Updated: 07/19/2016 - Site operated by Leptigen

Protandim Review - Does This Health Supplement Actually Work? Are customer complaints and lack of real results deal breakers?

By Summer Banks | Published: 06/28/2016
Protandim Review

Don’t laugh, but well over 50% of diet products simply don’t work. So what about Protandim? Well, we wrote one of our in-depth reviews, scrutinizing the side effects, ingredients, clinical studies and level of customer care. Furthermore, we took a look at dozens of user comments and dieter responses from all over the web. At this point we condensed and summarized to give you with the facts you need.

EDITOR'S TIP: Click here to combine Protandim with a proven fat burner such as Leptigen for better results.

What You Need To Know

To begin, Protandim is a dietary supplement that is intended to reduce oxidative stress through “Nrf2 activation.” The ingredients used in Protandim are milk thistle extract, green tea extract, bacopa extract, turmeric extract and ashwagandha root. According to the official website, this product can lower stress levels by 40 percent in only 30 days. This in turn helps the body function more efficiently, combats signs of aging and reduces damage from free radicals. You should take it with food.

Protandim is made by LifeVantage and it has been available since 2003. This supplement contains natural ingredients and there is convenient contact information on the company website. Furthermore, it’s easy to purchase through the main website, but read on…

Customer Complaints – “Concerning?”

The first thing we address with Protandim ingredients is the number of customer complaints. According to our Research Editor, “There are quite a few user experiences that are not exactly positive. This is a red flag that should not be ignored.”

One customer commented, “This product did nothing for me whatsoever! Don’t buy!”

“Waste of money! My doctor even told me to stop using it,” said another user.

Results – “Lacking”

One doctor commented, “Their product is extremely overrated and they have NO positive human studies whatsoever. The components in Protandim can be acquired on Amazon for a tiny fraction of the cost of what it’s costing now.”

Another person stated, “I do not recommended the use of Protandim. There is no evidence that it provides a health benefit to humans.”

Our research has proven that if there is some particular part of a weight-loss supplement or diet program that is especially burdensome (too many customer complaints, lack of results, high cost) the likelihood of long-term success is quite minimal. So, if Protandim does fail to produce measurable effects in a lot of people, this could be problematic.

The Science – “Valid?”

Although “science” is mentioned for Protandim on the official website, there are no actual clinical trials involving humans, which makes it difficult to determine how well this product actually works. At DietSpotlight, we prefer to see documented research regarding the product and how well it works on people.

The Bottom Line – Does Protandim Work?

Alright, are we out there looking for some Protandim? Well, we like that it contains natural ingredients and a lot of information is presented on the company website. But we have some reservations because no solid science is provided that involves human clinical trials. Also, we’re concerned about the customer complaints and negative comments posted online.

If you’d like to drop more weight, then we encourage you to select a product that is supported by lots of positive user feedback, backed by solid clinical research and sells at a reasonable price.

Among the best products we’ve seen in 2016 is one called Leptigen. Its formula is a proprietary blend of four powerful ingredients, which has been shown in documented scientific research to help accelerate fat loss and ignite metabolism. Also, we can’t find any complaints of harmful side effects and customer comments found online indicate people are seeing great results.

The makers of Leptigen are so certain of their product they’re offering a Special Trial Offer, which is a good sign.

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About the Author: Summer Banks

Summer has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

How Does Protandim Compare?

Previous Protandim Review (Updated April 9, 2014):

What You Should Know

Click Here To See Our Highest Rated Review

At first glance, Protandim does not look like a diet product. The product description talks about reducing oxidative stress, or stress caused by free radicals. This means the supplement contains antioxidants, but there is one proven weight loss ingredient in the formula, so there is some good to be had out of taking this product with an exercise program and healthy meal plan. The complete ingredient list is available on the official website and there is mention of clinical studies. This does not mean clinical studies have been completed directly on Protandim, but we'll see.

List of Ingredients

  • Milk Thistle Extract
  • Bacopa Extract
  • Ashwagandha Root
  • Green Tea Extract
  • Turmeric Extract

Product Features

The two ingredients we are most interested in from a diet point of view are green tea and turmeric. Green tea is clinically proven to boost metabolism, even if the caffeine in green tea is taken out of the equation. The EGCG present in green tea boosts metabolism in addition to the added benefits of caffeine. Turmeric recently hit the weight loss market with some pretty impressive preliminary studies. In the studies, participants who took turmeric lost more weight than participants who did not. Additional large-scale studies replicating this effect are needed before the ingredient is considered clinically proven. While researching the Protandim Ingredients, we found something odd. Under the clinical proof tab we found the clinical proof we'd hoped for, but the study has nothing to do with weight loss. Protandim is clinically proven to reduce oxidative stress. In other words, the supplement works as an antioxidant, which can impact overall health, but not weight loss directly.

See Our Featured


  • Proven to have antioxidant effects on the body.
  • May reduce oxidative stress by 40%.
  • Clinical studies were completed on Protandim, not just the ingredients.
  • Green tea and turmeric are proven to boost metabolism and weight loss.


  • Protandim is not a weight loss supplement.
  • No detailed information on ingredient amounts.
  • The only customer reviews available on the website are in video format.


Protandim is quite an impressive supplement in its given category, but that category is not weight loss. While green tea and turmeric may be beneficial for weight loss, we have no idea how much of each ingredient is included in the supplement. The recall that turned up during our research on Protandim Side Effects also concern us. It is unlikely that there is enough of either to boost metabolism since this supplement is created as an antioxidant not a fat burner. There should be no negative interactions between this supplement and other fat burners, but it is best to contact your physician before taking Protandim.

Protandim Questions & Answers:

We narrowed down hundreds of user reviews about Protandim and created this helpful FAQ.

What are the side effects of Protandim?

Some potential Protandim side effects, reported by customers, include allergic reactions, vomiting, diarrhea, stomach ache, headache and rash.

What are the ingredients in Protandim?

Protandim ingredients include milk thistle, bacopa extract, ashwagandha, green tea and turmeric.

Does Protandim work?

There a several studies listed on the Protandim website. What we noticed after reviewing the research, were the findings didn’t relate to weight-loss, only oxidative stress. Although the supplement contains green tea, an ingredient linked to weight-management, it doesn’t point toward this formula.

You may want to take a closer look at Protandim, what you want out of a dietary supplement and thinking about a supplement like Leptigen, which consists of some clinically-tested ingredients.

How much does Protandim cost?

Protandim costs $50 for a 30-day supply. If you sign up for the auto-ship, the cost is $40.

How should I take Protandim?

You should take one Protandim capsule per day. One bottle lasts a month.

Can I take Protandim if I have a health condition?

Women who are pregnant or nursing, those with health conditions, anyone under 18 years of age or people taking prescription medications should contact a healthcare professional prior to using a dietary supplement of any kind, including Protandim.

What do users like about Protandim?

Some users liked the low price tag of Protandim.

What do users NOT like about Protandim?

Not losing weight was something Protandim users didn’t like.

How do I contact the Protandim customer service department?

You can connect with the Protandim customer service department by calling 1-866-460-7241, emailing a representative at customerservice@lifevantage.com or by mailing correspondence to LifeVantage Corporation 9785 S. Monroe St. Suite 300 Sandy, UT 84070.

Does Protandim contain caffeine?

No, Protandim doesn’t contain caffeine, but the green tea could possibly act as a stimulant.

What is NrF2 in Protandim?

NrF2 in Protandim is a protein supposedly stimulating enzymes to reduce the effects of free radicals.

Why was Protandim pulled from the shelves?

Protandim was pulled from the shelves in 2012 because the company found some lots possibly includes metal fragments.

Does Protandim come with a guarantee?

Protandim does come with a guarantee. You have 30 days to return the supplement for a full refund.

Do you know of any special deals or discounts on Protandim?

There’s no mention of deals or discounts on the official Protandim website. However, our readers have been going wild over the last few months taking advantage of Leptigen’s Special Trial Offer, which is simply the cost of shipping and handling. Click here to give it a try.

13 User Reviews About Protandim

Leave comments below
  • 1
    Rosemary Rickard

    I took Protandim for seven days straight. I watched a you tube video of a guy that swore up and down that Protandim lowered his glucose levels for his type 2 diabetes. I tried it for 7 days and all I got was burning and irritation in my GI tract and my glucose levels went up each day I took it with no change in my low carb diet. I gave discontinued taking Protandim and am returning the product.


  • 2
    Your Angela Name

    Iv been taking protandim for 5 days thinking they get better as they got into my system and Iv felt dreadful I’m not sleeping there making me feel sick and without energy I keep getting hot flushes and headache I felt so badly today I came home and went to bed I won’t be taking them again…


    Your Name

    Are these symptoms above normal ?? Please can you tel me why this as happened taking Protandim.



    Hi there! Sounds like you were having some detox symptoms. Protandim has that effect on our body. Be sure to drink at least half of your body weight in oz. and possibly cut your pill in half until this subsides.


  • 3

    Love the product am on my 3rd bottle but have concerns. Why am I putting on weight. I have gained 8lbs. The first bottle I lost about 6 lbs, u now have put all back on and more. Please respond.
    Marlene Krueger


    Your Name

    Because protandim is not a weightloss product.this December life vantage will be coming out with a weight loss product.but all protandim is is a pill that triggers a molecule in your body to Rev up the nrf2 molecule syngizer which in returns your body starts making its own antioxidants one a 1 to 1 million ratio over the counter antioxidants work on a 1 to 1 ratio. Your body reduces free radical a whole lot faster, best defense for any disease, linked to the aging process.studies have show several dieases are linked to the aging procss. Because as we age our body slowly stop making antioxidants. That is why we age and get diseases as we get older. This product also has been shown to reduce stress reduce arthritis pain sometimes completely.while using it everyday. Awesome product…I have to say stress is down and I no longer take high blood pressure pills. Pretty much is something my family and I can never go another day without it. I tell everyone I see have you tried Protandim that is at least it’s worth a try scientifically proven to reduce Oxidative stress which is linked to over 200 dieases. Also all natural product.FDA does not have to approve because it’s not a drug.and also does not claim to diagnose or treat and diseases if taken. Only reduces oxidative stress by 40 percent if taken everyday for one month.


  • 4
    bev billingsley

    Can you tell me if ubiquinol can be taken along with protandim. I can’t seem to get an answer from anyone. Thank you.


    Mandy Haney

    Ask your doctor that would be best but you may need to give him so info on protandim. Protandim I do know can’t be taken afterror a kidney transplant because the transplant drugs start to fade from your body producing it’s own antioxidants this I believe over rides alot of prescriptions best to speck with your doctor and have him research protandim but I would after knowing what protandim had done for me and my loved ones


  • 5
    Marjorie La///bell

    could not find price


  • 6
    Earl D Sorensen

    I didn’t know that the product has caffeine in it. I’m not suppose to use caffeine!! Is their tantium in this product also???


    Wayne Wood

    It has no caffeine in it. Where did you hear that?


    Your Name

    Green tea has caffeine.


    Kathy pennell

    Green tea has caffeine. Turmeric is a blood thinner. I have tried Protandim twice. Took half a pill to start still got stomach discomfort and other gastro issues.


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