Updated: 04/18/2017 - Site operated by Leptigen
By Summer Banks Mar 27, 2017

I’m here to cut through the noise and get you to the bottom line on Diurex. Our in-depth review examined the ingredients, side effects, and scientific studies. Additionally, we picked apart hundreds of user comments. Then, we condensed and summarized to give you with the info you need.

Diurex Readers: Click here to find out why we're giving away samples of our product, Leptigen.

What is Diurex?

First off, Diurex is an over-the-counter diuretic. The ingredients are Magnesium Salicylate (NSAID), and caffeine anhydrous. [1] [2] There are other products under the brand, including, Aquagels, MAX Water Caplets, Ultra, Water Pills, WaterCaps and Water Capsules. These are intended to “temporarily” reduce bloating and excess water weight. Typically, you’ll take one or two capsules per day.

Alva-Amco Pharmacal, a company dating back to 1904, makes Diurex. Local drugstores and online retailers sell the supplement. We like that is contains a few natural ingredients and that we found some positive customer comments, but read on…

Diurex Side Effects – “Positive or Negative?”

The first issue centered on Diurex ingredients. “Whenever you choose a new supplement you need to take into consideration how it will make you feel,” said our Research Editor. “In this case, users have reported some adverse reactions.”

One customer commented, “Diurex causes diarrhea.”

“Just makes me nauseous,” said another user.

Although some users experienced side effects, we found that others didn’t.

“Gave me a slight headache, but it went away when I drank a couple glasses of water,” stated a customer.

Limited Results – “Any Weight Loss?”

According to Diurex reviews, some users didn’t see and solid results. One customer revealed, “Didn’t lose a single pound. These just make you pee a lot.”

Another user said, “No weight-loss from this.”

While there are comments about not seeing any changes, there are the occasional review of Diurex talking about seeing positive results.

“Took it for a few days and my jeans fit better than before,” said a user.

“Dropped a couple of pounds,” reported another.

According to our research, long-term success is limited when a supplement doesn’t produce solid results. There’s a bigger issue if dieters use Diurex and don’t notice any changes.

The Science – “Is There Clinical Support?”

There’s no clinical research presented on the official website about Diurex water pills. However, this product does contain solubolized pamabrom; which acts as a diuretic and may help remove excess water weight from the body. The chances of long-term weight-loss are slim, considering it doesn’t contains fat burners or metabolism boosters. Science-based facts are critical to us at DietSpotlight. There are concerns when it’s missing.

The Bottom Line – Does Diurex Work?

Hold up just one more minute, here are our final thoughts on Diurex water pills. We like that the ingredients are natural and it may help with water retention. But, we’re concerned about the lack of research connecting this one to weight-loss. There’s also an issue with customer reviews talking about negative side effects.

If you need to see faster fat loss results and a slimmer figure, we encourage you to choose a diet supplement packed with clinically-tested ingredients, not connected to harmful side effects and supported by positive user feedback.

Among the best products we’ve seen in 2017 is one called Leptigen. This weight-loss pill contains four clinically-tested ingredients that have been shown to help boost metabolism and increase fat loss. There’s no chatter about harmful side effects and user feedback mentions people are seeing great results.

Also, the company that makes Leptigen is so confident in the formula they’re offering a Special Trial Offer, which is quite a good sign.

Previous Diurex Review (Updated July 9, 2014):

What You Should Know about Diurex

Diurex is a dietary supplement that is manufactured by Alva-Amco Pharmacal Companies, Inc., a company founded in 1904. It is marketed towards both women and men. This product aims to assist with discomforts by reducing "excess body water." There are actually five separate versions of Diurex for women; Diurex Aquagels, Diurex Water Capsules, Diurex Water Caplets, Diurex PMS and Diurex Water Pills. There do not appear to be any customer testimonials for this product. Diurex supplements can be purchased in most common drugstores and grocery stores.

The active ingredient found in Diurex supplements is Solubilized Pamabrom (diuretic that is stated to assist with bloating). Diurex endeavors to aid women with monthly swelling, bloating, water weight gain and puffiness due to their menstrual cycle. These diet supplements are stated to be free of aspirin and caffeine. Unfortunately there are no free trial samples of Diurex products available through the official website. Diurex is available without a prescription, but doesn't appear to be offered with a 100% money-back/satisfaction guarantee. There is no diet plan or fitness regimen recommended with Diurex supplements. The version of Diurex for men also aims to help minimize unwanted water weight. There doesn't appear to be any actual clinical research provided on the official website. This product sells for $25.74 for a 60 count of pills.

List of Diurex Ingredients

Solubilized Pamabrom, FD&C Blue #1, Gelatin, Glycerin, Hypromellose, Polyethylene Glycol, Povidone, Propylene Glycol, Purified Water, Sorbitol and Titanium Dioxide.

Product Features

Diurex is a dietary supplement that is claimed to assist women and men with water weight reduction and bloating. This product comes in five different forms and is directed to be taken with water after breakfast. The primary active component incorporated into Diurex is Solubilized Pamabrom, a diuretic that is stated to assist with bloating. This weight reduction supplement can be acquired in most typical grocery stores and drugstores. There is no clinical data offered on the website for Diurex supplements. Diurex sells for $25.74 and is available without a prescription.

Advantages of Diurex

  • Diurex can be easily and conveniently purchased in most common drug and grocery stores.
  • Diurex is available to both men and women.
  • A full ingredient list is offered on the official website for Diurex supplements.

Disadvantages of Diurex

  • There are no customer testimonials for Diurex offered on the official website.
  • Some ingredients found in Diurex supplements may not be suitable for some individuals. (See Diurex Side Effects).
  • Diurex does not actually sell conveniently through the official website.
  • Using a diuretic to achieve significant weight loss can be unhealthy, and any weight loss users do see will likely not last very long.
  • Diurex supplements are not offered with a 100% money-back guarantee.
  • There are no free trial samples of Diurex products available through the official website at this time.

Conclusion on Diurex

Diurex is pitched rather differently than most weight reduction supplements. This product doesn't endeavor to suppress the user's appetite, burn calories, boost energy levels, assist the metabolism or burn away unwanted fat. Diurex mainly addresses water weight gain and the menstrual cycle of women. Therefore it's probably wise to investigate a number of other diet drugs before selecting a diuretic such as Diurex. In the end, it would be more reassuring to see some clinical data posted on the official website, along with some customer testimonials for Diurex and a 100% money-back guarantee.

Diurex Questions & Answers:

We picked apart hundreds of user comments about Diurex into this helpful FAQ.

What are the side effects of Diur?

Some Diur short for Diurex, side effects may include frequent urination, increased heartrate and blood pressure, sleeplessness, irritability and nervousness.

What are the ingredients in Diurex?

Diurex ingredients are caffeine, magnesium salicylate, pamabrom, calcium carbonate, calcium sulfate, cornstarch, d&c yellow no. 10 lake, ethyl vanillin, fd&c blue no. 1 lake, fd&c blue no. 2 lake, hypromellose, magnesium silicate, magnesium stearate, mineral oil, polyethylene glycol, sodium lauryl sulfate, stearic acid and titanium dioxide.

Does Diur work?

There’s no solid science linking the ingredients in Diurex to weight-loss. We found studies supporting the effectiveness of caffeine, but nothing that is just about this supplement. You may want to think about changing out Diurex with a supplement like Leptigen, which contains ingredients that have been clinically tested.

How much does Diurex cost?

Diurex costs $7.56. Considering the supplement is available through various retailers, the price could change.

How should I take Diur?

You should take three to four Diurex capsules while symptoms persist. The company suggests not taking more than four pills in one day.

Can I take Diurex if I have a health condition?

Women who are pregnant or nursing, those taking prescription medications of any kind, people with health conditions or anyone under 18 years of age should contact a healthcare professional prior to using any dietary supplement, including Diurex.

What do users like about Diur?

Some users liked that Diurex was easy to take and available through multiple retailers.

What do users NOT like about Diurex?

We found that some users didn’t like the side effects of Diurex and that the supplement didn’t help with weight-loss.

How do I contact the Diur customer service department?

You can contact the Diurex customer service department by calling a representative at 1-800-792-2582, mailing letters to Alva-Amco Pharmacal Co. Inc. 7711 Merrimac Ave. Niles, IL 60714-3423 or by emailing customer_service@alva-amco.com.

What is the active ingredient in Diurex?

The active ingredient in Diurex is caffeine.

How long can I use Diurex?

You can use Diur continuously for 10 days.

Can men use Diurex?

Yes, men can use Diurex. As a precaution, you should consult with a healthcare provider prior to using weight-loss supplements.

Does Diurex come with a guarantee?

There’s no mention of a guarantee with Diurex, likely because it is not sold by the manufacturer. You will need to visit the retailers selling the product for details about the return policy.

Do you know of any special deals or discounts on Diurex?

We didn’t find any special deals or discounts on the Diurex official website. However, the last few months have been buzzing, considering our readers have been taking advantage of Leptigen’s Special Trial Offer, which is simply the cost of shipping and handling. Click above to give it a try.

  • References
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Diurex Side Effects:

Diurex is a water pill that can work to force out fluid and that reduces weight, temporarily. With this brand, it is a rarity to find reports of side effects, but there are a few around.


“It only keeps me up and feeling jittery.”    Larry


“I did, however, experience significant chest pain and anxiety. It was crippling and made for a very long night.”    Cher


“I took some before bed (no caffeine) and quickly discovered it made me feel nauseous.”    Ree


“This is nothing but a caffeine pill. Of course it will keep you awake.”    Deacon


“I had extreme palpitations and felt sick after taking this.”    D.T. Noland


“It gives me awful acid reflux.”    Felicia


“Only problem is they gave me Charley Horse leg cramps in my calves (very painful).”    Manny


“Wow. These made my heart go crazy. They gave me palpitation. I stopped after one.”    Rene


“Made me very sick and lost a lot of my potassium in system.”    Denise


“The water pill worked for only one day and it gave me the worst stomach pain and I was pooping more than I was peeing. My poop wasn’t solid and it hurt so bad to go to the bathroom.”    Robert


Long-term weight-loss is about more than pushing out excess fluid. Leptigen, which is made with clinically tested ingredients, is our top choice for 2016.

You can learn everything about Leptigen by clicking above.

Diurex is one of those supplements that consistently come up in weight-loss conversations, so we wanted to learn more. We took a deep look at Diurex side effects. We scoured through ingredients and clinical research. Hundreds of consumer comments were also part of the process. Then, we condensed the info to give you the bottom line.

What You Need to Know

To start, Diurex is a water pill offered with ingredients like caffeine and pamabrom. You typically take two every four to six hours, as needed. The supplement is supposed to reduce fluid retention and thus help shed a few extra pounds. The bottle is small enough to throw into your bag.

The product, offered by Alva-Amco sometime after 1999, is made with natural ingredients, a positive sign. Purchases can be made through online retailers and in most retail stores. We like that some customers report good results and the company does have a strong footing in the industry, but read on…

Is Your Heart OK?

The first issue we found with Diurex side effects was heart trouble. “Your heart is one of the most important organs in the body,” says our Research Editor. “The last thing a dieter wants is to sacrifice it for the sake of losing water weight.”

“I had extreme palpitations and felt sick after taking this,” offered one user.

“I did…experience significant chest pain and anxiety. It was crippling and made for a very long night,” says another.

Nausea and Diarrhea?

Another problem with Diurex side effects, according to dieter reviews, is nausea and diarrhea. “Nausea and diarreha, which would start about 1 hour after taking. I also had a splitting head ache after taking each of my doses that day,” says one user.

“Made me sick to my stomach. Didn’t help the bloating matter of fact made it worse. I took it for one day and had to discontinue use because I felt so horrible,” offers a customer.

Another reports the same thing when the supplement is taken at night, “I took some before bed (no caffeine) and quickly discovered it made me feel nauseous.”

Our research shows something small, like nausea, is enough to derail chances of long-term success. If Diurex side effects are enough to cause problems, dieters may want to try another product.

The Science

There’s no mention of clinical research on the Diurex website, but there is some evidence the main ingredient in most formulas works. Caffeine is a known diuretic, but the price is outrageous when you can just drink a cup of coffee or take an energy pill for the same effect. At DietSpotlight, we look for scientific support that proves a product is better than other options. In this case, that’s not available.

The Bottom Line

Our look into Diurex side effects left us with a firm conclusion. We like that you can buy the supplement anywhere and the company has a strong BBB rating, but we can’t recommend it because there’s no proof it works better than common caffeine pills. We’re also concerned with reports of nausea, diarrhea and heart palpitations.

If the next point in your journey is weight-loss, we suggest trying out a supplement with no side effects that’s supported with clinical research.

Among the best supplements we’ve reviewed in 2016 is Leptigen. There are four ingredients in a proprietary blend with published scientific studies showing it helps spark metabolism and boost fat loss. There are no reports of side effects of any kind and dieters are talking about seeing some amazing results.

Also, the company responsible for Leptigen is so confident in the formula that they’re offering a Special Trial Offer, not your average bonus.

  • References
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Diurex is a diuretic designed for women to supposedly relieve menstrual cramps, bloating, and decrease water weight gain before or after their menstrual cycle.

Diurex Ingredients and Supplement Facts

Serving Size: Varies
Serving Per Container: 42
Amount per Serving % DV
Caffeine Anhydrous 50mg *
Magnesium Salicylate (NSAID) 162.5mg *

Other Ingredients: Acacia, calcium carbonate, corn starch, crospovidone, fd&c blue #1 lake, hypromellose, magnesium stearate, maltodextrin, methylene blue, microcrystalline cellulose, mineral oil, polyethylene glycol, polysorbate, shellac, silica, sodium glycolate, stearic acid, talc, titanium dioxide, triacentin

We dug deep into the Diurex ingredients to give you the details you need.

Solubolized Pamabrom

Solubolized pamabrom is a diuretic used in over-the-counter medications. The active ingredient is 8-bromotheophylline.

What is it Supposed to Do?

It works by increasing urine output and is used to treat bloating, swelling, and other signs of water weight gain, usually related to menstrual symptoms.

Clinical Research

According to a study published in Expert Opinion on Pharmacotherapy, “The clinical evidence regarding the association with pamabrom is even more scarce. Well-designed, randomised, controlled trials are required to demonstrate the efficacy of the combination of acetaminophen plus pamabrom in the treatment of primary dysmenorrhoea.”

It’s important to find solid clinical research to support the supplement you’re considering when you choose a dietary supplement for any purpose. You may want to take a look at a product like Leptigen, which is made using clinically-tested ingredients.

Caffeine Anhydrous

This is a form of caffeine without water. Caffeine is naturally found in tea and coffee, and is added to some soft drinks. It’s also available in pill form.

What is it Supposed to Do?

It is a stimulant that’s supposed to help boost the metabolism.

Clinical Research

According to a study published by the Human Behavioral Pharmacology Laboratory at the University of Vermont’s Department of Psychiatry, “These results replicate prior results and suggest that caffeine, at doses commonly found in teas and sodas, can function as a reinforcer.”

Is There Anything Out There That TRULY Works?

We have our eye on a supplement that fits the bill. Leptigen, which is formulated with ingredients that HAVE been clinically tested, may be a good option. All customers can take advantage of a Special Trial Offer, currently available through the manufacturer. Click above to give it a shot.

  • References
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Dietspotlight Author
About the Author:

Summer Banks, a content strategist at Leptigen, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 3.5. From 147 votes.
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User Comments

49 Comments on "Diurex Review"


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i would imagine taking this will cause dehydration ?

Hello. All users are different and can experience different side effects; please make sure to consult with your physician before taking this product.


Does anybody knows which one is better? Diurex ultra or diurex max? I am very concerned about this pills I’ve been reading a lot of good comments but nobody says which one is the best.


Hi, I just took the water pill for the first time ever! Right after I took it maybe 1 hour later I started to become very weak and dizzy. I couldn’t stand up without getting that blurry light head feeling. I took them because I am on a diet and eat only non fat low calorie foods and exercise but jeans got tight so I thought maybe I’m retaining water. I have a 400- 600 calorie count a day I can’t fit in my jeans for some reason I eat only veggies or yogurt. I do not know why my jeans feel tight. I want to eat like everyone else but I gain weight so easy. Even with a 500 calorie count of healthy food I still can’t lose weight!


You should never eat less than 1,500 calories….your body is in starvation mode which is why you are not losing weight/don’t feel well. Start at 1,200 calories a day and then slowly increase/add excersise.


I am thinking about using Duirex because I start retaining a lot water during my period. I also take prescription medications at night and in the morning. Before I take take these I would like to know: Will Duirex deplete my prescription medications??


Diurex is known to interfere with a few different medications. I would definitely talk to a doctor.


Hi Hayley. Please consult with your physician before taking this product because of possible interactions with your medications.


I started using diurex because I was bloated all the time period or not. I also gained about 10 pounds in 3 weeks and couldn’t figure out why. My mom suggested maybe I was retaining fluid and try a water pill. So I started taking it I went from 164 to 160 over night. I don’t feel as bloated, I’m only on day 2 but I feel good about taking this on a regular basis.

Candy Muncy Poole

I’m looking at the list of ingredients on Diurex Water pills and the only two stated (active) ingredients ARE caffeine and Magnesium Salicylate (NSAID)in contradiction to the description and ingredients listed above.

Hi Candy. Thank you for pointing out the incorrect information. The ingredients listed were for Diurex Max, instead of Diurex. It has since been changed.

Chrissy Vedder

Now have a bladder infection… Is this a side effect of Diurex Max??

Hi Chrissy. While there’s no mention of this being a side effect of Diurex Max, you may want to contact a doctor if this reactions continues.

Susan Amin

Using Diurex Max for the first time make me pee a lot and i must say please be aware
if you have a sensitive stomach stay away from Diurex Max
this product causes diarrhea …. but its cleans me out
i continued to used the product
I look up the side effect online, but there isn’t any


I have been using Diurex Ultra 2 pills a day for 2 days now but I have been urinating normal. I do not have to Uring more and usual is that normal or not?


I wonder if it would help get rid of next day drinker bloating. Any help would be apreciated

Your Name

Worked for me after too much champagne


can diurex cause stomac issues ?

Hi Trona. This question may be better suited for your physician.


I have taken it in the past for water weight gain and it worked great. Last night and this morning I took a capsule and have had horrible stomach pain. So, I was also wondering if it causes stomach issues?


Hello JC. All users are different and can experience different side effects, but please make sure to consult with your physician before continuing taking this product if you are still having side effects.

big red

this really works! lost 8lbs. of water weight in 2 days


I tried this last month for my period bloating. And it seemed to work. I didn’t feel bloated. But I didn’t have any weight loss results to my satisfaction. Except for about 4 lbs that came back right after my period. You definitely need to eat before you take it. I took some before bed (no caffeine) and quickly discovered it made me feel nauseous. I took two tums to calm the feeling of wanting to get sick. If your trying to loose weight I would recommend diet, exercise, and some good appetite suppressant. Like Zyatonix. Free warning Zyatonix has unpleasant side affects too.




do these contain asprin?

Christine Quinn

How long will my pee stay green after taking Duirex water pills?


Not long at all. Also, I lost 25 pounds in 8 months on Diurex; BUT I also cut my sodium intake down quite a bit by not eating any processed foods (like frozen dinners, pizzas, salty snacks, etc.), eating Greek yogurt with fresh fruit 7 drinking a lot of sparkling water constantly. Also, threw in walking in pool for 2-3 hours for 1st 2 months. Also, cut way down on sweets. I’m in my early 60’s & cut my size from 12 to size 6. It can be done. Plus no large meals after 8PM at nite (I stay up til midnite).


i bought diurex max. cant find box. how often are you supposed to take them?

Hi Darlene. According to the Diurex Max label on the official website:

Adults: One (1) caplet after breakfast with a full glass of water.
■ Dose may be repeated after 6 hours, not to exceed four (4) caplets in 24 hours.
■ Start taking 5 or 6 days before onset of period and continue until desired relief
is obtained or end of period. ■ Drink 6 to 8 glasses of water daily. ■ For use by
normally healthy adults only. ■ Persons under 18 years of age should use only
as directed by a doctor.

Your Name

Every 6 hours…. After u eat in the morning… Glass of water….nomore than 6 pills a day


Your article stated, if I am correct, that, Diurex does NOT contain aspirin or CAFFEINE.
I purchased Diurex Water Pills ( blue & pale green box from Walgreens) It clearly states Caffeine 50mg.
Do the pills work?
It says to take 2 pills every 4 hours, 8 total per day.
Even with 8 pills… I am still very bloated.
I’ll have to see what the Doctor prescribes.
Online, Walgreens advertised the pills as 3.99, and the store charged 5.99.
As of today…, unfortunately, (and, perhaps I might be suffering of some oddball situation…), but,
I presently believe the product to be totally worthless.

I also was unable to sleep until 3AM………
I am not certain that this product is good for anyone.

The Health Dept… should verify all these products… Why foolishly spend money on products that do not work, and, or, might detrimentally affect someone’s well being?


Did you lose any of the swelling, taking this? I just got it because I have been on steroids for so long and I am tired of having a swollen face/ body.

Dr. Dad

Diurex works, but you need to buy the right one. I read labels. There is one who’s main ingredient is caffeine. I bought the one who’s main ingredient is Solubilized Pamabrom. Whether or not it works for hypertention I don’t know but my wife took it and she lost 8lbs in 2 days, however she was a little peeved about urinating so much.

Patricia Williams

How do you think she was going to release the water from her body??? Peeing is the only way!! Ugh!!


so which one should i get? the one with caffeine or solubilized pamabrom?!?!


solubilized pamabrom


I have been using this for a bit now and I went to the doctors the first time and I lost 8 lbs the first time then when I went back 2 weeks later another 7 smile

California Girl

Do not waste your money with Diurex, I took it for a week and saw no results. The only thing I noticed was that my urine was blue-ish, other than that nothing. It is such a waste of money.