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CholestOff Review - 9 Things You Need to Know

CholestOff by Nature Made is a dietary supplement that claims to “lower blood cholesterol levels.” According to the company behind it, CholestOff “contains active ingredients that block your body’s absorption of cholesterol while improving your cardiovascular health.” CholestOff is neither a remedy for someone with a medical condition nor a weight loss pill – it is merely a preventative supplement.

We wanted our research team to investigate the use of CholestOff in clinical studies to see if it has long-term benefits. So, we looked into the science behind to product to give you the Bottom Line. Read on to learn what we found.

CholestOff can be purchased through their Official Site.

CholestOff Readers: Noom is offering our readers a risk-free trial, for a limited time. Click here for more information!

What is CholestOff?

CholestOff is a nonprescriptive, dietary supplement that claims to “lower the levels of blood cholesterol.” The supplement is also widely prescribed as an enhancement for cardiovascular health and wellbeing.

Cholest-Off is a California-based manufacturer of dietary supplements, multivitamins, and herbal supplements, Nature Made or Pharmavite, LLC.

According to Nature Made, CholestOff uses a proprietary blend of plant stanols and sterols called Reducol, a tasteless, odorless ingredient that they state “works as a catalyst that blocks the absorption of cholesterol in the gut.”

Reducol is also a popular ingredient in the manufacture of dietary supplements and fatty and nonfat functional foods. The naturally occurring plant sterols and stanols are present in leaves, vegetables, and nuts of various plants.

Through decades of research, plant sterols and stanols have been useful as a critical ingredient in supplements and drugs.

One serving of CholestOff supplies 0.9g of sterols and stanols in capsule form. Users of CholestOff should consult their physicians as part of the cholesterol management program.

A complete regimen encompasses regular checks of cholesterol levels, a healthy diet, physical exercise, and bodyweight management.

What does the research have to say about the Reducol component?

  • Journal of Agricultural and Food Chemistry – “Phytostanyl fatty acid esters, which are being added to a variety of foods owing to their cholesterol-lowering properties, are susceptible to thermally induced oxidation reactions.” Such fatty acid esters are found in ingredients like Reducol.
  • Clinical Journal of Nutrition and Dietetics – You can even add Reducol to plant-sterol enriched milk for positive results on cholesterol levels.
  • Journal of Oleo Science – A direct look into plant sterols in other research again shows a promising impact on cholesterol.

What is Cholesterol?

To learn and appreciate the benefits of CholestOff, it is crucial to understand what cholesterol is.

Blood cholesterol is crucial for making hormones and digesting food. However, having too much cholesterol can have effects on your health

According to Nature Made, “CholestOff lowers the level of LDL and Non-LDL cholesterol.” Though Nutrients also notes their potential benefits, larger and more comprehensive studies are needed to confirm these findings.

The National Institutes of Health (NIH) advises people who want to manage their cholesterol levels to decrease their dietary intake of saturated fats, trans fat, and cholesterol.

Sterols Vs. Stanols

Sterols and stanols sound an awful lot alike; there are similarities and differences. On a molecular level, both look similar to cholesterol. You can find both in foods, but some companies understand sterols and stanols benefit health, according to the Journal of AOAC International.


CholestOff Ingredients

The active ingredients in CholestOff, are sourced from natural plants such as the pine tree.

The foods with high concentrations of fortified stanols and sterols include granola bars, yogurt, margarine, and orange juice.

Regarding this dietary supplement, four caplets of CholestOff can deliver up to 1.8g of sterols and stanols.

According to the instructions, CholestOff contains no artificial flavors, gluten, preservatives, or yeast. Besides plant sterols and stanols, other ingredients include:

  • Plant Sterols/ Stanols (Pine Tree)
  • Cellulose Gel
  • Polyethylene Glycol
  • Calcium Carbonate
  • Triethyl Citrate
  • Polysorbate 80
  • Tribasic Calcium Phosphate
  • Silicon Dioxide
  • Hydroxypropyl Methylcellulose
  • Croscarmellose Sodium
  • Magnesium Stearate

Hydroxypropyl Methylcellulose is a coating agent many pharmaceutical companies use. While Croscarmellose sodium and Polysorbate 80 works as an emulsifier.

Magnesium stearate is a standard white substance used in the manufacture of some diet pills.

Silicon dioxide helps absorb moisture and is considered an anticaking agent.

Polythene glycol is a popular polyether compound in several medications, while Triethyl citrate is a colorless and odorless liquid that helps stabilize foams. The ingredient is also used by pharmaceutical companies for coating purposes.

Supplements such as CholestOff should not be taken to treat health issues. For this reason, patients are advised to consult the doctor before taking any dietary supplements.

Does CholestOff Work?

Does CholestOff Work?

Some research supports the effectiveness of CholestOff in their claims of reducing the blood cholesterol levels. According to the International Journal of Food Sciences and Nutrition, supplementation with a dietary supplement containing plant sterols/stanols reduced the total cholesterol by 2.8%, LDL cholesterol by 4.9%, and non-HDL cholesterol 3.6%.

Most of the reviews concerning CholestOff on sites like Amazon.com are positive.

Sterols are widely available in natural foods such as grains, vegetables, and fruits.

Side Effects

CholestOff Side Effects

There’s no mention of side effects from CholestOff. However, taking CholestOff products are not recommended for children, pregnant or lactating mothers. Restrictions also apply to people with certain medical conditions and those allergic to pine trees and constituent products.


CholestOff Directions

The recommended serving of CholestOff for high cholesterol and other natural support is two capsules, two times a day, which equals a 1,800 mg dosage. The CholestOff Original contains 60 to 120 caplets, depending on the container size.

The supplement is best before meals; Nature Made recommends taking between 15 to 30 minutes before mealtime.

To better swallow the pills, you can drink water before and during consumption.

Where To Buy

Where to Buy CholestOff?

Although you can’t buy the supplement on the official website, online retailers that offer the supplement include Walgreens, iHerb, and Jet.

There is also a location finder on the official website if you would like to purchase the supplement at a store near you.

CholestOff prices range heavily based on where you buy it. For example, a 60 count bottle costs about $10.61 on iHerb.

What Users Are Saying

What Users Are Saying

“I just have had blood work to check my cholesterol levels and they have really improved since I started using this product!”

“Did not work at all – I bought these hoping to avoid an Rx. My cholesterol went up one point after a month, they did nothing. Also my one LIVER ENZYME was elevated (one other reviewer claimed elevated liver enzyme) I will be throwing the rest of the bottle out. While I was taking them, i chewed them because they were big. I doubt if this had an effect because they are not enteric. Waste of money.”

“Makes u a bit nauseas but so far so good. Have to take with food. But I’m happy with the price and all 30 were in.”

Bottom Line

The Bottom Line on CholestOff

While many supplements marketed for their ability to lower levels of cholesterol show promise, a few others are neither strong nor effective in lowering the levels of cholesterol.

The results obtained from people using CholestOff can vary, depending on whether the individual has a history of heart conditions, preexistence medical condition, nursing or pregnant.

Before taking CholestOff for weight loss, it is important to understand that there are diet pills, supplements and support programs on the market that are more effective for weight loss.

If you’re looking to improve overall health and increase weight-loss, we suggest going with a program that provides more bang for your buck and scientific evidence that proves it works.

Among the best products we’ve seen this year is one called Noom. The clinically-tested program works to help you lose weight and keep it off. It’s likely the unique approach to weight loss that makes the program successful. You get personalized meal plans, human coaching and much more that you don’t find in other apps.

Also, the makers of Noom are offering customers a free trial offer, which is a sign of confidence in their product.

Learn More About Noom »
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What are the side effects of CholestOff?

CholestOff side effects could include bloating, indigestion, gas, and stomach pain.

What are the ingredients in CholestOff?

CholestOff ingredients are Plant Sterols/Stanols (Pine Tree), Calcium Carbonate, Tribasic Calcium Phosphate, Croscarmellose Sodium, Hydroxypropyl Methylcellulose, Silicon Dioxide, Magnesium Stearate, Color Added, Polyethylene Glycol, Triethyl Citrate, Polysorbate 80, and Sodium Citrate.

Does CholestOff work?

There are no ingredients in CholestOff that work to increase weight-loss.

How much does CholestOff cost?

For a one-time purchase, you can buy it for about $13.00.

How should I take CholestOff?

You should take two capsules two times a day.

Where can I buy CholestOff?

CholestOff can be purchased using their Official Site.

Can I take CholestOff if I have a health condition?

You should ask your physician if you have health problems, are under the age of 18, pregnant, nursing, or are taking prescriptions.

What company is behind CholestOff?

Nature Made is the company behind CholestOff.

Does CholestOff contain yeast?

No, CholestOff doesn’t contain yeast, starch, preservatives, synthetic dyes, or gluten.

Do you know of any special deals or discounts on CholestOff?

There are deals and discounts, if you subscribe to get CholestOff once every one to six months; you can save between 5% and 15%.

If you’re looking to lose weight, you may want to look at Dietspotlight Burn’s special trial offer. Users are going crazy over the deal because it’s only the cost of shipping and handling. Click here to check it out!

What is CholestOff plus?

Good heart health requires healthy cholesterol levels. CholestOff® Plus is formulated with Reducol. This is a proprietary formula of plant stanols and sterols. These reduce the absorption and release of dietary cholesterol into the bloodstream and have been shown to lower LDL (“bad”) cholesterol.

What is Cholestoff used for?

A dietary formula containing the proprietary phytosterol blends Reducol™ and Pantesin, Nature Made CholestOff® Complete works to lower LDL cholesterol. The plant sterols and stanols inhibit the absorption of cholesterol consumed through the diet.

94 CholestOff Reviews

  • Asking for diet chart.

    can you take cholet off & fish oil together

    • Anonymous

      Yes you can my dr recommended me taking the two together

      • Terry

        You should also take K2 and D3 supplements with CholestOff. K2 is critical for cardiovascular health, and statins deplete it. Take CholestOff with a meal to avoid stomach issues.

  • Going to start it.

    With no diet modification my cholesterol has remained as with meds. I’m going to change my diet to try and reduce it further. At least I have no muscle pain w/ Cholestoff. Muscle pain is a major side effect of Simvastatin.

  • gladys

    can i take this my blood presure meds

    • rosie montoya

      Can we take highblood presure medication

  • I would like to see scientific studies on Cholestoff.
    Dennis Jones

    I would like to see scientific studies on Cholestoff. Otherwise, I do not take your commendable comments of Cholestoff seriously.

    • Dustin

      There have been studies and everything in these comments are what is found in these studies. It is suggested to consult a doctor before taking any pill like this because it can cause issues like blood sugar rising and constipation ect. If you have any of the symptoms that this might cause your doctor might advise against it. Now unless you have high blood sugar or close to borderline trying this product could be an issue. I seriously suggest consulting a doctor before taking this.

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