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GNC Mega Men Energy And Metabolism Review - 14 Things You Need to Know

Why is it that so few diet products are backed by science? Let’s find out if GNC Mega Men Energy and Metabolism is one of the good ones. There are people interested in this supplement, so we examined the ingredients, side effects, clinical research and quality of customer support. Additionally, we picked apart hundreds of consumer reviews and comments. We then refined and summarized to give you the info you need.

GNC Mega Men Energy And Metabolism can be purchased through their Official Site.

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What is GNC Mega Men Energy and Metabolism?

GNC Mega Men Energy and Metabolism is a vitamin supplement developed by General Nutrition Centers.

The supplement is promoted by the company as a calorie-burning multivitamin.

The all natural formula contains a blend of elements designed to enhance the body’s immune system functioning and support eye and overall health.

Other than vitamins and minerals, the main ingredients in GNC Mega Men’s Energy and Metabolism are caffeine, capsicum, black pepper extract and green tea extract, which are intended to increase metabolism and promote fat burning.

GNC provides no information on when their Mega Men’s Energy and Metabolism was first introduced. General Nutrition Centers has been producing their line of health products since 1935 and maintains a chain of stores that sell health-promotion products.

As of this writing, GNC is the world’s largest specialty retailer of nutritional products and holds a favorable rating with the Better Business Bureau.

Products Similar to GNC Mega Men Energy And Metabolism

GNC Mega Men Sport
Green Tea Triple Fat Burner
Advocare Spark

GNC Mega Men’s Energy and Metabolism Ingredients

The complete list of daily nutritional values for GNC Mega Men’s Energy and Metabolism supplements are:

  • Alpha-Lipoic Acid 25 mg
  • Astaxanthin (from Haematococcus pluvialis) 50 mcg
  • Beta-Cryptoxanthin 10 mcg
  • Biotin 300 mcg
  • Black pepper fruit extract (Piper nigrum) 300 mg
  • Boron (as Sodium Borate) 2 mg
  • Caffeine Anhydrous 100 mg
  • Calcium (as Calcium Carbonate and Calcium Ascorbate) 200 mg
  • Choline (as Choline Bitartrate) 10mg
  • Chromium (as Chromium Chloride 120 mcg
  • Copper (as Copper Sulfate) 2 mg
  • Eleuthero Root Powder (Eleutherococcus senticosus 40 mg
  • Energy and Metabolism Blend 150 mg
  • Folate 400 mg
  • Folic Acid 50 mg
  • Green Tea Extract (Camellia sinensis) 200 mg
  • Inositol 10 mg
  • Iodine (as Potassium Iodide) 150 mcg
  • Lutemax 2020 (as Lutein) 2 mg
  • Lycopene 950 mcg
  • Lycopene 1 mg
  • Magnesium 100 mg
  • Magnesium (as Magnesium Oxide) 100 mg
  • Manganese (as Manganese Sulfate) 2 mg
  • Molybdenum (as Sodium Molybdate) 75 mcg
  • Niacin (as Niacinamide & Niacin) 50 mg
  • Pantothenic Acid (as Calcium d-Pantothenate) 50 mg
  • Riboflavin (Vitamin B-2) 50 mg
  • Selenium (as L-Selenomethionine) 200 mcg
  • Silica (as Silicon Dioxide) 4 mg
  • Thiamin (Vitamin B-1 as Thiamin Mononitrate) 50 mg
  • Turmeric Root Extract (as Curcuma longa; standardized to Curcuminoids) 500 mcg
  • Vanadium (as Sodium Metavanadate) 10 mcg
  • Vitamin A 5000 IU with 50 percent as beta-Carotene and 50 percent Retinyl Acetate
  • Vitamin B-12 (as Cyanocobalamin) 50 mg
  • Vitamin B6 50 mg
  • Vitamin B-6 (as Pyridoxine Hydrochloride) 50 mg
  • Vitamin C (as Ascorbic Acid and Calcium Ascorbate) 300 mg
  • Vitamin D 1600 IU
  • Vitamin D (as Cholecalciferol D-3) 1600IU
  • Vitamin E 30 IU
  • Vitamin E (as Natural d-alpha Tocopheryl Acetate) 30IU
  • Vitamin K (as phytonadione) 80 mcg
  • Zeaxanthin 190 mcg
  • Zeaxanthin (as Zeaxanthin Isomers) 400 mcg
  • Zinc (as Zinc Oxide) 25 mg
GNC Mega Men Energy And Metabolism Customer Testimonials

Does GNC Mega Men’s Energy and Metabolism Work?

When trying to answer the question “Does the product Work?” there isn’t a clear-cut answer.

According to the GNC website, their vitamins have been “clinically studied.”

However, while the GNC Mega Men’s Energy and Metabolism formula does contain some compounds scientifically proven to help with weight reduction, there is no valid research to support the company’s weight-loss claims.

The claims GNC makes on their website are not substantiated by any known scientific studies or clinical trials that have examined the effects of this product directly.

The company also claims the product to be “physician endorsed,” however, GNC provides the same claim for all GNC products.

While GNC Mega Men’s Energy and Metabolism has a physician’s stamp of approval, the approval is provided by the General Nutrition Centers Medical Board, and not by doctors who aren’t affiliated with the General Nutrition Centers.

Reviews from users of GNC Mega Men Energy and Metabolism are mixed. Many users state they have seen an increase in energy and stamina while engaging in sports and during workouts and felt better on the whole later in the day while taking the Mega Men’s vitamins.

Some users also report significant weight reduction while taking the supplements.

On the other hand, many users report they saw no positive effects whatsoever, even when taking the upper dosage limits.

However, neither positive nor negative antidotal consumer reports of a product’s effectiveness should typically be taken as a substituent for peer-reviewed clinical research when answering; does the product work?

After a 2016 study of 28 long-term trials, researchers conclude that if a person makes appropriate lifestyle changes a quality weight-loss preparation can help increase the likelihood of achieving a meaningful fat loss, according to Weight Management and the International Journal of Behavioral Nutrition and Physical Activity.

GNC Mega Men Energy and Metabolism


GNC Mega Men’s Energy and Metabolism Benefits and Results

According to General Nutrition Centers, several of the pros of taking GNC Mega Men Energy and Metabolism is their formula helps to support colon and prostate health and increases the levels of crucial B vitamins.

Another claimed benefit is this product contains a combination of thermogenic enhancing compounds that are designed to increase calorie burning, boost mental sharpness and help control damage to cells caused by free radicals that are produced during vigorous exercise. Additionally, it has been shown that vitamin B5 aids in the production of hemoglobin.

While there does not appear to be any published studies to support GNC Mega Men’s Energy and Metabolism producing any of these benefits directly, some long-time users have given positive reports that the product does produce the result GNC claims.

Users providing anecdotal reports have stated that GNC Mega Men Energy and Metabolism has helped them to lose weight and feel more energized, both during workouts and throughout the day.

GNC Mega Men Energy and Metabolism

Details on GNC Mega Men’s Energy and Metabolism and Weight Loss

The compounds found in GNC Mega Men’s Energy and Metabolism and Weight Loss specific to aiding with weight reduction include:

Caffeine Anhydrous

Caffeine anhydrous is a stimulant as well as a diuretic. It is derived from several natural sources such as coffee beans, tea leaves, kola nuts, yerba mate plants, and guarana.

Clinical Research has shown that caffeine may help stimulate thermogenesis, the process of how the body generates heat and energy from the digestion of food.

As a dietary supplement in energy pills and weight-loss products, caffeine anhydrous is a dry powder.

Usually caffeine anhydrous is intended to reduce appetite, boost metabolism and energy levels while improving mental focus and athletic performance.

GNC Mega Men Energy and Metabolism

Green Tea

According to Current Pharmaceutical Designs, green tea is unfermented, unlike black and oolong tea varieties. Also known as Camellia sinensis, green tea also contains caffeine and antioxidants and is added to numerous diet supplements for its metabolism and immune system boosting properties.

A 2013 review of several studies found green tea helped to prevent several health-related issues.

Eleuthero Root Powder

More often referred to as ginseng, University of Maryland Medical Center claims that eleuthero root has been used for centuries to treat colds and flu symptoms.

According to the research, ginseng may also help improve athletic performance and increase muscle strength and endurance.

Eleuthero root is typically added to dietary supplements to aid in weight reductions by helping to reduce stress and boost immune system functioning.

While some clinical eleuthero root trials have recorded positive results, other studies did not find ginseng to produce these same results.

Other compounds found in GNC Mega Men’s Energy and Metabolism and Weight Loss with clinical studies that produced positive findings include:

GNC Mega Men's Energy and Metabolism


Compounds that fight cellular damage from environmental factors.

Black pepper fruit extract

Used to increase the absorption of drugs and supplements.


A mineral that aids in regulating levels of the hormone estrogen.

GNC Mega Men's Energy and Metabolism ingredients


A form of red pepper seed extract known to provide several health benefits.


A chemical similar to the B vitamins that are important for proper nervous system function.


Chemically similar to vitamins D and E and is believed to benefit brain function.

How to take GNC Mega Men's Energy and Metabolism

How to Use (Take) GNC Mega Men’s Energy and Metabolism

The recommended serving size of GNC Mega Men’s Energy and Metabolism formula is two caplets per day, taken with food.

The product comes in various size packages, including 45, 90 and 180 caplets and varies multipacks that will last for 30 to 90 days.

GNC Mega Men’s Energy and Metabolism Product Warnings

There are no direct warnings on the product label. However, there have been reports from users of various negative effects, including accelerated heart rate, diarrhea, nausea, shortness of breath and stomachache.

Side Effects

Is GNC Mega Men’s Energy and Metabolism Safe?

While there appear to be no known major dangers from taking GNC’s Mega Men’s Energy and Metabolism formula, the product does contain much time over the USDA daily dietary intake values for several nutrients.

For example, the formula contains over 16 times the recommended daily value of vitamin B1, over 15 times the recommended daily value of vitamin B2, 33 times the recommended amount of B5, over 25 times the recommended daily value of vitamin B6 and eight times the recommended amount of B12.

Because all cereals and breads are fortified with B vitamins, nutritional experts say there is no valid reason to take more than the daily allowance of B vitamins.

While there is no scientific evidence to prove that these levels of vitamin B are harmful, the higher levels probably won’t produce any positive effect. Still, there are some caveats.

In excess amounts, some B vitamins, namely B3 and B6, can lead to toxicity and too much folic acid can mask a vitamin B12 deficiency, according to Nutrients.

GNC Mega Men’s Energy and Metabolism Side Effects

In reviews, some users of GNC Mega Men Energy and Metabolism formula report several issues, including headache, diarrhea, nausea, and stomachache.

One of the major cons reported is many users who had completely cut caffeine out of their diets started experiencing an elevated heart rate and feeling lightheaded and jittery after they began taking the GNC formula.

A complete list of reported possible negative effects include:

  • Accelerated heart rate
  • Diarrhea
  • Dizziness
  • Headaches
  • Jitters
  • Muscle fatigue
  • Nausea
  • Shortness of breath
  • Stomachache

The GNC Mega Men’s formula contains the amino acid carnitine that aids in the metabolism of food.

However, excessive amounts of carnitine has been shown to cause diarrhea and GNC does not list the amount of carnitine in Mega Men, claiming it is part of their proprietary blend.

Rashes and Itching

This is a potential side effect of any supplement, and epically those with high levels of vitamin B12 are known to cause itching and rashes. Mega Men’s has over eight times the recommended daily value on B12.

Nausea and Upset Stomach

Taking GNC Mega Men may produce nausea. This is possibly linked to the high level of vitamin B5, also known pantothenic acid, present in this formula.

Headache and Dizziness

GNC Mega Men’s contains high levels of vitamin A, as beta-carotene, a nutrient that promotes healthy vision. However, even though this type of vitamin A is not dangerous, high doses can lead to dizziness and headaches.

Reduced Insulin Sensitivity

GNC Mega Men’s has levels of vitamin C that are five times higher than the daily recommended value, along with the high dose of vitamin E, may offset some of the effects of exercise and healthy eating.

Research done by the National Academy of Sciences has shown that in high doses vitamins C and E inhibited the enhancement in insulin sensitivity that is typically promoted during exercise.

Increased insulin sensitivity can help build muscle and burn fat, and impaired insulin sensitivity is one of the precursors to obesity.

GNC Mega Men’s Energy and Metabolism Lawsuits

In May of 2019, GNC was sued for deceptive and misleading advertising practices, according to court documents from the U.S. District Court.

The lawsuit specifically named GNC Men’s Prostate Formula, GNC Diabetic Support, GNC Preventative Nutrition Healthy Blood Pressure, and GNC Mega Men Healthy Testosterone, just to name a few.

Is GNC Mega Men’s Energy and Metabolism a Scam?

General Nutrition Centers has a long history of producing a wide range of health-related products. While there may be some legitimate cons and concerns with taking the formula, GNC’s Mega Men’s Energy and Metabolism should probably not be labeled anymore or less of a scam than any other supplement that claims to do things that have not been scientifically proven.

Where Can You Buy Mega Men’s Energy and Metabolism?

You can find GNC Mega Men’s Energy and Metabolism at GNC stores in most countries around the world, at many large retailers and online. Here are the main places where can you buy GNC Mega Men’s Energy and Metabolism:

  • GNC Retail outlets.
  • Large retailers that carry health-related products, such as Walmart, Kmart, Target, and Costco.
  • Online retailers like Walmart, Amazon and at GNC.com

The cost of GNC Mega Men’s Energy and Metabolism will vary depending on the supplier and quantity purchased. Prices will range from as little as $4.99 for 30 day supply to up to $50 for a 90 day supply of multi-packs. Typically, the amount will be less at larger retailers and online and cost more at smaller health stores.

On the official website, GNC Mega Men’s Energy and Metabolism costs $37.99.

GNC Mega Men’s Energy and Metabolism Alternatives

There are several alternatives to GNC’s Mega Men’s Energy and Metabolism formula. The main two alternative choices, in alphabetical order, are:

Advocare Spark

Advocare Spark is an energy drink in powder form, mixed with water. Advocare claims to have no added sugar and is a holistic blend of 21 vitamins, minerals, and nutrients that work together provide a natural source of energy and increase mental alertness.

Focus Factor

Focus Factor contains vitamins C, D, E, and B and claims to help with memory and concentration. Some of its key elements have shown promise in studies; resulting in weight loss.

What Users Are Saying

“Thanks to GNC for this great product. I started taking them last summer, since then I have lost 40 lbs! Apparently my metabolism needed a boost. And the energy helps me get out and exercise more. I definitely recommend this multivitamin to guys. There is also one for women so check that out too.”

“After years of using another brand, I decided to give GNC a chance. I have been trying it a for a few days and I have not noticed any improvement in my general energy which is quite interesting. I will give it another week to see what happens. The taste/flavor is weird and I don’t quite like it.”

“I took the pills after lunch and could not sleep because of the caffeine.”

GNC Mega Men Energy And Metabolism Ingredients
Bottom Line

The Bottom Line on GNC Mega Men Energy and Metabolism

Are you racing out to buy GNC Mega Man vitamins? Well, we like the low price and that we found a few positive comments, but we are skeptical about this one because the weight-loss claims are not supported by published clinical research. Plus, we’re concerned about it not working and customer reports of negative side effects.

If now is the last time you want to start a weight-loss journey, we suggest a clinically-proven program that combines personal interaction with the latest technology so you lose weight and keep it off.

Among the best weight-loss apps we’ve seen is Noom. The app provides a unique combination of human coaching, customized meal plans, expert resources and more to ensure you learn how to lose weight and how to keep it off, for good.

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GNC Mega Men Energy And Metabolism Review
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What are the side effects of GNC multivitamin?

Possible GNC Mega Men Energy and Metabolism side effects may include nausea, stomachache, diarrhea and headache. This is according to customer reviews.

What are the ingredients in GNC Mega Men Energy and Metabolism?

GNC Mega Men Energy and Metabolism ingredients are caffeine anhydrous, black pepper, capsicum seed, l-carnitine, taurine, l-methionine, l-glutamine, green tea, choline, inositol, alpha-lipoic acid, vanadium, astaxanthin, lycopene, zeaxanthin, lutemax 2020 lutein, boron, molybdenum, chromium, manganese, copper, selenium, zinc, magnesium, iodine, vitamin A, calcium, vitamin C, pantothenic acid, vitamin K, biotin, folic acid, vitamin D, niacin, vitamin B12, riboflavin, vitamin B6, vitamin E, thiamin and silica.

Does GNC Mega Men Energy and Metabolism work?

GNC Mega Men Energy and Metabolism contains green tea and caffeine; both shown to boost metabolism. These ingredients have been clinically-tested and may help with weight-loss, but the benefits of the two are not linked to this product.

How much does GNC multivitamin cost?

The cost of GNC Mega Men Energy and Metabolism is $22.99.

How should I take GNC Mega Men Energy and Metabolism?

The directions say to take one packet daily with food. A box will last for 30 days.

Where can I buy GNC Mega Men Energy And Metabolism?

GNC Mega Men Energy And Metabolism can be purchased using their Official Site.

Can women use GNC Mega Men Energy and Metabolism?

Yes, but it’s not recommended. This product is formulated for men.

Is there an age cut-off for GNC Mega Men vitamins?

No, as long as you are 18 or older, you can take this product.

18 GNC Mega Men Energy And Metabolism Reviews

  • Francisco

    Can these cause insomnia?

    • Anna (Editor)

      Hi Francisco. All users are different and can experience different effects; if you begin to have insomnia, consult with your physician before continuing with this product.

  • when i will take the best results

    I would like to know is it a time release product, and if so when should I take it for best results?

    • Your Name

      This product is excellent. I am chef and i used to work 7 days a week on cruise ships, trust me, these supplements kept me energized all day and i would sleep soundly at night. They also keep you mentally alert. In my job i would start to get tired around 3pm but when i take 2 of these pills (anytime before midday but not too early) i would be happy and enthusiastic all day. 3 years now and no side effects- never felt better.

    • Joshua R Akramoff

      Yes they are time released, thank God or they would tear your stomach to pieces.

  • scott

    I just finished emailing back and forth over the fact that GNC just drastically changed this product recently. They have removed insitol, carnitine, taurine, methionine and glutimine. They added tumeric root extract and eleuthero root powder. When i opened a container that i just purchased due to running out. I noticed a huge difference in the caplet size. I went to my kitchen trash can and pulled out the old container. The old container is much larger. I asked why GNC changed the product and I asked what they removed to make the caplet smaller. As you can imagine I haven got a direct answer. To paraphrase i was told that the product was improved based on what their customers wanted. LOL! The biggest thing to me was they are charging the same price after removing ingredients. The expiration dates caught my eye too. The old version of this product was dated 5/18 and the new one was dated 9/18? So what happened in 4 months time? Was the old product dangerous? Was it ineffective? Why didnt they let their customers know they changed the product? GNC didnt offer a decent explanation. They basicly said if you aren’t satisfied get your money back.

  • Ed,

    I’ve been taking the GNC Mega Men Energy And Metabolism for about 1 year and was fine until they changed it up, pills are smaller and doesn’t work as well .

    • Maribel (Editor)

      Oh no, that’s not good. Since you’re dissatisfied with their change, perhaps you could sample Dietspotlight Burn and see if it works better for you.

  • Kevin

    I’ve been taking this for about a week now. I did not buy it for weight loss specifically. I was looking for a multivitamin to get me through the day without the afternoon drag. I also have been losing weight, and was hoping this would assist with those last few hard to shed pounds. I have not had any of the side affects mentioned here. The only thing out of the ordinary was my body getting used to the extra B2. The first couple days my urine was neon yellow. But now it seems my body is metabolising it better, as this has passed. I’d say the vitamin does exactly what it claims. I have all day energy and have noticed my metabolism ramping up, which is great!

  • Your Name JOHN ISHAK

    Hi im from Ontario Canada I just bought a box of 90 capsules, $ 33.00, to day October the 11th, 2016 I have been taken my third pill, So Far so Good, I am Living the Dream. Feel Lots Energy, Not Sleepy. Let’s cross our fingers and experience referent. Regards John Ishak

  • Scotty

    I’ve been taking this plan for about a month. This morning for the second time I’ve experienced flushing and a rash that starts at my face/head and then moves down my neck and arms. Not a great feeling that comes on suddenly. I’ve been trying to keep this to almost an every other day regimen; but have been mostly happy with results.

  • Boogie man

    I notice the difference between Mega Men Sport and Mega Men Energy Metabolism. Energy does speed up you metabolism and I’ve managed to lose a free pounds and keep it off. On the negative side it does speed your heart rate up and make you feel jittery. It doesn’t happen everyday. Mega Men Sport is food for recovery and keeping muscle on.

  • Steve

    GNC Mega Men Energy And Metabolism is giving me a lot of energy, but I am bloated and gaining weight. I like the increased energy but, I do not like the feeling of being bloated, putting on added weight, and fighting additional chronic pain after I do too much daily.

    • Bobby

      Steve is absolutely correct, the weight gain is unbelievable but the energy is great not worth the time if you’re trying to lose weight great energy but I don’t need the weight gain

  • Bob

    I have been using Mega Men Energy and Metabolism for 6 weeks now – I have lost 12-14 lbs but I am also using twice daily apple cider vinegar and lemon juice (1 tbsp. each) mixed in 8 oz of water……………….with E&M I HAVE felt like my body temp rises but also I have more energy and am slimmer as well with the weight loss.

  • Tried Different Items This Works
    anthony (Verified Purchase)

    I’ve tried different vitamins , I realized that this one works for me.

  • Jerry

    Good products no complaints

    • kevin

      I love this product and having been using it for 3 years. It gives you two energy boosts usually around 3to 4 hours after poppin the pill. The energy boost make me feel near super human but they last around an hour or so. I think in conjunction with a proper diet this is the perfect product.