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Isotonix Review - 14 Things You Need to Know

Isotonix offers you the maximum benefit from vitamins and nutrients. The company’s supplements range from weight loss aids to wellness products and multivitamins. We soon discovered they all come with a considerable price tag, however, making it a poor option for those trying to stay on budget.

Most of their products range from $60-100+, and our researchers found many cheaper alternatives on the market. In the bottom line, though, we gave them the benefit of the doubt and compared Isotonix’s “quality” ingredients to their product claims to see if this company is worth investing in.

Isotonix can be purchased through their Official Site.

Isotonix Readers: Noom is offering our readers a risk-free trial, for a limited time. Click here for more information!

What is Isotonix?

Isotonix claims to be the world’s most advanced nutraceutical that provides supplements made of the highest quality natural ingredients. The products include scientifically advanced formulas designed to ensure that your body receives the essential vitamins, minerals, and nutrients required for long-term health and optimal nutrition. It manufactures four essential supplements: Isotonix OPC-3®, Isotonix Multivitamin, Isotonix Activated B-Complex, and Isotonix Calcium Plus.

These supplements are multivitamins and minerals, but do we really need to supplement or is food a better option?

  • Advanced Pharmaceutical Bulletin – “The consumption of a daily multivitamin among people all over the world is dramatically increasing in recent years. Most of the people believe that if vitamins are not effective, at least they are safe. However, the long term health consequences of vitamins consumption are unknown.”
  • Europe PMC – “… self-medication with vitamins, minerals or FSs shows a high user prevalence which has increased significantly over time. In light of potential interactions with prescribed medicines the results show the importance of ascertaining self-medication with vitamins, minerals and FSs in medical practice.”
  • Archives of Public Health – “The adequacy of micronutrient intake is a public health concern, as both insufficient and excessive intake levels may result in adverse health effects.”

Isotonix Competitors

Plexus Slim
Usana Essentials Multivitamin
Other similar products: , NeoCell, ,
Company Bio

How Did Isotonix Start?

Market America, a product brokerage and internet marketing company, was founded in 1992 by JR and Loren Ridinger. Its headquarters is in Greensboro, N.C. and the Company employs over 650 people as of 2010.

The firm manufactures various products such as dietary supplements, cosmetics, auto care, jewelry, household cleaning supplies, personal care products, custom websites, water purifiers, and weight management products.

In 1993, it started manufacturing Isotonix products and had been manufacturing them since then.

Market America operates as a multi-level-marketing (MLM) business.

Market American Shop.com earned an “A+” rating with the BBB along with 4.45 out of 5 stars based on an average of 29 customer reviews. They’ve closed 14 complaints customers lodged with the BBB in the past three years.

Isotonix Customer Testimonials

Isotonix Claims

Isotonix supplements claim to provide your body with the maximum benefit it can receive from vitamins and minerals. It offers a complete array of multivitamins, weight loss supplements, and wellness products, which will fit your needs and provide unique health benefits.

How Does It Work?

How Does Isotonix Work?

The term Isotonic refers to having the “same pressure.” That means that its chemical makeup is similar to your body’s plasma, blood, and tears.

Hence, all fluids in your body have a particular concentration, referred to as ‘osmotic pressure.’

The body’s standard osmotic pressure is isotonic.

According to this logic, a substance entering the body must be in the isotonic state to be absorbed, transported, and readily available for its metabolism.

Isotonix dietary supplements come in an isotonic solution. Unlike pills that take time to disintegrate, and for their contents to be fully dissolved and transformed into the proper isotonic state.

During this time, much of their activity is lost. During digestion, the essential micronutrients in pills and capsules can get trapped by fats, fibers, tannins, or inactivated by the stomach’s highly acidic pH level.

However, Isotonix supplements are already in disintegrated powdered form. This means that less work is required to obtain maximum absorption, and therefore, the nutrients are transported directly into the small intestine and quickly absorbed into the bloodstream.

When the Isotonix products are consumed in this fashion, the supplements do not lose their nutritional value and make the absorption of nutrients highly efficient while delivering maximum results.


Isotonix Ingredients

isotonix ingredients

Isotonix consists of all-natural ingredients that include:

Grape Seed

According to Antioxidants, grape seed extract is typically taken from the seeds of red grapes (instead of white), which contain high levels of oligomeric proanthocyanidins (OPCs) complexes. Grape seed extract is extremely rich in antioxidants.

It contains the polyphenol-a compound, with high antioxidant activity.

Red Wine Extract

Red wine extract is a powerful antioxidant that is present in seeds, stalks, vines, and roots of grapes, with the highest concentration in the skins. This is because it contains resveratrol, per Biomedicines

The antioxidant properties of red wine extract can help to maintain healthy circulation by strengthening capillaries, arteries, and veins, according to Molecules.

Drugs.com reports that Resveratrol present in red wine extract help enhance memory and enhance joint mobility.

Pine Bark

Pine bark extract is an all-natural combination of procyanidins, bioflavonoids and organic acids, per Frontiers in Psychology. Most importantly it consists of a potent antioxidant compound called pycnogenol.

The extract’s antioxidant properties selectively bind to collagen and elastin and promote the production of endothelial nitric oxide, which is responsible for the dilation of blood vessels.

It also helps support healthy blood platelet activity, alleviates menstrual cramping and abdominal pain, maintains joint flexibility, ensures healthy sperm production supports a healthy complexion.


Bilberry extract is derived from the bilberry plant that has bright green leaves and bell-shaped flowers and is grown in northern Europe, per Herbal Medicine. It is closely related to blueberry, huckleberry, and cranberry.

It is rich in pigments known as anthocyanins, which are powerful antioxidants.

Scientific studies confirm that bilberry extract supports healthy vision and venous circulation, per Molecules


Citrus contains disease-fighting antioxidants called bioflavonoids. According to Food Chemistry, they are scientifically proven to help maintain healthy circulation, reduce obesity and demonstrate anti-inflammatory activity.

Weight Loss

Isotonix and Weight Loss

isotonix weight loss

Isotonix supplements consist of all-natural ingredients that help you to achieve long-term health and fitness goals. They do not contain any ingredients that cause weight gain or stimulate hunger cravings.

The multivitamin supplement provides you with the right amount of nutrients that your body requires. It helps boost your metabolism, providing you with a healthy skeletal system and muscle contractions while increasing your energy level.

Hence, you can enjoy your workout sessions for a longer period and trim down your fat quickly, without easily feeling tired or fatigued.

All of the Isotonix products have the following properties in common:

  • Gluten-Free
  • No detectable GMOs
  • No artificial preservatives
  • No Fillers
  • Vegetarian
  • Isotonic-Drinkable supplements

Isotonix supplement products include:

Isotonix OPC-3®-Single Bottle (30 Servings)

Isotonix OPC-3 is a dietary supplement that contains some of the most potent bioflavonoids currently known to research scientists.

The purest and best-researched OPCs have extracted bilberries, grape seed, and red wine.

Pycnogenol, a powerful antioxidant, is extracted from citrus fruit and pine bark.

Isotonix OPC-3 has been shown to provide a variety of health benefits including, but not limited to:

  • Combating free radicals
  • Showing anti-inflammatory activity
  • Maintaining healthy circulation
  • Strengthening capillaries, arteries, and veins
  • Alleviating menstrual cramping
  • Supporting visual health/visual activity
  • Promoting healthy blood vessel dilation
  • Boosting healthy nitric oxide levels
  • Supports a healthy skin complexion
  • Promoting healthy platelet activity
  • Promoting healthy sperm quality

Isotonix Multivitamin with Iron-Single Bottle (30 Servings)

All-Natural Isotonic Multivitamin contains 100%, or more, of the recommended daily value of essential vitamins and minerals. Hence providing you with the maximum nutrients that your body will require while replacing dietary deficiencies. It offers a wide array of health benefits that include:

  • Enhancing normal cognitive activity
  • Promoting skeletal, muscular & skin health
  • Promoting the conversion of food into energy
  • Fostering healthy growth and repair of tissue
  • Actively metabolizing fats and carbohydrates to support fat loss
  • Supporting a robust cardiovascular system
  • Supporting strong bones

Isotonix Activated B-Complex-Single Bottle (30 Servings)

This supplement contains high vitamin B6, B12, and folic acid levels, which boost your body’s vitamin B levels. As a result, offering you a wide array of health benefits that include:

  • Increasing energy and fuelling optimal energy production
  • Promoting a healthy nervous system, bone marrow, and intestinal tract
  • Regulating healthy levels of serotonin, hence decreasing stress and improving mood

Isotonix Calcium Plus-Single Bottle (90 Servings)

This supplement contains high levels of calcium that is essential for:

  • Maintaining strong bones, healthy teeth, and gums
  • Supporting skeletal health
  • Promoting normal regulation of enzyme and hormone production

Some other popular Isotonix products include:

  • Isotonix Digestive Enzymes with Probiotics
  • MochaTonix
  • Isotonix Daily Essentials Kit
  • Isotonix Complete Greens
  • Isotonix Essentials Turn Up
  • Isotonix Peak Performance Blend

Superior Quality of Isotonix Products

All the raw materials used to manufacture Isotonix are verified and require a Certificate of Analysis (COA) to be approved. Raw materials that pass this step are subjected to laboratory confirmation of physical characteristics and material potency, followed by microbiological contamination and heavy metals detection.

Each Isotonix product is then carefully prepared, and all of its manufacturing records are in written format. Every batch is carefully reviewed and approved by Market America’s highly trained quality control personnel. Audits are conducted at the warehouse to detect any damage and confirm label accuracy, appearance, taste, and identity before selling it.

Each production facility is required to meet GMP (Good Manufacturing Practice) standards by regular monitoring and is approved by either the Food and Drug Administration or the United States Department of Agriculture for their strict adherence to Standard Operating Procedures, employee training, product specifications, and supplier/vendor qualification procedures.

Benefits and Results

Isotonix Benefits and Results

isotonix benefits

Isotonix supplements consist of a combination of several ingredients that offer unique health benefits regarding energy, immunity, muscle mass growth, and digestion.

It is popular amongst athletes and people who want to get rid of their never-ending fat belly. Many users take it before work out sessions as it boosts their energy levels and provides them with maximum strength and stamina.

A high quantity of vitamins provides you with increased immunity against diseases and boosts your overall metabolism.

It is also a beneficial supplement for older people. It helps them manage daily tasks without any complaints about muscle contractions and feeling fatigued, hence providing a healthy lifestyle for people of all ages.


How to Use (Take) Isotonix

All Isotonix supplements come in powdered form and mixed with water before drinking.

To ensure that the isotonic solution flows immediately into your small intestine, make sure you take it on an empty stomach.

This process utilizes the supplement more efficiently due to the increased absorbability, hence giving optimum desired results.

Why is Gastric Emptying Time Stressed When Talking about Isotonix?

Nutrients that are already isotonic will not be broken into an isotonic state. Therefore, gastric emptying occurs more rapidly. Biological sensors in the gastrointestinal tract detect that the ingested solution is isotonic and at a correct pH. This causes the pyloric valve at the lower end of the stomach to remain open, allowing the concentrated solution to be squirted into the small intestine by stomach contractions. Absorption of the nutrients by the intestinal mucosa then starts to occur.

Isotonix products are to clear your stomach at an optimal rate to maximize absorption. A pill does not fully deliver into your bloodstream the vitamins it holds within. Either the medication is dumped whole into your intestinal tract or the active ingredients pass through without being fully absorbed.

Vitamins taken in isotonic form do not have these shortcomings. Thus, it is necessary to consume Isotonix supplements on an empty stomach.

Product Warnings

Isotonix Product Warnings

Isotonix products are free of harmful chemicals, preservatives, and alcohol.

For optimum results, stick to taking Isotonix with water. Avoid mixing it with soda, milk, juice, coffee, tea, etc. It should be stored in a dry and cool place, ideally in a dry cabinet.

Avoid keeping it in your bathroom and keep out of children’s reach. If you are storing it in the kitchen, make sure it is far away from the sink, stove, window ledges, and heat-generating appliances.

If the weather conditions are very humid, you may keep it in the refrigerator but far from the fruit and vegetable area because it has high humidity. Note that moisture from the air quickly condenses on cold items taken out from a refrigerator.

The supplement’s sugars quickly absorb moisture and cause hardening of the power, commonly referred to as ‘caking.’

Return Isotonix products immediately back into the refrigerator after using it.

Ensure you clean and dry the screw cap’s threads before putting the bottle back into the refrigerator. Any amount of moisture will accumulate on the bottle resulting in caking. Ensure the cap screw is tightly closed at all times and avoid leaving it open for more than a few minutes.

If you note that the powder is hardening, shake the bottle contents a few times during the cool-down period. This will help prevent it from hardening into a solid mass.


Any Isotonix Lawsuits?

isotonix lawsuits

In 1999, Market America and its CEO faced certain charges imposed by the United States Security and Exchange Commission concerning how the Company started in 1994. The Company was thought to be selling unregistered Market America stock.
However, the case settled after Market America paid a hefty fine of $100,000 and $235,498 to the SEC. The firm did not admit or deny any of the allegations. In 2001, the firm’s CEO settled to avoid any future violations of the federal securities laws, and the Company went private.

On March 3, 2006, Steve Sawyer sued Market America to pay him for $8,333.34 in monthly services and a $25,000 bonus.

In 2007, the court ruled in favor of Sawyer’s claim that Market America went against the North Carolina Wage and Hour Act by violating its workers’ rights. Sawyer appealed to the North Carolina Court of Appeals, which ruled the trial court’s decision in favor of Market America in June 2008.

Sawyer appealed to the North Carolina Supreme Court and was denied review on December 11, 2008.

Based on the same facts as the North Carolina lawsuit, Sawyer filed a lawsuit against the firm in Multnomah County, Oregon, on December 26, 2008.

Moving into 2009, Market America decided to take the North Carolina lawsuit to trial. Sawyer filed a motion to stay the North Carolina lawsuit, which the judge granted.

Later that year, Market America filed a motion to stay the Oregon lawsuit, which the judge granted. In 2010, Sawyer saw a denial for the review to keep the Oregon Supreme Court’s Oregon lawsuit.

In a 2017 federal lawsuit, a party accused Market America of violating the Racketeering Influenced and Corrupt Organizations Act and California state law.

The suit claims that the Company is very biased and targets only Chinese-American immigrants for their own money-making business.

By doing this, it aims to sell products to their friends and relatives in Asia. The lawsuit characterized Market America’s business practice as “racketeering.” It accused that “while the executives tell distributors they can earn more than $560,000, only those at the top make that kind of money. Ninety percent of sellers do not receive a penny”.

On May 13, 2019, Chuanjie Yang sued Market America in a class-action lawsuit for acting like a pyramid scheme, according to Class Action.

February 2020 also saw a new accusation from the FDA. A warning letter, sent to COO Marc Ashley, spoke of a failure to report adverse effects. It also brought up issues with label compliance for several of their products. We will be keeping an eye on any upcoming updates regarding the warning letter.


Isotonix Alternatives

Many other companies produce a similar product to Isotonix, as listed below. They all contain natural, high-quality ingredients, ideal for achieving your targeted weight loss and fitness goals.

They do this by suppressing appetite and providing an explosive amount of energy to users to perform intense physical activity and workouts without feeling hungry or tired.

Following is a quick list of some of the best-related diet pills:

  • Phenocal
  • PhenQ
  • Lipozene
  • Slim Optimum
  • Adiphene
  • Lipozene
Customer Service

Customer Service Contact Info

  • Address: Market America 1302 Pleasant Ridge Road Greensboro, NC, 27409
  • Phone: (866) 420-1709
  • Email addresses: info@marketamerica.com and customerservice@shop.com
What Users Are Saying

What Users Are Saying

“I have been off and on OPC-3 for the better part of a decade. I have noticed improved circulatory function and just a good feeling.”

“Even if I took a double dose of this, it would not supply the recommended daily dose of calcium for a woman. Very disappointed that I didn’t check the label before purchasing this item. The taste is palatable.”

“Tangy tasty multivitamin to energize you while providing nutritional benefits.”

Bottom Line

The Bottom Line on Isotonix

So, the last of the facts have trickled in. What’s our take on this one? We like the fact that Isotonix has been on the market for over ten years and that it seems to have developed a cult-like following. We also like the results that some users have seen and that the product is readily available, but we have reservations recommending this because of the more affordable alternatives on the market that accomplish the exact results. We’re also concerned about the inconvenience of mixing the powders.

If you’d like a convenient, affordable way to lose, we suggest a program that provides healthy and steady weight-loss and is backed by multiple clinical studies.

Among the best programs we’ve seen this year is one called Noom. This weight loss system provides its users with everything they need to start losing weight the right way, like human coaching, personalized meal plans, and support groups.

The makers of Noom are currently offering Dietspotlight readers a  free trial offer, which is a sign that they’re confident in their program.

Learn More About Noom »
Isotonix Review
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What is Isotonix multivitamin?

The Isotonix multivitamin is a preparation of vitamins and dietary minerals. It is available with or without iron added.

What is Isotonix digestive enzymes good for?

The Isotonix Digestive Enzyme formula helps control cholesterol levels, supports a healthy gastrointestinal tract and immune system, aids in digestion and in the absorption of nutrients.

What are the side effects of Isotonix?

Isotonix products side effects may include headaches.

What are the ingredients in Isotonix?

Some of the ingredients found in Isotonix products are chromium, l-carnitine, pycnogenol, resveratrol, acai, coenzyme Q10, vitamins, minerals and lutein. The formulas differ depending on the supplement.

Does Isotonix work?

There are no scientific studies linking Isotonix to weight-loss. We did find research into some active ingredients, like chromium, but that ingredient is used in other products.

Where can I buy Isotonix?

Isotonix can be purchased using their Official Site.

How much does Isotonix cost?

Isotonix costs vary by supplement. The Isotonix® Magnesium costs $41.95. You can also find  MochaTonix® (Fat Burning. Nutrient Enhancing. Energy Boosting), for $39.95.

How should I take Isotonix?

You should take Isotonix based on the supplement purchased.

Do Isotonix products contain soy?

Yes, several of the Isotonix products contain soy.

Does Isotonix come with a guarantee?

Isotonix comes with a guarantee. You’ll receive a return authorization and send the unopened item back for a full refund.

Is Isotonix FDA approved?

Isotonix products are not approved by the FDA.

Are Isotonix vitamins any good?

Vitamins in general may be able to help balance out nutritional deficiencies you may have with your diet.

62 Isotonix Reviews

  • Wants to know the soy content

    do any of your products contsin soy?

    • Karen (Editor)

      Hi Milly. From what we’ve found no however they do have a several many products.

  • maureen

    Are there any side effects from taking these vitamins?

    • Dale

      The products provide supplemental nutrients, there are no side effects because all the ingredients are natural extracts from fruits, vegetables and certain tree barks rather than chemical based pharmaceuticals that have various side effects.

      • Cynthia

        What’s up with the Fructose and Glucose in the product? I must admit the product works for weight loss but I’m concerned about those two chemicals especially…..

        • Glenn Ewald

          Some people are concerned about these two ingediants, however, if you can eat a handful of grapes a day and survive then you will not have a problem with Isotonix. Understanding the delivery system of Isotonix wherein the product is not digested but ingested already in an isotonic state, the product is dumped into the small intestine within 5-8 minutes. This unique delivery system provides 95% bioavailability within 15 minutes. So whats the fructose and glucose for. Micronutrients need a “taxi cab” to get them to their destination. Fructose and Glucose are the taxi cabs. I have been taking these products for over 10 years now and have researched and studied them extensively. Hope this helps

      • john

        Dale, with all due respect, how can you possibly say this with certainty? Of course supplements, even naturally derived, can have side effects. We are not all made the same. The way we process supplements is not the same.

  • barbara

    Tell us Ive been having really soft stool lately and was wondering if anyone else is having this problem.

    • Summer (Editor)

      Has anyone had this same experience?? Is this still a problem Barbara? If so, might want to discontinue using this product and try another one. How about Dietspotlight Burn, let us know how it goes. It’s ingredients are pure and clinically proven.

    • Glenn Ewald

      Certain people may experience this when first beginning on Isotonix products. The reason for this is twofold. First is that of a cleansing effect. The second is that because of the delivery system, wherein the product is ingested in an isotonic state and therefore is not digested but dumped into the small intestine within 5-8 minutes, the normal functions of the body may not be use to this at first and when the duodenum, the valve going from the stomach to the small intestine, opens then everything opens…. If you catch my drift. Please continue your Isotonix. It will be worth it

  • SSPC

    I will have a diarrhea after drinking isotonix opc3 beauty blend. I have lactose intolerance. Does it have lactose? I don’t have any issue with opc3,trying to find out what makes me sick.

  • Mike M

    are there any interactions with isotonix powdered vitamin and Lipitor and BP meds?

    • Adrian (Editor)

      Hi Mike! Because of possible interactions with medications and other products, please make sure to consult with your physician before taking this product.

  • Peggy

    I need someone to tell me if there is any soy or tree nuts so ANY type in the products by isotonix ?

  • Best time to take it
    John Blue (Verified Purchase)

    When is the best time of day to Isotonix digestive powder.

    • Dale

      If you’re referring to the digestive enzymes, take it after having a meal.

      • Your Name

        Opc-3 is supposed be taken 1/2 hour BEFORE YOU EATTell us your thoughts about Isotonix .

    • Maribel (Editor)

      Hi John. you should take Isotonix based on the supplement purchased. A substitute product to consider is Dietspotlight Burn. Many users report experiencing results and its fairly inexpensive.

  • Keri

    I’ve been on Isogenix and Isonix for over a month. There are side effects. I am losing weight but on full weight loss program. The Isonix has improved my sleeping 10 fold. After taking it I feel as if I have taken a sleeping pill. I am also having lots of dreams. very busy ones. I have normally low blood pressure due to a heart valve issue. With isonix I have found some mornings I am really experiencing a major blood pressure low. My chest feels heavy and I feel almost ‘compressed’ breathing. Also in week 5 I have begun feeling numb down one side of my body from my should to my foot. Pins and Needles and pain all down one side. I was concerned that this could be affecting my heart, as it seems to be indicating that this is happening. I take Isonix in a shot (liquid form) I am not taking any other medications. So does Isonix lower the heart rate and blood pressure? Is this what is causing this side effect? I also wake up with morning dull headaches. This does improve when I take the Isogenix acclerator and have my shake tho.

    • wendi

      go to the doctor

    • Cameron Mael

      Uh…it helps you sleep??? You are supposed to take this when you first get up, on an empty stomach, a half hour before “anything” else…including coffee. There is a science to this product, with very specific instructions…you have to adhere to them for the science to work.

  • Virginia

    I’ve been having nightmares since I started taking Isotonix Opc-3 a couple of weeks ago. I usually never dream or remember having a dream, but now i almost every day have nightmares.

  • Norma

    I tried opc3 and made my stomach burn and made me tingly. Stoped taking it and took a while to recuperate

    • Adrian (Editor)

      Hello. All users are different and can experience different results; please make sure to consult with your physician before continuing this product to make sure its safe and effective for you to use.

  • Eric

    Has anybody had a bad case of acid reflux after taking isotonix vitamins.
    I tried the multiple vitamin twice over 6 months and both times after about 3 weeks, I lost the taste in my and got acid reflux

    • Adrian (Editor)

      Hi Eric! All users are different and can experience different side effects; please make sure to consult with your physician before taking this product again.

  • Your NameHEATHER


  • Alex

    I was wondering if anyone has taken the activated B Complex, and if so did they have side effects, or any negative issues?

    • Stephen (Editor)

      Anyone had issues?

      • Brandy

        The B-Complex changed my life. I had more energy and it helped to calm stress unbelievably! B vitamins are depleted with stress and sugar. 🙁 I have and love both! I absolutely love isotonix and take many of the other supplements as well.

    • YC

      Activitated B change my life .I had severe migraine for more than 25year. ( Didn’t know that I am a B deficiency.)
      I never believed in supplements as it give me migraine when I take them. I was amazed that my migraine instantly lifted in 20 min after 2 doze , in the past I be down for at least 3 day. I am migraine free now. After 1 year on ( essential kit ) l look ten year younger.

    • Sharon

      I’ve been taking the activated b complex for a little over a week. I definitely feel better and my hair seems healthier and I go through my day with less cravings and less of an appetite, however I have had significant insomnia every night. I need to talk to my Dr about whether to continue using or not.

  • Contains Cobalt or Chromium
    Mike Thanasoulis (Verified Purchase)

    I v e been taking this for close to ten years along with the acai.I was told by Dr. to sop taking the Acai because of the Chromium/Cobalt in it.I have high levels in the blood due to Metal on Metal hip replacements.My Question is does the OPC3 have any Cobalt or Chromium in it? I would like to keep taking it.I do miss the Acai.And would like to continue taking the OPC3. But not if it Contains Cobalt or Chromium.Thank You

    • Stephen (Editor)

      It seems the formulation consist of Natural fruit extracts and flavonoids; no mention of metals like cobalt or Chromium, Mike!

      • nancy dambrosio

        yes i checked the ingredients and it does contain Chromium.

    • Judy

      Isotonix OPC 3 has no cobalt or chromium. It contains Grapeseed extract, Bilberry extract, and Pinebark extract. A powerful antioxidant. Look it up on Istonix.com for the ingredient list. A terrific product with many benefits.

  • Is this safe for people with Diabetes?

    Are Isotonix supplements safe for diabetics? I take Ultimate Longevity Formula and Maximum ORAC. They both VERY sweet.
    Ultimate Longevity formula contains soy. Soy is not organic,is it?

    • Juli

      Soy can be organic. I believe (which can be verified if you call there 800 number and speak to product specialist) they use the highest quality they can find that isn’t registered legally as ‘Organic’, however.

  • Is this good? Any side effects?
    Michelle Romaniszyn

    Hello. I recently sat in on a presentation on Isotonix Opc-3 and is benefits on your health as well as nutritional supplements and other products. My question is, Is this really a good product and are there any severe side affects. I don’t want to spend alot of money on something that isnt any different from another detox system. I am looking to detox my body, rather cleanse my body of toxins. I’ve never had a cleaning done before. What are your thoughts?

  • Which is the best for me?

    Isotonix was recommended to me and I’ve been doing some research on the product, but still have questions. I’ve suffered from acid reflux for quite some time, but lately, it was gotten really bad. One doctor thinks it could be the start of an ulcer and wants me to have an upper GI endoscopy. However, before opting you have then shoe a camera down my throat, I’d like to try Isotonix, as I’ve read excellent reviews about the product. My question is though, which one works best for acid refux..the digestive health or the OPC-3? I’ve also read about people taking the OPC-3 along with aloe vera juice. There are so many choices, I don’t know which one to go with. Please help me!! I need relief asap.

    • Jeannie

      Hello, I was introduced to opc3 3 years go because of acid reflux any food I eat will have a burning like feeling. I started taking it after one week I didn’t feel the burning in my chest.Awesome but it didn’t stop there I was sleeping better. I feel great. It help me so much I am happy.
      Isotonix .

      • Phoebe

        Full disclosure here: I sell Isotonix.. but only after taking OPC-3 for a few months and finally getting off the allergy meds I had used since I was a teenager. Since then, they’ve helped my mom reduce her high-blood pressure meds, helped my husband with joint pain, helped a friend with acid reflux and countless other benefits as a natural anti-inflammatory. I think it is expensive – but you get what you pay for – they have 3rd party quality control which means that you can trust what is on the label is IN the bottle…. (not true for MANY other companies (did you watch the Frontline piece out in Jan? Yikes.)

      • Anonymous

        I was taking 7 pills a day for acid reflux and started taking the aloe product. I am not taking anything anymore. I love the ultimate aloe

    • Your Name

      OPC and Market America’s other vitamins made my acid reflux worse

      • Lydia

        Try Ultimate Aloe juice, pls.

    • Maggie

      Definitely try the digestive enzymes and the ultimate aloe! Sometimes the other Isotonix can cause acid reflux, but it really is a case-by-case trial. If I take them on an empty stomach then they always give me acid reflux. I would only recommend the digestive enzymes and the ultimate aloe until you start to see some results.

    • Jeng

      Take the aloe juice

  • Weight Increase Side Effects
    Janet Lee (Verified Purchase)

    May I know is weight increase a side effect after taking isotonix. I have started for about 2 months. Tks

    • Dale

      The products provide supplemental nutrients, there are no side effects.

    • Tina

      I’ve been taking the powder packets daily for a month. First, my energy level increased tremendously, Second my joint pain decreased to non-existent, Third, my inflammation is much better and I’m losing a bit of weight. I recommend it to everyone I meet. OPC3, multivitamin, b-complex and calcium-plus are all in one packet. I disagree that the price it too high when I get these results! I sip it down with my big bottle of water at work. And I take it on usually on a full stomach – doesn’t seem to make a difference. No acid reflux or upset stomach. I’m an advocate!!! GET THIS STUFF – especially if you’re older and creaky!

  • Felt Some Side Effects
    William Thompson (Verified Purchase)

    I committed to myself and my wife to lose weight and take the Isotonixs she purchased for me. However, after taking this stuff for several days, I had to quit. I agreed to continue the diet, but each time I took this stuff, I felt a lot of pressure in my head, couldn’t focus my thoughts, felt dizzy, and my vision went somewhat out of focus. So much for Market America. I wish she could receive a refund. She spent several hundred dollars.

    • Dale

      What products are you taking, what portion sizes are you taking and how does your wife feel when she takes the products? If you are by any chance allergic to a product you can get a bad reaction such as what you’re describing and it doesn’t mean the product is bad since no one else is having the same reaction. The products are made from natural fruit, and vegetable extracts but some people do have food allergies so your claim cannot be discounted, the solution is to determine what you’re reacting to.

    • Est

      I too have noticed the blurry vision and dizziness after taking opc-3. I had to pull books away from my eyes to see the lettering right. And had that feeling you get when you are a tad congested in the head and a little flush and fuzzy. Today will be day 3 and I am going test if I get the same reaction after taking it. If so I’m returning.

  • Madi (Verified Purchase)

    I took isotonix for 1 month and I gained 4 lbs instead of losing. Should I continue or stop taking?It worked for my friend, I am not sure why it’s not working for me. It’s expensive and I have 1 more sealed bottle.

    • Victoria (Editor)

      Hi Madi! We’re sorry you weren’t able to achieve the results that you wanted from Isotonix. Have you looked into other weight-loss products? You should check out !

    • Victoria (Editor)

      Hi Madi! We’re sorry that you weren’t able to achieve the weight-loss results you wanted from Isotonix. Have you checked out Burn HD?

    • Rick

      Isotonix is not a weight loss regiment, but rather a dietary supplement to give your body, in a very high absorbable format, needed vitamins and minerals that our diets don’t or can’t provide. It is possible to lose weight using Isotonix, depending on your body, but that’s not what they are geared for. If you’re interested in losing weight, talk to who supplies your Isotonix for what products are geared for weight loss. If they can’t help you any further, find a new distributor.

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