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Metagenics Review - 15 Things You Need to Know

Health and wellness company Metagenics offers a number of products, focusing on everything from protein bars to multivitamins. While the company offers a lot of education on the metabolic process, the information is vague and not pertain specifically to Metagenics products. In fact, the website reads more like an infomercial, encouraging physicians to promote Metagenics products to their patients.

The crew found a number of alternatives that could leave your wallet far less empty and still deliver similar results. Do Metagenics products offer something truly different? We looked at their ingredients and the science behind them in-depth. We have a summary of everything we learned here.

Metagenics can be purchased through their Official Site.

Metagenics Readers: Noom is offering our readers a free trial, for a limited time. Click here for this special offer!

What is Metagenics?

Metagenics is a health product and supplement company that partners with medical practitioners to treat a wide variety of patients. They produce everything from multivitamins to probiotics to whey protein powder for athletes and dieters.

Their customer base includes people of all ages including children, men, women, and the elderly. In addition to working with medical practitioners, the company regularly hosts webinars, seminars, and other events to educate people in the healthcare field.

They also partner with a number of top universities to conduct research and develop new formulas. Avid advocates for social change, Metagenics aspires to be environmentally friendly and regularly donates to children and conducts food drives for people in need.

According to the company, users of Metagenics products benefit from transparent labels and have access to hundreds of gluten-free, vegetarian, and non-GMO supplements and food items. Metagenics supports healthy living in many ways including weight loss, nutrition, stress-relief, sports recovery, and deficiencies.

Uses of Metagenics products range from supporting good health and vitality to playing a role in treating chronic diseases and life-disrupting issues like stress. These supplements and food items are only available to those working with approved Metagenics partner practitioners, which can be found based on location through their main website.

Metagenics – The Company Behind the Products

Metagenics is a company that manufactures food supplements, vitamins, and other similar products. The company uses genetic data to create a nutrition plan for the wellbeing and health of particular customers taking into account the uniqueness and individuality of each person. This company markets their products worldwide. Metagenics works with MetaProteomics, LLC; a company specializing in biotechnology.

Metagenics Competitors

Usana Essentials Multivitamin
Advocare 24-Day Challenge

Metagenics Ingredients

The company strives to include only the best ingredients which means often filtering out GMOs, gluten, and other common allergens and problematic ingredients. Since this company has so many products, it’s difficult to list all of the ingredients in every supplement.

However, we can break down the Metagenics ingredients in some of their earliest and most popular products to provide an example of what goes into their formulas. One of the earliest Metagenics products, the Lactobacillus Acidophilus supplement represents early and popular products among users.

Their current UltraFlora Intensive Care supplement includes twenty billion live organisms of Lactobacillus plantarum as well as potato starch and magnesium stearate. This is just one of many gut health products sold for practitioners and patients.

One of the most comprehensive and widely used products from Metagenics today, however, is the standard multivitamin. The Metagenics multivitamin supplement includes:

  • Vitamin A
  • Vitamin C
  • Vitamin D
  • Vitamin E
  • B Vitamins
  • Calcium

Vitamin A

Vitamin A is derived from beta-carotene and retinyl acetate in this multivitamin. According to National Institutes of Health, scientists and medical professionals have found that Vitamin A supplementation supports immune function, reproduction, vision, and communication between cells.

It’s also a key player in the formation and maintenance of vital organs such as the heart, lungs, and kidneys.

Vitamin C

Vitamin C is derived from ascorbic acid in this product, and is included to improve immune function, maintain skin health, support bones and blood vessels, and act as an antioxidant. As an essential dietary component, it is recommended that people over 18 intake at least 65 mg per day through food and vitamins.

Vitamin D

National Institutes of Health claims that Vitamin D is found in few foods but is produced when the skin is exposed to sunlight. This vitamin is important to many things but most notably bone health, cell growth, and immune function. Vitamin D supplementation through multivitamins is particularly crucial for those who receive very little sunlight.

Vitamin E

According to National Institutes of Health, vitamin E is an antioxidant fighting free radicals in the body and prevents chronic diseases. Established adequate intake of Vitamin E is 15 mg for adults and at least 4 mg for infants and children.


B vitamins in this product include Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Biotin, and Pantothenic Acid.

Thiamin, or Vitamin B1, plays a role in converting food into energy as well as cell function and growth, based on information from the National Institutes of Health.

Niacin plays key roles in the skin, nerves, digestive system and helps convert food to energy.

Vitamin B6 metabolizes proteins, folate supports DNA synthesis, and Vitamin B12 is also required for proper DNA synthesis as well as neurological function and red blood cell formation.

Biotin is known for supporting healthy hair skin and nails; while pantothenic acid helps the body break down food, makes fatty acids, and aids growth, as reported by NIHODS.

The multivitamins also contain calcium, which is, according to National Institutes of Health, a mineral that is essential to bone health and vascular function, as well as Iron, phosphorus, iodine, magnesium, zinc, potassium, copper, and more.

Does It Work

Does Metagenics Work?

Many people wonder whether these products and supplements work, but this is largely subject to the patient and their condition of health.

Patients with simple deficiencies may find that these supplements can heal their ailments quickly, while others may use these products to relieve symptoms of chronic diseases and gradually restore good health.

Vitamins can quickly cure deficiencies, but probiotics, for example, restore gut health and aid the immune system’s ability to ward off illness at a gradual pace.

Oftentimes, products don’t work because they aren’t being used properly. People may even buy the wrong supplements for their needs or they may not follow the directions properly.

Metagenics minimizes these possibilities by requiring customers to work with healthcare professionals to use their products.

With the guidance of a certified healthcare professional, users have a better chance of using the right products and taking them as directed.

This improves the likelihood of the products working as they should and minimizes cases of misuse and unsuccessful treatment.

However, it’s important to remember that this does not guarantee that all Metagenics supplements will work as intended.

Benefits and Results

Metagenics Benefits and Results

The benefits of Metagenics are vast due to the sheer number of products available to users.

For example, users taking multivitamins can benefit from improved health and vitality while users on weight loss supplements can slim down and minimize risks heart issues.

In general, the benefits of Metagenics supplements and food items include:

  • Improved nutrition
  • Boosted immunity
  • Weight loss
  • Stress relief
  • Improved neurological health
  • Healthier bones and tissue
  • Athlete support
  • Sports recovery
  • Child health and wellness
  • Detoxing

Various Metagenics supplements contribute to general health and immunity while others focus on weight loss, fitness, or stress relief.

Some supplements contribute to healthy neurological functioning while others focus on improving bone and muscle health.

Specific products are also dedicated to athletes and helping people recover from sports injuries.

Many of the available products extend to young people and support the health of teens and small children.

In addition, Metagenics offers products to help people safely detox and improve their mood, sleep, and energy levels.

Details on Metagenics and Weight Loss

Metagenics supplements designed to help people lose weight include:

  • Healthy Transformation Weight Loss Program
  • Whey protein powders
  • Soups
  • Shakes
  • Recipe books,
  • Exogenous ketone salts
  • Protein bars

People should work with their health practitioner in choosing which products to use to reduce their weight and lower their body fat.

Having the guidance of a health professional can increase the chances a patient will lose weight while using Metagenics supplements and food products.

Most of these products are to be used as a part of a healthy diet plan but should not typically account for 100% of a person’s food intake.

For example, soups, shakes, and protein bars may replace some meals but the user’s diet should also consist of healthy foods such as fruits and vegetables.

Unfortunately, there are no reviews available to assess how well Metagenics supplements support weight loss.

How to Take Metagenics

Directions for Metagenics supplements are clearly provided on their website and on every product label.

In addition, Metagenics users can rely on their health practitioner’s guidance for directions and specific instructions for their condition.

Some healthcare professionals may advise their patients to take their supplements in a different way than listed on the packaging, so it’s important for Metagenics users to carefully listen to their healthcare practitioners.

Metagenics prides themselves on transparency and clear ingredients and directions.

For example, according to their website, multivitamins should be taken at least once per day or as directed by a practitioner, stress management supplements like MyoCalm should be taken up to three times per day or as directed by a practitioner, and glucose support supplements like Insinase should be taken three times per day or as directed by a health professional.

Product Warnings

Metagenics Product Warnings

Each product comes with a cautionary statement to the user depending on what the product does and how it’s intended to be used.

However, most products come with a warning to keep them away from children who may unknowingly ingest them.

Many products are also not to be used by pregnant or nursing women for the sake of the mother’s and child’s health.

Many of the products also advise getting the approval of a physician before using if taking other medications, but this warning seems unnecessary since using Metagenics requires the guidance of a certified practitioner.

Is Metagenics Safe?

Many Metagenics supplements are regarded as safe, but they come with warnings to help users and practitioners make good decisions when choosing products to take or use.

In addition to having transparent ingredient labels and providing warnings, Metagenics increases the safety of their products by requiring users to consult with partner medical practitioners.

While this does not completely prevent negative side effects, it reduces the chance of taking the wrong supplement or taking too much or too little of a product.

Since medical practitioners are extensively educated in human health, consulting with them prevents simple errors and can even improve the overall outcome of a patient’s supplement treatment.

Side Effects

Metagenics Side Effects

Metagenics offers hundreds of products, and each of them differs in side effects that can occur in users.

While some products list no side effects, others list potentially dangerous side effects that can affect various people.

Stress relief supplements also come with various side effect warnings. Some of the listed side effects of Metagenics stress management products include drowsiness and negative interactions with medications or alcohol.

Other products contain warnings concerning gastrointestinal upset and other minor side effects that are unpleasant but not dangerous.

Metagenics Lawsuits

As of January 2019, a class-action lawsuit against Metagenics was settled for $1.3 million, according to Top Class Actions. The suit claimed the foods were falsely advertised as aiding with medical conditions, which is neither proven or legal to claim without FDA review and classification as a drug.

In 2016, the Australian Government recalled Metagenics NasoClear for potential bacterial contamination.

Alternatives to Metagenics Products

The best way to achieve weight loss, a better lifestyle or just plain healthy living is to find a balance between healthy eating and a good exercise routine. If specific health concerns are present, a doctor should always be consulted.

Metagenics Prices

The prices of Metagenic products vary depending on the product. The products can be purchased on the company’s website and on Amazon, other online shopping sites, and wellness and nutrition websites. The cost of Metagenics products is high compared with other weight-loss supplements.

Pros and Cons

Pros and Cons of Metagenics Products


  • The company is very accessible via its website and through customer service.
  • The company is quickness to respond to customers, and the company website contains answers to commonly asked questions.
  • The company ships worldwide.


  • The prices are quite high relative to other health supplements.

What Users Are Saying

“Metagenics is one of the few supplement/vitamin brands that my physician recommends. Since not regulated by the FDA, it’s important to trust your preferred brand so you know that you are getting the nutrients (and only the nutrients) listed on the label and the quantity on the label. These itty bitty vitamin D capsules keep my spirits high when I’m stuck in an office during Seattle’s cloudy season. HIGHLY RECOMMEND.”

“Nice product and works for my mom, but did absolutely nothing for me.”

“The jury is still out on this one. I didn’t feel well after taking it, so I stopped it. I’ll try it again in the future, and if I feel unwell again, I’ll discontinue it permanently.”

Bottom Line

The Bottom Line on Metagenics Products

Are we calling up our doctor right now to see if Metagenics is the right choice? Well, there are pros and cons, so we have some reservations. The taste is good for some but not for others. The price is okay if you look at the quantity, but only for a select few. According to NCBI, there’s also the issue that meal replacements are available in just about any grocery store or supercenter out there so you don’t have to visit the doctor.

If you want to use a meal replacement to lose weight that’s a good choice. But, consider maximizing your weight-loss potential by adding a clinically-proven app that helps dieters reach their goals faster.

Among the best products we’ve seen this year is one called Noom. The program is different from other apps as it uses human coaching to help users reach weight-loss and health goals. We love that it is clinically proven and that nutritionists and doctors support the program because it just works.

Plus, the company behind Noom is confident enough in their program to give Dietspotlight readers a free trial.

Learn More About Noom »
Metagenics Review
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What are the side effects of Metagenics?

Possible Metagenics side effects may include headache, dry mouth, nausea, stomachache, changes in bowel movements and allergic reactions. This is according to some user reviews.

What is in Metagenics?

The Metagenics ingredients include (for the Healthy Transformation Weight Loss Program) whey protein isolate, maltodextrin, natural flavors, lactobacillus acidophilus, bifidobacterium lactis bi-07, inositol, green coffee bean, omega fatty acids, Chinese cinnamon bark, bitter melon fruit, green tea leaf extract, and various vitamins and minerals.

What is the active ingredient in Metagenics?

The active ingredient is whey protein concentrate, which can work to reduce hunger.

Does Metagenics work?

Although we did not find any clinical data to support Metagenics for weight-loss, if you combine these supplements with a low-calorie diet plan and regular exercise, you may experience some weight reduction. After all, reducing your daily calorie intake and engaging in regular physical activity can help you shed some pounds.

How much does Metagenics cost?

The prices for all Metagenics products vary. As for the Healthy Transformation Weight Loss Program, it sells for $249.95. This is a 30-day supply.

Where can I buy Metagenics?

Metagenics can be purchased using their Official Site.

How do you take Metagenics?

You need to follow the instructions presented on the bottle or packaging. These bars, shakes and pill supplements can be used daily.

What is Metagenics diet?

The Metagenics diet focuses on increased plant-based foods, decreasing irritating foods, and balancing the body.

Is Metagenics FDA approved?

Metagenics products are not approved by the FDA.

How do I get Metagenics?

You actually have to buy Metagenics products through a licensed practitioner.

Is there a solid refund guarantee offered with Metagenics?

Yes, you are able to return Meta products within 30 days if they are unopened.

Does Metagenics specialize in weight-loss?

No, Metagenics is more of a health supplement brand. However, they do offer a few weight-loss products.

Is Metagenics organic?

Metagenics products use organic ingredients when possible, but their products are not certified organic.

20 Metagenics Reviews

  • First ever detox
    Julie (Verified Purchase)

    I have just commenced Therophase detox essentials (day 2)
    I feel like I have been hit by a truck and I haven’t been having my recommended pm dose.
    Should I stop or push through, everything is aching

    • Sasha

      Hi Julie, if you are experiencing negative side effects, we suggest consulting with your doctor before continued use.

  • Chrissy

    I have epilepsy. I read that this helps with it. So far I have not read anything where it really would help me at all or anyone with any medical conditions

  • Tanya

    I have been on femex for the past month and have stopped and started use a few times (due to illness) could this cause a change to my menstrual cycle? Since using it I have had 2 periods in 30 days. Wondering if this could be a side effect?

    • Veronica

      Hello Tanya. All users are different and can experience different side effects; please make sure to consult with your physician before taking this product and let them know about the irregular menstrual cycle you were experiencing.

  • Aaron

    The company helps the employees with anything that is needed, daily and hourly availability. from question specialist, to detailed solutions to help people.

    a person couldn’t ask for a better system to be successful and healthy.

    they are super friendly from the top of the company – to the person who answers the phone right up to the Doc himself.

  • robert kimtis

    is neurosol still available? can’t seem to order it online.

    • Veronica

      Hi Robert! For more information on where to purchase this product, please refer to the Metagenics official website.

  • Tina

    I have always been anti-protein shakes. I specifically take issue with consuming some frankenstein product/food developed in a lab. I started with the glucose mix and so far it has been working well. My energy levels are consistent through the day. In terms of diet program – what I like about it is they offer all of their information online for free. Other meal replacement shakes/diet programs only give you the eating suggestions after you’ve purchased the product and it usually comes in a kit.
    Since trying Metagenics, I’ve been curious about how other protein shakes taste – so far I’ve been completely disappointed. Most are sweetened with artificial sweeteners which I can’t have. I’ve tried some that are stevia sweetened in the past couple weeks just to see what tasted better and they were all gross – I would say extremely chalky and difficult to mix.
    It’s a little expensive. I’m not sure how much compared to other similar products but if you live in the US, contribute to a 125 plan through your work, you can use that money to buy the product – that way at least your spending tax free money.

    • Glenn (Editor)

      Hi Tina. Having the best products to add to a diet is important to us all. You may want to consider one like Dietspotlight Burn; which contains clinically-tested ingredients. Click above to learn more about it and the free sample.

  • Misty (Verified Purchase)

    My doctor recently recommended that I drink one Metagenics shake each day as a meal replacement as we work on balancing out my body chemistry to reverse some issues I’ve had come up. I really like the flavor and texture of the Metagenics powder, and the fact that it mixes well with just a spoon rather than needing a blender or bullet mixer to get all the powder dissolved. The price is a definite prohibitor though. It cost me $150 for a 30-serving supply from my doctor’s office. I found it on Amazon, but the price was the same. Another doctor recommended Unjury protein powder a few years ago to help me lose weight. It’s about 1/3 of the cost of the Metagenics, and also has a very good flavor and texture. There are some differences between the Metagenics and the Unjury powders, but I don’t really know enough about nutrition to be able to accurately gauge which one is the better option outside of price. At first glance, Unjury seems to make more sense as it has more protein and significantly fewer calories and carbohydrates. (The only place I’ve found to buy Unjury so far is on their website.) I’ve been looking online to see if I could find someone who’s reviewed both brands from a nutritional standpoint and rated them, but I haven’t found a comparison of the two yet.

    I plan to use the Metagenics I bought from my doctor since I have it, but I’m going to take my empty Unjury container with me when I go back for my next follow-up meeting and ask her if there’s any reason I couldn’t use that instead since it’s significantly less expensive.

  • My profession
    Dr don plance

    I have been doing sports med for nearly all pro types and colleges as well as younger and older weekend athletes. I do vector and injury risk Evals, modify also based on familial and genetics.
    As I do this more I find that of all the protein mixes I use, yours has bar far exceede and is now after 36 of this work, am going to select yours as my number one. Next week I will be giving a one time 6 oz mixture of ur protein and my addition based on other dxs. Please contact my office. I would certainly appreciate any discount for office use and coupons for my pts

  • Is this the right product for me?

    I have the acute phase product. I recently has a shoulder repair surgery. Is this the correct product for optimal healing of soft tissue? Also, where is the raw pancreas harvested from ? Thank u

  • Loved the product.
    Christina (Verified Purchase)

    I was on the Metagenics weight loss clinical trial that evaluated their hops extract. I lost 40 lbs during the study. As part of the study, I discovered that I have genes that make it difficult for me to lose weight. BTW, Metagenics offers a diet, supplements, and support programs that made this diet successful for me. The chemistry of the diet was perfect for my body to lose weight.

    • Avril

      How long were you on this diet for and how did you not gain afterwards?

  • Want to try each flavour
    jean murrey

    why can we only buy the shake in packets of about 17 costing a lot of money. I would like to be able to buy one of each flavour and then choose which I prefer. But I have to buy the whole packet of

    • tina murrey

      My doctor prescribed Metagenics medical foods for me to lose weight. I was on a program which included Ultra Meal twice a day. I lost 10 pounds in 2 months. So, I think it’s a great product

    • Glenn (Editor)

      Hi Jean. Having an affordable product is important. One that’s priced right and contains the ingredients you need is one called Dietspotlight Burn. Click above to learn about the sample offer.

  • Fibroid Tumour and Estrofactor

    Hi there,
    I have a fibroid tumour and have been recommended Estrofactor by my dieitician. I have for 2 days had severe cramps, similar to period pains but worse than usual and I have a high pain threshold. I take Yaz and normally never experience any PMS type symptoms as a rule.

    This was recommended for me due to low Estrogen levels – I am 43

    Can I keep taking this product with these kinds of symptoms?

    • Yedy Torres

      Hi Anne-Marie,

      We would recommend to speak to your physician first before taking this product.