Updated: 01/10/2018

I need to make a confession: I was obsessed with researching Phytodren, so we created an in-depth review, examining the side effects, ingredients, scientific research and level of customer service. Furthermore, we focused on a multitude of dieter comments posted on the internet. Finally, we summarized the facts and specifics to give you the bottom line.

Phytodren Readers: Click here to find out why we're giving away samples of our product, Burn HD.

What is Phytodren?

To start, Phytodren is an over-the-counter diet pill. It contains a blend of:

Other Phytodren ingredients include Razberi-K, phenylethylamine, panax ginseng, poppy seed extract and thermodiamine. You are directed to take one capsule prior to breakfast and lunch. Supposedly, the supplement helps boost energy levels, suppress hunger and burn off unsightly body fat. The bottle is just the right size to take with you. [1]

Phytodren was released back in 2012, although there’s no mention of the company that makes the supplement. It’s available on the official website and through trusted retailers. We like that it contains a few natural ingredients and that we found some positive customer comments, but read on…

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Burn HD (Sample offer)read

Lack of Results – “Do You Have to Worry?”

The first problem we found when reviewing dieter comments, was lack of results with Phytodren ingredients. According to the Research Editor, ”While it’s great to see that the complete label for Phytodren is provided on the official website, that doesn’t mean the formula will work for weight-loss as claimed.” [2]

One customer said, “I have not shown any results. I feel like I paid money for nothing. Very disappointed.”

Another stated, “I saw no weight loss.”

We read Phytodren reviews that stated some users did see results.

“Lost a few pounds and have increased energy,” said a customer.

Phytodren Customer Testimonials

Phytodren Side Effects – “Watch Out!”

Many customers complained of Phytodren side effects while taking this diet aid. One said, “Phytodren made me feel nauseous and jittery, and about an hour later need a nap.” [3]

“The product only made me dehydrated and did nothing else. There was no energy boost,” explained another.

While some have complained about side effects, we found others that didn’t have the same experiences.

“No side effects to note. Feeling good after taking this one,” stated a user.

“I’ve been taking for about a month and haven’t noticed any adverse reactions,” commented another.

Through our research, we have discovered that if a particular aspect of a diet product or weight-loss program is especially problematic (pills that cause side effects, high price) the likelihood of real success is minimal. In other words, if Phytodren does in fact cause problems in numerous people, this could be a serious issue. [4]

The Science – “Legitimate?”

Sadly there is no documented science presented on the official website to support Phytodren diet pills. You can easily find research into caffeine, but those pills can be purchased for less than $5 a bottle everywhere from the grocery store to a convenience market. Here at DietSpotlight, we need to see published clinical studies that show the product is truly effective for weight-loss as claimed. When that’s not available, there’s an issue the company needs to address. [5]

What Users Are Saying

“Lots of energy and almost no appetite.”

“I’ve use a lot of diet pills and this one was disappointing as all the others ones I used. I guess diet and exercise is the answer. No magic pills.”

Also: read our Burn HD Weight-Loss Kit review »Phytodren Ingredients

The Bottom Line – Does Phytodren Work?

So much to digest with this one, but what was the final verdict? It’s great to see that Phytodren is backed by a 90-day satisfaction guarantee, but we are skeptical about recommending this diet aid because it’s not supported by any real clinical data. Furthermore, the price tag on this supplement is quite high and there are numerous complaints about side effects. Fad ingredients, like raspberry ketones, add to the problems.

If you need to speed up your weight-loss results, we encourage you to go with a dietary supplement that’s easy on your wallet, backed by published clinical studies and void of fad ingredients.

Among the best product we’ve seen this year is one called Burn HD. This supplement contains a proprietary blend of four proven ingredients, which have been shown in documented clinical studies to help increase fat loss and elevate metabolism. We were not able to find any talk of negative side effects and customer feedback posted online shows people are seeing awesome results.

Also, the makers of Burn HD are confident enough in this one so they’re offering a 2-Week Sample, nice addition.

Learn More About Burn HD »
Phytodren Customers Also Bought:
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Raspberry Ketones


What are the side effects of Phytodren?

According to customer comments, Phytodren side effects include jitteriness, anxiety, irritability , sleeplessness, upset stomach and nausea.

What are the ingredients in Phytodren?

Phytodren ingredients include chromium, irvingia gabonensis , caffeine, dicaffeine malate, green coffee bean, raspberry ketones (Razberi-K), phenylethylamine, poppy seed and evodiamine (ThermoDiamine).

How do I know if Phytodren is right for me?

Choosing the right product is the #1 question asked by DietSpotlight readers. We recommend trying any product before buying it and know that finding a product with a sample offer is near impossible - so we created our own product, Burn HD, with scientifically backed ingredients.

Click here to get your sample of our powerful fat burner today.

Does Phytodren work?

Although the official Phytodren website provides what appears to be research into the benefits of some of the active ingredients, like chromium and caffeine, there are no published studies supporting the weight-loss claims.

How much does Phytodren cost?

Phytodren costs $69.95 for one bottle, $124.95 for two and $169.95 for three.

How should I take Phytodren?

You should take two Phytodren capsules per day; one in the morning and another mid-day. One bottle lasts 3 days.

Do I need to take Phytodren with food?

No, you won’t need to take Phytodren with food. The company recommends taking the capsules prior to meals.

Do I need to diet or exercise while taking Phytodren?

No, you don’t need to diet or exercise while taking Phytodren. However, eating balanced meals and adding fitness could improve results.

Does Phytodren come with a guarantee?

Yes, Phytodren comes with a 90-day money-back guarantee.

Phytodren Ingredients

Phytodren is all about "Serious" weight-loss. There's a complete list of ingredients, a product label and information from clinical studies all available on the official website. We didn't find any links to the studies or a listing of the journals where they were published.

Phytodren Ingredients and Supplement Facts

Serving Size: 1 Capsule
Serving Per Container: 60
Amount per Serving% DV
Irvingia Gabonensis150mg*
Caffeine Anhydrous100mg*
Dicaffeine Malate100mg*
Green Coffee Bean100mg*
Panax Ginseng25mg*
Poppy Seed Extract10mg*

Other Ingredients: Magnesium stearate, gelatin

We dug deep into the Phytodren ingredients to give you the details and specifics you need.


Chromax is essentially a form of chromium, which is a mineral that the body needs in small amounts. It’s found in some dietary supplements for weight management. Some foods that offer this nutrient include broccoli, potatoes, oats, tomatoes, barley, green beans and romaine lettuce.

What is it Supposed to Do?

Chromax is said to help balance blood glucose levels. It may help enhance insulin function, which is beneficial for diabetics.

Clinical Research

“One study found that women who have diabetes as a result of being pregnant improved their blood sugar control when they took chromium,” says the University of Maryland Medical Center.

Irvingia Gabonensis

More commonly called African mango, irvingia gabonensis is a type of fruit that grows in West Africa. Over the years, it has been used as medicine to treat high cholesterol levels, diabetes and even obesity.

What is it Supposed to Do?

Irvingia gabonensis is found in a number of over-the-counter diet supplements for weight-loss. The common claim is that this fruit extract may help break down fat cells and prevent new ones from forming. It also contains fiber [1], which may help reduce cholesterol levels.

Clinical Research

According to NCBI.gov, one study showed that, “Obese patients under Irvingia gabonensis treatment had a significant decrease of total cholesterol, LDL-cholesterol, triglycerides, and an increase of HDL-cholesterol.”

Caffeine Anhydrous

Caffeine anhydrous [2] is basically a dry form of caffeine. As you may be aware, this is a stimulant that’s found in natural sources like coffee seeds, tea leaves, guarana, kola nuts and yerba mate plants.

What is it Supposed to Do?

Caffeine anhydrous is often a key ingredient in energy drinks and diet pills. This stimulant has been shown to help boost energy levels, reduce fatigue, improve alertness and even stimulate metabolism[2].

Clinical Research

“Michael Yassa, an assistant professor of psychological and brain sciences at Johns Hopkins, and his team of scientists found that caffeine has a positive effect on our long-term memory. Their research, published by the journal Nature Neuroscience, shows that caffeine enhances certain memories at least up to 24 hours after it is consumed.”

We’ve been keeping a close eye on one that contains clinically-tested ingredients and supported by positive customer comments. Want to learn more about Dietspotlight Burn? Click above.

Phytodren Scientific Abstracts


There was a substantial differential effect regarding body weight in favor of chromium picolinate (WMD (weighted mean difference): -1.1 kg; 95% confidence interval: -1.8 to -0.4 kg, n=489). Based on sensitivity analysis it has been indicated that these effects greatly rely on the outcomes of a single trial (WMD: -0.9 kg; 95% confidence interval: -2.0 to 0.2 kg, n=335). Three of all the studies which were reviewed showed reports of adverse effects, showing their absence in the treatment groups. In this conclusion, from the meta-analysis, it has been suggested that a fairly minor effect of chromium picolinate in comparison with placebo for decreasing body weight. The effect’s clinical importance is up for debate and the weak strength of the outcome means these results need to be considered with caution. [1]

Irvingia Gabonensis

By the conclusion of the trial, MBW (mean body weight) for Irvingia Gabonensis group was reduced by 5.26 ± 2.37% (p < 0.0001) when compared to the placebo group by 1.32 ± 0.41% (p < 0.02). These differences between Irvingia Gabonensis and placebo groups were found to be significant (p < 0.01). Obese subjects taking Irvingia Gabonensis supplementation also experienced a substantial reduction in total cholesterol, triglycerides, LDL cholesterol, and elevated HDL cholesterol. The placebo group did not experience any changes in blood lipid components. Irvingia Gabonensis could be a useful tool for weight-loss. [2]

Caffeine Anhydrous

Substantial increases in heart rate were noticed during the 2nd and the 3rd hours of the study, and substantially higher average systolic blood pressure was noticed between weight-loss supplement group (118.0 ± 7.3 mmHg) and placebo (111.4 ± 8.2 mmHg). No drastic changes were seen in diastolic blood pressure at any point during the study. Increases in tension and confusion were noted in supplement group. In conclusion, the results indicate a significant elevation in energy expenditure within young, healthy participants after acute intake of weight-loss supplement. Additionally, intake of said supplement seems to change mood and increase heart rate and systolic blood pressure after it was taken. [3]

Green Coffee Bean

Outcomes of the study indicate green coffee bean extract is potentially effective against weight gain and fat buildup by blocking the absorption of fat and activating the fat metabolism in the liver. Caffeine was noticed to suppress fat absorption while chlorogenic acid was noted to be involved (minimally) in the slowing effect of green coffee bean extract which resulted in the decrease of hepatic triglyceride level. Phenolic compounds like feruloylquinic acid and neochlorogenic acid, with the exception of chlorogenic acid, could be used to enhance hepatic carnitine palmitoyltransferase activity. [4]


Previous Phytodren Review (Updated February 20, 2014):

What You Should Know about Phytodren

Phytodren is a weight loss supplement that promises hard core weight loss, by helping you burn existing fat, decreasing your appetite to help you feel full with less food, and make it easier to exercise by increasing your energy levels. With many supplements on the market today making that claim, it can be hard to make the right choice about which one will work best for you. Read this review to learn more about the product so you can decide whether or not you want to give it a try instead of opting for another supplement.

List of Phytodren Ingredients

Phytodren contains the following ingredients:
  • Andrean Cocoa Extract
  • Phenylethylamine (PEA)
  • Synephrine HCl
  • Hops (Humulus Lupulus)
  • Caffeine

Product Features

Phytodren is only made up of five ingredients. We do not know how much of each ingredient is in the formula, and we do not really know if they are in a proprietary blend or not, as there is little information on the official website. Andrean Cocoa Extract is a source of many stimulants and antioxidants that will help you burn fat and keep healthy. PEA is the “love drug” from chocolate, and it is known to help you feel better and enhance your mood, so now you can get the benefit without having to eat chocolate. Synerpherine HCl is the chemical cousin of ephedra, thought to provide the same fat burning effect, without the harsh side effects that caused the ban on ephedra like in 7 Day Herbal Slim. Hops is used for its mild stimulant properties, then its calming effect. Caffeine is a stimulant, found in many items, which acts as a mild fat burner. One such is Hydroxycut Black, which is a fat burner loaded with caffeine and arugula extract for activating weight loss.

Advantages of Phytodren

  • Phytodren’s 90 Day Money Back Guarantee allows you to use the supplement and still return it for a full refund.

Disadvantages of Phytodren

  • Phytodren does not tell us how much of each ingredient is in the formula.
  • This product is expensive at $70 a bottle, discounted from $97.
  • This formula is full of stimulants.
  • There isn’t really a “free” trial of this product.
  • We don’t really know if the customer testimonials are genuine or paid endorsements.


Phytodren could be an excellent product, but without seeing how much of each ingredient is in the formula, we cannot tell you how effective the product really will be. With a formula this heavy in stimulants, it should be noted to use with caution until you know how your body will respond. Never count on the supplement to do all the work for you, as it will not. For a weight loss supplement to be effective, it needs to be combined with diet and exercise. It can help you lose more weight compared to diet and exercise alone, but will not produce much results on its own. If you are sensitive to stimulants, we do not recommend this product for you.
Summer Banks Dietspotlight Author
About the Author:

Summer Banks, Director of Content at Dietspotlight, has researched over 5000 weight-loss programs, pills, shakes and diet plans. Previously, she managed 15 supplement brands, worked with doctors specializing in weight loss and completed coursework in nutrition at Stanford University. full bio.

11 Phytodren Reviews

  • Does it affect drug tests?

    I am a bus driver I want to know if this product will show up bad on a drug test?

    • Anonymous

      Wondering them same thing! I’m in the mines and won’t take it until I know for sure ill pass a drug test

      • john

        this is a great product!

        • Katie

          How long did it take for you to see any results from this product?

    • Angela

      Poppy seed extract is used in opioids. Taking any amount of the accrual extract do have a very negative effect on a drug test. Stir clear.

  • Drug Test

    has anybody been told if itll come up in a drug test as i too work in the mines and i need to know before i start using it?

    • Cameron (Editor)

      Hi, John. We haven’t come across dieters testing positive with Phytodren but it is possible with other similar products. Be sure to carefully inspect the ingredients list.

  •  Will update later
    Marilyn (Verified User)

    Just got started. Will see

    • Maribel (Editor)

      Good luck, Mariyn. Really hope it goes well. If unsure, or unsatisfied…you might also see Dietspotlight Burn. You can sample it too!

  • Tsha

    This product is great for me, it might be working different for other people,last year may I ordered a bottle and I lost 15 pounds in 6weeks I combined with clean eating and a little exercise.then I stopped and maintain my weight till now .

  •  It made me feel bloated !
    M.B. (Verified User)

    I didn’t care for it. It made feel bloated/swollen. Too much money for not only no results but to feel worse.