Updated: 05/17/2016 - Website operated by Leptigen

Isotonix Review - Does This Wellness Supplement System Work? Are cost and inconvenience deal breakers?

Editor's Review: 3.5 / 5.0
Isotonix  Review

97% of dieters just want a product that works. Yeah, we don’t understand that remaining 3%, either. Powders are a trendy item when it comes to supplements, because of the growing popularity, we did one of our reviews, taking an in-depth look at the ingredients, side effects, supporting scientific research and customer service. We also dove deep into hundreds of user comments and experiences to find the facts. Then, we summarized and refined to give you the info you need.

EDITOR'S TIP: Combine Isotonix with a proven fat burner such as Leptigen for better results.

What You Need to Know

Firstly, Isotonix comes in a powder form and is designed to be mixed with water or your favorite beverage. The company offers a wide variety of multivitamins, wellness supplements and weight-loss products. The bottles are small enough to take on the go, but you have to mix with liquid, so that can make it a bit inconvenient.

Isotonix has been around for over 10 years. This longevity in the weight-loss industry is a positive indication. The products are readily available online and the risk of side effects is minimal, as long as you aren’t allergic to any of the ingredients. We also like that they have supplements geared towards just about every age group, but read on…

Price – “Wowsers?”

The first issue we came across with Isotonix ingredients was price. While it seems affordable at first glance, it’s much more expensive than a daily multivitamin or wellness supplement that you could get at the drug store. “Isotonix isn’t prohibitively expensive,” said our Research Editor. “But compared to similar products, it’s more than double the price for the same ones in tablet form.”

“Before I realized it, I had $300 worth of Isotonix products,” said one user.

“These…seem to do the trick, but is it really that different than what I can get at Walgreens?,” said another.

Inconvenience – “Concerning?”

One other complaint that many people have pertains to the powders as an inconvenience. “I’ve been taking Isotonix for a month now, but I miss at least one day a week because [they] are so inconvenient,” said one customer.

“These seem to work when I can get the mix right, but that’s only about half the time,” offers another.

“I hope I’m getting the mixture right, but I’m not seeing any results,” explains one frustrated reviewer.

Throughout our research into today’s diet and wellness supplements, we’ve seen that whenever there is something that is more difficult or troublesome than necessary (painful exercise, side effects, cost, inconvenience, etc.), the likelihood of losing weight and improving your lifestyle long-term are slim. If Isotonix really is inconvenient and more expensive than alternatives, this could be an issue.

The Science – “Clinical Proof?”

Some of the Isotonix products are well-researched and proven to help with weight-loss. Unfortunately these same ingredients are in the supplements that you can find at a fraction of the cost on the shelves in any grocery or drug store. These do have the benefit of taking effect faster, but that benefit isn’t worth paying double for. Here at DietSpotlight, in order to recommend something it must be better than more affordable alternatives and proven in clinical studies. When you’re paying more for something that offers similar results, we lean toward the cheaper alternative.

The Bottom Line – Does Isotonix Work?

So, the last of the facts have trickled in. What’s our take on this one? We like the fact that Isotonix has been on the market for over 10 years and that it seems to have developed a cult-like following. We also like the results that some users have seen and that the product is readily available, but we have reservations recommending this because of the more affordable alternatives on the market that accomplish the exact results. We’re also concerned about the inconvenience of mixing the powders.

If you’d like a convenient, affordable way to lose, we suggest a supplement that provides healthy and steady weight-loss with a formula that has ingredients backed by published research and trials. We also suggest you find a product that doesn’t have cheaper alternatives that provide the same benefits.

Among the best products we’ve seen in 2016 is one called Leptigen. This proprietary blend of four ingredients has been clinically proven to help boost weight-loss by promoting metabolism and fat loss. The supplement has not led to any adverse side effects and users online seem happy with the results that they’ve seen.

Right now, the makers of Leptigen are standing behind their product with a Special Trial Offer, which shows just how confident they are that you’ll love the supplement.

Learn More About Leptigen »
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How Does Isotonix Compare?

Previous Isotonix Review (Updated October 3, 2014):

What You Should Know

Click Here To See Our Highest Rated Review

Isotonix is a line of health and wellness supplements produced by the Market America brand. With several different products, ranging from multi-vitamins to weight management and anti-aging, this company is targeted at anyone who has health concerns, and has the products to address them. Sort of like Qivana, even though Qivana is an MLM company. Some products are based in chromium like Biocitrin. Read this review to learn more about their products and how they may be able to help you reach your weight loss goals.

List of Ingredients

Isotonix produces several different health and wellness supplements. The ingredients will vary depending on which product you buy. We suggest you take a closer look at the supplement ingredients on the product or products you are interested in.

Product Features

Isotonix products include: Anti-Aging, Antioxidants, Blood Sugar Maintenance, Bone & Joint, Digestive Health, Family Health, General Health, Heart Health, Sports Nutrition, Skin Health and Weight Management. In this respect, striking similarities can be drawn between Isotonix and Organo Gold products that also have varied effects. The products average about $40 each for a month’s supply, but each purchase earns you a small amount of customer loyalty currency to help you get discounts on later purchases. The weight management product is called Isotonix IsoChrome, and its main ingredient is chromium, which has been shown in clinically studies to help stabilize blood sugar levels in much the same way Mulberry leaf does in Slim Xtreme Gold. Stabilized blood sugar levels not only helps with diabetics, but it can keep those with normal blood sugar levels from having too many cravings or feeling too hungry when they are not.

See Our Featured


  • Isotonix comes in liquid forms that allows for faster absorption by the body.
  • There are products to address various types of health concerns.


  • Isotonix products are more expensive than most multivitamins.
  • We can’t see full ingredient listings.
  • This product involves mixing, and if you mix it incorrectly, it may not work as effectively.
  • There are no dietary recommendations to support these products.
  • There are no exercise recommendations to support these products.
  • Many of their products are supported by mixed reviews.


Isotonix products cater to a wide variety of health needs. Isotonix IsoChrome is similar to many others chromium based weight loss products on the market today, except that it is available in liquid form while the others are some sort of pill, be they capsule or tablet. With the hassle of having to correctly mix the liquid, you can save money, time and frustration by choosing another one of those products. However, chromium alone is not going to be the answer to your weight loss journey. As with Prevagen certain ingredients just don't do it all. For any weight loss supplement to be effective, it needs to be clinically proven as such, and taken as directed. It should also be combined with a nutritionally balanced, slightly reduced calorie diet. It should also be used with a regular exercise routine that involves both cardiovascular exercise.

Isotonix Questions & Answers:

We picked apart hundreds of user comments about Isotonix and condensed into this helpful FAQ.

What are the side effects of Isotonix?

Isotonix side effects may include headaches, dizziness and lack of focus, as mentioned in some customer reviews.

What are the ingredients in Isotonix?

Isotonix ingredients are chromium, l-carnitine, pycnogenol, resveratrol, acai, coenzyme Q10, vitamins, minerals and lutein. The formulas differ depending on the supplement.

Does Isotonix work?

There are no scientific studies linking Isotonix to weight-loss. We did find research into some active ingredients, like chromium, but that ingredient is used in other products. Also, there’s no clinical research proving acai is anything more than a “fad”.

You may want to rethink things and replace Isotonix with a clinically tested supplement like Leptigen.

How much does Isotonix cost?

Isotonix costs vary by supplement. The weight-loss supplement costs $41.95.

How should I take Isotonix?

You should take Isotonix based on the supplement purchased.

Can I take Isotonix if I have a health condition?

If you take prescription medications of any kind, those with health conditions, anyone under 18 years of age or women who are pregnant or nursing should consult with a healthcare professional prior to using weight-loss supplements, including Isotonix.

What do users like about Isotonix?

Some users liked that Isotonix supplements were available on the official website and that several of the products contained natural ingredients.

What do users NOT like about Isotonix?

We found that some users didn’t like that the Isotonix customer service department was difficult to reach and that the supplement didn’t help with weight-loss.

How do I contact the Isotonix customer service department?

You can contact the Isotonix customer service department by sending letters to Market America 1302 Pleasant Ridge Rd. Greensboro, NC 27409, calling a representative at 1-866-420-1709 or emailing info@marketamerica.com.

When is the best time to take Isotonix digestive powder?

The best time to take Isotonix digestive powder is in the morning.

Do Isotonix products contain soy?

Yes, several of the Isotonix products contain soy.

Does Isotonix come with a guarantee?

Isotonix comes with a guarantee. You will need to contact the customer service department, receive a return authorization and send the unopened item back for a full refund.

Do you know of any special deals or discounts on Isotonix?

There are special deals and discounts on Isotonix. If you order more than $99 worth of products, you will receive free shipping. However, the last few months have been buzzing with our readers taking advantage of Leptigen’s Special Trial Offer, which is just the cost of shipping and handling. Click here to give it a try.

23 User Reviews About Isotonix

Leave comments below
  • 1
    Your NameHEATHER



  • 2

    I was wondering if anyone has taken the activated B Complex, and if so did they have side effects, or any negative issues?


    Stephen (Editor)

    Anyone had good results?


  • 3
    Mike Thanasoulis

    I v e been taking this for close to ten years along with the acai.I was told by Dr. to sop taking the Acai because of the Chromium/Cobalt in it.I have high levels in the blood due to Metal on Metal hip replacements.My Question is does the OPC3 have any Cobalt or Chromium in it? I would like to keep taking it.I do miss the Acai.And would like to continue taking the OPC3. But not if it Contains Cobalt or Chromium.Thank You


    Stephen (Editor)

    It seems the formulation consist of Natural fruit extracts and flavonoids; no mention of metals like cobalt or Chromium, Mike!


  • 4

    do any of your products contsin soy?


    Karen (Editor)

    Hi Milly. From what we’ve found no however they do have a several many products.


  • 5

    Are Isotonix supplements safe for diabetics? I take Ultimate Longevity Formula and Maximum ORAC. They both VERY sweet.
    Ultimate Longevity formula contains soy. Soy is not organic,is it?


    Karen (Editor)

    Hi Joanna. If by “organic” you meant grown without dangerous pesticides, we cannot unfortunately say that this is or is not the case at this time.


  • 6
    Michelle Romaniszyn

    Hello. I recently sat in on a presentation on Isotonix Opc-3 and is benefits on your health as well as nutritional supplements and other products. My question is, Is this really a good product and are there any severe side affects. I don’t want to spend alot of money on something that isnt any different from another detox system. I am looking to detox my body, rather cleanse my body of toxins. I’ve never had a cleaning done before. What are your thoughts?


  • 7

    Isotonix was recommended to me and I’ve been doing some research on the product, but still have questions. I’ve suffered from acid reflux for quite some time, but lately, it was gotten really bad. One doctor thinks it could be the start of an ulcer and wants me to have an upper GI endoscopy. However, before opting you have then shoe a camera down my throat, I’d like to try Isotonix, as I’ve read excellent reviews about the product. My question is though, which one works best for acid refux..the digestive health or the OPC-3? I’ve also read about people taking the OPC-3 along with aloe vera juice. There are so many choices, I don’t know which one to go with. Please help me!! I need relief asap.



    Hello, I was introduced to opc3 3 years go because of acid reflux any food I eat will have a burning like feeling. I started taking it after one week I didn’t feel the burning in my chest.Awesome but it didn’t stop there I was sleeping better. I feel great. It help me so much I am happy.
    Isotonix .



    Full disclosure here: I sell Isotonix.. but only after taking OPC-3 for a few months and finally getting off the allergy meds I had used since I was a teenager. Since then, they’ve helped my mom reduce her high-blood pressure meds, helped my husband with joint pain, helped a friend with acid reflux and countless other benefits as a natural anti-inflammatory. I think it is expensive – but you get what you pay for – they have 3rd party quality control which means that you can trust what is on the label is IN the bottle…. (not true for MANY other companies (did you watch the Frontline piece out in Jan? Yikes.)


  • 8
    John Blue

    When is the best time of day to Isotonix digestive powder.



    If you’re referring to the digestive enzymes, take it after having a meal.


    Your Name

    Opc-3 is supposed be taken 1/2 hour BEFORE YOU EATTell us your thoughts about Isotonix .


  • 9
    Janet Lee

    May I know is weight increase a side effect after taking isotonix. I have started for about 2 months. Tks



    The products provide supplemental nutrients, there are no side effects.


  • 10
    William Thompson

    I committed to myself and my wife to lose weight and take the Isotonixs she purchased for me. However, after taking this stuff for several days, I had to quit. I agreed to continue the diet, but each time I took this stuff, I felt a lot of pressure in my head, couldn’t focus my thoughts, felt dizzy, and my vision went somewhat out of focus. So much for Market America. I wish she could receive a refund. She spent several hundred dollars.



    What products are you taking, what portion sizes are you taking and how does your wife feel when she takes the products? If you are by any chance allergic to a product you can get a bad reaction such as what you’re describing and it doesn’t mean the product is bad since no one else is having the same reaction. The products are made from natural fruit, and vegetable extracts but some people do have food allergies so your claim cannot be discounted, the solution is to determine what you’re reacting to.


  • 11

    Are there any side effects from taking these vitamins?



    The products provide supplemental nutrients, there are no side effects because all the ingredients are natural extracts from fruits, vegetables and certain tree barks rather than chemical based pharmaceuticals that have various side effects.



    What’s up with the Fructose and Glucose in the product? I must admit the product works for weight loss but I’m concerned about those two chemicals especially…..


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