Updated: 04/18/2017 - Site operated by Leptigen
By Summer Banks Apr 07, 2017

People are talking about Isagenix. So we decided to take a closer look at the ingredients, side effects, and clinical studies. Additionally, we read hundreds of user comments and reviews. Then, we took this information, summarized and compacted, to give you the bottom line.

Isagenix Readers: Click here to find out why we're giving away samples of our product, Leptigen.

What Is Isagenix?

To start, Isagenix is a supplement company offering weight-loss solutions. Products include meal replacement shakes [1], formulas to flush toxins from the body and energy boosters (caffeine). [2] There are supposedly no laxatives used in any cleansing formula, which is a good thing because misuse [3] can cause side effects. [4] Some are taken in the morning and others at night.

The Isagenix products, introduced to the market around 2002, appear to contain natural ingredients, which is always good but it doesn’t necessarily mean they are free for any negative potential. [5] They’re available by phone and from marketing associates. We like the good BBB rating, and the longevity of the company, but read on…

Isagenix Cost – “Over the Top?”

The first concern is the prices associated with Isagenix products. “You can’t put a price tag on weight-loss,” said our Research Editor. “But, there’s a problem when a company charges two or three times that of others.”

“I should have listened to my smarter side before dishing out close to $400 for this product, but I’m only human and fell for the empty promises [which is a problem with multiple companies] [6] that their website offered,” according to one customer.

Another dieter said, “This is an very small jar for the very high price.” This was a complaint from multiple people who chose to buy Isagenix products.

According to several Isagenix reviews, high cost is not expensive to some.

As one buyer says, “Great price/Great product.”

Another stated, “My favorite way to start the day and price is approximately equal to other protein shakes.”

Buyer Reviews – “Not Good”

According to Isagenix reviews, customers complained about the taste, cost, Isagenix side effects and a host of other issues. “All of this stuff tastes nasty. Like a big glass of grape cough syrup,” offers one dieter.

“I didn’t like it. It made me feel nasty. It wasn’t what I expected. Didn’t work for me,” claims a customer.

Just because there are negative comments doesn’t mean that reviews of Isagenix aren’t positive.

“It just becomes a way of life…a healthy way of life,” says one user.

Another offers, “I have had success with weight loss and feeling better with these products.”

In our research, we’ve found a strong connection between poor customer experience or high price, and a negative effect on long-term success. There’s an issue if Isagenix fails the dieter in any way.

The Science – “Evidence to Back the Products?”

Isagenix offers some strong marketing materials, but selling a product is about more than convincing a reader to buy. We look for science, and there’s just nothing on the official website. However, we know from research published in peer-reviewed journals, that meal replacements [7], especially those high in protein and fiber [8] [9], can work to curb appetite by slowing the digestive process. [10] We see the addition of whey, but fiber doesn’t appear to be something the formulas are enriched with. Taking a look at the supplements in the line, you have green tea extract and cayenne. [11] Both have shown promise in terms of facilitating weight loss through increased metabolism.

Also: read our Leptigen Weight-Loss Kit review »

The Bottom Line – Does Isagenix Work?

Has the time come to sprint out for these products? The Isagenix company has longevity on its side and a supportive customer service department, but we have hesitations about recommending the supplements. The company doesn’t bother to share clinical research, though it does exist from testing in a petri dish to animals to humans. Everything is there for ingredients like whey protein and green tea extract. With that being said, just because the support is there doesn’t mean Isagenix products are stronger or better than the competition. That’s one place the business failed to sell us.

If the time has come to shed those extra pounds, we suggest a supplement with a formula packed with clinically tested ingredients, supported by strong customer reviews and backed by a company that goes the extra mile to give all the facts.

Among the best products we’ve seen this year is our product called Leptigen. It’s made of a proprietary blend of four ingredients. All clinically-tested with results often found in studies published in the Journal of Medicine.

Also, we’re so confident that you’ll love our supplement, we’re offering a Special Trial Offer, which a good sign.

Previous Isagenix Review (Updated June 5, 2014):

Isogenix Product Line - What You Should Know

Isagenix is marketed as a company that wants to impact world health, according to the Isagenix website. The company has a line of products for cleansing, nutrition, and skin care. Some product lines include 30 Day Cleanse, Ionix Supreme and Isalean. Similar to the Isagenix line, David Kirsch is a a mind-body wellness guru with a line of drink mixes, supplements, and snack bars that promotes a holistic approach to fitness. One of the products in the Isagenix cleansing line, Cleanse for Life, is advertised on other Isa weight loss reviews as a tool for weight loss along with energy and good health. With their abundance of products you can find variations for different health solutions such as weight loss, snacks, cereals, energy and anti-aging. (Take a look at their wikipedia page if you'd like). Other companies that have similar product lines are Yoli Better Body System, Purium and Naturade. The bottles of Cleanse for Life are sold in a two pack, and each 32 ounce bottle is good for two cleansing days. This product appears to be recommended as a part of a complete system designed to cleanse your body over a 30 day stretch. It is also sold as part of the accelerated nine day program, which promises an average weight loss of seven pounds during that time frame. They also have meal replacement options, including shakes and soups. A similar meal replacement product is Prolessa Duo which is an appetite suppressant. The entire product line is available from the official Isagenix website, and also through a network of independent affiliate retailers similar to the classic Avon business model. We are pleased to see that the company provides complete ingredient lists for all of its products, but we are not so inclined to buy into the idea of a complete system with numerous products as the best weight loss method. It's nice to know Isagenix has a favorable BBB rating. We believe that many dieters can find success through a low calorie diet, daily exercise and a single, effective weight losssupplement. Incorporating an exercise routines like PiYo might help in the weight-loss process.

Ingredients in Isagenix Products

The ingredients in the berry flavored Cleanse for Life include a proprietary blend that contains aloe Vera leaf, IsaLyte trace minerals, Pau d'Arco inner bark, suma root, eleutherococcus senticosus root extract, burdock root, fennel seed, peppermint leaf, licorice root, choline bitartrate, inositol, betain HCL and I-methionine. We go over the Isagenix ingredients in greater detail here. Another similar weight loss product that contains aloe vera is Calorad. By the way, it's interesting to view science produced by Isagenix themselves here. We do not see anything on this list that stands out as an effective weight loss supplement. While many of the ingredients may be quite healthy in other ways, we prefer to see an appetite suppressant like Slim Trim U or fat burners like Man Scorch on the list for maximum weight loss benefits. Well known weight loss substances like chromium, green tea, guarana and hoodia are noticeably absent from this list.

Product Features

Some of the Isogenics products appear to be quite pricey, although a double order of the Isagenix Cleanse for Life sells for a reasonable $43 at the time of this review. We could not find any information about a free trial offer or money back guarantee.

The Advantages of Isogenix

  • The idea of cleansing the body from the inside out does offer a number of health benefits.
  • The company provides complete ingredient lists for its products.

The Disadvantages of Isogenix

  • We could not find a money back guarantee.
  • The product we looked at doesn't contain any proven weight loss ingredients.
  • The product is sold as part of a complete package that includes many products and is quite expensive.


We like the idea of an effective cleansing product as a method of jump starting a diet. However, cleansing programs are rarely the best choice for long term weight loss. Another product that states that it cleanses the body is Diurex Water Pills. This particular product doesn't pack much in the way of proven weight loss ingredients to instill much confidence from us in its ability to help dieters lose extra weight. We encourage dieters to look for more effective formulas from other companies for best results.

Isagenix Questions & Answers:

We dug through hundreds of user comments and Isagenix weight loss reviews, for us to be able to write this helpful FAQ.

What are the side effects of Isagenix?

Isagenix side effects may include nausea and weight gain, according to some dieter experiences.

What is in Isagenix?

Isagenix ingredients including whey protein powder, stevia, psyllium [1], various vitamins and minerals, fruit extracts, green tea and apple cider vinegar.

What is the active ingredient in Isogenics?

The active ingredient in Isagenix is whey protein.

What is the Isagenix Cleanse that lasts 9 days?

Isagenix 9 Day Cleanse is a weight-loss / fat burning program that includes a meal replacement shake, snacks, fat burner and detox.

What is Isagenix 30 Day Cleanse?

The Isagenix 30 Day Cleanse is similar to the 9 day variety. There are a couple additional supplements and, of course, it lasts three times as long.

Does the Isagenix diet plan work?

The core of the Isagenix diet plan is the meal replacement shakes. Clinical studies do show weight-loss is promoted when using these products. [2] But, there are quite a few supplements in the line and while some of the ingredients, like green tea extract, have good support, there’s nothing showing these formulas are better than less expensive alternatives.

How much does a bottle of Isagenix cost?

The Isagenix cost is about $50 a week or $200 a month. The other supplements in the line come at an additional cost.

How do you use Isagenix shakes?

You should us Isagenix shakes up to twice daily. There are many supplements to choose from and each will have different directions. Typically you will take them one or two times a day.

Can I take Isagenics products if I have a health condition?

Any weight-loss supplement or program, including Isagenics, should be approved by your family physician. This is critical if you are pregnant, planning on becoming pregnant, nursing, taking medications of any kind, are under the age of 18 or have any medical conditions.

What positives can you find in Isagenix diet plan reviews?

Users tend to like that the shake is easy to mix and take on the go. Some even liked the taste.

What about negative reviews of Isagenix shakes and supplements?

On the opposite end of the spectrum, some users did not like the taste of Isagenix shakes at all. There are also complaints about high price.

Can I use Isagenix if I am lactose intolerant?

It may not be the best idea to use Isagenix shakes if you are intolerant to lactose, as they contain milk-based ingredients.

Do I have to use a blender with Isagenix weight loss shakes?

No, you do not need to use a blender with Isagenix weight loss shakes, but you will find the end result is smoother with fewer clumps, in some cases.

Who makes Isagenix products?

The makers of Isagenix products is Isagenix Worldwide Headquarters.

How do I contact Isagenix com customer service?

You can call Isagenix com customer service at 1-800-877-8111 or 1-480-889-5777 between the hours of 5 am to 6 pm Monday to Friday or 6 am to 2:30 pm Saturday and Sunday. We also found a contact form and email address on the Isagenix com official website.

Can I contact Isagenix through social media?

Yes, you can contact Isagenix through Facebook and Twitter.

There are good supplements out there that offer some support for weight-loss, but our research is to find products that offer more than that. Formulas like the one used in Leptigen give you more than many others on the market.

Isagenix User Tips:

Isagenix is a supplement company that’s known for weight-loss options. Reviews for the 9-day cleanse and 30-day program are all over the web. Among the comments and experiences are a few user tips here and there.


“This program doesn’t require you to stay an Isagenix user, but it does require you to change your lifestyle.”    Madison


“The shake was palatable, I’d even go so far as to say it’s pretty good, just make sure you blend it with ice.”    Erin


“Remember to continue strong everyday or you will fall through.”    Keyla


“It is a commitment. You have to want to do it for it to work.”    Tiffany


“This isnt a magical diet you need to work after to keep the results. Don’t trick yourself and fall back into old habits. You need to change your lifestyle.”    Stephanie


“If you have medical issues, research the true ingredients, and like anything, consult your physician.”    Justin


“Drink all the water you can (it really helps with the hunger pains).”    Garrett


“The key to the program is counting calories.”    Sergey


“Not a magic wand and you do have to follow the program.”    Dawn


“I suggest if you are an unmotivated person who doesn’t like exercise and is looking for a miracle, then forget it.”    Jaimee


Isagenix Scientific Abstracts:

Whey Protein Concentrate

Studies have indicated that the intake of dairy products is inversely related to a lower risk of cardiovascular diseases and metabolic disorders. Whey protein seemed to trigger the effects due to bioactive compounds such as immunoglobulins, glutamine, lactoferrin, and lactalbumin. Also, it’s a great source of branch chained amino acids. Upon further analysis from multiple reports, whey protein had appeared to contain a blood glucose and insulin suppressing effect partly mediated by incretins. It was concluded that whey proteins could affect muscle protein synthesis and glucose metabolism. The evidence shown in the clinical trials are not reliable enough to make any final recommendations due to a particular dosage and the duration of supplement. [1]

Rhodiola Root Extract

A study published showing the effects of Rhodiola in patients suffering from mild to moderate depression. In the participants involved, overall depression, emotional stability, insomnia, and somatization had improved significantly, while those who took the placebo had shown no signs of improvement. There were no adverse side effects reported in the trials, concluding standardized extract SHR-5 had shown anti-depression potency in individuals with mild to moderate depression when dosed with either 340 mg/day or 680 mg/day over a period of six weeks. [2]


The digestion, metabolism, and absorption of fructose differ from glucose. Unlike glucose, fructose doesn’t trigger insulin secretion nor does it enhance leptin production. Since both leptin and insulin act as important factors in the regulation of body weight and food intake, it’s suggested that dietary fructose may be a contributing factor towards increased energy intake and weight gain. [3]

Milk Protein Concentrate

There are reports of epidemiological evidence revealing intake of dairy products being associated with the decreased prevalence of metabolic related disorders. However, there is evidence from studies showing dairy protein as a dietary function aiding in the prevention of type-2 diabetes. Dairy protein may indirectly increase metabolic health by helping weight-loss and reducing fat mass via enhanced satiety, all while improving skeletal muscle growth and performance through the anabolic effects of BCAAs (branch chain amino acids). These amino acids are shown to enhance lean body mass, skeletal muscle function, and muscle protein synthesis. It was also shown that the composition and processing of dairy protein had a direct impact on the digestion process, concluding that dairy protein in milk may possess ways to maximize benefits for metabolic health. [4]

Isagenix Side Effects:

When you think of natural solutions and weight-loss supplements you need to understand the two aren’t always synonymous with no side effects. There is always a possibility for adverse reactions with any formula, although Isagenix side effects are pretty uncommon, with each individual person comes a different set of tolerances.

Stomach Aches/Pains

Stomach aches or pains are typically swelling or irritation in the stomach or abdomen region. They can range from dull to severe and be caused by a number of factors.

What causes stomach aches?

Causes can be something as simple as eating the wrong food, or a food item that doesn’t agree with your stomach. It can be caused by stress or anxiety, or an outlying condition such as gall stones or pelvic inflammatory disease, though rare. [1]


Vomiting is the forced expulsion of the contents of your stomach through the mouth or nose. Typically preceding vomiting you will feel nauseous, sweaty, and/or experience abnormal amounts of saliva.

What causes vomiting?

Vomiting can be caused by gastrointestinal infections or disorders, ulcers, or irritable bowel syndrome (IBS). Motion sickness, stress and poor eating habits can also contribute to vomiting, as well as alcohol consumption or overeating.


A migraine is a common headache which can last from a few minutes up to days at a time and can often go along with flashes of light, nausea, tingling in the arms and legs, blind spots, vomiting, and increased sensitivity to light and sound. [2]

What causes migraines?

Migraines can be caused by a pre-existing condition or may be genetic in origin. Wine (and aged cheese) can cause a migraine due to the compound tyramine. You may experience a migraine with aura, which are bursts of neuronal activity proceeded by a span of inactivity.


Constipation can be classified as having hardened stool, fewer bowel movements, abdominal pain, or even vomiting. It’s the inability to pass your stool on a regular basis, often going days at a time without relief.

What causes constipation?

When the colon absorbs too much water, it contracts and doesn’t allow stool to pass normally. When this occurs, the stool is slowed down and dries out due to lack of moisture. If it loses too much water, it will become hard to pass and may obstruct the passageway. Dairy products, lack of fiber, and irritable bowel syndrome (IBS) are common causes of constipation.

Isagenix side effects are few and far between, but there have been reports of vomiting, constipation, and migraines, among some others. In order to save yourself from issues, you should always seek the advice of a doctor before taking any kind of weight-loss supplement. Specifically, if you are under the age of 18, pregnant or nursing, taking medications, or have a pre-existing medical condition.



Isagenix is a weight-loss company that offers both meal replacements and supplements. There is no shortage of product reviews and, though most mention nothing about side effects, we did find a few here and there.


“My first day of cleanse I ended up vomiting and dry heaving about 13 times. It was horrible. It made me so sick.”    Regina


“I am constantly nauseated. I am weak. I have sharp pains in my stomach all the time.”    Diana


“On my first cleanse day I felt even worse. Stomach aches, head aches, and sooo hungry. On day 2 of the cleanse I started getting very sick (diarrhea and horrible stomach cramps.)”    Justin


“Ended up vomiting before I got to my last dose of the day, plus I felt like a zombie all day. On the second week I was constipated.”    Tonia


“I kid you not, cramping up and down my digestive system and vomit convulsions except there was nothing to vomit up.”   Kat


“It made me so sick and my guess is the high milk content. I didn’t even lose a lot of weight…after two weeks I stopped losing and got really bloated and sickly.”    Tamara


“I’m only on my second day of the Isagenix 30 day challenge and I started feeling nauseous and I threw up. I still don’t feel too well.”    Sarah


“I started Isagenix a couple of years ago. Had a VIOLENT reaction. Throat started burning, mouth burning, one of the worst migraines I had ever had.”    Donna


“I started the 30 Day Cleanse a little over a week ago, and I MISERABLE! For the first 5 days, I felt hungry, I had headaches and waves of nausea.”   Jess


“The product was awful, she tried it and vomited and it made her shaky and sick.”    Ranae


“The supreme shot you take in the AM and the cleanse you do once or twice a week can make you sick, sick sick. Vomiting is an absolute side effect. I thought I was going to need medical attention it got so bad.”    Regina

You’re never going to find a supplement that’s 100% free of side effects. What you’re looking for are customer reviews showing they are extremely rare. Leptigen is one like that.

Isagenix is a popular weight-loss system. We wanted to look more closely at a part of the program that comes up time and again – Isagenix side effects. We dug deep, looking at ingredients and clinical research. Then, we condensed the info to give you the bottom line.

What You Need to Know

To begin, Isagenix offers a weight-loss system that consists of shakes, supplements and a cleansing formula. The program is designed to be utilized throughout the day, helping the dieter lose more weight. All of the products are portable, a great thing for people on the go.

The product line, released around 2002, looks to avoid synthetic ingredients, an excellent choice. You can buy it through an associate or via the customer service department. We like that some people have experienced weight-loss and the company does have years in the business, but read on…

Racing Heart – “Wow!”

The first problem we found with Isagenix side effects was increased heart rate. “Stimulants are proven to boost metabolism, so you’ll find them in plenty of weight-loss supplements,” offers our Research Editor. “There are some dieters who can’t handle the amount of caffeine, and other ingredients, in a formula and that’s when Isagenix side effects happen.”

“The accelerator made my heart race, sweat profusely, and very shaky,” says a user who felt some changes.

Another dieter reports the same, “My heart raced like I was dying and I was so jittery I almost went to the hospital.”

Stomach Issues – “Ewwww!”

We also found mention of another Isagenix side effect – stomach discomfort. “Even though I followed the program to the letter, by the end of the week I was very bloated and had put on 2kgs,” explains a user experiencing problems.

”By noon, I’d been physically ill once. By 6p, I couldn’t stop vomiting and when there was nothing left in my system – I dry heaved until 2am,” says another.

Our research shows a direct connection between small issues, like racing heart rate, and a reduced chance of long-term success. If Isagenix side effects are troublesome, the dieter may turn and run.

The Science

The Isagenix website claims the program is “science-based.” We’re not exactly sure what that means because there’s no more information on clinical support. We know research studies have shown a reduced-calorie diet can promote weight-loss, but that doesn’t mean Isagenix is better than other similar products.

The Bottom Line

The potential for Isagenix side effects interested us and we soon came to a solid conclusion. We like that the company has been around for more than a decade and there are some dieters who’ve lost weight, but we can’t recommend a system that causes negative reactions like racing heart rate and stomach discomfort. We’re also concerned that no clinical research is there to prove this program is better than more affordable ones.

If you’re ready to take a weight-loss journey, we suggest going with a supplement that offers clinically proven ingredients that don’t cause side effects.

Of the products we’ve reviewed in 2016, one of the best is Leptigen. The formula is made up of four ingredients, packaged in a proprietary blend that has been clinically tested and shown to promote metabolism and fat loss. No adverse side effects have been reported and dieters are talking about seeing some pretty amazing results.

Plus, the makers of Leptigen are confident enough in the formula to offer a special trial offer, a good sign.

Isagenix offers a meal replacement shake (IsaLean) that supplies 240 calories, 24g of protein, 24g of carbohydrates (11g of sugar), 6g of fat and 8g of fiber. The milk-based shake is packed with a large percentage of many vitamins and minerals, but there's nothing unique in the formula.

Isagenix Ingredients and Supplement Facts

Serving Size: 2 Scoops
Serving Per Container: 14
Amount per Serving % DV
Exclusive Myo-IsaLean Complex * *
- Whey Protein Concentrate * *
- Milk Protein Concentrate * *
- Low-Heat Nonfat Dry Milk * *
Fructose * *
Natural Dutch Cocoa Powder * *
Isomaltooligosaccharide Powder * *
Sunflower Oil Powder * *

Other Ingredients: Natural flavors, olive oil powder, xanthan gum, flax seed powder, medium-chain triglyceride oil powder, Ionic Alfalfa leaf extract, potassium citrate, magnesium oxide, tricalcium phosphate, sea salt, enzyme blend, magnesium citrate, silicon dioxide, yucca root powder, vitamin C, magnesium stearate, psyllium seed powder, biotin, selenium amino acid chelate, cinnamon powder, stevia leaf extract, vitamins and minerals

We looked into the Isagenix ingredients to give you the details you need. Below are three of the most used.

Whey Protein Concentrate

Whey protein concentrate is derived from the watery portion of milk that is left behind when making cheese. It has many uses. It is often used for athletic performance or supplemental intake for those who are lactose intolerant.

What Is It Supposed To Do?

Whey protein concentrate is a source of protein that may help improve the nutritional content of your diet. It is possible that it can be used for eczema, allergies, psoriasis, and weight gain in those with HIV/AIDS.

Clinical Research

In a study published in the Current Opinion in Clinical Nutrition and Metabolic Care, “…whey protein may affect glucose metabolism and muscle protein synthesis.” [1] However, they do suggest in the conclusion that more studies need to be performed in order to gain a full perspective on the substance.

Rhodiola Root Extract

Rhodiola is a plant. Its roots are used for various medicinal purposes. It is often used for energy, stamina, mental strength, and other physical ailments.

What Is It Supposed To Do?

When certain compounds are extracted from the root, Rhodiola is thought to, according to WebMD, “…help protect cells from damage, regulate heartbeat, and have the potential for improving learning and memory.”

Clinical Research

In an assessment performed in Rhodiola published in the European Medicines Agency, “The published clinical trials exhibit considerable deficiencies in their quality. Therefore ‘well-established use’ cannot be accepted.” [2] However, the assessment did acknowledge the extract’s capability to help reduce stress.

Ionic Alfalfa Leaf Extract

Alfalfa is a plant in which its leaves, sprouts, and seeds are used for medicines. It is said that it may help with various ailments, including kidney, bladder, and prostate conditions.

What Is It Supposed To Do?

Alfalfa is supposed to help lower cholesterol, specifically by stopping or slowing the amount absorbed in the gut.

Clinical Research

The University of Michigan’s Health System did some research on Alfalfa and found it may be used for menopause, high cholesterol, and poor digestion. However, there is no word of weight-loss in the information they provided.

We think ingredient research is not just helpful, but necessary. In our research we’ve found a few products from companies that understand that – like Leptigen.

Isagenix is one of those programs that market strong to dieters, so we wanted to learn more about Isagenix ingredients. We took side effects, clinical research and customer comments into consideration. Then, we refined and summarized to give you the bottom line.

What You Need to Know

First off, Isagenix ingredients are divided between shakes, cleanses and weight-loss supplements. Some include whey protein, magnesium, aloe vera and burdock. Complete lists are available on the official website. The products are designed to be used together to help dieters lose more weight. You can take it on the go, so you don’t have to worry about missing a meal.

The product, offered up by Isagenix International LLC, doesn’t look like it uses any synthetic ingredients, always a good choice. You can buy from distributors only. The official website doesn’t offer sales or prices. We like that ingredients are listed online and there are some positive reviews, but read on…

Isagenix Side Effects – What to Watch Out For

The first problem we saw with Isagenix weight-loss was hunger. “You can skip meals and reduce calorie intake and feel hungry all the time without this program,” explains our Research Editor. “The difference between a good diet and one that’s bound to fail is control of that feeling.”

“What this cleanse does is starve you for thirty days, encouraging you to consume somewhere in the vicinity of 1,000 kcals on shake days and essentially zero kcals on cleanse days,” says one follower.

Another claims, “I only used the Isagenix for 1 week and thought I was going to starve to death.”

High Cost of Weight-Loss

If you want to spend tons of money on Isagenix products, you can feel free to visit a distributor website. “My friend who is an isagenix associate says…it is VERY VErY expensive to maintain,” says someone who knows a distributor.

Another user claims, “I started this 30 day cleanse program, very very expensive and i havent seen any results.”

It takes something small, according to our research, to knock down your chances of long-term success. If the Isagenix diet is too expensive, it may be difficult for dieters to follow over time.

The Science

You’ll spend more than $350 on a weight-loss kit from Isagenix. There’s no clinical research proving this huge price is substantiated. You can purchase meal-replacement shakes and a proven supplement for a fraction of the cost and see results. At DietSpotlight, it’s science that gives us the information we need to give a thumb up or thumb down. In the case of Isagenix ingredients, if they are far too expensive, dieters may need to look for something that’s both affordable and scientifically proven.

The Bottom Line

When we looked deep into Isagenix ingredients we expected to find exactly what we found. We like that the program includes shakes and supplements, but we can’t recommend any weight-loss plan that expects dieters to pay a huge sum of money for something that shouldn’t cost that much. Plus, we’re concerned about side effects associated with some of the pills.

If you’re ready to take that weight-loss journey, we suggest going with a supplement that packs clinically proven ingredients into an affordable package.

Among the finest supplements we’ve encountered in 2016 is Leptigen. With four ingredients in a proprietary blend backed by with published scientific research showing it helps improve metabolism and fat loss, we’re impressed. There are no reports or mentions of negative side effects. We did find numerous reviews claiming some amazing results.

Plus, the product is offered by a company so confident in Leptigen that they’re offering a Special Trial Offer, nice addition.

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Dietspotlight Author
About the Author:

Summer Banks, a content strategist at Leptigen, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 3.6. From 643 votes.
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User Comments (514)


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I wonder if all these positive cmments on here telling people to stick with the Isagenix programme are actually isagenix distributors within the MLM culture and this is another social media way to counteract the “real” issues people are having with this product – remember the company cant provide much in the way of clinical information and finally , of course you can lean up and lose weight if people stop eating junk food and processed food high in sugar – you dont REALLY need Isagenix products which cost a lot when you start eating healthy using only whole foods and HAVING AN EXERCISE REGIME – WE AS HUMANS SPEND SO much money of things that we really dont need. Isagenix is a multi level marketing business with an average product –


I wish that were the case Ricardo. As a dietitian it’s not possibly to get All the nutrients your body needs without supplementation. Our food supply is so full of hormones, pesticides, not to mention food is made in mass and picked out of season or destroyed though processing with heat. I haven’t meet anyone that gets in the recommended fruits/vegetables and protein from higher grade than USDA to support the body’s function without spending 3 times as much as Isagenix. A healthy juice these days cost $8-10 and that just for a few servings. It’s extremely expensive, and time consuming. I’m the end most clients I had still didn’t get the results and were left frustrated. We have to cleanse our bodies, if we don’t it’s like keeping the same oil in your car for the life of the car, not good. Just some things to considersmile

Kristy Lee

I tried ISAGENIX and have all of the shakes still sitting right there in my kitchen. I haven’t even opened the other cleanse bottle. And I have ALREADY been to the e.r for gastritis and a UTI.. there is not one thing in my regimen that would have caused this except for the ISAGENIX. After hours of research the shake mix is loaded with garbage ingredients and not at all good for you and 8$ juice. . heck ISAGENIX cost me 350$$. With the right frame of mind. Egg whites for protein. Vitamin. C. B. Good ole classic. Túna fish. Chicken breast. Kale,. blueberries & other HEALTHY meals you can lose weight with plenty of rest and water. I lost 63 once . And was diagnosed with hashimotos and thought that this was a quick fix. Quite frankly .. that’s all these things are. God bless. And thanks for your time


Your story is like many I have read, being skeptical is good, having an open mind is vital for not missing out on something that can benefit one. There are clinical studies that include MRI reports that show visceral fat decreases with the Isagenix system vs. the heart healthy diet (both groups exercised the same). This visceral fat is dangerous to health of our vital organs. It does not go away without cleansing on a cellular level. If you would like more information I can send you the links to the studies (published in medial journals).
I appreciate reading all the comments.


I started using the Isagenix Program end June 2016 and have lost 28 lbs. I have a full time job and the program is extremely convenient for me, I save money on purchasing lunch everyday and I’m fully satisfied. The vitamins and Cleanse for Life taken daily has made a huge difference on the way I feel, if I miss a day I definitely feel the affects. I have absolutely nothing negative to say about this program.


I am a product user of Isagenix for over a year. I was super careful to buy into the whole thing when I started. After my headaches were gone and I didn’t have any brainfog I started to really wonder if the hype was true. I lost 34 pounds the first two months and got down to a snug size 8. (started at a 14) . I was blown away. I still use two shakes a day because I love the way I stay full, they taste amazing after day 4, and every time I don’t take the system I start feeling crappy again. The results stand where they are – I don’t care what business model it it… I cant get this at GNC, I cant get this at Walmart and I will pay $300 every month to have my life back. Its not for everyone but it changed everything for me. Plus my support system I get from my friend who got me set up on the products is nothing I would ever get from buying it from a store. I cant say enough about my experience.

Lady Blue

My family uses Isagenix. I am not a salesperson, just a user. But we get a discount by paying a membership of $20 a year. We love it because it’s convenient and I love the taste of the chocolate shakes! As for the price, I have compared it to other organic meal replacements and it is the same price per container. When comparing products we have to make sure the others are free from GMOs and are all natural. Plus they should be “meal replacements”, not just whey protein. That’s what costs more. The whey protein Isagenix uses to build muscle is sourced from cows in New Zealand that are only milked in their natural season, not 12 months a year. They aren’t given growth hormones and grain that is not good for their digestive system like cows in the USA. I am lactose intolerant and can’t even tolerate organic dairy. But I can use their whey protein with no issues. Good luck, I hope you love it too!


I’ve been using isagenix for 5 months. Firstly, I’d like to clarify I am a distributor but just weighing in as to why I love it.
Before I started I was eating a healthy and varied diet. I was trying to train 3-4 times a week but with my split shifts at the gym I just didn’t have the energy to do it. I started these products because I was fed up and I can tell you I was reluctant to try. I just knew plenty of people getting results and had to test it for myself.
I’m so glad I did. About 3 days in I woke up clear headed and my energy levels were consistent so I didn’t need a nap trough the middle of my day. My clients noticed the changes in me and loved how I carried myself. I dropped a significant amount of weight and have maintained it too.
I would recommend it to anyone wanting to feel the changes I went through.


I started using Isagenix several years ago when it was first introduced on the market. I lost a lot of weight at that time, and I have been using it ever since whenever my weight starts to creep up. I think it tastes great compared to other powdered meal replacements. They have kept the original flavor, which I appreciate, because their chocolate is really the only powder on the market that I can stomach. I love that I can take it to work, or wherever, and have it freshly mixed in a shaker bottle in seconds. There is no excuse for me to reach for something unhealthy to eat when the preparation of this meal replacement is so fast and easy. I still need to munch on snacks throughout the day to get my chewing in, but because of the nutrients supplied by the Isagenix shake, I reach for healthy snacks with no cravings. I usually eat some apple slices or raw almonds, a piece of string cheese, etc. this helps be get through the day between shakes. It usually takes me 3-5 days of taking shakes to get into the habit of it, but after that I can stick to shakes and snacks for a week or two at a time depending on how much weight I need to take off. The shakes are pricey, but compared to purchasing the groceries that would supply the same nutrients, it is a real deal. Like ANY diet, you have to stick with it. It will seem expensive if you aren’t using the product and seeing results. I used to sell Isagenix, and so many of my friends and work colleagues had such great success with the program, I know it is a winner.


I’m thinking about starting isagenix, but really don’t want to use it forever. I am concerned that if I use it until I reach my goals and then quit, I will gain all the weight back. Is there a way to maintain after quitting isagenix? Or do you think it’s something you shouldn’t quit?

Samantha Thorne

Once you start on isagenix you wont want to quit. it will become part of your daily routine. Please message me if you are interested in moving forward in this direction. I lost 36kg with Isa and that was 6 years ago and I am still using it daily smile

Garry Ryan

I’m an athlete and Even though isagenix is pricey I always go back to it to get my body weigjt down leading up to a major competition. I try throughout the year to try other stuff and spend way more in the long run to get my bodyweight down like isagenix does but i fail .
The first time I tried this product I was amazed . I was training 5 to 6 days a week weight would escalate between 91 and 93 kilo . Within a week of using it I dropped down to 87 increased my speed and stride length plus prolonged my lactic acid which meant i could sprint over a longer distance holding form.


So far it’s fantastic. I used to be a competitive powerlifter, then I got injured and got fat. My biggest concern with any weight lost problem is losing muscle mass and strength. After a week of Isagenix I lost 8 lbs and was actually stronger in the gym on my bench press and incline bench. This program works for me because I am a foodee – I love to eat to my detriment. The shakes fill me up and prevent me from feeling weak. Much easier than doing Adkins – I only lasted a few days. I recommend this program for jocks who have gotten fat.


I’ve been using it now for 3 months and have gotten great results. and I havent even been exercising to get them. Must hold strict to it and no cheating or sneaking meals/food in between. Lost inches all over in the first 6 weeks as well as 9lbs so I know it was fat burn more so than losing muscle mass. have gotten some muscle definition back in my biceps where I’ve lost 1.25 inches on my left arm and 1″inch on my right. my butt is going flat now so have started back at the gym to build muscle back up to keep my shape. A friend whose an athlete got me on the program when I saw great results on her. she worked out strenuously as well as doing the isagenix shakes twice a day with one meal and snacks only. she leaned out so much she could have enetered a body building competition. I didnt want to go that far but I like fitting my clothes better. dropped from size 10 to a curvy six. I don’t want to lose anymore now so am in maintenance mode. How much would you pay for sexy? I saved money because I didnt have to buy food!!! people forget that. so to me it is worth it. add up what you spend on restaurants, groceries and alcohol for a month. then put it towards a program like this.

Monica Marshall

I’ve been on Isagenix for 2-3 weeks. I agree the Shakes don’t taste all that great, but for me my Ive had a lifetime of great tasting food. I just turned 50 & have Hashimotos Thyroiditis. I take Synthroid for my thyroid & have felt miserable for years. I have not been able to lose the 30-40 lbs. for lack of energy. Since I’ve been on Isagenix I feel like I have more energy & am doing things I have not in years (playing tennis,bike rides). I am grateful for the extra energy and am not wasting it. Thank you Isagenix, Life is Good again!


When do you take your Synthroid pill. Since they recommend not taking iron,calcium or multivitamin within 4 hours of taking the pill I wondering where to put it in the schedule of all the 30 day program stuff.

Hi Sue! For detailed product and usage instructions, please refer to the Isagenix official website for more information.


Awesome. Do,you have a good support team. I do and it made all the difference in the world. They are at my disposal and any time I find I don’t like the tast of something they give me great ideas on how to change stuff a bit. That’s another thing I really like about Isagenix, it’s not a plan that dictates specifically what you have to do. You adjust the program to fit your specific needs. It great.


I have been on Isagenix for three years and have had amazing results! More energy, greater performance in my workouts, and released 18 pounds! I will be using isagenix products forever! I am now healthier and happier than ever! My daughter lost 75 pounds! She looks and feels amazing! All I can say the program worked for us!


i am a 50 year old male 5’9″. Back in September, 2015, I weighed 192 lbs.After my physical the doctor told me I had to lose weight. I did not feel good about myself. In February of 2016 I started isogenix. I did the 9 day. I went down to 179 lbs. I followed the program religiously. I am presently on another 9 day run and stand at 172 lbs. my goal was 170. For me this has been a great way to lose weight. It has made me lose all the weight and bring my body to a healthy weight. I would highly recommend it to anyone. It gives you a means to lose weight. The trick is to follow the program religiously. That’s the hardest part. But it’s mind over matter. What’s more important, the end result or satisfying your craving? I have also educated myself on eating the right foods. Staying off carbs and sugars. It’s usually what you eat 90% of the time that matters.


I have been using Isagenix since January. It has changed my life and my husband’s life. We have helped numerous friends and family change their lives as well. I don’t get the impression that the person that wrote the above information on Isagenix has actually used the program, as there are many inaccuracies. When we give our bodies the nutrition that it needs, our bodies function the way that they are designed to, which is exactly what Isagenix does.


Hi. I am about to purchase Isagenix does it really work. i am skeptical on using it does it really work. I was looking to see if there are any effects on it. Let me know more thank you.



Amanda, I’ve been using the Isagenix products for almost two years now and I will NEVER go back. You can’t get the nutrition from our food these days that we used to get from the same food in the 50’s and 60’s. With my Isagenix, I KNOW I get all of the nutrients I need in my body every single day. Plus I cleanse twice a month to clean out the toxins. In my first 3 weeks, I had lost 4 inches around my waist and went from a 31 inch waist to a 27 and now I’m a 26. I’m 51 years old and I have more energy and I look and feel younger than I did when I was in my 30’s. If you follow the system, IT WORKS. The only way it can fail you is if you don’t follow it exactly. I hope this helps you. They also offer a FULL 30 day money back guarantee no questions asked, if you’re not happy. <3 <3 <3


I’m 60, feel like 30, I’ve been using Isagenix products since February of 2016. I lost 35 pounds, gained tons of energy, got off the couch and feel amazing. The first 30 days was a challenge for me but I made up my mind it was time for a better, healthier, more active lifestyle. Isagenix provided that for me. I had tried many different programs in the past that didn’t produce any results. One for over a year because my daughters were selling it. No results with that one. I did intentionally change my exercise regime. I just felt more like being more active. You need to get involved with a good support team that will teach you how to make it work and be pleasurable for you. I did and it’s amazing. Convince yourself that your are truly ready to commit to a healthier lifestyle and give it a full dedicated 30 days. Then answer your own question. That’s what I did and I’ll never be without my Isagenix for the rest of my life.

Hi Amanda, Isagenix is a supplement that offers weight-loss solutions that some users claim aid in weight loss. For details on the product please visit the Isagenix official website.


I tried the 9 day cleanse last month and lost 9 pounds. I am doing it again this month and have lost 3 lbs in my first 3 days. The products work fine for me and I love the flavors of the shakes. The cleanse powder does take some getting use to. So far my experience has been positive. I plan on continuing the product until I reach my weight loss goal.


Can’t guarantee that what you buy on eBay is the real deal. Buying from eBay does not get one a 30-day money back guarantee. Buying individual products that are designed to be used together with synergistic effects will most-likely not produce the results one is looking for when starting a system like this.

For eBay purchases I stick to collectibles. Not food.


I travel (fly) weekly for work, while I’m on the road it always seemed I had no energy and I gained a ton of weight. First step was getting my self back to the gym, I then quickly hit a wall. It was my diet. I’ve signed up for isagenix and in the first month I lost 8 pounds, and it seems I’ve put a decent amount of muscle on. Overall the best thing I like is how great I feel, love all the energy I always have. I already spent money at places like GNC etc…. so this is a easier solution, plus the support the company gives is amazing! Absolutely love it!!


Hello everyone
I liked isagenix begin with. I followed the program, drank lots of water, lost weight but spent lots of money. Thats just my experience.


Did you have a good sponsor and support team to help you maximize the program?


Isagenix simply does not work. I tried it once and lost 9 lbs. Continued to use the product but lost no more weight. About 6 months later thought i would give it another try. Lost 5 lbs. And gained 3 back while STILL ON PROGRAM! Save your money. Eat well and exercise. Its the only way!


It’s about lifestyle change. Not just try something once in a while to lose a few pounds. I’ve stayed consistent with Isagenix since February of 2016. I’ve lost 35 pounds, changed my eating habits and feel awesome. I’m committed to lifestyle change not just a quick weight loss gig. It really works if you actually stick to it.

Your Name

There aren’t any stimulants in Isagenix products, including the snacks. There is a small amount of naturally occurring caffeine in the chocolates. The fructose used to sweeten the shakes comes from low-glycemic beet sugars. It is about the equivalent of what you would find in one small orange.

Your Name

Isagenix is food, not medicine. Associates are not physicians and cannot be expected to give medical advice. Last, it is doubtful that you “suddenly” developed gallstones and no way to prove that they were caused by the whey protein. Many things, including diet, can lead to the development of gallstones, but w/o an ultrasound proving that you didn’t have gallstones prior to starting Isagenix, there is no evidence that it was the cause. I hope you have recovered. The shakes are not a meal “supplement,” they are a complete meal replacement providing appropriate amounts of fat, protein, carbs, fiber, trace minerals, etc. Good luck in your search for “cleaner” food.

Nurse 4 Lyfe

Weight loss can be achieved through a myriad of interventions and Isogenix is only one of them. I recently attended a showing of this product but was “put off” by the lack of knowledge (about the product) from the representative, pushy sales pitch, limited research, and insistence that exercise is not essential for long-term weight loss. Really? The rep insisted that all one needs for successful weight loss is to drink the shake twice daily and eat whatever you want for the third meal! There is no Magic Bullet. I chose to exercise common sense. I will continue nutrition/weight management the “old-fashioned” way by exercising, decreasing carbs and eating a low glycemic diet of fresh fruits/veggies.

Hi Nurse 4 Lyfe! While there’s no magic bullet, there are options available to help boost metabolism, fat loss, which could jump start weight-loss; without costing an arm and a leg. You may want to consider clicking above for the Leptigen sample.