Updated: 01/15/2018

Phenadrine Review - 6 Things You Need to Know


I paused before I hit the “publish” button on this one, because my conclusion was a bit of a shocker. Our focus pointed toward Phenadrine side effects, ingredients, scientific research and the quality of customer service. Furthermore, we analyzed hundreds of dieter comments and testimonials. Then, we summarized and refined to give you the info you need.

Phenadrine Readers: Click here to find out why we're giving away samples of our product, Burn HD.

What is Phenadrine?

First off, Phenadrine ingredients are senegalia beriandieri 200mg, b-phenylethylamine, methylsynephrine, n-methyl b-phenylethlyamine, n-methyl b-methylphenylethylamine, n-dimethyl, beta-phenylethlyamine, n-acetyl-l-tyrosine, caffeine, naringin, bergamottin fruit, 1,3 dimethylamylamine hcl (DMAA) and theobromine. [1] [2] The supplement promotes weight-loss by burning fat and boosting metabolism. The recommended serving is two capsules per day; one in the morning and another mid-day.

Phenadrine is made by Advanced Performance Supplements (APS). Touted as the “world’s strongest diet and energy aid,” the product first hit the market in 2010. Trusted retailers and the official website offer it for sale. We like that it contains a few natural ingredients and that it seems affordable, but read on…

Products Similar to Phenadrine

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Burn HD (Sample offer)read

Phenadrine Ineffectiveness – “No Energy Boosts!”

The first concern was the effectiveness of Phenadrine ingredients. “When supplements contain multiple stimulants, you expect to notice the changes,” said our Research Editor. “Unfortunately, customer reviews state they haven’t seen results.”

“This pill didn’t do anything but make me sleepy, nothing else,” commented a customer. [3]

Another person stated, “Not sure about Phenadrine. Says it’s an energy aid and it didn’t give me any energy.”

However, we located customers talking about results while using Phenadrine. “Take it before hitting the gym and my workout is insane. Definitely worth it,” stated a user.

Adverse Effects – “Another Potential Problem?”

Phenadrine side effects were a main concern mentioned in customer reviews. One dieter said, “Leaves a horrible burn in my stomach. I am kind of scared to take it any longer.” [4]

“Gives me a very uncomfortable pain in my stomach. It almost feels like an extreme case of heart burn, it just hits a bit lower,” commented another. [5]

On the other hand, we found some dieter experiences were on the positive side. “No headaches, jitters or anxiety,” stated a user. [6]

“One of the first fat burners that didn’t cause me to crash,” said a dieter.

Our research has shown that when any particular part of a supplement is considered concerning, such as being the cause of adverse reactions, there’s a chance that long-term success could be limited. So, if dieters use Phenadrine and the results include harmful side effects, this may be a sign to consider something different.

The Science – “Research Says…”

Science is mentioned on the official website. The makers of Phenadrine provide details about the active ingredients. What’s missing is the actual studies showing this formula is better than others and that it’s connected to weight-loss. Also, we found that multiple components are associated with adverse reactions; which isn’t mentioned. The essential part of the review process for us at DietSpotlight is scientific evidence used to back the claims. When there’s no evidence available, is it really worth your money?

What Users Are Saying

"”Best results occurred (focus and energy) when I went at least an hour before I ate after using this supplement. If I ate shortly after, I felt like I would have been better off with coffee.””"

"”“Got used to it after 6-8 weeks, the buzz went away. Ate clean and upped cardio sessions. ””"

"”“Great product. No jitters. Good energy pre workout too.””"

The Bottom Line – Does Phenadrine Work?

Now the moment you’ve been waiting for: our final thoughts on Phenadrine. Well, we like that it is easy to use and it contains some natural extracts, but we’re concerned about the lack of research connecting this supplement to weight-loss. Furthermore, we’re hesitant about giving it the green light because user reviews talk about Phenadrine ingredients causing harmful side effects.

We’re here to help you navigate through your weight-loss journey, so we suggest going with a supplement connected to ingredients backed by science, not linked to harmful side effects and backed by positive customer reviews.

Among the best products we’ve seen this year is one called Dietspotlight Burn. The supplement promotes weight-loss by using four clinically-tested ingredients, which have been shown to help ignite fat loss and boost metabolism. We can’t pinpoint any talk of harmful side effects and user comments around the web indicate people are seeing great results.

The makers of Dietspotlight Burn are offering a Special Trial Offer, which is an excellent sign of confidence in their supplement.

Learn More About Burn HD »
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What are the side effects of Phenadrine?

According to some customer reviews, Phenadrine side effects may include stomach pains, heart burn, high heart rate, and high blood pressure.

What are the ingredients in Phenadrine?

Phenadrine ingredients include senegalia beriandieri extract, b-phenylethylamine, methylsynephrine, n-methyl b-phenylethlyamine, n-methyl b-methylphenylethylamine, n-dimethyl, beta-phenylethlyamine, n-acetyl-l-tyrosine, caffeine anhydrous, naringen/bergamottin fruit, 1,3 dimethylamylamine HCl, and theobromine. 

How do I know if Phenadrine is right for me?

Choosing the right product is the #1 question asked by DietSpotlight readers. We recommend trying any product before buying it and know that finding a product with a sample offer is near impossible - so we created our own product, Burn HD, with scientifically backed ingredients.

Click here to get your sample of our powerful fat burner today.

Does Phenadrine work?

There is some clinical support for caffeine, which comes in two sources with Phenadrine. However, you have to look at the methylsynephrine. When this ingredient is combined with caffeine the risk of stimulant-related side effects increases dramatically.

How much does Phenadrine cost?

For a bottle of 60 capsules, Phenadrine costs about $59.95.

How should I take Phenadrine?

It is suggested that you use Phenadrine twice a day. One capsule should be taken in the morning and another should be taken in the afternoon. The makers highly suggest against using more than three capsules a day.

Will Phenadrine show up as a positive result for a drug test?

Since Phenadrine contains a similar chemical formula to amphetamine, you may show up positive in urine test. 

How long can I take Phenadrine?

Phenadrine can be potentially habit-forming. Makers suggest you only take the supplement for three months because of this factor.

Does Phenadrine come with a guarantee?

Phenadrine does not come with a guarantee.

If you are looking for a supplement with clinically tested ingredients, you may want to take a look at Dietspotlight Burn.

Phenadrine Ingredients

Phenadrine claims to deliver weight loss, focus, clarity, alertness, crash-free formula and a boost in energy.

Phenadrine Ingredients and Supplement Facts

Serving Size: 1 Capsule
Serving Per Container: 60
Amount per Serving% DV
Proprietary Blend750 mg*
-Senegalia Berianderi Extract**
-N-Dimethyl Beta-Phenylethylamine**
Caffeine Anhydrous**
Dimethylamylamine HCI**

Other Ingredients: None

  • References
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Previous Phenadrine Review (Updated January 1, 1970):

Phenadrine: What You Should Know

The weight loss supplement Phenadrine is manufactured and sold by the South African Company Biogen. The main active ingredients in this product include Citrus Aurantium, Green Tea Extract and Yerba Mate. These ingredients are extremely popular ingredients in weight loss products on the market today. Although there is an official website for the products produced by Biogen, it does not give any information on the purchase price of Phenadrine.


The ingredients in Phenadrine include White Willow Bark, Citrus Aurantium, Green Tea Extract, L-Tyrosine, L-Tyrosine and Octopamine.

Phenadrine Product Features

Phenadrine cannot be ordered directly from the official website for Biogen products but can only be purchased in person in pharmacies in South Africa. This will make it rather difficult for some who does not live in South Africa to purchase this product. Those who take aspirin regularly or similar medication regularly should not use Phenadrine due to the inclusion of White Willow Bark in this product. There are also a number of stimulants in Phenadrine which means that you may want to cut down on the amount of coffee that you drink if you do decide to take Phenadrine. Green Tea Extract which is present in this product is one of the most popular ingredients in weight loss products on the market today. He We are given no information as to what makes Phenadrine more effective than other weight loss supplements on the market which contain Green Tea Extract. Some experts warn that Citrus Aurantium which is present in Phenadrine may increase the risk of a stroke. It was at one time thought to be a safe alternative to the now banned Ephedrine, but not any more. There does not seem to be an offer of a money back guarantee upon purchase of Phenadrine.

Phenadrine Advantages

  • There is an official website for Biogen, the Company which manufactures Phenadrine.
  • There is a full and comprehensive list of ingredients in Phenadrine.
  • There are contact details given on the official website, should you wish to contact a representative of Biogen.

Phenadrine Disadvantages

  • Phenadrine can only be purchased in pharmacies in South Africa.
  • Some experts believe that Citrus Aurantium which is present in Phenadrine can increase the risk of a stroke.
  • Those who take aspirin regularly or similar medication should not use Phenadrine due to the inclusion of White Willow Bark in the product.
  • There is no evidence that Phenadrine is more effective than other products on the market which contain similar ingredients.


The fact that this product is only for sale in pharmacies in South Africa restricts the number of consumers who will be able to purchase this product. In any event there is no evidence that it is more effective than other products for sale which contain similar ingredients.
Summer Banks Dietspotlight Author
About the Author:

Summer Banks, Director of Content at Dietspotlight, has researched over 5000 weight-loss programs, pills, shakes and diet plans. Previously, she managed 15 supplement brands, worked with doctors specializing in weight loss and completed coursework in nutrition at Stanford University. full bio.

16 Phenadrine Reviews

  • brandy

    I bought the phenadrine extreme coz I want to lose weight but now I am having doubts as I’m on arv’s, do you think it will affect my health?

    • Cameron (Editor)

      Only your doctor could advise you on taking this supplement along with your ARV medication.

  • Nothing good
    mel (Verified User)

    After my first dose today of 1 cap at 6:20 I felt a surge of clean energy till about 8 am then after my workout I came home and fell asleep for two hours feeling very lethargic.
    Nothing good to say so far.

  •  used CLA plus Phenadrine Lipo Zero Cut from Biogen
    arina (Verified User)

    I previously used CLA plus Phenadrine Lipo Zero Cut from Biogen and it worked like a bomb! Now after nearly 2 years and I have lost about another 13 kg because I had a big emergency operation – partitional removel of my stomach due to a ulcer and closure of pyloris. My weight stayed for 18 months 46 – 48 kg. I was extremely thin. I can now see & notice my clothes (3rd wardrobe!) I am gaining weight BUT do not want to exceed 50 kg and cannot afford a 4th wardrobe! I started taking cla ^ phenadrine lipo Zero Cut again after first asking my specialist as I cannot drink anything! He said yes but the cla is fine I think the phenadrine is giving me the following and I’m only taking half if the prescribed dosage daily. I get especially when I wake up a swollen but more windy stomach AND the most nasty is the BURP the whole day with a Very UNPLEASANT SMELL!!! Can it be a side effect & must I stop taking it? I didn’t take it for 2 days now (only the CLA) & the burp, smell & windy stomach is gone Or do you think I ate something. I really NEED to know if I can or not take the Phenadrine? And lastly if I keep on with the CLA is it helpful or useless? Please reply to my email asap. Thankyou.

  • phenadrine slim stick
    alice (Verified User)

    it’s my second week using phenadrine slim stick, but i fell nausea always, i take them in the morning before my morning session and later just before 15h00

    • Montana (Editor)

      Hi Alice. We suggest you discontinue using Phenadrine Slim stick if it continues to make you feel nauseous. You may want to switch supplements as well, especially to one with positive customer reviews, like Dietspotlight Burn.

  •  works well particularly
    ntks (Verified User)

    Ladies, I used thus before for about 2mnths. It works well particularly when combine with CLA 3000, e trick is to take it after breakfast, never on an empty stomach. This way you won’t suffer the cramps. It gives loads of ernegy too, you work like a zombie @ work and you sure get that bonus you deserve

  • Yuani

    Hi. I bought a box of phenadrine slim sticks, just to find that one of the sachets is empty. How do you suppose I handle this?

  • Leaves a horrible burn in my stomach too, is this normal?
    Rhett (Verified User)

    Leaves a horrible burn in my stomach too, is this normal??? I am kind of scared to take it any longer

  •  It does not work.
    Peter (Verified User)

    I am having almost the same problems as Alan with this product. Gives me a very uncomfortable pain in my stomach. It almost feels like an extreme case of hart burn, it just hits a bit lower!

    • Montana (Editor)

      Hello Peter. We suggest you stop using Phenadrine and seek medical advise from your physician. You may also want to try another supplement that contains clinically researched ingredients, like Dietspotlight Burn.

  •  Facing side effects.
    Alan (Verified User)

    i started with the slim stick drink and within minutes got severe pains in my stomach that lasted 3o mins or so and left a nauseaus feeling the rest of the day. i waited a few days and took 2 tablets , they had exactly the same effect. too scared to take anymore .

  • Felt awful
    Veloshnee (Verified User)

    why do we have to take it for 5 days and then stop for 2 days. I just started taking it for 5 days stopped on the 6th day and felt awful, sleepy and just want to eat.

    • karen

      Hi Veloshnee. YOu should insure that you eat healthy during the period when consuming the 5 day period. There should be no reason for you to crave if you have been disciplinned during the 5 days. Alternate rather – take the tablets during the week, and rever to the Phenadrine slim stick drinks for the weekend! Great tasting and gives you that boost. Do not over indulge during your 5 day as it will affect your energy drive and is quite noticible should you stop for the 2 days if over consumed during the week..

  •  This product works great!
    Brent (Verified User)

    Hi, Brent from South Africa here. I have been using the Biogen product for a short while and it really does what is claims to do. As an appetite suppressant it works great and in conjunction with light to mild exercise you will see results. Im not too sure about THC as a result of it though.

    • Your Name

      I use Biogen Phenadrine and the “unnecessary” food cravings are a thing of the past.