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Peptiva Review - 17 Things You Need to Know

Peptiva is a probiotic that is supposed to help you achieve a full night’s sleep and improve your digestion. Because the brand’s website claims that using the product will “restore your health,” we decided to see if the claim has any validity. From our research and knowledge about the industry as a whole, we have determined that this claim cannot be proven.

The primary problem with the claim that the company makes is that it promises Peptiva will lead to digestive health simply because the supplement helps you achieve better sleep. Our research team knows that other factors influence health other than sleep, and we are looking at all of the ingredients in Peptiva. Here are the results of our research into Peptiva’s effectiveness.

Peptiva can be purchased through their Official Site.

Peptiva Readers: Noom is offering our readers a free trial, for a limited time. Click here for this special offer!

What is Peptiva?

Peptiva Sleep Support claims it is a clinically validated probiotic supplement that is doctor-formulated. This over-the-counter digestive aid contains a multi-strain probiotic matrix and natural herbs to help restore digestive balance as you sleep.

It has guaranteed potency, and no refrigeration is required.

Peptiva is intended to help restore beneficial bacteria levels, which may in turn help restore your digestive health.

How Did Peptiva Start?

Peptiva was first released in 2017 as a dietary supplement intended to help alleviate digestive discomfort. Dr. David Katz helped formulate this probiotic supplement.

The Peptiva brand is owned by Adaptive Health. The company owns a long list of other popular brands, like Nugenix and Instaflex. 

Peptiva Customer Service and Contact Info

In regards to Peptiva customer service, they do offer a 30-day 100% satisfaction guarantee on the official website.

There is also a convenient contact form provided on the main site that allows you to submit questions and concerns at any time. A 1-800 number is also posted.

As for Peptiva contact information, it is listed on the website as follows:

2323 South 3600 West
West Valley City, UT 84119

Email: support@peptivaprobiotics.com

Phone: 1-800-355-6050


Peptiva Claims

The Peptiva probiotic supplement claims it can:

  • Renew digestive health
  • Alleviate digestive discomfort
  • Promote more restful sleep
  • Support healthy gut bacteria

This probiotic is specifically used at night because this is when the digestive tract is the least active. This is supposed to make it easier for the probiotics to take effect and replenish healthy gut bacteria.

Peptiva is said to be manufactured using a “proprietary Tri-Phase Dehydration process.” This is to guarantee the product’s potency through the expiration date on the package.


Peptiva Products

Peptiva offers a couple of different probiotic supplements, including Peptiva Advanced Digestive Relief, Peptiva + Sleep Support, and Peptiva Vegetarian Digestive Enzymes + Prodigest. 

Peptiva Advanced Digestive Relief is a daily probiotic that apparently boost your overall health. They ensure potency stays the same over time. The supplement also contains a “stress relief and calming matrix.” 

Peptiva + Sleep Support is a probiotic meant to be consumed at night. Apparently, this formula helps you gain digestive balance while you sleep. Valerian root and melatonin are also included to help you fall asleep faster. 

Peptiva Vegetarian Digestive Enzymes + Prodigest says it is an “advanced formula” that can help you get relief from boating and unpleasant gas. The formula contains 17 digestive enzymes and some herbs for maximum results. 

Peptiva Ingredients

Although Peptiva offers three different kinds of supplements, many of the bacteria strains and ingredients are the same. 

To gain a better understanding of how this product works to replenish healthy gut bacteria, we need to examine the ingredients in Peptiva, which include the following:

Lactobacillus Acidophilus

Also called L. acidophilus, this is a form of good bacteria and is the most commonly used probiotic. It assists by breaking down food in the intestine and restoring a healthy bacteria balance.

Bifidobacterium Bifidum

This is one of the most common probiotics found in humans and mammals. According to Frontiers in Endocrinology, Bifidobacterium bifidum helps by stimulating good/beneficial bacteria in the gut.

Bifidobacterium Animalis

Bifidobacterium animalis is found in the large intestines of humans and other mammals. It is also commonly found in fermented dairy products such as milk and yogurt. This bacteria may help relieve symptoms of constipation and other gastrointestinal issues.

Lactobacillus Rhamnosus

Lactobacillus rhamnosus is a probiotic strain often used in yogurt and dairy products, as well as supplements. It is a subspecies of L. casei, and helps prevent the growth of bad bacteria and may help restore your gut.

Lactobacillus Paracasei

According to “The Microbiota in Gastrointestinal Pathophysiology“, this probiotic strain is often used to balance and restore normal gut flora. Lactobacillus paracasei is found in kefir and yogurt.

Gamma-Aminobutyric Acid

Some people take Gamma-Aminobutyric acid (GABA) to elevate mood and enhance sleep, according to Frontiers in Psychology

Valerian Root Extract

According to Acta Medica Portuguesa, valerian root may help you fall asleep faster and even improve sleep quality.


Melatonin is a hormone that is found naturally in the human body. It can also be made synthetically in a laboratory. It helps the body regulate its sleep and wake cycles.

The body produces more melatonin when it is dark, which in turn gets the body ready for sleep.


According to the official website, “PRODIGEST® is a patented combination of 2 standardized ingredients: a lipophilic CO2 extract of ginger roots (Zingiber officinale Rosc.) and a unique extract of artichoke leaves (Cynara cardunculus L.) that has shown benefits for improved digestion, providing natural digestive relief.”

Benefits & Results

Does Peptiva Work?

Peptiva does contain six scientifically validated probiotic strains and a few herbal extracts that are supported by some clinical research.

Research published in the journal PLoS One concluded, melatonin has been shown to help with sleeping issues and may help you get to sleep more quickly, increase total sleep time and enhance overall sleep quality.

According to the American Journal of Medicine, valerian root demonstrated positive effects on sleep quality and helping people get to sleep faster.

Gamma-Aminobutyric Acid or GABA has shown some positive effects on both sleep quality and overall relaxation, says the Journal of Nutritional Science and Vitaminology.

Peptiva Benefits and Results

The Peptiva claimed benefits are simple – better digestive health, better sleep, and more healthy gut bacteria. This product contains no known allergens and is even considered vegan, so it does not contain any animal ingredients.

According to the website, you should feel calmer, more relaxed, less stressed and enjoy deeper sleep after only 30 minutes of taking Peptiva.

In 8-12 weeks, you should notice reduced abdominal discomfort, less bloating, better regularity, and improved intestinal health and function, according to the manufacturers.


Details on Peptiva and Weight Loss

Will this sleep support and digestive health supplement help you lose some weight? Let’s take a closer look.

A study in the Porto Biomedical Journal concluded the “probiotic effect in body weight is specific and strain-specific.”

According to the journal Nutrition & Metabolism, probiotics may help with the prevention and treatment of obesity.

Based on research presented in the journal Frontiers in Endocrinology, GABA might affect metabolic function, appetite and activity levels, according to LiveStrong.

According to the Journal of Pineal Research, “melatonin limits obesity in rodents without affecting food intake and activity, suggesting a thermogenic effect.”

Side Effects

How to Take Peptiva

To use Peptiva, you need to take one capsule 30-60 minutes before bedtime. It can be taken with or without food.

Furthermore, this supplement can be taken on a daily basis to achieve the maximum benefits. There is no special diet plan mentioned with Peptiva pills.

Also, each package of Peptiva has a shelf life of 18 months. This probiotics supplement should be stored in a cool, dry place, but does not require refrigeration.

Potential Peptiva Side Effects

While there’s no mention of side effects from Peptiva; there’s a chance some may notice side effects from Peptiva ingredients, including:

  • Headache
  • Upset stomach
  • Gas
  • Bloating
Product Warnings

What About Peptiva Probiotic Reviews?

You can find several Peptiva reviews posted on the official website. There are also user comments and remarks for Peptiva posted on dealer websites such as Amazon and GNC.

This product received 4 out of 5 stars on Amazon and 4 out of 5 stars on GNC. Naturally, these ratings may change over time. We encourage you to read some of the customer feedback because it will give you better insight as to what others have experienced while taking Peptiva capsules.

Results certainly vary from person to person.

Where to Buy

Peptiva Product Warnings

Always pay close attention to warnings that apply to any new products you consider. Here is a closer look at the Peptiva product warnings, according to the label:

  • Peptiva is for adult use only.
  • Peptiva may cause sleepiness and drowsiness.
  • Do not take Peptiva with alcohol.
  • Do not take Peptiva while driving or operating any heavy machinery.
  • If you are pregnant or nursing a child, consult a healthcare practitioner before using Peptiva.
  • If you have a serious medical condition, be sure to speak with a doctor before using Peptiva.
  • If you are already taking a medication, you must consult your doctor before taking Peptiva.
  • Certain prescription drugs and medications may interact with probiotics.
  • This product is not intended for use on animals.

Where Can You Buy Peptiva?

You can purchase this clinically validated probiotics and sleep support formula directly from the main website.

You can also buy Peptiva pills from dealers such as Amazon and GNC, as well as a few other online distributors including Gifts County, Bon Shoppe, and eBay.

Peptiva Cost

Since there are a couple different products from Peptiva, prices will vary. 

Peptiva + Sleep Support costs $59.99 per package. It is available on GNC for the same price. If you have a one time purchase on Amazon, the supplement costs $49.97, and a subscription costs $47.47. 

On the official website, Peptiva Advanced Digestive Relief costs $64.99. On Amazon, the supplement costs $49.99. 

Peptiva Vegetarian Digestive Enzymes + Prodigest costs $34.99 on the official website and GNC. You can also buy it for $29.99 on Amazon. 

Unfortunately, we did not find any Peptiva coupon offers online. However, the official website does mention that you can save up to 40%.

Peptiva Alternatives

You can find some alternatives to Peptiva online and in health supplement stores or drugstores. If you are specifically interested in supplements that contain probiotics and sleep aids, focus on products that use similar ingredients to Peptiva capsules.

Also, keep in mind that different products contain different ingredient portions. Therefore it is helpful to examine the supplement’s label to find out how much of each ingredient is used and how potent the formula is.

For those only interested in digestive support, there is Peptiva Advanced Digestive Relief. This is a little different from the Peptiva Plus Sleep Support formula.

It is still taken 30-60 minutes before bedtime but is not claimed to help with more restful sleep. However, it is claimed to do the following:

  • Replenish healthy gut bacteria
  • Alleviate bloating and discomfort
  • Help with irregularity
  • Promote relaxation and emotional well being

Again, you only need to take one pill each night, and it is also doctor-formulated. Peptiva Advanced Digestive Relief contains 50 billion active cultures, and the ingredients include:

  • Lactobacillus acidophilus
  • Bifidobacterium bifidum
  • Bifidobacterium animalis subsp. Lactis
  • Gamma-Aminobutyric Acid 100mg
  • Lemon Balm Extract 75mg
  • L-Theanine 200mg

This multi-strain probiotic blend also offers guaranteed potency and is said to restore digestive balance. It is available through online stores such as GNC and Amazon for $64.99 (30 capsules).

Bottom Line

What Users Are Saying

“Best probiotic ever! – I have been using probiotics for years due to my many stomach issues. This is by far the best one I have ever taken. After 2 weeks, I can tell a major difference within my stomach. I will definitely keep taking these and would highly recommend it!”

“Doesn’t work! – Bought sample and had very high hopes, but I didn’t sleep any better than my usual wakeful nights! Very disappointed!”

“Best in it’s class – These are the best in their class of probiotics and digestive support. I am not in a position to pay much for the support products. I do, however, feel the good I get out weighs a money issue. It is priced very well for the results achieved daily.”

The Bottom Line – Does Peptiva Work?

With clinically-backed ingredients to back up the claims made by Peptiva, we can’t deny that the product could be beneficial to your digestive health. It may even play a role in helping you sleep. However, when it comes to weight loss, it doesn’t seem like this product would be the one for you.

When you want to lose weight it’s the lifestyle changes you make that help you maintain that weight loss over the long-haul. However, it’s difficult to stick with these lifestyle changes without a little help and support. This is where technology comes into play.

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Dietspotlight readers can take advantage of a free trial of Noom to see just what it feels like to have the support you need to lose weight and keep it off.

Learn More About Noom »
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What are the ingredients in Peptiva?

The ingredients in Peptiva include:

  • Lactobacillus acidophilus
  • Bifidobacterium bifidum
  • Bifidobacterium animalis subsp. lactis
  • Lactobacillus rhamnosus
  • Lactobacillus paracasei
  • Gamma-aminobutyric acid
  • Valerian root extract
  • Melatonin
What are the side effects of Peptiva?

The potential side effects of Peptiva include dizziness, headache, bloating, irritability, gas and stomach cramps.

Is Peptiva a good probiotic?

Peptiva claims to be clinically-validated, but there’s no proof it’s clinically-proven. It is claimed to be beneficial to take at night since your body naturally resets at night.

What is Peptiva good for?

Peptiva is a probiotic used to support digestive function. The ingredients claim to help you better balance your health while getting better sleep.

What is the sleep aid in Peptiva?

The sleep aids in Peptiva are melatonin and valerian root. Healthier gut bacteria may also help aid in sleep.

Where can I buy Peptiva?

Peptiva can be purchased using their Official Site.

How long does it take Peptiva to work?

It takes about 30 minutes for Peptiva to work. The company suggests using the product for 8-12 weeks to see results.

How do I contact Peptiva customer service?

Peptiva customer service is reachable via support@peptivaprobiotics.com.

Can I return Peptiva?

Yes, you can return Peptiva within 30 days of receipt.

What are the most common complaints about Peptiva?

The potential side effects of Peptiva, which are a major cause of discomfort are the most common complaints about this product.

14 Peptiva Reviews

  • Beverly (Verified Purchase)

    I only wanted to try a sample. All of a sudden I am being shipped 30 capsules a month at a charge of $70.50. And, the product doesn’t even work for any of the symptoms advertised. Total rid off! When I called to cancel, the person on the phone was rude. Advice: do not buy this product!

  • The worst
    Karink (Verified Purchase)

    Horrible. Diarrhea for days.

  • not for me

    I had the bloating and irritability, unable to get a good night’s sleep. Stopped after 10 days.

  • Very weak
    Susan Parker (Verified Purchase)

    I was very dizzy the next morning and my legs were very weak after trying my first pill. Did no one else have the same complaint?

  • To much pain
    Evelyn Anthony (Verified Purchase)

    The headache and cramping are not worth the product purposes, bad reaction.

  • LAME.
    KATHY GARCIA (Verified Purchase)

    I was so happy to try it and so disappointed it didn’t work any better than everything else I’ve tried.
    I have struggled most of my adult life with the kind of problems this product was suppose to help but it did nothing. I would never pay for it.

  • Disappointed!
    Susan Nickel

    I have tried Peptivs many times over the years and it has done nothing to improve my sleep! I always am hopeful the ingredients kick in for me, but they don’t.

  • Ingredients not talked about!
    Amelia Dodson (Verified Purchase)

    Nobody has addressed the fact that there is red #40 and blue #1 in this product and yes they ARE potential allergens not to mention bad for you!

    • Loni

      EXACTLY – artificial color ingredients in a product that is suppose to benefit your health & gut???? No Thank You!!!! Plenty of broader spectrum pure probiotic products (sleep products too!)

  • I think there IS a weight control benefit
    Robert Chambers (Verified Purchase)

    I’ve been using Peptiva for about six months. Previously, I used Floramor. I’ve been quite impressed with Peptiva on the sleep assist and digestive regularity fronts. I decided to Google it to see if there were any weight control claims associated with it as I was unaware of any, previously. I’m an older athlete and I typically gain weight over the winter. That hasn’t happened this year and I believe the reason is the Peptiva and how thoroughly cleansed I feel all the time now.

  • Ann Crane

    Is peptiva safe to take with high blood pressure?

    • Angelica Almaraz

      Hello Ann,

      We recommend consulting with your physician before using any supplements that may conflict with any medical issues.

  • Greed in America2

    With all of these side effects you WILL CERTAINLY are going to sleep better!

    Stomach cramps

  • It works! Try it for yourself
    Patrick Paules (Verified Purchase)

    Peptiva works great without any side effects or waking up groggy. I am on a fixed income and can not afford the price of this product. However, you get the option to buy an extra box for $5.99. It is worth it.

    I have tinnitus and it is difficult falling asleep. I also have problems staying asleep because of a debilitating injuries I sustained to my spine. Without going into my problems this product works. Try the sample and you will also finally find the rest that has been missing from your life.