Updated: 07/18/2017

GNC 2-Day Cleanse Review- Does This Cleanser Work?

  • 9 User Comments
  • Rating: 3.0. From 34 votes.
By Summer Banks Jul 12, 2017

Why are people talking about GNC 2-Day Cleanse? We wanted to know, so we turned our attention toward ingredients, side effects, clinical research and customer service quality. Additionally, we analyzed hundreds of user comments and reviews. Then, we summarized and refined to give you the info you need.

GNC 2-Day Cleanse Readers: Click here to find out why we're giving away samples of our product, Dietspotlight Burn.

What is GNC 2-Day Cleanse?

The GNC 2-Day Cleanse ingredients are purified water, juice cleanse blend, green coffee bean extract, garcinia cambogia fruit extract, green tea leaf extract, lychee, dandelion whole plant extract, mango fruit, burdock root, vitamins and minerals. [1] [2] It promotes weight-loss by removing toxins from the body and improving digestive health. You’ll drink one bottle, twice daily, prior to meals.

GNC is the company behind the product. They’ve been in the business for years, although GNC 2-Day Cleanse is relatively new. You can purchase the supplement on the official website or local stores. We like that contains a few natural ingredients and that we located some positive customer comments, but read on…

Side Effects – “From Natural Ingredients?”

The first concern related to GNC 2-Day Cleanse side effects. “When we looked at this profile, we found it contained a few natural ingredients,” said our Research Editor. “After a closer look, we also noticed several of the components cause adverse reactions.”

“I could barely get the bottle down and even after I did I felt very sick to my stomach,” commented a customer. [3]

“It made me really gassy,” stated another. [4]

On the other hand, we found some dieters that didn’t experience negative side effects.

“It’s something that I wouldn’t be opposed to trying again down the road seeing as the side effects during it were minimal,” stated a consumer.

GNC 2-Day Cleanse Ingredients – “Nothing to Help You Lose?”

The GNC 2-Day Cleanse ingredients not producing results was a concern mentioned in customer reviews. “One star cause there’s no zero. Took the product as instructed. The only thing that was cleansed was my wallet.”

Another shared, “Tasted bad…did nothing for me…total waste of money.”

There were a few that did notice results, including some weight-loss.

“Easy to use, never hungry, lost 2.8 pounds in 2 days. Great way to jump start diet,” said a user.

What our research has told us that when any particular part of a supplement is considered troublesome, such as not supporting weight-loss, there’s a slim chance of long-term success. Is it really worth it if GNC 2-Day Cleanse doesn’t produce results.

The Science – “Backed by Research?”

The company offers no scientific proof that the GNC 2-Day Cleanse will in fact promote weight-loss, or enhance health in any area. While cleanses are generally recognized to offer some benefits, there is no actual research provided. We do know the act of increased bowel movements and water loss will change the scale, this is only temporary. [5] Here at DietSpotlight, we are looking for something that helps you lose more and we didn’t find that this time.

The Bottom Line – Does GNC 2-Day Cleanse Work?

What’s our take on losing weight in 48 hours? Well, we like that GNC 2-Day Cleanse ingredients are natural and that the company has a foothold in the industry, but research supporting the claims leaves us concerned. We’re also a bit skeptical about this one because customers are talking about the lack of results and the harmful side effects.

We want you have long-term success, not just for 48 hours. So, we suggest going with a supplement containing ingredients shown to work, not linked to harmful side effects and supported by positive customer comments.

Among the best products we’ve seen this year is Dietspotlight Burn. The supplement promotes weight-loss by featuring four clinically-tested ingredients which have been shown to help accelerate metabolism and ignite weight-loss. There’s no one talking about harmful side effects, but there’s chatter about users seeing great results.

The makers of Dietspotlight Burn are so confident in their supplement, that they’re offering customers a special trial offer, truly impressive.

Previous GNC 2-Day Cleanse Review (Updated August 14, 2012):

What You Should Know About GNC 2-Day Cleanse

GNC offers dieters a long list of products and supplements to lose weight, cleanse and build muscle, but not all products are safe and effective when it comes to promoting long-term weight loss. The GNC 2-Day Cleanse is a liquid cleanse that dieters use with natural, organic foods to reverse the damage caused by eating processed foods common in western diets. We found no clinical support that this cleanse would improve health or repair any part of the digestive or elimination systems of the body. There is also no proof the cleanse will increase weight loss.

List of Ingredients


  • Purified Water
  • Whole Apple Concentrate
  • White Grape Extract
  • Aloe Vera Gel
  • Milk Thistle Extract
  • Green Tea Leaf Extract
  • Citrus Bioflavonoid Complex
  • Acai Fruit
  • Spirulina
  • Grape Skin Extract
  • Pineapple
  • Apple
  • Orange
  • Chlorophyll
  • Goji Berry Extract
  • Broccoli
  • Tomato
  • Brussels Sprouts
  • Cauliflower
  • Blueberry
  • Grape
  • Grapefruit
  • Plum
  • Raspberry
  • Strawberry
  • Watermelon
  • Celery
  • Kale
  • Spinach
  • Lemon
  • Lime
  • Papaya
  • Cantaloupe
  • Cherry
  • Peach
  • Pear
  • Radish
  • Onion
  • Leek
  • Yellow Pepper
  • Fibersol
  • Maltodextrin Soluble Fiber
  • Xanthan Gum
  • Apple Pectin
  • Carrot Fiber
  • Beet Fiber
  • Citric Acid
  • Potassium Phosphate
  • Natural Flavors
  • Potassium Sorbate
  • Sodium Benzoate
  • Calcium Ascorbate
  • Sucralose
  • Niacin
  • D-Calcium Pantothenate
  • Acesulfame Potassium
  • Folic Acid
  • Pyridoxine HCL
  • Riboflavin
  • Thiamin HCL
  • Chlorella Algae
  • Kombu
  • Wakame
  • Nori
  • Oat Fiber
  • Soybean Fiber
  • Brown Rice
  • Chicory Root
  • Jerusalem Artichoke Tuber
  • Acerola Berry Extract
  • Licorice Root Extract
  • Astragalus Root
  • Barley Malt
  • Mung Bean
  • Soy Sprouts
  • Wheat Berry
  • Eleuthero Root Extract
  • Pomegranate Fruit Extract
  • Cranberry Concentrate
  • Barley Grass
  • Jasmine Tea Extract
  • Trace Minerals
  • Cyanocobalamin

Product Features: GNC 2-Day Cleanse

The list of ingredients for GNC 2-Day Cleanse is extraordinary, but the liquid concentrate supplies tons of vitamins via vegetables and fruits. There are several sources of fiber to promote cleansing, but the cleanse is natural as the sources of fiber are bulk-forming or lubricating and have no stimulant properties. GNC even adds potassium to the mix to replace any water lost from increased bowel movements and urination that may be associated with the intense push of fruit juices.

Advantages of GNC 2-Day Cleanse

  • Relatively healthy cleanse.
  • Supplies various sources of natural fiber.
  • May help kickstart a healthy eating plan.

Disadvantages of GNC 2-Day Cleanse

  • Will not necessarily promote weight loss.
  • The cleanse will have no effect if the dieter continues to eat processed, unhealthy foods.


In the cleansing market, GNC 2-Day Cleanse is one of the healthiest options a dieter can choose. The cleanse will increase urination and may increase bowel movements, but it will not cause diarrhea or loose stools like stimulant laxatives.

This is a 2-Day Juice Cleanse formulated to jump start a new diet plan. It removes unwanted toxins to jump start your metabolism.

GNC 2-Day Cleanse Ingredients and Supplement Facts

Serving Size: 1 Bottle
Serving Per Container: 4
Amount per Serving% DV
Vitamin A**
Vitamin C**
Vitamin E**
Vitamin B-6**
Vitamin B-12**
Pantothenic Acid**

Other Ingredients: None

  • References
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GNC 2-Day Cleanse Side Effects:

GNC 2-Day Cleanse is made from natural ingredients. Most people have used it without experiencing negative side effects. Based on our research, the following side effects have affected users in a small number of cases. While that isn’t the norm, it’s wise to proceed cautiously with new products.


One of the most commonly claimed side effects of GNC 2-Day Cleanse is nausea. When you’re nauseous, you feel like you’re on the verge of throwing up. You lose all appetite. You feel dizzy and sweaty.

What causes nausea?

Nausea is often caused by motion sickness, such as when you’re traveling in boat, car, or airplane. There are also health conditions known to cause nausea. The most prominent are stomach virus/bacteria, food poisoning, ulcer, and gallbladder disease. [1] Even tasting, smelling, or seeing something distasteful can be enough to make you nauseous.


Bloating is when your stomach increases in size. The change in noticeable to the eye and to the touch. Usually, bloating comes with slight nausea. You also feel sluggish and heavy. Gassiness is typical.

What causes bloating?

Appendicitis, Crohn’s disease, irritable bowel syndrome, and urinary tract infection are among the chief causes of bloating. You may be suffering from indigestion. Or you may simply be bloated due to eating too much.

Stomach Pain

Stomach pain can be very debilitating and discomforting. Normally stomach pain takes the form of a tightness or acute pressure in your abdomen. Depending on the type of stomach pain, you may also have gas, bloating, and nausea.

What causes stomach pain?

Contracting a stomach virus, bacteria, or parasite can make your stomach hurt—and also provoke other problems in your digestive system. Kidney stones, pelvic inflammatory disease, and food intolerances also cause stomach pain. [2]


A case of diarrhea can really ruin your day. When you have diarrhea, your stool is watery and loose. You feel the urge to go to the bathroom as often as every few minutes. Because you pass stool so often, your rectum gets sore. And the liquid nature of your stool depletes your body fluids—potentially leaving you dehydrated.

What causes diarrhea?

Irritable bowel syndrome, bacteria, parasites, and viruses are the main triggers of diarrhea. Diarrhea can also occur when you have a fever. Some people even get diarrhea from running, a condition known as “runner’s diarrhea.” GNC 2-Day Cleanse is safe under most circumstances. Because it’s uncertain how your body will respond to the ingredients, it’s a good idea to talk with your doctor before beginning use.

GNC 2-Day Cleanse Questions & Answers:

We focused on all kinds of user comments and feedback about GNC 2-day Cleanse. At this point we summed up everything into this helpful FAQ.

What are the side effects of GNC 2-day Cleanse?

Possible GNC 2-day Cleanse side effects may include upset stomach, bloating, diarrhea, nausea and gas. This is based on customer reviews.

What are the ingredients in GNC 2-day Cleanse?

GNC 2-day Cleanse ingredients are purified water, whole apple concentrate, white grape extract, aloe vera gel, milk thistle extract, green tea leaf extract, citrus bioflavonoid complex, acai fruit, spirulina, grape skin extract, pineapple, apple, orange, chlorophyll, goji berry extract, broccoli, tomato, brussel sprouts, cauliflower, blueberry, grape, grapefruit, plum, raspberry, strawberry, watermelon, celery, kale, spinach, lemon, lime, papaya, cantaloupe, cherry, peach, pear, radish, onion, leek, yellow pepper, fibersol, maltodextrin soluble fiber, xanthan gum, apple pectin, carrot fiber, beet fiber, citric acid, potassium phosphate, natural flavors, potassium sorbate, sodium benxoate, calcium ascorbate, sucralose, niacin, d-calcium pantothenate, acesulfame potassium, folic acid, pyridoxine hcl, riboflavin, thiamin hcl, chlorella algae, kombu, wakame, nori, oat fiber, soybean fiber, brown rice, chicory root, Jerusalem artichoke tuber, acerola berry extract, licorice root extract, astragalus root, barley malt, mung bean, soy sprouts, wheat berry, eleuthero root extract, pomegranate fruit extract, cranberry concentrate, barley grass, jasmine tea extract, trace minerals, and cyanocobalamin. [1]

Does GNC 2-day Cleanse work?

First off, this product contains five grams of fiber. This should help with more regular bowel movements. GNC 2-day Cleanse also contains various fruits and vegetables. These provide vitamins and minerals to help nourish the body. This formula contains antioxidants to help combat harmful free radicals. However, we did not find any clinical studies on the company website to support this cleansing drink as a means of promoting weight-loss.

You may want to consider replacing GNC 2-day Cleanse with a product that uses clinically tested ingredients for weight-loss. One option is Dietspotlight Burn.

How much does GNC 2-day Cleanse cost?

According to the official website, GNC 2-day Cleanse sells for $29.99. However, if you are a member, this product costs $26.99.

How should I take GNC 2-day Cleanse?

You only need to use GNC 2-day Cleanse for two days. It should be consumed twice a day, 30 minutes before meals. One 12-ounce bottle is a serving.

How do I contact GNC customer service?

You can get in touch with GNC by calling 1-877-462-4700. There is also a store locator tool provided on the website. You can find the nearest location by entering your zip code.

Can I take GNC 2-day Cleanse if I have a health condition?

Those taking prescription drugs and people with health conditions need to talk to a doctor before using this cleanse product. Also, women who are pregnant or nursing should not take GNC 2-day Cleanse. Nor should individuals under the age of 18.

What do users like about GNC 2-day Cleanse?

Some customers like that GNC 2-day Cleanse increases bowel movements. Others appreciate that this diet product contains various vitamins and minerals. [2]

What do users not like about GNC 2-day Cleanse?

Some users do not like the taste of GNC 2-day Cleanse. Furthermore, some people have mentioned certain side effects. Also, there are complaints that this product does not produce real results.

Is there a diet plan with GNC 2-day Cleanse?

Yes, there is a nutrition plan included on the box.

Can diabetics use GNC 2-day Cleanse?

You must consult your doctor to find out more.

Is there a return policy for GNC 2-day Cleanse?

Yes, GNC offers a 30-day satisfaction guarantee.

Do you know of any special deals or discounts on GNC 2-day Cleanse?

The only discount we know of is the membership price for GNC 2-day Cleanse, which is $26.99. On a separate note, a number of our readers have been excited about Dietspotlight Burn’s special trial offer, which is just the cost of shipping and handling. Click here to try it out.

Learn More About Dietspotlight Burn »
Summer Banks Dietspotlight Author
About the Author:

Summer Banks, a content strategist at Dietspotlight, has researched over 5000 products in the past 10 years. She has years of nursing training, experience as a manager responsible for 15 supplement brands, and completed coursework on Food and Nutrition from Stanford University. full bio.

Rating: 3.0. From 34 votes.
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GNC 2-Day Cleanse Review

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Leave a comment or review

  Can this cause headaches?

Can this cleanse cause headaches?

Maribel (Editor)

Hi. Please make sure to consult with your physician before continuing to take this product and let them know about the side effects you were experiencing.

  Function in the Body

And will I see any results and how does it function in the body?

Maribel (Editor)

Hello Karen. All users are different and can experience different weight-loss results.

  How it Works

How does it work I bought the product?

Maribel (Editor)

Hi Karen! For detailed product and usage instructions, please refer to the GNC 2-Day cleanse official website for more information.

blood detox

My spouse and I almost didn’t check this website out however I’m happy I have. That it is pretty good when compared to numerous others I’ve found. I will certainly be back.


I bought this to do a detox of nicotine. And from all the reviews its only saying for weight lose. So the guy at the GNC store in Tyler Tx lied or just didn’t know what he was talking about. Very disappointed that I spent the last of my money on this

GNC 2-Day Cleanse

becca!08/13/2012Costco has good vimatins. You might want to take an extra vimatin B6 or B12. They’re good for raising your energy level. Buy some frozen fruit and make a fruit smoothie that always gives me energy.