In our never-ending quest for that perfect diet product, this week we did some serious research and wrote this Plexus Slim review. Touted by one news station as the “Pink Drink Diet Craze,” we needed to know more about what’s behind the curtain. So, we looked closely at ingredients, side effects, and clinical evidence. Plus, we read hundreds of user comments from around the web. Then, we condensed that information to offer you the bottom line.
What is Plexus Slim Drink?
Plexus Slim is a weight-loss drink, also known as the “pink drink.” It’s a dissolvable powder that’s mixed with water, containing:
- Chromium Polynicotinate
- Green Coffee Bean
- Garcinia Cambogia
- Alpha Lipoic Acid
- Mulberry Fruit Extract
It’s made by the company, Plexus Worldwide Inc. and is said to produce weight-loss results without losing muscle. The blend of natural ingredients in Plexus Slim is exclusively manufactured to help lower blood sugar, cholesterol, and lipids – or so they say…
It’s also meant to help reduce appetite and cravings, as well as revamp one’s willpower over the foods they choose to eat. We want to trust this product and get behind the company, but some customer comments leave us wanting to investigate a bit more.
Plexus Slim Competitors
|Pruvit Keto OS||read|
|Yoli Better Body System||read|
|Burn HD (Sample offer)||read|
How did Plexus Slim start?
Plexus Worldwide Inc. was started in 2006 in Arizona. Since then, it has been growing exponentially and has made quite a name for itself, despite its high price tag.
Plexus Worldwide first started out with products to aid in breast health. Not long after their Breast Check Kit and Breast Cream (now known as Plexus Body Cream) had proved to be a success, they developed the Plexus Slim drink.
It was originally formulated to help balance blood sugar levels of Type 2 diabetes patients. Later in 2009, Plexus Slim was officially launched as a natural weight loss product to help individuals to lose weight by burning fat, not muscles.
Plexus Slim Claims
Like any other supplement companies, Plexus Slim also claims that their products are efficient and safe for your health. They claim that their products are the highest quality non-GMO, 100% vegetarian and gluten-free. They also boast that this product can regulate healthy blood sugar, blood pressure, and cholesterol levels.
In their official website’s Frequently Asked Questions, when asked about the scientific studies carried out on the Plexus Slim, they answered that:
- It develops the production of friendly microbes, called Akkermansia, which positively impacts disrupted metabolism linked with being overweight by 250 times.
- It develops the production of microbes, Lactobacillus by 365 times and Bifidobacterium by 290 times, which contribute to overall health.
- It develops fatty acids, butyrate, and propionate, which help regulate the metabolism.
- The claims are pretty hefty, so we expect some pretty hefty scientific research to back them up.
Plexus Slim Ingredients
Here’s where we dive into the ingredient of the product to determine whether there’s some evidence to back the claims – or if it’s just looking like another weight-loss flub.
Chromium (Chromium Polynicotiante)
Chromium is a fundamental mineral that has a crucial role in metabolizing carbs, fats, and proteins. According to some studies, chromium improves blood sugar control and insulin action in the body. Moreover, chromium has shown to aid in reducing people’s appetite and cravings for carbs. 
Garcinia Cambogia is a tropical fruit. Hydroxycitric acid or HCA, which is a natural substance, in Garcinia Cambogia is said to aid weight loss by making it harder for the body to store excess fat. This is done by obstructing the activity of the enzyme called citrate lyase, which is a fat-producing enzyme. In addition to this, it also helps in reducing one’s appetite by increasing levels of the hormone called serotonin in the brain.
The Journal of Obesity wrote that, “Garcinia extracts/HCA can cause short-term weight loss,” but go on to mention that, “The magnitude of the effect is small, and the clinical relevance is uncertain. Future trials should be more rigorous and better reported.”  
Green coffee is made of a chemical called chlorogenic acid. It is known for decreasing the number of carbs absorbed from the gut while eating. This results in lowering blood sugar and insulin levels. Therefore, proving to cause modest weight loss in some studies.
The Asian Pacific Journal of Tropical Medicine wrote that green coffee bean extract “has a potential anti-obesity effect with lowering body fat accumulation by regulating adipogenesis and lipid metabolism-related genes and proteins in WAT and liver.”  
Lipoic Acid (LA) is a crucial fatty acid in the metabolism of energy. We produce LA inside our body and it also naturally occurs in foods, so we do get a small amount from what we eat.
Studies suggest that LA has proved to reduce the levels of blood sugar and help diminish the indications of nerve damage in people that have diabetes.
Research also clarifies that LA supplements can reduce markers of inflammation linked to insulin resistance, liver disease, cancer, heart disease and several other health conditions. 
Xylooligosaccharide is well-known as a prebiotic that is claimed to support gut bacteria. Excerpted from wood, this sugar, is recognized as a better substitute for sweetener as it does not cause tooth decay. It’s a key active ingredient in Plexus Slim with a total of 1,000 mg per serving. 
Extract of Mulberry Fruit
This herb is known to aid in improving the circulation of lipids and cholesterol and is claimed to have cardiovascular health benefits.
BMC Complimentary and Alternative Medicine studied this fruit and concluded simply, “mulberry root bark exerts anti-inflammatory and anti-cancer activity.” Unfortunately, there isn’t a whole lot of research on this ingredient.  
Commonly used as a preservative, citric acid is great for clearing free radicals from the body, getting rid of kidney stones and maintaining acid levels in the body.
Does Plexus Slim Work?
According to some early researches, some of the ingredients in Plexus Slim may help you lose weight in the short term. The down side is, it’s unclear how much of these ingredients are present in Plexus Slim. On its website, where the label lists the product’s ingredients, the amounts of all the individual ingredients aren’t mentioned. Without knowing what the magic formula is, we can’t determine its efficacy. 
Plexus Slim Benefits and Results
This weight-loss product has gained popularity, in part, because its hefty claims. Let’s take a minute to see what some of the promised benefits of Plexus Slim are.
- Stabilizes blood sugar levels
- Prevents risk of cardiovascular disease and diabetes
- Helps in reducing cellular damage throughout the body
- Helps in maintaining healthy cholesterol levels
- Helps to reduce damage to nerve tissues
- Helps to reduce anxiety
- Helps to maintain inflammation issues
- Helps to burn fat
- Helps to control cravings by reducing appetite
- Improves insulin sensitivity
- Reduces depression
Before investing your money in any product, especially weight-loss supplements, it is always best to go through the customer reviews to get a better idea of individual experiences.
There are some reviews for Plexus Slim on Amazon and most of them had 5-star ratings. It turned out that they were written by some of the ambassadors for the product – which isn’t surprising. 
Details on Plexus Slim and Weight Loss
If you’re buying this product, chances are, you’re looking to achieve weight loss. One of the first questions we see popping up is, “will this work for weight loss?” We took an in-depth look into some of the main ingredients to see what science has to say about their weight-loss benefits.
The Journal of Alternative and Complimentary Evidence conducted a randomized, double-blind, placebo-controlled trial of 80 healthy, overweight adults, writing, “Supplementation of 1000 microg of chromium picolinate alone, and in combination with nutritional education, did not affect weight loss in this population of overweight adults. Response to chromium did not vary with central adiposity.” 
Green Coffee Bean
This ingredient has been researched a few times and it appears the caffeine in the green coffee bean can cause weight-loss.
Medicine and Science in Sports and Exercise stated that, “The additional 22% reduction in body weight, 25% reduction in epididymal fat-cell size, and 5 and 6% reductions in epididymal and retroperitoneal fat-pad weights, respectively, in the caf-ex group beyond the no caf-ex group support the hypothesis that fat loss with aerobic exercise can be increased when caffeine is ingested prior to the training sessions.” 
Is garcinia cambogia a legit weight-loss ingredient or a fad? Experts have found themselves on both sides of the fence here. While there is some research behind it, the results are virtually inconclusive and garcinia cambogia seems more and more like a fad ingredient than anything else. 
How to Take Plexus Slim
On their official website, it is recommended to drink Plexus Slim 1 to 2 times per day, by using the following methods to make it:
- Pour one packet of Plexus Slim into 12-20 ounces of water
- Shake well
- Drink 30-60 minutes before a meal
While using Plexus Slim, it’s very important to drink plentiful amounts of water. You need at least six or eight glasses of water every day. It’s hard to think of another supplement that calls for 8 glasses of water.
Potential Plexus Slim Side Effects
There’s a potential for negative side effects no matter what you take. Since everyone is different, there’s no telling how a person might react to any one supplement. Because of this, we took a peek at some of the known issues customers have had, as well as potential side effects of the individual ingredients in Plexus Slim.
Potential side effects, according to WebMD, are:
- Stomach irritation
When consumed in high amounts, Lipoic Acid has proven to have a much more destructive outcome. However, the quantity of Lipoic Acid in Plexus Slim is much lower than “dangerous amounts.”
Potential side effects of garcinia cambogia are:
- Weak and fuzzy feeling
- Skin rashes
- Brain fog
- Dry Mouth
- Digestive issues
WebMD lists some common side effects of Chromium:
Plexus Slim Product Warnings
Below, we’ve listed some of the product warnings linked to Plexus Slim.
- Do not use if you’re pregnant or you’re nursing.
- Do not use if your family has a history of having prostate cancer, prostate enlargement, heart disease, and low amounts of good cholesterol (HDL).
- Do not use if you’re a patient with GI tract disorders, such as ulcers, as you could experience extreme discomfort.
- Do not exceed the dose recommended on the label.
- Do not use if any indication of allergy appears. Stop the use immediately.
- Do not use if the product is without any label.
- Do not use if the product tampers in any way.
- Do not use if the seal is found to be broken or opened.
- Do not use if FDA does not approve it.
Make sure that you follow these things while using any health-related supplement from any company to avoid the potential side effects. If you want to, you can report the adverse effects on the site of FDA given below. They will review the complaints and act accordingly. 
Any Plexus Slim Lawsuits?
The FDA keeps an expanding list of weight-loss products that contain undeclared drugs or chemical ingredients. Just to clarify, Plexus Slim is not yet found on the FDA’s list – which is a positive sign.
There have been, however, some lawsuits reported against the Plexus Slim and some of their other products. Capsules and the 3-Day Trial pack of the Plexus Slim Accelerator have been banned in Australia since they include the unsaid and prohibited chemical 1,3-dimethylamylamine (DMAA). High blood pressure, bleeding in the brain and stroke are some of the dangers associated with this chemical’s consistent use.
As this drug is not approved for sale in Canada either, Health Canada is following up on this report as well. 
How Much Does Plexus Slim Cost?
Plexus Slim will run you around $82.95 with an “autoship” subscription. You’ll be billed automatically at the 15th of each month. You can also pay $87.95 for a one-time purchase of a 30-day supply.
It’s available for purchase through their official Plexus Slim website.
Other Plexus Products
Plexus Slim and Multi-Level Marketing
Since this company is MLM-based, we had to talk a bit about what this means. When a product is sold through “distributors,” it may very well rise in popularity and send a few products flying off the shelves for a little bit. This doesn’t always mean it works.
CNBC wrote, “In a bad economy, millions of people from around the world buy into these spectacular “income opportunities.” But critics like Robert Fitzpatrick say there’s a catch: chances of success are slim, and people who buy into multi-level marketing opportunities lose more than $10 billion every year.” 
Plexus Slim Alternatives
Where there’s a weight-loss supplement, there’s an alternative. In this case, we found several different options for those looking to lose some weight and get in shape.
- Feed on a balanced diet – lower your carbohydrate intake and eat quality fats and protein for a healthy way to lose weight. Try to get your nutrients from fresh produce, rather than artificial supplements that could come together with several side effects.
- Sporadic fasting – this fasting technique lets your digestive system to rest and activates your body to cut down fat while you are resting.
- A healthy lifestyle – target to lead a healthy lifestyle and support your body’s normal needs, rather than working against them.
If you are looking for another weight-loss supplement like Plexus Slim, you could check out Sensa. It’s a calorie-free powder that claims to stimulate the part of the brain that detects smells. This is claimed to help control appetite, so consumers feel fuller after a small meal. Also: read our Burn HD Weight-Loss Kit review »
The Bottom Line on Plexus Slim
Will Plexus Slim take you on a weight-loss journey you won’t ever forget? Will it eliminate your cravings and deliver a slimmer, healthier you? Make no mistake about it, we were initially intrigued by this product; it is the famous “Pink Drink,” after all. There are a few good ingredients in the formula, and we did find some positive comments, but there were too many negative issues for us to completely back it up.
Plexus Slim cons:
- Research tends to fall on both sides of the fence – for and against
- It is a multi-level marketing company, so you may have to find a distributor to buy a reasonable quantity of it
If you’d like to get rid of those extra pounds, we always suggest a product that combines scientific support, a good price, and a dedicated customer service team.
Among the best supplements we’ve seen this year is one called Burn HD. It’s formulated with a proprietary blend of four clinically-tested ingredients. Based on research, it’s been shown these can help spark metabolism, decrease hunger and boost fat loss.
User testimonials around the web are amazing. Burn HD is formulated with your success in mind and the company is so confident in it that they have a Special Trial Offer going on right now. That’s pretty amazing.Learn More About Burn HD »