Updated: 01/17/2018

GNC 2-Day Cleanse Review - 6 Things You Need to Know


Why are people talking about GNC 2-Day Cleanse? We wanted to know, so we turned our attention toward ingredients, side effects, clinical research and customer service quality. Additionally, we analyzed hundreds of user comments and reviews. Then, we summarized and refined to give you the info you need.

GNC 2-Day Cleanse Readers: Click here to find out why we're giving away samples of our product, Burn HD.

What is GNC 2-Day Cleanse?

The GNC 2-Day Cleanse ingredients are purified water, juice cleanse blend, green coffee bean extract, garcinia cambogia fruit extract, green tea leaf extract, lychee, dandelion whole plant extract, mango fruit, burdock root, vitamins and minerals. [1] [2] It promotes weight-loss by removing toxins from the body and improving digestive health. You’ll drink one bottle, twice daily, prior to meals.

GNC is the company behind the product. They’ve been in the business for years, although GNC 2-Day Cleanse is relatively new. You can purchase the supplement on the official website or local stores. We like that contains a few natural ingredients and that we located some positive customer comments, but read on…

Products Similar to GNC 2-Day Cleanse

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Burn HD (Sample offer)read

Side Effects – “From Natural Ingredients?”

The first concern related to GNC 2-Day Cleanse side effects. “When we looked at this profile, we found it contained a few natural ingredients,” said our Research Editor. “After a closer look, we also noticed several of the components cause adverse reactions.”

“I could barely get the bottle down and even after I did I felt very sick to my stomach,” commented a customer. [3]

“It made me really gassy,” stated another. [4]

On the other hand, we found some dieters that didn’t experience negative side effects.

“It’s something that I wouldn’t be opposed to trying again down the road seeing as the side effects during it were minimal,” stated a consumer.

GNC 2-Day Cleanse Ingredients – “Nothing to Help You Lose?”

The GNC 2-Day Cleanse ingredients not producing results was a concern mentioned in customer reviews. “One star cause there’s no zero. Took the product as instructed. The only thing that was cleansed was my wallet.”

Another shared, “Tasted bad…did nothing for me…total waste of money.”

There were a few that did notice results, including some weight-loss.

“Easy to use, never hungry, lost 2.8 pounds in 2 days. Great way to jump start diet,” said a user.

What our research has told us that when any particular part of a supplement is considered troublesome, such as not supporting weight-loss, there’s a slim chance of long-term success. Is it really worth it if GNC 2-Day Cleanse doesn’t produce results.

The Science – “Backed by Research?”

The company offers no scientific proof that the GNC 2-Day Cleanse will in fact promote weight-loss, or enhance health in any area. While cleanses are generally recognized to offer some benefits, there is no actual research provided. We do know the act of increased bowel movements and water loss will change the scale, this is only temporary. [5] Here at DietSpotlight, we are looking for something that helps you lose more and we didn’t find that this time.

What Users Are Saying

"I buy this for my wife. She loves it!! It doesn’t handcuff her to the toilet for 3 days, but does the job."

"I liked it, not loved it. The detox was delayed by about 24 hours and when it did work it wasn’t as good as I thought it would be. It’s ok. Wouldn’t buy it again."

"The taste was tolerable, but I didn’t notice any difference during the cleanse."

The Bottom Line – Does GNC 2-Day Cleanse Work?

What’s our take on losing weight in 48 hours? Well, we like that GNC 2-Day Cleanse ingredients are natural and that the company has a foothold in the industry, but research supporting the claims leaves us concerned. We’re also a bit skeptical about this one because customers are talking about the lack of results and the harmful side effects.

We want you have long-term success, not just for 48 hours. So, we suggest going with a supplement containing ingredients shown to work, not linked to harmful side effects and supported by positive customer comments.

Among the best products we’ve seen this year is Dietspotlight Burn. The supplement promotes weight-loss by featuring four clinically-tested ingredients which have been shown to help accelerate metabolism and ignite weight-loss. There’s no one talking about harmful side effects, but there’s chatter about users seeing great results.

The makers of Dietspotlight Burn are so confident in their supplement, that they’re offering customers a special trial offer, truly impressive.

Learn More About Burn HD »
GNC 2-Day Cleanse Review
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What are the side effects of GNC 2-day Cleanse?

Possible GNC 2-day Cleanse side effects may include upset stomach, bloating, diarrhea, nausea and gas. This is based on customer reviews.

What are the ingredients in GNC 2-day Cleanse?

GNC 2-day Cleanse ingredients are purified water, whole apple concentrate, white grape extract, aloe vera gel, milk thistle extract, green tea leaf extract, citrus bioflavonoid complex, acai fruit, spirulina, grape skin extract, pineapple, apple, orange, chlorophyll, goji berry extract, broccoli, tomato, brussel sprouts, cauliflower, blueberry, grape, grapefruit, plum, raspberry, strawberry, watermelon, celery, kale, spinach, lemon, lime, papaya, cantaloupe, cherry, peach, pear, radish, onion, leek, yellow pepper, fibersol, maltodextrin soluble fiber, xanthan gum, apple pectin, carrot fiber, beet fiber, citric acid, potassium phosphate, natural flavors, potassium sorbate, sodium benxoate, calcium ascorbate, sucralose, niacin, d-calcium pantothenate, acesulfame potassium, folic acid, pyridoxine hcl, riboflavin, thiamin hcl, chlorella algae, kombu, wakame, nori, oat fiber, soybean fiber, brown rice, chicory root, Jerusalem artichoke tuber, acerola berry extract, licorice root extract, astragalus root, barley malt, mung bean, soy sprouts, wheat berry, eleuthero root extract, pomegranate fruit extract, cranberry concentrate, barley grass, jasmine tea extract, trace minerals, and cyanocobalamin. 

How do I know if GNC 2-Day Cleanse is right for me?

Choosing the right product is the #1 question asked by DietSpotlight readers. We recommend trying any product before buying it and know that finding a product with a sample offer is near impossible - so we created our own product, Burn HD, with scientifically backed ingredients.

Click here to get your sample of our powerful fat burner today.

Does GNC 2-day Cleanse work?

First off, this product contains five grams of fiber. This should help with more regular bowel movements. GNC 2-day Cleanse also contains various fruits and vegetables. These provide vitamins and minerals to help nourish the body. This formula contains antioxidants to help combat harmful free radicals. However, we did not find any clinical studies on the company website to support this cleansing drink as a means of promoting weight-loss.

You may want to consider replacing GNC 2-day Cleanse with a product that uses clinically tested ingredients for weight-loss. One option is Dietspotlight Burn.

How much does GNC 2-day Cleanse cost?

GNC 2-day Cleanse sells for $29.99. However, if you are a member, this product costs $26.99.

How should I take GNC 2-day Cleanse?

You only need to use GNC 2-day Cleanse for two days. It should be consumed twice a day, 30 minutes before meals. One 12-ounce bottle is a serving.

Is there a diet plan with GNC 2-day Cleanse?

Yes, there is a nutrition plan included on the box.

Can diabetics use GNC 2-day Cleanse?

You must consult your doctor to find out more.

GNC 2-Day Cleanse Ingredients

This is a 2-Day Juice Cleanse formulated to jump start a new diet plan. It removes unwanted toxins to jump start your metabolism.

GNC 2-Day Cleanse Ingredients and Supplement Facts

Serving Size: 1 Bottle
Serving Per Container: 4
Amount per Serving% DV
Vitamin A**
Vitamin C**
Vitamin E**
Vitamin B-6**
Vitamin B-12**
Pantothenic Acid**

Other Ingredients: None

  • References
  • 1. (). . .


Previous GNC 2-Day Cleanse Review (Updated August 14, 2012):

What You Should Know About GNC 2-Day Cleanse

GNC offers dieters a long list of products and supplements to lose weight, cleanse and build muscle, but not all products are safe and effective when it comes to promoting long-term weight loss. The GNC 2-Day Cleanse is a liquid cleanse that dieters use with natural, organic foods to reverse the damage caused by eating processed foods common in western diets. We found no clinical support that this cleanse would improve health or repair any part of the digestive or elimination systems of the body. There is also no proof the cleanse will increase weight loss.

List of Ingredients


  • Purified Water
  • Whole Apple Concentrate
  • White Grape Extract
  • Aloe Vera Gel
  • Milk Thistle Extract
  • Green Tea Leaf Extract
  • Citrus Bioflavonoid Complex
  • Acai Fruit
  • Spirulina
  • Grape Skin Extract
  • Pineapple
  • Apple
  • Orange
  • Chlorophyll
  • Goji Berry Extract
  • Broccoli
  • Tomato
  • Brussels Sprouts
  • Cauliflower
  • Blueberry
  • Grape
  • Grapefruit
  • Plum
  • Raspberry
  • Strawberry
  • Watermelon
  • Celery
  • Kale
  • Spinach
  • Lemon
  • Lime
  • Papaya
  • Cantaloupe
  • Cherry
  • Peach
  • Pear
  • Radish
  • Onion
  • Leek
  • Yellow Pepper
  • Fibersol
  • Maltodextrin Soluble Fiber
  • Xanthan Gum
  • Apple Pectin
  • Carrot Fiber
  • Beet Fiber
  • Citric Acid
  • Potassium Phosphate
  • Natural Flavors
  • Potassium Sorbate
  • Sodium Benzoate
  • Calcium Ascorbate
  • Sucralose
  • Niacin
  • D-Calcium Pantothenate
  • Acesulfame Potassium
  • Folic Acid
  • Pyridoxine HCL
  • Riboflavin
  • Thiamin HCL
  • Chlorella Algae
  • Kombu
  • Wakame
  • Nori
  • Oat Fiber
  • Soybean Fiber
  • Brown Rice
  • Chicory Root
  • Jerusalem Artichoke Tuber
  • Acerola Berry Extract
  • Licorice Root Extract
  • Astragalus Root
  • Barley Malt
  • Mung Bean
  • Soy Sprouts
  • Wheat Berry
  • Eleuthero Root Extract
  • Pomegranate Fruit Extract
  • Cranberry Concentrate
  • Barley Grass
  • Jasmine Tea Extract
  • Trace Minerals
  • Cyanocobalamin

Product Features: GNC 2-Day Cleanse

The list of ingredients for GNC 2-Day Cleanse is extraordinary, but the liquid concentrate supplies tons of vitamins via vegetables and fruits. There are several sources of fiber to promote cleansing, but the cleanse is natural as the sources of fiber are bulk-forming or lubricating and have no stimulant properties. GNC even adds potassium to the mix to replace any water lost from increased bowel movements and urination that may be associated with the intense push of fruit juices.

Advantages of GNC 2-Day Cleanse

  • Relatively healthy cleanse.
  • Supplies various sources of natural fiber.
  • May help kickstart a healthy eating plan.

Disadvantages of GNC 2-Day Cleanse

  • Will not necessarily promote weight loss.
  • The cleanse will have no effect if the dieter continues to eat processed, unhealthy foods.


In the cleansing market, GNC 2-Day Cleanse is one of the healthiest options a dieter can choose. The cleanse will increase urination and may increase bowel movements, but it will not cause diarrhea or loose stools like stimulant laxatives.

Summer Banks Dietspotlight Author
About the Author:

Summer Banks, Director of Content at Dietspotlight, has researched over 5000 weight-loss programs, pills, shakes and diet plans. Previously, she managed 15 supplement brands, worked with doctors specializing in weight loss and completed coursework in nutrition at Stanford University. full bio.

9 GNC 2-Day Cleanse Reviews

  •  Caused Throat sores
    Jen (Verified User)

    Careful! The day after finishing this 2 day cleanse I developed extremely painful sores on the back of my throat from the acidity.

  • Can this cause headaches?
    Your Name

    Can this cleanse cause headaches?

    • Maribel (Editor)

      Hi. Please make sure to consult with your physician before continuing to take this product and let them know about the side effects you were experiencing.

  • Function in the Body

    And will I see any results and how does it function in the body?

    • Maribel (Editor)

      Hello Karen. The fiber may help with more regular bowel movements, the vitamins/minerals may nourish the body and the antioxidants may help fight radicals. However, we didn’t find clinical studies connecting this product to weight-loss. You may want to try Dietspotlight Burn too, it uses clinically tested ingredients.

  • How it Works

    How does it work I bought the product?

  • blood detox

    My spouse and I almost didn’t check this website out however I’m happy I have. That it is pretty good when compared to numerous others I’ve found. I will certainly be back.

  • Chrystal

    I bought this to do a detox of nicotine. And from all the reviews its only saying for weight lose. So the guy at the GNC store in Tyler Tx lied or just didn’t know what he was talking about. Very disappointed that I spent the last of my money on this

  • GNC 2-Day Cleanse

    becca!08/13/2012Costco has good vimatins. You might want to take an extra vimatin B6 or B12. They’re good for raising your energy level. Buy some frozen fruit and make a fruit smoothie that always gives me energy.