Updated: 11/17/2017

CholestOff Review - Does This Dietary Supplement Work?


Why are people talking about CholestOff? We decided to take a closer look at the ingredients, side effects, clinical research and customer service quality. Additionally, we read hundreds of user reviews and complaints online. Then, we summarized and condensed to give you the info you need.

CholestOff Readers: Click here to find out why we're giving away samples of our product, Burn HD.

What is CholestOff?

First off, CholestOff ingredients are plant sterols/stanols 900mg, vitamins and minerals. It promotes wellness by lowering cholesterol levels and improving heart health. The recommended serving is two capsules, twice per day. One benefit is that you can take on-the-go.

CholestOff is manufactured by Nature Made, a company that’s been operating for more than 40 years. The supplement is available through trusted retailers and local grocery stores. We like that it contains a natural ingredient and that we located some positive customer comments, but read on…

Products Similar to CholestOff

Lack of Results – “No Weight Loss?”

The first concern was the lack of results from CholestOff ingredients. “This supplement is linked to reducing cholesterol and improving overall wellness,” said our Research Editor. “So if you’re looking to lose weight, this product probably isn’t the best way to reach your goals.”

“I saw minor improvement in my bad cholesterol, but I didn’t lose any weight,” said a user.

“No weight loss at all, extremely disappointed,” said another.

Some users did see manage to lose weight while using CholestOff. “I believe that Cholestoff and healthy eating improved my weight-loss,” commented a dieter.

CholestOff Side Effects – “Concerning?”

Several reviewers online mentioned CholestOff side effects being a cause of concern. “With CholestOff, I’ve been having joint pain and discomfort,” said one customer.

“This stuff has led to constipation for me; I won’t buy again,” said another.

I developed the same side effects that I had while taking the Statins. The side effects consisted of severe and debilitating muscle cramps,” commented a user.

We noticed not every customer experienced the same effect while using CholestOff. “I experienced no side effects (I lost some weight but I’m not sure there’s a direct connection),” said a customer.

“Safe and effective I have been using it for years. No side effects ,” reported a consumer.

We’ve discovered that when a particular part of a dietary supplement is considered troublesome, like causing adverse reactions, the likelihood of long-term success is slim. If CholestOff causes negative side effects for some customers, it could make it difficult for dieters to reach their goals.

The Science – “Researched?”

We’re encouraged by the science behind CholestOff. There are several studies showing the key ingredients help lower cholesterol levels and improving overall health and wellness. Unfortunately, when it comes to weight-loss, there doesn’t seem to be any clinical studies. At DietSpotlight, science-based facts are a critical part of the review process. Without evidence that a product is effective for weight loss, we’re skeptical about it.

What Users Are Saying

"”I started using this a few years ago when my doctor was going to put me “on pills for life.” I started a diet and exercise program and these pills along with Nature Made Triple Omega. A month later my doctor said he did not know what I had been doing but keep it up because all of my labs were within normal limits and improving. This stuff works but you do have to do your part as well. Get off the couch, eat better and exercise a few times per week.”"

"”The pills are huge and hard for me to swallow, but I didn’t experience any side effects. There wasn’t a horrible taste or after taste.”"

"”For whatever reason, make my heart beats faster, had to stop it.”"

The Bottom Line – Does CholestOff Work?

Are you heading out the door for a bottle of CholestOff? Well, we like that it contains some clinically-tested ingredients and is located in a variety of locations, but we’re a bit concerned about this one because the research doesn’t relate to weight-loss. Also, we’re hesitant about it due to lack of results and negative side effects.

If you’re looking to improve overall health and increase weight-loss, we suggest going with a supplement that provides more bang for your buck and scientific evidence that proves it works.

Among the best products we’ve seen this year is one called Dietspotlight Burn. The clinically-tested formula of four ingredients has been shown to help burn fat and boost metabolism. We’ve read hundreds of user reviews and comments and people are seeing great results without harmful side effects.

Also, the makers of Dietspotlight Burn  are offering customers a special trial offer, which is a sign of confidence in their product.

Learn More About Burn HD »
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What are the side effects of CholestOff?

CholestOff side effects could include bloating, indigestion, gas, and stomach pain.

What are the ingredients in CholestOff?

CholestOff ingredients are Plant Sterols/Stanols (Pine Tree), Calcium Carbonate, Tribasic Calcium Phosphate, Croscarmellose Sodium, Hydroxypropyl Methylcellulose, Silicon Dioxide, Magnesium Stearate, Color Added, Polyethylene Glycol, Triethyl Citrate, Polysorbate 80, and Sodium Citrate.

How do I know if CholestOff is right for me?

Choosing the right product is the #1 question asked by DietSpotlight readers. We recommend trying any product before buying it and know that finding a product with a sample offer is near impossible - so we created our own product, Burn HD, with scientifically backed ingredients.

Click here to get your sample of our powerful fat burner today.

Does CholestOff work?

There are no ingredients in CholestOff that work to increase weight-loss.

How much does CholestOff cost?

For a one-time purchase, you can buy it for about $13.00.

How should I take CholestOff?

You should take two capsules two times a day.

Can I take CholestOff if I have a health condition?

You should ask your physician if you have health problems, are under the age of 18, pregnant, nursing, or are taking prescriptions.

What company is behind CholestOff?

Nature Made is the company behind CholestOff.

Does CholestOff contain yeast?

No, CholestOff doesn’t contain yeast, starch, preservatives, synthetic dyes, or gluten.

Do you know of any special deals or discounts on CholestOff?

There are deals and discounts, if you subscribe to get CholestOff once every one to six months; you can save between 5% and 15%.

If you’re looking to lose weight, you may want to look at Dietspotlight Burn’s special trial offer. Users are going crazy over the deal because it’s only the cost of shipping and handling. Click here to check it out!

What is CholestOff plus?

Good heart health requires healthy cholesterol levels. CholestOff® Plus is formulated with Reducol. This is a proprietary formula of plant stanols and sterols. These reduce the absorption and release of dietary cholesterol into the bloodstream and have been shown to lower LDL (“bad”) cholesterol.

What is Cholestoff used for?

A dietary formula containing the proprietary phytosterol blends Reducol™ and Pantesin, Nature Made CholestOff® Complete works to lower LDL cholesterol. The plant sterols and stanols inhibit the absorption of cholesterol consumed through the diet.

CholestOff Ingredients

CholestOff Ingredients and Supplement Facts

Serving Size: 3 softgels
Serving Per Container: 120
Amount per Serving% DV
Plant sterols / stanols900 mg*
Pantethine300 mg*

Other Ingredients: None

We dug deep into the Cholestoff ingredients to give you the details you need.

Plant Sterols

Plant sterols are naturally occurring substances found in seeds, grains, nuts, legumes, fruits, and vegetables. They are also sometimes added to other foods.

What is it Supposed to Do?

Plant sterols are known for their ability to help lower cholesterol.

Clinical Research

According to a study published in Atherosclerosis, “it has potential value as an adjunct to dietary therapy in patients with mild hypercholesterolemia for whom long-term drug therapy is deemed advisable.”

Clinical research is an important part of the equation when it comes to choosing a diet supplement. You may want to take a look at a product like Dietspotlight Burn, which is formulated with clinically tested ingredients.


These are naturally occurring substances similar to plant sterols.

What is it Supposed to Do?

They are known for their cholesterol lowering abilities.

Clinical Research

According to a study published in Mayo Clinic Proceedings, “Present evidence is sufficient to promote use of sterols and stanols for lowering LDL cholesterol levels in persons at increased risk for coronary heart disease.”


Calcium is the most abundant mineral in the body. It is found in a variety of food sources including dairy products and leafy green vegetables. It is also added to some foods and is available in supplement form. There are a number of calcium supplements available, such as calcium citrate, and calcium with vitamin D.

What is it Supposed to Do?

Most of it goes to the bones and teeth for structure and support, but the remaining small percentage stays in the blood and muscle tissue.

Clinical Research

According to a study published in Atherosclerosis, “There was no significant difference in the cholesterol levels in the yoghurt and calcium groups.” We found no connection with weight-loss.

Magnesium Stearate

This is a “flow agent” added to many dietary supplements. It doesn’t do anything to help the body in any way.

What is it Supposed to Do?

It is supposed to keep ingredients from sticking together during mixing and compression. It adds no nutritional value to the supplement.

Titanium Dioxide

A chemical most often found in sunscreens. In other products it’s there to maintain color.

What is it Supposed to Do?

It is used as a colorant, and adds no nutritional value to the supplement.

Silicon Dioxide

It is a chemical, also known as silica.

What is it Supposed to Do?

It is an anti-caking agent, designed to keep the ingredients from sticking together during production. It adds no nutritional value to the supplement.

Is There Anything Out There That TRULY Works?

We have our eye on a supplement that fits the bill. Dietspotlight Burn, which is formulated with ingredients that HAVE been clinically tested, may be a good option. All customers can take advantage of a special trial offer, currently available. Click here to give it a try.


Previous CholestOff Review (Updated September 20, 2014):

What You Should Know About CholestOff

Cholestoff, manufactured by Nature Made, is a product that claims to naturally help to lower the cholesterol for those that high levels of it. This product is said to contain ingredients that have been well known to lower the cholesterol naturally in the body and these ingredients reportedly prevent the body from absorbing any further dietary cholesterol.

According the statements on the Cholestoff site, the natural supplement can help to reduce the cholesterol by up to 24% and also reportedly helps to improve the overall health of the heart as well.

List of ingredients in CholestOff

Cholestoff contains quite a range of ingredients and among these are: plant sterols or stanols from pine trees, Tribasic Calcium Phosphate, Croscarmellose Sodium, Hydroxypropyl Methylcellulose, Calcium Carbonate, Silicon Dioxide, Magnesium Stearate, Titanium Dioxide (artificial color), Polyethylene Glycol, Triethyl Citrate, Polysorbate 80 and Sodium Citrate.

Product Features

First of all, when looking at Cholestoff you should be made aware that the bottom of the site clearly states that the product is not meant to cure, treat, diagnose or prevent any disease which makes the viewer wonder if the product matches the hype that has been attached to it. Secondly, it also mentions that it has not in any way been evaluated by the Food and Drug Administration (FDA) which again leads to scepticism about the product.

Cholestoff is not suitable for pregnant women or women who are breastfeeding and also, despite the fact that it is a supplement, the user should consult with a medical professional such as their local doctor or physician before taking the product.

Advantages of CholestOff

  • Cholestoff uses plant derivatives as its active ingredients which are all natural.
  • Cholestoff is very inexpensive. One bottle of Cholestoff retails for about $7.

Disadvantages of CholestOff

  • Cholestoff makes a lot of claims on the official website but has limited information backing them up.
  • For those with high cholesterol, you may want to rely on products a little more well known to avoid serious health issues.
  • Various reviews around the Internet vary greatly between "Doesn't work" and "Wonderful" so we can't get a good feel for the effectiveness of this product.
  • Cholestoff is ineffective as a weight loss supplement.


High cholesterol can lead to life-threatening conditions if left untreated for a long period of time. Cholestoff claims to help lower your cholesterol which could be very beneficial. This product is so inexpensive, we don't see how it could hurt to add it to your daily routine if you are concerned about your cholesterol levels but you may want to use it in addition to something recommended by your physician. We can't really categorize Cholestoff as a "weight loss" product so if you are looking for a way to lose weight, you should probably keep looking.

Summer Banks Dietspotlight Author
About the Author:

Summer Banks, Director of Content at Dietspotlight, has researched over 5000 weight-loss programs, pills, shakes and diet plans. Previously, she managed 15 supplement brands, worked with doctors specializing in weight loss and completed coursework in nutrition at Stanford University. full bio.

69 CholestOff Reviews

  • Is this safe with other medications?
    Jose Gonzalez

    I take Crestor and Metformin. Is CholestOff Plus safe to use with these medications?

    • Your Name

      It is safe to use with statins buf double check with your doctor first.Tell us your thoughts about Cholestoff.

    • Maribel (Editor)

      Hi Jose! Because of possible interactions with medications, please make sure to consult with your physician before taking this product.

  • 2754


    • Johna

      Can I take Cholestoff with Zetia(not a statin, but and alternative prescription) I can’t take statins as they caused side effects.

    • Isabel

      Yes you can take Cholestoff with high blood pressure meds.

    • Maribel (Editor)

      Hi Gladys! Because of possible interactions with medications, please make sure to consult with your physician before taking this product.

  • How soon does Cholestoff starts working?

    How soon does Cholestoff starts working?

    • Your Name

      I had a particle lipid test done. My cholesterol went from 2832 to 2547 in 6 weeks. A little over a year it went down to 1450.

    • Maribel (Editor)

      Hello Nelly. After some research, we discovered that, there are no ingredients in CholestOff that work to increase weight-loss or improve metabolism.There are other products out there that do, however. Might want to explore Dietspotlight Burn. Hope this helps.

  • What are the adverse side effects?
    Mary Puraty

    What are the adverse side

    • Maribel (Editor)

      Hello Mary. All users are different and can experience different side effects; please make sure to consult with your physician before taking this product.

  • Can take with BP meds?

    I take blood pressure medicine, is it okay to take cholestoff?

    • Maribel (Editor)

      Hi Alice! Because of possible interactions with medications, please make sure to consult with your physician before taking this product.

  • Will it help to lower cholesterol

    my cholesterol is a little high if i start taking cholestoff vitaman do you think it will help lower it

    • Your Name


    • Maribel (Editor)

      Hi Caralyn! Please make sure to consult with your physician before starting a new weight-loss program or product.

  • Linda

    Will it work if your body makes cholesterol? I want to lower it naturally. Just bought some to try.

    • Candace (Editor)

      All human bodies produce cholesterol. If you mean an excess of bad cholesterol then you should take this product to your doctor to see if this can help you. Losing weight, also helps lower your cholesterol. A product known to help with excess weight is Dietspotlight Burn. It has worked for many, and could work for you too. Best of luck!

  • a b

    I’ve taken Cholestoff for nearly six months months – also lowered use of mayonnaise, cheese, red meats, etc. Cholesterol went down from 253 to 197. Weight also went down from 171 to 149. No apparent side-effects.

  •  Cholestoff
    LA (Verified User)

    Cholestoff worked for me. Lowered by cholesterol by 30 points, did not need to lose any weight although I did. Just one question does this cause a darker stool?

  • sandy

    I have been taking cholestoff plus for a year now. I just had blood done, I went from 229 to 236….what the heck!! I also had heart papatations. I stopped taking it and so far no palpatations..

    • Jeremy

      Similar situation for me cholesterol-wise…Cholestoff sucks

  • PattiLee

    Can I take CholestOff if I am allergic to pine trees?

  • Lori

    I only recently began taking Cholestoff due to first time lab results with high bad cholesterol level. I’m glad it doesn’t cause weight loss as its not a weight loss product. I am a female in my upper 50’s, thin (125 lbs) and always have low blood pressure. Due to past accident, I’ve had neck surgery due to 3 bulging discs so have developed pain and arthritis which is chronic. I have not noticed any side effects (yet)–only started about a month ago–but normally side effects show up pretty quickly if there are any. My only concern is that I read this product can interfere with vitamin absorption, such as Vit. D, E and a couple others. This should be more publicized with the product so that people can adjust when to take any vitamin supplements (in between Cholestoff ingestion times). I won’t know how effective this product is until another 5 months or so when I plan to have another blood test

  • Penny

    I just started taking the original not sure which one since there are two others cholestoff. My Total is out of site 435 can’t take statens any more cant take Zetia or Gemfiberozil so doctor didn’t know what else to put me on my daughter takes this so I thought I would try it hope I got the right kind I’ll find out

  • SueGYour Name

    Has anyone experienced muscle and joint stiffness while using this product ? It has worked in lowering my cholesterol , but the stiffness is very bothersome.

    • Lisa M.

      SueG, I have been taking the Cholestoff extra strength for a year now, and just recently experienced the same effects you stated. I’ve been fine, and now I had to stop because of the muscle cramping and aching joints. I can’t take Lipitor because the pain and cramping in my lower body was terrible.

    • Martin Andrews

      I’m having the same problem went from walking 31/2 miles to none because my joints and muscle hurt so much stopping taking it will let you know

    dotty b (Verified User)


    • Your Name

      Thank you.

  • CholestOff
    Your Name (Verified User)

    Just had my annual physical. Dr had wanted to put me on stating to reduce cholesterol levels. I refused because of their side effects. I started taking Cholestoff at the beginning of the year along with a healthier diet and she said my levels are down substantially, she no longer wants me to take stating and told me to keep up whatever I’m doing. NO WHERE have I seen Cholestoff claim to be a weight loss supplement. Weight loss shouldn’t be sought through magic pills but rather through a healthier lifestyle…cholesterol control is different.

  •  Product really works
    Latonya (Verified User)

    My particle cholesterol level went from 2847 to 2532 in 6 weeks. A little over a year it was 1450. My calculated cholesterol went from over 200 to 145. Those are two types of cholesterol tests. The particle is more accurate. Cholestoff works! The biggest diet change I made was decreasing my ice cream intake.

  •  Product works for me
    Latonya (Verified User)

    I took this product for a little over a year. My cholesterol went from 2832 to 1450. This is from a particle lipid test, not calculated. Most people have the calculated test, whereas your number should be below 200. A particle test is more accurate. You can have a normal calculated test, but particle shows the truth. Cholestoff works!

  •  It's not cheap
    Matt (Verified User)

    It’s not cheap

    • Edward Bond

      U are soooo correct

    • Dustin

      Yes it’s not but is it worth it for a healthier life? I do believe it is probably better and safer for you.

  • Does Cholestoff contain anything that could be bad for the heart?
    Roberta (Verified User)

    I have been taking Cholestoff for several weeks, and I developed heart palpitations during this time. Not sure if they’re connected. Has anyone else had this experience? Does Cholestoff contain anything that could be bad for the heart?

    • judy

      I been taking Cholestoff for nearly a month and until i read that you were having palpations i couldnt figure out why my heart was beating differently almost like its racing i will stop taking cholestoff. Did your palpations stop after discontinuing it.

      • Linda

        I went online today to look up the side effects of Cholestoff because I have been taking it for about a month and have developed unusual heart palpitations.I will stop taking it and hopefully the will go away.

      • SherryR

        I have been taking it for approx 6 weeks. I am having odd heart rhythms or palpitations too…that’s why I am on this site! I wonder if 2 tablets twice a day is too much for me? I am a small person (5’1″ and 100 lbs) It doesn’t make sense that the dosage would be the same for someone my size and also a large male…? Thoughts?
        I am hopeful this will lower my LDL because I refuse to go on Statins!!

    • Randy

      I have had heart palpitations for over 40 years. I take magnesium (American diets very deficient in Mg which you get from green leafy vegetables like kale) for my palpitations. I notice that it helps a lot. I take 400 mgs at night – very soothing to the system. Dr. Carolyn Dean, M.D., N.D.(also a naturopath) wrote a book – The Magnesium Miracle – about magnesium. You may want to look into this and see if it is helpful for you.

  • Does cholestoff turn your stool dark?

    Does cholestoff turn your stool dark?

  •  Hope this works for me
    Anonymous (Verified User)

    I just start taking CHOLESTOFF… hope it works for me… after taking Crestor for a long time I start having terrible muscles pain. I’ll post again in a couple of month and see if it owrks for me

  • debbie levesque

    i’m on 40mg of zocor, can i take cholest off with that.

  •  Product absolutely works!
    Catherine (Verified User)

    I t works. In 6 months went from 220 to 181.

  •  Product really works and lost weight
    jerry (Verified User)

    I would like to say this stuff really works!!! I dropped from a 163 to a 130 in 2 weeks, I promise!! I really believe I will be at good levels within 2 months

  •  CholestOff
    DIANE (Verified User)

    My moms cholesterol level went down 24 points on this, but while taking this with Red Rice Yeast she got really really ill and had to stop the Red rice yeast. I am taking Cholest off and have lost a few pounds already!

    • Mary

      ive been taking cholest off for appx 6 weeks due to high total cholesterol. Happened to also lose a stubborn 6-7 pounds since starting. I’m sure weight loss is directly related to the pills. Haven’t had follow up blood work yet. Dr. wants to test in 6 months.

  •  I have used Cholestoff w/ Red Yeast Rice for several years. My cholestrol level continues to come down. I have avoided taking prescription medication. High cholestorl runs in my family and I have wanted to avoid taking it. I am also a runner [I run every day] and a vegetarian!
    Colleen (Verified User)

    I have used Cholestoff w/ Red Yeast Rice for several years. My cholestrol level continues to come down. I have avoided taking prescription medication. High cholestorl runs in my family and I have wanted to avoid taking it. I am also a runner [I run every day] and a vegetarian!

  • Has anyone else had digestive issues along with Cholestoff?
    Sheri (Verified User)

    I’ve had really good luck with Cholestoff lowering my cholesterol numbers, but I’m having a lot of bloating, gas, and loose stools. Lots of stress in life right now, so I’m not sure what is the culprit, but started taking Cholestoff about the time the stress began. Has anyone else had digestive issues along with Cholestoff?

    • Larry

      I had the same bloating thing at first, but it seems to have gone away. Maybe because I now make sure I take it before a meal (or just after).

    • Linda

      I have been on it for about 4 months. I do suffer from digestive issues, mostly due to taking a lot of supplements. However, since taking Cholestoff Complete, I have had consistently very loose stools. I plan to go off it when I finish the last bottle. Also, I have been under recent stress and my blood pressure has gone up dramatically. Had to change blood pressure medications. I will go for blood work this week to see if the Cholestoff even reduced my cholesterol. I didn’t feel well recently and stopped all supplements including Cholestoff, and the diarrhea stopped.

  • can I take cholestoff instead of zocor?

    Zocor has given me diabetes
    can I take cholestoff instead of zocor?

    • tony

      zocor has given you diabetes???? are you positive???maybe I should stop taking zocor!!!

      • Anonymous

        alot of the prescription statins cause your blood sugars to go way up. Same thing happened to me, was put on meds for diabetes and test every day with my meter. Went of statins and guess what diabetes went away and metformin discontinued!!!!!! It is not an uncommon complication of statin drugs. I am going to try cholestoff instead….

  •  I decided to continue taking it.
    medy (Verified User)

    As a nurse I was very skeptical to take supplements and statin. I came across Cholesteroloff at Costco and read the ingresients. I asked my doctor about it and we both decided to check my cholesterol level as the baseline reading.However, I was still skeptical and waited another month.Then I decided to take Cholesteroloff for 4-6 weeks and had my cholesterol level checked and to my surprise my cholesterol dropped to 193.I decided to continue taking it but will have frequent chemistry testing of my kidneys, liver and cholesterol or lipid profile.Furthermore,hyperlipidimia runs in my family.

    • medy's arch nemesis

      193 from what? Think before posting people. Unless you give numbers to compare to, this new number is absolutely useless information. You must have made such a reckless nurse.

      • RBW.

        Take a chill pill and an antihistamine for your snot nose

        • Monique

          I’m going to try it. I shall let you know the outcome..

  •  Cholestoff really worked for me!
    Stephanie (Verified User)

    I have been taking Cholestoff for months..after having horrible side effects from prescription statin meds. which did not work well. Cholestoff really worked for me! My doctor was so pleased with my blood test results and then I told her that I had been taking Cholestoff for the previous 6 months. (she had never heard of it!)

  •  I used cholest off for 4 months without side effects
    Steve (Verified User)

    I take losartan and metoprolol er and have used cholest off for 4 months without side effects. I also started a low fat low cholesterol diet at the same time. My blood test showed a drop in total chol. from 235 to 193. If you’re interested in this product you can buy 240 caplets at amazon.com fo about $15 (about a 2 month supply) There are other supplements that are supposed to be much better, but they run about $35-$40 per month. With the cost so low, it’s at least worth a try.

  • Asking for diet chart.

    can you take cholet off & fish oil together

    • Anonymous

      Yes you can my dr recommended me taking the two together

  •  Going to start it.

    With no diet modification my cholesterol has remained as with meds. I’m going to change my diet to try and reduce it further. At least I have no muscle pain w/ Cholestoff. Muscle pain is a major side effect of Simvastatin.

  • gladys

    can i take this my blood presure meds

    • rosie montoya

      Can we take highblood presure medication

  • I would like to see scientific studies on Cholestoff.
    Dennis Jones

    I would like to see scientific studies on Cholestoff. Otherwise, I do not take your commendable comments of Cholestoff seriously.

    • Dustin

      There have been studies and everything in these comments are what is found in these studies. It is suggested to consult a doctor before taking any pill like this because it can cause issues like blood sugar rising and constipation ect. If you have any of the symptoms that this might cause your doctor might advise against it. Now unless you have high blood sugar or close to borderline trying this product could be an issue. I seriously suggest consulting a doctor before taking this.