul. For instance, MRM CLA 1250 is one product available to assist with weight management and body toning. You can find this supplement for sale in two different sizes, which include 90 softgels ($24.99) and 180 softgels ($44.95). Now we will elaborate on the specifics of this dietary supplement. Ingredients:
  • CLA (Conjugated Linoleic Acid) 1250mg
  • Gelatin
  • Glycerin

MLM CLA 1250: Product Features

MRM CLA 1250 is a softgel formula that is suitable for women and men alike. Put plainly, this product is claimed to help you build lean muscle tissue, and support fat loss at the same time. As you may know, the more lean muscle mass you have, the more calories your body will burn off naturally, in order to support the lean muscle. A serving of this supplement is one or two softgels, which are taken three times each day, along with major meals. CLA is the only active ingredient found in MRM CLA 1250 softgels. It is basically Conjugated Linoleic Acid, and it is commonly used in dietary supplements to improve muscle tone and support fat loss. Each softgel contains 1250mg of CLA, and according to the manufacturer, this helps speed up the fat burning process. It is also claimed to minimize the storage of fat, and prevent existing fat cells from increasing in size.

The Advantages of MRM CLA 1250

  • There are no side effects listed for MRM CLA 1250.
  • This supplement formula may help improve lean muscle tissue.

The Disadvantages of MRM CLA 1250

  • There are no ingredients used in this product to suppress appetite.
  • No special diet plan is encouraged with MRM CLA 1250.
  • No clinical research results are presented to support this product.


It is clear that CLA is a commonly used ingredient in dietary supplements and weight loss products. Therefore it may offer some benefits in regards to fat loss and weight management. However, this ingredient appears to be mostly for retaining lean muscle tissue. Therefore it is commonly used in conjunction with weight training and muscle building. However, there are alternative ingredients on the market today that are specifically for fat burning and appetite suppression. Therefore we do not feel that MRM CLA 1250 is the best choice for weight reduction.

MRM CLA 1250 is nothing more than a conjugated linoleic acid softgel. It's no different from the hundred others on the market today. We found it interesting that the company offers a section to tell visitors how it works, but the information has nothing to do with the question.

MRM CLA 1250 Ingredients and Supplement Facts

Serving Size: 1 Softgel
Serving Per Container: 180
Amount per Serving% DV
Conjugated Linoleic Acid (from Safflower Oil)1250mg*

Other Ingredients: Gelatin, glycerin, black carrot powder, purified water

We decided to delve deep into the MRM CLA 1250 ingredients to give you the facts.

Conjugated Linoleic Acid

Often called CLA, conjugated linoleic acid comes from sources such as safflower oil, beef, milk and eggs. While you can certainly get this acid from your diet, it’s also available in many supplements.

What is it Supposed to Do?

There are many claims that conjugated linoleic acid [1] helps boost metabolism, support heart health and increase immune system strength. It may lower blood pressure and fight obesity by decreasing overall body fat in adults.

Clinical Research

One study posted on PubMed.gov showed that, “Given at a dose of 3.2 g/d, CLA produces a modest loss in body fat in humans.” In other words, conjugated linoleic acid may aid with weight reduction to some degree. Furthermore, WebMd states that this component can help lower blood pressure and treat obesity.


As you may know, gelatin is a colorless and flavorless food that is manufactured from animal by-products. It’s translucent and is often used to make gelling agents, cosmetics and pharmaceuticals.

What is it Supposed to Do?

Well, gelatin does not really serve a purpose when it comes to weight-loss or overall health. Instead, this substance is used to create capsule shells for all sorts of supplements. These casings hold the key ingredients until the capsule dissolves in the stomach.

Clinical Research

There is no clinical research that supports gelatin as an effective weight-loss aid. However, some studies have shown that these supplement capsules can slow down the release of key ingredients, and they’re easy to digest.


First off, glycerin [2] is a colorless and odorless compound. It’s a non-toxic viscous liquid, and it often has a sweet taste to it. It’s used in a number of supplements.

What is it Supposed to Do?

Typically glycerin is used to make the coating or capsule of a supplement. Therefore it’s not really supposed to do anything except encase the important ingredients.

Clinical Research

Studies have shown that glycerin is not harmful to human health and it breaks down easily in the stomach. There is no connection between this ingredient and weight-loss. However, it does play an important role in manufacturing softgel capsules.

Research, studies and testing are all taken into consideration when we review a product. There is some support out there for CLA, but not as much as we found with dietspotlight Burn.

MRM CLA 1250 Side Effects:

The weight-loss supplement world doesn’t guarantee safety, even with natural products. Any type of formula ingested in the body has the ability to cause a negative reaction. While MRM CLA 1250 side effects are rare, they are a reality for some users.

Chest Tightness

If you feel like the muscles around your heart are flexing, cramping or tighter than normal, you may be suffering from chest tightness. This is an uncomfortable or even painful feeling in the chest area of the body.

What causes chest tightness?

Many things may cause chest tightness and it’s not always a heart attack. Anxiety is one of the leading causes of chest tightness because you change the way you breathe when you suffer from a panic or anxiety attack. It may mimic a heart attack, but you may not be suffering from any type of heart issue. [1] Anxiety is only one cause of chest tightness. Other causes include coronary artery disease, myocardial infarction, myocarditis, hypertrophic, mitral valve prolapse, specific medications, pneumonia and even a long abscess. [2] There are several causes and chest tightness should always be taken seriously.


A general feeling of tiredness may be described as fatigue. If this feeling persists and becomes a normal part of everyday life, it may be classified at chronic fatigue syndrome.

What causes fatigue?

Fatigue may be caused by not getting enough sleep, getting poor sleep, malnutrition, over exercising, stress or a number of other things. It’s a common side effect of some medications and may be a sign of something more serious.


An embarrassing and gross stool full of liquid is known as diarrhea. Most people suffer from this issue once in a while, but when it becomes as frequent as 3 times per day, it’s more serious. Severe diarrhea starts at 10 loose stools per day, which may be sign of something very serious.

What causes diarrhea?

Food poisoning, stomach illness and medications are the main causes of diarrhea. It may also be caused by stress, anxiety or a number of different diseases. Some people suffer from diarrhea as an allergic reaction to a supplement or a specific type of food.


One of the most uncomfortable feelings is nausea. It may be associated with stomach illness and vomiting, but may not come with either one. Regardless, when you feel nauseous, it may make you feel like you don’t want to leave your bed and you just want to curl up in a ball.

What causes nausea?

Nausea may be caused by something as simple as a foul odor. However, it may also be caused by the stomach flu, specific foods, medications, food poisoning and a number of other things. Usually, the timing of the nausea and the other symptoms you suffer from will help to narrow down the real cause.

MRM CLA 1250 side effects are not guaranteed, but some reports of chest tightness, fatigue, diarrhea, nausea and other reactions have been reported. Protect yourself by consulting with your physician before taking any new supplement, especially if you’re taking prescription medication, under the age of 18, suffer from a medical condition or you’re pregnant or nursing.


Side effects are uncommon in those who take MRM CLA 1250, but a few have been described by consumers and dieters. These do not speak for the majority, but there is risk when taking any supplement.


“Maybe the dosage is too high for me it’s the first time I’ve tried (today) and while at the gym it made my heart race so fast like palpation.”    Ann


“With this, MRM CLA 1250, product I get gassy and burp a bit shortly after taking it.”    Alex


“Bad burps with fish smell…didn’t like it.”    Ed


“This product made me break out really bad.”    Alejandra


“If you are prone to breakouts like myself I would strongly advise staying away from this product. My face and body went absolutely crazy once I started taking this product.”    Lane


“The only thing this product did to me was to give me a very upset stomach and very loose stools while taking it.”    Orlando


“These pills ran my blood pressure up and caused me to be a little gittery.”    Grace


“I got terrible heartburn from the first pill that took me a week to get over.”    Mark


“No effect on me other than oily skin.”    Cesar


We are all about reducing the chance of side effects when using dietary supplements. We have notices that MRM CLA 1250 reviews are astounding with very little complaint.


MRM CLA 1250 Questions & Answers:

We boiled down hundreds of user comments about MRM CLA 1250 into this helpful FAQ.

What are the side effects of CLA 1250?

MRM CLA 1250 side effects may include diarrhea [1], chest tightness, upset stomach, nausea, and fatigue.

What are the ingredients in MRM CLA 1250?

The MRM CLA 1250 ingredient is CLA, derived from safflower seed oil [2], purified water, black carrot powder, glycerin and gelatin.

Does MRM CLA 1250 work?

There is some evidence that CLA might help reduce fat deposits. However we were unable to find any clinical evidence that MRM CLA 1250, as a supplement, works to promote weight-loss.

How much does CLA 1250 cost?

If purchased directly from the manufacturer, a one-month supply of MRM CLA 1250 is $44.95.

How should I take MRM CLA 1250?

The manufacturer recommends taking one to two MRM CLA 1250 soft gels three times a day with meals.

Can I take MRM CLA 1250 if I have a health condition?

Individuals who are under 18, have a health condition, are taking prescription medications and women who are pregnant or nursing should consult their healthcare provider before starting MRM CLA 1250, or any other supplement like it.

What do users like about CLA 1250?

Some consumers like that the single ingredient in MRM CLA 1250 is all natural.

What do users NOT like about MRM CLA 1250?

Some users do NOT like that there is little clinical evidence to support the efficacy of MRM CLA 1250.

How do I contact the MRM CLA 1250 customer service department?

You can contact MRM CLA 1250 by phone at 1-800-948-6296, by email at sales@mrm-usa.com, by writing letters to MRM Corporate Headquarters 2665 Vista Pacific Dr. Oceanside, CA 92056 or by using the feedback form on the official website.

Can I contact MRM CLA 1250 through social media?

Yes, you can contact MRM CLA 1250 through Facebook and Twitter.

Is CLA 1250 vegan?

No, MRM CLA 1250 is not vegan. While the main ingredient is derived from a plant source, the softgel contains gelatin which is derived from animal sources.

What is CLA?

CLA is conjugated linoleic acid. This is a fatty acid typically found in dairy and meat products, but is also found in some plants like the safflower.

Does MRM CLA 1250 come with a guarantee?

We were unable to find a money-back guarantee on the official MRM CLA 1250 website.

Do you know of any special deals or discounts on MRM CLA 1250?

Unfortunately, we didn’t find any special deals or discounts on CLA 1250.

MRM CLA 1250 is from a trusted company, but the research isn’t as strong as we would like to see. We prefer products with clinical support, like Dietspotlight Burn.

MRM CLA 1250 Scientific Abstracts:


In this study, the placebo group had shown more of a weight gain than the CLA group during the holiday season (P=0.01). In the placebo group, changes of weight were significantly higher in comparison to the period of time prior to the holiday (August through October) (P=0.03). There had been a six month alteration in the composition of the body which was improved with CLA as opposed to placebo (P=0.02), and body fat had been substantially decreased in the group given CLA. The rate in which negative emotions were reported had reduced by a good amount; however there had been no alterations in any of the other categories of negative reactions. CLA had no affect on insulin resistance, markers of liver function, blood lipids, and markers of inflammations in comparison to placebo. There was an exception of reduced biomarkers of endothelial dysfunction. In conclusion, CLA among adults who are overweight had greatly decreased body fat over a period of six months and had stopped weight gain during the holiday season. No adverse effects had been reported, but additional studies need to be carried out in order to evaluate the effect of CLA long-term. [1]

63 participants had finished the study (CLA, n = 30). After the 12th week, when compared to baseline, the body weight, body mass index total fat mass, waist-to-hip ratio, subcutaneous fat mass, and fat percentage had all reduced within the CLA group (P < 0.05). The body weight, body mass index, waist-to-hip ratio, and subcutaneous fat mass reduced in 27 participants with a body mass index of ≥ 27, these were all lower in female participants, with the exception of subcutaneous fat mass. Total cholesterol levels, triacylglycerol, plasma fasting glucose, and low-density lipoprotein were all elevated. CLA supplementation for a period of 12 weeks in overweight as well as grade I obese Chinese participants had displayed lower obesity indices with no reports of negative side effects. [2]

Supplementation of CLA may also elevate the lipolysis as well as decrease the gathering of fatty acids on the adipose tissue. The actions which are involved could be its action in decreasing the lipase lipoprotein activity and in elevating the carnitine-palmitoil-transferase-1 (CAT-1) activity as well as its reactions with PPARγ,in addition to raising UCP-1 expression. There have been studies made in human subjects who have shown some benefits of CLA for weight-loss; however the results are still contradictory. [3]

Learn More About Dietspotlight Burn »
Summer Banks Dietspotlight Author
About the Author:

Summer Banks, a content strategist at Dietspotlight, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 3.6. From 53 votes.
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Hi, i want to know tha oes it help in building muscle? I’m a thin person and want to gain muscle. Someone gave me these supplements but on the Internet i’ve read that these supplements are helpful to loose wait etc