Zyrexin is a blue pill made for men with difficulty achieving an erection. It uses a blend of natural ingredients to produce erections in men in less than an hour. Zyrexin is said to work “the very first time” a man uses it. Our research team decided to see what they could find out about Zyrexin and how well it works.
Although the product is widely sold, the research team was immediately concerned about the lack of scientific research that has been conducted using some of the ingredients. After that, they looked at potential side effects, the background of the makers, and what users of Zyrexin are saying. Finally, we wrapped all of the information into this concise report that brings you all the information you need.
Zyrexin is a supplement used to help men with erectile dysfunction achieve erections. It is made with a tuber vegetable used in traditional medicine as an aphrodisiac.
Zyrexin comes as a blue capsule and claims impressive results in just 35 minutes. The effect is supposed to last for 24 hours, which means that men should take it at any time of the day and still be ready for six hours later.
The makers of Zyrexin say that it is the only natural mixture to receive a patent in the United States for use as a male enhancement product. But, here’s the thing, having a patent doesn’t necessarily mean that a product works. It only says that the makers are protecting it from being copied by other companies.
What does science say about male enhancement products, in general?
Journal of Dietary Supplements – Overall, there’s concern that “adulterated and counterfeit male enhancement nutraceuticals and dietary supplements pose a real threat to the management of erectile dysfunction,” whether that be because of undeclared ingredients or mislabeling.
Journal of Addiction Research & Therapy – Despite the concerns over safety, “the use of herbal medicines continues to expand rapidly across the world and many people perceive usage of herbal medication as a safe and reliable way to improve health outcome.”
Zyrexin comes from a company called Superbalife International LLC. The company is based in Los Angeles, CA, and was founded in 2004. Superbalife makes nutraceuticals, which are products made from food sources that are supposed to have health benefits. They specialize in creating products specifically for men’s health.
The official website says that their products are all made in the United States in facilities inspected by the FDA. (Note: This does not mean the products themselves are FDA approved, only that the FDA makes sure their products are packaged correctly and the manufacturer follows safety rules.)
The company is not currently accredited by the Better Business Bureau (BBB). They have a B- rating, but no customer reviews.
Although there are no reviews of Superbalife International LLC on the BBB’s website, there are 8 complaints filed against the company. Three of the claims have to do with the company’s products or services. One is about billing issues, and the remaining charge is about delivery.
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The claims made about Zyrexin are impressive. If they prove true, Zyrexin might be the miracle pill that men are looking for. The Zyrexin claims include:
Works in as little as 35 minutes
The effects last for 24 hours
Works the first time it is used
No side effects
The official Zyrexin website states that the supplement contains a natural PDE-5 inhibitor. The official website does not provide an image of the label or even a complete list of ingredients. The only ingredient they disclose is something called Butea Superba. In reality, the supplement contains much more.
According to the product’s label, it contains a proprietary blend of herbs. Some of the ingredients in the combination are:
Xanthoparmelia Scabrosa Extract
Velvet Bean Extract
Butea Superba Extract
What is a PDE-5 Inhibitor?
The makers of Zyrexin say that Butea Superba is “the only natural PDE-5 inhibitor know [sic] in nature.” A PDE-5 inhibitor is a substance that stops cyclic guanosine monophosphate (cGMP) from breaking down. This allows blood vessels to remain dilated so that blood flows more smoothly. PDE-5 inhibitors work individually on type-5 phosphodiesterases, a cGMP form in the erectile tissue of the penis and the lungs, LiverTox claims.
Does Zyrexin Work?
Zyrexin promises outstanding results but whether it can deliver depends on whether there is clinical evidence to show the ingredients are active. The Zyrexin website doesn’t provide any links to studies using the supplement or any of its elements. However, our research team took the time to look into the science behind the ingredients. Here is some of what they found.
Yohimbe is a kind of tree that grows in parts of Africa. The tree’s bark contains yohimbine, which is used in a standardized form (yohimbine hydrochloride) to make prescription medications for erectile dysfunction.
Although yohimbine has been proven effective, there isn’t much research concerning Yohimbe used in dietary supplements. According to the National Center for Complementary and Integrative Health, nutritional supplements that contain Yohimbe vary in the amount of yohimbine in them. They also state, “Yohimbe sold as a dietary supplement may not work like the prescription medication that contains yohimbine.”
The amount of Yohimbe, or its active ingredient yohimbine, is not disclosed on the Zyrexin label. It is only listed as one of the ingredients in the proprietary blend. Therefore, there’s no way to know if there’s enough substance to have any effect.
Ginkgo, or Ginkgo Biloba, is an ancient tree species. It’s believed to be one of the oldest species of tree known to humankind. Although the seeds are poisonous, they were once given to royalty to treating senility.
According to MedicalNewsToday, ginkgo is thought to have health benefits because it contains flavonoids and terpenoids, both antioxidants. Antioxidants help to protect cells from free radicals.
Today, ginkgo extract made from the leaves of the tree is used in supplements to treat:
Leg pain due to narrowing arteries
According to the National Center for Complementary and Integrative Health, some studies have conducted using ginkgo to determine if it has health benefits and how it affects people. The studies have yielded “no conclusive evidence that ginkgo is helpful for any health condition.”
Velvet Bean Extract
The velvet bean, or Mucuna pruriens, is a legume that grows in Africa and Asia. It is often grown as a green manure crop because it fixes nitrogen in the soil. Also, it is used as fodder for livestock.
Velvet bean contains a substance called L-DOPA. People who are sensitive to L-DOPA may experience problems when taking the substance, such as nausea, vomiting, and cramping. They may even have an erratic heartbeat.
Some studies indicate velvet bean may be useful in treating fertility problems. A study published in a journal titled Fertility and Sterility suggests that velvet bean may improve sperm quality. The study involved 75 men with fertility problems and 75 men without fertility problems. The subjects were treated with mucuna pruriens. After the study, the researchers determined that taking the substance “regulates steroidogenesis and improves semen quality in infertile men.”
Butea Superba Extract
Butea Superba is the ingredient that the makers of Zyrexin give all the credit to on their website. It is a shrub that grows in Thailand, Vietnam, and India. The roots of the plant are tuberous and contain flavonoids and sterol compounds. In traditional medicine, Butea Superba is used by Thai men to boost sexual vigor.
Researchers published a study in the journal BJU International that showed the results of Butea Superba are inconsistent at best. An initial investigation showed positive effects on erectile dysfunction. However, a second double-blind study failed to duplicate the results. The researchers believed that the first batch of Butea Superba used had been mixed with a PDE-5 inhibitor. Their suspicions were later confirmed by the company that supplied the substance.
L-arginine is an amino acid that the body uses for proper blood flow. According to Examine, however, research shows that taking a supplement containing l-arginine may not have that same effect. Studies show that although l-arginine supplementation might activate nitric oxide, its effects are not reliable. This means that it is also not reliably useful for increasing blood flow.
Zyrexin Benefits and Results
Even though the makers of the supplement say that the Zyrexin benefit is men being able to achieve erections, our researchers didn’t find any clinical research to support that claim. Men who take Zyrexin may benefit from the antioxidants in a few ingredients, but that’s about it.
How to Take Zyrexin
The instructions for Zyrexin say that men should take one or two tablets about 45 minutes before sexual activity. Men should not take more than two tablets per day.
Potential Zyrexin Side Effects
The makers of Zyrexin say that the product has been “taken over 100 million times…without any reports of side effects.” The customer comments we read indicate that’s not the case. As with any supplement, some people may have no problems when taking it, but others might experience anything from mild side effects to ones that are concerning.
Some of the potential side effects of ginkgo are:
Also, the Mayo Clinic cautions against certain groups of people using supplements containing ginkgo, such as:
Women who are pregnant
Possible side effects are:
A painful erection that does not go away
As for Butea Superba, there just hasn’t been enough research conducted to determine if the substance is safe for human use.
Zyrexin Product Warnings
The Zyrexin label says that the product should not be used by anyone under 18 or by women who are pregnant or nursing.
Where to Buy
Where You Can Buy Zyrexin
Zyrexin is available through several retailers, including:
What Does Zyrexin Cost?
At the time of this review, Zyrexin is available at CVS for $21.79 for one bottle.
Those might sound like good deals until you find out that each bottle contains only ten pills.
Any Zyrexin Lawsuits?
The research team didn’t find any lawsuits associated with Zyrexin. However, the Canadian government did issue a “Foreign Product Alert” because it contains yohimbine, the active ingredient in Yohimbe. In Canada, yohimbine is a prescription drug and should not be taken without a doctor’s advice.
Is Zyrexin a Scam?
We hesitate to call Zyrexin a scam as there doesn’t appear to be any evidence of questionable business practices, usually the hallmark of fraud. However, we aren’t convinced that the supplement will help men with erectile dysfunction. Instead, it appears to be an overpriced herbal supplement with little effect.
There’s no shortage of male enhancement products on the market, and many claim to help men with erectile dysfunction. Some Zyrexin alternatives are:
“Consistent Product. Absolutely. NO PROBLEMS. Excellent Product. Would Re Order if I were able.”
“Did nothing for me. Not a good product.”
“Not to say it won’t work for somebody else but it didn’t work for me.”
Bottom Line on Zyrexin
Is it time to run to the store for a bottle of Zyrexin? We don’t think so. It’s true that there is evidence suggesting that some of the ingredients might improve fertility but not that they help with erectile dysfunction. The information our research team discovered left us with some concerns, such as:
Many customers reported having uncomfortable and even frightening side effects.
We found little evidence suggesting the ingredients in Zyrexin do anything to allow men to achieve erections.
Considering there are only ten pills in a bottle, the cost is quite high.
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