Updated: 04/18/2017 - Site operated by Leptigen

Nuphedrine Review - Does This Fat Burner Really Work?

  • 90 User Comments
  • Rating: 3.4. From 172 votes.
By Summer Banks Mar 09, 2017

I’m obsessed with finding the right diet products that actually work. Let’s find out if Nuphedrine is one of them. After looking at the ingredients, side effects, clinical research, and customer service, we had a pretty good idea of what was going on. But, we also looked to hundreds of reviews to learn more. Then, we condensed it all to give you the facts you need.

Nuphedrine Readers: Click here to find out why we're giving away samples of our product, Leptigen.

What is Nuphedrine?

Firstly, Nuphedrine ingredients are Advantra-Z, hoodia, and Slimaluma. These are well-known non-prescription ingredients that are supposed to help suppress the appetite and boost metabolism. Based on packaging, you can take it along with you anywhere.

We don’t know the company behind Nuphedrine, but we do know it has been available since 2009, according to the official website where it is sold directly. We like the before and after pictures, and the 60-day money back guarantee, but read on…

Side Effects – “No Fun!”

Our first concern is the Nuphedrine side effects some users reported. “Supplements with stimulants are known for causing side effects for some users. Two of the main ingredients are stimulants, so it’s no surprise, really,” said our Research Editor.

”I felt jittery after I used this,” said a dieter.

Another shared, “I experienced insomnia the whole time I took this pill.”

Fortunately, not everyone experienced side effects while using the supplement.

“I didn’t experience any side effects while using this supplement,” said a reviewer.

“I expected to, but did not feel any side effects,” claimed another.

Nuphedrine Fad Ingredients – “May Not Be What You Think”

Nuphedrine advertises using genuine South African hoodia. The reality is the real thing is hard to find, and is expensive. We cannot confirm whether or not the ingredient is real, or a knockoff.

”I don’t think the hoodia is real, because I didn’t see any difference with this supplement,” said a user.

”I don’t think the hoodia is real, because it’s just so expensive to get the actual stuff,” was another thought.

Regardless, some people feel it is legitimate because of their results.

“This stuff really works!,” said a reviewer.

“I lost 10 pounds in a month with this stuff,” according to a dieter.

Over the years, we’ve found it takes a small thing, such as side effects, to cause dieters to avoid a product. If NuPhedrine does cause negative issues, that could be enough to scare away the dieter.

The Science – “It Could Work”

The main ingredients in Nuphedrine are Advantra-Z and hoodia. The first is a stimulant that can boost heartrate and metabolism, though it has been associated with some irritating side effects. The second is not backed with strong clinical research and, based on our studies here at DietSpotlight, that likely means the results will not by what the dieter is looking for.

The Bottom Line – Does Nuphedrine Work?

Should you go out right now to get a bottle of Nuphedrine? We are on the fence. We appreciate the addition of a stimulant, but we’re worried about potential side effects. The hoodia is not effective at all, but the Slimaluma may have a little support.

If the time has come to jumpstart your metabolism, you may want to find a weight-loss product with clinically tested ingredients that’s not associated with harmful side effects.

Among the best products we’ve seen this year is one called Leptigen. Not only is it formulated with clinically tested ingredients known for their ability to support your weight-loss efforts, but our team wasn’t able to find any negative mentions of the product or harmful side effects. This lets us know people are getting solid results.

And right now, the manufacturer is running a Special Trial Offer so customers can give it a try.

Previous Nuphedrine Review (Updated June 3, 2015):

What You Should Know

At dietspotlight.com, we’ve looked at a lot of diet supplements, and Nuphedrine is one of the most cutting edge, non-prescription weight loss pills that we’ve seen. The main active ingredients, Hoodia and Advantra-Z, both may contribute to thermogenesis, which is when your metabolism is in optimal fat-burning condition. From our findings, Nuphedrine is one of the only products available which combines Real South African Hoodia in a 20X strength, Patented Advantra-Z® and Slimaluma. These are among the most well known non-prescription weight loss ingredients on the market. The makers of Nuphedrine have collected real before and after photos from happy customers documenting real-life weight loss success using this product. Recent compliance crackdowns have forced dozens of online diet pill manufacturers to take down false photos and testimonials, making the Nuphedrine site even more compelling.

Product Features

The official website also documents that the Hoodia used in Nuphedrine is the only form of Hoodia in America to be used in a clinical study documenting guaranteed weight loss. This was without adding exercise to their daily routine! Nuphedrine contains only certified authentic South African Hoodia, which is hard to find in America these days. In fact, each box comes with a certificate of origin from the South African government. Most companies use a synthesized domestic form of Hoodia that does not have the same potency as that from Africa. Another thing we love to see in a supplement: the makers of Nuphedrine are so confident that customers will like the product and every order is backed by a 60-Day Money Back Guarantee.


NuPhedrine® is the only product we have found that combines these three powerful ingredients and in the most optimal potencies: Real South African Hoodia in a 20X strength, Advantra-Z® in a 30X strength, and Slimaluma. 20X Strength South African Hoodia:
  1. Helps suppress appetite. Contains a compound called ‘P57’, which is a molecule that is designed to makes you feel full. The P57 molecule is much more potent than glucose in sending the signal to the brain that tells your body it is NOT hungry.
  2. More potent than dried, American-sourced Hoodia. Includes a certificate of authenticity from the South African government.
  3. 20:1 ratio rating. This rating refers to the drying ratio when the Hoodia plant is dried and milled. For every 20 lbs. of whole plant, you get 1 lb. of dried, milled plant material suitable for encapsulation.
  1. Boosts the metabolism. Advantra-Z® is the only patented non-prescription weight loss herb in America. It is patented for:
    • To help enhance weight loss
    • Aids in increasing lean muscle mass
    • Helps improve athletic performance
    • Designed to suppress appetite
  2. Only one supplier in America is licensed to produce this ingredients, so the market is not currently saturated with products that feature it.
  3. NuPhedrine contains the ‘Extra-Strength’ 30% version of the herb which is the only potency levels we found designed for optimum intake.
  1. Helps suppress appetite. The active compound in this powerful ingredient is designed to send a signal to the hypothalamus telling the brain that your stomach is full.
  2. Rather than suppressing your appetite all day long like Hoodia does, Slimaluma helps you not overeat when you do have a meal. It essentially makes a little food go much further.
NuPhedrine® definitely sets the bar. Out of all of the supplements we’ve seen, we feel that these are definitely the highest quality ingredients currently available.


  • Contains Advantra-Z® in the 30X potency
  • Contains guaranteed authentic South African Hoodia and each box comes with a Certificate of Authenticity from the S.A. Government.
  • Their Hoodia is a potent 20X concentration.
  • The formula also contains Slimaluma, which we feel is the perfect addition to Hoodia in overall appetite suppression.
  • They let the customers say it all – check out the before & after pictures.
  • Comes with a 60-Day Money Back Satisfaction Guarantee.


  • It is currently only available on the official NuPhedrine® Website and not sold in stores.
  • The formula will only be available for as long as the makers can source Real South African Hoodia. Customers may want to order large quantities now while they still can and take advantage of the NuPhedrine® 60-Day Return Policy if they are not satisfied.


In our experience, most products use the same cheap ingredients filled with caffeine and fake Hoodia (Advantra-Z® is the ONLY stimulant in NuPhedrine. It contains no caffeine or taurine.) That was the first thing about NuPhedrine that really got our attention; it is the only product available that combines REAL South African Hoodia in a 20X concentration with Advantra-Z®. As we took a closer look at this product, we realized it satisfies our other evaluation criteria as well. We were seriously impressed by the user testimonials and Before & After photos posted on the official NuPhedrine site. When we saw that it comes with both a Free Trial Period and AND a 60-Day Money Back Guarantee, we were stunned. In a market full of below-average products, we recommend NuPhedrine as one of the only solid choices out there.
Get Your Sample Today »
Dietspotlight Author
About the Author:

Summer Banks, a content strategist at Leptigen, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 3.4. From 172 votes.
Please wait...
Nuphedrine Review

How Does Nuphedrine Compare?

User Comments (90)


Sort by:   newest | oldest | most voted

I take a lot of prescription s and wonderif this is safe. Cholesterol meds, pain meds, sleeping pill at night, lyrica and symbalta

Lisa landsman

What is Nuphedrine


I went to the website to purchase NuPhedrine and I could not. Please tell me how to purchase some. Thank you

J Neilson

I read your review on Nuphedrine and decided to try it — however no matter how many times I input my name and address info into the blanks on the Nuphedrine site, it just reverts back to blanks, with no forward movement whatsoever — oh well.

Orpha Verneret

If someone is breastfeeding is it possible to take it?


CAN i take your product even if i already have medications???
Thank you

weston johnson

I am on hypertension & cholesterol meds and doing great but need to slim down some. would this affect my current meds.


Hi, You need to consult a physician. Please do not ask these types of critical questions in an open forum.


Hi,we looking for ensure with nephropathy includ for special diet please

sheri fister

Trying to order. Website will not work, keeps going back to the order page after I already put in the info. Help beacsuse I want to try it.


People…ephedra was banned for health reasons. What makes you think this product is any different. Its name Nuphedrine has the same suffix as ephedra. These products are stimulants that have deadly side effects. When i was working in the ICU I saw people go into cardiac arrest on these drugs. They speed things up…like your heart, causing potential lethal cardiac arythmias. Please DO NOT USE THESE DRUGS! they are unhealthy and deadly. Making changing your health patterns a challenge for 2014. Eat better, walk or ride a stationary bike, stay away from sugary carbs and replace with good fruits. respect your bodies for all they do and do polute them with drugs. change your habits instead.


Agreed! Completely!


I never trust things with a money back gaurantee


I was just wanting to know where I can find nuphedrine? Is it sold in stores?


I notice this has no caffeine…I have not had caffeine for over 25 years. I used to have heart palpatations so stopped with caffeine. Does this make you feel like you have had a stimulant that could cause same effects as caffeine? Thanks for response.


To take in combination with any other weight loss pills

annie Baumback

Do you ship to Canada?

Edwin Richel

Hey guys I see alot of you want to get toned but just want to take it for a short amount of time with no negative side affects take lol amounts such as 5 grams everyother day as creatine stays in your system for a long and rotate you work outs atleast 4 times a week you need to be dedicated lower body then upper body even if you only care about upper body gains take for about 3 months and a two week break in that time your body will start to do it’s own production of creatine then come back with the same cycle and when you stop most people don’t step down slowly as you should do for less losses as you body adapts and produces it’s own ceatine most people gain there strength back after two weeks even when they stop cold because that’s when it all is out of there system and they get back to producing there own but always stay hydrated for full gains and keep a lean diet will off creatine just like you were on it because that’s half peoples problems stop taking care of there body needs because there not on creatine if you go buy that you can have close to no loses that will not be hard at all to gain back AND YOU ALWAYS have those muscle cell you don’t loSE STRENGTH BECaUSE OF STOPPING


I would like to know if I can take Nuphedrin in conjunction with Avesil and/or Inflama-trim. Does anyone know if there would be any issues in doing this?


I’ve never been this overweight in my life. I weigh more now than I did when I was 9 mo. pregnant. I have to do something serious. I just purchased Nuphedrine, hope it comes soon. And as an extra boost, I also purchased the Flex Belt. I read as many reviews as I could on both. I was wondering if anyone else bought both and if so what was the result?


Angela, I was curious about the amount of water you drink daily. It is very important in weight loss programs – you did not mention WHAT you weigh now, and how much you want to lose. I can comment more if you reply – thanks! – Jim in NJ


sounds much like phen phen years ago but hopefully healthier. phen phen fooled your brain into thinking you werent hungry…only problem is once they banned it, everyone got fat again, you really need to change your life style, how you eat and exercise on a regular basis, there is no easy way out for once you stop the pills, its fat city again..


Sounds like it works the same ]way Phen Phen did years ago but (maybe) healthier outcome. I took Phen Phen, loved it. it blocked the part of the brain out which said I was hungry, I used to actually forget to eat so would carry saltines with me so I would eat something. lost so much weight, people in ny town who hardly knew me would comment on how good I looked. too bad phen phen was banned due to ONE wooman having a heart attack and dying….and the funny part is, she had existing heart issues before taking phen phen. her husband sued the company and won and everyone who had it and loved it,lost it and got fat again.