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Xenadrine Next Gen Review - 9 Things You Need to Know

Xenadrine Next Gen is “powerful,” or so the description says made with a patented pill design. When our research team stumbles on words like that, there’s no doubt they’ll jump right in to see if the ingredients support the claims, if science backs the formula, and if the formula may work as claimed. Let’s take a look at what we found after hours of research.

Xenadrine Next Gen can be purchased through their Official Site.

Xenadrine Next Gen Readers: Noom is offering our readers a 14-day trial, for a limited time. Click here for this special offer!

What is Xenadrine Next Gen?

Xenadrine Next Gen is essentially a fat burner that comes as a 60-count supplement, but the manufacturer also claims it can positively affect energy and focus, as well. The neuro, or focus, products were all the rage before keto started, but now making such a claim doesn’t hold the weight it once did.

The marketing behind the Xenadrine Next Gen dietary supplement is pretty good. Word choices like nano bead science, neurosensory, scientifically dosed, unique, and trusted are just a few that Xenadrine hopes will lure in the reader and convince them to make the buy.

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Who’s Behind the Weight-Loss Formula?

The company behind the supplement is Xenadrine. This isn’t the only product the company sells, but it is one of the newer products available. The design uses advanced dual capsule technology. This type of delivery system is typically used to extend the time the supplement works. For instance, after the stomach dissolves the first capsule and the ingredients enter the intestine to be absorbed, the second capsule starts the same process – thus the extended release.

Where Xenadrine dropped the ball is with customer support. We read every page on the official website and found no contact information, customer service phone number, or even an email address.

But, if you take a few minutes to read the entire Privacy Policy, the very last paragraph lists an address in Canada people can use to contact the company.

381 North Service Rd. West
Oakville, ON Canada L6M 0H4

Xenadrine Next Gen Customer Testimonials

What are the Xenadrine Next Gen Ingredients?

The Xenadrine Next Gen supplement facts label is a little confusing at first because the company has chosen to list the B vitamins in the formula. B vitamins are often explained as energy boosters, but that’s an exaggeration. The body uses B vitamins in the production of energy, but taking more than the body can use in a short time means the remaining vitamin is passed out during urination.

The active ingredients in the weight-loss supplement are:

  • Medium Chain Triglyceride Oil
  • Clarinol
  • Robusta Coffee Bean
  • Caffeine Anhydrous
  • Longan Extract
  • Nutmeg
  • Theacrine
  • Rhodiola Extract

Other inactive ingredients are gelatin, titanium dioxide, microcrystalline cellulose, dicalcium phosphate, stearic acid, magnesium stearate, and silicon dioxide.

Ingredient Details

Ingredient Details

Medium Chain Triglyceride Oil (MCT)

MCT is quite popular in the world of keto and paleo. The oil increases fat intake, which helps with ketosis and weight loss. But, in Xenadrine Next Gen, which was not developed for a high-fat diet, does have a history of research showing a possible positive effect on weight loss. In The Journal of Nutrition, a literature review of MCT oil showed, “MCT increase[s] energy expenditure, [and] may result in faster satiety and facilitate weight control.”


Clarinol is a brand of conjugated linoleic acid (CLA). The information on CLA has been twisted and contorted so badly over the years that it’s hard to discern what’s true and what’s not. The official website for the brand lists five studies, all completed in 2011 or earlier, so there’s a gap in research. Some factors that leave us questioning the research include:

  • The analysis was completed on CLA, not Clarinol.
  • Long-term (six to 12 months, or longer) use of high doses (3000 to 4000 mg per day) was part of several studies.
  • There’s more talk about changes in body fat mass than weight.
  • The most recent study in the European Journal of Nutrition claims CLA doesn’t appear to aid weight loss. “The evidence from RCTs (randomized controlled studies) does not convincingly show that CLA intake generates any clinically relevant effects on body composition on the long term.”

Robusta Coffee Bean

Robusta coffee bean comes from the same plant as Arabica coffee beans, which many people use to brew coffee. The major difference between the two is Robusta contains nearly two times the caffeine of Arabica.

Caffeine Anhydrous

Caffeine, the most widely used drug in the world, works on the central nervous system to increase energy and focus. In some cases, at high enough doses, side effects may appear to benefit. For instance, large amounts of caffeine intake can cause nausea, but to a dieter that may feel like the loss of appetite or suppressed hunger, as promised.

Longan Extract

There is no clinically significant connection between longan fruit and weight loss. We did find a rat study from 2010 that showed reduced weight gain in rats fed hypercaloric (excessive calories) diets.


Nutmeg is a spice commonly used in baking. There are claims that it can reduce pain, improve digestion, and even help with bad breath, but we were unable to find a sliver of evidence to support any of these claims.

Theacrine (Teacrine)

Theacrine is similar in structure to caffeine, which would account for the addition to Xenadrine Next Gen.

Rhodiola Extract

According to the National Center for Complementary and Integrative Health, Rhodiola extract is commonly used to improve stamina, energy, and memory, among other benefits. However, the National Center goes on to say the studies used to support the claims are not powerful enough to be significant.

Possible Side Effects

Any Side Effects With Xenadrine Next Gen?

No, Xenadrine Next Gen doesn’t cause any side effects. No supplement causes side effects. It’s the ingredients in the supplement that cause issues with some users. That’s why companies can claim their supplement is free of side effects.

Based on the ingredients in the formula, the only side effect we’d imagine to be commonly reported would be associated with the caffeine. Too much caffeine, as measured based on a person’s tolerance, can leave you feeling:

  • Shaky
  • Jittery
  • Nauseous
  • Angry

Does Xenadrine Next Gen Work?

Each ingredient in Xenadrine Next Gen offers a benefit, of some sort. That benefit, in most cases, has nothing to do with weight loss and more often deals with more traditional health concerns like energy or irritable mood.

The best ingredient this product has going for it is the caffeine, but there is some hope for longan extract and theacrine with further unbiased research.

Where to Buy

Where Can You Buy Xenadrine Next Gen and Cost

Xenadrine is one of many companies that have a standing relationship with major retailers like Walmart, Amazon, and Walgreens. We’ve also seen the supplement available on eBay and other auction websites. You can expect to pay somewhere around $20 per bottle.

Pros and Cons


  • The price is lower than many competitors.
  • Xenadrine has been around for decades.


  • The ingredients are commonly used.
  • May cause side effects, like irritability and excessive energy.
What Users Are Saying

What Users Are Saying

“I was a little skeptical when I tried these for the first time. I was afraid they would make me feel like I had too much caffeine but used as directed, these diet pills are the best I’ve ever tried. I have lost 40lbs and I don’t have any side effects from them. I am extremely pleased.”

“It made me jittery, but didn’t provide energy or appetite suppression.”

“I used to take Xenadrine years ago and felt a great energy boost and lost 50lbs! So I decided to try it again, and nothing! No energy, no pumped feeling! What happened to the Xenadrine I used to love?”

Xenadrine Next Gen Ingredients
Bottom Line

Bottom Line on Xenadrine Next Gen

At the end of the day, you’re looking for a supplement to help you stick with your weight-loss goals. A product that can help cut back appetite and give you a little energy boost. Making long lists of claims and using big words, like Xenadrine Next Gen, don’t make the product any more effective.

We’re all for using supplements to promote weight loss, but we believe lifestyle changes are a powerful tool that can help you keep the weight off for good.

Among the best of the best in weight-loss apps is Noom. Amazing changes come with this new version of the app, including human coaching, customized meal plans, an extensive food database, food logging, exercise tracking and more.

We also love that Noom is offering our readers access to a 14-day trial for a limited time.

Learn More About Noom »
Xenadrine Next Gen Review
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Is Xenadrine Next Gen for weight loss?

Xenadrine Next Gen is a fat burner supplement meant to aid in weight loss.

What are Xenadrine Next Gen ingredients?

Xenadrine Next Gen ingredients include MCT oil, robusta coffee bean extract, caffeine anhydrous, Yohimbe extract, Bioperine black pepper extract, Satsuma mandarin pulp, niacin, Huperzine-A, and vitamins B1, B2, B6, and B12.

Are there any Xenadrine Next Gen side effects to worry about?

Due to the caffeine content in Xenadrine Next Gen, potential side effects may include nausea, anxiety, jitteriness, and shakiness.

Is Xenadrine Next Gen safe?

Although Xenadrine Next Gen is safe to use, make sure to consult with your medical doctor before using any weight loss supplement.

Is Xenadrine Next Gen for men or women?

Xenadrine Next Gen is a fat burner made for anyone 18 or older.

Where can I buy Xenadrine Next Gen?

Xenadrine Next Gen can be purchased using their Official Site.

Is there a Xenadrine Next Gen free trial or sample?

There are no free trials or samples of Xenadrine Next Gen.

What is the most common complaint of Xenadrine Next Gen?

The most common complaint of Xenadrine Next Gen are the side effects from the high caffeine content.

What are some products similar to Xenadrine Next Gen?

Similar products to Xenadrine Next Gen include Burn Bullets, Abdominal Cuts, and Cellucor Super HD.

Xenadrine Next Gen Reviews