Updated: 11/24/2015 - Sponsored by Leptigen

Protandim Review - Does This Health Supplement Actually Work? Are customer complaints and lack of real results deal breakers?

Editor's Review: 3.5 / 5.0

Don’t laugh, but well over 50% of diet products simply don’t work. So what about Protandim? Well, we wrote one of our in-depth reviews, scrutinizing the side effects, ingredients, clinical studies and level of customer care. Furthermore, we took a look at dozens of user comments and dieter responses from all over the web. At this point we condensed all of the data we collected to provide you with the facts you need.

EDITOR'S TIP: Combine Protandim with a proven fat burner such as Leptigen for better results.

What You Need To Know

Protandim is a dietary supplement that is intended to reduce oxidative stress through “Nrf2 activation.” According to the official website, this product can lower stress levels by 40 percent in only 30 days. This in turn helps the body function more efficiently, combats signs of aging and reduces damage from free radicals. The ingredients used in Protandim are as follows; Milk Thistle Extract, Green Tea Extract, Bacopa Extract, Turmeric Extract and Ashwagandha Root. This supplement is available online for $50 (30 caplets). Protandim is directed to be taken daily with food.

Protandim is made by LifeVantage and it has been available since 2003. This supplement contains natural ingredients and there is convenient contact information provided on the company website. Furthermore, it’s easy to purchase Protandim through the main website, but read on…

Customer Complaints – Concerning?

According to our Research Editor, “There are quite a few user complaints posted online for Protandim. This is a red flag that should not be ignored.”

One customer commented, “This product did nothing for me whatsoever! Don’t buy!”

“Waste of money! My doctor even told me to stop using it,” said another user.

Scroll below for one of the best products we’ve seen in 2015.

Lack of Real Results!

One doctor commented, “I am a physician who is involved with a company that has far more scientifically valid products than Protandim. Over a period of a couple of years, the “leadership” at Lifevantage completely jerked our company around and told us about an imminent deal, etc. I can’t imagine a more unethical dishonest company. Their product is extremely overrated and they have NO positive human studies whatsoever. The components in Protandim can be acquired on Amazon for a tiny fraction of the cost of what it’s costing now. I would avoid any dealings with this extremely low class company who trades in BAD FAITH.”

Another person stated, “I do not recommended the use of Protandim. There is no evidence that it provides a health benefit to humans.”

Our research has proven that if there is some particular part of a weight loss supplement or diet program that is especially burdensome (too many customer complaints, lack of real results, high cost) the likelihood of long-term success is quite minimal. So, if Protandim does fail to produce real results in a lot of people, this could be problematic.

The Science – Solid?

Although “science” is mentioned for Protandim on the official website, there are no actual clinical trials involving humans, which makes it difficult to determine how well this product actually works. At DietSpotlight, we prefer to see documented clinical research regarding the product and how well it works on people.

The Bottom Line: Does Protandim Work?

Now the moment you’ve been waiting for: our bottom line on Protandim. Well, we like that Protandim contains natural ingredients and a lot of information is presented on the company website. But we have some reservations about this supplement because no solid science is provided that involves human clinical trials. Also, we’re concerned about the customer complaints and negative comments posted online.

If you’d like to drop more weight, then we encourage you to select a product that is supported by lots of positive user feedback, is backed by solid clinical research and sells at a reasonable price.

Among the best products we’ve seen in 2015 is one called Leptigen. Its formula is a proprietary blend of four powerful ingredients, which have been shown in documented scientific research to help accelerate fat loss and ignite metabolism. Also, we can’t find any complaints of harmful side effects and customer comments found online indicate people are seeing great results.

The makers of Leptigen are so certain of their product they’re offering a Special Trial Offer, which is a good sign.

Learn More About Leptigen »
GD Star Rating

How Does Protandim Compare?

Previous Protandim Review (Updated April 9, 2014):

What You Should Know

Click Here To See Our Highest Rated Review

At first glance, Protandim does not look like a diet product. The product description talks about reducing oxidative stress, or stress caused by free radicals. This means the supplement contains antioxidants, but there is one proven weight loss ingredient in the formula, so there is some good to be had out of taking this product with an exercise program and healthy meal plan. The complete ingredient list is available on the official website and there is mention of clinical studies. This does not mean clinical studies have been completed directly on Protandim, but we'll see.

List of Ingredients

  • Milk Thistle Extract
  • Bacopa Extract
  • Ashwagandha Root
  • Green Tea Extract
  • Turmeric Extract

Product Features

The two ingredients we are most interested in from a diet point of view are green tea and turmeric. Green tea is clinically proven to boost metabolism, even if the caffeine in green tea is taken out of the equation. The EGCG present in green tea boosts metabolism in addition to the added benefits of caffeine. Turmeric recently hit the weight loss market with some pretty impressive preliminary studies. In the studies, participants who took turmeric lost more weight than participants who did not. Additional large-scale studies replicating this effect are needed before the ingredient is considered clinically proven. Under the clinical proof tab we found the clinical proof we'd hoped for, but the study has nothing to do with weight loss. Protandim is clinically proven to reduce oxidative stress. In other words, the supplement works as an antioxidant, which can impact overall health, but not weight loss directly.

See Our Featured


  • Proven to have antioxidant effects on the body.
  • May reduce oxidative stress by 40%.
  • Clinical studies were completed on Protandim, not just the ingredients.
  • Green tea and turmeric are proven to boost metabolism and weight loss.


  • Protandim is not a weight loss supplement.
  • No detailed information on ingredient amounts.
  • The only customer reviews available on the website are in video format.


Protandim is quite an impressive supplement in its given category, but that category is not weight loss. While green tea and turmeric may be beneficial for weight loss, we have no idea how much of each ingredient is included in the supplement. It is unlikely that there is enough of either to boost metabolism since this supplement is created as an antioxidant not a fat burner. There should be no negative interactions between this supplement and other fat burners, but it is best to contact your physician before taking Protandim.

7 User Reviews About Protandim

Leave comments below
  • 1

    Love the product am on my 3rd bottle but have concerns. Why am I putting on weight. I have gained 8lbs. The first bottle I lost about 6 lbs, u now have put all back on and more. Please respond.
    Marlene Krueger


    Your Name

    Because protandim is not a weightloss product.this December life vantage will be coming out with a weight loss product.but all protandim is is a pill that triggers a molecule in your body to Rev up the nrf2 molecule syngizer which in returns your body starts making its own antioxidants one a 1 to 1 million ratio over the counter antioxidants work on a 1 to 1 ratio. Your body reduces free radical a whole lot faster, best defense for any disease, linked to the aging process.studies have show several dieases are linked to the aging procss. Because as we age our body slowly stop making antioxidants. That is why we age and get diseases as we get older. This product also has been shown to reduce stress reduce arthritis pain sometimes completely.while using it everyday. Awesome product…I have to say stress is down and I no longer take high blood pressure pills. Pretty much is something my family and I can never go another day without it. I tell everyone I see have you tried Protandim that is at least it’s worth a try scientifically proven to reduce Oxidative stress which is linked to over 200 dieases. Also all natural product.FDA does not have to approve because it’s not a drug.and also does not claim to diagnose or treat and diseases if taken. Only reduces oxidative stress by 40 percent if taken everyday for one month.


  • 2
    bev billingsley

    Can you tell me if ubiquinol can be taken along with protandim. I can’t seem to get an answer from anyone. Thank you.


    Mandy Haney

    Ask your doctor that would be best but you may need to give him so info on protandim. Protandim I do know can’t be taken afterror a kidney transplant because the transplant drugs start to fade from your body producing it’s own antioxidants this I believe over rides alot of prescriptions best to speck with your doctor and have him research protandim but I would after knowing what protandim had done for me and my loved ones


  • 3
    Marjorie La///bell

    could not find price


  • 4
    Earl D Sorensen

    I didn’t know that the product has caffeine in it. I’m not suppose to use caffeine!! Is their tantium in this product also???


    Wayne Wood

    It has no caffeine in it. Where did you hear that?


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