Updated: 06/13/2017
By Summer Banks May 11, 2017

We hear a lot of buzz about AMPK activation, the new technology from LA-3. We wanted to learn more, so our attention turned toward the ingredients, side effects, and clinical research. Additionally, we read through hundreds of user experiences and testimonials. Then, we summarized the details to give you the info you need.

LA-3 Readers: Click here to find out why we're giving away samples of our product, Dietspotlight Burn.

What is LA-3?

First off, LA-3 is a longevity activator. The ingredients are gynostemma pentaphyllum leaf [1], quercetin dihydrate [2] and berberine HCl [3]. The supplement helps you fight fat in the abdominal region through a process called AMPK activation. AMPK is an enzyme that tells the body to stop storing fat, and in return converts it to energy. This leads to a reduction in cravings, slimmer waistline, and less fatigue.

Live Cell Research is the company behind LA-3. The company also offers a variety of wellness supplements, including Niagen, Midogen, Vitalstem and Cerastim. The official website sells the supplement and offers discounts on multiple-bottle purchases. We like the focus on total-body wellness and that the supplement contains natural ingredients, but read on…

Customer Service Quality – “An Essential Principle”

The first thing we tackled was the level of support from the LA3 customer service team. “Live Cell Research is a newer company,” said our Research Editor. “But, the level of support is light-years ahead of the rest.”

“They came right back to me on Facebook,” commented a customer.

“Came with the box opened and only one bottle of the three I ordered. I called them and they sent me three new bottles at no extra cost and they sent it right away,” stated a consumer.

LA3 Ingredients – “Effective”

Based on LA-3 reviews, customers see results. “I have never taken a product where I have felt an immediate result. This product is incredible,” said a dieter.

“It’s amazing, better then any diet I ever tried. First week of using LA-3 I felt the difference in my body now I’m on week three and I feel so good and no longer feeling sluggish, more energized,” stated a user.

“There has been a gradual increase in energy, mental clarity and focus, and reduced appetite,” reported a customer.

“It took a full 30-day supply for me to finally realize the benefits of advertised results. Still fighting the belly fat but didn’t expect it to go away in 30 days,” commented another.

Our years of research shows that when a supplement works, there’s a greater chance of long-term success. There’s a benefit to results customers notice from LA-3.

The Science – “Research-Based”

We picked apart the official website and found that there’s clinical research supporting the claims made by Live Cell Research, relating to LA-3. The company offers detailed information about the role of AMPK. [4] [5] We Also located studies showing the benefits of quercetin [6] and berberine [7]. At DietSpotlight, science is critical. With this particular supplement, we found evidence supporting it.

Also: read our Dietspotlight Burn Weight-Loss Kit review »

The Bottom Line – Does LA-3 Work?

Will LA3 be the key to activating your longevity? Well, based on review and research, there’s a chance that you’ll notice results. There’s solid science supporting the claims. As with any supplement, results vary. But, with this one, it’s apparent that users see positive changes. You want to lose weight and improve overall health.

Why not consider going with a supplement containing a formula supported by positive customer reviews.

Among the best supplements we’ve seen this year is the product Dietspotlight Burn. It contains four clinically-tested ingredients with supportive results published in peer-reviewed journals showing improved metabolism, decreased weight and increased fat loss. Users all over the web report amazing results.

The Dietspotlight Burn company stands behind the product, and they’re so confident that they’re offering a Special Trial Offer.

LA3 is all about getting that energy going and helping you live longer.

LA-3 Ingredients and Supplement Facts

Serving Size: 2 Capsules
Serving Per Container: 30
Amount per Serving% DV
Gynostemma Pentaphyllum Leaf Extract450mg*
Quercetin Dihydrate100mg*
Berberine HCL100mg*

Other Ingredients: None

  • References
  • 1. (). . .
  • 2. (). . .

LA-3 Questions & Answers:

We found hundreds of user comments about LA-3, often called Active-PK to create this helpful FAQ. What are the side effects of LA 3? LA 3 or LA-3 side effects, reported by customers, may include a mild headache. What are the ingredients in LA-3? LA-3 ingredients are gynostemma pentaphyllum leaf extract [1], quercetin dihydrate [2], and berberine hcl [3]. What is the active ingredient in LA-3? The active ingredient in LA-3 is Gynostemma pentaphyllum leaf extract. Does LA-3 work? There are studies showing that the ingredients in LA-3 may be effective in enhancing mental clarity and focus. There are reports showing it also helps reduce stress. How much does LA-3 cost? A one-month supply of LA-3 costs $46.99. How should I take LA 3? It is recommended that you take two capsules per day with a glass of water. Can I take LA3 if I have a health condition? Women who are pregnant or nursing, those with health conditions, anyone taking prescription medications or under the age of 18 should contact a licensed physician before using any dietary supplement. What do users like about LA 3? Some users said they enjoyed the increase in energy and improved health benefits while taking LA-3. What do users NOT like about LA-3? Some users didn’t like they didn’t find LA-3 sooner. How do I contact the LA-3 customer service department? You can contact the LA-3 customer service department by calling 844-650-5933, emailing support@livecellresearch.com or by mailing letters to Live Cell Research 10866 Washington Blvd. Suite #815 Culver City, CA 90232. Can I contact LA3 through social media? You can contact the makers of LA3, Live Cell Research, through Facebook and Twitter. Is there an official website for LA-3? Yes, there is an official website for LA–3. Does LA3 contain stimulants? There are no stimulants in LA3. Do you know of any special deals or discounts on LA-3? There are special deals and discounts on LA-3. If you buy a 90-day supply, you will get 56% off the price with free shipping. Also, if you buy the 180-day supply of LA-3, you will get 59% off the price with free shipping. Another one that we’re keeping an eye on is Dietspotlight Burn. The company offers a Special Trial Offer. Click above to learn more.

Learn More About Dietspotlight Burn »
Dietspotlight Author
About the Author:

Summer Banks, a content strategist at Dietspotlight, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 2.8. From 226 votes.
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Leave a comment or review

How long it to be used?

How long do I need to use this product, is that a lifetime thing or it has a time limit?

Montana (Editor)

Hello Elana! For detailed product and usage instructions, please refer to the LA-3 official website for more information.

Is it available in Europe?

Is LA-3 available in Europe?

Montana (Editor)

Hi Zlatko! For more detailed information, please refer to the LA-3 official website.


I have a problem with large amount of caffeine, I get heart palpitation, does this product have caffeine for energy booster?

Montana (Editor)

Hi Graciela! For more information on LA-3 ingredients, please refer to their official website.

What part of the body does it target?

Does this help with Visceral Fat?

Victoria (Editor)

Hi Greg! All users are different and can experience different results.

Can I use it with other products?

I am taking Truvision diet pills which curve my appetite. I want to start taking the LA 3. Does anyone know if I can take them together or not?

Victoria (Editor)

Hi! Because of possible interactions with taking these products together, please make sure to consult with your physician before combining them.

What are the instructions?
Deanie Browning Holland

I have a question, I have ordered this for my son. I would like to know when is the best time to take (Am vs Pm)? and if taking with or without food?

Victoria (Editor)

Hi! For detailed product and usage instructions, please refer to the LA-3 product label or official website for more information.

Can't find this product
Ebenezer kwarkye

I am Ebenezer in Ghana West Africa. How do I purchase LA 3?

Victoria (Editor)

Hi! For more information on where to purchase this product, please refer to the LA-3 official website.

Can it affect hormones?

Is this product good for women over 50’s that are going through menopause and hot flashes, not that has any relations but, I’m afraid to get more hormonal side effects, please help

Victoria (Editor)

Hi Mary! Please make sure to consult with your physician before starting a new weight-loss program or product.

I take medications..

Was wondering if LA3 works well with someone that has cholesterol, thyroids problems high blood pressure and diabetes 2 , also taking meds for the heart?

Victoria (Editor)

Hi Angela! Because of possible interactions with medications and certain health conditions, please make sure to consult with your physician before taking this product.

Side effects question
Diana Carballo

Has anyone experienced an increase in heart rate? faster?

Victoria (Editor)

Hello Diana. All users are different and can experience different side effects; please make sure to consult with your physician before taking this product just in case.

We'll see what happens
Tereasa Heilman (Verified User)

I’m on day 3. I have no intention of changing anything in my daily activities. It either work’s or it doesnt. Not everyone’s body is influenced positively upon taking the same product so i hope it helps me.

Not sure yet
Kim (Verified User)

I will start on day 8 tomorrow. Can’t say if it’s working or benefiting just yet. However, I plan to start an exercise to routine to loose my belly fat

My experience..

When I started taking LA-3 I did feel energy.


Grate fresh ginger root and steep it like tea. Strain and drink the liquid. Works miracles for Type 2 diabetes. Check your blood sugar before doing this because there days I don’t have to take meds. My A1C 9. I’m below 5 now and on my way down to normal



Tom K

How often are you drinking the ginger, 1 or 2 times daily, weekly ?


I haven’t really followed this thread but am curious if the ginger root tea is in addition to the LA-3?


The minute I started using LA-3 I noticed a drastic change in my energy level, that was 2 days ago when I received my 3 bottles. Personally I’m impressed, I got on the scale this morning and I had lost 5 lbs in just 2 days, unheard of for me as I am almost 66 years old and have no trouble gaining wait but loseing it is much harder. I’ve gotten more inspired to do the projects that have sat for months even years. Honestly I think how this stuff works is individual and it is working for me!!

Lisa D.

The instructions clearly say to take two capsules with a glass a water first thing upon rising in the morning. I’ve been consistent in doing this, and have had phenomenal success in gaining energy and losing inches (and my ‘love handles’), and I’ve only been taking it for three weeks.


Day 2 and my energy levels are up , had breakfast although not really hungry but am dieting also ,so we will see what happens


I was concerned about the weight loss because I am a petite person and not wanting to lose weight with the exception of the abdominal and waist budge. I am experiencing the loss in appetite. I have to make myself eat to not lose weight. The abdominal budge has not gone down as I would like. I have taken 1 bottle and I am on my 2 one. I am happy with the boost in my energy level. If I don’t see the budges dwindle by the time I finish the 2nd bottle, I won’t invest in this product again. There are some pluses and some negatives.


This has been the same results for me. I concur on the pros and cons.


I feel the same way! The 1st bottle I had more energy, lost 8lbs and was feeling good about this product.


Just started my first dose yesterday. I almost immediately noticed an increase in energy. I’ve been battling a cold and after taking LA-3 I was able to get up and function. I am excited to see what the results will be.


Just started this and will try for 3 months. I don’t remember anything being said about being a weight loss product. It claims to revitalize aging cells.

Jo Cook

As far as I understood it from the video on facebook they’re not promoting LA-3 for weight loss it’s more to help your organs be more healthy that are covered in deep fat and helps reduce said fat which in turn will have health benefits and an added benefit could be weight loss but ultimately your organs will be a lot healthier which would help reduce the possibility of all sorts of health related issues. You’re giving the impression it’s soley for weight loss which as far as I understand it from the video is totally not the case.


I watched the video on fb & it states they are not promoting this for weight loss, but as a deep fat reducer. Now, it might just me, but if you reduce the deep fat, which is supposed to be the cause of people getting fat, then if you reduce this deep fat, then you should lose weight… it’s just my thoughts.

Elias Samaha

I’m not actually over weight but I have a fatty liver

Juts my 2 cents worth

I’m not in this for the weight loss just the fat around my organs

Cathi Paradysz

LA-3 is a great product my first month I lost 6 lbs 3″ in waist 2″ in hips It’s now been 9 weeks on it I lost 18lbs
5″ in waist & 4 inches in my hips. I heading to be a diabetic AC1 was 6.8 now 6.2 Sugar was 148 now 112.
By my next blood test I will be back in order on my AC and sugar this is a life saver for me. Plus I haven’t even exercised that show how good this LA-3 is helping your blood levels and your organ. Those who said it
doesn’t work must not be taking it at the same time everyday. I had just order another 6 bottles I can’t say enough about this LA-3 product. Like the other people had said it’s not a diet pill it’s helping get rid of the fat cell that have built up on your fat cell. If it’s not working for you what did you lose nothing money back guaranteed most products don’t even guaranteed your shipping back.
For the people that it is working for stay with it you will have a healthier body in the long run.

Cathi Paradysz

  No apparent benefit.
Larry Sprague (Verified User)

I have been using this product for over 60 days along with dieting and exercise. I do not see any extra benefit with taking the LA-3. Any weght loss I have seen is consistent with the diet and exercise program I am on. I was looking to see a noticeable difference by using LA-3, but there was none.

I'm a smoker
Carlos Singletary

I smoke can i use la3

Victoria (Editor)

Hi Carlos. Because of possible interactions with smoking, please make sure to consult with your physician before taking this product.