If you haven’t looked closely at garcinia cambogia now’s your chance. Our in-depth review looked at this the ingredient, possible side effects, and clinical research. We read countless comments and testimonials. Then, we condensed the facts to give you the information you need to answer the question – what does garcinia cambogia do?
What Is Garcinia Cambogia?
Most garcinia cambogia reviews place it under the label of tropical plants and fruits because it can be found as a wild plant species in the region of Southeast Asia, but it has also been reported to grow in parts of Polynesia, Australia and even Africa.
Garcinia cambogia has been under the magnifying glass of Western supplement markets and medicine due to its reported medical qualities. The plant is reported to have between 50 and 300 varieties, each with unique health properties distinguished by natives and locals.
The most widely commercialized variety on this side of the world is the one related to weight loss, as that variety is believed to have appetite suppressant properties.
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Garcinia Cambogia Fruit
The best known garcinia cambogia fruit highlighted in almost every garcinia cambogia review is the purple mangosteen, grown mostly in Southeast Asia, and with the highest international impact. It is a very odd-looking fruit, it vaguely resembles a hairless peach, but the inside looks like an interesting mix of garlic and cotton. This is the garcinia cambogia fruit from which most of the weight loss supplements are created.
Second in importance internationally is Kandis (AKA G. forbesii), which is a round, red, small fruit with a slightly acid taste, and melting flesh. Also worth mentioning are two additional versions of mangosteen present in many garcinia cambogia reviews: lemon drop mangosteen and button mangosteen. All of them can be used for their health benefits.
Garcinia Cambogia Extract
The best-known and most commercialized garcinia cambogia health benefit is the appetite suppressant quality. That particular extract comes from the exocarp of the purple mangosteen. Although its effectiveness has not yet been proven, and there are some severe contraindications, commercialization of garcinia cambogia has grown. 
Garcinia Cambogia Facts
According to Wikipedia, many species of the garcinia cambogia family are in danger of extinction due to habitat destruction. Wiki says the benefits and side effects of this fruit as a weight-loss supplement need more study, and cites hydroxycitric acid as a potentially negative and somewhat toxic ingredient. Wiki paints garcinia cambogia with a somewhat negative picture. 
How Did Garcinia Cambogia Use Start?
The use of this plant for medicinal purposes has been widely documented for more than two thousand years in Ayurvedic practices. In fact, garcinia cambogia is such an integral part of this ancient system that it can be found as part of one of the eight foundational components described in the early Sanskrit manuscripts. Its character of Rasayana puts it in a category believed to benefit each and every system within the human body.
Garcinia cambogia was traditionally used extensively to treat rheumatism. Despite its elevated presence in the Ayurvedic system, the plant really took off in terms of public exposure due to a study on rats in the 1970s. The study results were a reduction in the animals food intake by 25%. This brought garcinia cambogia to the attention of Western markets, and supplements based ongarcinia cambogia weight-loss benefits hit the market.  
Garcinia Cambogia Ingredients
Let’s take a look at the main ingredients in Garcinia Cambogia:
- The main ingredient: HCA (Hydroxycitric Acid) – This is the element in the rind of the fruit, and is what every Garcinia Cambogia review is talking about. HCA content is over one quarter of the fruit´s weight, and is what causes appetite suppression as well as providing the fat-burning boost.
- Flavonoids – These are phytonutrients that can be found in almost every fruit. Flavonoids are beneficial for the immune system, and have positive anti-inflammatory benefits as well as antioxidant properties. Flavonoids are associated with the benefits of a diet that is rich in fruits and vegetables, according to research being done by the Linus Pauling Institute. The preventive effects of cancer and neurodegenerative and cardiovascular diseases has yet to be proven, but are currently being tested.
- Xanthones – The pericarp of the mangosteen fruit contains this ingredient, which is another phytonutrient crucial in helping the body be rid of free radicals. Xanthones are antioxidant and prevent metabolic breakdown of all kinds. This ingredient is found in a part of the fruit that is very rarely consumed, therefore, the xanthone content was only recently noted. 
Does Garcinia Cambogia Work?
There has been a lot of money invested in trying to prove human results of the weight loss benefits found in mice, without much success. There is a very powerful scientific explanation about this that most reviews don’t share.
The citrate lyase in rats and mice plays a huge role in their fat-control system, while the part citrate lyase plays for humans is insignificant in the overall process. This seemingly tiny, but very significant variance results in very minimal positive results vs. placebo in humans, when double-blind tests were held.
Several sources, like Examine.com, state that this dietary supplement is manufactured and sold on such a large scale primarily because it is so cheap and abundant, and that its lack of proven effectiveness has not been widely discussed. The Journal of Obesity stated on December 14th, 2010 that the conclusion of their study of the Garcinia cambogia is that the fat-loss being generated by it is only partially effective in the short term and is of a very small degree.  
Garcinia Cambogia Premium
Garcinia Cambogia Premium is a brand that can be found almost in every store in the United States (except it is not one of the available brands for Garcinia Cambogia at Walmart, which is an interesting fact). The claims of the company behind it, also named Garcinia Cambogia Premium, state that there are no other chemicals or components in a capsule that is 100% vegetable.
According to the Better Business Bureau (BBB) the company is no longer in activity, nor were they ever accredited by BBB, therefore it can not be stated with certainty that it is a real company manufacturing in an FDA approved laboratory, despite their website claims. That being said, according to the package and many reviews, it can be a safe way to try out this weight-loss supplement out.  
Garcinia Cambogia Benefits And Results
Garcinia Cambogia and Diabetes
Garcinia cambogia results of preliminary tests carried out on with mice in June 2005 were very promising . Mice who were given a dose of garcinia cambogia 5 times higher than the recommended human dose, showed glucose absorption at a slower rate, and also had a slighter peak in blood sugar than those who did not receive any. Another article more recently published in the ‘Journal of Young Pharmacists’  that succeeded at reducing blood sugar in diabetic mice after feeding them with garcinia indica extract for four weeks.
Garcinia indica and cambogia are not exactly the same, so further tests are being carried on to test these results on garcinia cambogia, and to see if they can also be recreated in humans suffering from Type 2 Diabetes. Results were published in September 2010. The effects on the levels of insulin have had their own tests and in April 2003, the article “Fitoterapia” published a study done with mice who were given a high-sugar diet for four weeks and supplemented with garcinia cambogia, who showed lower insulin levels than those who did not receive the supplementation.
Garcinia Cambogia and Weight-Loss
According to clinical research, science is on the fence with how garcinia cambogia works in the body to promote metabolism function, or weight loss, if you will. For instance, in the Journal of Obesity, “The magnitude of the effect is small, and the clinical relevance is uncertain.” The report goes on to state, “Gastrointestinal adverse events were twice as common in the HCA group compared with placebo in one included study.” So, the participants saw a slight change in weight (maybe) but gastrointestinal effects were also an issue. 
The big issue we keep coming across when research the effects of garcinia cambogia on weight loss is that a large percentage of research is completed on animals, not humans. And, in some cases, the study authors don’t even bother to reveal which was used.
Take this comprehensive review shared in Fitoterapia, “Studies have shown that the extracts as well as (-)-hydroxycitric acid (HCA), a main organic acid component of the fruit rind, exhibited anti-obesity activity including reduced food intake and body fat gain by regulating the serotonin levels related to satiety, increased fat oxidation and decreased de novo lipogenesis.” Notice no participant information, other than in-vitro and in-vivo, are mentioned. Interestingly enough, there’s mention in this study about possible toxicity as well. 
Garcinia Cambogia Results
All tests regarding garcinia cambogia and its multiple potential benefits show only slight and short term negative or positive results.
Details On Garcinia Cambogia And Weight Loss
Every garcinia cambogia review aims to prove that the product based on this extract is a miracle pill for those suffering from obesity, or for those wanting to take a shortcut to a slimmer figure. Although heavy marketing and advertising campaigns are being made all the time, the results from the lab tests and studies cannot back up product claims.
According to the study published by the Journal of Obesity, the difference between placebo and garcinia cambogia was just two pounds. These results were not strong enough to state that the weight loss wasn’t due simply to the diet or exercise plan the participants were participating in. While there are few significant positive results found in humans, tests on mice continue, with very promising results.
Garcinia Cambogia and Weight Loss
The question “Does Garcinia Cambogia work?” is repeatedly asked online, and so far, the only answer available is that there is not enough medical evidence to say that it works for weight loss. It is important, in this case, to read beyond user comments and delve into clinical research before starting supplementation with garcinia cambogia. 
How To Use Garcinia Cambogia
Examine.com best describes how garcinia cambogia should be used, “Standard dosing of Garcinia Cambogia and its bioactive, (-)-Hydroxycitric acid, is 500mg of (-)-Hydroxycitric acid taken 30-60 minutes prior to a meal and usually taken at up to three different meals daily.”
However, even this research team admits that evidence of efficacy is lacking, “It is unsure if this is the ideal dose since human studies usually fail to find a benefit with any dosage.” 
Potential Garcinia Cambogia Side Effects
Extensive testing on humans has not been done for any of the v products on the market.Some users have reported the following symptoms after ingesting supplements:
- Dry Mouth
- Liver Issues
A warning was distributed by the Food and Drug Administration concerning all products that contained any form of garcinia cambogia, because in 2009, some random users reported severe liver problems. Although the product that caused these liver problems was not 100% pure garcinia cambogia, all users should be aware of potential garcinia cambogia side effects on the liver.
Garcinia cambogia side effects have been widely covered. The “Consumer Reports” website advises users of any kind of dietary supplements to include a healthy diet and some exercise, and also warns about garcinia cambogia side effects.
Garcinia Cambogia Product Warnings
Garcinia cambogia might have negative interactions with the following medications:
- Diabetes medicines such as insulin
- Cholesterol-lowering drugs
- People with psychiatric conditions who are taking prescribed medication
- Iron prescribed for anemia
- Any kind of asthma medicine
- Painkillers of all kinds
Pregnant or nursing women should refrain from taking this supplement, along with people with any sort of kidney or liver problem. 
Any Garcinia Cambogia Lawsuits?
The FTC (Federal Trade Commission) reports an open case under the title “Slash Sale Refunds” due to fraudulent use of email address to ‘spam-advertise’ weight loss supplements with fake IDs. Garcinia cambogia is one of the supplements included. 
Garcinia Cambogia and Dr. Oz
Garcinia cambogia was named “the miracle pill” by TV celebrity Dr Oz. This controversial claim resulted in a hearing at the Senate level, requesting Dr. Oz to back up his claims with medical data. Since he was not able to do so, he was advised not to use such “flowery language” when referring to supplements. The doctor’s website has since taken a different stance on how consumers should use supplements for weight loss. 
Garcinia Cambogia Alternatives
A sugar extracted from the hard exoskeletons of crustaceans including shrimp, lobster, and crabs.
- How does it work – It supposedly blocks cholesterol and fats before they are absorbed by the human body. 
- Is it effective –The National Center for Complementary and Integrative Health found no evidence in weight-loss treatments with Chitosan.
Green Coffee Extract
The extract comes from unroasted coffee beans.
- How does it work – Claims to reduce appetite so you eat less and lose more. 
- Is it effective – There have been tests performed but there is no conclusive evidence to state it is effective in weight-loss treatments.
Found naturally in your body, and can also be taken as a pill.
- How does it work – Boosts the metabolism, allowing a higher amount of calories to be burned throughout the day. 
- Is it effective – Small studies were done and those who took 7-Keto-DHEA lost more weight with diet and exercise than those who didn’t. More clinical tests have to be done to determine effectiveness.
What Users Are Saying
“Since using this product I find my hunger has decreased and I am losing inches and weight. Very happy with results and we’ll continue using product.”
“This product worked very well for what it promised. It’s a great appetite suppressant and I did not experience any side effects. What I discovered, which is common sense dieting, is that it doesn’t suppress cravings. So while I may not be hungry for the chocolate, I sure did still crave it.”
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“Helped curb appetite. It was okay, didn’t continue using once it was gone. No drastic results.”
The Bottom Line – Does Garcinia Cambogia Really Work?
So, is garcinia cambogia for weight loss the real deal? We appreciate that it is a natural fruit extract, but we’re concerned about this one it’s not backed by solid science backing the claims.  The reality is there are few published clinical trials to support this ingredient. And even when studies, HCA included, are supportive, they are often completed on mice. 
For those interested in cutting excess body fat and slimming down fast, we suggest going with a weight-loss supplement backed by clinical studies, not fad ingredients.
Among the best products we’ve seen this year is one product called Burn HD. It combines four clinically-tested ingredients with results often found in publications such as The American Journal of Clinical Nutrition. What do users tell us about it? They say they see great results.
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