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Peptiva Review - 17 Things You Need to Know

Peptiva is a probiotic supposed to help you achieve a full night’s sleep and improve your digestion. Because the brand’s website claims that using the product will “restore your health,” we decided to see if the claim has any validity. From our research and knowledge about the industry as a whole, we have determined that this claim cannot be proven.

The primary problem with the company’s claim is that it promises Peptiva will lead to digestive health simply because the supplement helps you achieve better sleep. Our research team knows that other factors influence health other than sleep, and we are looking at all of the ingredients in Peptiva. Here are the results of our research into Peptiva’s effectiveness.

Peptiva can be purchased through their Official Site.

Peptiva Readers: Noom is offering our readers a risk-free trial, for a limited time. Click here for more information!

What is Peptiva?

Peptiva Sleep Support claims it is a clinically validated probiotic supplement that is doctor-formulated. This over-the-counter digestive aid contains a multi-strain probiotic matrix and natural herbs to restore digestive balance as you sleep.

It has guaranteed potency, and no refrigeration is required.

Peptiva is intended to help restore beneficial bacteria levels, which may in turn help restore your digestive health, but what does the research have to say about the components in this supplement?

Company Bio

How Did Peptiva Start?

Peptiva was first released in 2017 as a dietary supplement intended to help alleviate digestive discomfort. Dr. David Katz helped formulate this probiotic supplement.

Adaptive Health owns the Peptiva brand. The company owns a long list of other popular brands, like Nugenix and Instaflex. 

Peptiva Customer Service and Contact Info

Regarding Peptiva customer service, they do offer a 30-day 100% satisfaction guarantee on the official website.

There is also a convenient contact form provided on the main site that allows you to submit questions and concerns at any time. A 1-800 number is also posted.

As for Peptiva contact information, it is listed on the website as follows:

2323 South 3600 West
West Valley City, UT 84119

Email: support@peptivaprobiotics.com

Phone: 1-800-355-6050


Peptiva Claims

The Peptiva probiotic supplement claims it can:

  • Renew digestive health
  • Alleviate digestive discomfort
  • Promote more restful sleep
  • Support healthy gut bacteria

This probiotic is specifically used at night because this is when the digestive tract is the least active. This is supposed to make it easier for probiotics to take effect and replenish healthy gut bacteria.

Peptiva is said to be manufactured using a “proprietary Tri-Phase Dehydration process.” This is to guarantee the product’s potency through the expiration date on the package.

Product Line

Peptiva Products

Peptiva offers a couple of different probiotic supplements, including Peptiva Advanced Digestive Relief, Peptiva + Sleep Support, and Peptiva Vegetarian Digestive Enzymes + Prodigest. 

Peptiva Advanced Digestive Relief is a daily probiotic that apparently boosts your overall health. They ensure potency stays the same over time. The supplement also contains a “stress relief and calming matrix.” 

Peptiva + Sleep Support is a probiotic meant to be consumed at night. Apparently, this formula helps you gain digestive balance while you sleep. Valerian root and melatonin are also included to help you fall asleep faster. 

Peptiva Vegetarian Digestive Enzymes + Prodigest says it is an “advanced formula” that can help you get relief from boating and unpleasant gas. The formula contains 17 digestive enzymes and some herbs for maximum results. 


Peptiva Ingredients

Although Peptiva offers three different kinds of supplements, many of the bacteria strains and ingredients are the same. 

To gain a better understanding of how this product works to replenish healthy gut bacteria, we need to examine the ingredients in Peptiva, which include the following:

Lactobacillus Acidophilus

Also called L. acidophilus, this is a form of good bacteria and is the most commonly used probiotic. It assists by breaking down food in the intestine and restoring a healthy bacteria balance.

Bifidobacterium Bifidum

This is one of the most common probiotics found in humans and mammals. According to Frontiers in Endocrinology, Bifidobacterium bifidum helps by stimulating good/beneficial bacteria in the gut.

Bifidobacterium Animalis

Bifidobacterium animalis is found in the large intestines of humans and other mammals. It is also commonly found in fermented dairy products such as milk and yogurt. This bacteria may help relieve symptoms of constipation and other gastrointestinal issues.

Lactobacillus Rhamnosus

Lactobacillus rhamnosus is a probiotic strain often used in yogurt and dairy products, as well as supplements. It is a subspecies of L. casei, and helps prevent the growth of bad bacteria, and may help restore your gut.

Lactobacillus Paracasei

According to “The Microbiota in Gastrointestinal Pathophysiology,” this probiotic strain is often used to balance and restore normal gut flora. Lactobacillus paracasei is found in kefir and yogurt.

Gamma-Aminobutyric Acid

Some people take Gamma-Aminobutyric acid (GABA) to elevate mood and enhance sleep, according to Frontiers in Psychology

Valerian Root Extract

According to Acta Medica Portuguesa, valerian root may help you fall asleep faster and even improve sleep quality.


Melatonin is a hormone that is found naturally in the human body. It can also be made synthetically in a laboratory. It helps the body regulate its sleep and wake cycles.

The body produces more melatonin when it is dark, which gets the body ready for sleep.


According to the official website, “PRODIGEST® is a patented combination of 2 standardized ingredients: a lipophilic CO2 extract of ginger roots (Zingiber officinale Rosc.) and a unique extract of artichoke leaves (Cynara cardunculus L.) that has shown benefits for improved digestion, providing natural digestive relief.”

Does It Work?

Does Peptiva Work?

Peptiva contains six scientifically validated probiotic strains and a few herbal extracts supported by some clinical research.

Research published in the journal PLoS One concluded, melatonin has been shown to help with sleeping issues and may help you get to sleep more quickly, increase total sleep time, and enhance overall sleep quality.

According to the American Journal of Medicine, valerian root demonstrated positive effects on sleep quality and helping people get to sleep faster.

Gamma-Aminobutyric Acid or GABA has shown some positive effects on sleep quality and overall relaxation, says the Journal of Nutritional Science and Vitaminology.

Benefits & Results

Peptiva Benefits and Results

The Peptiva claimed benefits are simple – better digestive health, better sleep, and more healthy gut bacteria. This product contains no known allergens and is even considered vegan, so it does not contain any animal ingredients.

According to the website, you should feel calmer, more relaxed, less stressed, and enjoy deeper sleep after only 30 minutes of taking Peptiva.

In 8-12 weeks, you should notice reduced abdominal discomfort, less bloating, better regularity, and improved intestinal health and function, according to the manufacturers.

Weight Loss

Details on Peptiva and Weight Loss

Will this sleep support and digestive health supplement help you lose some weight? Let’s take a closer look.

A study in the Porto Biomedical Journal concluded the “probiotic effect in body weight is specific and strain-specific.”

According to the journal Nutrition & Metabolism, probiotics may help with the prevention and treatment of obesity.

Based on research presented in the journal Frontiers in Endocrinology, GABA might affect metabolic function, appetite, and activity levels, according to LiveStrong.

According to the Journal of Pineal Research, “melatonin limits obesity in rodents without affecting food intake and activity, suggesting a thermogenic effect.”


How to Take Peptiva

To use Peptiva, you need to take one capsule 30-60 minutes before bedtime. It can be taken with or without food.

Furthermore, this supplement can be taken daily to achieve maximum benefits. There is no special diet plan mentioned with Peptiva pills.

Also, each package of Peptiva has a shelf life of 18 months. This probiotics supplement should be stored in a cool, dry place, but does not require refrigeration.

Side Effects

Potential Peptiva Side Effects

While there’s no mention of side effects from Peptiva; there’s a chance some may notice side effects from Peptiva ingredients, including:

  • Headache
  • Upset stomach
  • Gas
  • Bloating

What About Peptiva Probiotic Reviews?

You can find several Peptiva reviews posted on the official website. There are also user comments and remarks for Peptiva posted on dealer websites such as Amazon and GNC.

This product received 4 out of 5 stars on Amazon and 4 out of 5 stars on GNC. Naturally, these ratings may change over time. We encourage you to read some of the customer feedback because it will give you better insight into what others have experienced while taking Peptiva capsules.

Results certainly vary from person to person.

Product Warnings

Peptiva Product Warnings

Always pay close attention to warnings that apply to any new products you consider. Here is a closer look at the Peptiva product warnings, according to the label:

  • Peptiva is for adult use only.
  • Peptiva may cause sleepiness and drowsiness.
  • Do not take Peptiva with alcohol.
  • Do not take Peptiva while driving or operating any heavy machinery.
  • If you are pregnant or nursing a child, consult a healthcare practitioner before using Peptiva.
  • If you have a serious medical condition, be sure to speak with a doctor before using Peptiva.
  • If you are already taking medication, you must consult your doctor before taking Peptiva.
  • Certain prescription drugs and medications may interact with probiotics.
  • This product is not intended for use on animals.
Where to Buy

Where Can You Buy Peptiva?

You can purchase this clinically validated probiotics and sleep support formula directly from the main website.

You can also buy Peptiva pills from dealers such as Amazon and GNC and a few other online distributors, including Gifts County, Bon Shoppe, and eBay.


Peptiva Cost

Since there are a couple of different products from Peptiva, prices will vary. 

Peptiva + Sleep Support costs $59.99 per package. It is available on GNC for the same price. If you have a one-time purchase on Amazon, the supplement costs $49.97, and a subscription costs $47.47. 

On the official website, Peptiva Advanced Digestive Relief costs $64.99. On Amazon, the supplement costs $49.99. 

Peptiva Vegetarian Digestive Enzymes + Prodigest costs $34.99 on the official website and GNC. You can also buy it for $29.99 on Amazon. 

Unfortunately, we did not find any Peptiva coupon offers online. However, the official website does mention that you can save up to 40%.


Peptiva Alternatives

You can find some alternatives to Peptiva online and in health supplement stores or drugstores. If you are specifically interested in supplements that contain probiotics and sleep aids, focus on products that use similar ingredients to Peptiva capsules.

Also, keep in mind that different products contain different ingredient portions. Therefore it is helpful to examine the supplement’s label to determine how much of each ingredient is used and how potent the formula is.

For those only interested in digestive support, there is Peptiva Advanced Digestive Relief. This is a little different from the Peptiva Plus Sleep Support formula.

It is still taken 30-60 minutes before bedtime but is not claimed to help with more restful sleep. However, it is claimed to do the following:

  • Replenish healthy gut bacteria
  • Alleviate bloating and discomfort
  • Help with irregularity
  • Promote relaxation and emotional well being

Again, you only need to take one pill each night, and it is also doctor-formulated. Peptiva Advanced Digestive Relief contains 50 billion active cultures, and the ingredients include:

  • Lactobacillus acidophilus
  • Bifidobacterium bifidum
  • Bifidobacterium animalis subsp. Lactis
  • Gamma-Aminobutyric Acid 100mg
  • Lemon Balm Extract 75mg
  • L-Theanine 200mg

This multi-strain probiotic blend also offers guaranteed potency and is said to restore digestive balance. It is available through online stores such as GNC and Amazon for $64.99 (30 capsules).

What Users Are Saying

What Users Are Saying

“It’s like a Miracle! – I have had stomach issues for years. Heartburn or too full feeling after meals. I used Tums, liquid antacid, the 14 day pump inhibitors. They might work temporarily and partially. But this stuff has made my stomach feel like it did years ago when I could eat anything. I have tried eating a bunch of stuff and no heartburn, no pain no issues. It’s working like a charm for me. To me, this is a gift from God! It’s like a Miracle!”

“I really liked this medicine, but the price is way too much for 30 day supply. Made me sleep, helped my tummy, too much money. I bought a comparable probiotic and a bottle of 10 mg melatonin and take the equivalent! Works just as well and cheaper.”

“I love the affect of Peptiva, but they smell awful.”

Bottom Line

The Bottom Line – Does Peptiva Work?

With clinically-backed ingredients to back up the claims made by Peptiva, we can’t deny that the product could be beneficial to your digestive health. It may even play a role in helping you sleep. However, when it comes to weight loss, it doesn’t seem like this product would be the one for you.

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Dietspotlight readers can take advantage of a free trial offer of Noom to see just what it feels like to have the support you need to lose weight and keep it off.

Learn More About Noom »
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What are the ingredients in Peptiva?

The ingredients in Peptiva include:

  • Lactobacillus acidophilus
  • Bifidobacterium bifidum
  • Bifidobacterium animalis subsp. lactis
  • Lactobacillus rhamnosus
  • Lactobacillus paracasei
  • Gamma-aminobutyric acid
  • Valerian root extract
  • Melatonin
What are the side effects of Peptiva?

The potential side effects of Peptiva, according to customer reviews we found, include: dizziness, headache, bloating, irritability, gas and stomach cramps.

Is Peptiva a good probiotic?

Peptiva claims to be clinically-validated, but there’s no proof to support that claim. They say it’s beneficial to take at night since your body naturally resets at night.

What is Peptiva good for?

Peptiva is a probiotic used to support digestive function. The ingredients claim to help you better balance your health while getting better sleep.

What is the sleep aid in Peptiva?

The sleep aids in Peptiva are melatonin and valerian root. Healthier gut bacteria may also help aid in sleep.

Where can I buy Peptiva?

Peptiva can be purchased using their Official Site.

How long does it take Peptiva to work?

It takes about 30 minutes for Peptiva to work. The company suggests using the product for 8-12 weeks to see results.

How do I contact Peptiva customer service?

Peptiva customer service is reachable via support@peptivaprobiotics.com.

Can I return Peptiva?

Yes, you can return Peptiva within 30 days of receipt.

What are the most common complaints about Peptiva?

The potential side effects of Peptiva, which are a major cause of discomfort are the most common complaints about this product.

18 Peptiva Reviews

  • I think there IS a weight control benefit
    Robert Chambers (Verified Purchase)

    I’ve been using Peptiva for about six months. Previously, I used Floramor. I’ve been quite impressed with Peptiva on the sleep assist and digestive regularity fronts. I decided to Google it to see if there were any weight control claims associated with it as I was unaware of any, previously. I’m an older athlete and I typically gain weight over the winter. That hasn’t happened this year and I believe the reason is the Peptiva and how thoroughly cleansed I feel all the time now.

  • Ann Crane

    Is peptiva safe to take with high blood pressure?

    • Angelica Almaraz

      Hello Ann,

      We recommend consulting with your physician before using any supplements that may conflict with any medical issues.

  • Greed in America2

    With all of these side effects you WILL CERTAINLY are going to sleep better!

    Stomach cramps

  • It works! Try it for yourself
    Patrick Paules (Verified Purchase)

    Peptiva works great without any side effects or waking up groggy. I am on a fixed income and can not afford the price of this product. However, you get the option to buy an extra box for $5.99. It is worth it.

    I have tinnitus and it is difficult falling asleep. I also have problems staying asleep because of a debilitating injuries I sustained to my spine. Without going into my problems this product works. Try the sample and you will also finally find the rest that has been missing from your life.

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