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Zyrexin Review - 16 Things You Need to Know

Zyrexin is a blue pill made for men with difficulty achieving an erection. It uses a blend of natural ingredients to produce erections in men in less than an hour. Zyrexin is said to work “the very first time” a man uses it. Our research team decided to see what they could find out about Zyrexin and how well it works.

Although the product is widely sold, the research team was immediately concerned about the lack of scientific research that has been conducted using some of the ingredients. After that, they looked at potential side effects, the background of the makers, and what users of Zyrexin are saying. Finally, we wrapped all of the information into this concise report that brings you all the information you need.

Zyrexin can be purchased through their Official Site.

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What is Zyrexin?

Zyrexin is a supplement used to help men with erectile dysfunction achieve erections. It is made with a tuber vegetable used in traditional medicine as an aphrodisiac.

Zyrexin comes as a blue capsule and claims impressive results in just 35 minutes. The effect is supposed to last for 24 hours, which means that men should be able to take it at any time of the day and still be ready for six hours later.

The makers of Zyrexin say that it is the only natural mixture to receive a patent in the United States for use as a male enhancement product. But, here’s the thing, having a patent doesn’t necessarily mean that a product works. It only says that the makers are protecting it from being copied by other companies.

Zyrexin benefits

How Did Zyrexin Start?

Zyrexin comes from a company called Superbalife International LLC. The company is based in Los Angeles, CA and was founded in 2004. Superbalife makes nutraceuticals, which are products made from food sources that are supposed to have health benefits. They specialize in creating products specifically for men’s health.

The official website says that their products are all made in the United States in facilities that are inspected by the FDA. (Note: This does not mean the products themselves are FDA approved, only that the FDA makes sure their products are packaged correctly and the manufacturer follows safety rules.)

The company is not currently accredited by the Better Business Bureau (BBB). They have a D- rating, but no customer reviews.

Although there are no reviews of Superbalife International LLC on the BBB’s website, there are four complaints filed against the company. Three of the claims have to do with the company’s products or services. One is about billing issues, and the remaining charge is about delivery.


Zyrexin Claims

The claims made about Zyrexin are impressive. If they prove true, Zyrexin might be the miracle pill that men are looking for. The Zyrexin claims include:

  • Works in as little as 35 minutes
  • The effects last for 24 hours
  • Works the first time it is used
  • No side effects
  • Effective

Zyrexin ingredients


Zyrexin Ingredients

The official Zyrexin website states that the supplement contains a natural PDE-5 inhibitor. The official website does not provide an image of the label or even a complete list of ingredients. The only ingredient they disclose is something called Butea Superba. In reality, the supplement contains much more.

According to the product’s label, it contains a proprietary blend of herbs. Some of the ingredients in the combination are:

  • Epimedium Extract
  • Yohimbe Extract
  • Xanthoparmelia Scabrosa Extract
  • Ginkgo Extract
  • Cnidium Extract
  • Velvet Bean Extract
  • Butea Superba Extract
  • L-Arginine

What is a PDE-5 Inhibitor?

The makers of Zyrexin say that Butea Superba is “the only natural PDE-5 inhibitor know [sic] in nature.” A PDE-5 inhibitor is a substance that stops cyclic guanosine monophosphate (cGMP) from breaking down. This allows blood vessels to remain dilated so that blood flows more smoothly. PDE-5 inhibitors work individually on type-5 phosphodiesterases, a form of cGMP that exists in the erectile tissue of the penis and the lungs, LiverTox claims.

Does Zyrexin Work?

Zyrexin promises outstanding results but whether it can deliver depends on whether there is clinical evidence to show the ingredients are active. The Zyrexin website doesn’t provide any links to studies using the supplement or any of its elements. However, our research team took the time to look into the science behind the ingredients. Here is some of what they found.

Yohimbe Extract

Yohimbe is a kind of tree that grows in parts of Africa. The bark of the tree contains yohimbine, which is used in a standardized form (yohimbine hydrochloride) to make prescription medications for erectile dysfunction.

Zyrexin ingredients yohimbine

Although yohimbine has been proven effective, there isn’t much research concerning Yohimbe used in dietary supplements. Also, according to the National Center for Complementary and Integrative Health, dietary supplements that contain Yohimbe vary in the amount of yohimbine in them. They also state, “Yohimbe sold as a dietary supplement may not work like the prescription medication that contains yohimbine.”

The amount of Yohimbe, or its active ingredient yohimbine, is not disclosed on the Zyrexin label. It is only listed as one of the ingredients in the proprietary blend. Therefore, there’s no way to know if there’s enough of the substance to have any effect.

Zyrexin ingredients

Ginkgo Extract

Ginkgo, or ginkgo biloba, is an ancient tree species. It’s believed to be one of the oldest species of tree known to humankind. Although the seeds are poisonous, they were once given to royalty to treat senility.

According to MedicalNewsToday, gingko is thought to have health benefits because it contains flavonoids and terpenoids, which are both antioxidants. Antioxidants help to protect cells from free radicals.

Today, ginkgo extract made from the leaves of the tree is used in supplements to treat:

  • Eye conditions
  • Leg pain due to narrowing arteries

According to the National Center for Complementary and Integrative Health, there have been some studies conducted using ginkgo to determine if it has health benefits and how it affects people. The studies have yielded “no conclusive evidence that ginkgo is helpful for any health condition.”

Velvet Bean Extract

The velvet bean, or Mucuna pruriens, is a kind of legume that grows in Africa and Asia. It is often grown as a green manure crop because it fixes nitrogen in the soil. Also, it is used as silage for livestock.

Velvet bean contains a substance called L-DOPA. People who are sensitive to L-DOPA may experience problems when taking the substance, such as nausea, vomiting, and cramping. They may even have an erratic heartbeat.

In traditional medicine, velvet bean has been used to treat infertility and as an aphrodisiac.

Velvet Bean

Some studies indicate velvet bean may be useful in treating fertility problems. A study published in a journal titled Fertility and Sterility indicates that velvet bean may improve sperm quality. The study involved 75 men with fertility problems and 75 men without fertility problems. The subjects were treated with mucuna pruriens. After the study, the researchers determined that taking the substance “regulates steroidogenesis and improves semen quality in infertile men.”

Butea Superba Extract

Butea Superba is the ingredient that the makers of Zyrexin give all the credit to on their website. It is a shrub that grows in Thailand, Vietnam, and India. The roots of the plant are tuberous and contain flavonoids and sterol compounds. In traditional medicine, Butea Superba is used by Thai men to boost sexual vigor.

Although it is used in supplements to help men achieve erections, at present there is not enough evidence to show that it is effective.

Researchers published a study in the journal BJU International that showed the results of Butea Superba are inconsistent at best. An initial investigation showed positive effects on erectile dysfunction. However, a second double-blind study failed to duplicate the results. The researchers believed that the first batch of Butea Superba used had been mixed with a PDE-5 inhibitor. Their suspicions were later confirmed by the company that supplied the substance.


L-arginine is an amino acid that the body uses for proper blood flow. According to Examine, however, research shows that taking a supplement containing l-arginine may not have that same effect. Studies show that although l-arginine supplementation might activate nitric oxide, its effects are not reliable. This means that it is also not reliably useful for increasing blood flow.


Zyrexin Benefits and Results

Even though the makers of the supplement say that the Zyrexin benefit is men being able to achieve erections, our researchers didn’t find any clinical research to support that claim. Men who take Zyrexin may benefit from the antioxidants in a few of the ingredients, but that’s about it.

Zytrexin benefits

How to Take Zyrexin

The instructions for Zyrexin say that men should take one or two tablets about 45 minutes before sexual activity. Men should not take more than two tablets per day.

Side Effects

Potential Zyrexin Side Effects

The makers of Zyrexin say that the product has been “taken over 100 million times…without any reports of side effects.” The customer comments we read indicate that’s not the case. As with any supplement, some people may have no problems when taking it, but others might experience anything from mild side effects to ones that are concerning.

Some of the potential side effects of ginkgo are:

  • Headaches
  • Constipation
  • Dizziness
  • Upset stomach

Also, the Mayo Clinic cautions against certain groups of people using supplements containing ginkgo, such as:

  • Older people
  • Women who are pregnant

Zytrexin side effects

Possible side effects are:

  • Rapid heartbeat
  • Trouble breathing
  • A painful erection that does not go away
  • Nausea
  • Bloating
  • Vomiting
  • Abnormal movement
  • Abdominal pain
  • Bloating
  • Diarrhea
  • Gout
  • Inflamed airways

As for Butea Superba, there just hasn’t been enough research conducted to determine if the substance is safe for human use.

Zytrexin warnings


Zyrexin Product Warnings

The Zyrexin label says that the product should not be used by anyone under the age of 18 or by women who are pregnant or nursing.

Where You Can Buy Zyrexin

Zyrexin can be purchased through the official website. It is also available through several retailers, including:

  • Walmart
  • CVS Pharmacy
  • Rite Aid
  • Walgreens

Zytrexin cost


What Does Zyrexin Cost?

The official website offers package deals to reduce the Zyrexin cost. At the time of this review, the Zyrexin deals are:

  • Buy two bottles for $29.95.
  • Buy two bottles for $59.95 and get one bottle free.
  • Buy three bottles for $89.95 and get two bottles free.

Those might sound like good deals until you find out that each bottle contains only ten pills.

Any Zyrexin Lawsuits?

The research team didn’t find any lawsuits associated with Zyrexin. However, the Canadian government did issue a “Foreign Product Alert” because the supplement contains yohimbine, the active ingredient in Yohimbe. In Canada, yohimbine is a prescription drug and should not be taken without the advice of a doctor.

Is Zyrexin a Scam?

We hesitate to call Zyrexin a scam as there doesn’t appear to be any evidence of questionable business practices, which is usually the hallmark of fraud. However, we aren’t convinced that the supplement will help men with erectile dysfunction. Instead, it appears to be an overpriced herbal supplement with little effect.

Zyrexin Alternatives

There’s no shortage of male enhancement products on the market, and many of them claim to help men with erectile dysfunction. Some Zyrexin alternatives are:

Zytrexin alternatives

Bottom Line

What Users Are Saying

“Zyrexin worked well for me…only side effect was a bit of the jitters. It did what the label claimed!”

“Did nothing for me. Not a good product.”

“Consistent Product. Absolutely. NO PROBLEMS. Excellent Product. Would Re Order if I were able.”

Bottom Line on Zyrexin

Is it time to run to the store for a bottle of Zyrexin? We don’t think so. It’s true that there is evidence suggesting that some of the ingredients might improve fertility but not that they help with erectile dysfunction. The information our research team discovered left us with some concerns, such as:

  • Many customers reported having uncomfortable and even frightening side effects.
  • We found little evidence suggesting the ingredients in Zyrexin do anything to allow men to achieve erections.
  • Considering there are only ten pills in a bottle, the cost is quite high.

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What is Zyrexin?

Zyrexin is a supplement that claims to help men achieve better erections through traditional herbs.

Is Zyrexin for weight loss?

No, Zyrexin is not for weight loss.

What are the Zyrexin ingredients?

The active ingredients in Zyrexin include velvet bean, cnidium, butea superba, l-arginine, epidemium, xanthoparmelia scabrosa, and yohimbe.

Are there Zyrexin side effects to know about?

Possible side effects of Zyrexin include:

  • Arrhythmia
  • Bloating
  • Breathing complications
  • Constipation
  • Cramping
  • Diarrhea
  • Dizziness
  • Gout
  • Headache
  • Nausea
  • Painful erection
  • Tachycardia
  • Vomiting

Additionally, since the supplement contains yohimbe, additional aide effects may include anxiety and bloating.

Is Zyrexin safe?

Zyrexin is safe for most healthy men following the recommended dosage. Seek medical advice if you have a medical condition such as seizures, take medication, or are under 18 years old.

Where can I buy Zyrexin?

Zyrexin can be purchased using their Official Site.

Is Zyrexin for men or women?

Zyrexin is for men only.

Where can I buy Zyrexin?

Zyrexin can be purchased from the manufacturer’s website and many local retail pharmacies.

Is there a Zyrexin free trial or free sample?

The manufacturer home site states that, due to demand, no free samples are currently available.

What is the most common Zyrexin complaint?

The most common consumer complaint are extreme side effects and that the product does not address erectile dysfunction.

What are some products similar to Zyrexin?

Products that fall in the same category as Zyrexin include Nugenix, Performix Super Male T, and Ultra Man Max.

25 Zyrexin Reviews

  • Awesome
    Joe (Verified Purchase)


  • Anonymous (Verified Purchase)

    I took 2 pills each time and after and hr there still was no sign of desire. went to sleep and woke up 2 hrs later with stomach cramps and felt a caffeine rush. Not good.

  • Zyrexin bad side affects
    Anonymous (Verified Purchase)

    Dont waste money on this spam medicines like zyrexin,tried it didn’t work at all and infact gives you bad side affects like nausea and shortness of breath.

  • Awesome Climax!!
    Craig (Verified Purchase)

    I’m 49 and tried Zyrexin. Increased stamina and enhanced climax. Doesn’t give the stamina you get with Extenz. But, the quality of sex is amazingly better. I don’t necessarily NEED any enhancements. But, then my car doesn’t NEED a supercharger. So, while I can’t speak for results for treating ED, I can say that better is just plain better. Even when flaccid you’ll notice improved blood flow.

  • Works, but.........
    Moon (Verified Purchase)

    At 60 plus years of age, I need help in sexual activity. I bought this product after spending a $90 copay for generic viagra, and later a $100 copay for generic cialis. To be honest, I bought it because it was under $12 a bottle, and the others were about $30. I did not tell my wife I had taken anything, and she noticed something was different immediately. Better than any prescription I had ever used. Side effect: erection did not go away. (But who complains about that after what I had been through before?) And, I did not sleep much at all all night. Some kind of stimulant. No nausea or anything else. Will try one pill next time. But this pill overcomes ED. My case is severe.

    • Taylor Izzo

      Hi Moon,

      Please make sure to contact your physician if you continue to experience side effects with this product

  • WARNING- Do not take!
    Brett (Verified Purchase)

    I had brutal urinary retention and felt like i got kicked in the balls…..so basically its an “anti-viagra”. Everything thats great about viagra…..Zyrexin did the opposite. Hard = flacid, relief = ball pain, red skin. guys, you know that stoked feeling after you get laid?? I had a TIA or “mini-stroke about 120 minutes after i took 1. On the the positive side ….any body feeling suicidal? Take 2 and i bet its faster than waling in front of a speeding train.

    • Taylor Izzo

      Hello Brett,

      Please make sure to contact your physician if you continue to experience side effects with this product

      • Colin Gresham

        I had the same effect. Chills, sweats, ball pain, nausia, uncontrollable shakes, anxiety, and a complete and utter feeling of fear.

        • Taylor Izzo

          Hi Colin,

          Please contact your physician if you continue to experience these side effects.

  • Just take one
    Norman (Verified Purchase)

    I did feel the insomnia and very minor shakiness but it worked very well. Taking much earlier in the day and sometimes only one. I only use it once a week or so.

    • Phil

      I don’t take anything with yohimbe in the engredients.

  • It worked!
    John is my middle name. (Verified Purchase)

    I had no faith in it. But it worked like a charm! A lot of health warnings of who should not take it. I should not take it because I have almost every condition mentioned. But maybe if I just use it a couple times a month, I should be ok. I have only tried horny goat weed years ago and it did nothing. Same as I was expecting of Zyrexin. I think it did have me a little shaky and couldn’t sleep afterwards. That happens to me on bright moon nights and this is a bright moon night. I will use this product sparingly until I hear something really bad about it. I tried it only one time and to me it’s a keeper.

    • John is my middle name.

      John again. Zyrexin turned around and bit me! The first 4-5 times I used it no problem. Taking 1 or a half of 1 or taking 2. And it worked really well! Then last week I took 2 and man I was in for a mess. Shaking like a leaf and perspiring from head to toe. My hair was wet with sweat. I was cold but sweating profusely, soaked my socks and underwear. Saliva glands running like a spigot.. Vomited twice. Hiccups. Burping and bloated. Insomnia, awake all night. I actually was thinking should I go to the ER? Mind was racing. Hands shaking so violently I could not use a keyboard. And shivering.
      Yesterday I took a half to see how that would go. Same as above accept the shakes and sickness settled down in about 3 hours instead of 6-7 hours. I was nauseous but did not throw up but could have. So anyway. I have parted ways with Zyrexin for good. (it does work for me once I am over being sick) And now I am very leary (scared) to try any other brand of over the counter ed pill.

      • Anonymous

        It dose the same to me chills and sweating but it works really well as far as sex

  • Fuck zyrexin
    Jim (Verified Purchase)

    Sick. Shakes. Nausea. Sleeplessness and headache and no hard on

  • Mark

    very toxicated product, Causes severe headach, Dizyness, restlesness, runing noise, uring difficulties, and sleeples.
    This product has zero effects on ED problems, wasting money and severe suffering.

    • Colin Gresham

      How di you get rid of the uring pain???? Its been 12 hours and my private area is still constricted and causing pain in the urinary/bladder area kinda likenif been kicked in the nuts.

  • Zyrexin works really well
    Justin (Verified Purchase)

    I use zyrexin with great results . It sometimes causes a head ache, but so does viagra I’ve been through 15-20 bottles and it’s worked amazing everytime.

    • Mark

      you’re absulty wrong.
      this prduct causes severe suffering with zero effect on the probelm!

      • Charley

        Totally agree …shakes and nausea feel like crap. Better off with out it..waste of money

    • KEITH


      • Moon

        Worked great for me, had trouble sleeping afterward, but it fixed my ED problem. To each his own, I guess. None of the side effects you mention for me.

      • Colin Gresham

        Its been 12 hours. Nausea so severe i missed work the next day along with this pain like someone kickede in the balls. Literally 12 hours. How do you make this stop!?

  • Zyrexin- did not work for me
    AdaKB (Verified Purchase)

    I took 2 tabs first day, no impact at all. Then I took one on 2nd day, no impact either. Now Iam wondering if this is a bluff or worth continuing. Glad to know more from others who tried it.