Updated: 04/18/2017 - Site operated by Leptigen
By Summer Banks Mar 26, 2017

This review is what happened after I obsessed for weeks over Advantra Z. We put the spotlight on side effects, ingredients, and clinical studies. We took in hundreds of dieter comments and reviews. Then, we summarized and condensed the info to give you the facts you need.

Advantra Z Readers: Click here to find out why we're giving away samples of our product, Leptigen.

What is Advantra Z?

First off, Advantra Z is a stimulant derived from the bitter orange plant. There are hundreds of supplement lines that sell this brand-name synephrine or citrus aurantium. The ingredients vary by brand but may include p-synephrine, n-methyltyramine, hordenine, octopamine and tyramine. It promotes weight-loss by increasing the breakdown of fat cells and boosting thermogenesis. You can find it listed as an ingredient in over-the-counter dietary supplements. [1]

Advantra Z was touted as the “next generation ingredient” when it was introduced in 1996 by Nutritech. It’s sold through supplement stores and at local retailers. We like that it’s easy to locate and that we found some positive customer comments, but read on…

Adverse Effects – “Safety First”

The first concern we had was with Advantra Z side effects. “The ingredients in this one act similar to several stimulants on the market,” said our Research Editor. “Some people have complained of nausea, headache, heart palpitations, jitteriness and high blood pressure after taking it.” [2]

According to WebMD, “When taken with stimulants such as caffeine or caffeine-containing herbs, increases the risk for high blood pressure, fainting, and other severe side effects.” [3]

One customer commented, “This stuff is not safe! Makes my heart pound like crazy!”

We found some users that didn’t notice negative side effects while using Advantra Z. [4]

“No headaches, anxiety or irritability,” commented a dieter.

Advantra Z User Complaints – “Not a Positive”

The comments posted about Advantra Z weren’t always positive. One person said, “Way too many side effects from this stuff. No thanks. It’s not worth it.”

“My doctor told me this product is not safe, so I can’t really use it for weight-loss,” said another.

On the other hand, some users shared their positive experiences using it. “It gives me the boost I need in the morning. I remember not to drink any coffee though,” reported a customer. [5]

“It’s cheap and effective. That’s all I care about,” stated another.

Our extensive research has revealed that if there is a certain aspect of a weight-loss pill that’s concerning, like negative customer comments, long-term success could be reduced. If customers aren’t happy after using Advantra Z, there’s a problem.

The Science – “Solid?”

For us at DietSpotlight, we need to see some clinical research that actually supports the product we’re investigating. Fortunately, we did locate some clinical studies that support the effects of Advantra Z in regards to weight-loss. This ingredient does appear to boost thermogenesis, especially when combined with stimulants such as caffeine. However, on the downside, adding the two stimulants together can increase the risk of side effects. [6]

The Bottom Line – Does Advantra Z Work?

So, should you run out and buy Advantra Z? Well, we like that there are some clinical studies connecting the herb to weight-loss, but we’re concerned about this one because the same research shows it causes harmful side effects. We’re also a bit skeptical about it because of the negative customer comments and reviews posted online.

If you’d like to drop more weight, then we suggest going with a supplement not connected to harmful side effects, contains clinically proven ingredients promoting weight-loss and is backed by positive user reviews.

Among the best products we’ve seen this year is one called Leptigen. This product promotes weight-loss by offering a blend of four key ingredients, which have been shown to help accelerate fat loss and elevate metabolism. We can’t find any comments about harmful side effects and user feedback reveals people are seeing excellent results.

The makers of Leptigen are so confident about their product, they’re offering a Special Trial Offer, which is a positive sign.

Previous Advantra Z Review (Updated January 1, 1970):

What You Should Know About Advantra Z

Advantra Z is a patented ingredient that is present in a number of weight loss supplements. The company that manufactures Advantra Z is Nutretech. One of the major active ingredients in Advantra Z is bitter orange extract, which is also known as Citrus Aurantium. Advantra Z can be found in weight loss products such as Miracle Burn and Nuphedrine. The manufacturers of Advantra Z say that it is the only patented thermogenic ingredient for sale today.


The ingredients in Advantra Z are: Bitter Orange Extract, Protein, Carbohydrate, Omega 3 and 6, Sodium, and Vitamin A and C.

Product Features of Advantra Z

Advantra Z is not for sale as a stand alone supplement, so if you want to use it as part of your weight loss program you will have to buy one of the weight loss products for sale which contain this ingredient. Two such products are Miracle Burn and Ephedrine. Both of these products contain Advantra Z, as well as Hoodia Gordonni. Hoodi Gordonni is derived from a cactus that is said to have appetite suppressing qualities and can be found in the South African and Namibian deserts. There is an import ban on products containing Hoodia in Australia, so if you live in Australia you will not be able to order Hoodia-based weight loss supplements like Miracle Burn or Nuphedrine.

The manufacturers of Advantra Z say that it is a safe alternative to the now-banned Ephedrine, which was previously present in a number of thermogenic weight loss products. However, a number of dieticians have mixed feelings about Bitter Orange Extract, which is one of the major ingredients in Advantra Z. They say that the chemical components in Bitter Orange Extract, namely Synephrine and Octapamine, can lead to problems with high blood pressure and heart complications. It would seem advisable, therefore, that anyone with pre existing blood pressure or heart problems should not take Advantra Z.

There are testimonials available online for both Miracle Burn and Nuphedrine, which are both products that feature Advantra Z as a key active ingredient. Some say these products have helped them lose weight, while others say that they have had to stop taking it due to side effects such as headaches, dizziness and shakiness. Of course, it is unclear whether Advantra Z was the ingredient responsible for the negative health complications that resulted from taking these weight loss supplements.

Advantages of Advantra Z

  • Products containing Advantra Z are available for sale on line
  • There are testimonials available written by those who have already tried various products containing Advantra Z.
  • There is an ingredient list available for Advantra Z.

Disadvantages of Advantra Z

  • There have been some reported side effects related to products containing Advantra Z.
  • Advantra Z cannot be purchased as a stand alone supplement.
  • Those with heart or blood pressure problems should not take products containing Advantra Z.
  • There have been no controlled standardized tests carried out that we could find focusing on products containing Advantra Z.


At the end of the day there do seem to be some safety concerns regarding Advantra Z, and therefore we would prefer not to recommend products such as Miracle Burn or Nuphedrine which contain this component. Once we have seen the results of controlled standardized tests relating to the safety and to effectiveness of Advantra Z as an ingredient, we'll begin to consider it. Often, when a new "miracle" ingredient makes its debut in weight loss supplement formulas, we like to wait several years to see if what kind of long-term effects (positive and negative) this ingredient has.

Advantra Z Questions & Answers:

We narrowed down hundreds of customer reviews about Advantra Z and made this helpful FAQ.

What are the side effects of Advantra Z?

Advantra Z side effects reported by some customers include jitteriness, nausea, upset stomach, irritability, sleeplessness, anxiety and nervousness.

What is in Advantra Z?

The ingredients in Advantra Z are p-synephrine, n-methyltyramine, hordenine, octopamine and tyramine.

What’s the active ingredient in Advantra Z?

The active ingredient in Advantra Z is p-synephrine.

Does Advantra Z work?

There are several studies showing Advantra Z could potentially cause thermogenesis and possibly help with weight loss. But the finding did include additional stimulants in the research.

Take into account what you want out of a supplement like Advantra Z and then consider a product like Leptigen, which contains some clinically-tested ingredients.

How much does Advantra Z cost?

The cost of Advantra Z isn’t listed on the official website. You will need to contact the customer service department for pricing. Supplements that contain Advantra Z vary in price.

How should I take Advantra Z?

You should take 100mg to 120mg of Advantra Z up to three times per day. The company adjusts the servings, based upon your end goal and if a supplement contains additional ingredients such as caffeine or other stimulants.

Can I take Advantra Z if I have a health condition?

Women who are pregnant or nursing, those with health conditions, anyone under 18 years of age or people taking prescription medications should contact a healthcare provider prior to using any weight-loss supplement, including Advantra Z.

What do users like about Advantra Z?

We found some dieters liked the low cost of Advantra Z supplements.

What do users NOT like about Advantra Z?

Some users didn’t like the Advantra Z side effects.

How do I contact the Advantra Z customer service department?

You can contact the Advantra Z customer service department by calling a representative at 1-973-882-7773, emailing info@nutratechinc.com, by mailing correspondence to Nutratech 10 Henderson Dr. West Caldwell, NJ 07006 or by sending messages through the feedback form.

How is Advantra Z sold?

When you purchase Advantra Z from the parent company, you can buy the powdered, granulated, water-soluble or the debitterized form.

Are there different potencies of Advantra Z?

Yes, Advantra Z comes in 5%, 6%, 10% and 30% potencies.

If a supplement contains bitter orange, is it the same as Advantra Z?

No. Advantra Z contains only p-synephrine, while supplements containing bitter orange may include m-synephrine and additional synthetic ingredients.

Does Advantra Z come with a guarantee?

Advantra Z doesn’t come with a guarantee. You can contact the customer service department for information relating to returning the product.

Do you know of any special deals or discounts on Advantra Z?

There are no deals or discounts listed on the official Advantra Z website. However, our readers have been going wild over the past several months taking advantage of Leptigen’s Special Trial Offer, which is just the cost of shipping and handling. Click here to give it a try.

  • References
  • 1. (). . .

Advantra Z Ingredients and Supplement Facts

Serving Size: Varies
Serving Per Container: Varies
Amount per Serving % DV
Citrus Aurantium * *

Other Ingredients: None

  • References
  • 1. (). . .
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Dietspotlight Author
About the Author:

Summer Banks, a content strategist at Leptigen, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 3.8. From 4 votes.
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Hello I’m Lucy I just started using phenq sat 15,2016 the bottle is suppose to be the one on ad