Updated: 01/16/2018

Serotonin-Plus Review - 6 Things You Need to Know


You may be surprised by what I say in this Serotonin-Plus review. We dug deep and created a detailed evaluation, examining the ingredients, side effects, scientific research and overall customer care. We also focused on hundreds of comments and reviews from around the web. At last, we summed up the data we found to give you the bottom line.

Serotonin-Plus Readers: Click here to find out why we're giving away samples of our product, Burn HD.

What is Serotonin-Plus?

First off, Serotonin-Plus is a weight-loss program for women and men of all ages and body types. It involves weekly visits to the nearest clinic, as well as personalized direction/instructions. Your personal condition is assessed and then you are instructed on how to proceed so you can reach your goals. You are also given a serotonin supplement to take. Robert Posner, M.D. is the licensed physician that acts as the director.

The Serotonin-Plus weight-loss program has been available since 2000. You can learn about the services and purchase products on the official website. We like that there’s some success stories and that the business has been around for years, but read on…

High Cost – “A Concern?”

The first concern was the high price of Serotonin-Plus. “The weight-loss program costs about $100 per week,” said our Research Editor. “Clearly this rate is not affordable for everyone, and could deter dieters from wanting to come back.”

One dieter stated, “It’s just too expensive to keep up with. Not for me!”

“I don’t have the $1,200 they want upfront. This diet is definitely not cheap,” said another person.

Some dieters didn’t mind the cost, considering they noticed results.

“It was the best $1200 I ever spent! After a few months of being out of the program I continue to count calories and keep weight loss/maintenance on my radar daily,” said a customer.

Limited Clinic Locations – “Another Drawback”

While there are Serotonin-Plus clinic locations in 16 different states, this is obviously not ideal for all dieters. One customer commented, “No clinics in my area. I’m definitely not traveling out of state for this diet program.”

Another dieter said, “They need more clinic locations!”

The limited locations of Serotonin-Plus wasn’t a concern for some customers.

“Even though there are no clinics in my area, I ordered it online,” reported a consumer.

Our research has shown if there is a certain facet of a diet program that is especially burdensome, like limited locations, the odds of long-term success are not good. So, if Serotonin-Plus does not offer a local clinic, this could be problematic.

What About The Science Behind Serotonin Plus?

At DietSpotlight, we like to see some documented science that supports the weight-loss product or program in question. In regards to Serotonin-Plus, this is a physician-supervised diet plan, so it is backed by some solid medical research. However, results do vary from person to person and there are no studies on the website.

What Users Are Saying

"Prior to taking this product, I underwent a neuro test about a year ago and the results showed several of my neurotransmitters to be out whack. They were either below or above the normal range limit. After re-doing the same test again earlier this month, they are now all where they’re supposed to be (except for serotonin which is slightly less than where it should to be). I attribute these results, at least in part, to serotonin plus. Along with a combination of other supplements and regular exercise, it has given me greater focus and helped my overall mood and well being."

"It has been 2 weeks, not noticed any difference yet."

"Zero results"

The Bottom Line – Does Serotonin Plus Work?

So, should you try Serotonin-Plus for weight-loss? Well, we appreciate this company’s longevity and we did find some positive comments about it online. But we have some reservations about the high cost of this diet program. Also, we’re concerned about the lack of clinic locations, which makes this system unsuitable for many people.

If you’d like to shed more pounds, we advise you to go with a diet program or supplement that is affordable, does not require regular trips to a clinic and is backed by all sorts of positive customer feedback.

Among the best products we’ve seen this year is one called Dietspotlight Burn. This supplement contains a blend of four key ingredients, which have been shown in documented clinical tests to help accelerate fat loss and ignite metabolism. We can’t locate any talk of harmful side effects and customer comments around the web reveal people are seeing excellent results.

The makers of Dietspotlight Burn are so confident in their product they’re offering a Special Trial Offer, which is very encouraging.

Learn More About Burn HD »
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What are the side effects of Serotonin-Plus?

Because we couldn’t find a list of ingredients, we were not able to give you a list of Serotonin-Plus side effects.

What are the ingredients in Serotonin-Plus?

There was not a clear list of Serotonin-Plus ingredients.

How do I know if Serotonin-Plus is right for me?

Choosing the right product is the #1 question asked by DietSpotlight readers. We recommend trying any product before buying it and know that finding a product with a sample offer is near impossible - so we created our own product, Burn HD, with scientifically backed ingredients.

Click here to get your sample of our powerful fat burner today.

Does Serotonin-Plus work?

Without knowing the list of ingredients, there’s no way for us to determine whether or not science supports any weight-loss claims.

You may want to boot Serotonin-Plus and replace it with Dietspotlight Burn, a supplement that’s made with clinically tested ingredients and shown to help boost metabolism.

How much does Serotonin-Plus cost?

The price of the supplement system ranges from $36.95 for a single bottle to $119.99 for the whole program.

How should I take Serotonin-Plus?

If you look on the label, you should be able to find how to properly take each supplement.

Should I diet or exercise on Serotonin-Plus?
Is the company located in the United States?

Yes, it is located Burke, Virginia.


Previous Serotonin-Plus Review (Updated October 15, 2014):

Serotonin Plus: What You Should Know

Serotonin-Plus is a weight loss program out of Virginia offered for local dieters and dieters who live outside of the state. The program is comprised of 12 weeks of weight loss instruction. The headquarters for the company is located in Virginia, but centers can be found in Pennsylvania, New Jersey, Florida, Maryland and Alabama. Testimonials are available on the website from dieters who have lost weight on the Serotonin-Plus program. There is also a video presentation on the weight loss benefits of oral serotonin. Complete details and contact information can be found on the official Serotonin-Plus website.

List of Ingredients in Serotonin Plus

12 week weight loss program including oral serotonin supplementation.

Serotonin Plus: Product Features

Serotonin is a natural chemical found in the brain and intestinal system in humans. The neurotransmitter performs many functions in the body, but in terms of weight loss, experts believe supplementation can help reduce hunger, carbohydrate cravings and depression. Prescription depression medications are often prescribed by doctors as weight loss drugs.

According to Dr. Robert Posner, when the body is deficient in serotonin, the brain sends out a signal for more. Naturally, the body will try to fulfill the brain's request with food and thus hunger increases and cravings begin. With proper supplementation, the signal for more serotonin will never be sent out and thus hunger is not a problem.

Serotonin-Plus is available for both men and women though research suggests that women tend to be more likely to suffer from serotonin deficiency than men. Testimonials on the website include both men and women, but some of the pictures are grainy with after pictures appearing to include a younger version of the dieter than before pictures.

The Serotonin-Plus supplement is available for sale on the official website. There is no indication that a dieter must sign up for the official 12 week weight loss program in order to take advantage of the supplement. The supplement is priced $36.95 for 120 capsules. Protein bars are also available for sale, as well as high protein shakes. This could mean the Serotonin-Plus program is based on high protein, or an Atkins like approach to weight loss.


  • Complete Serotonin-Plus program details are found online.
  • Supplements can be purchased from the official website.


  • Serotonin-Plus may not increase weight loss.
  • Not all dieters will be deficient in serotonin.
  • The in house clinical program could be very expensive.
  • There is no information about following the program from out of state.

Serotonin Plus: Conclusion

Serotonin-Plus is a physician guided weight loss program with high protein meal replacements. The weight loss claimed by dieters may have nothing to be with serotonin supplementation and everything to do with increasing lean protein in the diet. Before and after photos leave us skeptical about the results.

Summer Banks Dietspotlight Author
About the Author:

Summer Banks, Director of Content at Dietspotlight, has researched over 5000 weight-loss programs, pills, shakes and diet plans. Previously, she managed 15 supplement brands, worked with doctors specializing in weight loss and completed coursework in nutrition at Stanford University. full bio.

12 Serotonin-Plus Reviews

  •  we are interested in your products
    David Abou Khalil

    Hello dear, hope my email finds you well, we have health and beauty clinics in the Lebanese market, and we are interested in your products, kindly advice us how to buy it. Thank you

  • Is this a pill or a drink?

    Is this a pill or drink

    • Stephen (Editor)

      Hey Connie, they come in pill form. Another product that also comes in pill form, that is known to suppress appetite and shed pounds/fat is Dietspotlight Burn. Care to try?

  • N. Bowman

    I have a history of having a hard time losing weight despite apparently doing ‘all the right things’. Fast forward to menopause and suddenly I found myself with a 20 lb weight gain and found it impossible to lose.I have spent my entire adult life practicing moderation, mindful eating, and at times drastic measures to keep myself at a slightly more than I should be weight. With the menopause gain, extreme frustration, self-loathing, and all of those negative side effects of a body that defies ‘normal’ set in. I decided, out of desperation, to seek medical advice. Dr. Posner’s main clinic happens to be 5 mins from where I live so I made an appointment for the same day. Here are my thoughts well into the program: 1) Yes it is expensive. When you are accountable to your own out of pocket it provides an incentive to succeed that is very strong; 2) seeing a doctor for a weekly weigh in and BP check also hold you accountable more than a weight watchers weekly weigh in; 3) that accountability is VERY important; 4) the first week was very hard but I was determined and lost 6 lbs where all previous attempts had failed; 5) Dr. Posner’s primary approach is on a positive attitude for health of both mind and body — I needed that more than anything; 6) when side effects of a primary med he prescribed weren’t positive, he changed my medication and that works much better; 7) I have lost 15 lbs so far and am feeling GREAT; 8) the biggest plus is that I feel I have a LONG TERM LIFELONG approach that I can rely on and I am convinced that I will never gain unwanted weight again; 9) my sense of well being and faith in myself are renewed. Bottom line: IF YOU CAN AFFORD IT, this is an excellent program and if it works for me, it will work for just about anyone. But this is about more than weight loss: it is about a lifelong approach that changes your mindset, not just talks about it, and gives you a coping mechanism in case you find yourself on the gaining track again. I have, therefore, found a sense of peace with myself that is well worth the money spent.

  •  A new you
    London Jones (Verified User)

    I completed my own research on diet program and selected Dr. Posner Serotonin Plus plan. It was the BEST DECISION I’VE MADE in a long time. I feel good, I am healthy, and I have lost 36 pounds so far. According to my FULL BODY SCAN results, 100% of the weight (mass) lost is from fat. I still have 3 full weeks to go and I am very pleased with the results. You meet with him once a week to discuss your progress and what you are eating. If you send him your meal list for the week, he will give advice for change if needed. He also has a forum to share your recipes that work well on the program. Dr. Posner’s plan is forever. Once I complete my 12 weeks, I’ll see him at his office once a month to get my weight recorded. He also has two personal trainers on his staff that facilitates free classes on Saturdays and Sundays. I go to two classes a week and the workouts are tuff but fun. I enjoy meeting the other clients as well. I will join his “A New You” model runway show next year. All patients are welcome to join. A company donate the cloths for you to strut your stuff down the runway show. I attended a show recently but didn’t model in it (too new to the program at the time). There were several Big Wigs of government, the military and the media at the show. More importantly, my boss’s (the president of our company) wife was IN the show. She looked fantastic. She used to be soooo fat and mean. She recognized me and came over to hang out with me. I was shocked. My boss was there as well. Now I am able to leave work for an hour once a week to fulfill my weekly appointments without using vacation or personal time. Four other employees have now joined the program. The appointments just take about 5 minutes but is a long drive from my office. We are working with our HR manager to create a program for employees to afford Dr. Posner’s program. So far we will propose that the company reimburse employees 25% of total cost at the end of the 12 week program if they show proof of completing the program and have lost at least XX% of body weight. we will allow Dr. Posner to determine the appropriate percentage to be fair. He will look at averages and the medium results of he program for similar age groups. My boss will have to approve the proposal, but I don’t think it will be a problem. We have a great deal of hefty people in the office that complain abbot health, having to walk up stair and complaining about the snacks running out of the snack machine. I can’t wait until the next “A New You” show – I am pumped.

  •  Follow South Beach diet
    Shelly (Verified User)

    I did the 12 week program. Its a low card and low fat diet. Is it worth $1,200.00 (NO). I workout everday (burning 1400 cal. a day. I lost 15 pound. You can order the pills online. You need Serotonin Formula 2 pills after breakfast and 2 pills before dinner. Serotonin -plus Multi Vitamin at lunch. Just follow the South Beach Diet w/ less fat and you got it. Also get a scale the weights water, fat, and muscle all this for 200.00 dollars. 🙂

    • Jane

      Shelly, can you tell me which site I could order from? Thanks.

  • I would like to order
    Kimberly Lichtenberg

    I would like to order the Seratonin supplement. How do I do this?

    • Maribel (Editor)

      Can’t order here, Kimberly. We’re not really part of the company. However, you may want to sample Dietspotlight Burn. A great and affordable product for weight-loss and improving your metabolism.

  •  seratonin
    C. Worley (Verified User)

    I did the 12-weeks on seratonin plus, and I lost 33 pounds. It is a good program. The eating plan is basically low carb (similar to South Beach); but I believe that the supplements helped. I also did MORE exercise than the average participant, but I’m not sure I would have had the energy/motivation to do the exercise without the supplements. I think they really helped a lot. (48-year-old woman with three grown kids).
    – C.

    • London Jones

      @ C. Worley – I agree with you. It is a great program. I have 3 weeks left on the program and have lost 36 pounds so far. How are you doing with your progress? Do you still go to his office to get your weight?

      • E. Hodge

        London jones: I do not have a clinic anywhere near me. My nutrition is great I already eat low carb low fat but having an extremely hard time losing. I just keep gaining!! Do you feel like the supplements are enough to help me? Thanks e. Hodge