Metabolic Nutrition Review - 11 Things You Need to Know

Metabolic Nutrition has been around for three decades, but does that mean the company produces better, more effective supplements? The only way to find out is to dig into the research behind the formulas. Our research team pulls back the curtain on Metabolic Nutrition with reviews of ingredients, side effects, customer testimonials and more. Check out the bottom line on this long-time supplement provider.

Metabolic Nutrition can be purchased through their Official Site.

What is Metabolic Nutrition?

Metabolic Nutrition is a 30-year-old company that was started by Dr. Murray Cohen. Their area of expertise is sports nutrition and wellness supplements plus health and nutritional supplements. The goal is better health through better nutrition. The company’s commitment to quality produces a product that’s supposed to be ideal for athletes yet suitable for an ordinary person who just wants to be in good health.

Before diving deeper into Metabolic Nutrition’s popular products, let’s look at what science says about some common ingredients used by the company. 

• Critical Reviews in Food Science and Nutrition – Based on a review of research that was published in 2018, “caffeine intake might promote weight, BMI and body fat reduction.”
• Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy – Though not much research can be found on the impact of taking digestive enzymes on weight loss, we were able to find studies that showed the inhibition or suppressing of certain enzymes promotes weight loss. According to this study, particularly enzymes that affect lipid and carbohydrate digestion.
• Phytotherapy Research – Bitter orange has been compared to ephedrine ever since that stimulant was banned in 2004. However, recent research shows the active ingredient, p-synephrine, doesn’t impact heart rate or blood pressure. A large review of research published in 2017 shared bitter orange has been shown to support “weight management, sports performance, energy, and appetite control.”

Metabolic Nutrition Competitors

Who Makes Metabolic Nutrition?

Metabolic Nutrition takes full credit for the manufacture of its products. They envision, research, develop, test and manufacture their product themselves. Dr. Cohen created Metabolic Nutrition to address nutrition deficiencies that lead to health problems.

Metabolic Nutrition Customer Service

Metabolic Nutrition prides itself on superior customer service. They appreciate and encourage customer feedback. They can be reached by phone at 1-800-626-1022 and are available from 9:00 am – 5:00 pm EST, Monday through Friday. They can be emailed at customerservice@metabolicnutrition.com. Emails are answered during business hours.

Popular Products From Metabolic Nutrition

Metabolic Nutrition’s top-selling products include Metabolic Nutrition Synedrex, Metabolic Nutrition Protizyme, Musclean and their patented Tri-Pep formula. 

• Syndrex is a pill meant to increase energy while dropping fat. 
• Protizyme is a protein powder. 
• Musclean is a muscle maintenance solution. 
• Tri-Pep prolongs amino acid delivery for the purpose of building strength, endurance and muscle size.

Scroll below for one of the best products we’ve seen over the last year.

Metabolic Nutrition Claims

Metabolic Nutrition promises high-quality nutrition and wellness supplements. The philosophy is that proper nutrition helps to achieve better health. The goal is to develop nutritional supplements in order to address the multiple metabolic issues many modern people must face. Health and wellness are a priority for Metabolic Nutrition, but they also make claims for improvement of athletic performance.

Metabolic Nutrition Ingredients

Let’s take a look at what goes into Metabolic Nutrition’s flagship products. We’ll look at Synedrex and Protizyme right now.

Synedrex

• Caffeine Anhydrous
• Eria Jarensis Extract
• Grains of Paradise
• Bitter Orange Extract
• Yohimbine HCL
• Higenamine
• Hordenine
• Huperzine A
• Naringin
• N-Phenylethylamine
• L-Dopa
• Poly-Thyronine

Protizyme

• Amylase
• Protease
• Cellulase
• Galactohydrolase Lactase
• Lipase
• Betaine
• Pepsin
• Papain

Do Metabolic Nutrition Products Work?

Caffeine anhydrous is powdered caffeine commonly used in supplements. One capsule of Synedrex contains 300 mg of caffeine. That’s very close to the upper limit suggested by health groups of 400 mg of caffeine intake daily. Not only has caffeine been shown over years of research that it’s helpful in weight loss, but recent research in the European Journal of Clinical Nutrition shares it also helps with weight maintenance after weight loss.  

Eria Jarensis Extract is a mood booster banned in Australia for causing problems with the human dopaminergic system. (Made people feel a little too good.) We were unable to find a single piece of research to support any claims Metabolic Nutrition makes about this ingredient.

Grains of Paradise is a spice comparable to ginger. According to the British Journal of Nutrition, grains of paradise supplements increase total body energy expenditure by activating brown adipose tissue.

Amylase is an enzyme that converts starch and glycogen into simple sugars, according to Regulatory Toxicology and Pharmacology. 

Protease is an enzyme that breaks down protein. It’s used in everything from waste disposal to therapeutics. “Proteases may also be consumed by humans and animals as digestive aids,” according to Industrial Biotechnology and Commodity Products.

Cellulase is an enzyme that breaks down cellulose. The human body cannot break down cellulose on it’s own. We were unable to find human research into the impact of supplementation on digestion, but an animal study published in the Journal of Agricultural and Food Chemistry states that cellulase increases fiber degradation in the gut.

Lactase is an enzyme that breaks down lactose or milk sugar. The majority of recent research has been on the impact of supplementation on premature infant growth and development, based on our research in the Cochrane Library.  

Metabolic Nutrition and Weight Loss

The ingredients in Synedrex, like caffeine, bitter orange and yohimbine, among others, have shown promise in helping weight loss. The high caffeine content may be off-putting for the average person trying to lose weight. Someone looking to use the supplement along with significant exercise may notice improvements in muscle growth, power, and recovery.

As for the Protizyme, this enzyme-enriched protein powder could be easier to digest and thus more readily available to muscles. Again, this appears to work better for people looking to improve exercise performance and recovery.

Metabolic Nutrition Side Effects

Metabolic Nutrition recommends discontinuing Syndrex if you experience rapid heartbeat, dizziness, severe headache or shortness of breath. The side effects of Protizyme are nearly non-existent. Standard warnings apply; not for someone pregnant or nursing, not for people under 18, do not exceed recommended dose. 

Cost and Where to Buy

You can buy Metabolic Nutrition products anywhere that sells vitamins and supplements. They are also available on Metabolic Nutrition’s online store. Synedrex currently goes for $49.99 for sixty capsules. Protizyme currently goes for $39.99. Both prices are from the official online store.

Pros and Cons

Most of the real pros and cons of the products can only be gleaned from people who have actually used them. Let’s look at the Metabolic Nutrition reviews.

Pros

• Products claiming to support weight loss actually contain some effective ingredients.
• Metabolic Nutrition is upfront about product ingredients.

Cons

• Metabolic Nutrition prices are on the higher end. 
• Excessive caffeine intake can cause serious side effects.
• Many supplements are based on proprietary blends making it hard to ascertain effectiveness.

What Users Are Saying

“One use of this product caused me severe GI distress that was far worse than any protein powder I’ve tried in the past. The flavor was very good, but the GI distress the product caused makes the product unbearable. Returning.”

“Taste is sweet, but not unbearably so. It gives me a ton of energy with minimal tingling and no anxiety.”

“Excellent light flavor. Mixes well with berries and eggs. No typical residue feel and taste as with most protein shakes.”

Bottom Line on Metabolic Nutrition Results

The supplements offered by Metabolic Nutrition contain at least some clinically tested ingredients. Results have varied over the years, but at least a few have shown promising results for weight loss, digestion, muscle growth and recovery, energy, and more. This company isn’t a bad business, if you will, but products like Synedrex may be too stimulating for the average person who’s not used to consuming lots of caffeine in one shot.

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