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BioXgenic Size Review - 9 Things You Need to Know

Bioxgenic-size is a male enhancement supplement. The company claims the supplement helps to support blood flow for firmness, improve performance in the bedroom, and maximize stamina. Some research contradicts whether or not some ingredients used in the product help with sexual desire.

Along with the fact that some research done on the ingredients of the product contradict one another, many of the ingredients are focused on solving erectile dysfunction which is not the purpose of the product. Our research team investigated deep into the science and individual ingredients of the product to see if this supplement is worth it. Here is a summary of what our research team found.

BioXgenic Size can be purchased through their Official Site.

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What is BioXgenic Size?

BioXgenic Size is a supplement that is manufactured by M.D. Science Lab, LLC. It’s made especially for men and, according to the official website, should not be taken by anyone under the age of 18 or people who have had hormone-related cancers.

The purpose of the supplement is to improve blood flow to the penis, thus making erections firmer and leading to better stamina and sexual performance.

BioXgenic Size is made from a proprietary blend of ingredients, which makes up 1,650 mg of the 2,000-mg serving, as well as a few other substances.

BioXgenic Size ingredients in the proprietary blend are:

  • Yohimbe (dried aqueous extract, bark)
  • Astragalus, Maca, Panax Ginseng, Sarsaparilla (root)
  • L-Arginine (as Arginine HCL)
  • Avena Sativa (leaves)
  • Catuaba, Muira Puama (bark)

Even more ingredients from the proprietary blend include: Taurine, Nettles (leaf), Orchic Powder, Oyster Shell, Tribulus Terrestris (fruit), Cnidium Monnieri, Pumpkin (seed), Xanthoparmelia Scabrosa (aerial parts), and Boron (from Boron Citrate Aspartate)

Bioxgenic Size

Other ingredients include:

  • Vitamin B3 (niacin) – 25 mg and Zinc (from amino acid chelate) – 50 mg
  • Solutab ™ and Dicalcium Phosphate
  • Cellulose
  • Magnesium Stearate
  • Silica

Products Similar to BioXgenic Size

Prime Male
Ageless Male Max

Who is M.D. Science Lab, LLC?

According to the BioXgenic website, M.D. Science Lab, LLC has been manufacturing “lifestyle products” since 1999.

Their LinkedIn account shows that they are located in Fort Lauderdale, Fl.

BioXgenic says their products are “FDA compliant and CGMP regulated.”

CGMP stands for “Current Good Manufacturing Practices.” That means they are required to follow a standard for ensuring quality products that are safe and effective.


BioXgenic Size Ingredients – What is in BioXgenic Size?

bioxgenic ingredients

First, let’s take a look at a couple of the claims that BioXgenic makes on their website concerning two of their ingredients: Cnidium monnieri and xanthoparmelia scabrosa. They say these two components are “widely acknowledged as precursors for PDE-5 inhibition.” But, does science agree? Let’s find out.

PDE-5 inhibitors, or phosphodiesterase type 5 inhibitors, are a kind of drug used to treat erectile dysfunction (ED). They work by blocking PDE-5, a substance that harms the smooth muscle cells in the blood vessels that supply the blood needed for an erection.

Cnidium Monnieri

Cnidium monnieri is a plant that grows in China. Its fruits, seeds, and other parts are used to make medications.

Traditionally, Chinese medicine has used cnidium to treat skin conditions. Some people do take it orally to manage ED and improve sexual performance and drive.

However, they also say that there is insufficient evidence to support the effectiveness of cnidium for use to treat sexual dysfunction.

In a review in Translational Andrology and Urology of traditional Chinese medicine used to treat ED, scientists stated that cnidium fruit contains a substance called osthole. This material is a vasodilator. In a test conducted on rabbits, osthole relaxed the corpus cavernosum, the erectile tissue.

However, the review goes on to say that most of the studies they reviewed for Chinese herbs involved animals, not humans, so there is more research needed.

It should also be noted that the study looked at using the fruit of cnidium, not the seeds.

Xanthoparmelia Scabrosa

Xanthoparmelia scabrosa is a lichen, which is comprised of fungus and algae.

We were unable to find any scholarly articles that linked xanthoparmelia scabrosa to the effective treatment of ED.

We also want to note that ingredients are usually listed in order of the amount of the substance in the product, with those having the most significant amount first.

Cnidium monnieri and xanthoparmelia scabrosa are both listed toward the bottom of the label, indicating they are probably present in relatively low amounts.

So, even if they were effective, there’s no way of knowing how much of each substance is used or whether it’s enough to have any effect.

Considering these are the two substances that the website touts as being “unique” to BioXgenic Size, we’re pretty sure that it’s not much different from all the other products out there.


Yohimbe comes from an evergreen tree that grows in Africa.

According to the National Center for Complementary and Integrative Health, a division of the U.S. Department of Health and Human Services, “there is very little research in people on the effects of Yohimbe as a dietary supplement. But studies have documented the risks of taking it.”

We’ll get into the side effects of Yohimbe later, but that’s not a very encouraging statement.

They go on to say, “Yohimbe sold as a dietary supplement may not work like the prescription medication that contains yohimbine.”

Maca Root

The information we found concerning maca root is conflicting. A review of studies published in the journal titled Evidence-Based Complementary and Alternative Medicine found some studies that showed promise, but others that found maca to be ineffective.

One group of researchers said, “In a randomized study we were unable to demonstrate the effect of maca on penile erection in apparently healthy adult men.”

But, another group found a “significant positive effect of maca on sexual dysfunction or sexual desire.” Considering that researchers don’t agree, we can’t say either whether maca root is effective or not.


The news on L-arginine is a little more encouraging. An amino acid, L-arginine helps the body to form protein.

L-arginine is a vasodilator and that research evidence suggests that it may be useful for treating men with ED as a result of a physical cause.

Avena Sativa

Avena Sativa is the scientific name for oats. Although oats are useful for reducing heart disease risk and lowering cholesterol when eaten, there is no research related to male sexual function.

Panax Ginseng

Panax ginseng is also called red ginseng. A review published in the British Pharmacological Society journal suggests that while there have been studies that show promise in the use of red ginseng for treating ED, “the total sample size and the methodological quality of the primary studies were too low to draw definitive conclusions.” So, once again, there isn’t enough proof that this ingredient works.


Vitamin B3 (Niacin)

Well, Vitamin B3, also known as niacin, is undoubtedly beneficial for health.

It can raise good cholesterol levels, slightly lower bad cholesterol, and reduce triglycerides.

It may also be useful for improving heart health.

But, does it have any effect on male sexual performance? There is some scientific evidence that suggests niacin may be helpful for erectile dysfunction.

A study in the Journal of Sexual Medicine concluded that “niacin alone can improve the erectile function in patients suffering from moderate to severe ED and dyslipidemia.”

So, okay, niacin might be beneficial, but couldn’t a man take a Vitamin B3 supplement, which is likely less expensive, instead?


Next up, zinc. Again, zinc is essential for good health and has specific health benefits, such as supporting a healthy immune system, according to the American Journal of Clinical Nutrition.

People have used it to try to treat erectile dysfunction, but there’s insufficient evidence that it works, says the Central African Journal of Medicine.

That doesn’t stop it from being used in supplements like Nugenix from adding it.

One study in the Journal of Sexual Medicine conducted on rats showed that taking too much zinc can reduce libido.

Rats who received 1 mg of zinc daily showed no difference from the control group.

Rats who received 10 mg daily showed a decrease in libido.

BioXgenic Size side effects

Side Effects

BioXgenic Potential Side Effects

The BioXgenic Size ingredients list is long so that we won’t go through the side effects for every ingredient, but we’ll hit the highlights for you. According to WebMD:


  • Abdominal pain and bloating
  • Gout
  • Diarrhea
  • Allergies and worsening of asthma symptoms
  • Low blood pressure and abnormalities in the blood
  • Inflammation of airways

Panax ginseng

  • Insomnia
  • Rapid heartbeat, irregularities in blood pressure, and headaches
  • Diarrhea
  • Itching and rashes
  • Dizziness


  • Flushing
  • Headaches and dizziness
  • Upset stomach and gas
  • Mouth pain


  • Vomiting
  • Nausea
  • Diarrhea
  • Metallic taste
  • Damage to the kidneys and stomach

And as noted, the National Center for Complementary and Integrative Health had some worries about Yohimbe. They say that it has been linked to:

  • Heart attacks
  • Seizures
  • Stomach problems
  • Tachycardia and High blood pressure
  • Anxiety

According to Dr. Anthony Dugarte, “Anything with vasodilatory properties may cause an unsafe drop in blood pressure.”


BioXgenic Benefits

The official website for BioXgenic Size says that it provides “impressively improved sexual performance, stamina, and firmness.” This is a boon for anyone with sexual problems looking to boost their sex life, sexual health, or assist with male enlargement. They also list:

  • Rapid response
  • Blood flow support for firmness
  • Performance improvement
  • Stamina enhancement

BioXgenic also says that one of the benefits of their product is that they use “safe, natural ingredients.”

bioxgenic cost


How Much Does BioXgenic Cost?

BioXgenic Size can be purchased from the company’s official website or at Walmart, CVS, Amazon, or VitaminShoppe. BioXgenic sells a 30-day supply of 60 capsules for $49.99 plus shipping.

Pros & Cons

BioXgenic Size Pros and Cons


  • No stimulants
  • May enhance sexual health
  • Few side effects
  • Natural ingredients


  • Not a lot of evidence
  • Can’t be proven safe
  • Effectiveness unverified

What Users Are Saying

“Work just like described but drink plenty of water. Need to cycle through them. Take daily 2 months then cycle off for 1 month and take with Bio Hard.

“Did nothing for me.”

“Works great.”

Bottom Line

The Bottom Line on BioXgenic Size

Alright, so here’s what we think in a nutshell. There are some beneficial ingredients in BioXgenic, like niacin and zinc, which is a good thing. We also like that the ingredients are natural. The company does claim that it currently adheres to FDA regulations and CGMP regulations. But, we’re not entirely sold on the product.

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What are the ingredients in BioXgenic Size?

Maca, Nettles, Pumpkin Seed, Taurine, Zinc, Di-Calcium Phosphate , L-Arginine, Oyster Shell, Sarsaparilla Root, Orchic Powder, Silica, Vitamin B3, Muira Puama, Magnesium Stearate, Avena Sativa, Boron, Astragalus Root, Yohimbe Bark, Catuaba Bark, Cnidium Monnieri Seed, Panax ginseng Root, Tribulus Terrestris Fruit, Cellulose, Xanthoparmelia Scabrosa,

What are the side effects of BioXgenic Size?

User’s of BioXgenic Size can experience upset stomach, dizziness, nausea and rapid heart beat.

Does BioXgenic Size work?

3.2 stars out of 5 stars on GNC, users state they can feel a difference using this product.

What is the price of BioXgenic Size?

$34.99 at GNC.com.

How should I take BioXgenic Size?

BioXgenic Size should be taken twice a day, one tablet in the morning and one tablet in the evening.

Where can I buy BioXgenic Size?

BioXgenic Size can be purchased using their Official Site.

How do I contact BioXgenic Size customer service?

You can contact customer service at 1-888-657-1717 x 1308 or on their website.

Can I return BioXgenic Size?

Depending on where you buy BioXgenic Size returns may or may not be allowed.

What are the most common complaints about BioXgenic Size?

Users who used BioXgenic size did state that they had discomfort in their genitals.

5 BioXgenic Size Reviews

  • Felix

    Does it enlarged the size of the penis

  • Tony

    For how long should one use the product

    • Montana (Editor)

      Hello Tony. According to the product’s directions, BioXgenic Size should be consumed every day for the best results, though they do not specify for how long.

  • biogenic size
    Rakiease (Verified Purchase)

    how long does it take for it to work

    • Victoria (Editor)

      Hi Rakiease, according to the company, results may vary.