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Synbiotic 365 Review - 11 Things You Need to Know

Time to reduce that bloat and fight those cravings with Synbiotic 365. The power of a healthy gut extends to the entire body, so Synbiotic 365 claims it will help promote a healthier gut – easy, right?

Our researchers wanted to know if this was the entire story or if there was more to it than the simple claim of a healthier digestive tract. They dug into the ingredients, possible side effects and what else the company has to offer.

Synbiotic 365 can be purchased through their Official Site.

Synbiotic 365 Readers: Noom is offering our readers a 14-day trial, for a limited time. Click here for this special offer!

What is Synbiotic 365?

Synbiotic 365 is a 3 in 1 probiotic (or synbiotic). This advanced probiotic formula is supposed to help refresh the gut flora that’s keeping your digestive health on track. Poor eating habits, environmental factors and habits like smoking can kill off healthy gut bacteria. Probiotics have been the replacement tool of choice for years, so what makes Synbiotic 365 different?

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What Company Makes Synbiotic 365?

The company behind Synbiotic 365 is United Naturals. There is an official website and you can order directly from the company. 

United Naturals operates headquarters in both the United States (US) and Canada. 

  • US Headquarters: 1300 Altura Rd, For Mill, SC 29708
  • Canadian Headquarters: 1790 Rue Du Canal St 401, Montreal QC, H3K 3E6

The customer service phone number is 1-844-794-7728 – for both the US and Canada.

Synbiotic 365 Customer Testimonials

The Company and the Better Business Bureau (BBB)

There are multiple United Naturals business listings on the BBB website. 

The BBB listing with the most reviews shows the company is not accredited or rated. However, an average of 68 customer reviews give it an almost 5 star rating.


Synbiotic 365 Claims

Synbiotic 365 claims to be an advanced probiotic formula. It also claims to:

  • Help fight food cravings.
  • Relieves bloat.
  • Relieves other embarrassing digestive issues (not specified).

Synbiotic 365 Ingredients

The ingredients in Synbiotic 365 are:

  • Probiotic Blend: 20 Billion CFU
  • Chicory Root Inulin
  • Thiamin
  • Riboflavin
  • Niacin
  • Folate
  • Vitamin B12
  • Biotin
  • Pantothenic Acid

Details on Synbiotic 365 Probiotic Ingredients

The only ingredients worth anything, in terms of probiotics, are:

Probiotic Blend: 20 Billion CFU – There is a bit of proof showing that probiotics can help with weight loss. One study in Nutrition & Metabolism claims, “Probiotics have physiologic functions that contribute to the health of gut microbiota, can affect food intake and appetite, body weight and composition and metabolic functions.” 

A study in the journal Nutrients doesn’t fully support these results. According to the journal, “Further studies are needed before probiotics can be rationally prescribed for the prevention or treatment of obesity.” 

Chicory Root Inulin – Inulin is added to Synbiotic 365 as a source of fiber. The root is commonly used in cereals, breads and other foods to increase fiber content. Fiber may help reduce hunger so that it could be an excellent addition to your meal plan or supplementation. 

A study in the journal Genome Biology claims healthy gut bacteria may reduce visceral (often abdominal) fat stores. Fiber supports gut bacterial growth and health – so you see the possible connection to weight loss. 

How to Take Synbiotic 365

There are 30 capsules per box with Synbiotic 365. The serving size is one capsule daily, based on what we could find. There’s no direct information from the company or on the official website that explains exactly how it is taken. If you’re supposed to take multiple each day, that will reduce the length of time the bottle will last. 

  • One capsule a day: 30 days
  • Two capsules a day: 15 days
  • Three capsules a day: 10 days
  • Four capsules a day: about seven days

Benefits and Results of Synbiotic 365

There are no proven benefits or results, in terms of weight loss, for Synbiotic 365. Customer reviews are non-existent because the only place to purchase the probiotic supplement is on the official website. We even checked review websites to see if there were any comments there and found nothing.

Cost and Where to Buy

You purchase Synbiotic 365 directly from United Naturals. The prices are:

  • One box: $45 
  • Three Boxes: $119 ($39.67 per box)
  • Six Boxes: $229 ($38.17 per box)

Even though some search results show Amazon as a Synbiotic 365 retailer, our research showed no listings on Amazon at this time and no old listings with information still available on the site.

Side Effects

Synbiotic 365 Side Effects

The side effects of probiotics and prebiotics are simple – gas and bloating. Even though this supplement claims to fight bloating, the fact is some people who take products like Synbiotic 365 experience gas and bloating. This is especially true when probiotics are first started. Over time the side effect may fade, but not in all cases.

  • Gas
  • Bloating
  • Diarrhea
  • Constipation
  • Loss of Hunger
Pros and Cons

Pros and Cons

What’s the final take on Synbiotic 365? There are good and not so great things about the company and the product, but all-in-all there’s nothing supremely negative to speak of.


  • Can be purchased online. 
  • Covered by a money-back guarantee. 
  • Possible digestive and immune support.
  • Contains 12 probiotic strains and eight essential vitamins.


  • Priced higher than other probiotic/prebiotic/synbiotic supplements.
  • Not available on trusted retail websites like Amazon.
  • No customer reviews found.
Synbiotic 365 Ingredients
Bottom Line

Bottom Line on Synbiotic 365

We’re just not sold on Synbiotic 365. We’re not sure why the probiotic is so expensive or why the company isn’t using Amazon as a sales platform. Potential customers are looking for current and previous customers to see what they can really expect from a supplement. Without those reviews, the customer is supposed to settle for two paragraphs of information and an ingredient list to make a decision.

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Synbiotic 365 Review
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Synbiotic 365

What are the side effects of Synbiotic 365?

The potential side effects of using Synbiotic 365 include gas, bloating, diarrhea, constipation and loss of hunger.

What are the ingredients in Synbiotic 365?

The primary ingredients in Synbiotic 365 are probiotic blend and chicory root inulin.

Does Synbiotic 365 work?

When speaking of weight loss, the ingredients in Synbiotic 365 are not proven effective.

Did you find any Synbiotic 365 product warnings?

Speak with your physician before taking Synbiotic 365 if you have questions about whether or not the formula is safe for you.

Where can you buy Synbiotic 365?

To purchase Synbiotic 365, you’ll need to visit the United Naturals website.

Where can I buy Synbiotic 365?

Synbiotic 365 can be purchased using their Official Site.

How should I take Synbiotic 365?

Each bottle contains 30 capsules – so it’s easy to assume you take one daily. The fact is, without that information, the user doesn’t know how much to take.

Are there any free trials or samples of Synbiotic 365?

There are no free trials or samples of Synbiotic 365. 

Is there a money-back guarantee for Synbiotic 365?

“All refund requests must be within sixty (60) days of the date your credit or debit card was charged.” You can send back up to two empty containers.

9 Synbiotic 365 Reviews

  • Sherri (Verified Purchase)

    I’m not 100 percent happy. No weight loss , sick to my stomach feeling, conspitation.

  • Michelle (Verified Purchase)

    Great research! I’ve been taking one a day for a week and implemented a gluten few dirty! Feeling pretty good

  • Organic or not

    You proclaim it is organic but I do not see a USDA symbol on your package

    • Montana (Editor)

      According the Synbiotic 365 official website, their product isn’t organic, but their package is recyclable.

  • Synbiotic 365 is a GREAT PRODUCT
    Katheryn (Verified Purchase)

    I use Synbiotic365. On the 2nd box. My gut feels much better and I am down over 10 pounds. It is very much worth the price.

  • Jodie

    They sell this on ebay. What is the difference between the editions. They have edition v, edition 3 and edition 5?

  • Yes, try it!!
    Betty Ann Axline

    I just started this product today, we’ll see in. Thirty days!!!

  • Awesome product!!!!
    Michael k Rollins (Verified Purchase)

    Iam taking it everyday
    And it simply makes me
    Feel better with more energy!!!
    Aloha god bless from Maui
    Michael k Rollins

  • Available other than United Naturals

    You can purchase this on e-bay for significantly less. But still not available on Amazon.