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Mannatech Review - 14 Things You Need to Know

By Summer Banks FNS, SPT, (expert review)

Why is it that so few diet products are backed by science? Let’s see if Mannatech is one of the good companies. We look at supplement ingredients, side effects, clinical research, and customer service quality. We searched for user experiences, though we only found a few. Then, we gathered and summarized them to give you the bottom line.

Mannatech can be purchased through their Official Site.

Mannatech Readers: Noom is offering our readers a risk-free trial, for a limited time. Click here for more information!

What is Mannatech?

Mannatech is a health product and research company based in Texas. They develop and sell various health supplements ranging from weight loss products to fitness products. The company also has a skincare line. One of the best-known Mannatech products is Ambrotose.

Ambrotose is made from a combination of different plant extracts.

Among the weight and fitness products available from the company are OsoLean, TruPURE and TruSHAPE. Let’s see if the main ingredients in these formulas will affect weight, according to research. The main ingredients are whey protein concentrate, xylitol and salacia chinensis extract, respectively.

  • Physiology & Behavior – “Protein is the most satiating macronutrient and is source dependent, with whey protein thought to be particularly satiating.”
  • Nutrients – “We found no human studies on the impact of xylitol on weight, but in mice studies there has been no proven benefits.”
  • Bioactive Compounds in Underutilized Fruits and Nuts – “Studies suggest that extracts of Salacia chinensis regulate multiple enzymes in carbohydrate and lipid metabolism, viz., α-glucosidase, aldose reductase, and pancreatic lipase.”

Mannatech Competitors

Usana Nutrimeal
Juice Plus+
Other similar products:

How Did Mannatech Start? 

The Mannatech MLM company started in 1993 as Emprise International. The founding members were William C. Fioretti, Charles E. Fioretti, Samuel L. Caster, Gary L. Watson, and Patrick D. Cobb. Emprise first started as a pharmaceutical business before branching into nutritional products.

Under a new federal law that approved the use of dietary supplements to promote health and prevent diseases, William Fioretti and Samuel Caster entered the nutrition industry. They hired several scientists from different pharmaceuticals and then started the journey of selling their health products.

The first product sold, made from Manapol – a stabilized product of Aloe Vera, had immense health and healing benefits.

aloe vera inside small container and plastic tub, on top of a green surface

In 1995, the company introduced other Mannatech products including Ambrotose, Manapol, and a few vitamins and minerals. They also changed the company name to Mannatech Incorporated.

Mannatech Incorporated became a huge success and in 1996, received the Biochemistry Discovery of the Year Award. In 1997, Mannatech Incorporated moved to Coppell, Texas, where it started its long journey of selling and researching health products.

Mannatech Customer Testimonials

Mannatech Claims

Mannatech claims that glyconutrients enhance health by boosting the immune system. It contains certain sugars that the body lacks or cannot make naturally. However, this is not substantiated in clinical studies. Some biologists, in fact, counter this claim. They say that there is no connection between glyconutrients and improving the body’s wellbeing.

But the company stands by its claim, continuing to sell glyconutrients to a considerable number of people from all over the world.


Mannatech Ingredients

Prebiothrive ingredients

Ambrotose is a powder that is used as a supplement to support the immune system. It contains glyconutrients that help improve health by giving the body better functioning ability and improving the cognitive and digestive functions.

The major ingredients found in Ambrotose are:

  • Aloe Vera Extract

Aloe Vera is the main ingredient in Ambrotose.

  • Glucosamine HCl

Glucosamine HCI, another ingredient in Ambrotose, is a dietary supplement. Produced by the body naturally, Glucosamine, which is also common in animal products like the bone marrow and in shellfish, is a widely used supplement.

  • Arabinogalactan

Scientifically known as Larix occidentalis and Larix laricina, Arabinogalactan is another ingredient in Ambrotose. It is an extract from barks of the western and eastern larch trees.

This ingredient is also found in red wine, carrots, tomatoes, pears, corn, radishes, and wheat. It boosts the immune system and increases the body’s need for more fiber.

  • Gums

The gum in Ambrotose is from Astragalus gummifer and from the bark of anogeissus latifolia.

  • Rice Starch



Rice starch from rice oryza sativa is not a medicinal or healing ingredient but is a great source of fiber, which helps with digestion, overall health, and well-being.

  • Other ingredients

Their supplements and skin care products are made from natural ingredients. Their essential oils are also from natural ingredients like eucalyptus, lemon, lavender, almonds, coconut and Aloe Vera.

Does it Work?

Does Mannatech Work? 

In Mannatech reviews, several people give varying answers as to whether Mannatech works. While some think it is a complete sham, others praise the healing effects of the supplements. Ben Carson, a retired surgeon and a former USA presidential candidate, swear by Mannatech products.

Some reviewers also say that the official website is easy to read and navigate.

Benefits & Results

Mannatech Benefits and Results 

According to Mannatech, Ambrotose has many benefits. It:

  • Improves the whole body’s cognitive functions.
  • Improves concentration.
  • Supports cellular communication.
  • Improves overall immune system.
  • Enhances your concentration levels.
  • Increases attentiveness.
  • Improves your memory.
  • Decreases irritability.
  • Supports digestive functions.
  • Stimulates your mind.
  • Induces sleep.

Details on Mannatech and Weight Loss 

TruHealth, just like Ambrotose, is a Mannatech product for weight loss and overall body wellness.

The product aims at getting rid of fat in the body, and is in a class of its own according to Mannatech.

metamucil weight loss

According to the company, TruHealth is not your ordinary weight loss product. Unlike many other products where you are required to fast or watch what you eat, TruHealth does not do that. It does not restrict your diet. TruHealth is all about improving your body’s metabolism. It promotes healthy eating and exercise. The system helps you to lose fat while at the same time, build up your muscles.

The system encourages you to eat healthily, exercise regularly, and not cut down on foods that you love. You can continue eating your usual food but make sure to maintain a healthy eating habit while at it.

TruHealth has a 30-day fat loss program. The Lose the Fat for Free program is free to join.

Other Mannatech supplements are: TruSHAPE, fat loss capsules derived from pepper extracts and decaffeinated green tea; TruPURE slim sticks, ImmunSTART capsules, TruREPLENISH Nutritional Shake, EMPACT+ Performance Drink Mix, and OsoLean Sport.


How to Use Mannatech

Mannatech advises all of its customers to take its products as recommended. Some examples of how to take are as follows:

Mannatech Nutriverus

Mannatech Nutriverus is a powder product made from real food. It has many vitamins and contains milk. Its lactose levels are low, and it is advisable to consult a physician before taking Mannatech Nutriverus if you have an allergy to lactose.

The suggested measurement is one scoop per cup. It also contains soy, is gluten-free, and is suitable for both vegetarians and non-vegetarians. It is not for children under the age of 4 years. The product is best with cold items, but you can occasionally use it with hot items.

Ambrotose AO Capsules

These contain Kale, Onion, Tomato, Cauliflower, Pineapple Papaya, Turnip, Cabbage, Carrots, Brussels Sprout, Garlic, and Broccoli. Anyone allergic to any of the ingredients mentioned should not take these.

Omega 3 with Vitamin D3

Some people tend to take more servings of Omega 3 than the recommended dosage. Because of this, Mannatech added Vitamin D3 to the dosage to make servings safer.

PLUS Caplets

These contain Aloe Vera gel, and anyone allergic to this should not take them.

Ambrotose Powder

Only take the recommended servings of Ambrotose powder as anything beyond the recommended dosage might harm you. It contains shellfish, and anyone with shellfish allergies should stay away.

Side Effects

Potential Mannatech Side Effects 

Mannatech Nutritional Supplements may be safe but not everything is as the company says. When taken by mouth in small dosages, the glyconutrients are probably safe.

However, even then, they may still cause thirst, bloating, and flatulence.

myooplex side effects

People with underlying medical condition must consult their doctor first prior to usage. This is because the product makes the immune system more active than it usually is, which may cause health issues for some people. If you are not sure of your health status, it’s better to check with your physician.

Product Warnings

Mannatech Product Warnings

Ambrotose, which is the primary ingredient in almost all Mannatech products, contains glucosamine derived from shellfish. There are quite several people who are allergic to shellfish.

Mannatech warns that anyone who has any allergies to any of the ingredients in their products must consult with their physician. Some of the possible allergens are shellfish and aloe vera.


Mannatech Lawsuits

Mannatech has had several lawsuits since its inception.

In 2004, a mother sued Mannatech and its associates for using her child’s photo to promote one of their products. A nude photo of the child, who sadly died of Tay Sachs condition, was maliciously used as an image of a product promotion, that deceived many people and embarrassed the mother. Mannatech paid $750,000 to settle the case.

In 2007, the Attorney General sued Mannatech and one of the founding members, Caster, for what he said were false claims about the healing power of one of Mannatech products, the Dallas News reports.

In 2008, there was another Mannatech lawsuit accusing the company of generating income through false marketing. Mannatech settled the case by paying $11 million.

In 2009, a Mannatech independent associate and a former senator, Ted Cruz, got embroiled in a lawsuit with Mannatech for trying to have Mannatech products cross over to Mexico where he intended to resell at higher profits.

Mannatech Alternatives


Melaleuca is a wellness company that offers an extensive line of wellness products. The products, according to people that have used them say they work.

The products range from skincare products to home cleaners to supplements with medicinal values.

Like Mannatech, Melaleuca is also a multi-level marketing (MLM) company.

Controlled Labs

Controlled Labs offers its customers health drinks filled with vitamins and minerals. The health drinks are tasty, they have positive effects according to reviews, and come in different flavors.

Mannatech alternatives


They are one of Mannatech’s primary competitors because, for one, not many people complain about any side effects from the drinks. They are also more affordable.


Green coffee Svetol comes in capsules made from natural green coffee extract, green coffee beans, vitamins, and other natural ingredients. According to reviews, it is one of the best products in the market today for weight loss. When you are on Svetol, there is no need to exercise, you do not have to abstain from any foods, and it makes you feel energetic the whole day while at the same time it improves your body’s metabolism. The coffee blocks any fat absorption into the body.


Another excellent product for weight reduction is Herbalife. Herbalife is a tea concentrate made from a healthy tea mix.

It comes in different flavors and is affordable. Herbalife is another alternative to Mannatech that is doing very well in the market.

What Users Are Saying

What Users Are Saying

“I have been taking Ambrotose for over 4 months now and I am thrilled to see how good my cholesterol and glucose numbers are in my recent blood work. Numbers are much better than only 6 months ago. I also have eczema on my feet and it is more in control than it has been in 2 years. I am hopeful that this supplement is making a difference, I would totally recommend it to others at this point.”

“I have been using this product for five years. It has made all the difference in my physical and cognitive health. I highly recommend Mannatech Nutriverus.”

“I’ve loved this product for over 16 years. I take a lot of meds and I want everything cleaned out of my system without stimulation. Manna Cleanse is ready to go when I am and completely empties it all. You feel less weighed down and clean. Less stress on my liver to remove toxins.”

Mannatech Ingredients
Bottom Line

The Bottom Line – Does Mannatech Work?

Let’s take a final look at the facts, shall we? We were looking forward to reviewing Mannatech because it appeared to be a solid company. We were disappointed to see a number of complaints about the supplements doing nothing to promote weight-loss, so we’re skeptical about recommending the line. Plus, there are reports of side effects that leave us concerned.

If you’d like to drop some pounds, we recommend selecting a program that is supported by published clinical research, with excellent customer support.

Among the best products we’ve seen this year is one called Noom. The clinically-proven weight-loss app works with human coaching to connect with people and lead them along the last weight-loss journey they’ll ever need – says Noom.

Plus, the company that makes Noom is quite confident in the program, so they’re offering our readers a free trial offer – nice touch.

Learn More About Noom »
Mannatech Review
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What are the benefits of using Mannatech products?

Mannatech products have a variety of health benefits. Mannatech’s Glyconutrient products are designed to strengthen your immune system and support healthy digestion. Their PhytoCeuticals line is composed of plant-based extracts that may help improve cellular communication, stimulate circulation, reduce inflammation, and promote overall well-being. Additionally, Mannatech’s supplements contain essential vitamins and minerals necessary for optimal health. All of these ingredients work together to make Mannatech’s products an effective choice for promoting total body wellness.

What are the side effects of Mannatech?

Mannatech side effects may include stomach pain, indigestion, and increased blood pressure, based on user reviews.

What are the ingredients in Mannatech?

Ingredients vary by product.

Does Mannatech work?

Mannatech should work to some extent. However, research doesn’t show it is more effective than similar formulas from other companies.

How much does Mannatech cost?

Depending on what you buy, Mannatech products can cost anywhere from $20.00-$280.00.

Where can I buy Mannatech?

Mannatech can be purchased using their Official Site.

How should I take Mannatech?

You should take Mannatech supplements based on the label.

Can I take Mannatech with other fat burners?

You should consult your physician before taking Mannatech with any other fat burners.

Should I diet or exercise on Mannatech?

Though it isn’t required, you may reach your goal faster if you diet and/or exercise while taking Mannatech supplements.

15 Mannatech Reviews

  • Side affects
    Francina (Verified Purchase)

    After taking Mannatech products why is my cheeks turning red, feelvhot and feels as if I have a fever? I am then also feeling very irratated.

  • Richard W

    The product really helps me, So I like Mannatech and trust this company! —-Richard W

  • Hester (Verified Purchase)

    Be carefull. It’s a money making. You apply for a once off payment. Yesterday I received a msg from the bank they tried to debit the same amount out of my account.

    lia de swardt

    Are these products “nappi Coded” ?

  • Anonymous

    Hi I was told empact would help with my breathing problems, I have bad lungs

  • Lilly Mokoene

    I recently bought Mannatech products i have a chronic insomia and control blood pressure .i normally drink my sleeing pills but since i use your products i cant sleep tjis is the 4th fay

  • Joy (Verified Purchase)

    I love these shakes! They worked for me.

  • One more thing...
    More than pleasantly surprised

    Addendum to my other comment: Since I took MT products expecting my health to improve and feel better, I had no illusions or knowledge it would cause a weight loss. So, when that happened, I was amazed. When I told my results to my coworker who sold it to me, who weighed around 180, I was shocked when he told me it caused him to lose 55 lbs, and that he weighed 235 lbs about 6 months prior. I didn’t believe him, so, he showed me his photo when he had that weight. I was blown away! He was a pilot, and said he started taking it so he could pass his medical exam for his continued private pilot’s license.

  • It darn sure worked for me.
    More than pleasantly surprised (Verified Purchase)

    I was referred to MT products by a coworker. He told me about all the positive results for various health issues people have. So, I bought it (aloe vera based products) including Ambratose at his suggestion for my wife, who had some medical issues. She ended up refusing to take it. So, rather than waste my investment, I started to use the product myself. I did absolutely nothing to change my diet. So, I was shocked to see my weight drop over 10lbs in a month of taking it, and, my elevated BP normalized. Mind you, I didn’t FEEL any better, but, the scale told me it absolutely worked. I had no PLACEBO effect. I didn’t know what the product would do to me. Also, I never felt ill taking it. When I stopped taking it, gradually my weight crept back up.

  • Junaid

    Is it sure i am not gona get any side effect

    • Anna (Editor)

      Hello. All users are different and can experience different side effects; please make sure to consult with your physician before taking this product. Another supplement you may want to check out before buying Mannatech is Dietspotlight Burn. We like that it has clinically researched ingredients.

  • Meliss Pratten

    is it ok for diabetics?

    • L Muller

      Yes, I would suggest you use MT Ambrotose as well as the OSP package to help with your sugar levels

  • Este Smith (Verified Purchase)

    I use MT products and are more than happy! Will never go without it ever again! I feel amazing!

  • Love mannatech
    Bernadette (Verified Purchase)

    Absolutely stand by these incredible products. I went on the weight loss program for 3 mths on there 90 day challenge. In that time I lost my unwanted 14 kgs and just can’t live without them. Today. There service is impeccable and I highly recommend them. 100% money back guaranteed, now what company offers that.

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