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Wegovy Review - 14 Things You Need to Know

Wegovy – a prescription-based medication is based on an ingredient initially released to help regulate blood sugar levels. Now, it’s taking the world by storm as a weight-loss solution. 

Our research team read hours of research on Wegovy and semaglutide before combining everything they found here. Check out the bottom line on Wegovy today!

Wegovy can be purchased through their Official Site.

Wegovy Readers: Noom is offering our readers a risk-free trial, for a limited time. Click here for more information!

What is Wegovy for Weight Loss?

what is wegovy

An injectable medicine available by prescription only, Wegovy is designed for adults suffering from obesity or chronic excess weight. It is specifically formulated for adults who are impaired by such issues as blood sugar problems that affect weight loss, as well as physical issues that make it difficult to keep off weight.

  • Journal of Investigative Medicine – clinical trials of Wegovy (also known as semaglutide) demonstrated high success rates when compared with placebo and other similar medications for weight loss. These successful trials led to FDA approval of Wegovy for medically-related weight loss.
  • New England Journal of Medicine – has published research that proved sustained and clinically on-target bodyweight reduction in adults.
  • Diabetes, Obesity and Metabolism – research claims Wegovy is the very first oral T2D medication that has been fully approved for clinical use due to successful clinical trials. Wegovy weight loss has also been effectively tested in young patients that range from the age of 3.5 years to 15 years.

Wegovy Competitors

Ozempic Weight Loss
Belviq Weight Loss
Calibrate Weight Loss

Who Makes Prescription Wegovy?

Novo Nordisk is the maker of Wegovy and is responsible for Wegovy availability. The company was developed when two small Denmark companies merged in 1989 to produce and distribute a medication discovered by two Canadian scientists in the early 1920’s.

Existing to fight blood sugar issues and other chronic illnesses, Novo Nordisk’s main goals are to further develop, create and improve scientific and medical breakthroughs.

Novo has a Better Business Bureau (BBB) file, but they aren’t accredited by the organization. The current rating is a C-, though a second BBB file for the company exists with an A- rating.

Reaching Wegovy Customer Service

Novo Nordisk’s customer service department is easy to reach, as well as responsive. For product inquiries simply call 1-800-727-6500. You can also fill out and submit a detailed form and the customer service folks will get back to you promptly.

If you need assistance or advice regarding the Wegovy cost, please visit Novocare.com or call the Novo Nordisk customer service phone number related to your specific medication need.

Other Products From the Makers of Wegovy

Aside from the new and advanced Wegovy medication, Novo Nordisk also produces and distributes other superior blood sugar-level maintenance products such as pen needles, alternative chronic weight management meds, biopharmaceuticals, and more.

Be aware that due to the success and popularity, there are often Wegovy shortage time periods.


Wegovy Claims to Do What?

wegovy claims

An injectable prescription medication, the company that produces Wegovy (semaglutide) claims that the medicine reduces obesity and weight gain in people with weight-related medical problems.

Novo Nordisk further claims that Wegovy not only helps T2D and other chronically ill patients with weight issues to lose weight but also is able to keep the weight off.


Wegovy Ingredients: What’s Inside?

Every Wegovy single-dose injection pen is pre-filled and contains 2.4 mL of semaglutide.

Each 1 mL of Wegovy also includes the following inactive ingredients: 1.42 mg of disodium phosphate dihydrate; 8.25 mg of sodium chloride; and water.


Does Wegovy Work? Wegovy Benefits

Wegovy contains semaglutide, which is an FDA-approved human GLP-1 receptor agonist turned weight-loss shot but does it work?

When dietary and physical activity counseling were combined in a 52-week trial, Wegovy was a success and showed important clinical weight loss compared with various placebos at various doses, according to the journal Lancet.

According to the FDA, Wegovy is the first weight-loss treatment approved by them since 2014. The medication has been called a game-changer again and again when it comes to weight loss for those with blood sugar problems and other chronic illnesses.

How Does it Work?

How Does Wegovy Work?

how does wegovy work

Wegovy imitates a human hormone named glucagon-like peptide-1 (GLP-1), which targets areas of the brain that control appetite and the intake of food. Subjects who tested the drug lost up to 20% of their weight!

But taking an injection of medication alone will not bring on successful weight loss. The people who lost and kept off weight also followed a program of exercise and nutritious eating.

It comes down to this fact: For adults suffering from obesity and overweight, semaglutide 2.4 mg once a week has been proven to give those who need it a clinically superior decrease in body weight compared to a placebo, according to research published in the Lancet.

Weight Loss

Wegovy and Weight Loss: Science Speaks Volumes

Wegovy weight loss research write-ups indicate that semaglutide, the main ingredient, has the capability of improving weight control. This is because, both in clinical trials and in prescription use, Wegovy has provided more weight loss effects for those with blood sugar issues than any past medicines thanks to the ingredient’s link to metabolism improvement.

According to the FDA, the treatment was approved only for people with at least one weight-related condition. These can include increased blood pressure, increased cholesterol and blood sugar problems. They go on to say that Wegovy shouldn’t be used in conjunction with any other weight-loss products or prescriptions, including herbal and over-the-counter options.

Now, let’s look at how much weight people lost using the Wegovy injection. 

The New England Journal of Medicine shares research that shows about a 15% reduction in weight after study participants used Wegovy for 68 weeks or 16 months. The placebo group only lost 2.4% of body weight. That 15% accounts for more than 33 pounds lost versus about 6 pounds for the placebo participants.

But, it doesn’t always take that long to see weight loss. In a Phase 4 study published in the JAMA, people using Wegovy lost around 11% of their body weight in just 20 weeks. When the study group was split with some people staying on the medication for another 48 weeks and others being switched to a placebo, it was found that weight loss continues as you continue Wegovy use. The placebo group gained weight.

Side Effects

Wegovy Side Effects You Need to Know

wegovy side effects

When taking Wegovy the following side effects can be experienced:

  • Injection site pain and redness
  • Feelings of nausea
  • Diarrhea and/or constipation
  • Headaches
  • Fatigue
  • Upset stomach
  • Dizziness
  • Bloated feeling
  • Burping and gas
  • Heartburn

In order to reduce the chances of side effects, Wegovy is titrated to the 2.4 mg dose. This means the user starts out at a much smaller dose and works up to the full dose over time. Check out the next section to see how titration works.

How to Use

How to Use Wegovy?

Wegovy should be used by following this specific dosing chart:

Titration Chart:

Month 1: Begin use at the dose of 0.25 mg per week.

Month 2: Up the weekly dose to 0.5 mg.

Month 3: Increase the weekly dose to 1 mg.

Month 4: Up your weekly dose to 1.7 mg.

Month 5: Upon the 5th month and beyond, your dose is increased to 2.4 mg, which is the medication’s full strength.

Cost and Where to Buy

cost and where to buy wegovy

Novo Nordisk offers two ways for you to discover your coverage and estimated cost. A trained NovoCare representative will talk you through the cost and coverage paths, as well as explain any of your eligible benefits.

Call or fill out an online form for the responses to the questions you have.

Call: 1-888-809-3942 Monday-Friday, 8:00am-8:00pm ET

Online Form: 24 hours a day, 7 days a week. Please ensure you have the necessary information on your prescription insurance card if you have one.

Wegovy Coupons, Discounts, and Promo Codes

The Wegovy price is steep at approximately $1,400 for a 2 ml supply.

Wegovy is currently available as a brand-name drug only. A generic version won’t be available for years while Novo Nordisk holds the patent. For cost support, find a Wegovy savings card online – part of their WeGoTogether support system.

Pros and Cons

Pros and Cons


  • Scientists and doctors, along with Wegovy weight loss reviews, have amazing things to say about semaglutide.
  • It’s been called a “game-changer” that could alter the face of obesity issues.
  • The prescription has helped people with blood sugar issues lose considerably more weight than past medications.
  • It appears to work on parts of human biology linked to obesity, such as metabolism.


  • There may be side effects including diarrhea, bloating, gas, and heartburn.
  • If insurance doesn’t cover Wegovy, you could spend nearly $1500 a month.
  • Gastrointestinal side effects were reported in the majority of trial participants.
Bottom Line

What Users Are Saying

“I am currently on my 9th injection today, being my 8th full week being on Wegovy. I have lost a total of 40 pounds so far. Appetite is definitely curbed. Sunday’s when I take the injection and it makes me tired. A lot of gas and the occasional runs, but the weight loss is worth the side effects.”

“I think what causes weight loss is the nausea. I’m literally afraid to eat while taking this. The heartburn is like nothing I’ve ever experienced and now I’m on the 2.4 dose and have decided I am DONE. I will not punish myself anymore with this drug. On this dose I feel nauseous, dizzy, and exhausted as well as the horrid heartburn.”

Bottom Line on Wegovy Results

Prescription-only, FDA-approved Wegovy continues to help folks suffering from blood sugar issues and other chronic illnesses that make it difficult to lose and keep off weight.

While it may come with side effects like gas, bloating and headaches, Wegovy has been a success. The basic reason why: the way the medication copies glucagon-like peptide-1 (GLP-1) which controls appetite and food intake.

If a prescription solution is not for you, take a look at the best weight-loss program we’ve come across in years – Noom. Noom is recognized as a CDC-supported healthy living program, reviews are amazing and people lose weight in a way that lasts. Special features include a real-life coach and dedicated support group for every user, up-to-date lessons and education and more.

We’ve partnered with Noom for a limited time so all Dietspotlight readers can take advantage of a free trial offer.

Learn More About Noom »
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5 Wegovy Reviews

  • Amazingly quick weight loss, but side effects can be intense.
    Mary (Verified Purchase)

    I lost 47 lbs in 6 months on Wegovy, but I’ve had a LOT of nausea, which has drastically affected my caloric intake. I’ve also developed a number of food aversions since I started taking it. I’m concerned about malnourishment because I know the mechanism by which this drug works by tripping the satiety switch and slowing digestion so you feel fuller for longer, and on less food. It’s not meant to work by making you sick to your stomach all the time. That’s a side effect, and in my case, it feels like I lost all of this weight because I’ve been in starvation mode. There are days when all I can gag down is a banana and a package of ramen. There are days when I feel normal, too, but the nausea can be rough.

    I’ve also been experiencing severe muscle weakness. I believe it’s due to the Wegovy because my pharmacy was out of stock for an entire month, and during that time, I began to feel stronger and more like myself. I’ve been back on it for 5 or 6 weeks now, and today, I had to put air in the tires, which meant squatting and then standing up 4X. By the time I finished the last tire, my legs were so weak, I couldn’t stand up again without grabbing onto the car.

    That said, I’m so thankful for the weight loss, and I hope to lose more, but not by feeling weak and sick all the time. I think that there are probably a lot of people who’d stop taking it if they felt this bad on it, but I’m desperate. I might ask the doctor if lowering the dose might alleviate some of the misery, while still enabling further weight loss. There’s got to be a happy medium!

  • Wegovy saved my life
    Crystal H (Verified Purchase)

    Started Wegovy on 10/2/21 at 313lbs. As of 8/29/22 I am down 100lbs with no exercise. I experienced very little side effects!

  • Very effective for me
    Joy Albrecht (Verified Purchase)

    I started Wegovy around 13 weeks ago and have lost 26 pounds. I am thrilled with it as a tool. I have read a lot of complaints that people have not lost weight but in my honest opinion, most are probably because they are not in the right mindset. It is so hard to listen to the ‘full’ cues that Wegovy gives you when you are used to eating so much more. If you overcome the emotional addiction to food this medication will work wonders. I feel so much better, a lot more energy and looking better than a long time. My only side effect is heartburn the first 2 days after injection day but I use a heating pad at night and tums during the day. The cost is hard of course but it is worth it to me. I am hoping to loose another 40 pounds by the time I hit the 12 month mark and I will be at my target weight.

  • Ed (Verified Purchase)

    This is an amazing product for weight loss. Since 1/1/22 until now 3/24/22 I dropped from 260 to 236 19 lbs. I walk 3 miles a day, use the Wegovy coach and eat far less. I was raised as a clean plate guy but now I leave food on my plate because I am full. I have tried every other weight loss program with short term success. I cannot tolerate stimulant type drugs. At worse I have some mild nausea *reminds me to eat less) and feel bloated (eat less).

  • E. Cartman

    Insurance will NOT pay for it, manufacturer discount reduced price by $200, leaving a balance of $1100. They market this drug and get everyone excited about only to find out one must forego their mortgage payments to afford it. Insurance would rather you have invasive bariatric surgery which would cost the same by comparison over one year. The system is broken!

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