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Protandim Review - Does This Oxidative Stress Reducer Work?

By Summer Banks on Nov 15, 2016
Protandim Review

Don’t laugh, but well over 50% of diet products simply don’t work. So what about Protandim? Well, we wrote one of our in-depth reviews, scrutinizing the side effects, ingredients, clinical studies and level of customer care. Furthermore, we took a look at dozens of user comments and dieter responses from all over the web. At this point we condensed and summarized to give you with the facts you need.

EDITOR'S TIP:

What is Protandim?

First off, Protandim is a dietary supplement that is intended to reduce oxidative stress through “Nrf2 activation.” The ingredients used in Protandim are milk thistle extract, green tea extract, bacopa extract, turmeric extract and ashwagandha root. [1] According to the official website, this product can lower stress levels by 40 percent in only 30 days. This in turn helps the body function more efficiently, combats signs of aging and reduces damage from free radicals. You should take it with food. [2]

Protandim is made by LifeVantage and it has been available since 2003. This supplement contains natural ingredients and there is convenient contact information on the company website. Furthermore, it’s easy to purchase through the main website, but read on…

Customer Complaints – “Concerning?”

The first thing we address with Protandim ingredients is the number of customer complaints. According to our Research Editor, “There are quite a few user experiences that are not exactly positive. This is a red flag that should not be ignored.” [3]

One customer commented, “This product did nothing for me whatsoever! Don’t buy!”

“Waste of money! My doctor even told me to stop using it,” said another user.

Results with Protandim – “Lacking”

One doctor commented, “Their product is extremely overrated and they have NO positive human studies whatsoever. The components in Protandim can be acquired on Amazon for a tiny fraction of the cost of what it’s costing now.” [4]

Another person stated, “I do not recommended the use of Protandim. There is no evidence that it provides a health benefit to humans.”

Our research has proven that if there is some particular part of a weight-loss supplement or diet program that is especially burdensome (too many customer complaints, lack of results, high cost) the likelihood of long-term success is quite minimal. So, if Protandim does fail to produce measurable effects in a lot of people, this could be problematic. [5]

The Science – “Valid?”

Although “science” is mentioned for Protandim on the official website, there are no actual clinical trials involving humans, which makes it difficult to determine how well this product actually works. At DietSpotlight, we prefer to see documented research regarding the product and how well it works on people. [6][7]

The Bottom Line – Does Protandim Work?

Alright, are we out there looking for some Protandim? Well, we like that it contains natural ingredients and a lot of information is presented on the company website. But we have some reservations because no solid science is provided that involves human clinical trials. Also, we’re concerned about the customer complaints and negative comments posted online.[8]

If you’d like to drop more weight, then we encourage you to select a product that is supported by lots of positive user feedback, backed by solid clinical research and sells at a reasonable price.

Among the best products we’ve seen in 2016 is one called Leptigen. Its formula is a proprietary blend of four powerful ingredients, which has been shown in documented scientific research to help accelerate fat loss and ignite metabolism. Also, we can’t find any complaints of harmful side effects and customer comments found online indicate people are seeing great results.

The makers of Leptigen are so certain of their product they’re offering a Special Trial Offer, which is a good sign.

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About the Author:

Summer Banks is an ISSA-Certified Fitness Nutrition Specialist and has reviewed over 2000 diet products. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

How Does Protandim Compare?

Previous Protandim Review (Updated April 9, 2014):

Protandim: What You Should Know

At first glance, Protandim does not look like a diet product. The product description talks about reducing oxidative stress, or stress caused by free radicals. This means the supplement contains antioxidants, but there is one proven weight loss ingredient in the formula, so there is some good to be had out of taking this product with an exercise program and healthy meal plan. Pertaining to meal plans, meal supplements with protein, green coffee bean and other ingredients, can be found in Metagenics which can be conducive to healthy weight loss. The complete Protandim ingredient list is available on the official website and there is mention of clinical studies. This does not mean clinical studies have been completed directly on Protandim, but we'll see.

Protandim Ingredients

Ingredients:
  • Milk Thistle Extract
  • Bacopa Extract
  • Ashwagandha Root
  • Green Tea Extract
  • Turmeric Extract

Features of Protandim

The two ingredients we are most interested in from a diet point of view are green tea and turmeric. Green tea is clinically proven to boost metabolism, even if the caffeine in green tea is taken out of the equation. The EGCG present in green tea boosts metabolism in addition to the added benefits of caffeine. Turmeric recently hit the weight loss market with some pretty impressive preliminary studies. In the studies, participants who took turmeric lost more weight than participants who did not. Additional large-scale studies replicating this effect are needed before the ingredient is considered clinically proven. Although weight loss is an indicator for change in health benefits, one should consider the growth of joint health, immune system support and nutrients infused with vitamins and minerals; Natures Balance is one for consideration. While researching the Protandim Ingredients, we found something odd. Under the clinical proof tab we found the clinical proof we'd hoped for, but the study has nothing to do with weight loss. Protandim is clinically proven to reduce oxidative stress. In other words, the supplement works as an antioxidant, which can impact overall health, but not weight loss directly. Similarly, Catalyst doesn't intentionally promote weight loss, but it does help muscle growth and recovery using amino acids, both conducive to health and wellness for the long-term.

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Advantages of Taking Protandim

  • Proven to have antioxidant effects on the body.
  • May reduce oxidative stress by 40%.
  • Clinical studies were completed on Protandim, not just the ingredients.
  • Green tea and turmeric are proven to boost metabolism and weight loss.

Disadvantages of Taking Protandim

  • Protandim is not a weight loss supplement.
  • No detailed information on ingredient amounts.
  • The only customer reviews available on the website are in video format.

Conclusion

Protandim is quite an impressive supplement in its given category, but that category is not weight loss. While green tea and turmeric may be beneficial for weight loss, we have no idea how much of each ingredient is included in the supplement. The recall that turned up during our research on Protandim Side Effects also concern us. It is unlikely that there is enough of either to boost metabolism since this supplement is created as an antioxidant not a fat burner. There should be no negative interactions between this supplement and other fat burners, but it is best to contact your physician before taking Protandim.

Protandim Questions & Answers:

We narrowed down hundreds of user reviews about Protandim and created this helpful FAQ.

What are the side effects of Protandim?

Some potential Protandim side effects, reported by customers, include allergic reactions, vomiting, diarrhea, stomach ache, headache and rash.

What are the ingredients in Protandim?

Protandim ingredients include milk thistle, bacopa extract, ashwagandha, green tea and turmeric.

Does Protandim work?

There a several studies listed on the Protandim website. What we noticed after reviewing the research, were the findings didn’t relate to weight-loss, only oxidative stress. Although the supplement contains green tea, an ingredient linked to weight-management, it doesn’t point toward this formula.

You may want to take a closer look at Protandim, what you want out of a dietary supplement and thinking about a supplement like Leptigen, which consists of some clinically-tested ingredients.

How much does Protandim cost?

Protandim costs $50 for a 30-day supply. If you sign up for the auto-ship, the cost is $40.

How should I take Protandim?

You should take one Protandim capsule per day. One bottle lasts a month.

Can I take Protandim if I have a health condition?

Women who are pregnant or nursing, those with health conditions, anyone under 18 years of age or people taking prescription medications should contact a healthcare professional prior to using a dietary supplement of any kind, including Protandim.

What do users like about Protandim?

Some users liked the low price tag of Protandim.

What do users NOT like about Protandim?

Not losing weight was something Protandim users didn’t like.

How do I contact the Protandim customer service department?

You can connect with the Protandim customer service department by calling 1-866-460-7241, emailing a representative at customerservice@lifevantage.com or by mailing correspondence to LifeVantage Corporation 9785 S. Monroe St. Suite 300 Sandy, UT 84070.

Does Protandim contain caffeine?

No, Protandim doesn’t contain caffeine, but the green tea could possibly act as a stimulant.

What is NrF2 in Protandim?

NrF2 in Protandim is a protein supposedly stimulating enzymes to reduce the effects of free radicals.

Why was Protandim pulled from the shelves?

Protandim was pulled from the shelves in 2012 because the company found some lots possibly includes metal fragments.

Does Protandim come with a guarantee?

Protandim does come with a guarantee. You have 30 days to return the supplement for a full refund.

Do you know of any special deals or discounts on Protandim?

There’s no mention of deals or discounts on the official Protandim website. However, our readers have been going wild over the last few months taking advantage of Leptigen’s Special Trial Offer, which is simply the cost of shipping and handling. Click here to give it a try.

Protandim Side Effects:

Protandim is a widely-used product for health and weight-loss. While the weight-loss results are mixed, most experiences are free of negative consequences. However, there are some rare side effects to be aware of.

Stomach Pain

Stomach pain can make it hard to get through the day. In milder cases, it’s a general unease in your stomach area. When it becomes severe, stomach pain can be an acute stabbing sensation. Often, stomach pain is accompanied by symptoms like gas, bloating, nausea, fever, and sweating.

What causes stomach pain?

Stomach pain has many possible causes. Many cases stem from indigestion and food intolerance. It’s also possible to experience abdominal pain as a result of pelvic inflammatory disease or stomach virus. [1]

Diarrhea

A bad case of the “the runs” can be extremely uncomfortable. Having to go to the bathroom every few minutes to pass a watery stool leaves you exhausted. Your rectum is prone to burning and rash. Also, because diarrhea expels so much liquid, you’re at risk of dehydration. If you suffer from diarrhea, be sure to drink plenty of fluids.

What causes diarrhea?

Most cases of diarrhea are the direct result of stomach viruses and bacteria. These infect your body when you eat something spoiled. It may also be that your body has an intolerance or allergy to something you ate. Or you may be suffering from irritable bowel syndrome.

Vomiting

Vomiting is often accompanied and preceded by nausea and stomach ache. It can consist of various sessions and come and go throughout the day. Vomiting leaves you with a burning sensation in your throat. It can also lead to dehydration and malnutrition. Prolonged vomiting is cause for concern and may require the attention of a doctor.

What causes vomiting?

One of the top causes of vomiting is food poisoning. Be careful with what you consume. Always make sure food isn’t expired and that it doesn’t contain ingredients to which you’re allergic. Vomiting can also be a result of conditions like migraine, appendicitis, concussion, hyperthyroidism, and fever. [2]

Headaches

A headache can be very stressful. Depending on the severity of the pain, you may feel dizzy and weak. Headaches make it hard to focus and concentrate.

What causes headaches?

Most headaches are not cause for concern. They’re provoked by stress, hunger, or tiredness. They go away after a few hours with rest. Some headaches may be indicative of an underlying illness. Glauccoma, high blood pressure, and stroke are known to cause headaches. Seek a doctor’s help if you experience regular headaches.

Protandim is normally safe to use. Everyone reacts differently to supplements. To be on the safe side, talk with your doctor about how Protandim’s ingredients may influence your health.

We dug deep into the Protandim ingredients to give you the important specifics you need.

Milk Thistle Extract

Also called silybum marianum, this is an herb that has been used in traditional remedies for centuries. It’s sometimes used to treat mushroom poisoning, liver disease, viral hepatitis, and even cancer.

What is it Supposed to Do?

Milk thistle contains antioxidants that help ward off free radicals and reduce inflammation. It’s often used in cleansing supplements to help flush dangerous toxins and impurities out of the body.

Clinical Research

There is really not much solid research that supports the claims pertaining to milk thistle. However, according to the Mayo Clinic, “Medical research does suggest that milk thistle, combined with traditional treatment, can improve diabetes. Studies have shown a decrease in blood sugar levels and an improvement in cholesterol in people with type 2 diabetes.” [1]

Clinical testing is important when it comes to choosing the best diet supplement for your needs and fitness goals. You may want to take a look at a formula like Leptigen. This product contains key ingredients that have been scientifically researched.

Bacopa Extract

Also referred to as bacopa monniera, this is a plant that is often used in Ayurvedic medicine. It has been claimed to treat epilepsy, asthma, irritable bowel syndrome, anxiety, joint pains, body aches and Alzheimer’s.

What is it Supposed to Do?

You will find that bacopa extract is used in many diet supplements. It’s typically claimed to improve memory and focus, while boosting sexual performance. However, there does not appear to be a direct link to weight-loss.

Clinical Research

According to PubMed.gov, “There is some evidence to suggest that Bacopa improves memory free recall with evidence for enhancement in other cognitive abilities currently lacking.”

Ashwagandha Root

The berries and roots of the ashwagandha plant are often used to make medicine. More specifically, this herb has been used to treat arthritis, anxiety, diabetes, high cholesterol levels, ADHD, liver problems and stress. It’s also found in some over-the-counter supplements.

What is it Supposed to Do?

Often ashwagandha root is claimed to reduce stress levels, which in turn lowers cortisol, the hormone that leads to weight gain and belly fat. It contains lactones and antioxidant steroidal alkaloids. This herb may also help lower blood sugar levels. [2]

Clinical Research

Some research has been conducted with ashwagandha root. For instance, WebMD states, “There’s some early evidence that ashwagandha affects the immune system and helps reduce swelling, from both arthritis and fluid retention. However, the practical benefits and risks for people aren’t clear yet.”

Is There Anything Out There That We Think TRULY Works?

There is one supplement that caught our eye. Leptigen, which is formulated with clinically tested ingredients, comes across as a solid option. Each and every customer can take complete advantage of a Special Trial Offer, that’s currently available. Click here to give it a try today.

34 User Reviews About Protandim

Leave comments below (moderated by Leptigen)
  • 1
    Iwa

    The first 3 weeks I felt the extended energy where I could come home and play with my children and then like by the second month..I don’t feel other working no more..is that normal

    [Reply]

    Anna (Editor)

    Hello. All users are different and can experience different results.

    [Reply]

  • 2
    CS

    Protandim has helped me tremendously….I’ll never be without it. It has helped me sleep better, my mind clearer, depression, arthritis pain is gone, etc.

    [Reply]

  • 3
    Julie

    ibe been taking protandim for three months. I have had chronic colitis and irritable bowel syndrome with chronic constipation
    It’s the first time in my life that I have gone to the bathroom every day
    I could right away that my memory was better and my asthma was better
    At first my stomach was upset so I broke in half for one week then increased to one
    No more bloating
    Rarely any discomfort and no constipation
    My doctor was talking surgery but I’m feeling so much better so I’m not
    I also drink alkaline antioxidant water

    [Reply]

  • 4
    JD

    7 years ago, I viewed an ABC investigative report on Protandim and a PBS Healthquest segment on it which gave me enough information for me to know that I wanted to take it. My family and I have been taking it daily for 7 years. My husband is in medicine and swears by it. He doesn’t tell patients about it because that is improper. Those physicians who say don’t take it, don’t know anything about it, but if you ask them if I can reduce my oxidative stress levels by 40% would it help me? They would not hesitate to say yes. Physicians will agree that oxidative stress & inflammation is at the root cause of most disease and illness.

    That’s why we take it. We want to PREVENT issues.

    It’s simple to take 1 a day right along with our prescription medications (that have been dramatically reduced since we began it). My children (2 of whom are autistic) have seen great benefits in concentration, calm and focus). They are now ages 22, 18, and 16. It is not a “cure all” but a nutritional supplement that stimulates your body’s healing pathways (in layman’s terms).

    It’s a patented herbal formula that seems to work. We will always continue taking it. There’s no doubt we have gotten great benefit.

    [Reply]

  • 5
    Sherry

    Protandim is wonderful because it reduces oxidative stress (read the research studies on PubMed). You may not necessarily feel better , or worse…. Just know what it does and you will find it useful .

    [Reply]

  • 6
    Ramona

    I took Protandim for about a month and felt pretty good. I seemd to sleep better and woke up refreshed. I stopped taking it for about a month and then took it again. The first day I took it (with food and drank lots of water), I got very sick. So sick that I had to leave work as I was vomiting and had diarrhea. I then took it again about a week later and had the same problem. If that is the detox, that is crazy as I shouldn’t be having everything empty out of my system. I really can’t deal with how sick it has made me and I have tossed what I had left. I think I will work on eating healthy and taking regulated vitamin supplements.

    [Reply]

  • 7
    GJ Beauchamp

    I’ve have been taking Protandim for 4 years. I was diagnosed with TAYSACHS in 1989. It has changed my life for the better. Praise GOD!

    [Reply]

  • 8
    Colien

    I have been taking protandim for 4 months and although I feel better and can concentrate much better, I have had urinary tract infections twice in the past 3 months. I have had UTI’s in the past, however only once every 2 – 5 years. Is there an ingredient that can cause this?

    [Reply]

    Jessica (Editor)

    Hi! For detailed product and usage instructions, please refer to the Protandim official website for more information.

    [Reply]

  • 9
    Jessica (Editor)

    Hello. All users are different and can experience different side effects, but we have noticed that users have experienced somewhat similar side effects. Please make sure to consult with your physician before continuing taking this product if you are still having side effects.

    [Reply]

  • 10
    Chamie Thornton

    I have been taking protandim for 2 days now. I have been experiencing headaches.Is this a side effect?

    [Reply]

    Darren

    The first thing you will notice from taking protandim is a detoxifying effect which could include headaches.

    [Reply]

  • 11
    Oscar

    I’m a true skeptic , but after using product and seeing the results in my mother and in myself we will continue using Protandim and I will recommend to others , it’s not a diet pill so if ur trying to lose weight it’s not going to happen , 2 months among my mom became very weak , falling constintly , couldn’t even hold up a coffee cup or do anything she use to do with ease , I was desperate doctor couldn’t find what was wrong with her , blood work , x-rays , ultrasounds , Mri and so on and nothing everything negative , I was told about Protandim nrf2 from my best friend , we have been on it for about a month and seeing her improvement is beyond words , can’t wait to start taking Protandim nrf1 and nrf2 , this product is legit , if u are going to try it do it for 30 days at least , I’m on day 26 and feel good

    [Reply]

  • 12
    Your NameLoretta

    I take norco for back pain after 2fusions also take valium &high b/p meds.how will it effect me while on these meds?I purchased it but don’t know if I will have bad reactions? Living in chronic pain for 4years. I bought the product to help gain my energy back and heal my cells due to all the stress in my life.So do I stay on my normal meds while taking Protandim? Please answer my question,I have had bad reactions for chronic pain meds like, lyrica,cymbalta,gabapenten.I also have short term memory loss from those chronic pain meds.Help me take this product correctly.

    [Reply]

    Adrian (Editor)

    Hi! Because you take these medications, please make sure to consult with your physician before starting a new weight-loss program or product

    [Reply]

  • 13
    Rosemary Rickard

    I took Protandim for seven days straight. I watched a you tube video of a guy that swore up and down that Protandim lowered his glucose levels for his type 2 diabetes. I tried it for 7 days and all I got was burning and irritation in my GI tract and my glucose levels went up each day I took it with no change in my low carb diet. I gave discontinued taking Protandim and am returning the product.

    [Reply]

    Oscar

    Are u serious 7 days smh , take it for 30 days then give ur comment and did u take that without food ? I’ve never heard if that problem and I know easily over 30 people that take it and that have good results

    [Reply]

  • 14
    Your Angela Name

    Iv been taking protandim for 5 days thinking they get better as they got into my system and Iv felt dreadful I’m not sleeping there making me feel sick and without energy I keep getting hot flushes and headache I felt so badly today I came home and went to bed I won’t be taking them again…

    [Reply]

    Your Name

    Are these symptoms above normal ?? Please can you tel me why this as happened taking Protandim.

    [Reply]

    Jinessa

    Hi there! Sounds like you were having some detox symptoms. Protandim has that effect on our body. Be sure to drink at least half of your body weight in oz. and possibly cut your pill in half until this subsides.

    [Reply]

    Pat Armstrong

    I too felt nauseous, and tired, having had to detox for liver issues, I knew that’s what was happening. It has to take place before your system can be synergized with a new product. Take it for 30 days before you complain. Take it with food, and drink plenty of water…

    [Reply]

    Darren

    As with any product that cleans out your system it WILL have a detoxifying effect. Keep drinking lots of water, 2+ liters a day. The sicker you are the more junk that needs to come out of your body. When I first starting taking Protandim I felt like I had the flu for about 4 days. Chest congestion, aching body, sniffles, diarrhea, tired, dragging my arse. I just kept taking them and after about 10 days I felt awesome. Like I needed to go paint the house or run a couple blocks. That was over 3 years ago and today I feel amazing. I used to get the flu every winter, but Not anymore. Dont let the naysayers and Big Pharma Spin Doctors take away your wellness. Keep On Keepin On, You can feel great TOO!!

    [Reply]

  • 15
    Marlene

    Love the product am on my 3rd bottle but have concerns. Why am I putting on weight. I have gained 8lbs. The first bottle I lost about 6 lbs, u now have put all back on and more. Please respond.
    Marlene Krueger

    [Reply]

    Your Nameloretta

    Tell us your my concerns are I take Norco &valium,my concern is how will it interact with my meds,also take meds for high b/p.how do I handle my meds with it?

    [Reply]

    Adrian (Editor)

    Hi! Because you take these medications, please make sure to consult with your physician before starting a new weight-loss program or product

    [Reply]

  • 16
    bev billingsley

    Can you tell me if ubiquinol can be taken along with protandim. I can’t seem to get an answer from anyone. Thank you.

    [Reply]

    Mandy Haney

    Ask your doctor that would be best but you may need to give him so info on protandim. Protandim I do know can’t be taken afterror a kidney transplant because the transplant drugs start to fade from your body producing it’s own antioxidants this I believe over rides alot of prescriptions best to speck with your doctor and have him research protandim but I would after knowing what protandim had done for me and my loved ones

    [Reply]

  • 17
    Marjorie La///bell

    could not find price

    [Reply]

  • 18
    Earl D Sorensen

    I didn’t know that the product has caffeine in it. I’m not suppose to use caffeine!! Is their tantium in this product also???

    [Reply]

    Wayne Wood

    It has no caffeine in it. Where did you hear that?

    [Reply]

    Your Name

    Green tea has caffeine.

    [Reply]

    Kathy pennell

    Green tea has caffeine. Turmeric is a blood thinner. I have tried Protandim twice. Took half a pill to start still got stomach discomfort and other gastro issues.

    [Reply]

    Your Name

    When I first started I was having gastro problems but I continued taking anyway because I notice I felt better after all the detox symptoms

    [Reply]

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