In my never-ending quest for that perfect diet product, this week I did some serious research and wrote this Plexus Slim review. Touted by one news station as the “Pink Drink Diet Craze,” we needed to know more about what’s behind the curtain. So, we looked closely at ingredients, side effects, and clinical evidence. Plus, we read hundreds of user comments from around the web. Then, we condensed that information to offer you the bottom line.
What is Plexus Slim?
First off, Plexus Slim is a dissolvable powder that’s mixed with water. The product is made up of:
- chromium polynicotinate
- green coffee bean 
- garcinia cambogia
- alpha lipoic acid 
- mulberry fruit extract
You can drink it twice daily to help you lose weight, according to the official website. It can be taken on the go, a plus for busy dieters.
Plexus Slim was introduced in 2011 – that’s about five years in the business. The official website carries the product, but we don’t think it is available in stores. Plexus Worldwide, the makers of Plexus Slim, has a good BBB rating and there are some good ingredients, but there are a couple of concerns…
Price – “Are You Spending Too Much?”
The first thing we took into consideration was Plexus Slim’s price. “This product has a couple of ingredients that can help you lose weight  ,” says the Research Editor. “The problem is you have to buy one to two bags to last one month, and that means you could spend more than $170 and many people just don’t have that much to spend.”
“This stuff is expensive. I can’t believe you didn’t comment on the price of this product. It’s $80 [two weeks if you drink two shakes a day] for a one month supply of the slim drink and another $30 a month if you want the accelerator,” was one response to Plexus Slim cost.
Another agreed, “I have considered Plexus but it is too pricey for me. I would love options that are a fraction of the cost.”
It’s important to note that not all buyers felt it was too expensive.
One customer said, “As far as costs go, compared to others out there, Plexus is really affordable!”
Plus, the company gives you the opportunity to spend less.
“I also am a proud ambassador for Plexus, I joined to save money,” a seller shared.
Is There Enough Research Behind Plexus Slim?
We are a bit concerned by the limited clinical research into Plexus Slim. There’s been mention by a representative of the company that “drugs need to have clinical trials.” This clearly doesn’t address supplements, but we did find scientific support for a couple of the ingredients.
“When you take [a product] that has not been clinically tested, in addition to not knowing where the product is manufactured, there is a good chance you are going to feel [bad],” said a user.
Despite the fact that it has not been clinically tested, there is some positive support.
As one user put it, “I’ve been on Plexus for about a month – no weight loss for me (some inches maybe) but I do feel better.”
“I have been using Plexus Slim for little almost 2 months, I take the drink and Accelerator and my energy level is up and my hunger is down,” was another experience.
In our experience researching weight-loss supplements, we found a small negative, like high cost or lack of support (Plexus doesn’t offer representatives), can hinder your chances of long-term success. As such, Plexus Slim’s price and lack of customer service may be potential problems.
The Science – “Any Evidence?”
Though a Plexus Worldwide representative alluded to the idea that supplements don’t need to be tested, the ingredients in Plexus Slim have been.
- Garcinia cambogia testing falls on both sides of the fence. According to the Journal of the American Medical Association, “Garcinia cambogia failed to produce significant weight loss and fat mass loss beyond that observed with placebo.” 
- Green coffee bean, on the other hand, does show some support for weight-loss. But, we have to take into account the quality of the findings. The journal Gastroenterology Research and Practice says, “It is concluded that the results from these trials are promising, but the studies are all of poor methodological quality.”  The final ingredient, alpha lipoic acid, has been shown to help with weight-loss when taken as 1800mg daily. There is far less than that amount in Plexus Slim.
- Alpha lipoic acid, has been shown to help with weight-loss when taken as 1800mg daily. There is far less than that amount in Plexus Slim.
The Bottom Line – Does Plexus Slim Work?
So, does this one live up to our expectations? We were initially intrigued by Plexus Slim; it is the famous “Pink Drink.” There are a few good ingredients in the formula, and we did find some positive comments. However, what concerns us and leaves us up in the air are:
- Research tends to fall on both sides of the fence – for and against.
- It is a multi-level marketing company, so you may have to find a distributor to buy a reasonable quantity of it.
If you’d like to get rid of those extra pounds, we always suggest a product that combines scientific support, a good price, and a dedicated customer service team.
Among the best supplements we’ve seen this year is one called Dietspotlight Burn. It’s formulated with a proprietary blend of four clinically-tested ingredients. Based on research, it’s been shown these can help spark metabolism, decrease hunger and boost fat loss. User testimonials around the web are amazing.
Dietspotlight Burn is formulated with your success in mind and the company is so confident in it they’re offering a Special Trial Offer.
Plexus Slim, the pink drink, is a 10-calorie diet powder that's supposed to help your body maintain healthy glucose and cholesterol levels. It's also supposed to give you power over food, so no more binge-eating. All ingredients are listed as a proprietary blend, so amounts are not available.
Plexus Slim Ingredients and Supplement Facts
Serving Per Container: 30
|Amount per Serving||% DV|
|Plexus Slim Blend:||531mg||*|
|- Green Coffee Bean Extract|
|- Garcinia Cambogia Fruit Extract|
|- Alpha Lipoic Acid||*|
|- Mulberry Fruit Extract|
Other Ingredients: Polydextrose, citric acid, natural flavors, beet extract (for color), stevia leaf (Stevia rebaudiana) extract, luogan-guo fruit extract, guar gum, silicon dioxide
We dug deep into the Plexus ingredients to give you the details you need.
Green Coffee Bean
Before coffee beans are roasted, they are green. Thus, the name green coffee bean. This ingredient has always been around, but it was Dr. Oz in 2012 that forced it into the spotlight. The doctor said, “this miracle pill can burn fat fast, for anyone who wants to lose weight.”
What is it Supposed to Do?
At the heart of the matter is chlorogenic acid. It is a phytochemical that is supposed to reduce blood sugar levels. This is not the same as helping maintain a healthy level, which can suppress appetite. There is a connection between the acid and the laxative effect of prunes.
The Federal Trade Commission had a different take on things. According to a settlement in 2015, a company “deceptively touted the supposed weight-loss benefits of green coffee bean extract through a campaign that included appearances on The Dr. Oz Show, The View, and other television programs.”
Strong clinical evidence into the effects of green coffee bean extract on weight-loss is lacking, though there have been a few articles with positive results. A study in Gastroenterology Research and Practice reported, “The size of the effect is small, and the clinical relevance of this effect is uncertain.”  There is a long list of medical conditions that are not compatible with this supplement. We strongly suggest speaking with your doctor before taking it. Side effects may include stomach issues, headache or jitters (mostly associated with the caffeine.)
Also known as the Malabar tamarind, garcinia cambogia is a fruit. According to the National Institutes of Health, “[There is] insufficient research to draw firm conclusions. Little to no effect on body weight.”
What is it Supposed to Do?
The hydroxycitric acid in garcinia cambogia is the main component. It’s supposed to stop hunger and help control blood sugar and cholesterol. This effect on glucose levels could help stop cravings. Unfortunately, there’s no science out there that connects this ingredient with weight-loss.
If you take a look at a study published in Critical Reviews in Food Science and Nutrition, “There is still little evidence to support the potential effectiveness and long-term benefits of G. cambogia extracts.”  It is considered safe for up to 12 weeks.
Alpha Lipoic Acid
We have antioxidants in every cell in our body. Alpha lipoic acid is one. The body makes this one, so we don’t see the need to supplement with more, in most cases. There may be a small connection with weight-loss.
What is it Supposed to Do?
According to the University of Maryland Medical Center, “Several studies suggest alpha-lipoic acid helps lower blood sugar levels.” This may be beneficial for people with diabetes, though you should always check with your doctor before starting any new supplement if you have this condition. This is not the same as maintaining a healthy level of blood glucose, which can stop cravings and help you eat fewer calories.
There is some evidence that taking 1,800 mg of alpha lipoic acid can promote weight-loss. But, take into consideration the warnings and possible interactions that come with supplementation. If you are taking medications for diabetes, cancer or underactive thyroid, it is important to speak with your physician beforehand.
We’ve been keeping an eye on a product that offers four clinically tested ingredients; Dietspotlight Burn.
- 1. The Use of Green Coffee Extract as a Weight Loss Supplement (2011). Gastroenterology Research and Practice. September 27, 2016.
- 2. Evaluation of the Safety and Efficacy of Hydroxycitric Acid or Garcinia cambogia Extracts in Humans (2011). Critical Reviews in Food Science and Nutrition. October 6, 2016.
Plexus Slim Side Effects:
In today’s society, weight-loss supplements can play a role in the way we live our lives. However, natural alternatives and safety are not always one in the same. There is a potential for a negative reaction with any supplement, and while Plexus Slim side effects are not common, some individuals may have a different experience than others.
Fatigue can be categorized as being tired or inability to focus. It is not the same as exhaustion, which will last longer, and is not relieved by simply resting. It’s a constant feeling of weariness. It often develops gradually and impacts energy, motivation, and concentration.
What causes fatigue?
There are numerous possible causes of fatigue which include poor blood supply to the body’s tissues, inflammatory diseases or infections which cause sleep disturbances, certain medications, lack of sleep, or physical activities. 
Nausea is an unpleasant feeling you get typically before vomiting. It can be psychological or physical in origin and may also be caused by diseases of organs outside of the gastrointestinal system, making the cause sometimes difficult to pinpoint.
What causes nausea?
Some things can cause nausea, including types of food you eat, ulcers, inflammation of the stomach lining (gastritis), or stress. Along with nausea, you may experience pain in your abdomen as well as sweating or headaches. Nausea itself isn’t a disease but can be associated with several, more alarming causes. 
Headaches are a common ailment that affects everyone at some point. Headaches are pain that occurs in any region of the head and can range from minor to severe and host a variety of levels from dull to sharp to throbbing.
What causes headaches?
A headache could be caused by unhealthy or irregular eating habits, stress, or physical exertion. A primary headache is a nerve, blood vessel, or muscle pain associated directly with your head, while a secondary headache is caused by an external symptom outside of the brain area.
Dizziness can be described as a couple of different things. Lightheadedness is a feeling that can be described as feeling weak or unsteady. Another form of dizziness is vertigo, which differs from lightheadedness, as it causes an unpleasant spinning sensation when stationary.
What causes dizziness?
Dizziness is typically caused by motion sickness, inner ear disturbance, or certain medications, but can also be triggered by poor circulation or infection. Although underlying health conditions may be the cause, symptoms may be brought on by stress or lack of sleep.
Plexus Slim side effects don’t always happen, but there have been reports of headaches, nausea, and dizziness along with some others. It’s always a safe practice to consult a physician before taking a supplement to avoid any unexpected issues, especially if you are already taking medications, are under 18, are pregnant or nursing, or have a pre-existing medical condition.
Side effects are not common in people who’ve used Plexus Slim, but some have been reported by customers and dieters. These do not represent the majority, but there is a risk when taking any supplement.
“I have had a low grade headache from day one, I am tired every afternoon around 3pm.” Lisa
“I’ve been sick all day now. It started with nausea, headache and bit dizzy.” Chele
“I am just asking because I am on day 4 and am feeling unbearably nauseous.” Traysie
“I quit taking it a month ago because I felt very tired in the mornings after taking it.” Nay
“About 30-40 minutes after taking it I had a severe pounding headache that seemed to move across my head.” Samantha
“I have diarrhea every day from this stuff and have increased muscle pain.” Robyn
“It was making me retain water my ankles were so swollen that I could hardly get my shoes on.” Jennifer
“I drink more than plenty of water & have only been on for 4 days but I could sleep all day.” Claudia
“I’m constantly battling a full feeling and I’m exhausted.” Eugenia
“Ever since I took it this morning, I have a slight headache and it feels like I’m zoned out (like you’re in the room but can’t focus in on what’s going on around you).” Samantha
We’re all about limiting the risk of side effects when using a weight-loss supplement. We’ve been noticing that Dietspotlight Burn reviews are amazing with very few complaints.
Plexus Slim Questions & Answers:
We looked closely at hundreds of dieter comments and user reviews about Plexus Slim to come up with this helpful FAQ.
What are the side effects of Plexus Slim?
The possible Plexus Slim side effects, based on ingredient details, may include increased urination, diarrhea, loose stool, abdominal pains, rapid heartbeat, headache, and nervousness.
What is in Plexus?
Plexus ingredients are chromium polynicolinate, xylooligosaccharide, green coffee bean extract, garcinia cambogia, alpha lipoic acid and mulberry fruit.
What is the active ingredient in Plexus?
The active Plexus Slim ingredient is xylooligosaccharide.
Does Plexus Slim work and what is the Plexus Slim diet?
The two primary weight-loss ingredients in Plexus Slim are garcinia cambogia and green coffee bean extract. The first is considered a “fad” ingredient because there’s a lot of hype and little to no clinical research on humans , though animal studies do show weight-loss. The second supplies the chlorogenic acid, which has been associated with a slowing down of the release of sugar into the bloodstream . That could help with hunger and cravings. That means chlorogenic acid could help with weight-loss. No science is presented on the official website.
How much are Plexus supplements?
One bottle/bag of Plexus supplements costs $84.95 on the official website.
How do I take Plexus Slim?
Plexus Slim instructions are simple. Mix one packet into a bottle or glass of water, mix and drink no less than 15 minutes before a meal. You can use the supplement twice daily. There are 15 to 30 servings in a package.
Who makes Plexus supplements?
Plexus Worldwide makes Plexus Slim supplements.
What is Plexus Slim Canada?
Plexus Slim Canada is just another division of Plexus Worldwide.
How do I contact Plexus customer service?
Plexus Slim customer service is handled by Plexus Worldwide, the parent company. You can contact a representative by phone at 1-480-998-3490. If you’d rather write, the address is 15649 N. Greenway Hayden Loop, Scottsdale, AZ 85260. You can also visit the official website (www.plexusslim.com.)
Can I contact Plexus Slim through social media?
Can I take Plexus Slim if I have a health condition?
It is important for women who are pregnant or nursing, people taking prescription medications, anyone with a health condition and/or dieters under the age of 18 to consult with a physician before taking a product like Plexus Slim supplements.
Are there any Plexus Slim dangers?
We were unable to find mention of Plexus Slim dangers in our research.
What do users like about Plexus weight loss?
Some customers like that Plexus Slim weight loss is easy to use, it’s vegan, gluten-free and low in calories, which can help with weight-loss
What do users NOT like about Plexus products?
Some users do NOT like that Plexus products are not backed by real science. There have been reports of negative side effects and customersn’t happy with the huge number of quick weight loss reviews offering no real information.
Can Plexus Slim cause weight gain?
If you do not change your current eating habits and you add Plexus Slim into the equation there is the potential for weight gain.
Are there any free samples on PlexusSlim com?
No, PlexusSlim com does not offer free samples, but we have stumbled on ambassadors or resellers every once in a while that do offer them.
Does Plexus Slim have a money-back guarantee?
Yes, the pink drink offers a 60-day money-back guarantee.
When looking for a weight-loss supplement, it’s best to choose one that’s packed with clinically tested ingredients, from a company that offers amazing support. Dietspotlight Burn is the one we’ve been looking at closely.
- 1. Evaluation of the safety and efficacy of hydroxycitric acid or Garcinia cambogia extracts in humans. (2012). Critical Reviews in Food Science and Nutrition. September 27, 2016.
- 2. Impact of Dietary Polyphenols on Carbohydrate Metabolism (2010). International Journal of Molecular Sciences. October 11, 2016.
Previous Plexus Slim Review (Updated May 9, 2014):
Plexus Slim: What You Should KnowIn order to lose weight you must drink more water, right? Well, the makers of Plexus Slim created a weight loss supplement around that very dieting rule. The small packet flavors water and adds quite a punch of weight loss ingredients. According to the official website, there are no stimulants or caffeine in the formula, so the dieter does not have to worry about jitters and shakes. Plexus Slim's formulation can be found on its official site. Plexus also offers products like Plexus Accelerator which is an appetite suppressant that is formulated with yerba mate, higenamine HCL, hordenine HCL, hawthorn berry, 5-HTP and green tea extract. Another product from the Plexus supplement line is their Plexus Boost which is taken daily to potentially suppress appetite, boost energy levels and speed up weight loss. Another similar product that claims to have similar weight loss results is the meal replacement Glucerna. Caffeine, however, is a proven weight loss ingredient, so if Plexus Slim included caffeine it would be a benefit, not a drawback. Of the ingredients listed on the product label, only one is proven to have any benefit on weight loss.
List of Ingredients in Plexus SlimProprietary Health Blend: Polydextrose, Citric Acid, Natural Flavors, Beet Root, Grape Skin Extract, Stevia Extract and Lo Han Extract. Chlorogenic Acid, Citrin K, Alpha Lipoic Acid, Oxypregnane Steroidal Glycoside and Chromium.
Product FeaturesYou have to love a diet product that makes huge weight loss claims and then offers up an ingredient list that does not support those claims. There are several plant extracts and filler ingredients, but a few stand out. The alpha lipoic acid found in Plexus Slim can also aid in treating diabetes, HIV, cancer, liver diseases, rheumatoid arthritis, Alzheimer’s disease, and other conditions. Chromium is typically used to control blood glucose response to food. When food is consumed, blood glucose rises. After digestion is complete, blood glucose falls. Sometimes it falls too low before rebounding to normal levels. A lower than normal dip signals hunger and causes cravings. Chromium may help control levels so they don’t dip too low after digestion. This ingredient is clinically proven with human studies. Their Probio5 supplement is a probiotic that supplies a proprietary enzyme and probiotic blend, grape seed extract, vitamin C and vitamin B6 that's supposed to help support overall health and body balance. Another product made by Whole Body Research, similar to the Plexus Probio5, is Keybiotics which contains 14 unique strains of beneficial bacteria to aid the digestive tract. Citrin K is another name for garcinia cambogia. While this ingredient is considered safe for most dieters, recent news links the ingredient to potential liver damage. There are many natural ingredients that CAN cause negative side effects, but that does not mean they will. Plexus Slim's FDA warning does concern us though. However, when it comes to weight loss supplements, there are safe ingredients known to be free of negative side effects that are clinically proven to boost weight loss, like green tea, that could be used in place of Citrin K. We found a few people wondering about Plexus Slim dangers, but we didn't find any indication via customer reviews that this is an issue. The official website for Plexus Slim offers a free trial packet. Plexus Slim Cost for the supplement are not listed on the official website, but dieters can join the website as a one-time buyer to gain access to prices. There are no clinical studies, but there are a number of Plexus Slim testimonials.
Plexus Slim Advantages
- Chromium may help control blood glucose levels to stop hunger and improve energy levels.
- Plexus Slim has a satisfactory BBB rating.
- A free sample is available.
Plexus Slim Disadvantages
- Citrin K may be linked to liver damage.(See Plexus Slim Side Effects)
- Only one proven ingredient is included in the supplement. (See Plexus Slim Ingredients)
ConclusionSo, what's the conclusion of our not-so-quick weight loss review? Plexus Slim is a powdered drink packet that adds weight loss ingredients to a bottle of water. It's rare you will find a fat burning powder, though they exist like plexus diet and Alphamine. The dieter may find the chromium helps to stave off hunger, but the remaining ingredients are not likely to promote weight loss. Another similar product taken before meals is Yacon Syrup, which is a syrup you can take with you anywhere, that is supposed to help you lose weight and feel better.
Plexus Slim Scientific Abstracts:
Green Coffee Bean Extract
The designed reasoning of the systemic research was to assess the efficacy of green coffee bean extract as a weight-loss supplement. The results of the meta-analysis showed a substantial difference in body weight with green coffee bean extract compared to those who had taken a placebo. (mean difference: −2.47 kg; 95%confidence interval: −4.23, −0.72). There was a moderate difference in effect and an active range of the studies. In conclusion, the outcome of the trials was reassuring. However, the methodological element of the studies was poor. More accurate testing is needed to ascertain the usefulness of green coffee bean extract (GCE) for weight-loss.
In additional results, suggestions were that GCE had a possibility of being useful in gaining weight and accumulating fat by limiting fat absorption and activating fat metabolism in the liver. In this study, the caffeine was found to suppress fat intake. Furthermore, chlorogenic acid was discovered being partly involved in the suppression, which in turn, reduced the hepatic TG level. 
Garcinia Cambogia Fruit Extract
The overall analysis uncovered an insignificant difference in weight-loss between HCA and those who were given a placebo, for HCA. (mean difference: −0.88 kg; 95% confidence interval: −1.75, −0.00). In one of the included studies, there were twice as many negative gastrointestinal issues than with the placebo. In conclusion, the suggestions are that Garcinia Cambogia extract can cause weight-loss in short-term. The overall effects were limited, and there is uncertain clinical importance. In the future, trials should be more detailed and contain more useful reporting. 
Alpha Lipoic Acid
Alpha Lipoic Acid (LA), which is also referred to as thioctic acid, is an essential cofactor for mitochondrial respiratory enzymes which boost mitochondrial function. It has already been reported that alpha-lipoic acid had a significant impact in reducing body weight gain in rodents, thus testing the effects of LA in obese human subjects was essential. The results were impactful, seeing the subjects lose substantially more weight than in those who were given a placebo (2.1%; 95% confidence interval, 1.4-2.8; P<.05). In this study, mild and transient urticaria and itchiness were the most typical negative reactions. In conclusion, there was a modest weight-loss effect in obese human subjects. Alpha-lipoic acid may be considered a supporting therapy for obesity. 
- 1. The Use of Green Coffee Extract as a Weight Loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials (2011). PubMed Central. October 14, 2016.
- 2. The Use of Garcinia Extract (Hydroxycitric Acid) as a Weight loss Supplement: A Systematic Review and Meta-Analysis of Randomised Clinical Trials (2011). National Center for Biotechnology Information (NCBI). October 14, 2016.
- 3. Effects of alpha-lipoic Acid on body weight in obese subjects (2011). National Center for Biotechnology Information (NCBI). October 14, 2016.