People are talking about Isagenix, so we thought it a good idea to take a closer look into the ingredients used by the company, possible side effects, clinical studies and customer service. We read user comments from hundreds of dieters all over the web. We took this information, summarized and compacted to give you the bottom line.
What Is Isagenix?
To start, Isagenix is a supplement company offering weight-loss solutions. Products include meal replacement shakes , formulas to flush toxins from the body and energy boosters (caffeine)  There are supposedly no laxatives used in any cleansing formula, which is a good thing because misuse of laxatives  can cause side effects . Some are taken in the morning and others at night. One good thing is that we found some ingredients with impressive clinical support, which is not something we can say about every product we encounter.
The products, introduced to the market around 2002, appear to contain all-natural ingredients, which is always good but it doesn’t necessarily mean they are free for any negative potential . Isagenix is available by phone and from marketing associates. We like the good BBB rating and the company has been in business for more than 13 years, but read on…
The Cost of Isagenix – “Over the Top?”
The first concern is the prices associated with Isagenix products. “You can’t put a price tag on weight-loss, but there’s a problem when a company charges two or three times that of others,” said our Research Editor. “You can purchase the 30-day weight-loss program for around $350.”
“I should have listened to my smarter side before dishing out close to $400 for this product, but I’m only human and fell for the empty promises [which is a problem with multiple companies]  that their website offered,” according to one customer.
Another dieter said, “This is an very small jar for the very high price.” This was a complaint from multiple people who chose to buy Isagenix products.
We do have to keep in mind that a high cost to some is not expensive to another, according to several Isagenix reviews.
As one buyer says, “Great price/Great product.”
Another stated, “My favorite way to start the day and price is approximately equal to other protein shakes.”
Buyer Reviews – “Not Good”
According to Isagenix reviews, customers complained about taste, cost, Isagenix side effects and a host of other issues. “All of this stuff tastes nasty. Like a big glass of grape cough syrup,” offers one dieter.
“I didn’t like it. It made me feel nasty. It wasn’t what I expected. Didn’t work for me,” claims a customer.
Just because there are negative comments doesn’t mean that reviews of Isagenix aren’t positive.
“It just becomes a way of life…a healthy way of life,” says one user.
Another offers, “I have had success with weight loss and feeling better with these products.”
In our research, we’ve found a strong connection between the small things, like poor customer experience or high price, and a negative effect on long-term success. If Isagenix fails the dieter in any way, that’s a red flag.
The Science – “Evidence to Back the Products?”
Isagenix offers some strong marketing materials, but selling a product is about more than convincing a reader to buy. We look for science and there’s just nothing on the official website. However, we know from research published in peer-reviewed journals, that meal replacements , especially those high in protein and fiber  , can work to curb appetite by slowing the digestive process . We see the addition of whey, but fiber doesn’t appear to be something the formulas are enriched with. Taking a look at the supplements in the line, you have green tea extract and cayenne . Both have shown promise in terms of facilitating weight loss through increased metabolism.Also: read our Leptigen Weight-Loss Kit review »
The Bottom Line – Does Isagenix Work?
Has the time come to sprint out for these products? The Isagenix company has longevity on its side and a supportive customer service department, but we have hesitations about recommending the supplements. The company doesn’t bother to share clinical research, though it does exist from testing in a petri dish to animals to humans. Everything is there for ingredients like whey protein and green tea extract. With that being said, just because the support is there doesn’t mean Isagenix products are stronger or better than the competition. That’s one place the business failed to sell us.
If the time has come to shed those extra pounds, we suggest a supplement with a formula packed with clinically tested ingredients, supported by strong customer reviews and backed by a company that goes the extra mile to give all the facts.
Among the best products we’ve seen this year is one called Leptigen. It’s made of a proprietary blend of four ingredients, clinically shown to help increase fat loss, accelerate metabolism and curb hunger. There’s no talk among customers of harmful side effects. Plus, we love the fact that customer reviews all over the web are taking about some impressive results.
The company responsible for Leptigen is confident enough to present customers with a Special Trial Offer – that’s a good sign.
Previous Isagenix Review (Updated June 5, 2014):
Isagenix Product Line - What You Should KnowIsagenix is marketed as a company that wants to impact world health, according to the Isagenix website. The company has a line of products for cleansing, nutrition, and skin care. One of the products in the cleansing line, Cleanse for Life, is advertised on other isagenix weight loss reviews as a tool for weight loss along with energy and good health. With their abundance of products you can find variations for different health solutions such as weight loss, snacks, cereals, energy and anti-aging. (Take a look at their wikipedia page if you'd like). Other companies that have similar product lines are Yoli Better Body System, Purium and Naturade. The bottles of Cleanse for Life are sold in a two pack, and each 32 ounce bottle is good for two cleansing days. This product appears to be recommended as a part of a complete system designed to cleanse your body over a 30 day stretch. It is also sold as part of the accelerated nine day program, which promises an average weight loss of seven pounds during that time frame. They also have meal replacement options, including shakes and soups. A similar meal replacement product is Prolessa Duo which is an appetite suppressant. The entire product line is available from the official Isagenix website, and also through a network of independent affiliate retailers similar to the classic Avon business model. We are pleased to see that the company provides complete ingredient lists for all of its products, but we are not so inclined to buy into the idea of a complete system with numerous products as the best weight loss method. It's nice to know Isagenix has a favorable BBB rating. We believe that many dieters can find success through a low calorie diet, daily exercise and a single, effective weight loss supplement. Incorporating an exercise routines like PiYo might help in the weight-loss process.
Ingredients in Isagenix ProductsThe ingredients in the berry flavored Cleanse for Life include a proprietary blend that contains aloe Vera leaf, IsaLyte trace minerals, Pau d'Arco inner bark, suma root, eleutherococcus senticosus root extract, burdock root, fennel seed, peppermint leaf, licorice root, choline bitartrate, inositol, betain HCL and I-methionine. We go over the Isagenix Ingredients in greater detail here. Another similar weight loss product that contains aloe vera is Calorad. By the way, it's interesting to view science produced by Isagenix themselves here. We do not see anything on this list that stands out as an effective weight loss supplement. While many of the ingredients may be quite healthy in other ways, we prefer to see an appetite suppressant like Slim Trim U or fat burners like Man Scorch on the list for maximum weight loss benefits. Well known weight loss substances like chromium, green tea, guarana and hoodia are noticeably absent from this list.
Product FeaturesSome of the Isagenix products appear to be quite pricey, although a double order of the Cleanse for Life sells for a reasonable $43 at the time of this review. We could not find any information about a free trial offer or money back guarantee.
The Advantages of Isagenix
- The idea of cleansing the body from the inside out does offer a number of health benefits.
- The company provides complete ingredient lists for its products.
The Disadvantages of Isagenix
- We could not find a money back guarantee.
- The product we looked at doesn't contain any proven weight loss ingredients.
- The product is sold as part of a complete package that includes many products and is quite expensive.
ConclusionWe like the idea of an effective cleansing product as a method of jump starting a diet. However, cleansing programs are rarely the best choice for long term weight loss. Another product that states that it cleanses the body is Diurex Water Pills. This particular product doesn't pack much in the way of proven weight loss ingredients to instill much confidence from us in its ability to help dieters shed excess weight. We encourage dieters to look for more effective formulas from other companies for best results.
Isagenix Questions & Answers:
We dug through hundreds of user comments and isagenix weight loss reviews, for us to be able to write this helpful FAQ.
What are the side effects of Isagenix?
Isagen, short for Isagenix side effects may include nausea and weight gain, according to some dieter experiences.
What is in Isagenix?
Isagenix ingredients including whey protein powder, stevia, psyllium , various vitamins and minerals, fruit extracts, green tea and apple cider vinegar.
What is the active ingredient in Isagenix?
The active ingredient in Isagenix is whey protein.
What is Isagenix 9 Day Cleanse?
Isagenix 9 Day Cleanse is a weight-loss / fat burning program that includes a meal replacement shake, snacks, fat burner and detox.
What is Isagenix 30 Day Cleanse?
The Isagenix 30 Day Cleanse is similar to the 9 day variety. There are a couple additional supplements and, of course, it lasts three times as long.
Does Isagen work?
The core of the Isagenix program is the meal replacement shakes. Clinical studies do show weight-loss is promoted when using these products.  But, there are quite a few supplements in the line and while some of the ingredients, like green tea extract, have good support, there’s nothing showing these formulas are better than less expensive alternatives.
How much does a bottle of Isagenix cost?
A bottle of Isagenix costs about $50 a week or $200 a month. The other supplements in the line come at an additional cost.
How do you take Isagenix?
You should take shakes up to twice daily. There are many supplements to choose from and each will have different directions. Typically you will take them one or two times a day.
Can I take Isagen if I have a health condition?
Any weight-loss supplement or program, including Isagenix, should be approved by your family physician. This is critical if you are pregnant, planning on becoming pregnant, nursing, taking medications of any kind, are under the age of 18 or have any medical conditions.
What do users like about Isagenix?
Users tend to like that the shake is easy to mix and take on the go. Some even liked the taste.
What do users NOT like about Isagenix?
On the opposite end of the spectrum, some users did not like the taste of Isagenix shakes at all. There are also complaints about high price.
Can I use Isagenix if I am lactose intolerant?
It may not be the best idea to use Isagenix shakes if you are intolerant to lactose, as they contain milk-based ingredients.
Do I have to use a blender with Isagenix shakes?
No, you do not need to use a blender with Isagenix shakes, but you will find the end result is smoother with fewer clumps, in some cases.
Who makes Isagenix?
The makers of Isagen is Isagenix Worldwide Headquarters.
How do I contact Isagenix customer service?
You can call Isagenix customer service at 1-800-877-8111 or 1-480-889-5777 between the hours of 5 am to 6 pm Monday to Friday or 6 am to 2:30 pm Saturday and Sunday. We also found a contact form and email address on the official website.
Can I contact Isagenix through social media?
There are good supplements out there that offer some support for weight-loss, but our research is to find products that offer more than that. Formulas like the one used in Leptigen give you more than many others on the market.
- 1. The right fiber for the right disease: An update on the psyllium seed husk and the metabolic syndrome (2010). Journal of Clinical Gastroenterology. October 1, 2015.
- 2. Weight management using a meal replacement strategy: meta and pooling analysis from six studies. (2003). International Journal of Obesity and Related Metabolic Disorders: Journal of the International Society for the Study of Obesity. May 27, 2016.
Isagenix User Tips:
Isagenix is a supplement company that’s known for weight-loss options. Reviews for the 9-day cleanse and 30-day program are all over the web. Among the comments and experiences are a few user tips here and there.
“This program doesn’t require you to stay an Isagenix user, but it does require you to change your lifestyle.” Madison
“The shake was palatable, I’d even go so far as to say it’s pretty good, just make sure you blend it with ice.” Erin
“Remember to continue strong everyday or you will fall through.” Keyla
“It is a commitment. You have to want to do it for it to work.” Tiffany
“This isnt a magical diet you need to work after to keep the results. Don’t trick yourself and fall back into old habits. You need to change your lifestyle.” Stephanie
“If you have medical issues, research the true ingredients, and like anything, consult your physician.” Justin
“Drink all the water you can (it really helps with the hunger pains).” Garrett
“The key to the program is counting calories.” Sergey
“Not a magic wand and you do have to follow the program.” Dawn
“I suggest if you are an unmotivated person who doesn’t like exercise and is looking for a miracle, then forget it.” Jaimee
Isagenix Scientific Abstracts:
Whey Protein Concentrate
Studies have indicated that the intake of dairy products is inversely related to a lower risk of cardiovascular diseases and metabolic disorders. Whey protein seemed to trigger the effects due to bioactive compounds such as immunoglobulins, glutamine, lactoferrin, and lactalbumin. Also, it’s a great source of branch chained amino acids. Upon further analysis from multiple reports, whey protein had appeared to contain a blood glucose and insulin suppressing effect partly mediated by incretins. It was concluded that whey proteins could affect muscle protein synthesis and glucose metabolism. The evidence shown in the clinical trials are not reliable enough to make any final recommendations due to a particular dosage and the duration of supplement. 
Rhodiola Root Extract
A study published showing the effects of Rhodiola in patients suffering from mild to moderate depression. In the participants involved, overall depression, emotional stability, insomnia, and somatization had improved significantly, while those who took the placebo had shown no signs of improvement. There were no adverse side effects reported in the trials, concluding standardized extract SHR-5 had shown anti-depression potency in individuals with mild to moderate depression when dosed with either 340 mg/day or 680 mg/day over a period of six weeks. 
The digestion, metabolism, and absorption of fructose differ from glucose. Unlike glucose, fructose doesn’t trigger insulin secretion nor does it enhance leptin production. Since both leptin and insulin act as important factors in the regulation of body weight and food intake, it’s suggested that dietary fructose may be a contributing factor towards increased energy intake and weight gain. 
Milk Protein Concentrate
There are reports of epidemiological evidence revealing intake of dairy products being associated with the decreased prevalence of metabolic related disorders. However, there is evidence from studies showing dairy protein as a dietary function aiding in the prevention of type-2 diabetes. Dairy protein may indirectly increase metabolic health by helping weight-loss and reducing fat mass via enhanced satiety, all while improving skeletal muscle growth and performance through the anabolic effects of BCAAs (branch chain amino acids). These amino acids are shown to enhance lean body mass, skeletal muscle function, and muscle protein synthesis. It was also shown that the composition and processing of dairy protein had a direct impact on the digestion process, concluding that dairy protein in milk may possess ways to maximize benefits for metabolic health. 
- 1. Effects of whey protein supplements on metabolism: evidence from human intervention studies (2011). Current Opinion in Clinical Nutrition and Metabolic Care. October 16, 2016.
- 2. Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression (2007). Nordic Journal of Psychiatry. October 16, 2016.
- 3. Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity (2004). The American Journal of Clinical Nutrition. October 16, 2016.
- 4. Milk protein for improved metabolic health: a review of the evidence (2013). Nutrition & Metabolism. October 16, 2016.
Isagenix Side Effects:
When you think of natural solutions and weight-loss supplements you need to understand the two aren’t always synonymous with no side effects. There is always a possibility for adverse reactions with any formula, although Isagenix side effects are pretty uncommon, with each individual person comes a different set of tolerances.
Stomach aches or pains are typically swelling or irritation in the stomach or abdomen region. They can range from dull to severe and be caused by a number of factors.
What causes stomach aches?
Causes can be something as simple as eating the wrong food, or a food item that doesn’t agree with your stomach. It can be caused by stress or anxiety, or an outlying condition such as gall stones or pelvic inflammatory disease, though rare. 
Vomiting is the forced expulsion of the contents of your stomach through the mouth or nose. Typically preceding vomiting you will feel nauseous, sweaty, and/or experience abnormal amounts of saliva.
What causes vomiting?
Vomiting can be caused by gastrointestinal infections or disorders, ulcers, or irritable bowel syndrome (IBS). Motion sickness, stress and poor eating habits can also contribute to vomiting, as well as alcohol consumption or overeating.
A migraine is a common headache which can last from a few minutes up to days at a time and can often go along with flashes of light, nausea, tingling in the arms and legs, blind spots, vomiting, and increased sensitivity to light and sound. 
What causes migraines?
Migraines can be caused by a pre-existing condition or may be genetic in origin. Wine (and aged cheese) can cause a migraine due to the compound tyramine. You may experience a migraine with aura, which are bursts of neuronal activity proceeded by a span of inactivity.
Constipation can be classified as having hardened stool, fewer bowel movements, abdominal pain, or even vomiting. It’s the inability to pass your stool on a regular basis, often going days at a time without relief.
What causes constipation?
When the colon absorbs too much water, it contracts and doesn’t allow stool to pass normally. When this occurs, the stool is slowed down and dries out due to lack of moisture. If it loses too much water, it will become hard to pass and may obstruct the passageway. Dairy products, lack of fiber, and irritable bowel syndrome (IBS) are common causes of constipation.
Isagenix side effects are few and far between, but there have been reports of vomiting, constipation, and migraines, among some others. In order to save yourself from issues, you should always seek the advice of a doctor before taking any kind of weight-loss supplement. Specifically, if you are under the age of 18, pregnant or nursing, taking medications, or have a pre-existing medical condition.
Isagenix is a weight-loss company that offers both meal replacements and supplements. There is no shortage of product reviews and, though most mention nothing about side effects, we did find a few here and there.
“My first day of cleanse I ended up vomiting and dry heaving about 13 times. It was horrible. It made me so sick.” Regina
“I am constantly nauseated. I am weak. I have sharp pains in my stomach all the time.” Diana
“On my first cleanse day I felt even worse. Stomach aches, head aches, and sooo hungry. On day 2 of the cleanse I started getting very sick (diarrhea and horrible stomach cramps.)” Justin
“Ended up vomiting before I got to my last dose of the day, plus I felt like a zombie all day. On the second week I was constipated.” Tonia
“I kid you not, cramping up and down my digestive system and vomit convulsions except there was nothing to vomit up.” Kat
“It made me so sick and my guess is the high milk content. I didn’t even lose a lot of weight…after two weeks I stopped losing and got really bloated and sickly.” Tamara
“I’m only on my second day of the Isagenix 30 day challenge and I started feeling nauseous and I threw up. I still don’t feel too well.” Sarah
“I started Isagenix a couple of years ago. Had a VIOLENT reaction. Throat started burning, mouth burning, one of the worst migraines I had ever had.” Donna
“I started the 30 Day Cleanse a little over a week ago, and I MISERABLE! For the first 5 days, I felt hungry, I had headaches and waves of nausea.” Jess
“The product was awful, she tried it and vomited and it made her shaky and sick.” Ranae
“The supreme shot you take in the AM and the cleanse you do once or twice a week can make you sick, sick sick. Vomiting is an absolute side effect. I thought I was going to need medical attention it got so bad.” Regina
You’re never going to find a supplement that’s 100% free of side effects. What you’re looking for are customer reviews showing they are extremely rare. Leptigen is one like that.
Isagenix offers a meal replacement shake (IsaLean) that supplies 240 calories, 24g of protein, 24g of carbohydrates (11g of sugar), 6g of fat and 8g of fiber. The milk-based shake is packed with a large percentage of many vitamins and minerals, but there's nothing unique in the formula.
Isagenix Ingredients and Supplement Facts
Serving Per Container: 14
|Amount per Serving||% DV|
|Exclusive Myo-IsaLean Complex||*||*|
|- Whey Protein Concentrate||*||*|
|- Milk Protein Concentrate||*||*|
|- Low-Heat Nonfat Dry Milk||*||*|
|Natural Dutch Cocoa Powder||*||*|
|Sunflower Oil Powder||*||*|
Other Ingredients: Natural flavors, olive oil powder, xanthan gum, flax seed powder, medium-chain triglyceride oil powder, Ionic Alfalfa leaf extract, potassium citrate, magnesium oxide, tricalcium phosphate, sea salt, enzyme blend, magnesium citrate, silicon dioxide, yucca root powder, vitamin C, magnesium stearate, psyllium seed powder, biotin, selenium amino acid chelate, cinnamon powder, stevia leaf extract, vitamins and minerals
We looked into the Isagenix ingredients to give you the details you need. Below are three of the most used.
Whey Protein Concentrate
Whey protein concentrate is derived from the watery portion of milk that is left behind when making cheese. It has many uses. It is often used for athletic performance or supplemental intake for those who are lactose intolerant.
What Is It Supposed To Do?
Whey protein concentrate is a source of protein that may help improve the nutritional content of your diet. It is possible that it can be used for eczema, allergies, psoriasis, and weight gain in those with HIV/AIDS.
In a study published in the Current Opinion in Clinical Nutrition and Metabolic Care, “…whey protein may affect glucose metabolism and muscle protein synthesis.”  However, they do suggest in the conclusion that more studies need to be performed in order to gain a full perspective on the substance.
Rhodiola Root Extract
Rhodiola is a plant. Its roots are used for various medicinal purposes. It is often used for energy, stamina, mental strength, and other physical ailments.
What Is It Supposed To Do?
When certain compounds are extracted from the root, Rhodiola is thought to, according to WebMD, “…help protect cells from damage, regulate heartbeat, and have the potential for improving learning and memory.”
In an assessment performed in Rhodiola published in the European Medicines Agency, “The published clinical trials exhibit considerable deficiencies in their quality. Therefore ‘well-established use’ cannot be accepted.”  However, the assessment did acknowledge the extract’s capability to help reduce stress.
Ionic Alfalfa Leaf Extract
Alfalfa is a plant in which its leaves, sprouts, and seeds are used for medicines. It is said that it may help with various ailments, including kidney, bladder, and prostate conditions.
What Is It Supposed To Do?
Alfalfa is supposed to help lower cholesterol, specifically by stopping or slowing the amount absorbed in the gut.
The University of Michigan’s Health System did some research on Alfalfa and found it may be used for menopause, high cholesterol, and poor digestion. However, there is no word of weight-loss in the information they provided.
We think ingredient research is not just helpful, but necessary. In our research we’ve found a few products from companies that understand that – like Leptigen.
- 1. Effects of whey protein supplements on metabolism: evidence from human intervention studies. (2011). Current Opinion in Clinical Nutrition and Metabolic Care. May 7, 2016.
- 2. Assessment report on Rhodiola rosea L., rhizoma et radix (2011). European Medicines Agency. October 5, 2016.