Updated: 01/10/2017 - Site operated by Leptigen

Diurex Review - Does This Diuretic Pill Work? Are side effects and lack of real weight-loss results deal breakers?

  • 40 User Comments
  • Rating: 3.5. From 140 votes.
By Summer Banks Dec 12, 2016

I’m here to cut through the noise and get you to the bottom line on Diurex. We dug deep and came up with a comprehensive review, closely examining the ingredients, side effects, scientific studies and overall customer care. We additionally read tons of comments from all over the web. At this point we compacted and summarized to give you with the info you need.

Diurex Readers: Click here to find out why we're giving away samples of our product, Leptigen.

What You Need To Know

First off, Diurex is a series of supplements made by Alva-Amco Pharmacal Companies, Inc. The key ingredients are solubolized pamabrom and caffeine anhydrous. [1] [2] There are six different formula posted on the official website, which include Aquagels, MAX Water Caplets, Ultra, Water Pills, WaterCaps and Water Capsules. These are intended to “temporarily” reduce bloating and excess water weight. You have to read the directions on each label to find out how many to take.

We are uncertain when Diurex was first released, but the company itself dates back to 1904. You can buy the products in common drugstores, as well as online. You are encouraged to drink plenty of water daily while using the formula, but read on…

Side Effects – “Be Cautious?”

The first issue we realized with Diurex ingredients was that some dieter experienced side effects. “Whenever you choose a new supplement you need to take into consideration how it will make you feel,” says our Research Editor. “In this case, users have reported some irritating reactions.”

One customer commented, “Diurex causes diarrhea!”

“Doesn’t really work, just makes me nauseous,” said another user.

Weight-Loss Results – “They’re Lacking”

Just so you are aware, Diurex pills do not burn off fat, suppress appetite or elevate metabolism, which means they will not help with long-term fat loss. One customer revealed, “Didn’t lose a single pound. These just make you pee a lot!”

Another user said, “No weight-loss from this! Don’t waste your money!”

According to our research, if there is some particular part of a supplement or weight-loss program that is very problematic or burdensome (lack or real results, side effects, a federal warning) the chances of long-term success are pretty low. This means if Diurex pills do cause ill feelings, this could be a serious dilemma.

The Science – “Is There Clinical Support?”

Actual science is not addressed on the company website for Diurex. However, this product does contain proven diuretics, so it should help remove excess water weight from the body. Then again, you should not expect it to help you lose excess body fat. After all, it does not contain proven fat burners or metabolism boosters. At DietSpotlight, we prefer to see published clinical studies that prove it works and that’s not something this supplement has to offer.

The Bottom Line – Does Diurex Work?

Hold up just one more minute so we can give you the final details on this one. We like that the ingredients in Diurex are offered online and it can help you with water retention, but we don’t feel comfortable recommending this to dieters because it is not clinically proven to boost weight-loss. We’re also concerned that it may interfere with some prescription medications.

If you need to see faster fat loss results and a slimmer figure, we encourage you to choose a diet supplement that is packed with clinically proven ingredients, does not cause harsh side effects and is supported by plenty of positive user feedback.

Among the best products we’ve seen in 2016 is one called Leptigen. This weight-loss pill contains four proven ingredients that have been shown in published scientific studies to boost metabolism and increase fat loss. We have not seen any talk of harmful side effects and user feedback around the web shows people are seeing significant results.

Also, the company that makes Leptigen is so confident in the formula they’re offering a Special Trial Offer, which is quite a good sign.

Previous Diurex Review (Updated July 9, 2014):

What You Should Know

Diurex is a dietary supplement that is manufactured by Alva-Amco Pharmacal Companies, Inc., a company founded in 1904. It is marketed towards both women and men. This product aims to assist with discomforts by reducing "excess body water." There are actually five separate versions of Diurex for women; Diurex Aquagels, Diurex Water Capsules, Diurex Water Caplets, Diurex PMS and Diurex Water Pills. There do not appear to be any customer testimonials for this product. Diurex supplements can be purchased in most common drugstores and grocery stores.

The active ingredient found in Diurex supplements is Solubilized Pamabrom (diuretic that is stated to assist with bloating). Diurex endeavors to aid women with monthly swelling, bloating, water weight gain and puffiness due to their menstrual cycle. These diet supplements are stated to be free of aspirin and caffeine. Unfortunately there are no free trial samples of Diurex products available through the official website. Diurex is available without a prescription, but doesn't appear to be offered with a 100% money-back/satisfaction guarantee. There is no diet plan or fitness regimen recommended with Diurex supplements. The version of Diurex for men also aims to help minimize unwanted water weight. There doesn't appear to be any actual clinical research provided on the official website. This product sells for $25.74 for a 60 count of pills.

List of Ingredients

Solubilized Pamabrom, FD&C Blue #1, Gelatin, Glycerin, Hypromellose, Polyethylene Glycol, Povidone, Propylene Glycol, Purified Water, Sorbitol and Titanium Dioxide.

Product Features

Diurex is a dietary supplement that is claimed to assist women and men with water weight reduction and bloating. This product comes in five different forms and is directed to be taken with water after breakfast. The primary active component incorporated into Diurex is Solubilized Pamabrom, a diuretic that is stated to assist with bloating. This weight reduction supplement can be acquired in most typical grocery stores and drugstores. There is no clinical data offered on the website for Diurex supplements. Diurex sells for $25.74 and is available without a prescription.


  • Diurex can be easily and conveniently purchased in most common drug and grocery stores.
  • Diurex is available to both men and women.
  • A full ingredient list is offered on the official website for Diurex supplements.


  • There are no customer testimonials for Diurex offered on the official website.
  • Some ingredients found in Diurex supplements may not be suitable for some individuals. (See Diurex Side Effects).
  • Diurex does not actually sell conveniently through the official website.
  • Using a diuretic to achieve significant weight loss can be unhealthy, and any weight loss users do see will likely not last very long.
  • Diurex supplements are not offered with a 100% money-back guarantee.
  • There are no free trial samples of Diurex products available through the official website at this time.


Diurex is pitched rather differently than most weight reduction supplements. This product doesn't endeavor to suppress the user's appetite, burn calories, boost energy levels, assist the metabolism or burn away unwanted fat. Diurex mainly addresses water weight gain and the menstrual cycle of women. Therefore it's probably wise to investigate a number of other diet drugs before selecting a diuretic such as Diurex. In the end, it would be more reassuring to see some clinical data posted on the official website, along with some customer testimonials for Diurex and a 100% money-back guarantee.

Diurex Questions & Answers:

We picked apart hundreds of user comments about Diurex into this helpful FAQ.

What are the side effects of Diurex?

Some Diurex side effects may include frequent urination, increased heartrate and blood pressure, sleeplessness, irritability and nervousness.

What are the ingredients in Diurex?

Diurex ingredients are caffeine, magnesium salicylate, pamabrom, calcium carbonate, calcium sulfate, cornstarch, d&c yellow no. 10 lake, ethyl vanillin, fd&c blue no. 1 lake, fd&c blue no. 2 lake, hypromellose, magnesium silicate, magnesium stearate, mineral oil, polyethylene glycol, sodium lauryl sulfate, stearic acid and titanium dioxide.

Does Diurex work?

There’s no solid science linking the ingredients in Diurex to weight-loss. We found studies supporting the effectiveness of caffeine, but nothing that is just about this supplement.

You may want to think about changing out Diurex with a supplement like Leptigen, which contains ingredients that have been clinically tested.

How much does Diurex cost?

Diurex costs $7.56. Considering the supplement is available through various retailers, the price could change.

How should I take Diurex?

You should take three to four Diurex capsules while symptoms persist. The company suggests not taking more than four pills in one day.

Can I take Diurex if I have a health condition?

Women who are pregnant or nursing, those taking prescription medications of any kind, people with health conditions or anyone under 18 years of age should contact a healthcare professional prior to using any dietary supplement, including Diurex.

What do users like about Diurex?

Some users liked that Diurex was easy to take and available through multiple retailers.

What do users NOT like about Diurex?

We found that some users didn’t like the side effects of Diurex and that the supplement didn’t help with weight-loss.

How do I contact the Diurex customer service department?

You can contact the Diurex customer service department by calling a representative at 1-800-792-2582, mailing letters to Alva-Amco Pharmacal Co. Inc. 7711 Merrimac Ave. Niles, IL 60714-3423 or by emailing customer_service@alva-amco.com.

What is the active ingredient in Diurex?

The active ingredient in Diurex is caffeine.

How long can I use Diurex?

You can use Diurex continuously for 10 days.

Can men use Diurex?

Yes, men can use Diurex. As a precaution, you should consult with a healthcare provider prior to using weight-loss supplements.

Does Diurex come with a guarantee?

There’s no mention of a guarantee with Diurex, likely because it is not sold by the manufacturer. You will need to visit the retailers selling the product for details about the return policy.

Do you know of any special deals or discounts on Diurex?

We didn’t find any special deals or discounts on the Diurex official website. However, the last few months have been buzzing, considering our readers have been taking advantage of Leptigen’s Special Trial Offer, which is simply the cost of shipping and handling. Click here to give it a try.

  • References
  • 1. (). . .

Diurex Side Effects:

Diurex is a water pill that can work to force out fluid and that reduces weight, temporarily. With this brand, it is a rarity to find reports of side effects, but there are a few around.


“It only keeps me up and feeling jittery.”    Larry


“I did, however, experience significant chest pain and anxiety. It was crippling and made for a very long night.”    Cher


“I took some before bed (no caffeine) and quickly discovered it made me feel nauseous.”    Ree


“This is nothing but a caffeine pill. Of course it will keep you awake.”    Deacon


“I had extreme palpitations and felt sick after taking this.”    D.T. Noland


“It gives me awful acid reflux.”    Felicia


“Only problem is they gave me Charley Horse leg cramps in my calves (very painful).”    Manny


“Wow. These made my heart go crazy. They gave me palpitation. I stopped after one.”    Rene


“Made me very sick and lost a lot of my potassium in system.”    Denise


“The water pill worked for only one day and it gave me the worst stomach pain and I was pooping more than I was peeing. My poop wasn’t solid and it hurt so bad to go to the bathroom.”    Robert


Long-term weight-loss is about more than pushing out excess fluid. Leptigen, which is made with clinically tested ingredients, is our top choice for 2016.

You can learn everything about Leptigen by clicking here.

  • References
  • 1. (). . .

Diurex is a diuretic designed for women to supposedly relieve menstrual cramps, bloating, and decrease water weight gain before or after their menstrual cycle.

Diurex Ingredients and Supplement Facts

Serving Size: Varies
Serving Per Container: 42
Amount per Serving % DV
Caffeine Anhydrous 50mg *
Magnesium Salicylate 162.5mg *

Other Ingredients: Acacia, calcium carbonate, corn starch, crospovidone, fd&c blue #1 lake, hypromellose, magnesium stearate, maltodextrin, methylene blue, microcrystalline cellulose, mineral oil, polyethylene glycol, polysorbate, shellac, silica, sodium glycolate, stearic acid, talc, titanium dioxide, triacentin

We dug deep into the Diurex ingredients to give you the details you need.

Solubolized Pamabrom

Solubolized pamabrom is a diuretic used in over-the-counter medications. The active ingredient is 8-bromotheophylline.

What is it Supposed to Do?

It works by increasing urine output and is used to treat bloating, swelling, and other signs of water weight gain, usually related to menstrual symptoms.

Clinical Research

According to a study published in Expert Opinion on Pharmacotherapy, “The clinical evidence regarding the association with pamabrom is even more scarce. Well-designed, randomised, controlled trials are required to demonstrate the efficacy of the combination of acetaminophen plus pamabrom in the treatment of primary dysmenorrhoea.”

It’s important to find solid clinical research to support the supplement you’re considering when you choose a dietary supplement for any purpose. You may want to take a look at a product like Leptigen, which is made using clinically-tested ingredients.

Caffeine Anhydrous

This is a form of caffeine without water. Caffeine is naturally found in tea and coffee, and is added to some soft drinks. It’s also available in pill form.

What is it Supposed to Do?

It is a stimulant that’s supposed to help boost the metabolism.

Clinical Research

According to a study published by the Human Behavioral Pharmacology Laboratory at the University of Vermont’s Department of Psychiatry, “These results replicate prior results and suggest that caffeine, at doses commonly found in teas and sodas, can function as a reinforcer.”

Is There Anything Out There That TRULY Works?

We have our eye on a supplement that fits the bill. Leptigen, which is formulated with ingredients that HAVE been clinically tested, may be a good option. All customers can take advantage of a Special Trial Offer, currently available through the manufacturer. Click here to give it a shot.

  • References
  • 1. (). . .
Get Your Sample Today »
About the Author:

Summer Banks, a content strategist at Leptigen, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 3.5. From 140 votes.
Please wait...
Diurex Review

How Does Diurex Compare?

User Comments

40 Comments on "Diurex Review"


Sort by:   newest | oldest | most voted

I am thinking about using Duirex because I start retaining a lot water during my period. I also take prescription medications at night and in the morning. Before I take take these I would like to know: Will Duirex deplete my prescription medications??

Hi Hayley. Please consult with your physician before taking this product because of possible interactions with your medications.

I started using diurex because I was bloated all the time period or not. I also gained about 10 pounds in 3 weeks and couldn’t figure out why. My mom suggested maybe I was retaining fluid and try a water pill. So I started taking it I went from 164 to 160 over night. I don’t feel as bloated, I’m only on day 2 but I feel good about taking this on a regular basis.

I’m looking at the list of ingredients on Diurex Water pills and the only two stated (active) ingredients ARE caffeine and Magnesium Salicylate (NSAID)in contradiction to the description and ingredients listed above.

Now have a bladder infection… Is this a side effect of Diurex Max??

Using Diurex Max for the first time make me pee a lot and i must say please be aware
if you have a sensitive stomach stay away from Diurex Max
this product causes diarrhea …. but its cleans me out
i continued to used the product
I look up the side effect online, but there isn’t any

I have been using Diurex Ultra 2 pills a day for 2 days now but I have been urinating normal. I do not have to Uring more and usual is that normal or not?

I have gained nearly 30 pounds in fluid over the past month. Doc recommended trying this. I did and lost 10 pounds of water weight overnight. I did, however, experience significant chest pain and anxiety. It was crippling and made for a very long night. I bought the Caffeine Free Aquagels and they really did help me get rid of some of this fluid!

I wonder if it would help get rid of next day drinker bloating. Any help would be apreciated

Worked for me after too much champagne

can diurex cause stomac issues ?

I have taken it in the past for water weight gain and it worked great. Last night and this morning I took a capsule and have had horrible stomach pain. So, I was also wondering if it causes stomach issues?

Hello JC. All users are different and can experience different side effects, but please make sure to consult with your physician before continuing taking this product if you are still having side effects.

this really works! lost 8lbs. of water weight in 2 days

I tried this last month for my period bloating. And it seemed to work. I didn’t feel bloated. But I didn’t have any weight loss results to my satisfaction. Except for about 4 lbs that came back right after my period. You definitely need to eat before you take it. I took some before bed (no caffeine) and quickly discovered it made me feel nauseous. I took two tums to calm the feeling of wanting to get sick. If your trying to loose weight I would recommend diet, exercise, and some good appetite suppressant. Like Zyatonix. Free warning Zyatonix has unpleasant side affects too.


do these contain asprin?

How long will my pee stay green after taking Duirex water pills?

Not long at all. Also, I lost 25 pounds in 8 months on Diurex; BUT I also cut my sodium intake down quite a bit by not eating any processed foods (like frozen dinners, pizzas, salty snacks, etc.), eating Greek yogurt with fresh fruit 7 drinking a lot of sparkling water constantly. Also, threw in walking in pool for 2-3 hours for 1st 2 months. Also, cut way down on sweets. I’m in my early 60’s & cut my size from 12 to size 6. It can be done. Plus no large meals after 8PM at nite (I stay up til midnite).

i bought diurex max. cant find box. how often are you supposed to take them?

Every 6 hours…. After u eat in the morning… Glass of water….nomore than 6 pills a day

Your article stated, if I am correct, that, Diurex does NOT contain aspirin or CAFFEINE.
I purchased Diurex Water Pills ( blue & pale green box from Walgreens) It clearly states Caffeine 50mg.
Do the pills work?
It says to take 2 pills every 4 hours, 8 total per day.
Even with 8 pills… I am still very bloated.
I’ll have to see what the Doctor prescribes.
Online, Walgreens advertised the pills as 3.99, and the store charged 5.99.
As of today…, unfortunately, (and, perhaps I might be suffering of some oddball situation…), but,
I presently believe the product to be totally worthless.

I also was unable to sleep until 3AM………
I am not certain that this product is good for anyone.

The Health Dept… should verify all these products… Why foolishly spend money on products that do not work, and, or, might detrimentally affect someone’s well being?

Did you lose any of the swelling, taking this? I just got it because I have been on steroids for so long and I am tired of having a swollen face/ body.

Diurex works, but you need to buy the right one. I read labels. There is one who’s main ingredient is caffeine. I bought the one who’s main ingredient is Solubilized Pamabrom. Whether or not it works for hypertention I don’t know but my wife took it and she lost 8lbs in 2 days, however she was a little peeved about urinating so much.

How do you think she was going to release the water from her body??? Peeing is the only way!! Ugh!!

so which one should i get? the one with caffeine or solubilized pamabrom?!?!

solubilized pamabrom

I have been using this for a bit now and I went to the doctors the first time and I lost 8 lbs the first time then when I went back 2 weeks later another 7 smile

Do not waste your money with Diurex, I took it for a week and saw no results. The only thing I noticed was that my urine was blue-ish, other than that nothing. It is such a waste of money.

My dad and I both have been trying to lose weight forever! Neither of us are obese, just trying to shed acouple pounds. He lost 7 pounds using this pill in 4 days. After he told me that I bought it. I started using it roughly 5 days ago and I feel like I’m losing weight. I don’t weigh myself, but my jeans are fitting much better and my tummy doesnt look bloated. It makes you pee alot and yes the green is normal.. it tells you that on the box. I’m for sure going to continue using Diurex and would highly suggest it for anyone trying to shed afew. Of course the weight you lose can come back.. as with any diet… but take this pill, eat healthier and smaller portions, and drink water instead of soda an you’ll be good to go! smile

does this help hypertension?