Updated: 04/18/2017 - Site operated by Leptigen
By Summer Banks Mar 24, 2017

We’re hearing a lot of buzz about Zantrex 3, so we focused our attention on ingredients, side effects, customer service and scientific research. Furthermore, we scrutinized hundreds of consumer reviews and comments. We then detailed and summarized to give you the info you need.

Zantrex 3 Readers: Click here to find out why we're giving away samples of our product, Leptigen.

What is Zantrex 3?

To begin with, Zantrex 3 fat burner is a supplement containing yerba mate, guarana, trimethylxanthine, damiana, green tea, kola, schizonepeta, black pepper, rhodiola crenulata, Asian ginseng, maca, cacao and black tea. The recommended serving size is two capsules prior to meals to supposedly assist with weight-loss. One of the benefits of the product is the ease of use.

The product, introduced more than 20 years ago by Zoller Laboratories/Basic Research, doesn’t appear to use synthetic ingredients, a good decision. You can buy the supplement on the official website and through trusted retailers. We do like the length of time the company has been in business and the money-back guarantee, but read on…

Zantrex 3 Side Effects – “Leaves You Shaky?”

The first concern we had was Zantrex 3 side effects. “Several fat burners contain caffeine-style ingredients,” said our Research Editor. “But when formulas contain additional thermogenics, there is a chance of adverse reactions.”

“After using Zantrex-3 the second day, within 15 minutes after taking this supplement, my face felt as though it was on fire and was getting more red by the minute. As I glanced at my arms and hands, they too were turning red,” said one user.

“I have been taking it for a week and have never felt so sick in my life. I started with one pill twice a day and bumped it up to two twice a day. Didn’t make a difference. I feel so sick every time I eat. Dizzy, nauseous, headaches,” offered a dieter.

FDA Judgments – “A Concern?”

In January of 2005, Basic Research was contacted by the Food and Drug Administration about the mislabeling of supplements. According to the complaint, products were claimed to affect “the structure or function of the body.” This is not allowed under current laws. The statements have since been removed.

Ineffectiveness – “Just Doesn’t Work”

In our review, the consensus was the Zantrex 3 ingredients were ineffective. “Unfortunately, this did energize me, but didn’t help me lose anything. 1 bottle down and drum roll please…..I have gained 3lbs,” reported one customer.

“Used this with no results a few years back. Very disappointing! I exercised faithfully as well,” said a consumer.

“This product didn’t do anything for me. I eat a lean diet and exercise 6 days a week. I noticed no difference,” offered a user.

Our research has shown that if a portion of a weight-loss system is a concern, such as effectiveness, there’s a chance you will not notice success in the long-term. If Zantrex 3 is ineffective, that could be a problem.

The Science – “Legit Ingredients?”

The official Zantrex 3 website states user’s experienced “546% more weight loss,” but we can’t locate clinical trials to that effect. There’s no trouble finding research into green tea or caffeine, but you’ll also find supplements with these ingredients by the thousands. At DietSpotlight, finding science backing claims is critical. If a company can’t provide support, we have concerns.

The Bottom Line – Does Zantrex 3 Work?

So, we’ve reached the end of the road with this one and what’s the final take? There are positives, like a few favorable customer comments and the fact that the company has a strong foothold in the industry, but have reservations recommending it because of the lack of scientific research supporting weight-loss claims. Plus, we’re concerned about FDA judgments against the business and several complaints posted on ripoffreport.com.

If you’d like a complete body turnaround, we suggest going with a product that’s both cost effective and clinically proven that’s had no negative interaction with the Food and Drug Administration.

Among the best products we’ve seen this year is our supplement called Leptigen. The formula contains a four-ingredient blend, clinically-tested with results often found in studies such as The American Journal of Clinical Nutrition.

Also, we’re so confident that you’ll love our supplement, that we’re offering a Special Trial Offer, which is a great sign.

Previous Zantrex 3 Review (Updated July 16, 2014):

What You Should Know

The Zantrex 3 product is manufactured by Zoller Laboratories. This company prides itself on the fact that the item does not contain Ephedrine. Unfortunately, the official website for the product does not have much information. A person may be able to rely on third party website for more facts about Zoller Laboratories. They do have an official website, however. An individual can explore the Zantrex 3 product as well as purchasing information. The site offers information about the product in a sales pitch format, but detailed information is not present. A potential customer can also view a video of the type of benefits that Zantrex 3 can offer an individual looking to lose weight. The company claims that both men and women can receive substantial benefits from this product.

List of Ingredients

The official website does not offer a list of ingredients for review. Nevertheless, a third party site listed all the ingredients in Zantrex 3. These are: Green Tea Extract, Damiana, Schizonepeta, Tibetan and Panax Ginseng, Maca Root, Kola Nut.

Product Features

The manufacturers of Zantrex 3 claim that their diet tablet is designed for large amounts of weight loss, extreme energy and increased stamina. They also state that their product is the best on the market because they go well beyond a fat burner stimulant. The manufacturers of Zantrex 3 insist that their merchandise will assist a person in gaining more energy for exercise as well as acting as a rapid weight loss tool. An individual can purchase this product directly from the official website, an online retailer or from a local store. The cost of the product for 84 capsules is around $50.


  • An individual can purchase the Zantrex 3 product from the official website.
  • A person can view some information about the item, watch a video and learn a little bit about the company.
  • Several locations are available for purchasing this item. A savvy shopper could find some cheaper prices this way.
  • The components found in Zantrex 3 are natural.


  • Detailed information about the product or the company cannot be found on their official website.
  • They do not have a list of ingredients presented on their official site either.
  • The product is fairly expensive.
  • A large amount of caffeine is found in the ingredients of the Zantrex 3 tablets.


The Zantrex 3 product sounds great in theory. Nevertheless, when a diet supplement contains large amounts of caffeine we always get a bit weary, since caffeine has been linked to various negative health effects. The Zantrex 3 Side Effects touches on this. The official Zantrex 3 website is designed more as a sales pitch and a purchasing tool than as an informative web presence. A person may need to locate a third party website for a complete guide to the Zantrex 3 product. An explanation of ingredients, testimonials or benefits may also be found at these locations, but we'd like to see more about Zantrex 3 from the manufacturer's themselves!

Zantrex 3 Questions & Answers:

We summarized hundreds of user comments about Zantrex 3 into this helpful FAQ.

What are the side effects of Zantrex 3?

Some potential side effects of Zantrex 3 are flushing of the skin, rapid heartbeat, sleeplessness, irritability, nervousness, upset stomach and nausea.

What are the ingredients in Zantrex 3?

The ingredients in Zantrex 3 are yerba mate, guarana, trimethylxanthine, damiana, green tea, kola, schizonepeta, black pepper, rhodiola crenulata, Asian ginseng, maca, cacao, black tea, gelatin, magnesium stearate, stearic acid, rice flour, microcrystalline cellulose, silicon dioxide, titanium dioxide and fd&c blue #1.

Does Zantrex 3 work?

Although the company claims Zantrex 3 is supported by research, there’s no evidence the supplement is effective. You may want to think about changing things up a bit and substituting Zantrex 3 for a supplement like Leptigen, which consists of a formula clinically proven to work.

How much does Zantrex 3 cost?

One bottle of Zantrex 3 costs $39.99.

How should I take Zantrex 3?

You should take one serving, two capsules, three times per day prior to meals. The company recommends not exceeding six pills within a day. If you take as directed, one bottle lasts 14 days.

Can I take Zantrex 3 if I have a health condition?

Those under 18 years of age, anyone taking prescription medication, those with health conditions, women who are pregnant or nursing should consult with a healthcare provider prior to using weight-loss supplements, including Zantrex 3.

What do users like about Zantrex 3?

Some users liked that the small size of Zantrex 3 makes it easy to use and that the official website sells the supplement.

What do users NOT like about Zantrex 3?

We found that dieters didn’t like the side effects linked to Zantrex 3 and that the supplement isn’t as effective as claimed.

How do I contact the Zantrex 3 customer service department?

You can contact the Zantrex 3 customer service department by calling 1-800-898-5153, using the customer feedback form or by mailing correspondence to the corporate headquarters at Zoller Laboratories 5742 W. Harold Gatty Dr. Salt Lake City, UT 84416.

Do I need to diet on Zantrex 3?

No, you don’t need to diet on Zantrex 3, but eating healthy meals is beneficial to achieving weight-loss goals.

Do I need to exercise on Zantrex 3?

No, you don’t need to exercise on Zantrex 3, but the company recommends adding fitness to maximize your weight-loss.

Does Zantrex 3 come with a guarantee?

Yes, Zantrex 3 comes with a guarantee. If you are unsatisfied with the product for any reason, you can return the supplement for a full refund within 30 days.

Do you know of any special deals or discounts on Zantrex 3?

There’s no mention of special deals or discounts on Zantrex 3. However, our month has been bananas with our readers taking advantage of Leptigen’s Special Trial Offer, which is just the cost of shipping and handling. Click here to give it a go.

Zantrex 3 Side Effects:

After hearing numerous dieters asking about potential problems with Zantrex 3 we decided to take a close look at Zantrex 3 side effects. The ingredients and clinical research were part of our research. We read hundreds of experiences, picking through the comments for facts. Then, we took all that information and condensed it to give you the bottom line.

What You Need to Know

First off, Zantrex 3 is a fat burner with guarana seed, yerba mate, trimethylxanthine (caffeine), green tea leaf, kola seed and more. You are supposed to take two capsules 15 minutes before each meal. The company claims this will boost weight-loss. You can choose to take a couple with you or throw the whole bottle into your bag.

The product, offered up by Zoller Laboratories, is made from all-natural ingredients, always something to look up to. The supplement is available through various websites and in stores. We like that the company has been in the business for more than 10 years and there is a strong BBB rating, but read on…

Headaches – “Ouch!”

The first problem we found mentioned with Zantrex 3 side effects was headaches. “If there is a consistent report found multiple times from different dieters, you need to take that into consideration,” says our Research Editor. “In the case of Zantrex 3, pain appears to be an issue.”

“Dizzy, nauseous, headaches…this isn’t worth it. I feel like total garbage. And I tried to work out today and felt like I was going to pass out when I finished,” said a dieter.

“Ive noticed that its been giving me a really hard time to sleep and sum really bad headaches! is this normal?,” claims another.

The same issue came up time and again, “I had this ghosting headache and felt just odd in general (not to mention that I could never get to sleep).”

Increased Heart Rate

We also found multiple dieters talking about increased heart rate. “It made my heart rate so fast and rapid it was dangerously fast,” one user explains.

Another experiences the same, “Racing heart, vomiting, excessive energy. Not recommended.”

Somehow for some there was also fatigue, “Somehow the confluence of ‘extracts’ produced both heart-pounding jitteriness, as well as an ‘out of it,’ dazed sense of malaise.”

The Science

We looked for research into Zantrex 3 but the only study we found did not have a link so dieters can’t read the complete report. When we looked for clinical support, we found the opposite. A study published in the Journal of Dietary Supplements reported some rather bad side effects. Then, “after discontinuation of Zantrex – 3, the patient experienced no further [side effects].” We need science at DietSpotlight. Without that we can’t see a reason to give the product a try.

The Bottom Line

Our look at Zantrex 3 side effects was quite interesting. We found positives, like a strong BBB rating and some supportive customer reviews, but we can’t recommend a supplement that is not clinically proven. We’re also concerned by the headaches, jitters and increased heart rate reported by dieters using the formula.

If you’re at the point you want to lose more weight, our suggestion is to try out a supplement that’s backed by clinical research to help you lose more without the risk of side effects.

Among the best supplements we’ve encountered in 2016 is Leptigen. This product comes with a proprietary blend of four ingredients shown in published clinical research to help boost metabolism and spark fat loss. We searched high and low for reports of harmful side effects and found none. What we did locate were some dieter comments offering details about amazing results.

Plus, the company that makes Leptigen is confident in the supplement, so they’re offering a Special Trial Offer, a good sign.

We dug deep into the Zantrex 3 ingredients in order to provide you with the important facts and details.

Yerba Mate

Yerba mate is a plant that grows in countries such as Argentina, Paraguay and Brazil. It has been used in medicine to treat constipation, diabetes, depression, urinary tract infections and fatigue. Furthermore, it’s found in a number of energy drinks and diet supplements for weight-loss.

What is it Supposed to Do?

Yerba mate contains caffeine, which is a stimulant that boosts energy levels, improves focus, reduces fatigue and may help increase metabolism. Therefore this herb may assist with calorie burning.

Clinical Research

While this herb does contain some caffeine to improve focus, according to the Mayo Clinic, “Proponents of yerba mate say that it can relieve fatigue, promote weight loss, ease depression, and help treat headaches and various other conditions. There’s no definitive evidence that these claims are valid.”

Clinical research is an important part of the equation when it comes to choosing a diet supplement. Therefore, we recommend that you take a look at a product like Leptigen. It contains powerful ingredients that are backed by actual science.


This is a stimulant and mild diuretic that comes from natural sources such as tea leaves, coffee seeds, guarana and yerba mate plants. It’s commonly found in energy drinks, teas, coffee beverages, chocolate and many diet pills.

What is it Supposed to Do?

Caffeine is a stimulant that affects the central nervous system. It has been shown to boost energy levels, reduce fatigue, improve concentration and even stimulate metabolism. It’s often used in weight-loss supplements to reduce appetite and increase calorie burning.

Clinical Research

There is some research that supports the effects of caffeine for weight-loss. For instance, MedicinePlus.gov says, “Caffeine has many effects on the body’s metabolism, including stimulating the central nervous system. This can make you more alert and give you a boost of energy.”


Guarana is a plant that grows in regions like Brazil. It’s also known as Paullinia cupana or Brazilian cocoa. This plant is sometimes used to treat anxiety, headache, poor mental performance, malaria, diarrhea and joint pains.

What is it Supposed to Do?

Like kola nut, yerba mate and coffee seeds, guarana contains caffeine. This stimulant may help with weight reduction by elevating metabolism and reducing hunger. This is why it’s used in many over-the-counter diet products.

Clinical Research

According to WebMD, “There’s some evidence that guarana – when used along with other supplements – may promote weight-loss. It’s uncertain if the guarana specifically was responsible. Because caffeine is a stimulant that has been shown to improve mood and aid weight-loss, guarana may very well also have these effects.”

Is There Anything Out There That We Think TRULY Works?

We did find one supplement that hits the mark. Leptigen is formulated with key ingredients that HAVE been clinically tested. Be aware that all customers can take advantage of a Special Trial Offer, currently available. Click here to give it a shot.

Get Your Sample Today »
Dietspotlight Author
About the Author:

Summer Banks, a content strategist at Leptigen, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 3.6. From 228 votes.
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User Comments (188)


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How old do you have to be to use this product. Sixteen? Thirteen? Twenty?

Hi! For detailed product information and age requirements, please refer to the Zantrex official website for more information.


I’ve read reviews that say side effects of Zantrex are skin turning red and itchy.
That sounds like side effects of taking Niacin, B-3.
If Zantrex has Niacin in a dose of 100mg or larger? You need to eat something first before taking the dose.


I don’t know why as soon as I take the pill I get red All over fire arms neck face. Don’t know why ?

Cameron (Editor)

You can be experiencing an allergic reaction to one or more of the ingredients in the formula. Seek immediate medical attention from your doctor. Also consider speaking to a specialized allergist who can assess what ingredients might be causing these effect on you, Melanie. Hope this can help!


I took Zantrex 3.blue bottle yesterday at 3pm I TOOK 2 WITH A MEAL it is now the next day 739am and I haven’t slept my heart has been racing I threw up several times I had diarrhea sweats headaches anxiety and I missed work and I think I’m going to miss work today to
…. how long till this stops when does it come out my system I just want to sleep and feel better

Stephen (Editor)

Hey, Jessica. If the discomfort doesn’t subside in the next few hours or day please contact your doctor or medical attention.


I started the blue bottle today..i use to take them about 6 years ago when losing weight for my wedding and they worked me…anyway i started back today. I took 2 this morning with a bottle of and i felt horrible…maybe because i did not eat a full meal…but i felt jittery, nauseated hot flashes and i had a horrible headache. I drunk some gatorade and rested. I now feel better but tomorrow i will start with one pill for breakfast…I’ll keep y’all posted


I definitely did not expect the side effects to be really bad. I’m shaking, I feel somewhat dizzy. Is 2:07 am and I can not sleep!!!!! Its driving me crazy, but then again its my first day…. so ill have to see what happens next :/


Does it really work, I try my first skinnystix (power for water ) today and have no energy from it. Does it affect my thyroid , I’m trying to lose weight . Please contact me. Thanks

Hello Staci, please consult with your physician in order to respond to your question. Only your doctor could adequately advise you in such a specific case; it’s important to ask your doctor before taking any supplement.

Your Name

Why do I itch when I take the blue bottle pills of zantrex

Hello, some clients experience different side effects. Please consult your physician to select the right product for you.


Does skinny Stix fusion show up dirty for a drug text

Hello, please check the exact ingredients please refer to the Zantrex 3 official website and then consult your physician.

Nikki S

I have been on the red bottle for 4 days now and I have lost 7 pounds… I didn’t eat with my pills the only time I ever felt shaky or jittery and I have tons more energy. However u need to drink lots of water and do not take after 5 or u will not sleep


I want to know where can I get zantrex 3 in cape town

Hello Bevern, for product ordering inquiries or sales locations, please refer to the Zantrex 3 official website for more information.


I take the capsule stuff. I was just curious do I have to take it 15-30 minutes before eating? There are times that I would get so busy doing something that I would forget that I didn’t eat anything all day. So, I just wanna know if that is safe or if I should make sure to take it and not forget only to remember like 6 hours later or something.

Hi Kitten, for detailed product instructions please refer to the official Zantrex 3 website.


Alice, I’ve been having the exact same issue and affect with it. I am allergic to sulfa and haven’t seen anything on the bottle telling me it had sulfa in it. I take it twice a day, but I only have the reaction maybe once every other day or so. So I thought maybe it was what I was eating with it, or like maybe I wasn’t eating enough with it. I’m a little lost and just looking for a good fat burner.

adria franco

Does the Zantrex skinny Sticks for water does it work ??


Ive been taking it for a 2 weeks loss 5lbs really dont get hingry much but i also drink alot of water with it and after.


My son is 11 years old and weighs 224lbs is there a safe dosage for him

Hello Judy, the majority of the Zantrex 3 product line is not intended for anyone under the age of 18. Please consult with your doctor before any minor takes this product.


Just started z3 blue bottle yesterday !!!! Im 25 yrs old married with 4 kids and weigh 216 :'(
Im excited to try this tho and hope it works .today is me secound day !!! Wish me luck..btw taking 4 a day 2 at 10 and 2 b4 5

Your Name

I didn’t like the blue zantrex bottle. I found the zantrex 3 red bottle more effective.


just got the blue bottle today..hope it works,


I hate to ask..but does anyone know if it causes constipation…


I’ve tried the blue bottle which did not work for me i actually became extremely sick from the blue bottle but use the red bootle which works amazing for me and gives me a great energy boost for a great work out but every one has different reactions to things i would find it odd that it would make you constipated because thats a way of losing the weight but maybe add some flax seed to your diet that should help loosen your stole

Hello, some clients experience different side effects. If it gets worse, please consult your physician.


will this count as a steroid or just a supplament like weigh protien shakes

Hello Ian, Zantrex 3 fat burner is a supplement.

Related Web Page

I have started using my Eliptical 30 minutes a day everyday. I have not chaged my diet. Will I still loose weight? and if so at what rate?

Hello, all dieters have different weight loss results. Some users lose weight faster/slower than others.


Is there any thing in this product that would make your labs, drug panel come up dirty. If so how long does it take to get out of your system?

Hello, provide your physician the ingredients and he will be able to respond to your question.