Updated: 01/09/2018

Methyldrene Elite Review - 5 Things You Need to Know


The results of my research into Methyldrene Elite were somewhat surprising. Here we are with an in-depth review of the product. We covered the ingredients, side effects, clinical study and customer service quality. We also scoured the web for user experiences. With that in mind, we condensed and refined to give you the info you need.

Methyldrene Elite Readers: Click here to find out why we're giving away samples of our product, Burn HD.

What You Need to Know

Firstly, Methyldrene Elite is a fat-burning supplement that uses caffeine, white willow bark, ephedra, ginseng and citrus aurantium. When taken in pill form, Methyldrene Elite claims to provide an intense burst of energy, appetite suppression and fat-burning. You can find it for about $30 from a couple of obscure online retailers, but it is small enough to take on the go.

We couldn’t find any determinate information online about the company, Cloma Pharma, behind Methyldrene Elite and there is no mention of when this supplement was released. The moderate cost and the guaranteed results are certainly positives, but read on…

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Side Effects – “Health Concerns?”

The first thing we felt important to note about Methyldrene Elite ingredients was the potential for side effects. “Yes, taking ephedra has been clinically proven to boost energy and metabolism,” says our Research Editor. “Unfortunately, the FDA took it out of the diet market in 2004 because of reported health problems. It is these potential Methyldrene Elite side effects that worry us.”

The National Institute of Health has ephedra listed with “significant safety concerns reported.” Nausea, heart palpitations, anxiety and mood changes are just a few possibilities.

When taken along with caffeine, the chances of side effects are multiplied. One question we do have is whether or not the supplement contains ephedrine, the leading alkaloid and cause for concern in ephedra. We can’t tell from the product descriptions, but dieters may want to steer clear.

Legal – “A Serious Concern”

As we mentioned before, ephedra was banned from the diet industry more than 10 years ago. We have no way of knowing if Cloma Pharma uses the real thing in the supplement or just an imitation, but if it’s the real deal they could be held legally responsible for its sale and use.

When we visited Cloma Pharma’s website, everything was shut down except for a recall notice by the FDA for three of their products, including Methyldrene Original. Apparently the company experienced a salicylic acid  contamination in some of their supplements, not a good sign. No other information could be found.

We have found that supplements have to avoid bad side effects and other issues to provide long term success for users. Methyldrene Elite provides nothing but red flags everywhere. The risk of adverse reactions is enough for us to give this one a thumb down.

The Science – “Is It Proven?”

Believe it or not, there is plenty of research into Methyldrene Elite. Caffeine, ephedra and white willow bark combine to make the classic ECA stack. Clinical studies have shown increased metabolism and weight-loss with this formula. But, the dieter must take into account that the FDA banned the main ingredient in 2004 because of serious health issues. At DietSpotlight, we like to see published support, but that’s not enough to counteract the risk in this case.

The Bottom Line – Does Methyldrene Elite Work?

So, the time has come to tell you the final verdict on this one. We are usually suspicious of products that can’t be found on reputable websites and that don’t have many user reviews. All we really know about Methyldrene Elite is that it uses an ECA stack that has caused severe side effects in the past and is now illegal in the diet industry. The company behind it, Cloma Pharma, is in the midst of an FDA recall. Things don’t look good, so we are hesitant to recommend this supplement to dieters.

We suggest the use of a product that is both legal and safe. Losing a few pounds is not worth a significant health risk and you need to find a company with many reviews and scientifically proven ingredients.

Among the best products we’ve seen this year is one called Dietspotlight Burn. It uses a blend of four ingredients that have all been clinically proven to help burn fat and boost metabolism and the online reviews look great. We haven’t even found mention of side effects.

Oh, and the makers of Dietspotlight Burn are offering a Special Trial Offer for the time being, which always shows confidence in the product.

Learn More About Burn HD »
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Methyldrene Elite

What are the side effects of Methyldrene Elite?

Methyldrene Elite side effects may include nausea, heart palpitations, anxiety, and mood changes.

What are the ingredients of Methyldrene Elite?

Methyldrene Elite ingredients include vitamin B6, vitamin B12, chromium, caffeine anhydrous, panax ginseng extract, white willow extract, citrus aurantium extract, cayenne pepper extract, ephedra nevadensis PWD, MCT oil PWD, phenylethylamine HCl, bocapa monniera, black pepper extract, yohimbine extract, methylsynephrine, and bauhinia purpurea L.

How do I know if Methyldrene Elite is right for me?

Choosing the right product is the #1 question asked by DietSpotlight readers. We recommend trying any product before buying it and know that finding a product with a sample offer is near impossible - so we created our own product, Burn HD, with scientifically backed ingredients.

Click here to get your sample of our powerful fat burner today.

Does Methyldrene Elite work?

There is lots of clinical research that helps prove a combination of caffeine, ephedra, and white willow bark helps kindle weight-loss. However, the FDA banned ephedra in 2004 because of serious health issues. The company that makes Methyldrene Elite has also had to recall three of their products because of concerns from the FDA.

If you are looking for a product that is both safe and customer reviewed, you should check out Dietspotlight Burn.

How much does Methyldrene Elite cost?

Methyldrene Elite’s cost starts at $32.95 for a 100 capsule bottle.

What is Methyldrene Elite’s BBB rating?

Methyldrene Elite is not BBB accredited.

How should I take Methyldrene Elite?

Methyldrene Elite should be taken twice a day. One capsule should be taken with breakfast and one with lunch.

Do I need to diet in order to use Methyldrene Elite?

You do not need to diet in order to use Methyldrene Elite, although you may want to think about the benefits it may have for your weight-loss journey.

Does Methyldrene Elite target a specific area of weight?

No weight-loss supplement has been proven to target a specific area of fat, including Methyldrene Elite.

Does Methyldrene Elite come with a guarantee?

Methyldrene Elite does not come with a guarantee.


Previous Methyldrene Elite Review (Updated January 24, 2014):

What You Should Know

Methydrene Elite is an ephedra supplement. The ingredients we found in the supplement are a classic ECA (ephedra, caffeine, aspirin) stack. This stack is no longer legal for use in diet supplements, according to the Food and Drug Administration. If this supplement contains real ephedra, and not some other extract of the same plant, the manufacturer, seller and buyer could be held legally responsible for the sale and purchase.

List of Ingredients


  • Vitamin B6
  • Vitamin B12
  • Chromium Picolinate
  • Caffeine Anhydrous
  • Ephedra Extract
  • White Willow Bark
  • 1, 3 Dimethylamylamine
  • Methylsynephrine
  • Phenylethylamine
  • Citrus Aurantium
  • Yohimbine HCL
  • Bauhinia Purpurea
  • Panax Ginseng
  • Bocapa Monniera
  • Cayenne
  • MCT Oil PWD
  • Black Pepper Extract

Product Features

Before taking out your credit card to purchase Methyldrene Elite, you may want to have your doctor do a full physical paying special attention to heart health. Methyldrene Elite contains caffeine, ephedra, citrus aurantium, methylsynephrine and yohimbine. These are all stimulants, with ephedra being one of the strongest stimulants on the planet. Ephedra is also addictive, as is caffeine. As if that long list of stimulants weren't enough, Methyldrene Elite contains 1, 3 Dimethylamylamine. This stimulant is associated with heart palpitations and other negative side effects. If you have a heart condition, liver disease, kidney disease or any other major health condition, you should not take this supplement because it could cause serious side effects.

Moving out of the stimulant category, we find phenylethylamine. This ingredient is included to boost the mood of the dieter. If the dieter feels happier, they are more likely to stick with the program and lose more weight. However, this small positive benefit is outweighed by the fact that some users have reported side effects similar to those associated with street drugs. Hallucinations and an extreme feeling of euphoria are two of the more common side effects.


  • Ingredients for Methyldrene Elite are listed online.
  • The supplement will increase metabolism and weight loss.
  • The dieter will likely feel less hungry.


  • Methydrene Elite contains ephedra.
  • This supplement is illegal for sale in the United States.
  • The ingredient list shows a dangerous combination of stimulants.
  • The mood-altering ingredient may cause negative side effects similar to street drugs.


We rarely come across ingredient lists like the one listed for Methyldrene Elite anymore. When the FDA banned ephedra for use in diet supplements, the market calmed down a bit, but there are still a few companies hanging on to those old formulas known to cause horrible side effects for some dieters.

Before taking this supplement, contact the manufacturer and inquire about the source of ephedra and how this supplement is still being sold in the United States without FDA regulation.

Summer Banks Dietspotlight Author
About the Author:

Summer Banks, Director of Content at Dietspotlight, has researched over 5000 weight-loss programs, pills, shakes and diet plans. Previously, she managed 15 supplement brands, worked with doctors specializing in weight loss and completed coursework in nutrition at Stanford University. full bio.

4 Methyldrene Elite Reviews

  • Harish

    I am 31 years can. I take take this capsules

  • Need to know the side effects
    manoj saini (Verified User)

    What is tha side effects methyl drene

    • Maribel (Editor)

      Hello Manoj. All users are different and can experience different side effects; please make sure to consult with your physician before taking this product.

  • Joe

    It really works buying all I can before they take it off the market how ever it makes me shake a little and feel a bit nauseous but wow lay 25 lbs quick and with out trying I’m down to 175 lbs haven’t weighed this since high school!